Gene: EML4
Ensembl ID : ENSG00000143924
Description: EMAP like 4
Gene Synonyms: C2ORF2,ELP120,ROPP120
5 APIs:
214 Possible Orthologues:

ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK in cancer R-HSA-9700206
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Mitotic Prometaphase R-HSA-68877
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
ALK mutants bind TKIs R-HSA-9700645
Disease R-HSA-1643685
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK fusions and activated point mutants R-HSA-9725370
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Cell Cycle R-HSA-1640170
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
M Phase R-HSA-68886
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Cell Cycle, Mitotic R-HSA-69278
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Mitotic Prometaphase R-HSA-68877
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
ALK mutants bind TKIs R-HSA-9700645
M Phase R-HSA-68886
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK in cancer R-HSA-9700206
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Cell Cycle, Mitotic R-HSA-69278
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
ALK mutants bind TKIs R-HSA-9700645
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Mitotic Prometaphase R-HSA-68877
Cell Cycle, Mitotic R-HSA-69278
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
ALK mutants bind TKIs R-HSA-9700645
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by ALK in cancer R-HSA-9700206
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Signaling by ALK in cancer R-HSA-9700206
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Disease R-HSA-1643685
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Cell Cycle R-HSA-1640170
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
M Phase R-HSA-68886

Expression Atlas ENSG00000143924
NCBI gene (formerly Entrezgene) 27436
GeneCards 1316
HGNC Symbol HGNC:1316
MIM gene 607442
UniProtKB Gene Name Q9HC35
WikiGene 27436
Gene: MAP3K11
Ensembl ID : ENSG00000173327
Description: mitogen-activated protein kinase kinase kinase 11
Gene Synonyms: MEKK11,MLK3,PTK1,SPRK
1 APIs:
184 Possible Orthologues:

RAF activation R-HSA-5673000
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHOV GTPase cycle R-HSA-9013424
RAF/MAP kinase cascade R-HSA-5673001
Oncogenic MAPK signaling R-HSA-6802957
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
RHO GTPase cycle R-HSA-9012999
Signaling by RAS mutants R-HSA-6802949
Disease R-HSA-1643685
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
RHOG GTPase cycle R-HSA-9013408
MAPK family signaling cascades R-HSA-5683057
CDC42 GTPase cycle R-HSA-9013148
Signaling downstream of RAS mutants R-HSA-9649948
RAF activation R-HSA-5673000
MAPK1/MAPK3 signaling R-HSA-5684996
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHOV GTPase cycle R-HSA-9013424
MAPK family signaling cascades R-HSA-5683057
Signaling by RAS mutants R-HSA-6802949
RAF/MAP kinase cascade R-HSA-5673001
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
CDC42 GTPase cycle R-HSA-9013148
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
RHOG GTPase cycle R-HSA-9013408
RHO GTPase cycle R-HSA-9012999
RAF activation R-HSA-5673000
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Rho GTPases R-HSA-194315
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling downstream of RAS mutants R-HSA-9649948
Oncogenic MAPK signaling R-HSA-6802957
Disease R-HSA-1643685
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RAF activation R-HSA-5673000
Signal Transduction R-HSA-162582
RAF/MAP kinase cascade R-HSA-5673001
RHO GTPase cycle R-HSA-9012999
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
CDC42 GTPase cycle R-HSA-9013148
Signaling by RAS mutants R-HSA-6802949
RHOG GTPase cycle R-HSA-9013408
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHOV GTPase cycle R-HSA-9013424
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by Rho GTPases R-HSA-194315
Disease R-HSA-1643685
Oncogenic MAPK signaling R-HSA-6802957
Oncogenic MAPK signaling R-HSA-6802957
Signaling downstream of RAS mutants R-HSA-9649948
Signal Transduction R-HSA-162582
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RHOG GTPase cycle R-HSA-9013408
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF activation R-HSA-5673000
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Rho GTPases R-HSA-194315
RHO GTPase cycle R-HSA-9012999
RAF/MAP kinase cascade R-HSA-5673001
CDC42 GTPase cycle R-HSA-9013148
RHOV GTPase cycle R-HSA-9013424
Signaling by RAS mutants R-HSA-6802949
RHO GTPase cycle R-HSA-9012999
Signal Transduction R-HSA-162582
RHOV GTPase cycle R-HSA-9013424
Signaling downstream of RAS mutants R-HSA-9649948
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
MAPK family signaling cascades R-HSA-5683057
Signaling by RAS mutants R-HSA-6802949
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Oncogenic MAPK signaling R-HSA-6802957
CDC42 GTPase cycle R-HSA-9013148
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signaling by Rho GTPases R-HSA-194315
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RHOG GTPase cycle R-HSA-9013408
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
CDC42 GTPase cycle R-HSA-9013148
Signaling by RAS mutants R-HSA-6802949
Signaling downstream of RAS mutants R-HSA-9649948
MAPK1/MAPK3 signaling R-HSA-5684996
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RHOG GTPase cycle R-HSA-9013408
Signaling by Rho GTPases R-HSA-194315
RHOV GTPase cycle R-HSA-9013424
Disease R-HSA-1643685
RHO GTPase cycle R-HSA-9012999
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
RAF activation R-HSA-5673000
Signal Transduction R-HSA-162582
Oncogenic MAPK signaling R-HSA-6802957
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
CDC42 GTPase cycle R-HSA-9013148
RHOG GTPase cycle R-HSA-9013408
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
MAPK family signaling cascades R-HSA-5683057
Oncogenic MAPK signaling R-HSA-6802957
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
RHOV GTPase cycle R-HSA-9013424
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Signaling by RAS mutants R-HSA-6802949
Signaling downstream of RAS mutants R-HSA-9649948
RHO GTPase cycle R-HSA-9012999
Signaling by Rho GTPases R-HSA-194315
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF activation R-HSA-5673000
Oncogenic MAPK signaling R-HSA-6802957
Disease R-HSA-1643685
Signaling downstream of RAS mutants R-HSA-9649948
RAF activation R-HSA-5673000
RAF/MAP kinase cascade R-HSA-5673001
Signaling by RAS mutants R-HSA-6802949
RHOV GTPase cycle R-HSA-9013424
RHO GTPase cycle R-HSA-9012999
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
CDC42 GTPase cycle R-HSA-9013148
RHOG GTPase cycle R-HSA-9013408
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Oncogenic MAPK signaling R-HSA-6802957
Disease R-HSA-1643685
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
CDC42 GTPase cycle R-HSA-9013148
Signal Transduction R-HSA-162582
RAF activation R-HSA-5673000
Signaling downstream of RAS mutants R-HSA-9649948
RHOV GTPase cycle R-HSA-9013424
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Rho GTPases R-HSA-194315
RAF/MAP kinase cascade R-HSA-5673001
RHO GTPase cycle R-HSA-9012999
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHOG GTPase cycle R-HSA-9013408
Signaling by RAS mutants R-HSA-6802949
MAPK family signaling cascades R-HSA-5683057
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542

Expression Atlas ENSG00000173327
NCBI gene (formerly Entrezgene) 4296
GeneCards 6850
HGNC Symbol HGNC:6850
MIM gene 600050
UniProtKB Gene Name Q16584
WikiGene 4296
Gene: ADRM1
Ensembl ID : ENSG00000130706
Description: ADRM1 26S proteasome ubiquitin receptor
Gene Synonyms: ARM1,GP110,PSMD16,RPN13
5 APIs:
261 Possible Orthologues:

Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
Deubiquitination R-HSA-5688426
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
UCH proteinases R-HSA-5689603
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592

Expression Atlas ENSG00000130706
NCBI gene (formerly Entrezgene) 11047
GeneCards 15759
HGNC Symbol HGNC:15759
MIM gene 610650
UniProtKB Gene Name Q16186
WikiGene 11047
Gene: PSMD1
Ensembl ID : ENSG00000173692
Description: proteasome 26S subunit, non-ATPase 1
Gene Synonyms: P112,RPN2,S1
5 APIs:
211 Possible Orthologues:

Degradation of DVL R-HSA-4641258
Separation of Sister Chromatids R-HSA-2467813
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog ligand biogenesis R-HSA-5358346
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
Hedgehog 'off' state R-HSA-5610787
Metabolism R-HSA-1430728
MAPK family signaling cascades R-HSA-5683057
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
S Phase R-HSA-69242
Metabolism of proteins R-HSA-392499
PCP/CE pathway R-HSA-4086400
PTEN Regulation R-HSA-6807070
Transport of small molecules R-HSA-382551
Immune System R-HSA-168256
Programmed Cell Death R-HSA-5357801
Activation of NF-kappaB in B cells R-HSA-1169091
Stabilization of p53 R-HSA-69541
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'on' state R-HSA-5632684
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-1 signaling R-HSA-9020702
Assembly of the pre-replicative complex R-HSA-68867
Signaling by ROBO receptors R-HSA-376176
Nuclear events mediated by NFE2L2 R-HSA-9759194
ABC-family proteins mediated transport R-HSA-382556
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of polyamines R-HSA-351202
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Interleukins R-HSA-449147
M Phase R-HSA-68886
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Vpu mediated degradation of CD4 R-HSA-180534
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
Downstream TCR signaling R-HSA-202424
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of mitotic cell cycle R-HSA-453276
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S Transition R-HSA-69206
Neutrophil degranulation R-HSA-6798695
TCF dependent signaling in response to WNT R-HSA-201681
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
Orc1 removal from chromatin R-HSA-68949
MAPK1/MAPK3 signaling R-HSA-5684996
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ER-Phagosome pathway R-HSA-1236974
Cellular responses to stress R-HSA-2262752
MAPK6/MAPK4 signaling R-HSA-5687128
Disease R-HSA-1643685
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent DNA Damage Response R-HSA-69610
PIP3 activates AKT signaling R-HSA-1257604
Cellular response to hypoxia R-HSA-1234174
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Axon guidance R-HSA-422475
Degradation of AXIN R-HSA-4641257
Signaling by NOTCH R-HSA-157118
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of Apoptosis R-HSA-169911
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of RNA R-HSA-8953854
Switching of origins to a post-replicative state R-HSA-69052
Gene expression (Transcription) R-HSA-74160
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
CLEC7A (Dectin-1) signaling R-HSA-5607764
Synthesis of DNA R-HSA-69239
DNA Replication R-HSA-69306
TCR signaling R-HSA-202403
Regulation of RAS by GAPs R-HSA-5658442
Interleukin-1 family signaling R-HSA-446652
G2/M Transition R-HSA-69275
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Class I MHC mediated antigen processing & presentation R-HSA-983169
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Antigen processing-Cross presentation R-HSA-1236975
C-type lectin receptors (CLRs) R-HSA-5621481
Cytokine Signaling in Immune system R-HSA-1280215
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of DVL R-HSA-4641258
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
Neddylation R-HSA-8951664
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX3 expression and activity R-HSA-8941858
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Infectious disease R-HSA-5663205
Signaling by Hedgehog R-HSA-5358351
Mitotic G2-G2/M phases R-HSA-453274
Cellular response to chemical stress R-HSA-9711123
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
HIV Infection R-HSA-162906
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by WNT R-HSA-195721
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Host Interactions of HIV factors R-HSA-162909
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Innate Immune System R-HSA-168249
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX3 R-HSA-8878159
Ub-specific processing proteases R-HSA-5689880
Mitotic G1 phase and G1/S transition R-HSA-453279
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
NIK-->noncanonical NF-kB signaling R-HSA-5676590
FCERI mediated NF-kB activation R-HSA-2871837
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by Interleukins R-HSA-449147
Disease R-HSA-1643685
Degradation of GLI1 by the proteasome R-HSA-5610780
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
DNA Replication R-HSA-69306
UCH proteinases R-HSA-5689603
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'off' state R-HSA-5610787
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G2-G2/M phases R-HSA-453274
Antigen processing-Cross presentation R-HSA-1236975
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Neutrophil degranulation R-HSA-6798695
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular response to chemical stress R-HSA-9711123
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cell Cycle Checkpoints R-HSA-69620
FCERI mediated NF-kB activation R-HSA-2871837
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Separation of Sister Chromatids R-HSA-2467813
Generic Transcription Pathway R-HSA-212436
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by WNT R-HSA-195721
Stabilization of p53 R-HSA-69541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Host Interactions of HIV factors R-HSA-162909
Vif-mediated degradation of APOBEC3G R-HSA-180585
Downstream TCR signaling R-HSA-202424
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX3 R-HSA-8878159
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
ABC-family proteins mediated transport R-HSA-382556
ABC transporter disorders R-HSA-5619084
MAPK6/MAPK4 signaling R-HSA-5687128
Disorders of transmembrane transporters R-HSA-5619115
Signal Transduction R-HSA-162582
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stimuli R-HSA-8953897
HIV Infection R-HSA-162906
Intracellular signaling by second messengers R-HSA-9006925
Degradation of AXIN R-HSA-4641257
Signaling by NOTCH R-HSA-157118
Degradation of DVL R-HSA-4641258
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stress R-HSA-2262752
Infectious disease R-HSA-5663205
Deubiquitination R-HSA-5688426
Beta-catenin independent WNT signaling R-HSA-3858494
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Programmed Cell Death R-HSA-5357801
Metabolism of amino acids and derivatives R-HSA-71291
Innate Immune System R-HSA-168249
Signaling by Hedgehog R-HSA-5358351
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S DNA Damage Checkpoints R-HSA-69615
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Nervous system development R-HSA-9675108
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of RNA R-HSA-8953854
Regulation of RAS by GAPs R-HSA-5658442
Switching of origins to a post-replicative state R-HSA-69052
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH4 R-HSA-9013694
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of Apoptosis R-HSA-169911
Mitotic Metaphase and Anaphase R-HSA-2555396
PTEN Regulation R-HSA-6807070
Regulation of RUNX2 expression and activity R-HSA-8939902
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
C-type lectin receptors (CLRs) R-HSA-5621481
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TCR signaling R-HSA-202403
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Adaptive Immune System R-HSA-1280218
Interleukin-1 family signaling R-HSA-446652
Cell Cycle, Mitotic R-HSA-69278
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Asymmetric localization of PCP proteins R-HSA-4608870
KEAP1-NFE2L2 pathway R-HSA-9755511
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Synthesis of DNA R-HSA-69239
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent DNA Damage Response R-HSA-69610
Developmental Biology R-HSA-1266738
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog 'on' state R-HSA-5632684
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of PTEN stability and activity R-HSA-8948751
p53-Dependent G1 DNA Damage Response R-HSA-69563
G2/M Transition R-HSA-69275
Cytokine Signaling in Immune system R-HSA-1280215
DNA Replication Pre-Initiation R-HSA-69002
ER-Phagosome pathway R-HSA-1236974
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Anaphase R-HSA-68882
Metabolism of proteins R-HSA-392499
PCP/CE pathway R-HSA-4086400
Metabolism R-HSA-1430728
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TCF dependent signaling in response to WNT R-HSA-201681
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to hypoxia R-HSA-1234174
MAPK1/MAPK3 signaling R-HSA-5684996
Orc1 removal from chromatin R-HSA-68949
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog ligand biogenesis R-HSA-5358346
MAPK family signaling cascades R-HSA-5683057
G1/S Transition R-HSA-69206
Signaling by ROBO receptors R-HSA-376176
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stimuli R-HSA-8953897
Downstream TCR signaling R-HSA-202424
Infectious disease R-HSA-5663205
Regulation of expression of SLITs and ROBOs R-HSA-9010553
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic Anaphase R-HSA-68882
TCF dependent signaling in response to WNT R-HSA-201681
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX3 R-HSA-8878159
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent DNA Damage Response R-HSA-69610
Mitotic G2-G2/M phases R-HSA-453274
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle R-HSA-1640170
Synthesis of DNA R-HSA-69239
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of RAS by GAPs R-HSA-5658442
ER-Phagosome pathway R-HSA-1236974
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
MAPK family signaling cascades R-HSA-5683057
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog ligand biogenesis R-HSA-5358346
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Antigen processing-Cross presentation R-HSA-1236975
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 signaling R-HSA-9020702
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle, Mitotic R-HSA-69278
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
Metabolism of proteins R-HSA-392499
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Innate Immune System R-HSA-168249
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hh mutants abrogate ligand secretion R-HSA-5387390
MAPK6/MAPK4 signaling R-HSA-5687128
Hh mutants are degraded by ERAD R-HSA-5362768
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK1/MAPK3 signaling R-HSA-5684996
PIP3 activates AKT signaling R-HSA-1257604
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
HIV Infection R-HSA-162906
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
M Phase R-HSA-68886
Assembly of the pre-replicative complex R-HSA-68867
Cell Cycle Checkpoints R-HSA-69620
Hedgehog 'on' state R-HSA-5632684
Developmental Biology R-HSA-1266738
Degradation of AXIN R-HSA-4641257
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disease R-HSA-1643685
Regulation of PTEN stability and activity R-HSA-8948751
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RUNX2 expression and activity R-HSA-8939902
Switching of origins to a post-replicative state R-HSA-69052
C-type lectin receptors (CLRs) R-HSA-5621481
G2/M Checkpoints R-HSA-69481
Signaling by ROBO receptors R-HSA-376176
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Post-translational protein modification R-HSA-597592
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Dependent G1 DNA Damage Response R-HSA-69563
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH R-HSA-157118
Orc1 removal from chromatin R-HSA-68949
Degradation of beta-catenin by the destruction complex R-HSA-195253
KEAP1-NFE2L2 pathway R-HSA-9755511
ABC transporter disorders R-HSA-5619084
Regulation of mitotic cell cycle R-HSA-453276
Cellular responses to stress R-HSA-2262752
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PTEN Regulation R-HSA-6807070
Neutrophil degranulation R-HSA-6798695
Metabolism of polyamines R-HSA-351202
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ub-specific processing proteases R-HSA-5689880
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
RNA Polymerase II Transcription R-HSA-73857
PCP/CE pathway R-HSA-4086400
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'off' state R-HSA-5610787
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism R-HSA-1430728
Signaling by Hedgehog R-HSA-5358351
DNA Replication Pre-Initiation R-HSA-69002
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Beta-catenin independent WNT signaling R-HSA-3858494
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX2 R-HSA-8878166
Separation of Sister Chromatids R-HSA-2467813
Disorders of transmembrane transporters R-HSA-5619115
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
DNA Replication R-HSA-69306
Deubiquitination R-HSA-5688426
Signaling by NOTCH4 R-HSA-9013694
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
S Phase R-HSA-69242
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S DNA Damage Checkpoints R-HSA-69615
Programmed Cell Death R-HSA-5357801
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G1/S Transition R-HSA-69206
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Nervous system development R-HSA-9675108
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by WNT R-HSA-195721
Neddylation R-HSA-8951664
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transport of small molecules R-HSA-382551
Host Interactions of HIV factors R-HSA-162909
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of Apoptosis R-HSA-169911
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
M Phase R-HSA-68886
Regulation of Apoptosis R-HSA-169911
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Hedgehog R-HSA-5358351
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Host Interactions of HIV factors R-HSA-162909
Antigen processing-Cross presentation R-HSA-1236975
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Metaphase and Anaphase R-HSA-2555396
HIV Infection R-HSA-162906
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PCP/CE pathway R-HSA-4086400
ABC transporter disorders R-HSA-5619084
Hh mutants are degraded by ERAD R-HSA-5362768
ABC-family proteins mediated transport R-HSA-382556
Regulation of PTEN stability and activity R-HSA-8948751
Adaptive Immune System R-HSA-1280218
Metabolism of RNA R-HSA-8953854
Neutrophil degranulation R-HSA-6798695
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Deubiquitination R-HSA-5688426
G2/M Transition R-HSA-69275
S Phase R-HSA-69242
Degradation of AXIN R-HSA-4641257
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK6/MAPK4 signaling R-HSA-5687128
Programmed Cell Death R-HSA-5357801
Signaling by ROBO receptors R-HSA-376176
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by NOTCH4 R-HSA-9013694
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle R-HSA-1640170
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
MAPK family signaling cascades R-HSA-5683057
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH R-HSA-157118
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TCF dependent signaling in response to WNT R-HSA-201681
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular response to chemical stress R-HSA-9711123
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX2 R-HSA-8878166
Interleukin-1 signaling R-HSA-9020702
Cyclin E associated events during G1/S transition R-HSA-69202
Transport of small molecules R-HSA-382551
Nervous system development R-HSA-9675108
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
Metabolism of proteins R-HSA-392499
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Innate Immune System R-HSA-168249
Degradation of DVL R-HSA-4641258
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
Stabilization of p53 R-HSA-69541
Regulation of mitotic cell cycle R-HSA-453276
Axon guidance R-HSA-422475
p53-Independent DNA Damage Response R-HSA-69610
Cellular responses to stress R-HSA-2262752
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Post-translational protein modification R-HSA-597592
Synthesis of DNA R-HSA-69239
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Anaphase R-HSA-68882
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication R-HSA-69306
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Developmental Biology R-HSA-1266738
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hedgehog 'on' state R-HSA-5632684
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism R-HSA-1430728
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 family signaling R-HSA-446652
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RUNX3 expression and activity R-HSA-8941858
ER-Phagosome pathway R-HSA-1236974
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
Ub-specific processing proteases R-HSA-5689880
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PTEN Regulation R-HSA-6807070
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle, Mitotic R-HSA-69278
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Nuclear events mediated by NFE2L2 R-HSA-9759194
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Hedgehog 'off' state R-HSA-5610787
Metabolism of polyamines R-HSA-351202
Assembly of the pre-replicative complex R-HSA-68867
Orc1 removal from chromatin R-HSA-68949
Cellular responses to stimuli R-HSA-8953897
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of RAS by GAPs R-HSA-5658442
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Generic Transcription Pathway R-HSA-212436
p53-Dependent G1 DNA Damage Response R-HSA-69563
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Apoptosis R-HSA-109581
DNA Replication Pre-Initiation R-HSA-69002
Signaling by WNT R-HSA-195721
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PIP3 activates AKT signaling R-HSA-1257604
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
RAF/MAP kinase cascade R-HSA-5673001
KEAP1-NFE2L2 pathway R-HSA-9755511
CLEC7A (Dectin-1) signaling R-HSA-5607764
Switching of origins to a post-replicative state R-HSA-69052
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by Interleukins R-HSA-449147
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by the B Cell Receptor (BCR) R-HSA-983705
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
G1/S Transition R-HSA-69206
Degradation of beta-catenin by the destruction complex R-HSA-195253
TCR signaling R-HSA-202403
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle Checkpoints R-HSA-69620
UCH proteinases R-HSA-5689603
Metabolism of amino acids and derivatives R-HSA-71291
Disorders of transmembrane transporters R-HSA-5619115
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional regulation by RUNX3 R-HSA-8878159
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Vif-mediated degradation of APOBEC3G R-HSA-180585
Class I MHC mediated antigen processing & presentation R-HSA-983169
Asymmetric localization of PCP proteins R-HSA-4608870
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cyclin E associated events during G1/S transition R-HSA-69202
Activation of NF-kappaB in B cells R-HSA-1169091
Deubiquitination R-HSA-5688426
Degradation of GLI1 by the proteasome R-HSA-5610780
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
Signaling by NOTCH4 R-HSA-9013694
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular response to hypoxia R-HSA-1234174
Nuclear events mediated by NFE2L2 R-HSA-9759194
MAPK family signaling cascades R-HSA-5683057
Metabolism R-HSA-1430728
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
DNA Replication R-HSA-69306
Interleukin-1 signaling R-HSA-9020702
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Programmed Cell Death R-HSA-5357801
Downstream TCR signaling R-HSA-202424
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hh mutants are degraded by ERAD R-HSA-5362768
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Ub-specific processing proteases R-HSA-5689880
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transport of small molecules R-HSA-382551
Transcriptional regulation by RUNX2 R-HSA-8878166
M Phase R-HSA-68886
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of GLI2 by the proteasome R-HSA-5610783
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Stabilization of p53 R-HSA-69541
Signaling by Hedgehog R-HSA-5358351
Regulation of mitotic cell cycle R-HSA-453276
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Independent DNA Damage Response R-HSA-69610
Adaptive Immune System R-HSA-1280218
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by WNT R-HSA-195721
Switching of origins to a post-replicative state R-HSA-69052
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'off' state R-HSA-5610787
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
G1/S DNA Damage Checkpoints R-HSA-69615
RAF/MAP kinase cascade R-HSA-5673001
Post-translational protein modification R-HSA-597592
G2/M Transition R-HSA-69275
Immune System R-HSA-168256
Cellular response to chemical stress R-HSA-9711123
Axon guidance R-HSA-422475
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing-Cross presentation R-HSA-1236975
Mitotic Metaphase and Anaphase R-HSA-2555396
ABC transporter disorders R-HSA-5619084
Apoptosis R-HSA-109581
Intracellular signaling by second messengers R-HSA-9006925
ABC-family proteins mediated transport R-HSA-382556
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
S Phase R-HSA-69242
FCERI mediated NF-kB activation R-HSA-2871837
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Host Interactions of HIV factors R-HSA-162909
Degradation of AXIN R-HSA-4641257
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
ER-Phagosome pathway R-HSA-1236974
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Anaphase R-HSA-68882
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by ROBO receptors R-HSA-376176
Generic Transcription Pathway R-HSA-212436
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic G1 phase and G1/S transition R-HSA-453279
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
HIV Infection R-HSA-162906
TCR signaling R-HSA-202403
Infectious disease R-HSA-5663205
G1/S Transition R-HSA-69206
Cell Cycle Checkpoints R-HSA-69620
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of RAS by GAPs R-HSA-5658442
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by NOTCH R-HSA-157118
Synthesis of DNA R-HSA-69239
TCF dependent signaling in response to WNT R-HSA-201681
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Nervous system development R-HSA-9675108
Regulation of RUNX2 expression and activity R-HSA-8939902
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
Separation of Sister Chromatids R-HSA-2467813
Negative regulation of NOTCH4 signaling R-HSA-9604323
G2/M Checkpoints R-HSA-69481
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Neutrophil degranulation R-HSA-6798695
DNA Replication Pre-Initiation R-HSA-69002
Neddylation R-HSA-8951664
Degradation of DVL R-HSA-4641258
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of polyamines R-HSA-351202
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of beta-catenin by the destruction complex R-HSA-195253
UCH proteinases R-HSA-5689603
Signaling by Interleukins R-HSA-449147
Regulation of RUNX3 expression and activity R-HSA-8941858
Vpu mediated degradation of CD4 R-HSA-180534
Orc1 removal from chromatin R-HSA-68949
PTEN Regulation R-HSA-6807070
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stimuli R-HSA-8953897
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of expression of SLITs and ROBOs R-HSA-9010553
RNA Polymerase II Transcription R-HSA-73857
Signaling by Hedgehog R-HSA-5358351
G2/M Checkpoints R-HSA-69481
Metabolism of RNA R-HSA-8953854
Cellular responses to stress R-HSA-2262752
Signaling by Interleukins R-HSA-449147
Signaling by WNT R-HSA-195721
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Innate Immune System R-HSA-168249
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by NOTCH R-HSA-157118
Hh mutants are degraded by ERAD R-HSA-5362768
Transport of small molecules R-HSA-382551
Neddylation R-HSA-8951664
Disorders of transmembrane transporters R-HSA-5619115
Nuclear events mediated by NFE2L2 R-HSA-9759194
Infectious disease R-HSA-5663205
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular response to hypoxia R-HSA-1234174
Axon guidance R-HSA-422475
p53-Dependent G1 DNA Damage Response R-HSA-69563
Vpu mediated degradation of CD4 R-HSA-180534
S Phase R-HSA-69242
Separation of Sister Chromatids R-HSA-2467813
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication Pre-Initiation R-HSA-69002
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by ROBO receptors R-HSA-376176
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Metabolism R-HSA-1430728
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of AXIN R-HSA-4641257
Assembly of the pre-replicative complex R-HSA-68867
Hedgehog 'on' state R-HSA-5632684
Disease R-HSA-1643685
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nervous system development R-HSA-9675108
Degradation of DVL R-HSA-4641258
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle R-HSA-1640170
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Orc1 removal from chromatin R-HSA-68949
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic Anaphase R-HSA-68882
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle, Mitotic R-HSA-69278
Programmed Cell Death R-HSA-5357801
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Neutrophil degranulation R-HSA-6798695
Intracellular signaling by second messengers R-HSA-9006925
C-type lectin receptors (CLRs) R-HSA-5621481
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
PIP3 activates AKT signaling R-HSA-1257604
HIV Infection R-HSA-162906
Negative regulation of NOTCH4 signaling R-HSA-9604323
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Deubiquitination R-HSA-5688426
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
TCF dependent signaling in response to WNT R-HSA-201681
Signal Transduction R-HSA-162582
p53-Independent DNA Damage Response R-HSA-69610
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RUNX3 expression and activity R-HSA-8941858
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ABC-family proteins mediated transport R-HSA-382556
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCR signaling R-HSA-202403
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transcriptional regulation by RUNX3 R-HSA-8878159
Class I MHC mediated antigen processing & presentation R-HSA-983169
Beta-catenin independent WNT signaling R-HSA-3858494
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream TCR signaling R-HSA-202424
Hedgehog 'off' state R-HSA-5610787
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of Apoptosis R-HSA-169911
Regulation of mitotic cell cycle R-HSA-453276
Cellular responses to stimuli R-HSA-8953897
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Generic Transcription Pathway R-HSA-212436
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
RAF/MAP kinase cascade R-HSA-5673001
Apoptosis R-HSA-109581
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
M Phase R-HSA-68886
Synthesis of DNA R-HSA-69239
Interleukin-1 signaling R-HSA-9020702
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cyclin E associated events during G1/S transition R-HSA-69202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of amino acids and derivatives R-HSA-71291
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Cell Cycle Checkpoints R-HSA-69620
Asymmetric localization of PCP proteins R-HSA-4608870
Developmental Biology R-HSA-1266738
ER-Phagosome pathway R-HSA-1236974
Metabolism of proteins R-HSA-392499
Mitotic G2-G2/M phases R-HSA-453274
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog ligand biogenesis R-HSA-5358346
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Cellular response to chemical stress R-HSA-9711123
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of GLI1 by the proteasome R-HSA-5610780
Switching of origins to a post-replicative state R-HSA-69052
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Gene expression (Transcription) R-HSA-74160
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of Apoptosis R-HSA-169911
Degradation of AXIN R-HSA-4641257
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hedgehog 'on' state R-HSA-5632684
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle, Mitotic R-HSA-69278
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
Signaling by Hedgehog R-HSA-5358351
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ER-Phagosome pathway R-HSA-1236974
Cell Cycle Checkpoints R-HSA-69620
Intracellular signaling by second messengers R-HSA-9006925
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle R-HSA-1640170
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Signaling by NOTCH4 R-HSA-9013694
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of RUNX3 expression and activity R-HSA-8941858
TCF dependent signaling in response to WNT R-HSA-201681
ABC transporter disorders R-HSA-5619084
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
Synthesis of DNA R-HSA-69239
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX3 R-HSA-8878159
Neddylation R-HSA-8951664
Post-translational protein modification R-HSA-597592
Deubiquitination R-HSA-5688426
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of GLI2 by the proteasome R-HSA-5610783
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G1/S Transition R-HSA-69206
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Interleukins R-HSA-449147
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Defective CFTR causes cystic fibrosis R-HSA-5678895
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of PTEN stability and activity R-HSA-8948751
Infectious disease R-HSA-5663205
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
Ub-specific processing proteases R-HSA-5689880
Cyclin E associated events during G1/S transition R-HSA-69202
Hh mutants abrogate ligand secretion R-HSA-5387390
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog 'off' state R-HSA-5610787
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK6/MAPK4 signaling R-HSA-5687128
PTEN Regulation R-HSA-6807070
RAF/MAP kinase cascade R-HSA-5673001
Adaptive Immune System R-HSA-1280218
G2/M Checkpoints R-HSA-69481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
C-type lectin receptors (CLRs) R-HSA-5621481
Neutrophil degranulation R-HSA-6798695
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
MAPK1/MAPK3 signaling R-HSA-5684996
Programmed Cell Death R-HSA-5357801
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Beta-catenin independent WNT signaling R-HSA-3858494
p53-Independent DNA Damage Response R-HSA-69610
Disorders of transmembrane transporters R-HSA-5619115
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Activation of NF-kappaB in B cells R-HSA-1169091
Downstream TCR signaling R-HSA-202424
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Mitotic Metaphase and Anaphase R-HSA-2555396
Nervous system development R-HSA-9675108
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 signaling R-HSA-9020702
Generic Transcription Pathway R-HSA-212436
DNA Replication R-HSA-69306
Immune System R-HSA-168256
Cellular responses to stress R-HSA-2262752
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cytokine Signaling in Immune system R-HSA-1280215
Apoptosis R-HSA-109581
Metabolism of polyamines R-HSA-351202
G2/M Transition R-HSA-69275
Nuclear events mediated by NFE2L2 R-HSA-9759194
Orc1 removal from chromatin R-HSA-68949
Regulation of mitotic cell cycle R-HSA-453276
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Switching of origins to a post-replicative state R-HSA-69052
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Vpu mediated degradation of CD4 R-HSA-180534
S Phase R-HSA-69242
Degradation of DVL R-HSA-4641258
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by WNT R-HSA-195721
Regulation of RAS by GAPs R-HSA-5658442
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PCP/CE pathway R-HSA-4086400
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hh mutants are degraded by ERAD R-HSA-5362768
Transport of small molecules R-HSA-382551
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX1 R-HSA-8878171
Stabilization of p53 R-HSA-69541
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular responses to stimuli R-HSA-8953897
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
Host Interactions of HIV factors R-HSA-162909
Metabolism R-HSA-1430728
Interleukin-1 family signaling R-HSA-446652
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of RNA R-HSA-8953854
Ub-specific processing proteases R-HSA-5689880
Signaling by ROBO receptors R-HSA-376176
Metabolism of proteins R-HSA-392499
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
Hh mutants are degraded by ERAD R-HSA-5362768
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'on' state R-HSA-5632684
Metabolism R-HSA-1430728
Degradation of GLI1 by the proteasome R-HSA-5610780
PIP3 activates AKT signaling R-HSA-1257604
DNA Replication R-HSA-69306
Disease R-HSA-1643685
Metabolism of polyamines R-HSA-351202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Synthesis of DNA R-HSA-69239
Programmed Cell Death R-HSA-5357801
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stress R-HSA-2262752
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Innate Immune System R-HSA-168249
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Metaphase and Anaphase R-HSA-2555396
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of Apoptosis R-HSA-169911
Cyclin E associated events during G1/S transition R-HSA-69202
Orc1 removal from chromatin R-HSA-68949
Degradation of DVL R-HSA-4641258
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
Neddylation R-HSA-8951664
FCERI mediated NF-kB activation R-HSA-2871837
G2/M Checkpoints R-HSA-69481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Intracellular signaling by second messengers R-HSA-9006925
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK1/MAPK3 signaling R-HSA-5684996
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RAS by GAPs R-HSA-5658442
Mitotic G2-G2/M phases R-HSA-453274
Apoptosis R-HSA-109581
PCP/CE pathway R-HSA-4086400
Signaling by Hedgehog R-HSA-5358351
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stimuli R-HSA-8953897
PTEN Regulation R-HSA-6807070
Cellular response to chemical stress R-HSA-9711123
Transport of small molecules R-HSA-382551
Cell Cycle R-HSA-1640170
Class I MHC mediated antigen processing & presentation R-HSA-983169
Signaling by WNT R-HSA-195721
p53-Independent DNA Damage Response R-HSA-69610
ER-Phagosome pathway R-HSA-1236974
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream TCR signaling R-HSA-202424
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of AXIN R-HSA-4641257
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK6/MAPK4 signaling R-HSA-5687128
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Interleukin-1 signaling R-HSA-9020702
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX3 R-HSA-8878159
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Deubiquitination R-HSA-5688426
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by NOTCH4 R-HSA-9013694
Disorders of transmembrane transporters R-HSA-5619115
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Host Interactions of HIV factors R-HSA-162909
Mitotic G1 phase and G1/S transition R-HSA-453279
HIV Infection R-HSA-162906
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Adaptive Immune System R-HSA-1280218
Gene expression (Transcription) R-HSA-74160
Degradation of GLI2 by the proteasome R-HSA-5610783
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Vpu mediated degradation of CD4 R-HSA-180534
G1/S Transition R-HSA-69206
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH R-HSA-157118
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ABC-family proteins mediated transport R-HSA-382556
Nervous system development R-HSA-9675108
TCR signaling R-HSA-202403
Infectious disease R-HSA-5663205
Cell Cycle Checkpoints R-HSA-69620
Neutrophil degranulation R-HSA-6798695
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
G2/M Transition R-HSA-69275
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
DNA Replication Pre-Initiation R-HSA-69002
Vif-mediated degradation of APOBEC3G R-HSA-180585
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signal Transduction R-HSA-162582
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
UCH proteinases R-HSA-5689603
Degradation of beta-catenin by the destruction complex R-HSA-195253
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
Switching of origins to a post-replicative state R-HSA-69052
Mitotic Anaphase R-HSA-68882
Beta-catenin independent WNT signaling R-HSA-3858494
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
G2/M Checkpoints R-HSA-69481
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RNA Polymerase II Transcription R-HSA-73857
ABC transporter disorders R-HSA-5619084
Axon guidance R-HSA-422475
HIV Infection R-HSA-162906
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of Apoptosis R-HSA-169911
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
PCP/CE pathway R-HSA-4086400
Degradation of DVL R-HSA-4641258
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog 'on' state R-HSA-5632684
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
UCH proteinases R-HSA-5689603
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cytokine Signaling in Immune system R-HSA-1280215
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH R-HSA-157118
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
Infectious disease R-HSA-5663205
Nuclear events mediated by NFE2L2 R-HSA-9759194
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Deubiquitination R-HSA-5688426
ER-Phagosome pathway R-HSA-1236974
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
Cell Cycle, Mitotic R-HSA-69278
Mitotic Anaphase R-HSA-68882
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CLEC7A (Dectin-1) signaling R-HSA-5607764
Developmental Biology R-HSA-1266738
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to chemical stress R-HSA-9711123
Orc1 removal from chromatin R-HSA-68949
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle Checkpoints R-HSA-69620
FCERI mediated NF-kB activation R-HSA-2871837
p53-Dependent G1 DNA Damage Response R-HSA-69563
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic Metaphase and Anaphase R-HSA-2555396
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S Transition R-HSA-69206
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
TCF dependent signaling in response to WNT R-HSA-201681
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by WNT R-HSA-195721
Hh mutants are degraded by ERAD R-HSA-5362768
Programmed Cell Death R-HSA-5357801
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Downstream TCR signaling R-HSA-202424
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Gene expression (Transcription) R-HSA-74160
Neddylation R-HSA-8951664
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Adaptive Immune System R-HSA-1280218
Mitotic G2-G2/M phases R-HSA-453274
Synthesis of DNA R-HSA-69239
Beta-catenin independent WNT signaling R-HSA-3858494
Innate Immune System R-HSA-168249
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK family signaling cascades R-HSA-5683057
Cell Cycle R-HSA-1640170
DNA Replication Pre-Initiation R-HSA-69002
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RAS by GAPs R-HSA-5658442
Activation of NF-kappaB in B cells R-HSA-1169091
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
Metabolism of proteins R-HSA-392499
Metabolism of polyamines R-HSA-351202
Ub-specific processing proteases R-HSA-5689880
Cellular responses to stimuli R-HSA-8953897
Hedgehog ligand biogenesis R-HSA-5358346
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to hypoxia R-HSA-1234174
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Defective CFTR causes cystic fibrosis R-HSA-5678895
DNA Replication R-HSA-69306
Apoptosis R-HSA-109581
Immune System R-HSA-168256
Mitotic G1 phase and G1/S transition R-HSA-453279
S Phase R-HSA-69242
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC-family proteins mediated transport R-HSA-382556
Degradation of GLI2 by the proteasome R-HSA-5610783
Assembly of the pre-replicative complex R-HSA-68867
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of RNA R-HSA-8953854
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S DNA Damage Checkpoints R-HSA-69615
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
p53-Independent DNA Damage Response R-HSA-69610
Metabolism R-HSA-1430728
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
KEAP1-NFE2L2 pathway R-HSA-9755511
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX1 R-HSA-8878171
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX2 R-HSA-8878166
Neutrophil degranulation R-HSA-6798695
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of AXIN R-HSA-4641257
Stabilization of p53 R-HSA-69541
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'on' state R-HSA-5632684
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Asymmetric localization of PCP proteins R-HSA-4608870
Signal Transduction R-HSA-162582
UCH proteinases R-HSA-5689603
G2/M Transition R-HSA-69275
Signaling by Hedgehog R-HSA-5358351
Adaptive Immune System R-HSA-1280218
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of RNA R-HSA-8953854
Nuclear events mediated by NFE2L2 R-HSA-9759194
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
Mitotic Anaphase R-HSA-68882
Neddylation R-HSA-8951664
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
ABC transporter disorders R-HSA-5619084
Beta-catenin independent WNT signaling R-HSA-3858494
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ER-Phagosome pathway R-HSA-1236974
Neutrophil degranulation R-HSA-6798695
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
Degradation of GLI2 by the proteasome R-HSA-5610783
Mitotic G2-G2/M phases R-HSA-453274
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Degradation of DVL R-HSA-4641258
Signaling by WNT R-HSA-195721
Nervous system development R-HSA-9675108
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RAF/MAP kinase cascade R-HSA-5673001
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle Checkpoints R-HSA-69620
DNA Replication R-HSA-69306
p53-Independent DNA Damage Response R-HSA-69610
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of AXIN R-HSA-4641257
Regulation of mitotic cell cycle R-HSA-453276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cytokine Signaling in Immune system R-HSA-1280215
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by Interleukins R-HSA-449147
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of proteins R-HSA-392499
MAPK6/MAPK4 signaling R-HSA-5687128
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Deubiquitination R-HSA-5688426
Metabolism R-HSA-1430728
FCERI mediated NF-kB activation R-HSA-2871837
PIP3 activates AKT signaling R-HSA-1257604
RNA Polymerase II Transcription R-HSA-73857
Stabilization of p53 R-HSA-69541
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
G1/S Transition R-HSA-69206
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hedgehog 'off' state R-HSA-5610787
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle R-HSA-1640170
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Disorders of transmembrane transporters R-HSA-5619115
Post-translational protein modification R-HSA-597592
Metabolism of polyamines R-HSA-351202
Immune System R-HSA-168256
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Synthesis of DNA R-HSA-69239
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
M Phase R-HSA-68886
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Interleukin-1 signaling R-HSA-9020702
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
Activation of NF-kappaB in B cells R-HSA-1169091
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
MAPK family signaling cascades R-HSA-5683057
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing-Cross presentation R-HSA-1236975
Vpu mediated degradation of CD4 R-HSA-180534
Vif-mediated degradation of APOBEC3G R-HSA-180585
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle, Mitotic R-HSA-69278
Gene expression (Transcription) R-HSA-74160
Degradation of beta-catenin by the destruction complex R-HSA-195253
Orc1 removal from chromatin R-HSA-68949
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular responses to stimuli R-HSA-8953897
CLEC7A (Dectin-1) signaling R-HSA-5607764
ABC-family proteins mediated transport R-HSA-382556
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Class I MHC mediated antigen processing & presentation R-HSA-983169
Downstream TCR signaling R-HSA-202424
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
Signaling by ROBO receptors R-HSA-376176
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Infectious disease R-HSA-5663205
Intracellular signaling by second messengers R-HSA-9006925
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ub-specific processing proteases R-HSA-5689880
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of PTEN stability and activity R-HSA-8948751
PCP/CE pathway R-HSA-4086400
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Apoptosis R-HSA-109581
G2/M Checkpoints R-HSA-69481
TCF dependent signaling in response to WNT R-HSA-201681
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of Apoptosis R-HSA-169911
Synthesis of DNA R-HSA-69239
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic G1 phase and G1/S transition R-HSA-453279
Programmed Cell Death R-HSA-5357801
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Ub-specific processing proteases R-HSA-5689880
Axon guidance R-HSA-422475
Mitotic Anaphase R-HSA-68882
Switching of origins to a post-replicative state R-HSA-69052
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK1/MAPK3 signaling R-HSA-5684996
Separation of Sister Chromatids R-HSA-2467813
Generic Transcription Pathway R-HSA-212436
Stabilization of p53 R-HSA-69541
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Hedgehog R-HSA-5358351
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of PTEN stability and activity R-HSA-8948751
Assembly of the pre-replicative complex R-HSA-68867
Apoptosis R-HSA-109581
Cell Cycle R-HSA-1640170
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle, Mitotic R-HSA-69278
S Phase R-HSA-69242
Cellular response to hypoxia R-HSA-1234174
Signaling by Interleukins R-HSA-449147
Neutrophil degranulation R-HSA-6798695
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'off' state R-HSA-5610787
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
ABC transporter disorders R-HSA-5619084
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
G2/M Transition R-HSA-69275
ER-Phagosome pathway R-HSA-1236974
G1/S Transition R-HSA-69206
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of beta-catenin by the destruction complex R-HSA-195253
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular response to chemical stress R-HSA-9711123
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neddylation R-HSA-8951664
DNA Replication Pre-Initiation R-HSA-69002
Interleukin-1 signaling R-HSA-9020702
PCP/CE pathway R-HSA-4086400
ABC-family proteins mediated transport R-HSA-382556
PIP3 activates AKT signaling R-HSA-1257604
PTEN Regulation R-HSA-6807070
Degradation of AXIN R-HSA-4641257
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream TCR signaling R-HSA-202424
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'on' state R-HSA-5632684
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G2/M Checkpoints R-HSA-69481
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX2 R-HSA-8878166
Disorders of transmembrane transporters R-HSA-5619115
UCH proteinases R-HSA-5689603
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Immune System R-HSA-168256
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of RNA R-HSA-8953854
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
Signal Transduction R-HSA-162582
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by NOTCH R-HSA-157118
MAPK6/MAPK4 signaling R-HSA-5687128
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism R-HSA-1430728
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transport of small molecules R-HSA-382551
Metabolism of amino acids and derivatives R-HSA-71291
Post-translational protein modification R-HSA-597592
Orc1 removal from chromatin R-HSA-68949
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by ROBO receptors R-HSA-376176
TCR signaling R-HSA-202403
Degradation of DVL R-HSA-4641258
Signaling by NOTCH4 R-HSA-9013694
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vif-mediated degradation of APOBEC3G R-HSA-180585
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Dependent G1 DNA Damage Response R-HSA-69563
Mitotic G2-G2/M phases R-HSA-453274
Gene expression (Transcription) R-HSA-74160
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
TCF dependent signaling in response to WNT R-HSA-201681
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent DNA Damage Response R-HSA-69610
RAF/MAP kinase cascade R-HSA-5673001
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cell Cycle Checkpoints R-HSA-69620
Metabolism of proteins R-HSA-392499
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hh mutants are degraded by ERAD R-HSA-5362768
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
DNA Replication R-HSA-69306
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Deubiquitination R-HSA-5688426
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
Regulation of Apoptosis R-HSA-169911
Hedgehog ligand biogenesis R-HSA-5358346
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RAS by GAPs R-HSA-5658442
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of polyamines R-HSA-351202
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stress R-HSA-2262752

Expression Atlas ENSG00000173692
NCBI gene (formerly Entrezgene) 5707
GeneCards 9554
HGNC Symbol HGNC:9554
MIM gene 617842
UniProtKB Gene Name Q99460
WikiGene 5707
Gene: PSMA6
Ensembl ID : ENSG00000100902
Description: proteasome 20S subunit alpha 6
Gene Synonyms: IOTA,MGC22756,MGC2333,MGC23846,P27K,PROS27
6 APIs:
275 Possible Orthologues:

Disease R-HSA-1643685
Stabilization of p53 R-HSA-69541
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
Adaptive Immune System R-HSA-1280218
Signaling by ROBO receptors R-HSA-376176
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
Assembly of the pre-replicative complex R-HSA-68867
ABC-family proteins mediated transport R-HSA-382556
Regulation of mitotic cell cycle R-HSA-453276
Nervous system development R-HSA-9675108
PTEN Regulation R-HSA-6807070
Separation of Sister Chromatids R-HSA-2467813
G1/S Transition R-HSA-69206
Downstream TCR signaling R-HSA-202424
DNA Replication Pre-Initiation R-HSA-69002
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
FCERI mediated NF-kB activation R-HSA-2871837
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Generic Transcription Pathway R-HSA-212436
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by WNT R-HSA-195721
PCP/CE pathway R-HSA-4086400
Cell Cycle Checkpoints R-HSA-69620
Vif-mediated degradation of APOBEC3G R-HSA-180585
Infectious disease R-HSA-5663205
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stimuli R-HSA-8953897
Antigen processing-Cross presentation R-HSA-1236975
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of RUNX2 expression and activity R-HSA-8939902
Interleukin-1 signaling R-HSA-9020702
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX3 R-HSA-8878159
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK6/MAPK4 signaling R-HSA-5687128
ER-Phagosome pathway R-HSA-1236974
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Post-translational protein modification R-HSA-597592
DNA Replication R-HSA-69306
RAF/MAP kinase cascade R-HSA-5673001
Degradation of AXIN R-HSA-4641257
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Interleukins R-HSA-449147
MAPK family signaling cascades R-HSA-5683057
Metabolism R-HSA-1430728
Disease R-HSA-1643685
G2/M Transition R-HSA-69275
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Immune System R-HSA-168256
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle, Mitotic R-HSA-69278
Innate Immune System R-HSA-168249
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of RUNX3 expression and activity R-HSA-8941858
Vpu mediated degradation of CD4 R-HSA-180534
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RAS by GAPs R-HSA-5658442
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of Apoptosis R-HSA-169911
Hedgehog 'off' state R-HSA-5610787
Developmental Biology R-HSA-1266738
Synthesis of DNA R-HSA-69239
Programmed Cell Death R-HSA-5357801
Cellular responses to stress R-HSA-2262752
Signaling by Hedgehog R-HSA-5358351
Activation of NF-kappaB in B cells R-HSA-1169091
Ub-specific processing proteases R-HSA-5689880
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic G1 phase and G1/S transition R-HSA-453279
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism of amino acids and derivatives R-HSA-71291
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hh mutants abrogate ligand secretion R-HSA-5387390
Hh mutants are degraded by ERAD R-HSA-5362768
Apoptosis R-HSA-109581
ABC transporter disorders R-HSA-5619084
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of GLI1 by the proteasome R-HSA-5610780
M Phase R-HSA-68886
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of RNA R-HSA-8953854
p53-Independent DNA Damage Response R-HSA-69610
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Checkpoints R-HSA-69481
Metabolism of polyamines R-HSA-351202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
Transport of small molecules R-HSA-382551
HIV Infection R-HSA-162906
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
TCF dependent signaling in response to WNT R-HSA-201681
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic Anaphase R-HSA-68882
TCR signaling R-HSA-202403
Interleukin-1 family signaling R-HSA-446652
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to chemical stress R-HSA-9711123
Cell Cycle R-HSA-1640170
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
p53-Dependent G1 DNA Damage Response R-HSA-69563
Deubiquitination R-HSA-5688426
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH4 R-HSA-9013694
Regulation of PTEN stability and activity R-HSA-8948751
Disorders of transmembrane transporters R-HSA-5619115
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of proteins R-HSA-392499
Hedgehog 'on' state R-HSA-5632684
Orc1 removal from chromatin R-HSA-68949
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by NOTCH R-HSA-157118
UCH proteinases R-HSA-5689603
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic G1 phase and G1/S transition R-HSA-453279
Nervous system development R-HSA-9675108
DNA Replication Pre-Initiation R-HSA-69002
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
DNA Replication R-HSA-69306
Hh mutants are degraded by ERAD R-HSA-5362768
Interleukin-1 family signaling R-HSA-446652
Cytokine Signaling in Immune system R-HSA-1280215
G1/S Transition R-HSA-69206
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular response to hypoxia R-HSA-1234174
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of proteins R-HSA-392499
Synthesis of DNA R-HSA-69239
Mitotic Metaphase and Anaphase R-HSA-2555396
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog 'off' state R-HSA-5610787
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of DVL R-HSA-4641258
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle, Mitotic R-HSA-69278
Metabolism R-HSA-1430728
Post-translational protein modification R-HSA-597592
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of PTEN stability and activity R-HSA-8948751
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1 DNA Damage Response R-HSA-69563
Asymmetric localization of PCP proteins R-HSA-4608870
Adaptive Immune System R-HSA-1280218
Generic Transcription Pathway R-HSA-212436
Signaling by Interleukins R-HSA-449147
Hedgehog 'on' state R-HSA-5632684
Downstream TCR signaling R-HSA-202424
HIV Infection R-HSA-162906
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of polyamines R-HSA-351202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular response to chemical stress R-HSA-9711123
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of mitotic cell cycle R-HSA-453276
Vpu mediated degradation of CD4 R-HSA-180534
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
RAF/MAP kinase cascade R-HSA-5673001
Transport of small molecules R-HSA-382551
Intracellular signaling by second messengers R-HSA-9006925
MAPK family signaling cascades R-HSA-5683057
Immune System R-HSA-168256
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Gene expression (Transcription) R-HSA-74160
PCP/CE pathway R-HSA-4086400
Cellular responses to stimuli R-HSA-8953897
Cyclin E associated events during G1/S transition R-HSA-69202
TCF dependent signaling in response to WNT R-HSA-201681
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RUNX2 expression and activity R-HSA-8939902
Disease R-HSA-1643685
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of GLI2 by the proteasome R-HSA-5610783
Axon guidance R-HSA-422475
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by ROBO receptors R-HSA-376176
Cell Cycle R-HSA-1640170
Programmed Cell Death R-HSA-5357801
Nuclear events mediated by NFE2L2 R-HSA-9759194
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of AXIN R-HSA-4641257
Transcriptional regulation by RUNX2 R-HSA-8878166
Vif-mediated degradation of APOBEC3G R-HSA-180585
M Phase R-HSA-68886
Orc1 removal from chromatin R-HSA-68949
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TCR signaling R-HSA-202403
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH4 R-HSA-9013694
ABC-family proteins mediated transport R-HSA-382556
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
ABC transporter disorders R-HSA-5619084
Defective CFTR causes cystic fibrosis R-HSA-5678895
Assembly of the pre-replicative complex R-HSA-68867
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX3 expression and activity R-HSA-8941858
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Developmental Biology R-HSA-1266738
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX3 R-HSA-8878159
Stabilization of p53 R-HSA-69541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of beta-catenin by the destruction complex R-HSA-195253
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RNA Polymerase II Transcription R-HSA-73857
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH R-HSA-157118
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signal Transduction R-HSA-162582
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
Deubiquitination R-HSA-5688426
G2/M Checkpoints R-HSA-69481
Cellular responses to stress R-HSA-2262752
Separation of Sister Chromatids R-HSA-2467813
Mitotic G2-G2/M phases R-HSA-453274
Regulation of Apoptosis R-HSA-169911
Disorders of transmembrane transporters R-HSA-5619115
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
Signaling by Hedgehog R-HSA-5358351
ER-Phagosome pathway R-HSA-1236974
PIP3 activates AKT signaling R-HSA-1257604
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PTEN Regulation R-HSA-6807070
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism of RNA R-HSA-8953854
KEAP1-NFE2L2 pathway R-HSA-9755511
Apoptosis R-HSA-109581
Cell Cycle Checkpoints R-HSA-69620
FCERI mediated NF-kB activation R-HSA-2871837
S Phase R-HSA-69242
Innate Immune System R-HSA-168249
UCH proteinases R-HSA-5689603
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
S Phase R-HSA-69242
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Interleukins R-HSA-449147
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle Checkpoints R-HSA-69620
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cellular response to chemical stress R-HSA-9711123
Degradation of beta-catenin by the destruction complex R-HSA-195253
Apoptosis R-HSA-109581
Cell Cycle R-HSA-1640170
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Metabolism of proteins R-HSA-392499
Signaling by Hedgehog R-HSA-5358351
M Phase R-HSA-68886
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RAF/MAP kinase cascade R-HSA-5673001
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX2 R-HSA-8878166
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stimuli R-HSA-8953897
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
DNA Replication R-HSA-69306
Disorders of transmembrane transporters R-HSA-5619115
Transcriptional regulation by RUNX3 R-HSA-8878159
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of polyamines R-HSA-351202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PTEN Regulation R-HSA-6807070
Regulation of mitotic cell cycle R-HSA-453276
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
HIV Infection R-HSA-162906
TCR signaling R-HSA-202403
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of AXIN R-HSA-4641257
Cellular response to hypoxia R-HSA-1234174
Regulation of RUNX3 expression and activity R-HSA-8941858
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Adaptive Immune System R-HSA-1280218
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI1 by the proteasome R-HSA-5610780
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of amino acids and derivatives R-HSA-71291
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Checkpoints R-HSA-69481
Hh mutants are degraded by ERAD R-HSA-5362768
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH4 R-HSA-9013694
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Programmed Cell Death R-HSA-5357801
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
KEAP1-NFE2L2 pathway R-HSA-9755511
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Mitotic Anaphase R-HSA-68882
Regulation of Apoptosis R-HSA-169911
Hedgehog 'on' state R-HSA-5632684
Antigen processing-Cross presentation R-HSA-1236975
G2/M Transition R-HSA-69275
Orc1 removal from chromatin R-HSA-68949
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G1/S Transition R-HSA-69206
Gene expression (Transcription) R-HSA-74160
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of GLI2 by the proteasome R-HSA-5610783
MAPK family signaling cascades R-HSA-5683057
Post-translational protein modification R-HSA-597592
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
Cellular responses to stress R-HSA-2262752
Ub-specific processing proteases R-HSA-5689880
Metabolism of RNA R-HSA-8953854
p53-Independent DNA Damage Response R-HSA-69610
Synthesis of DNA R-HSA-69239
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic Metaphase and Anaphase R-HSA-2555396
Axon guidance R-HSA-422475
Hedgehog 'off' state R-HSA-5610787
DNA Replication Pre-Initiation R-HSA-69002
Metabolism R-HSA-1430728
Vif-mediated degradation of APOBEC3G R-HSA-180585
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 family signaling R-HSA-446652
Mitotic G2-G2/M phases R-HSA-453274
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle, Mitotic R-HSA-69278
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Intracellular signaling by second messengers R-HSA-9006925
Transport of small molecules R-HSA-382551
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Deubiquitination R-HSA-5688426
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional regulation by RUNX1 R-HSA-8878171
Signal Transduction R-HSA-162582
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of NF-kappaB in B cells R-HSA-1169091
Negative regulation of NOTCH4 signaling R-HSA-9604323
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 signaling R-HSA-9020702
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ABC transporter disorders R-HSA-5619084
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH R-HSA-157118
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Hedgehog ligand biogenesis R-HSA-5358346
Separation of Sister Chromatids R-HSA-2467813
Degradation of DVL R-HSA-4641258
Regulation of RUNX2 expression and activity R-HSA-8939902
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream TCR signaling R-HSA-202424
PCP/CE pathway R-HSA-4086400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
Host Interactions of HIV factors R-HSA-162909
Signaling by WNT R-HSA-195721
Cyclin E associated events during G1/S transition R-HSA-69202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hh mutants abrogate ligand secretion R-HSA-5387390
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
M Phase R-HSA-68886
Metabolism R-HSA-1430728
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stress R-HSA-2262752
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'on' state R-HSA-5632684
DNA Replication R-HSA-69306
Synthesis of DNA R-HSA-69239
p53-Dependent G1 DNA Damage Response R-HSA-69563
CLEC7A (Dectin-1) signaling R-HSA-5607764
Stabilization of p53 R-HSA-69541
Assembly of the pre-replicative complex R-HSA-68867
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to hypoxia R-HSA-1234174
Cell Cycle R-HSA-1640170
ER-Phagosome pathway R-HSA-1236974
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
Hh mutants abrogate ligand secretion R-HSA-5387390
Disorders of transmembrane transporters R-HSA-5619115
Post-translational protein modification R-HSA-597592
Cyclin E associated events during G1/S transition R-HSA-69202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Adaptive Immune System R-HSA-1280218
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hedgehog ligand biogenesis R-HSA-5358346
TCF dependent signaling in response to WNT R-HSA-201681
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
Downstream TCR signaling R-HSA-202424
p53-Independent DNA Damage Response R-HSA-69610
Mitotic G2-G2/M phases R-HSA-453274
Degradation of beta-catenin by the destruction complex R-HSA-195253
Beta-catenin independent WNT signaling R-HSA-3858494
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of DVL R-HSA-4641258
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Asymmetric localization of PCP proteins R-HSA-4608870
Generic Transcription Pathway R-HSA-212436
ABC-family proteins mediated transport R-HSA-382556
Switching of origins to a post-replicative state R-HSA-69052
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
UCH proteinases R-HSA-5689603
Signaling by NOTCH4 R-HSA-9013694
Activation of NF-kappaB in B cells R-HSA-1169091
Developmental Biology R-HSA-1266738
Signaling by ROBO receptors R-HSA-376176
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G1 phase and G1/S transition R-HSA-453279
Interleukin-1 family signaling R-HSA-446652
Metabolism of proteins R-HSA-392499
Neddylation R-HSA-8951664
Cell Cycle, Mitotic R-HSA-69278
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants are degraded by ERAD R-HSA-5362768
PIP3 activates AKT signaling R-HSA-1257604
Programmed Cell Death R-HSA-5357801
HIV Infection R-HSA-162906
Axon guidance R-HSA-422475
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog 'off' state R-HSA-5610787
Signaling by WNT R-HSA-195721
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Deubiquitination R-HSA-5688426
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by Hedgehog R-HSA-5358351
RAF/MAP kinase cascade R-HSA-5673001
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Ub-specific processing proteases R-HSA-5689880
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Separation of Sister Chromatids R-HSA-2467813
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G1/S Transition R-HSA-69206
Metabolism of RNA R-HSA-8953854
Transport of small molecules R-HSA-382551
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
TCR signaling R-HSA-202403
Cellular responses to stimuli R-HSA-8953897
Mitotic Metaphase and Anaphase R-HSA-2555396
PTEN Regulation R-HSA-6807070
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G2/M Transition R-HSA-69275
Antigen processing-Cross presentation R-HSA-1236975
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
G2/M Checkpoints R-HSA-69481
Cellular response to chemical stress R-HSA-9711123
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Defective CFTR causes cystic fibrosis R-HSA-5678895
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX1 R-HSA-8878171
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of polyamines R-HSA-351202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of RAS by GAPs R-HSA-5658442
Disease R-HSA-1643685
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mitotic cell cycle R-HSA-453276
FCERI mediated NF-kB activation R-HSA-2871837
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of amino acids and derivatives R-HSA-71291
MAPK family signaling cascades R-HSA-5683057
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX2 R-HSA-8878166
Host Interactions of HIV factors R-HSA-162909
ABC transporter disorders R-HSA-5619084
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Class I MHC mediated antigen processing & presentation R-HSA-983169
Orc1 removal from chromatin R-HSA-68949
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Negative regulation of NOTCH4 signaling R-HSA-9604323
Mitotic Anaphase R-HSA-68882
Signaling by Interleukins R-HSA-449147
C-type lectin receptors (CLRs) R-HSA-5621481
Gene expression (Transcription) R-HSA-74160
Apoptosis R-HSA-109581
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK1/MAPK3 signaling R-HSA-5684996
RNA Polymerase II Transcription R-HSA-73857
Mitotic G1 phase and G1/S transition R-HSA-453279
Neddylation R-HSA-8951664
TCR signaling R-HSA-202403
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
ER-Phagosome pathway R-HSA-1236974
G2/M Transition R-HSA-69275
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PCP/CE pathway R-HSA-4086400
Degradation of AXIN R-HSA-4641257
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'on' state R-HSA-5632684
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transcriptional regulation by RUNX3 R-HSA-8878159
p53-Independent DNA Damage Response R-HSA-69610
Activation of NF-kappaB in B cells R-HSA-1169091
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Hedgehog R-HSA-5358351
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of mitotic cell cycle R-HSA-453276
Downstream TCR signaling R-HSA-202424
Beta-catenin independent WNT signaling R-HSA-3858494
Nervous system development R-HSA-9675108
MAPK6/MAPK4 signaling R-HSA-5687128
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of polyamines R-HSA-351202
Signaling by NOTCH R-HSA-157118
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
Separation of Sister Chromatids R-HSA-2467813
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Antigen processing-Cross presentation R-HSA-1236975
Orc1 removal from chromatin R-HSA-68949
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by ROBO receptors R-HSA-376176
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
Class I MHC mediated antigen processing & presentation R-HSA-983169
ABC-family proteins mediated transport R-HSA-382556
S Phase R-HSA-69242
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PIP3 activates AKT signaling R-HSA-1257604
Hh mutants abrogate ligand secretion R-HSA-5387390
Switching of origins to a post-replicative state R-HSA-69052
G1/S DNA Damage Checkpoints R-HSA-69615
Assembly of the pre-replicative complex R-HSA-68867
Stabilization of p53 R-HSA-69541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Infectious disease R-HSA-5663205
ABC transporter disorders R-HSA-5619084
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI2 by the proteasome R-HSA-5610783
RNA Polymerase II Transcription R-HSA-73857
Regulation of RAS by GAPs R-HSA-5658442
Cellular response to hypoxia R-HSA-1234174
Signal Transduction R-HSA-162582
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by WNT R-HSA-195721
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic G2-G2/M phases R-HSA-453274
Regulation of PTEN stability and activity R-HSA-8948751
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of RUNX2 expression and activity R-HSA-8939902
Developmental Biology R-HSA-1266738
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
Cell Cycle, Mitotic R-HSA-69278
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
Transport of small molecules R-HSA-382551
RAF/MAP kinase cascade R-HSA-5673001
G2/M Checkpoints R-HSA-69481
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX2 R-HSA-8878166
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of proteins R-HSA-392499
Interleukin-1 signaling R-HSA-9020702
Vif-mediated degradation of APOBEC3G R-HSA-180585
HIV Infection R-HSA-162906
Degradation of GLI1 by the proteasome R-HSA-5610780
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Host Interactions of HIV factors R-HSA-162909
Deubiquitination R-HSA-5688426
G1/S Transition R-HSA-69206
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of RNA R-HSA-8953854
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hedgehog 'off' state R-HSA-5610787
Programmed Cell Death R-HSA-5357801
UCH proteinases R-HSA-5689603
Synthesis of DNA R-HSA-69239
Hedgehog ligand biogenesis R-HSA-5358346
p53-Dependent G1 DNA Damage Response R-HSA-69563
Post-translational protein modification R-HSA-597592
Immune System R-HSA-168256
Apoptosis R-HSA-109581
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of amino acids and derivatives R-HSA-71291
Cytokine Signaling in Immune system R-HSA-1280215
DNA Replication R-HSA-69306
PTEN Regulation R-HSA-6807070
Cellular response to chemical stress R-HSA-9711123
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stress R-HSA-2262752
Regulation of RUNX3 expression and activity R-HSA-8941858
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
M Phase R-HSA-68886
Signaling by NOTCH4 R-HSA-9013694
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK family signaling cascades R-HSA-5683057
Disorders of transmembrane transporters R-HSA-5619115
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Stabilization of p53 R-HSA-69541
Hh mutants are degraded by ERAD R-HSA-5362768
G1/S Transition R-HSA-69206
Programmed Cell Death R-HSA-5357801
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mitotic cell cycle R-HSA-453276
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent DNA Damage Response R-HSA-69610
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
DNA Replication R-HSA-69306
Infectious disease R-HSA-5663205
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stimuli R-HSA-8953897
Transport of small molecules R-HSA-382551
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
Regulation of RUNX3 expression and activity R-HSA-8941858
Synthesis of DNA R-HSA-69239
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of Apoptosis R-HSA-169911
Deubiquitination R-HSA-5688426
Switching of origins to a post-replicative state R-HSA-69052
Signaling by Interleukins R-HSA-449147
Signaling by NOTCH R-HSA-157118
MAPK family signaling cascades R-HSA-5683057
G1/S DNA Damage Checkpoints R-HSA-69615
RAF/MAP kinase cascade R-HSA-5673001
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular responses to stress R-HSA-2262752
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin E associated events during G1/S transition R-HSA-69202
Developmental Biology R-HSA-1266738
Downstream TCR signaling R-HSA-202424
M Phase R-HSA-68886
Mitotic G1 phase and G1/S transition R-HSA-453279
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nuclear events mediated by NFE2L2 R-HSA-9759194
RNA Polymerase II Transcription R-HSA-73857
Degradation of AXIN R-HSA-4641257
Degradation of GLI2 by the proteasome R-HSA-5610783
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Vpu mediated degradation of CD4 R-HSA-180534
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Hh mutants abrogate ligand secretion R-HSA-5387390
Cellular response to hypoxia R-HSA-1234174
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
S Phase R-HSA-69242
Mitotic G2-G2/M phases R-HSA-453274
Metabolism of RNA R-HSA-8953854
Degradation of beta-catenin by the destruction complex R-HSA-195253
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Host Interactions of HIV factors R-HSA-162909
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Disorders of transmembrane transporters R-HSA-5619115
Defective CFTR causes cystic fibrosis R-HSA-5678895
PCP/CE pathway R-HSA-4086400
G2/M Transition R-HSA-69275
Negative regulation of NOTCH4 signaling R-HSA-9604323
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
HIV Infection R-HSA-162906
Gene expression (Transcription) R-HSA-74160
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hedgehog 'on' state R-HSA-5632684
Metabolism of polyamines R-HSA-351202
Signal Transduction R-HSA-162582
Interleukin-1 signaling R-HSA-9020702
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic Metaphase and Anaphase R-HSA-2555396
DNA Replication Pre-Initiation R-HSA-69002
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Apoptosis R-HSA-109581
Hedgehog 'off' state R-HSA-5610787
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Ub-specific processing proteases R-HSA-5689880
Signaling by WNT R-HSA-195721
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH4 R-HSA-9013694
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Post-translational protein modification R-HSA-597592
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of DVL R-HSA-4641258
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
Cellular response to chemical stress R-HSA-9711123
Neddylation R-HSA-8951664
KEAP1-NFE2L2 pathway R-HSA-9755511
TCR signaling R-HSA-202403
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic Anaphase R-HSA-68882
MAPK1/MAPK3 signaling R-HSA-5684996
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 family signaling R-HSA-446652
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Immune System R-HSA-168256
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Antigen processing-Cross presentation R-HSA-1236975
ABC transporter disorders R-HSA-5619084
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Adaptive Immune System R-HSA-1280218
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Generic Transcription Pathway R-HSA-212436
Innate Immune System R-HSA-168249
Assembly of the pre-replicative complex R-HSA-68867
Class I MHC mediated antigen processing & presentation R-HSA-983169
Nervous system development R-HSA-9675108
Intracellular signaling by second messengers R-HSA-9006925
Vif-mediated degradation of APOBEC3G R-HSA-180585
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of amino acids and derivatives R-HSA-71291
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Axon guidance R-HSA-422475
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of proteins R-HSA-392499
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle R-HSA-1640170
G2/M Checkpoints R-HSA-69481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by WNT R-HSA-195721
Signaling by NOTCH R-HSA-157118
Regulation of RUNX2 expression and activity R-HSA-8939902
Developmental Biology R-HSA-1266738
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G1 phase and G1/S transition R-HSA-453279
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular responses to stimuli R-HSA-8953897
Cyclin E associated events during G1/S transition R-HSA-69202
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PCP/CE pathway R-HSA-4086400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream TCR signaling R-HSA-202424
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
RAF/MAP kinase cascade R-HSA-5673001
ABC-family proteins mediated transport R-HSA-382556
Degradation of GLI1 by the proteasome R-HSA-5610780
Orc1 removal from chromatin R-HSA-68949
TCR signaling R-HSA-202403
Cell Cycle, Mitotic R-HSA-69278
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
PIP3 activates AKT signaling R-HSA-1257604
HIV Infection R-HSA-162906
Hedgehog 'off' state R-HSA-5610787
Cell Cycle Checkpoints R-HSA-69620
ABC transporter disorders R-HSA-5619084
Metabolism of RNA R-HSA-8953854
Deubiquitination R-HSA-5688426
Infectious disease R-HSA-5663205
Ub-specific processing proteases R-HSA-5689880
Mitotic Metaphase and Anaphase R-HSA-2555396
Disorders of transmembrane transporters R-HSA-5619115
Stabilization of p53 R-HSA-69541
Mitotic G2-G2/M phases R-HSA-453274
Separation of Sister Chromatids R-HSA-2467813
Adaptive Immune System R-HSA-1280218
Hh mutants abrogate ligand secretion R-HSA-5387390
Transcriptional regulation by RUNX2 R-HSA-8878166
Generic Transcription Pathway R-HSA-212436
Mitotic Anaphase R-HSA-68882
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Host Interactions of HIV factors R-HSA-162909
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of beta-catenin by the destruction complex R-HSA-195253
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Dependent G1 DNA Damage Response R-HSA-69563
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog 'on' state R-HSA-5632684
Cytokine Signaling in Immune system R-HSA-1280215
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by Hedgehog R-HSA-5358351
MAPK family signaling cascades R-HSA-5683057
ER-Phagosome pathway R-HSA-1236974
Assembly of the pre-replicative complex R-HSA-68867
UCH proteinases R-HSA-5689603
G2/M Checkpoints R-HSA-69481
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of polyamines R-HSA-351202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Neddylation R-HSA-8951664
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX3 expression and activity R-HSA-8941858
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by NOTCH4 R-HSA-9013694
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
RNA Polymerase II Transcription R-HSA-73857
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of DVL R-HSA-4641258
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of amino acids and derivatives R-HSA-71291
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to chemical stress R-HSA-9711123
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hedgehog ligand biogenesis R-HSA-5358346
Activation of NF-kappaB in B cells R-HSA-1169091
Nervous system development R-HSA-9675108
Defective CFTR causes cystic fibrosis R-HSA-5678895
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G2/M Transition R-HSA-69275
G1/S Transition R-HSA-69206
Regulation of Apoptosis R-HSA-169911
Axon guidance R-HSA-422475
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Interleukin-1 signaling R-HSA-9020702
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RAS by GAPs R-HSA-5658442
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism R-HSA-1430728
Signal Transduction R-HSA-162582
Signaling by the B Cell Receptor (BCR) R-HSA-983705
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
Signaling by ROBO receptors R-HSA-376176
Synthesis of DNA R-HSA-69239
NIK-->noncanonical NF-kB signaling R-HSA-5676590
M Phase R-HSA-68886
Cell Cycle R-HSA-1640170
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of mitotic cell cycle R-HSA-453276
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Class I MHC mediated antigen processing & presentation R-HSA-983169
Transport of small molecules R-HSA-382551
Intracellular signaling by second messengers R-HSA-9006925
Cellular response to hypoxia R-HSA-1234174
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Signaling by Interleukins R-HSA-449147
Programmed Cell Death R-HSA-5357801
Asymmetric localization of PCP proteins R-HSA-4608870
Post-translational protein modification R-HSA-597592
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX3 R-HSA-8878159
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of AXIN R-HSA-4641257
Separation of Sister Chromatids R-HSA-2467813
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to chemical stress R-HSA-9711123
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-1 family signaling R-HSA-446652
Orc1 removal from chromatin R-HSA-68949
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of DVL R-HSA-4641258
TCR signaling R-HSA-202403
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of RUNX2 expression and activity R-HSA-8939902
Apoptosis R-HSA-109581
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of Apoptosis R-HSA-169911
Class I MHC mediated antigen processing & presentation R-HSA-983169
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
Regulation of PTEN stability and activity R-HSA-8948751
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Anaphase R-HSA-68882
Cytokine Signaling in Immune system R-HSA-1280215
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
PCP/CE pathway R-HSA-4086400
Host Interactions of HIV factors R-HSA-162909
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S DNA Damage Checkpoints R-HSA-69615
Switching of origins to a post-replicative state R-HSA-69052
G2/M Transition R-HSA-69275
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RNA Polymerase II Transcription R-HSA-73857
Metabolism of polyamines R-HSA-351202
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK family signaling cascades R-HSA-5683057
G1/S Transition R-HSA-69206
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent DNA Damage Response R-HSA-69610
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
Hedgehog 'off' state R-HSA-5610787
PTEN Regulation R-HSA-6807070
Disease R-HSA-1643685
Metabolism of amino acids and derivatives R-HSA-71291
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G2-G2/M phases R-HSA-453274
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of mitotic cell cycle R-HSA-453276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC-family proteins mediated transport R-HSA-382556
Generic Transcription Pathway R-HSA-212436
Intracellular signaling by second messengers R-HSA-9006925
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK6/MAPK4 signaling R-HSA-5687128
Cell Cycle, Mitotic R-HSA-69278
Post-translational protein modification R-HSA-597592
Cyclin E associated events during G1/S transition R-HSA-69202
Programmed Cell Death R-HSA-5357801
S Phase R-HSA-69242
ABC transporter disorders R-HSA-5619084
G2/M Checkpoints R-HSA-69481
Signaling by ROBO receptors R-HSA-376176
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX2 R-HSA-8878166
Asymmetric localization of PCP proteins R-HSA-4608870
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RAS by GAPs R-HSA-5658442
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI2 by the proteasome R-HSA-5610783
HIV Infection R-HSA-162906
Signaling by NOTCH4 R-HSA-9013694
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stress R-HSA-2262752
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Downstream TCR signaling R-HSA-202424
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular response to hypoxia R-HSA-1234174
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Innate Immune System R-HSA-168249
Metabolism R-HSA-1430728
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Infectious disease R-HSA-5663205
Stabilization of p53 R-HSA-69541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of RNA R-HSA-8953854
Metabolism of proteins R-HSA-392499
C-type lectin receptors (CLRs) R-HSA-5621481
M Phase R-HSA-68886
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signal Transduction R-HSA-162582
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle R-HSA-1640170
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stimuli R-HSA-8953897
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ub-specific processing proteases R-HSA-5689880
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Developmental Biology R-HSA-1266738
Synthesis of DNA R-HSA-69239
Signaling by WNT R-HSA-195721
ER-Phagosome pathway R-HSA-1236974
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Adaptive Immune System R-HSA-1280218
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Interleukins R-HSA-449147
Vif-mediated degradation of APOBEC3G R-HSA-180585
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Interleukin-1 signaling R-HSA-9020702
Assembly of the pre-replicative complex R-HSA-68867
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Immune System R-HSA-168256
Transport of small molecules R-HSA-382551
Hedgehog 'on' state R-HSA-5632684
Nervous system development R-HSA-9675108
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by NOTCH4 R-HSA-9013694
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of AXIN R-HSA-4641257
Host Interactions of HIV factors R-HSA-162909
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
M Phase R-HSA-68886
Switching of origins to a post-replicative state R-HSA-69052
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of GLI1 by the proteasome R-HSA-5610780
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Disorders of transmembrane transporters R-HSA-5619115
Regulation of RUNX3 expression and activity R-HSA-8941858
Antigen processing-Cross presentation R-HSA-1236975
MAPK6/MAPK4 signaling R-HSA-5687128
Stabilization of p53 R-HSA-69541
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'on' state R-HSA-5632684
Programmed Cell Death R-HSA-5357801
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by Hedgehog R-HSA-5358351
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of RNA R-HSA-8953854
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Apoptosis R-HSA-109581
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by ROBO receptors R-HSA-376176
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic G1 phase and G1/S transition R-HSA-453279
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
HIV Infection R-HSA-162906
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent DNA Damage Response R-HSA-69610
RAF/MAP kinase cascade R-HSA-5673001
Post-translational protein modification R-HSA-597592
Orc1 removal from chromatin R-HSA-68949
Cell Cycle Checkpoints R-HSA-69620
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Separation of Sister Chromatids R-HSA-2467813
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of NF-kappaB in B cells R-HSA-1169091
S Phase R-HSA-69242
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Synthesis of DNA R-HSA-69239
Immune System R-HSA-168256
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
UCH proteinases R-HSA-5689603
Metabolism of polyamines R-HSA-351202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transport of small molecules R-HSA-382551
Metabolism R-HSA-1430728
ABC-family proteins mediated transport R-HSA-382556
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
G2/M Transition R-HSA-69275
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
FCERI mediated NF-kB activation R-HSA-2871837
Cellular response to hypoxia R-HSA-1234174
KEAP1-NFE2L2 pathway R-HSA-9755511
Deubiquitination R-HSA-5688426
Intracellular signaling by second messengers R-HSA-9006925
Signaling by NOTCH R-HSA-157118
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
PCP/CE pathway R-HSA-4086400
Signaling by Interleukins R-HSA-449147
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle, Mitotic R-HSA-69278
Asymmetric localization of PCP proteins R-HSA-4608870
Gene expression (Transcription) R-HSA-74160
Hedgehog 'off' state R-HSA-5610787
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
p53-Dependent G1 DNA Damage Response R-HSA-69563
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Class I MHC mediated antigen processing & presentation R-HSA-983169
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Generic Transcription Pathway R-HSA-212436
DNA Replication R-HSA-69306
Regulation of Apoptosis R-HSA-169911
Ub-specific processing proteases R-HSA-5689880
Mitotic Metaphase and Anaphase R-HSA-2555396
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of DVL R-HSA-4641258
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX1 R-HSA-8878171
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Developmental Biology R-HSA-1266738
Signaling by WNT R-HSA-195721
ABC transporter disorders R-HSA-5619084
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cell Cycle R-HSA-1640170
Regulation of RUNX2 expression and activity R-HSA-8939902
TCR signaling R-HSA-202403
Regulation of PTEN stability and activity R-HSA-8948751
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Beta-catenin independent WNT signaling R-HSA-3858494
ER-Phagosome pathway R-HSA-1236974
Cellular responses to stimuli R-HSA-8953897
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transcriptional regulation by RUNX2 R-HSA-8878166
Assembly of the pre-replicative complex R-HSA-68867
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of mitotic cell cycle R-HSA-453276
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G1/S DNA Damage Checkpoints R-HSA-69615
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic Anaphase R-HSA-68882
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of amino acids and derivatives R-HSA-71291
TCF dependent signaling in response to WNT R-HSA-201681
Infectious disease R-HSA-5663205
Downstream TCR signaling R-HSA-202424
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 signaling R-HSA-9020702
Neddylation R-HSA-8951664
Adaptive Immune System R-HSA-1280218
Cyclin E associated events during G1/S transition R-HSA-69202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
Interleukin-1 family signaling R-HSA-446652
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RAS by GAPs R-HSA-5658442
Mitotic G2-G2/M phases R-HSA-453274
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Post-translational protein modification R-HSA-597592
Apoptosis R-HSA-109581
PIP3 activates AKT signaling R-HSA-1257604
ER-Phagosome pathway R-HSA-1236974
Ub-specific processing proteases R-HSA-5689880
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Hedgehog R-HSA-5358351
Neddylation R-HSA-8951664
Signaling by NOTCH4 R-HSA-9013694
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX2 expression and activity R-HSA-8939902
Separation of Sister Chromatids R-HSA-2467813
Metabolism of proteins R-HSA-392499
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G2/M Checkpoints R-HSA-69481
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI2 by the proteasome R-HSA-5610783
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
Regulation of Apoptosis R-HSA-169911
Degradation of DVL R-HSA-4641258
Class I MHC mediated antigen processing & presentation R-HSA-983169
PCP/CE pathway R-HSA-4086400
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of GLI1 by the proteasome R-HSA-5610780
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Transition R-HSA-69275
Signal Transduction R-HSA-162582
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Generic Transcription Pathway R-HSA-212436
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stimuli R-HSA-8953897
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'off' state R-HSA-5610787
Hh mutants abrogate ligand secretion R-HSA-5387390
G1/S Transition R-HSA-69206
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism R-HSA-1430728
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle Checkpoints R-HSA-69620
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by WNT R-HSA-195721
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
TCR signaling R-HSA-202403
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 family signaling R-HSA-446652
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Metaphase and Anaphase R-HSA-2555396
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic G1 phase and G1/S transition R-HSA-453279
Antigen processing-Cross presentation R-HSA-1236975
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
KEAP1-NFE2L2 pathway R-HSA-9755511
ABC transporter disorders R-HSA-5619084
Regulation of RAS by GAPs R-HSA-5658442
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Axon guidance R-HSA-422475
Programmed Cell Death R-HSA-5357801
C-type lectin receptors (CLRs) R-HSA-5621481
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH R-HSA-157118
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Assembly of the pre-replicative complex R-HSA-68867
Nuclear events mediated by NFE2L2 R-HSA-9759194
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Downstream TCR signaling R-HSA-202424
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FCERI mediated NF-kB activation R-HSA-2871837
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of RUNX3 expression and activity R-HSA-8941858
Deubiquitination R-HSA-5688426
Regulation of PTEN stability and activity R-HSA-8948751
HIV Infection R-HSA-162906
Intracellular signaling by second messengers R-HSA-9006925
G1/S DNA Damage Checkpoints R-HSA-69615
Stabilization of p53 R-HSA-69541
Immune System R-HSA-168256
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular responses to stress R-HSA-2262752
Metabolism of amino acids and derivatives R-HSA-71291
Switching of origins to a post-replicative state R-HSA-69052
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Metabolism of polyamines R-HSA-351202
Hh mutants are degraded by ERAD R-HSA-5362768
UCH proteinases R-HSA-5689603
PTEN Regulation R-HSA-6807070
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of NOTCH4 signaling R-HSA-9604323
Developmental Biology R-HSA-1266738
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of AXIN R-HSA-4641257
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Interleukins R-HSA-449147
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Infectious disease R-HSA-5663205
Hedgehog 'on' state R-HSA-5632684
Disorders of transmembrane transporters R-HSA-5619115
Cellular response to chemical stress R-HSA-9711123
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle, Mitotic R-HSA-69278
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular response to hypoxia R-HSA-1234174
Synthesis of DNA R-HSA-69239
Transport of small molecules R-HSA-382551
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Innate Immune System R-HSA-168249
p53-Independent DNA Damage Response R-HSA-69610
Mitotic Anaphase R-HSA-68882
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Disease R-HSA-1643685
MAPK1/MAPK3 signaling R-HSA-5684996
Stabilization of p53 R-HSA-69541
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle Checkpoints R-HSA-69620
Post-translational protein modification R-HSA-597592
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cell Cycle R-HSA-1640170
S Phase R-HSA-69242
PCP/CE pathway R-HSA-4086400
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX3 R-HSA-8878159
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Interleukin-1 family signaling R-HSA-446652
Antigen processing-Cross presentation R-HSA-1236975
Regulation of Apoptosis R-HSA-169911
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Orc1 removal from chromatin R-HSA-68949
Hh mutants are degraded by ERAD R-HSA-5362768
Programmed Cell Death R-HSA-5357801
Infectious disease R-HSA-5663205
Apoptosis R-HSA-109581
Hedgehog 'on' state R-HSA-5632684
Signaling by NOTCH R-HSA-157118
Degradation of GLI2 by the proteasome R-HSA-5610783
Downstream TCR signaling R-HSA-202424
Regulation of expression of SLITs and ROBOs R-HSA-9010553
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by Interleukins R-HSA-449147
ER-Phagosome pathway R-HSA-1236974
Degradation of AXIN R-HSA-4641257
Metabolism of amino acids and derivatives R-HSA-71291
p53-Independent DNA Damage Response R-HSA-69610
Mitotic Anaphase R-HSA-68882
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of PTEN stability and activity R-HSA-8948751
RNA Polymerase II Transcription R-HSA-73857
G2/M Transition R-HSA-69275
PTEN Regulation R-HSA-6807070
Signaling by ROBO receptors R-HSA-376176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
TCF dependent signaling in response to WNT R-HSA-201681
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular responses to stimuli R-HSA-8953897
Beta-catenin independent WNT signaling R-HSA-3858494
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Immune System R-HSA-168256
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Interleukin-1 signaling R-HSA-9020702
Signaling by WNT R-HSA-195721
Degradation of DVL R-HSA-4641258
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
Host Interactions of HIV factors R-HSA-162909
Cellular response to chemical stress R-HSA-9711123
CLEC7A (Dectin-1) signaling R-HSA-5607764
Gene expression (Transcription) R-HSA-74160
Hedgehog 'off' state R-HSA-5610787
KEAP1-NFE2L2 pathway R-HSA-9755511
Generic Transcription Pathway R-HSA-212436
G1/S Transition R-HSA-69206
Nervous system development R-HSA-9675108
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX2 R-HSA-8878166
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cytokine Signaling in Immune system R-HSA-1280215
Deubiquitination R-HSA-5688426
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCERI mediated NF-kB activation R-HSA-2871837
TCR signaling R-HSA-202403
DNA Replication Pre-Initiation R-HSA-69002
Disorders of transmembrane transporters R-HSA-5619115
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of RNA R-HSA-8953854
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of proteins R-HSA-392499
C-type lectin receptors (CLRs) R-HSA-5621481
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle, Mitotic R-HSA-69278
Cellular response to hypoxia R-HSA-1234174
Signaling by Hedgehog R-HSA-5358351
Assembly of the pre-replicative complex R-HSA-68867
ABC-family proteins mediated transport R-HSA-382556
Innate Immune System R-HSA-168249
MAPK family signaling cascades R-HSA-5683057
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RAF/MAP kinase cascade R-HSA-5673001
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of polyamines R-HSA-351202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic G1 phase and G1/S transition R-HSA-453279
Neddylation R-HSA-8951664
PIP3 activates AKT signaling R-HSA-1257604
G1/S DNA Damage Checkpoints R-HSA-69615
UCH proteinases R-HSA-5689603
Switching of origins to a post-replicative state R-HSA-69052
MAPK6/MAPK4 signaling R-HSA-5687128
Transcriptional regulation by RUNX1 R-HSA-8878171
M Phase R-HSA-68886
Signaling by the B Cell Receptor (BCR) R-HSA-983705
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism R-HSA-1430728
Developmental Biology R-HSA-1266738
Regulation of RUNX2 expression and activity R-HSA-8939902
HIV Infection R-HSA-162906
Axon guidance R-HSA-422475
Mitotic G2-G2/M phases R-HSA-453274
Intracellular signaling by second messengers R-HSA-9006925
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Nuclear events mediated by NFE2L2 R-HSA-9759194
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transport of small molecules R-HSA-382551
DNA Replication R-HSA-69306
ABC transporter disorders R-HSA-5619084
Class I MHC mediated antigen processing & presentation R-HSA-983169
Synthesis of DNA R-HSA-69239
Regulation of RAS by GAPs R-HSA-5658442
G2/M Checkpoints R-HSA-69481
Cellular responses to stress R-HSA-2262752
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by NOTCH4 R-HSA-9013694

Expression Atlas ENSG00000100902
NCBI gene (formerly Entrezgene) 5687
GeneCards 9535
HGNC Symbol HGNC:9535
MIM gene 602855
MIM morbid 608446
UniProtKB Gene Name P60900
WikiGene 5687
Gene: PSMC2
Ensembl ID : ENSG00000161057
Description: proteasome 26S subunit, ATPase 2
Gene Synonyms: MSS1,NBLA10058,RPT1,S7
5 APIs:
222 Possible Orthologues:

Cell Cycle R-HSA-1640170
Metabolism of RNA R-HSA-8953854
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
Activation of NF-kappaB in B cells R-HSA-1169091
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
Gene expression (Transcription) R-HSA-74160
Vif-mediated degradation of APOBEC3G R-HSA-180585
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G2/M Transition R-HSA-69275
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Cellular response to chemical stress R-HSA-9711123
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Metaphase and Anaphase R-HSA-2555396
Neddylation R-HSA-8951664
Neutrophil degranulation R-HSA-6798695
Regulation of PTEN stability and activity R-HSA-8948751
Intracellular signaling by second messengers R-HSA-9006925
Downstream TCR signaling R-HSA-202424
M Phase R-HSA-68886
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Separation of Sister Chromatids R-HSA-2467813
Ub-specific processing proteases R-HSA-5689880
G1/S Transition R-HSA-69206
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'on' state R-HSA-5632684
Signal Transduction R-HSA-162582
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants are degraded by ERAD R-HSA-5362768
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Dependent G1 DNA Damage Response R-HSA-69563
FCERI mediated NF-kB activation R-HSA-2871837
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK1/MAPK3 signaling R-HSA-5684996
Vpu mediated degradation of CD4 R-HSA-180534
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
DNA Replication R-HSA-69306
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
C-type lectin receptors (CLRs) R-HSA-5621481
RNA Polymerase II Transcription R-HSA-73857
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of proteins R-HSA-392499
p53-Independent DNA Damage Response R-HSA-69610
Mitotic Anaphase R-HSA-68882
Antigen processing-Cross presentation R-HSA-1236975
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
TCR signaling R-HSA-202403
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PIP3 activates AKT signaling R-HSA-1257604
Cyclin E associated events during G1/S transition R-HSA-69202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cellular responses to stress R-HSA-2262752
Orc1 removal from chromatin R-HSA-68949
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle Checkpoints R-HSA-69620
Transport of small molecules R-HSA-382551
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
Cytokine Signaling in Immune system R-HSA-1280215
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Axon guidance R-HSA-422475
Deubiquitination R-HSA-5688426
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Metabolism R-HSA-1430728
Degradation of AXIN R-HSA-4641257
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle, Mitotic R-HSA-69278
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ER-Phagosome pathway R-HSA-1236974
Assembly of the pre-replicative complex R-HSA-68867
HIV Infection R-HSA-162906
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX3 R-HSA-8878159
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of RAS by GAPs R-HSA-5658442
MAPK family signaling cascades R-HSA-5683057
Class I MHC mediated antigen processing & presentation R-HSA-983169
Beta-catenin independent WNT signaling R-HSA-3858494
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle R-HSA-1640170
Metabolism of polyamines R-HSA-351202
ABC transporter disorders R-HSA-5619084
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Hedgehog ligand biogenesis R-HSA-5358346
Hh mutants abrogate ligand secretion R-HSA-5387390
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH4 R-HSA-9013694
Degradation of DVL R-HSA-4641258
Interleukin-1 family signaling R-HSA-446652
Signaling by WNT R-HSA-195721
Negative regulation of NOTCH4 signaling R-HSA-9604323
Stabilization of p53 R-HSA-69541
PTEN Regulation R-HSA-6807070
Signaling by ROBO receptors R-HSA-376176
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Developmental Biology R-HSA-1266738
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
Asymmetric localization of PCP proteins R-HSA-4608870
Immune System R-HSA-168256
Metabolism of amino acids and derivatives R-HSA-71291
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
RAF/MAP kinase cascade R-HSA-5673001
Regulation of Apoptosis R-HSA-169911
Switching of origins to a post-replicative state R-HSA-69052
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Nervous system development R-HSA-9675108
Synthesis of DNA R-HSA-69239
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M Checkpoints R-HSA-69481
Programmed Cell Death R-HSA-5357801
Adaptive Immune System R-HSA-1280218
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Nuclear events mediated by NFE2L2 R-HSA-9759194
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PCP/CE pathway R-HSA-4086400
Cellular response to hypoxia R-HSA-1234174
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
G2/M Transition R-HSA-69275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX3 R-HSA-8878159
PCP/CE pathway R-HSA-4086400
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX1 R-HSA-8878171
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK1/MAPK3 signaling R-HSA-5684996
NIK-->noncanonical NF-kB signaling R-HSA-5676590
PIP3 activates AKT signaling R-HSA-1257604
Neutrophil degranulation R-HSA-6798695
Assembly of the pre-replicative complex R-HSA-68867
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RAS by GAPs R-HSA-5658442
Signaling by WNT R-HSA-195721
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vpu mediated degradation of CD4 R-HSA-180534
Post-translational protein modification R-HSA-597592
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Hh mutants abrogate ligand secretion R-HSA-5387390
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
Programmed Cell Death R-HSA-5357801
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Interleukins R-HSA-449147
Ub-specific processing proteases R-HSA-5689880
CLEC7A (Dectin-1) signaling R-HSA-5607764
Nervous system development R-HSA-9675108
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Independent DNA Damage Response R-HSA-69610
Mitotic Metaphase and Anaphase R-HSA-2555396
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Infectious disease R-HSA-5663205
Metabolism of polyamines R-HSA-351202
Host Interactions of HIV factors R-HSA-162909
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'on' state R-HSA-5632684
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by NOTCH4 R-HSA-9013694
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
PTEN Regulation R-HSA-6807070
Regulation of mitotic cell cycle R-HSA-453276
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
FCERI mediated NF-kB activation R-HSA-2871837
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Dependent G1 DNA Damage Response R-HSA-69563
Orc1 removal from chromatin R-HSA-68949
Gene expression (Transcription) R-HSA-74160
ER-Phagosome pathway R-HSA-1236974
HIV Infection R-HSA-162906
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Synthesis of DNA R-HSA-69239
Mitotic G2-G2/M phases R-HSA-453274
Signal Transduction R-HSA-162582
Hh mutants are degraded by ERAD R-HSA-5362768
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Cellular response to hypoxia R-HSA-1234174
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
Regulation of Apoptosis R-HSA-169911
ABC transporter disorders R-HSA-5619084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Hedgehog R-HSA-5358351
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
Developmental Biology R-HSA-1266738
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Stabilization of p53 R-HSA-69541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI1 by the proteasome R-HSA-5610780
DNA Replication R-HSA-69306
Regulation of RUNX2 expression and activity R-HSA-8939902
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
Transport of small molecules R-HSA-382551
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of amino acids and derivatives R-HSA-71291
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX2 R-HSA-8878166
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of RNA R-HSA-8953854
RNA Polymerase II Transcription R-HSA-73857
Hedgehog ligand biogenesis R-HSA-5358346
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
Regulation of PTEN stability and activity R-HSA-8948751
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'off' state R-HSA-5610787
Innate Immune System R-HSA-168249
Asymmetric localization of PCP proteins R-HSA-4608870
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic Anaphase R-HSA-68882
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
G2/M Checkpoints R-HSA-69481
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Regulation of mitotic cell cycle R-HSA-453276
Neddylation R-HSA-8951664
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Synthesis of DNA R-HSA-69239
Post-translational protein modification R-HSA-597592
Cell Cycle, Mitotic R-HSA-69278
p53-Independent DNA Damage Response R-HSA-69610
Cyclin E associated events during G1/S transition R-HSA-69202
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 signaling R-HSA-9020702
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vif-mediated degradation of APOBEC3G R-HSA-180585
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by NOTCH4 R-HSA-9013694
Degradation of DVL R-HSA-4641258
Switching of origins to a post-replicative state R-HSA-69052
Cellular responses to stress R-HSA-2262752
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
UCH proteinases R-HSA-5689603
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX2 expression and activity R-HSA-8939902
PIP3 activates AKT signaling R-HSA-1257604
Hh mutants are degraded by ERAD R-HSA-5362768
Beta-catenin independent WNT signaling R-HSA-3858494
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1/S Transition R-HSA-69206
Transcriptional regulation by RUNX2 R-HSA-8878166
DNA Replication Pre-Initiation R-HSA-69002
PCP/CE pathway R-HSA-4086400
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic G1 phase and G1/S transition R-HSA-453279
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
S Phase R-HSA-69242
Developmental Biology R-HSA-1266738
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of polyamines R-HSA-351202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream TCR signaling R-HSA-202424
Hedgehog ligand biogenesis R-HSA-5358346
DNA Replication R-HSA-69306
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RAS by GAPs R-HSA-5658442
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Separation of Sister Chromatids R-HSA-2467813
G2/M Checkpoints R-HSA-69481
Degradation of AXIN R-HSA-4641257
Interleukin-1 family signaling R-HSA-446652
Ub-specific processing proteases R-HSA-5689880
Regulation of PTEN stability and activity R-HSA-8948751
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by NOTCH R-HSA-157118
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activation of NF-kappaB in B cells R-HSA-1169091
ABC transporter disorders R-HSA-5619084
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
Transport of small molecules R-HSA-382551
MAPK6/MAPK4 signaling R-HSA-5687128
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'off' state R-HSA-5610787
PTEN Regulation R-HSA-6807070
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX3 R-HSA-8878159
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of NOTCH4 signaling R-HSA-9604323
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by Hedgehog R-HSA-5358351
G1/S DNA Damage Checkpoints R-HSA-69615
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
MAPK family signaling cascades R-HSA-5683057
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1 DNA Damage Response R-HSA-69563
RAF/MAP kinase cascade R-HSA-5673001
Host Interactions of HIV factors R-HSA-162909
Vpu mediated degradation of CD4 R-HSA-180534
Programmed Cell Death R-HSA-5357801
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
M Phase R-HSA-68886
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
FCERI mediated NF-kB activation R-HSA-2871837
Stabilization of p53 R-HSA-69541
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
TCR signaling R-HSA-202403
Metabolism R-HSA-1430728
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
Regulation of Apoptosis R-HSA-169911
Disease R-HSA-1643685
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing-Cross presentation R-HSA-1236975
Disorders of transmembrane transporters R-HSA-5619115
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Gene expression (Transcription) R-HSA-74160
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Anaphase R-HSA-68882
Deubiquitination R-HSA-5688426
Signaling by Interleukins R-HSA-449147
Metabolism of amino acids and derivatives R-HSA-71291
ABC-family proteins mediated transport R-HSA-382556
Orc1 removal from chromatin R-HSA-68949
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of proteins R-HSA-392499
Assembly of the pre-replicative complex R-HSA-68867
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'off' state R-HSA-5610787
Cellular response to hypoxia R-HSA-1234174
DNA Replication R-HSA-69306
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RAS by GAPs R-HSA-5658442
Axon guidance R-HSA-422475
ABC transporter disorders R-HSA-5619084
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 signaling R-HSA-9020702
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism R-HSA-1430728
Metabolism of polyamines R-HSA-351202
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog ligand biogenesis R-HSA-5358346
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 family signaling R-HSA-446652
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
MAPK family signaling cascades R-HSA-5683057
Apoptosis R-HSA-109581
Hh mutants abrogate ligand secretion R-HSA-5387390
Infectious disease R-HSA-5663205
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX2 R-HSA-8878166
Orc1 removal from chromatin R-HSA-68949
Vpu mediated degradation of CD4 R-HSA-180534
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI2 by the proteasome R-HSA-5610783
UCH proteinases R-HSA-5689603
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PTEN Regulation R-HSA-6807070
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Beta-catenin independent WNT signaling R-HSA-3858494
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Class I MHC mediated antigen processing & presentation R-HSA-983169
G2/M Transition R-HSA-69275
M Phase R-HSA-68886
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog 'on' state R-HSA-5632684
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of RNA R-HSA-8953854
Degradation of beta-catenin by the destruction complex R-HSA-195253
Activation of NF-kappaB in B cells R-HSA-1169091
G1/S Transition R-HSA-69206
Post-translational protein modification R-HSA-597592
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Assembly of the pre-replicative complex R-HSA-68867
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Downstream TCR signaling R-HSA-202424
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cell Cycle Checkpoints R-HSA-69620
Degradation of AXIN R-HSA-4641257
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Programmed Cell Death R-HSA-5357801
p53-Independent DNA Damage Response R-HSA-69610
Signaling by WNT R-HSA-195721
Synthesis of DNA R-HSA-69239
ABC-family proteins mediated transport R-HSA-382556
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
HIV Infection R-HSA-162906
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Dependent G1 DNA Damage Response R-HSA-69563
ER-Phagosome pathway R-HSA-1236974
Transport of small molecules R-HSA-382551
MAPK1/MAPK3 signaling R-HSA-5684996
TCF dependent signaling in response to WNT R-HSA-201681
Generic Transcription Pathway R-HSA-212436
Degradation of DVL R-HSA-4641258
Signaling by Hedgehog R-HSA-5358351
Vif-mediated degradation of APOBEC3G R-HSA-180585
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle, Mitotic R-HSA-69278
Host Interactions of HIV factors R-HSA-162909
PCP/CE pathway R-HSA-4086400
DNA Replication Pre-Initiation R-HSA-69002
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Deubiquitination R-HSA-5688426
Defective CFTR causes cystic fibrosis R-HSA-5678895
PIP3 activates AKT signaling R-HSA-1257604
Mitotic Metaphase and Anaphase R-HSA-2555396
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Neutrophil degranulation R-HSA-6798695
Signaling by the B Cell Receptor (BCR) R-HSA-983705
C-type lectin receptors (CLRs) R-HSA-5621481
Antigen processing-Cross presentation R-HSA-1236975
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle R-HSA-1640170
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
FCERI mediated NF-kB activation R-HSA-2871837
G2/M Checkpoints R-HSA-69481
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Degradation of GLI1 by the proteasome R-HSA-5610780
Immune System R-HSA-168256
Regulation of PTEN stability and activity R-HSA-8948751
Disorders of transmembrane transporters R-HSA-5619115
Cyclin E associated events during G1/S transition R-HSA-69202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic Anaphase R-HSA-68882
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by NOTCH4 R-HSA-9013694
Gene expression (Transcription) R-HSA-74160
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Generic Transcription Pathway R-HSA-212436
ABC-family proteins mediated transport R-HSA-382556
Separation of Sister Chromatids R-HSA-2467813
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
DNA Replication Pre-Initiation R-HSA-69002
Mitotic Metaphase and Anaphase R-HSA-2555396
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ub-specific processing proteases R-HSA-5689880
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disease R-HSA-1643685
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Switching of origins to a post-replicative state R-HSA-69052
MAPK family signaling cascades R-HSA-5683057
Degradation of AXIN R-HSA-4641257
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of proteins R-HSA-392499
Neutrophil degranulation R-HSA-6798695
ABC transporter disorders R-HSA-5619084
Orc1 removal from chromatin R-HSA-68949
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
UCH proteinases R-HSA-5689603
DNA Replication R-HSA-69306
Gene expression (Transcription) R-HSA-74160
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stimuli R-HSA-8953897
Asymmetric localization of PCP proteins R-HSA-4608870
Immune System R-HSA-168256
Cell Cycle, Mitotic R-HSA-69278
TCR signaling R-HSA-202403
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PCP/CE pathway R-HSA-4086400
Metabolism of polyamines R-HSA-351202
Mitotic Anaphase R-HSA-68882
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signal Transduction R-HSA-162582
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Infectious disease R-HSA-5663205
HIV Infection R-HSA-162906
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Downstream TCR signaling R-HSA-202424
Vpu mediated degradation of CD4 R-HSA-180534
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Apoptosis R-HSA-109581
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
KEAP1-NFE2L2 pathway R-HSA-9755511
G2/M Transition R-HSA-69275
Class I MHC mediated antigen processing & presentation R-HSA-983169
RNA Polymerase II Transcription R-HSA-73857
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
PTEN Regulation R-HSA-6807070
Beta-catenin independent WNT signaling R-HSA-3858494
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of Apoptosis R-HSA-169911
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Independent DNA Damage Response R-HSA-69610
Regulation of PTEN stability and activity R-HSA-8948751
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH4 R-HSA-9013694
Nervous system development R-HSA-9675108
Cell Cycle R-HSA-1640170
Cellular response to hypoxia R-HSA-1234174
Cytokine Signaling in Immune system R-HSA-1280215
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RAS by GAPs R-HSA-5658442
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX2 expression and activity R-HSA-8939902
FCERI mediated NF-kB activation R-HSA-2871837
Axon guidance R-HSA-422475
Hh mutants are degraded by ERAD R-HSA-5362768
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PIP3 activates AKT signaling R-HSA-1257604
Disorders of transmembrane transporters R-HSA-5619115
Transcriptional regulation by RUNX1 R-HSA-8878171
Adaptive Immune System R-HSA-1280218
M Phase R-HSA-68886
Cyclin E associated events during G1/S transition R-HSA-69202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to chemical stress R-HSA-9711123
Programmed Cell Death R-HSA-5357801
Signaling by WNT R-HSA-195721
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transport of small molecules R-HSA-382551
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
Post-translational protein modification R-HSA-597592
S Phase R-HSA-69242
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Interleukin-1 family signaling R-HSA-446652
Signaling by Interleukins R-HSA-449147
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
Deubiquitination R-HSA-5688426
Mitotic G2-G2/M phases R-HSA-453274
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Disorders of transmembrane transporters R-HSA-5619115
Transport of small molecules R-HSA-382551
Degradation of AXIN R-HSA-4641257
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism R-HSA-1430728
Orc1 removal from chromatin R-HSA-68949
Cell Cycle Checkpoints R-HSA-69620
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Intracellular signaling by second messengers R-HSA-9006925
S Phase R-HSA-69242
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of polyamines R-HSA-351202
Programmed Cell Death R-HSA-5357801
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
HIV Infection R-HSA-162906
Degradation of beta-catenin by the destruction complex R-HSA-195253
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX3 expression and activity R-HSA-8941858
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by NOTCH R-HSA-157118
RAF/MAP kinase cascade R-HSA-5673001
Nuclear events mediated by NFE2L2 R-HSA-9759194
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TCR signaling R-HSA-202403
Interleukin-1 family signaling R-HSA-446652
PTEN Regulation R-HSA-6807070
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants are degraded by ERAD R-HSA-5362768
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Infectious disease R-HSA-5663205
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Interleukin-1 signaling R-HSA-9020702
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Generic Transcription Pathway R-HSA-212436
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX2 R-HSA-8878166
Deubiquitination R-HSA-5688426
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular responses to stress R-HSA-2262752
Regulation of RAS by GAPs R-HSA-5658442
Developmental Biology R-HSA-1266738
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
M Phase R-HSA-68886
RNA Polymerase II Transcription R-HSA-73857
Regulation of mitotic cell cycle R-HSA-453276
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Hedgehog R-HSA-5358351
Antigen processing-Cross presentation R-HSA-1236975
ABC transporter disorders R-HSA-5619084
Ub-specific processing proteases R-HSA-5689880
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Apoptosis R-HSA-109581
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Innate Immune System R-HSA-168249
Separation of Sister Chromatids R-HSA-2467813
Regulation of RUNX2 expression and activity R-HSA-8939902
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
DNA Replication Pre-Initiation R-HSA-69002
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of GLI1 by the proteasome R-HSA-5610780
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
ABC-family proteins mediated transport R-HSA-382556
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to hypoxia R-HSA-1234174
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of proteins R-HSA-392499
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Negative regulation of NOTCH4 signaling R-HSA-9604323
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Immune System R-HSA-168256
Mitotic G1 phase and G1/S transition R-HSA-453279
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog 'off' state R-HSA-5610787
G1/S DNA Damage Checkpoints R-HSA-69615
TCF dependent signaling in response to WNT R-HSA-201681
ER-Phagosome pathway R-HSA-1236974
UCH proteinases R-HSA-5689603
Mitotic Metaphase and Anaphase R-HSA-2555396
G1/S Transition R-HSA-69206
Neutrophil degranulation R-HSA-6798695
Stabilization of p53 R-HSA-69541
Degradation of DVL R-HSA-4641258
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Class I MHC mediated antigen processing & presentation R-HSA-983169
Gene expression (Transcription) R-HSA-74160
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Activation of NF-kappaB in B cells R-HSA-1169091
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Transition R-HSA-69275
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle R-HSA-1640170
Hedgehog 'on' state R-HSA-5632684
Neddylation R-HSA-8951664
Adaptive Immune System R-HSA-1280218
KEAP1-NFE2L2 pathway R-HSA-9755511
PIP3 activates AKT signaling R-HSA-1257604
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of GLI2 by the proteasome R-HSA-5610783
Assembly of the pre-replicative complex R-HSA-68867
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
Signaling by NOTCH4 R-HSA-9013694
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G1/S Transition R-HSA-69206
Metabolism of proteins R-HSA-392499
Cell Cycle R-HSA-1640170
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ER-Phagosome pathway R-HSA-1236974
Stabilization of p53 R-HSA-69541
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stress R-HSA-2262752
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Infectious disease R-HSA-5663205
Signaling by Hedgehog R-HSA-5358351
Adaptive Immune System R-HSA-1280218
Programmed Cell Death R-HSA-5357801
UCH proteinases R-HSA-5689603
Disease R-HSA-1643685
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH4 R-HSA-9013694
Cellular response to hypoxia R-HSA-1234174
ABC-family proteins mediated transport R-HSA-382556
KEAP1-NFE2L2 pathway R-HSA-9755511
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
G2/M Transition R-HSA-69275
Neddylation R-HSA-8951664
PCP/CE pathway R-HSA-4086400
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Deubiquitination R-HSA-5688426
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK family signaling cascades R-HSA-5683057
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Regulation of mitotic cell cycle R-HSA-453276
Vpu mediated degradation of CD4 R-HSA-180534
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Axon guidance R-HSA-422475
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle, Mitotic R-HSA-69278
Neutrophil degranulation R-HSA-6798695
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Downstream TCR signaling R-HSA-202424
Mitotic Anaphase R-HSA-68882
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants abrogate ligand secretion R-HSA-5387390
Transcriptional regulation by RUNX2 R-HSA-8878166
CLEC7A (Dectin-1) signaling R-HSA-5607764
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
TCR signaling R-HSA-202403
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of PTEN stability and activity R-HSA-8948751
Asymmetric localization of PCP proteins R-HSA-4608870
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
HIV Infection R-HSA-162906
Nuclear events mediated by NFE2L2 R-HSA-9759194
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Innate Immune System R-HSA-168249
Synthesis of DNA R-HSA-69239
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Mitotic G2-G2/M phases R-HSA-453274
Generic Transcription Pathway R-HSA-212436
Separation of Sister Chromatids R-HSA-2467813
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
C-type lectin receptors (CLRs) R-HSA-5621481
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transport of small molecules R-HSA-382551
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog 'on' state R-HSA-5632684
Disorders of transmembrane transporters R-HSA-5619115
Degradation of DVL R-HSA-4641258
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Orc1 removal from chromatin R-HSA-68949
Post-translational protein modification R-HSA-597592
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
Ub-specific processing proteases R-HSA-5689880
Degradation of AXIN R-HSA-4641257
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of Apoptosis R-HSA-169911
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Assembly of the pre-replicative complex R-HSA-68867
MAPK6/MAPK4 signaling R-HSA-5687128
Host Interactions of HIV factors R-HSA-162909
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of RNA R-HSA-8953854
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH R-HSA-157118
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX2 expression and activity R-HSA-8939902
Signal Transduction R-HSA-162582
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Interleukins R-HSA-449147
Interleukin-1 family signaling R-HSA-446652
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Apoptosis R-HSA-109581
Signaling by ROBO receptors R-HSA-376176
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
DNA Replication R-HSA-69306
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
G1/S DNA Damage Checkpoints R-HSA-69615
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 family signaling R-HSA-446652
Mitotic Anaphase R-HSA-68882
TCR signaling R-HSA-202403
Signaling by NOTCH4 R-HSA-9013694
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants are degraded by ERAD R-HSA-5362768
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
Intracellular signaling by second messengers R-HSA-9006925
Cellular responses to stimuli R-HSA-8953897
Asymmetric localization of PCP proteins R-HSA-4608870
Adaptive Immune System R-HSA-1280218
Transport of small molecules R-HSA-382551
Synthesis of DNA R-HSA-69239
Metabolism of amino acids and derivatives R-HSA-71291
M Phase R-HSA-68886
Deubiquitination R-HSA-5688426
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent DNA Damage Response R-HSA-69610
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog 'off' state R-HSA-5610787
ABC-family proteins mediated transport R-HSA-382556
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of PTEN stability and activity R-HSA-8948751
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Signaling by Hedgehog R-HSA-5358351
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of RNA R-HSA-8953854
Degradation of AXIN R-HSA-4641257
KEAP1-NFE2L2 pathway R-HSA-9755511
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Transcriptional regulation by RUNX2 R-HSA-8878166
Vpu mediated degradation of CD4 R-HSA-180534
Disorders of transmembrane transporters R-HSA-5619115
Gene expression (Transcription) R-HSA-74160
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of Apoptosis R-HSA-169911
Generic Transcription Pathway R-HSA-212436
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI2 by the proteasome R-HSA-5610783
DNA Replication R-HSA-69306
Switching of origins to a post-replicative state R-HSA-69052
Ub-specific processing proteases R-HSA-5689880
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Host Interactions of HIV factors R-HSA-162909
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
S Phase R-HSA-69242
G2/M Checkpoints R-HSA-69481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic Metaphase and Anaphase R-HSA-2555396
Assembly of the pre-replicative complex R-HSA-68867
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX1 R-HSA-8878171
NIK-->noncanonical NF-kB signaling R-HSA-5676590
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cell Cycle, Mitotic R-HSA-69278
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of RAS by GAPs R-HSA-5658442
Cellular response to chemical stress R-HSA-9711123
UCH proteinases R-HSA-5689603
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Interleukin-1 signaling R-HSA-9020702
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by WNT R-HSA-195721
Defective CFTR causes cystic fibrosis R-HSA-5678895
G2/M Transition R-HSA-69275
Degradation of DVL R-HSA-4641258
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G2-G2/M phases R-HSA-453274
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle Checkpoints R-HSA-69620
Neutrophil degranulation R-HSA-6798695
Metabolism of proteins R-HSA-392499
Signaling by ROBO receptors R-HSA-376176
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Axon guidance R-HSA-422475
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH R-HSA-157118
G1/S DNA Damage Checkpoints R-HSA-69615
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism R-HSA-1430728
Nervous system development R-HSA-9675108
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle R-HSA-1640170
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
Signaling by Interleukins R-HSA-449147
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream TCR signaling R-HSA-202424
HIV Infection R-HSA-162906
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
RAF/MAP kinase cascade R-HSA-5673001
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog 'on' state R-HSA-5632684
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Stabilization of p53 R-HSA-69541
Metabolism of polyamines R-HSA-351202
Signal Transduction R-HSA-162582
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
PCP/CE pathway R-HSA-4086400
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S Transition R-HSA-69206
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
DNA Replication Pre-Initiation R-HSA-69002
Developmental Biology R-HSA-1266738
Apoptosis R-HSA-109581
Negative regulation of NOTCH4 signaling R-HSA-9604323
Immune System R-HSA-168256
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
Infectious disease R-HSA-5663205
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of NF-kappaB in B cells R-HSA-1169091
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signal Transduction R-HSA-162582
Cellular response to chemical stress R-HSA-9711123
G1/S DNA Damage Checkpoints R-HSA-69615
Antigen processing-Cross presentation R-HSA-1236975
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of polyamines R-HSA-351202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
DNA Replication R-HSA-69306
Transcriptional regulation by RUNX3 R-HSA-8878159
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Synthesis of DNA R-HSA-69239
Cellular responses to stress R-HSA-2262752
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Adaptive Immune System R-HSA-1280218
G2/M Checkpoints R-HSA-69481
Neddylation R-HSA-8951664
Hh mutants are degraded by ERAD R-HSA-5362768
UCH proteinases R-HSA-5689603
Ub-specific processing proteases R-HSA-5689880
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Vpu mediated degradation of CD4 R-HSA-180534
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI1 by the proteasome R-HSA-5610780
Cell Cycle, Mitotic R-HSA-69278
Degradation of DVL R-HSA-4641258
Signaling by WNT R-HSA-195721
Signaling by ROBO receptors R-HSA-376176
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
M Phase R-HSA-68886
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G2/M Transition R-HSA-69275
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of amino acids and derivatives R-HSA-71291
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 family signaling R-HSA-446652
KEAP1-NFE2L2 pathway R-HSA-9755511
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants abrogate ligand secretion R-HSA-5387390
Separation of Sister Chromatids R-HSA-2467813
Activation of NF-kappaB in B cells R-HSA-1169091
Programmed Cell Death R-HSA-5357801
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Hedgehog ligand biogenesis R-HSA-5358346
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 signaling R-HSA-9020702
Cell Cycle R-HSA-1640170
HIV Infection R-HSA-162906
Mitotic G2-G2/M phases R-HSA-453274
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
FCERI mediated NF-kB activation R-HSA-2871837
Developmental Biology R-HSA-1266738
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hedgehog 'on' state R-HSA-5632684
Metabolism of proteins R-HSA-392499
TCF dependent signaling in response to WNT R-HSA-201681
TCR signaling R-HSA-202403
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Anaphase R-HSA-68882
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Orc1 removal from chromatin R-HSA-68949
Axon guidance R-HSA-422475
Regulation of mitotic cell cycle R-HSA-453276
Switching of origins to a post-replicative state R-HSA-69052
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stimuli R-HSA-8953897
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of RNA R-HSA-8953854
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Independent DNA Damage Response R-HSA-69610
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
PIP3 activates AKT signaling R-HSA-1257604
Neutrophil degranulation R-HSA-6798695
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Host Interactions of HIV factors R-HSA-162909
Defective CFTR causes cystic fibrosis R-HSA-5678895
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
DNA Replication Pre-Initiation R-HSA-69002
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G1/S Transition R-HSA-69206
Regulation of RUNX2 expression and activity R-HSA-8939902
ABC transporter disorders R-HSA-5619084
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
C-type lectin receptors (CLRs) R-HSA-5621481
Transport of small molecules R-HSA-382551
MAPK family signaling cascades R-HSA-5683057
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to hypoxia R-HSA-1234174
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of Apoptosis R-HSA-169911
Disease R-HSA-1643685
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by NOTCH4 R-HSA-9013694
Signaling by Hedgehog R-HSA-5358351
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of RUNX3 expression and activity R-HSA-8941858
Beta-catenin independent WNT signaling R-HSA-3858494
Post-translational protein modification R-HSA-597592
Cell Cycle Checkpoints R-HSA-69620
Assembly of the pre-replicative complex R-HSA-68867
Hedgehog 'off' state R-HSA-5610787
Metabolism R-HSA-1430728
Infectious disease R-HSA-5663205
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
Regulation of RAS by GAPs R-HSA-5658442
Programmed Cell Death R-HSA-5357801
Neutrophil degranulation R-HSA-6798695
Cell Cycle, Mitotic R-HSA-69278
Metabolism of RNA R-HSA-8953854
Signaling by WNT R-HSA-195721
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Orc1 removal from chromatin R-HSA-68949
Assembly of the pre-replicative complex R-HSA-68867
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
M Phase R-HSA-68886
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of mitotic cell cycle R-HSA-453276
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ROBO receptors R-HSA-376176
Host Interactions of HIV factors R-HSA-162909
Ub-specific processing proteases R-HSA-5689880
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC transporter disorders R-HSA-5619084
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of beta-catenin by the destruction complex R-HSA-195253
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Apoptosis R-HSA-109581
Hedgehog 'on' state R-HSA-5632684
TCF dependent signaling in response to WNT R-HSA-201681
Synthesis of DNA R-HSA-69239
UCH proteinases R-HSA-5689603
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH R-HSA-157118
FCERI mediated NF-kB activation R-HSA-2871837
PTEN Regulation R-HSA-6807070
Disorders of transmembrane transporters R-HSA-5619115
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of AXIN R-HSA-4641257
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Class I MHC mediated antigen processing & presentation R-HSA-983169
C-type lectin receptors (CLRs) R-HSA-5621481
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream TCR signaling R-HSA-202424
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Checkpoints R-HSA-69481
Hh mutants are degraded by ERAD R-HSA-5362768
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to chemical stress R-HSA-9711123
Cell Cycle Checkpoints R-HSA-69620
Antigen processing-Cross presentation R-HSA-1236975
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
PIP3 activates AKT signaling R-HSA-1257604
ER-Phagosome pathway R-HSA-1236974
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Separation of Sister Chromatids R-HSA-2467813
DNA Replication R-HSA-69306
Nervous system development R-HSA-9675108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Mitotic G2-G2/M phases R-HSA-453274
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin E associated events during G1/S transition R-HSA-69202
Negative regulation of NOTCH4 signaling R-HSA-9604323
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic Anaphase R-HSA-68882
ABC-family proteins mediated transport R-HSA-382556
Regulation of Apoptosis R-HSA-169911
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle R-HSA-1640170
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
CLEC7A (Dectin-1) signaling R-HSA-5607764
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of DVL R-HSA-4641258
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by NOTCH4 R-HSA-9013694
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PCP/CE pathway R-HSA-4086400
Axon guidance R-HSA-422475
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Stabilization of p53 R-HSA-69541
Neddylation R-HSA-8951664
Regulation of RUNX3 expression and activity R-HSA-8941858
Defective CFTR causes cystic fibrosis R-HSA-5678895
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Interleukin-1 family signaling R-HSA-446652
Developmental Biology R-HSA-1266738
Signaling by Hedgehog R-HSA-5358351
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of polyamines R-HSA-351202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transport of small molecules R-HSA-382551
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S Transition R-HSA-69206
Degradation of GLI2 by the proteasome R-HSA-5610783
G2/M Transition R-HSA-69275
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
DNA Replication Pre-Initiation R-HSA-69002
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Programmed Cell Death R-HSA-5357801
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of Apoptosis R-HSA-169911
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX3 R-HSA-8878159
Interleukin-1 family signaling R-HSA-446652
MAPK family signaling cascades R-HSA-5683057
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Assembly of the pre-replicative complex R-HSA-68867
Mitotic G1 phase and G1/S transition R-HSA-453279
Post-translational protein modification R-HSA-597592
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
UCH proteinases R-HSA-5689603
Signal Transduction R-HSA-162582
FCERI mediated NF-kB activation R-HSA-2871837
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
Antigen processing-Cross presentation R-HSA-1236975
ABC transporter disorders R-HSA-5619084
Metabolism of amino acids and derivatives R-HSA-71291
Deubiquitination R-HSA-5688426
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Separation of Sister Chromatids R-HSA-2467813
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Stabilization of p53 R-HSA-69541
Signaling by NOTCH4 R-HSA-9013694
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle Checkpoints R-HSA-69620
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
Regulation of RAS by GAPs R-HSA-5658442
Host Interactions of HIV factors R-HSA-162909
Switching of origins to a post-replicative state R-HSA-69052
PIP3 activates AKT signaling R-HSA-1257604
M Phase R-HSA-68886
Nuclear events mediated by NFE2L2 R-HSA-9759194
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
Degradation of AXIN R-HSA-4641257
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK1/MAPK3 signaling R-HSA-5684996
DNA Replication Pre-Initiation R-HSA-69002
Immune System R-HSA-168256
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic G2-G2/M phases R-HSA-453274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to hypoxia R-HSA-1234174
Metabolism of RNA R-HSA-8953854
Signaling by WNT R-HSA-195721
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Activation of NF-kappaB in B cells R-HSA-1169091
Transport of small molecules R-HSA-382551
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Disorders of transmembrane transporters R-HSA-5619115
ABC-family proteins mediated transport R-HSA-382556
HIV Infection R-HSA-162906
Adaptive Immune System R-HSA-1280218
RAF/MAP kinase cascade R-HSA-5673001
Mitotic Anaphase R-HSA-68882
G2/M Transition R-HSA-69275
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
p53-Independent DNA Damage Response R-HSA-69610
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
C-type lectin receptors (CLRs) R-HSA-5621481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
TCR signaling R-HSA-202403
Neutrophil degranulation R-HSA-6798695
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PTEN Regulation R-HSA-6807070
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Infectious disease R-HSA-5663205
Neddylation R-HSA-8951664
Signaling by Hedgehog R-HSA-5358351
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mitotic cell cycle R-HSA-453276
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic Metaphase and Anaphase R-HSA-2555396
Class I MHC mediated antigen processing & presentation R-HSA-983169
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of beta-catenin by the destruction complex R-HSA-195253
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cytokine Signaling in Immune system R-HSA-1280215
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
G2/M Checkpoints R-HSA-69481
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Synthesis of DNA R-HSA-69239
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Metabolism of polyamines R-HSA-351202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'on' state R-HSA-5632684

Expression Atlas ENSG00000161057
NCBI gene (formerly Entrezgene) 5701
GeneCards 9548
HGNC Symbol HGNC:9548
MIM gene 154365
UniProtKB Gene Name P35998
WikiGene 5701
Gene: PSMA4
Ensembl ID : ENSG00000041357
Description: proteasome 20S subunit alpha 4
Gene Synonyms: HC9,HST17706
6 APIs:
250 Possible Orthologues:

Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
UCH proteinases R-HSA-5689603
Apoptosis R-HSA-109581
Separation of Sister Chromatids R-HSA-2467813
Cellular responses to stress R-HSA-2262752
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Nuclear events mediated by NFE2L2 R-HSA-9759194
ER-Phagosome pathway R-HSA-1236974
KEAP1-NFE2L2 pathway R-HSA-9755511
TCF dependent signaling in response to WNT R-HSA-201681
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of GLI1 by the proteasome R-HSA-5610780
Signal Transduction R-HSA-162582
Hedgehog 'off' state R-HSA-5610787
RNA Polymerase II Transcription R-HSA-73857
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
MAPK6/MAPK4 signaling R-HSA-5687128
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Deubiquitination R-HSA-5688426
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RAS by GAPs R-HSA-5658442
Host Interactions of HIV factors R-HSA-162909
Degradation of GLI2 by the proteasome R-HSA-5610783
Apoptosis R-HSA-109581
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by NOTCH4 R-HSA-9013694
DNA Replication R-HSA-69306
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of Apoptosis R-HSA-169911
Regulation of RUNX3 expression and activity R-HSA-8941858
Beta-catenin independent WNT signaling R-HSA-3858494
Cell Cycle Checkpoints R-HSA-69620
Regulation of PTEN stability and activity R-HSA-8948751
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
UCH proteinases R-HSA-5689603
Synthesis of DNA R-HSA-69239
Nervous system development R-HSA-9675108
Infectious disease R-HSA-5663205
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular responses to stimuli R-HSA-8953897
Cellular response to chemical stress R-HSA-9711123
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of DVL R-HSA-4641258
Mitotic G2-G2/M phases R-HSA-453274
G2/M Checkpoints R-HSA-69481
Degradation of AXIN R-HSA-4641257
Antigen processing-Cross presentation R-HSA-1236975
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to hypoxia R-HSA-1234174
Stabilization of p53 R-HSA-69541
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G2/M Transition R-HSA-69275
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Anaphase R-HSA-68882
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of RNA R-HSA-8953854
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle, Mitotic R-HSA-69278
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hedgehog ligand biogenesis R-HSA-5358346
Transport of small molecules R-HSA-382551
PCP/CE pathway R-HSA-4086400
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Dependent G1 DNA Damage Response R-HSA-69563
CLEC7A (Dectin-1) signaling R-HSA-5607764
Developmental Biology R-HSA-1266738
Defective CFTR causes cystic fibrosis R-HSA-5678895
Switching of origins to a post-replicative state R-HSA-69052
HIV Infection R-HSA-162906
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by WNT R-HSA-195721
S Phase R-HSA-69242
Intracellular signaling by second messengers R-HSA-9006925
ABC transporter disorders R-HSA-5619084
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Disorders of transmembrane transporters R-HSA-5619115
Gene expression (Transcription) R-HSA-74160
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Mitotic Metaphase and Anaphase R-HSA-2555396
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Innate Immune System R-HSA-168249
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ub-specific processing proteases R-HSA-5689880
Signaling by ROBO receptors R-HSA-376176
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PIP3 activates AKT signaling R-HSA-1257604
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 family signaling R-HSA-446652
Post-translational protein modification R-HSA-597592
ABC-family proteins mediated transport R-HSA-382556
Neddylation R-HSA-8951664
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of polyamines R-HSA-351202
Mitotic G1 phase and G1/S transition R-HSA-453279
Orc1 removal from chromatin R-HSA-68949
Assembly of the pre-replicative complex R-HSA-68867
Axon guidance R-HSA-422475
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by Interleukins R-HSA-449147
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Disease R-HSA-1643685
Hedgehog 'on' state R-HSA-5632684
Signaling by NOTCH R-HSA-157118
G1/S Transition R-HSA-69206
Interleukin-1 signaling R-HSA-9020702
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Independent DNA Damage Response R-HSA-69610
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of RUNX2 expression and activity R-HSA-8939902
TCR signaling R-HSA-202403
Metabolism R-HSA-1430728
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Immune System R-HSA-168256
Negative regulation of NOTCH4 signaling R-HSA-9604323
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
M Phase R-HSA-68886
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
RAF/MAP kinase cascade R-HSA-5673001
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vif-mediated degradation of APOBEC3G R-HSA-180585
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream TCR signaling R-HSA-202424
Programmed Cell Death R-HSA-5357801
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RUNX3 expression and activity R-HSA-8941858
Hh mutants abrogate ligand secretion R-HSA-5387390
CLEC7A (Dectin-1) signaling R-HSA-5607764
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Deubiquitination R-HSA-5688426
Transport of small molecules R-HSA-382551
Neddylation R-HSA-8951664
Activation of NF-kappaB in B cells R-HSA-1169091
Adaptive Immune System R-HSA-1280218
Generic Transcription Pathway R-HSA-212436
UCH proteinases R-HSA-5689603
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
ABC transporter disorders R-HSA-5619084
Synthesis of DNA R-HSA-69239
Metabolism of RNA R-HSA-8953854
Transcriptional regulation by RUNX3 R-HSA-8878159
Apoptosis R-HSA-109581
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hedgehog 'on' state R-HSA-5632684
ABC-family proteins mediated transport R-HSA-382556
Signaling by WNT R-HSA-195721
Developmental Biology R-HSA-1266738
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular response to chemical stress R-HSA-9711123
G1/S DNA Damage Checkpoints R-HSA-69615
S Phase R-HSA-69242
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Disease R-HSA-1643685
Interleukin-1 signaling R-HSA-9020702
Hedgehog ligand biogenesis R-HSA-5358346
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of proteins R-HSA-392499
Axon guidance R-HSA-422475
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PCP/CE pathway R-HSA-4086400
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular responses to stimuli R-HSA-8953897
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of DVL R-HSA-4641258
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G2/M Transition R-HSA-69275
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Vif-mediated degradation of APOBEC3G R-HSA-180585
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
G1/S Transition R-HSA-69206
Cell Cycle Checkpoints R-HSA-69620
Regulation of RAS by GAPs R-HSA-5658442
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic Anaphase R-HSA-68882
MAPK1/MAPK3 signaling R-HSA-5684996
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
PIP3 activates AKT signaling R-HSA-1257604
Downstream TCR signaling R-HSA-202424
Ub-specific processing proteases R-HSA-5689880
Antigen processing-Cross presentation R-HSA-1236975
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
C-type lectin receptors (CLRs) R-HSA-5621481
Interleukin-1 family signaling R-HSA-446652
ER-Phagosome pathway R-HSA-1236974
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of mitotic cell cycle R-HSA-453276
Regulation of Apoptosis R-HSA-169911
Host Interactions of HIV factors R-HSA-162909
Assembly of the pre-replicative complex R-HSA-68867
G2/M Checkpoints R-HSA-69481
Cell Cycle, Mitotic R-HSA-69278
Metabolism of polyamines R-HSA-351202
Mitotic G1 phase and G1/S transition R-HSA-453279
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Independent DNA Damage Response R-HSA-69610
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by ROBO receptors R-HSA-376176
Signaling by Hedgehog R-HSA-5358351
FCERI mediated NF-kB activation R-HSA-2871837
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle R-HSA-1640170
DNA Replication R-HSA-69306
TCR signaling R-HSA-202403
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
DNA Replication Pre-Initiation R-HSA-69002
Degradation of AXIN R-HSA-4641257
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular response to hypoxia R-HSA-1234174
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH R-HSA-157118
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Orc1 removal from chromatin R-HSA-68949
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Disorders of transmembrane transporters R-HSA-5619115
KEAP1-NFE2L2 pathway R-HSA-9755511
Separation of Sister Chromatids R-HSA-2467813
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Post-translational protein modification R-HSA-597592
Immune System R-HSA-168256
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of amino acids and derivatives R-HSA-71291
Programmed Cell Death R-HSA-5357801
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Innate Immune System R-HSA-168249
Class I MHC mediated antigen processing & presentation R-HSA-983169
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Nuclear events mediated by NFE2L2 R-HSA-9759194
Stabilization of p53 R-HSA-69541
Switching of origins to a post-replicative state R-HSA-69052
Signaling by Interleukins R-HSA-449147
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH4 R-HSA-9013694
HIV Infection R-HSA-162906
MAPK family signaling cascades R-HSA-5683057
Infectious disease R-HSA-5663205
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
RAF/MAP kinase cascade R-HSA-5673001
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX2 expression and activity R-HSA-8939902
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of PTEN stability and activity R-HSA-8948751
PTEN Regulation R-HSA-6807070
KEAP1-NFE2L2 pathway R-HSA-9755511
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of amino acids and derivatives R-HSA-71291
M Phase R-HSA-68886
Degradation of GLI2 by the proteasome R-HSA-5610783
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
Regulation of Apoptosis R-HSA-169911
Vpu mediated degradation of CD4 R-HSA-180534
FCERI mediated NF-kB activation R-HSA-2871837
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
PTEN Regulation R-HSA-6807070
Apoptosis R-HSA-109581
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to hypoxia R-HSA-1234174
Hedgehog ligand biogenesis R-HSA-5358346
Asymmetric localization of PCP proteins R-HSA-4608870
ABC-family proteins mediated transport R-HSA-382556
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by NOTCH4 R-HSA-9013694
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cytokine Signaling in Immune system R-HSA-1280215
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
UCH proteinases R-HSA-5689603
CLEC7A (Dectin-1) signaling R-HSA-5607764
Infectious disease R-HSA-5663205
Metabolism of RNA R-HSA-8953854
Cellular responses to stress R-HSA-2262752
MAPK1/MAPK3 signaling R-HSA-5684996
Nervous system development R-HSA-9675108
Vif-mediated degradation of APOBEC3G R-HSA-180585
RAF/MAP kinase cascade R-HSA-5673001
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of mitotic cell cycle R-HSA-453276
Innate Immune System R-HSA-168249
Hh mutants are degraded by ERAD R-HSA-5362768
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transcriptional regulation by RUNX2 R-HSA-8878166
RNA Polymerase II Transcription R-HSA-73857
Synthesis of DNA R-HSA-69239
S Phase R-HSA-69242
Adaptive Immune System R-HSA-1280218
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Defective CFTR causes cystic fibrosis R-HSA-5678895
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle R-HSA-1640170
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
Separation of Sister Chromatids R-HSA-2467813
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of RUNX3 expression and activity R-HSA-8941858
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RAS by GAPs R-HSA-5658442
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog 'off' state R-HSA-5610787
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Immune System R-HSA-168256
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH R-HSA-157118
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of PTEN stability and activity R-HSA-8948751
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular response to chemical stress R-HSA-9711123
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Switching of origins to a post-replicative state R-HSA-69052
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Neddylation R-HSA-8951664
G2/M Checkpoints R-HSA-69481
Assembly of the pre-replicative complex R-HSA-68867
Programmed Cell Death R-HSA-5357801
G1/S Transition R-HSA-69206
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signal Transduction R-HSA-162582
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 family signaling R-HSA-446652
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Disorders of transmembrane transporters R-HSA-5619115
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle, Mitotic R-HSA-69278
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by ROBO receptors R-HSA-376176
Class I MHC mediated antigen processing & presentation R-HSA-983169
Nuclear events mediated by NFE2L2 R-HSA-9759194
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Host Interactions of HIV factors R-HSA-162909
Cell Cycle Checkpoints R-HSA-69620
ABC transporter disorders R-HSA-5619084
Stabilization of p53 R-HSA-69541
Metabolism R-HSA-1430728
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TCR signaling R-HSA-202403
Metabolism of proteins R-HSA-392499
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G2/M Transition R-HSA-69275
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Generic Transcription Pathway R-HSA-212436
Cyclin E associated events during G1/S transition R-HSA-69202
Developmental Biology R-HSA-1266738
Degradation of GLI1 by the proteasome R-HSA-5610780
PCP/CE pathway R-HSA-4086400
Degradation of AXIN R-HSA-4641257
HIV Infection R-HSA-162906
Ub-specific processing proteases R-HSA-5689880
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK family signaling cascades R-HSA-5683057
Antigen processing-Cross presentation R-HSA-1236975
Deubiquitination R-HSA-5688426
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cellular responses to stimuli R-HSA-8953897
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication R-HSA-69306
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
Axon guidance R-HSA-422475
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Independent DNA Damage Response R-HSA-69610
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of DVL R-HSA-4641258
Metabolism of polyamines R-HSA-351202
Downstream TCR signaling R-HSA-202424
Interleukin-1 signaling R-HSA-9020702
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Post-translational protein modification R-HSA-597592
Gene expression (Transcription) R-HSA-74160
Cell Cycle R-HSA-1640170
G2/M Checkpoints R-HSA-69481
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of polyamines R-HSA-351202
Mitotic G2-G2/M phases R-HSA-453274
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Stabilization of p53 R-HSA-69541
Nervous system development R-HSA-9675108
Signaling by Interleukins R-HSA-449147
Regulation of PTEN stability and activity R-HSA-8948751
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Neddylation R-HSA-8951664
Interleukin-1 family signaling R-HSA-446652
C-type lectin receptors (CLRs) R-HSA-5621481
Assembly of the pre-replicative complex R-HSA-68867
Host Interactions of HIV factors R-HSA-162909
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Programmed Cell Death R-HSA-5357801
Separation of Sister Chromatids R-HSA-2467813
Cellular responses to stimuli R-HSA-8953897
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by NOTCH4 R-HSA-9013694
Immune System R-HSA-168256
PTEN Regulation R-HSA-6807070
Regulation of RAS by GAPs R-HSA-5658442
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Negative regulation of NOTCH4 signaling R-HSA-9604323
Axon guidance R-HSA-422475
RNA Polymerase II Transcription R-HSA-73857
Asymmetric localization of PCP proteins R-HSA-4608870
Nuclear events mediated by NFE2L2 R-HSA-9759194
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular response to chemical stress R-HSA-9711123
Gene expression (Transcription) R-HSA-74160
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle, Mitotic R-HSA-69278
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G1/S Transition R-HSA-69206
Metabolism of RNA R-HSA-8953854
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of DVL R-HSA-4641258
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent DNA Damage Response R-HSA-69610
Infectious disease R-HSA-5663205
KEAP1-NFE2L2 pathway R-HSA-9755511
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by WNT R-HSA-195721
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'on' state R-HSA-5632684
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transport of small molecules R-HSA-382551
Orc1 removal from chromatin R-HSA-68949
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Dependent G1 DNA Damage Response R-HSA-69563
HIV Infection R-HSA-162906
Signaling by NOTCH R-HSA-157118
Metabolism R-HSA-1430728
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX3 expression and activity R-HSA-8941858
MAPK1/MAPK3 signaling R-HSA-5684996
Vif-mediated degradation of APOBEC3G R-HSA-180585
M Phase R-HSA-68886
DNA Replication R-HSA-69306
Synthesis of DNA R-HSA-69239
Interleukin-1 signaling R-HSA-9020702
Apoptosis R-HSA-109581
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCF dependent signaling in response to WNT R-HSA-201681
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of AXIN R-HSA-4641257
ABC-family proteins mediated transport R-HSA-382556
Generic Transcription Pathway R-HSA-212436
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stress R-HSA-2262752
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of Apoptosis R-HSA-169911
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
G2/M Transition R-HSA-69275
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Hedgehog R-HSA-5358351
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin E associated events during G1/S transition R-HSA-69202
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI2 by the proteasome R-HSA-5610783
RAF/MAP kinase cascade R-HSA-5673001
Cellular response to hypoxia R-HSA-1234174
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX1 R-HSA-8878171
Adaptive Immune System R-HSA-1280218
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ABC transporter disorders R-HSA-5619084
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
Downstream TCR signaling R-HSA-202424
Hedgehog ligand biogenesis R-HSA-5358346
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PCP/CE pathway R-HSA-4086400
TCR signaling R-HSA-202403
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ub-specific processing proteases R-HSA-5689880
Hedgehog 'off' state R-HSA-5610787
Cell Cycle Checkpoints R-HSA-69620
Mitotic Metaphase and Anaphase R-HSA-2555396
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Assembly of the pre-replicative complex R-HSA-68867
ER-Phagosome pathway R-HSA-1236974
Defective CFTR causes cystic fibrosis R-HSA-5678895
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of amino acids and derivatives R-HSA-71291
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Infectious disease R-HSA-5663205
Hedgehog 'off' state R-HSA-5610787
G2/M Checkpoints R-HSA-69481
Downstream TCR signaling R-HSA-202424
Deubiquitination R-HSA-5688426
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX3 R-HSA-8878159
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stimuli R-HSA-8953897
Immune System R-HSA-168256
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCR signaling R-HSA-202403
MAPK family signaling cascades R-HSA-5683057
Neddylation R-HSA-8951664
Axon guidance R-HSA-422475
Metabolism of proteins R-HSA-392499
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RAS by GAPs R-HSA-5658442
UCH proteinases R-HSA-5689603
Cellular response to chemical stress R-HSA-9711123
Asymmetric localization of PCP proteins R-HSA-4608870
Innate Immune System R-HSA-168249
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Separation of Sister Chromatids R-HSA-2467813
Post-translational protein modification R-HSA-597592
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of polyamines R-HSA-351202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
PCP/CE pathway R-HSA-4086400
ABC transporter disorders R-HSA-5619084
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 signaling R-HSA-9020702
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of PTEN stability and activity R-HSA-8948751
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog 'on' state R-HSA-5632684
Intracellular signaling by second messengers R-HSA-9006925
Regulation of mitotic cell cycle R-HSA-453276
HIV Infection R-HSA-162906
Adaptive Immune System R-HSA-1280218
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
FCERI mediated NF-kB activation R-HSA-2871837
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of expression of SLITs and ROBOs R-HSA-9010553
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Disease R-HSA-1643685
Disorders of transmembrane transporters R-HSA-5619115
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of RNA R-HSA-8953854
Hh mutants are degraded by ERAD R-HSA-5362768
Ub-specific processing proteases R-HSA-5689880
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by ROBO receptors R-HSA-376176
G1/S DNA Damage Checkpoints R-HSA-69615
Cytokine Signaling in Immune system R-HSA-1280215
DNA Replication R-HSA-69306
Cell Cycle, Mitotic R-HSA-69278
Stabilization of p53 R-HSA-69541
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Anaphase R-HSA-68882
M Phase R-HSA-68886
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Interleukins R-HSA-449147
Degradation of DVL R-HSA-4641258
Programmed Cell Death R-HSA-5357801
Degradation of AXIN R-HSA-4641257
Beta-catenin independent WNT signaling R-HSA-3858494
Negative regulation of NOTCH4 signaling R-HSA-9604323
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Dependent G1 DNA Damage Response R-HSA-69563
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transport of small molecules R-HSA-382551
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
MAPK6/MAPK4 signaling R-HSA-5687128
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by NOTCH R-HSA-157118
PTEN Regulation R-HSA-6807070
Synthesis of DNA R-HSA-69239
Switching of origins to a post-replicative state R-HSA-69052
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RAF/MAP kinase cascade R-HSA-5673001
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G1/S Transition R-HSA-69206
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
CLEC7A (Dectin-1) signaling R-HSA-5607764
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signaling by WNT R-HSA-195721
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G2/M Transition R-HSA-69275
C-type lectin receptors (CLRs) R-HSA-5621481
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by Hedgehog R-HSA-5358351
Nuclear events mediated by NFE2L2 R-HSA-9759194
Antigen processing-Cross presentation R-HSA-1236975
RNA Polymerase II Transcription R-HSA-73857
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of RUNX2 expression and activity R-HSA-8939902
Developmental Biology R-HSA-1266738
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
UCH proteinases R-HSA-5689603
Signaling by Interleukins R-HSA-449147
Ub-specific processing proteases R-HSA-5689880
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Interleukin-1 family signaling R-HSA-446652
Nervous system development R-HSA-9675108
Vpu mediated degradation of CD4 R-HSA-180534
TCR signaling R-HSA-202403
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by NOTCH4 R-HSA-9013694
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of RUNX3 expression and activity R-HSA-8941858
DNA Replication R-HSA-69306
Mitotic Anaphase R-HSA-68882
Cellular response to hypoxia R-HSA-1234174
Neddylation R-HSA-8951664
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Generic Transcription Pathway R-HSA-212436
G2/M Checkpoints R-HSA-69481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Gene expression (Transcription) R-HSA-74160
Regulation of mitotic cell cycle R-HSA-453276
Class I MHC mediated antigen processing & presentation R-HSA-983169
ER-Phagosome pathway R-HSA-1236974
Apoptosis R-HSA-109581
Developmental Biology R-HSA-1266738
Activation of NF-kappaB in B cells R-HSA-1169091
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI2 by the proteasome R-HSA-5610783
MAPK family signaling cascades R-HSA-5683057
PCP/CE pathway R-HSA-4086400
Deubiquitination R-HSA-5688426
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stimuli R-HSA-8953897
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Orc1 removal from chromatin R-HSA-68949
RNA Polymerase II Transcription R-HSA-73857
S Phase R-HSA-69242
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
Vif-mediated degradation of APOBEC3G R-HSA-180585
Stabilization of p53 R-HSA-69541
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
MAPK6/MAPK4 signaling R-HSA-5687128
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX3 R-HSA-8878159
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RUNX2 expression and activity R-HSA-8939902
Infectious disease R-HSA-5663205
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
FCERI mediated NF-kB activation R-HSA-2871837
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of proteins R-HSA-392499
PTEN Regulation R-HSA-6807070
HIV Infection R-HSA-162906
Degradation of AXIN R-HSA-4641257
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Independent DNA Damage Response R-HSA-69610
G1/S Transition R-HSA-69206
Post-translational protein modification R-HSA-597592
Cell Cycle Checkpoints R-HSA-69620
Programmed Cell Death R-HSA-5357801
Cellular responses to stress R-HSA-2262752
Disease R-HSA-1643685
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of RNA R-HSA-8953854
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cytokine Signaling in Immune system R-HSA-1280215
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX2 R-HSA-8878166
Synthesis of DNA R-HSA-69239
Downstream TCR signaling R-HSA-202424
Regulation of Apoptosis R-HSA-169911
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
KEAP1-NFE2L2 pathway R-HSA-9755511
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'on' state R-HSA-5632684
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
ABC transporter disorders R-HSA-5619084
Transport of small molecules R-HSA-382551
MAPK1/MAPK3 signaling R-HSA-5684996
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by NOTCH R-HSA-157118
Mitotic G1 phase and G1/S transition R-HSA-453279
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Disorders of transmembrane transporters R-HSA-5619115
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
Antigen processing-Cross presentation R-HSA-1236975
Hh mutants are degraded by ERAD R-HSA-5362768
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of RAS by GAPs R-HSA-5658442
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Interleukin-1 signaling R-HSA-9020702
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by WNT R-HSA-195721
Innate Immune System R-HSA-168249
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Immune System R-HSA-168256
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular response to chemical stress R-HSA-9711123
Signaling by ROBO receptors R-HSA-376176
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RAF/MAP kinase cascade R-HSA-5673001
G2/M Transition R-HSA-69275
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Adaptive Immune System R-HSA-1280218
Cyclin E associated events during G1/S transition R-HSA-69202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by Hedgehog R-HSA-5358351
Assembly of the pre-replicative complex R-HSA-68867
Degradation of GLI1 by the proteasome R-HSA-5610780
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of DVL R-HSA-4641258
ABC-family proteins mediated transport R-HSA-382556
S Phase R-HSA-69242
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by NOTCH4 R-HSA-9013694
Vpu mediated degradation of CD4 R-HSA-180534
Transcriptional regulation by RUNX1 R-HSA-8878171
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Synthesis of DNA R-HSA-69239
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S Transition R-HSA-69206
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
Metabolism of polyamines R-HSA-351202
FCERI mediated NF-kB activation R-HSA-2871837
Assembly of the pre-replicative complex R-HSA-68867
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Antigen processing-Cross presentation R-HSA-1236975
Interleukin-1 signaling R-HSA-9020702
MAPK1/MAPK3 signaling R-HSA-5684996
Beta-catenin independent WNT signaling R-HSA-3858494
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ub-specific processing proteases R-HSA-5689880
Nervous system development R-HSA-9675108
Regulation of PTEN stability and activity R-HSA-8948751
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of beta-catenin by the destruction complex R-HSA-195253
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Gene expression (Transcription) R-HSA-74160
Neddylation R-HSA-8951664
Axon guidance R-HSA-422475
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Deubiquitination R-HSA-5688426
Cell Cycle, Mitotic R-HSA-69278
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stimuli R-HSA-8953897
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
Mitotic Metaphase and Anaphase R-HSA-2555396
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
Regulation of mitotic cell cycle R-HSA-453276
Separation of Sister Chromatids R-HSA-2467813
p53-Independent DNA Damage Response R-HSA-69610
Regulation of Apoptosis R-HSA-169911
Class I MHC mediated antigen processing & presentation R-HSA-983169
Generic Transcription Pathway R-HSA-212436
Cell Cycle Checkpoints R-HSA-69620
HIV Infection R-HSA-162906
Programmed Cell Death R-HSA-5357801
G1/S DNA Damage Checkpoints R-HSA-69615
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
Degradation of DVL R-HSA-4641258
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RAF/MAP kinase cascade R-HSA-5673001
Adaptive Immune System R-HSA-1280218
Hedgehog 'off' state R-HSA-5610787
Signaling by ROBO receptors R-HSA-376176
ABC transporter disorders R-HSA-5619084
MAPK6/MAPK4 signaling R-HSA-5687128
M Phase R-HSA-68886
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic Anaphase R-HSA-68882
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
DNA Replication Pre-Initiation R-HSA-69002
MAPK family signaling cascades R-HSA-5683057
Metabolism of RNA R-HSA-8953854
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RAS by GAPs R-HSA-5658442
TCF dependent signaling in response to WNT R-HSA-201681
Orc1 removal from chromatin R-HSA-68949
Asymmetric localization of PCP proteins R-HSA-4608870
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
G2/M Checkpoints R-HSA-69481
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of amino acids and derivatives R-HSA-71291
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'on' state R-HSA-5632684
Infectious disease R-HSA-5663205
Negative regulation of NOTCH4 signaling R-HSA-9604323
Defective CFTR causes cystic fibrosis R-HSA-5678895
ER-Phagosome pathway R-HSA-1236974
Disease R-HSA-1643685
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PTEN Regulation R-HSA-6807070
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
UCH proteinases R-HSA-5689603
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog ligand biogenesis R-HSA-5358346
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH R-HSA-157118
TCR signaling R-HSA-202403
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle R-HSA-1640170
Mitotic G2-G2/M phases R-HSA-453274
Immune System R-HSA-168256
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Apoptosis R-HSA-109581
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Cellular response to chemical stress R-HSA-9711123
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Intracellular signaling by second messengers R-HSA-9006925
Degradation of AXIN R-HSA-4641257
Signaling by WNT R-HSA-195721
Signaling by Interleukins R-HSA-449147
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX2 R-HSA-8878166
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Switching of origins to a post-replicative state R-HSA-69052
KEAP1-NFE2L2 pathway R-HSA-9755511
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Developmental Biology R-HSA-1266738
G2/M Transition R-HSA-69275
Cellular response to hypoxia R-HSA-1234174
Stabilization of p53 R-HSA-69541
Degradation of GLI1 by the proteasome R-HSA-5610780
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vif-mediated degradation of APOBEC3G R-HSA-180585
DNA Replication R-HSA-69306
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S DNA Damage Checkpoints R-HSA-69615
Negative regulation of NOTCH4 signaling R-HSA-9604323
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PIP3 activates AKT signaling R-HSA-1257604
S Phase R-HSA-69242
Adaptive Immune System R-HSA-1280218
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
Cellular responses to stress R-HSA-2262752
ER-Phagosome pathway R-HSA-1236974
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication Pre-Initiation R-HSA-69002
TCF dependent signaling in response to WNT R-HSA-201681
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stimuli R-HSA-8953897
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Checkpoints R-HSA-69481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by NOTCH R-HSA-157118
TCR signaling R-HSA-202403
Nervous system development R-HSA-9675108
RAF/MAP kinase cascade R-HSA-5673001
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of proteins R-HSA-392499
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
Innate Immune System R-HSA-168249
p53-Independent DNA Damage Response R-HSA-69610
Orc1 removal from chromatin R-HSA-68949
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of mitotic cell cycle R-HSA-453276
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Cellular response to hypoxia R-HSA-1234174
Cellular response to chemical stress R-HSA-9711123
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of Apoptosis R-HSA-169911
Disorders of transmembrane transporters R-HSA-5619115
G2/M Transition R-HSA-69275
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic G2-G2/M phases R-HSA-453274
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Assembly of the pre-replicative complex R-HSA-68867
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK6/MAPK4 signaling R-HSA-5687128
Defective CFTR causes cystic fibrosis R-HSA-5678895
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Post-translational protein modification R-HSA-597592
Stabilization of p53 R-HSA-69541
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Axon guidance R-HSA-422475
MAPK1/MAPK3 signaling R-HSA-5684996
PTEN Regulation R-HSA-6807070
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH4 R-HSA-9013694
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Apoptosis R-HSA-109581
Programmed Cell Death R-HSA-5357801
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Degradation of GLI2 by the proteasome R-HSA-5610783
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of RAS by GAPs R-HSA-5658442
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Transcriptional regulation by RUNX2 R-HSA-8878166
Hedgehog 'on' state R-HSA-5632684
FCERI mediated NF-kB activation R-HSA-2871837
Deubiquitination R-HSA-5688426
Hh mutants are degraded by ERAD R-HSA-5362768
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of GLI1 by the proteasome R-HSA-5610780
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism R-HSA-1430728
Infectious disease R-HSA-5663205
DNA Replication R-HSA-69306
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by Hedgehog R-HSA-5358351
Cyclin E associated events during G1/S transition R-HSA-69202
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Host Interactions of HIV factors R-HSA-162909
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Immune System R-HSA-168256
G1/S Transition R-HSA-69206
HIV Infection R-HSA-162906
ABC-family proteins mediated transport R-HSA-382556
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle, Mitotic R-HSA-69278
Downstream TCR signaling R-HSA-202424
Transport of small molecules R-HSA-382551
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Interleukin-1 signaling R-HSA-9020702
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of amino acids and derivatives R-HSA-71291
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Anaphase R-HSA-68882
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Mitotic G1 phase and G1/S transition R-HSA-453279
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of AXIN R-HSA-4641257
Degradation of DVL R-HSA-4641258
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Interleukin-1 family signaling R-HSA-446652
Hedgehog ligand biogenesis R-HSA-5358346
Separation of Sister Chromatids R-HSA-2467813
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hh mutants abrogate ligand secretion R-HSA-5387390
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RNA Polymerase II Transcription R-HSA-73857
PCP/CE pathway R-HSA-4086400
ABC transporter disorders R-HSA-5619084
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Separation of Sister Chromatids R-HSA-2467813
Neddylation R-HSA-8951664
Regulation of Apoptosis R-HSA-169911
Cell Cycle R-HSA-1640170
Regulation of RAS by GAPs R-HSA-5658442
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TCR signaling R-HSA-202403
HIV Infection R-HSA-162906
Nervous system development R-HSA-9675108
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 signaling R-HSA-9020702
Signaling by NOTCH4 R-HSA-9013694
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Infectious disease R-HSA-5663205
Mitotic G1 phase and G1/S transition R-HSA-453279
MAPK6/MAPK4 signaling R-HSA-5687128
Programmed Cell Death R-HSA-5357801
Hedgehog ligand biogenesis R-HSA-5358346
ABC-family proteins mediated transport R-HSA-382556
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by Hedgehog R-HSA-5358351
Adaptive Immune System R-HSA-1280218
Gene expression (Transcription) R-HSA-74160
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
DNA Replication R-HSA-69306
Activation of NF-kappaB in B cells R-HSA-1169091
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
Interleukin-1 family signaling R-HSA-446652
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of proteins R-HSA-392499
G1/S Transition R-HSA-69206
Disease R-HSA-1643685
Cellular response to chemical stress R-HSA-9711123
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic Metaphase and Anaphase R-HSA-2555396
Stabilization of p53 R-HSA-69541
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hedgehog 'off' state R-HSA-5610787
Vpu mediated degradation of CD4 R-HSA-180534
Antigen processing-Cross presentation R-HSA-1236975
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Apoptosis R-HSA-109581
PCP/CE pathway R-HSA-4086400
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of beta-catenin by the destruction complex R-HSA-195253
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Post-translational protein modification R-HSA-597592
Axon guidance R-HSA-422475
Signaling by Interleukins R-HSA-449147
Hh mutants abrogate ligand secretion R-HSA-5387390
RNA Polymerase II Transcription R-HSA-73857
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Defective CFTR causes cystic fibrosis R-HSA-5678895
Synthesis of DNA R-HSA-69239
Assembly of the pre-replicative complex R-HSA-68867
Asymmetric localization of PCP proteins R-HSA-4608870
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ABC transporter disorders R-HSA-5619084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
M Phase R-HSA-68886
Orc1 removal from chromatin R-HSA-68949
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G2/M Checkpoints R-HSA-69481
Mitotic G2-G2/M phases R-HSA-453274
p53-Independent DNA Damage Response R-HSA-69610
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Host Interactions of HIV factors R-HSA-162909
TCF dependent signaling in response to WNT R-HSA-201681
Cellular response to hypoxia R-HSA-1234174
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of RUNX3 expression and activity R-HSA-8941858
DNA Replication Pre-Initiation R-HSA-69002
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by the B Cell Receptor (BCR) R-HSA-983705
S Phase R-HSA-69242
Developmental Biology R-HSA-1266738
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic Anaphase R-HSA-68882
Disorders of transmembrane transporters R-HSA-5619115
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signal Transduction R-HSA-162582
Metabolism R-HSA-1430728
Signaling by ROBO receptors R-HSA-376176
FCERI mediated NF-kB activation R-HSA-2871837
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cytokine Signaling in Immune system R-HSA-1280215
C-type lectin receptors (CLRs) R-HSA-5621481
UCH proteinases R-HSA-5689603
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK family signaling cascades R-HSA-5683057
Innate Immune System R-HSA-168249
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of RNA R-HSA-8953854
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
Signaling by NOTCH R-HSA-157118
G2/M Transition R-HSA-69275
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK1/MAPK3 signaling R-HSA-5684996
Vif-mediated degradation of APOBEC3G R-HSA-180585
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ub-specific processing proteases R-HSA-5689880
Downstream TCR signaling R-HSA-202424
Switching of origins to a post-replicative state R-HSA-69052
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Dependent G1 DNA Damage Response R-HSA-69563
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stimuli R-HSA-8953897
ER-Phagosome pathway R-HSA-1236974
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of PTEN stability and activity R-HSA-8948751
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of AXIN R-HSA-4641257
PTEN Regulation R-HSA-6807070
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
G1/S DNA Damage Checkpoints R-HSA-69615
Transport of small molecules R-HSA-382551
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of polyamines R-HSA-351202
Degradation of DVL R-HSA-4641258
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of polyamines R-HSA-351202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Beta-catenin independent WNT signaling R-HSA-3858494
Nervous system development R-HSA-9675108
Downstream TCR signaling R-HSA-202424
Axon guidance R-HSA-422475
G1/S Transition R-HSA-69206
Synthesis of DNA R-HSA-69239
PTEN Regulation R-HSA-6807070
Developmental Biology R-HSA-1266738
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Defective CFTR causes cystic fibrosis R-HSA-5678895
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 signaling R-HSA-9020702
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RAF/MAP kinase cascade R-HSA-5673001
Cellular responses to stimuli R-HSA-8953897
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Switching of origins to a post-replicative state R-HSA-69052
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Class I MHC mediated antigen processing & presentation R-HSA-983169
C-type lectin receptors (CLRs) R-HSA-5621481
Asymmetric localization of PCP proteins R-HSA-4608870
G2/M Checkpoints R-HSA-69481
MAPK1/MAPK3 signaling R-HSA-5684996
Immune System R-HSA-168256
Disease R-HSA-1643685
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by NOTCH R-HSA-157118
Infectious disease R-HSA-5663205
M Phase R-HSA-68886
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Gene expression (Transcription) R-HSA-74160
Signaling by WNT R-HSA-195721
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cell Cycle R-HSA-1640170
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Separation of Sister Chromatids R-HSA-2467813
Hh mutants are degraded by ERAD R-HSA-5362768
S Phase R-HSA-69242
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of AXIN R-HSA-4641257
FCERI mediated NF-kB activation R-HSA-2871837
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RNA Polymerase II Transcription R-HSA-73857
Hedgehog 'on' state R-HSA-5632684
Metabolism of RNA R-HSA-8953854
PCP/CE pathway R-HSA-4086400
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of RAS by GAPs R-HSA-5658442
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of RUNX3 expression and activity R-HSA-8941858
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stress R-HSA-2262752
Vpu mediated degradation of CD4 R-HSA-180534
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism R-HSA-1430728
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Ub-specific processing proteases R-HSA-5689880
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic Anaphase R-HSA-68882
MAPK family signaling cascades R-HSA-5683057
Regulation of RUNX2 expression and activity R-HSA-8939902
Deubiquitination R-HSA-5688426
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
Cytokine Signaling in Immune system R-HSA-1280215
Negative regulation of NOTCH4 signaling R-HSA-9604323
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Intracellular signaling by second messengers R-HSA-9006925
Degradation of DVL R-HSA-4641258
Neddylation R-HSA-8951664
Orc1 removal from chromatin R-HSA-68949
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH4 R-HSA-9013694
Metabolism of proteins R-HSA-392499
HIV Infection R-HSA-162906
Signaling by Hedgehog R-HSA-5358351
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Post-translational protein modification R-HSA-597592
ABC-family proteins mediated transport R-HSA-382556
Assembly of the pre-replicative complex R-HSA-68867
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Programmed Cell Death R-HSA-5357801
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog 'off' state R-HSA-5610787
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of GLI1 by the proteasome R-HSA-5610780
ER-Phagosome pathway R-HSA-1236974
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cellular response to chemical stress R-HSA-9711123
UCH proteinases R-HSA-5689603
DNA Replication R-HSA-69306
Signaling by ROBO receptors R-HSA-376176
Disorders of transmembrane transporters R-HSA-5619115
Interleukin-1 family signaling R-HSA-446652
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle Checkpoints R-HSA-69620
Degradation of GLI2 by the proteasome R-HSA-5610783
Cellular response to hypoxia R-HSA-1234174
Signaling by Interleukins R-HSA-449147
DNA Replication Pre-Initiation R-HSA-69002
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing-Cross presentation R-HSA-1236975
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of beta-catenin by the destruction complex R-HSA-195253
TCR signaling R-HSA-202403
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signal Transduction R-HSA-162582
G2/M Transition R-HSA-69275
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FCERI mediated NF-kB activation R-HSA-2871837
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by WNT R-HSA-195721
Metabolism of polyamines R-HSA-351202
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of GLI1 by the proteasome R-HSA-5610780
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
Intracellular signaling by second messengers R-HSA-9006925
Nuclear events mediated by NFE2L2 R-HSA-9759194
G1/S Transition R-HSA-69206
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Asymmetric localization of PCP proteins R-HSA-4608870
G1/S DNA Damage Checkpoints R-HSA-69615
Synthesis of DNA R-HSA-69239
Regulation of PTEN stability and activity R-HSA-8948751
Assembly of the pre-replicative complex R-HSA-68867
Hedgehog 'on' state R-HSA-5632684
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Replication R-HSA-69306
RAF/MAP kinase cascade R-HSA-5673001
Regulation of RAS by GAPs R-HSA-5658442
Cellular responses to stimuli R-HSA-8953897
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
Infectious disease R-HSA-5663205
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Independent DNA Damage Response R-HSA-69610
PIP3 activates AKT signaling R-HSA-1257604
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX2 R-HSA-8878166
Hedgehog 'off' state R-HSA-5610787
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
Degradation of AXIN R-HSA-4641257
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
Gene expression (Transcription) R-HSA-74160
Programmed Cell Death R-HSA-5357801
G2/M Checkpoints R-HSA-69481
G2/M Transition R-HSA-69275
Separation of Sister Chromatids R-HSA-2467813
PTEN Regulation R-HSA-6807070
Switching of origins to a post-replicative state R-HSA-69052
Degradation of GLI2 by the proteasome R-HSA-5610783
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cyclin E associated events during G1/S transition R-HSA-69202
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of Apoptosis R-HSA-169911
Degradation of beta-catenin by the destruction complex R-HSA-195253
Mitotic G1 phase and G1/S transition R-HSA-453279
ABC-family proteins mediated transport R-HSA-382556
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by NOTCH4 R-HSA-9013694
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX3 R-HSA-8878159
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of RNA R-HSA-8953854
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TCR signaling R-HSA-202403
Interleukin-1 family signaling R-HSA-446652
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Apoptosis R-HSA-109581
UCH proteinases R-HSA-5689603
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
MAPK1/MAPK3 signaling R-HSA-5684996
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
HIV Infection R-HSA-162906
Degradation of DVL R-HSA-4641258
Regulation of expression of SLITs and ROBOs R-HSA-9010553
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to hypoxia R-HSA-1234174
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Innate Immune System R-HSA-168249
Cellular responses to stress R-HSA-2262752
Neddylation R-HSA-8951664
Interleukin-1 signaling R-HSA-9020702
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of RUNX3 expression and activity R-HSA-8941858
Adaptive Immune System R-HSA-1280218
Regulation of RUNX2 expression and activity R-HSA-8939902
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle, Mitotic R-HSA-69278
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Orc1 removal from chromatin R-HSA-68949
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cellular response to chemical stress R-HSA-9711123
Transport of small molecules R-HSA-382551
PCP/CE pathway R-HSA-4086400
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
Host Interactions of HIV factors R-HSA-162909
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signal Transduction R-HSA-162582
Metabolism R-HSA-1430728
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
Metabolism of amino acids and derivatives R-HSA-71291
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Antigen processing-Cross presentation R-HSA-1236975
Signaling by the B Cell Receptor (BCR) R-HSA-983705
C-type lectin receptors (CLRs) R-HSA-5621481
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Beta-catenin independent WNT signaling R-HSA-3858494
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ub-specific processing proteases R-HSA-5689880
Signaling by Hedgehog R-HSA-5358351
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by ROBO receptors R-HSA-376176
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Nervous system development R-HSA-9675108
Hh mutants are degraded by ERAD R-HSA-5362768
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Downstream TCR signaling R-HSA-202424
MAPK6/MAPK4 signaling R-HSA-5687128
Hh mutants abrogate ligand secretion R-HSA-5387390
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of mitotic cell cycle R-HSA-453276
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
ER-Phagosome pathway R-HSA-1236974
MAPK family signaling cascades R-HSA-5683057
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372

Expression Atlas ENSG00000041357
NCBI gene (formerly Entrezgene) 5685
GeneCards 9533
HGNC Symbol HGNC:9533
MIM gene 176846
UniProtKB Gene Name P25789
WikiGene 5685
Gene: PSMA8
Ensembl ID : ENSG00000154611
Description: proteasome 20S subunit alpha 8
Gene Synonyms: MGC26605,PSMA7L
6 APIs:
197 Possible Orthologues:

S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by WNT R-HSA-195721
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
TCF dependent signaling in response to WNT R-HSA-201681
Synthesis of DNA R-HSA-69239
NIK-->noncanonical NF-kB signaling R-HSA-5676590
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
FCERI mediated NF-kB activation R-HSA-2871837
Cellular response to hypoxia R-HSA-1234174
Regulation of RAS by GAPs R-HSA-5658442
Innate Immune System R-HSA-168249
Metabolism of amino acids and derivatives R-HSA-71291
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of DVL R-HSA-4641258
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Antigen processing-Cross presentation R-HSA-1236975
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
CLEC7A (Dectin-1) signaling R-HSA-5607764
UCH proteinases R-HSA-5689603
DNA Replication R-HSA-69306
Deubiquitination R-HSA-5688426
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic Anaphase R-HSA-68882
Apoptosis R-HSA-109581
Metabolism of RNA R-HSA-8953854
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
ABC-family proteins mediated transport R-HSA-382556
Cytokine Signaling in Immune system R-HSA-1280215
Transport of small molecules R-HSA-382551
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Separation of Sister Chromatids R-HSA-2467813
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Post-translational protein modification R-HSA-597592
Degradation of GLI2 by the proteasome R-HSA-5610783
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of polyamines R-HSA-351202
ABC transporter disorders R-HSA-5619084
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK family signaling cascades R-HSA-5683057
Hh mutants abrogate ligand secretion R-HSA-5387390
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
G2/M Transition R-HSA-69275
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
Hedgehog ligand biogenesis R-HSA-5358346
Activation of NF-kappaB in B cells R-HSA-1169091
Developmental Biology R-HSA-1266738
Neddylation R-HSA-8951664
Infectious disease R-HSA-5663205
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RUNX2 expression and activity R-HSA-8939902
Defective CFTR causes cystic fibrosis R-HSA-5678895
Axon guidance R-HSA-422475
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Hedgehog 'off' state R-HSA-5610787
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Asymmetric localization of PCP proteins R-HSA-4608870
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
Orc1 removal from chromatin R-HSA-68949
Host Interactions of HIV factors R-HSA-162909
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent DNA Damage Response R-HSA-69610
Immune System R-HSA-168256
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Signaling by ROBO receptors R-HSA-376176
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX2 R-HSA-8878166
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by Hedgehog R-HSA-5358351
G2/M Checkpoints R-HSA-69481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of Apoptosis R-HSA-169911
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Interleukins R-HSA-449147
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
Stabilization of p53 R-HSA-69541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
M Phase R-HSA-68886
G1/S DNA Damage Checkpoints R-HSA-69615
Hedgehog 'on' state R-HSA-5632684
Cellular response to chemical stress R-HSA-9711123
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
PTEN Regulation R-HSA-6807070
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX1 R-HSA-8878171
PIP3 activates AKT signaling R-HSA-1257604
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ub-specific processing proteases R-HSA-5689880
Infectious disease R-HSA-5663205
Downstream TCR signaling R-HSA-202424
Ub-specific processing proteases R-HSA-5689880
Signaling by ROBO receptors R-HSA-376176
Disease R-HSA-1643685
Metabolism of polyamines R-HSA-351202
Nervous system development R-HSA-9675108
Antigen processing-Cross presentation R-HSA-1236975
Synthesis of DNA R-HSA-69239
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stress R-HSA-2262752
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
PCP/CE pathway R-HSA-4086400
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by Interleukins R-HSA-449147
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RAS by GAPs R-HSA-5658442
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Deubiquitination R-HSA-5688426
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Host Interactions of HIV factors R-HSA-162909
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic Metaphase and Anaphase R-HSA-2555396
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
M Phase R-HSA-68886
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G2/M Checkpoints R-HSA-69481
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic G2-G2/M phases R-HSA-453274
Innate Immune System R-HSA-168249
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by WNT R-HSA-195721
Cell Cycle R-HSA-1640170
Programmed Cell Death R-HSA-5357801
MAPK family signaling cascades R-HSA-5683057
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ABC transporter disorders R-HSA-5619084
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
Interleukin-1 signaling R-HSA-9020702
Regulation of mitotic cell cycle R-HSA-453276
Cellular response to chemical stress R-HSA-9711123
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular response to hypoxia R-HSA-1234174
G2/M Transition R-HSA-69275
RAF/MAP kinase cascade R-HSA-5673001
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism R-HSA-1430728
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
DNA Replication R-HSA-69306
ABC-family proteins mediated transport R-HSA-382556
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants abrogate ligand secretion R-HSA-5387390
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Stabilization of p53 R-HSA-69541
Degradation of AXIN R-HSA-4641257
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Hedgehog R-HSA-5358351
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX1 R-HSA-8878171
Apoptosis R-HSA-109581
Degradation of beta-catenin by the destruction complex R-HSA-195253
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
ER-Phagosome pathway R-HSA-1236974
CLEC7A (Dectin-1) signaling R-HSA-5607764
RNA Polymerase II Transcription R-HSA-73857
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1 DNA Damage Response R-HSA-69563
PTEN Regulation R-HSA-6807070
Regulation of PTEN stability and activity R-HSA-8948751
Developmental Biology R-HSA-1266738
Hedgehog 'off' state R-HSA-5610787
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TCF dependent signaling in response to WNT R-HSA-201681
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK6/MAPK4 signaling R-HSA-5687128
HIV Infection R-HSA-162906
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
Intracellular signaling by second messengers R-HSA-9006925
Degradation of DVL R-HSA-4641258
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of Apoptosis R-HSA-169911
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transport of small molecules R-HSA-382551
Hedgehog 'on' state R-HSA-5632684
Hedgehog ligand biogenesis R-HSA-5358346
Generic Transcription Pathway R-HSA-212436
Degradation of GLI2 by the proteasome R-HSA-5610783
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Axon guidance R-HSA-422475
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Mitotic Anaphase R-HSA-68882
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PCP/CE pathway R-HSA-4086400
Activation of NF-kappaB in B cells R-HSA-1169091
Asymmetric localization of PCP proteins R-HSA-4608870
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Disorders of transmembrane transporters R-HSA-5619115
Host Interactions of HIV factors R-HSA-162909
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX2 R-HSA-8878166
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by WNT R-HSA-195721
Post-translational protein modification R-HSA-597592
C-type lectin receptors (CLRs) R-HSA-5621481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'off' state R-HSA-5610787
Metabolism of proteins R-HSA-392499
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by ROBO receptors R-HSA-376176
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX1 R-HSA-8878171
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Dependent G1 DNA Damage Response R-HSA-69563
G2/M Checkpoints R-HSA-69481
HIV Infection R-HSA-162906
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of AXIN R-HSA-4641257
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
Cellular responses to stress R-HSA-2262752
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants abrogate ligand secretion R-HSA-5387390
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
Metabolism of polyamines R-HSA-351202
PTEN Regulation R-HSA-6807070
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Deubiquitination R-HSA-5688426
MAPK1/MAPK3 signaling R-HSA-5684996
Vif-mediated degradation of APOBEC3G R-HSA-180585
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic Anaphase R-HSA-68882
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
Disease R-HSA-1643685
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Programmed Cell Death R-HSA-5357801
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX2 expression and activity R-HSA-8939902
Neddylation R-HSA-8951664
Downstream TCR signaling R-HSA-202424
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
M Phase R-HSA-68886
Interleukin-1 signaling R-HSA-9020702
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
Infectious disease R-HSA-5663205
Separation of Sister Chromatids R-HSA-2467813
Signaling by Hedgehog R-HSA-5358351
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle R-HSA-1640170
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication R-HSA-69306
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to hypoxia R-HSA-1234174
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of Apoptosis R-HSA-169911
Regulation of mitotic cell cycle R-HSA-453276
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Intracellular signaling by second messengers R-HSA-9006925
G2/M Transition R-HSA-69275
Regulation of PTEN stability and activity R-HSA-8948751
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RAS by GAPs R-HSA-5658442
PIP3 activates AKT signaling R-HSA-1257604
Degradation of beta-catenin by the destruction complex R-HSA-195253
ABC-family proteins mediated transport R-HSA-382556
Hedgehog ligand biogenesis R-HSA-5358346
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
UCH proteinases R-HSA-5689603
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Stabilization of p53 R-HSA-69541
G1/S DNA Damage Checkpoints R-HSA-69615
Nervous system development R-HSA-9675108
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'on' state R-HSA-5632684
Developmental Biology R-HSA-1266738
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Axon guidance R-HSA-422475
Switching of origins to a post-replicative state R-HSA-69052
Signal Transduction R-HSA-162582
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ub-specific processing proteases R-HSA-5689880
ER-Phagosome pathway R-HSA-1236974
Cell Cycle Checkpoints R-HSA-69620
Vpu mediated degradation of CD4 R-HSA-180534
RAF/MAP kinase cascade R-HSA-5673001
TCR signaling R-HSA-202403
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 family signaling R-HSA-446652
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PCP/CE pathway R-HSA-4086400
G1/S DNA Damage Checkpoints R-HSA-69615
Orc1 removal from chromatin R-HSA-68949
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCF dependent signaling in response to WNT R-HSA-201681
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
ER-Phagosome pathway R-HSA-1236974
Adaptive Immune System R-HSA-1280218
Antigen processing-Cross presentation R-HSA-1236975
Beta-catenin independent WNT signaling R-HSA-3858494
Vif-mediated degradation of APOBEC3G R-HSA-180585
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 family signaling R-HSA-446652
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Independent DNA Damage Response R-HSA-69610
RAF/MAP kinase cascade R-HSA-5673001
Regulation of RAS by GAPs R-HSA-5658442
Apoptosis R-HSA-109581
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
MAPK family signaling cascades R-HSA-5683057
CLEC7A (Dectin-1) signaling R-HSA-5607764
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'off' state R-HSA-5610787
S Phase R-HSA-69242
Axon guidance R-HSA-422475
Cell Cycle R-HSA-1640170
MAPK1/MAPK3 signaling R-HSA-5684996
ABC transporter disorders R-HSA-5619084
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to chemical stress R-HSA-9711123
Metabolism of polyamines R-HSA-351202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK6/MAPK4 signaling R-HSA-5687128
Deubiquitination R-HSA-5688426
Hh mutants are degraded by ERAD R-HSA-5362768
G2/M Checkpoints R-HSA-69481
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by WNT R-HSA-195721
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ub-specific processing proteases R-HSA-5689880
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signal Transduction R-HSA-162582
Downstream TCR signaling R-HSA-202424
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
Degradation of AXIN R-HSA-4641257
Nervous system development R-HSA-9675108
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TCR signaling R-HSA-202403
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
Transport of small molecules R-HSA-382551
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular responses to stimuli R-HSA-8953897
HIV Infection R-HSA-162906
G2/M Transition R-HSA-69275
ABC-family proteins mediated transport R-HSA-382556
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Innate Immune System R-HSA-168249
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cytokine Signaling in Immune system R-HSA-1280215
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of GLI1 by the proteasome R-HSA-5610780
Programmed Cell Death R-HSA-5357801
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of DVL R-HSA-4641258
Degradation of beta-catenin by the destruction complex R-HSA-195253
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic Metaphase and Anaphase R-HSA-2555396
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX2 R-HSA-8878166
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
PIP3 activates AKT signaling R-HSA-1257604
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Defective CFTR causes cystic fibrosis R-HSA-5678895
Interleukin-1 signaling R-HSA-9020702
Neddylation R-HSA-8951664
Cell Cycle, Mitotic R-HSA-69278
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PTEN Regulation R-HSA-6807070
Hedgehog 'on' state R-HSA-5632684
Post-translational protein modification R-HSA-597592
Separation of Sister Chromatids R-HSA-2467813
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of RNA R-HSA-8953854
Mitotic Anaphase R-HSA-68882
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism R-HSA-1430728
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Developmental Biology R-HSA-1266738
Cellular response to hypoxia R-HSA-1234174
Regulation of PTEN stability and activity R-HSA-8948751
Degradation of GLI2 by the proteasome R-HSA-5610783
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of expression of SLITs and ROBOs R-HSA-9010553
M Phase R-HSA-68886
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication R-HSA-69306
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of amino acids and derivatives R-HSA-71291
Immune System R-HSA-168256
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle Checkpoints R-HSA-69620
PCP/CE pathway R-HSA-4086400
Cell Cycle Checkpoints R-HSA-69620
UCH proteinases R-HSA-5689603
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of polyamines R-HSA-351202
TCR signaling R-HSA-202403
M Phase R-HSA-68886
Infectious disease R-HSA-5663205
Degradation of GLI2 by the proteasome R-HSA-5610783
Separation of Sister Chromatids R-HSA-2467813
Cellular response to hypoxia R-HSA-1234174
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants abrogate ligand secretion R-HSA-5387390
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by ROBO receptors R-HSA-376176
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of amino acids and derivatives R-HSA-71291
S Phase R-HSA-69242
Axon guidance R-HSA-422475
Signaling by Interleukins R-HSA-449147
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic G2-G2/M phases R-HSA-453274
Class I MHC mediated antigen processing & presentation R-HSA-983169
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic Anaphase R-HSA-68882
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle R-HSA-1640170
Degradation of AXIN R-HSA-4641257
G2/M Checkpoints R-HSA-69481
Apoptosis R-HSA-109581
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stimuli R-HSA-8953897
Post-translational protein modification R-HSA-597592
Regulation of mitotic cell cycle R-HSA-453276
Defective CFTR causes cystic fibrosis R-HSA-5678895
G2/M Transition R-HSA-69275
HIV Infection R-HSA-162906
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of PTEN stability and activity R-HSA-8948751
Immune System R-HSA-168256
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Metaphase and Anaphase R-HSA-2555396
Antigen processing-Cross presentation R-HSA-1236975
Interleukin-1 family signaling R-HSA-446652
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
Metabolism R-HSA-1430728
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
ER-Phagosome pathway R-HSA-1236974
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stress R-HSA-2262752
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
Adaptive Immune System R-HSA-1280218
Hedgehog ligand biogenesis R-HSA-5358346
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Gene expression (Transcription) R-HSA-74160
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cytokine Signaling in Immune system R-HSA-1280215
C-type lectin receptors (CLRs) R-HSA-5621481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by WNT R-HSA-195721
Disorders of transmembrane transporters R-HSA-5619115
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Signaling by Hedgehog R-HSA-5358351
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RAS by GAPs R-HSA-5658442
Degradation of DVL R-HSA-4641258
Cellular response to chemical stress R-HSA-9711123
DNA Replication R-HSA-69306
Hh mutants are degraded by ERAD R-HSA-5362768
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
RAF/MAP kinase cascade R-HSA-5673001
Degradation of beta-catenin by the destruction complex R-HSA-195253
MAPK family signaling cascades R-HSA-5683057
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog 'off' state R-HSA-5610787
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
Metabolism of proteins R-HSA-392499
MAPK6/MAPK4 signaling R-HSA-5687128
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
ABC transporter disorders R-HSA-5619084
Generic Transcription Pathway R-HSA-212436
Innate Immune System R-HSA-168249
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Intracellular signaling by second messengers R-HSA-9006925
Downstream TCR signaling R-HSA-202424
Metabolism R-HSA-1430728
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RAS by GAPs R-HSA-5658442
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Switching of origins to a post-replicative state R-HSA-69052
Adaptive Immune System R-HSA-1280218
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Generic Transcription Pathway R-HSA-212436
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Separation of Sister Chromatids R-HSA-2467813
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TCR signaling R-HSA-202403
Interleukin-1 signaling R-HSA-9020702
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic Anaphase R-HSA-68882
UCH proteinases R-HSA-5689603
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of PTEN stability and activity R-HSA-8948751
Ub-specific processing proteases R-HSA-5689880
Deubiquitination R-HSA-5688426
Signaling by Hedgehog R-HSA-5358351
Synthesis of DNA R-HSA-69239
ER-Phagosome pathway R-HSA-1236974
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle Checkpoints R-HSA-69620
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of proteins R-HSA-392499
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Class I MHC mediated antigen processing & presentation R-HSA-983169
Nervous system development R-HSA-9675108
Activation of NF-kappaB in B cells R-HSA-1169091
Infectious disease R-HSA-5663205
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of mitotic cell cycle R-HSA-453276
Downstream TCR signaling R-HSA-202424
KEAP1-NFE2L2 pathway R-HSA-9755511
G2/M Checkpoints R-HSA-69481
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Axon guidance R-HSA-422475
Cell Cycle, Mitotic R-HSA-69278
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PCP/CE pathway R-HSA-4086400
Signaling by WNT R-HSA-195721
Antigen processing-Cross presentation R-HSA-1236975
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
NIK-->noncanonical NF-kB signaling R-HSA-5676590
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle R-HSA-1640170
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hh mutants abrogate ligand secretion R-HSA-5387390
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog 'on' state R-HSA-5632684
Vpu mediated degradation of CD4 R-HSA-180534
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Mitotic Metaphase and Anaphase R-HSA-2555396
Immune System R-HSA-168256
Regulation of Apoptosis R-HSA-169911
Hh mutants are degraded by ERAD R-HSA-5362768
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of AXIN R-HSA-4641257
p53-Independent DNA Damage Response R-HSA-69610
Host Interactions of HIV factors R-HSA-162909
RNA Polymerase II Transcription R-HSA-73857
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Apoptosis R-HSA-109581
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of polyamines R-HSA-351202
p53-Dependent G1 DNA Damage Response R-HSA-69563
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
Post-translational protein modification R-HSA-597592
Metabolism of amino acids and derivatives R-HSA-71291
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of DVL R-HSA-4641258
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
HIV Infection R-HSA-162906
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
Disease R-HSA-1643685
Programmed Cell Death R-HSA-5357801
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular response to hypoxia R-HSA-1234174
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Stabilization of p53 R-HSA-69541
Gene expression (Transcription) R-HSA-74160
Transport of small molecules R-HSA-382551
Disorders of transmembrane transporters R-HSA-5619115
Cellular response to chemical stress R-HSA-9711123
Intracellular signaling by second messengers R-HSA-9006925
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of proteins R-HSA-392499
Cellular response to hypoxia R-HSA-1234174
Nervous system development R-HSA-9675108
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
ABC-family proteins mediated transport R-HSA-382556
Downstream TCR signaling R-HSA-202424
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RAS by GAPs R-HSA-5658442
Regulation of mitotic cell cycle R-HSA-453276
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular responses to stimuli R-HSA-8953897
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle R-HSA-1640170
Innate Immune System R-HSA-168249
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent DNA Damage Response R-HSA-69610
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
Neddylation R-HSA-8951664
Post-translational protein modification R-HSA-597592
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of AXIN R-HSA-4641257
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of Apoptosis R-HSA-169911
Degradation of DVL R-HSA-4641258
MAPK1/MAPK3 signaling R-HSA-5684996
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
ER-Phagosome pathway R-HSA-1236974
Metabolism R-HSA-1430728
Synthesis of DNA R-HSA-69239
Cellular response to chemical stress R-HSA-9711123
Degradation of GLI1 by the proteasome R-HSA-5610780
RNA Polymerase II Transcription R-HSA-73857
Signaling by ROBO receptors R-HSA-376176
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by WNT R-HSA-195721
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by Hedgehog R-HSA-5358351
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular responses to stress R-HSA-2262752
Hedgehog 'on' state R-HSA-5632684
G1/S DNA Damage Checkpoints R-HSA-69615
Hedgehog 'off' state R-HSA-5610787
S Phase R-HSA-69242
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Programmed Cell Death R-HSA-5357801
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
M Phase R-HSA-68886
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
UCH proteinases R-HSA-5689603
PIP3 activates AKT signaling R-HSA-1257604
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Generic Transcription Pathway R-HSA-212436
Cell Cycle, Mitotic R-HSA-69278
Separation of Sister Chromatids R-HSA-2467813
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of polyamines R-HSA-351202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic Anaphase R-HSA-68882
Deubiquitination R-HSA-5688426
Mitotic G2-G2/M phases R-HSA-453274
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
G2/M Transition R-HSA-69275
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Stabilization of p53 R-HSA-69541
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
PTEN Regulation R-HSA-6807070
MAPK6/MAPK4 signaling R-HSA-5687128
TCR signaling R-HSA-202403
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Orc1 removal from chromatin R-HSA-68949
HIV Infection R-HSA-162906
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Infectious disease R-HSA-5663205
Hh mutants are degraded by ERAD R-HSA-5362768
Cytokine Signaling in Immune system R-HSA-1280215
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
Metabolism of RNA R-HSA-8953854
Transport of small molecules R-HSA-382551
Metabolism of amino acids and derivatives R-HSA-71291
Vpu mediated degradation of CD4 R-HSA-180534
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Regulation of RUNX2 expression and activity R-HSA-8939902
Ub-specific processing proteases R-HSA-5689880
Vif-mediated degradation of APOBEC3G R-HSA-180585
G2/M Checkpoints R-HSA-69481
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication R-HSA-69306
Asymmetric localization of PCP proteins R-HSA-4608870
Intracellular signaling by second messengers R-HSA-9006925
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TCR signaling R-HSA-202403
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of RAS by GAPs R-HSA-5658442
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 family signaling R-HSA-446652
Hedgehog 'on' state R-HSA-5632684
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of PTEN stability and activity R-HSA-8948751
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G1/S DNA Damage Checkpoints R-HSA-69615
ABC transporter disorders R-HSA-5619084
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by Interleukins R-HSA-449147
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK family signaling cascades R-HSA-5683057
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by WNT R-HSA-195721
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle Checkpoints R-HSA-69620
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Orc1 removal from chromatin R-HSA-68949
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of Apoptosis R-HSA-169911
Neddylation R-HSA-8951664
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FCERI mediated NF-kB activation R-HSA-2871837
Transport of small molecules R-HSA-382551
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by Hedgehog R-HSA-5358351
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 signaling R-HSA-9020702
Cellular response to chemical stress R-HSA-9711123
Degradation of DVL R-HSA-4641258
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
UCH proteinases R-HSA-5689603
Immune System R-HSA-168256
p53-Independent DNA Damage Response R-HSA-69610
G2/M Transition R-HSA-69275
Hedgehog 'off' state R-HSA-5610787
Degradation of AXIN R-HSA-4641257
MAPK6/MAPK4 signaling R-HSA-5687128
Nervous system development R-HSA-9675108
Gene expression (Transcription) R-HSA-74160
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle R-HSA-1640170
HIV Infection R-HSA-162906
Infectious disease R-HSA-5663205
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Checkpoints R-HSA-69481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ER-Phagosome pathway R-HSA-1236974
PCP/CE pathway R-HSA-4086400
Vif-mediated degradation of APOBEC3G R-HSA-180585
Programmed Cell Death R-HSA-5357801
Synthesis of DNA R-HSA-69239
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism R-HSA-1430728
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular responses to stimuli R-HSA-8953897
M Phase R-HSA-68886
Axon guidance R-HSA-422475
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Developmental Biology R-HSA-1266738
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
Ub-specific processing proteases R-HSA-5689880
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hh mutants abrogate ligand secretion R-HSA-5387390
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
PTEN Regulation R-HSA-6807070
Metabolism of RNA R-HSA-8953854
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
Vpu mediated degradation of CD4 R-HSA-180534
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to hypoxia R-HSA-1234174
S Phase R-HSA-69242
Signal Transduction R-HSA-162582
Mitotic Metaphase and Anaphase R-HSA-2555396
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Post-translational protein modification R-HSA-597592
DNA Replication R-HSA-69306
Switching of origins to a post-replicative state R-HSA-69052
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Adaptive Immune System R-HSA-1280218
Metabolism of proteins R-HSA-392499
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of beta-catenin by the destruction complex R-HSA-195253
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Downstream TCR signaling R-HSA-202424
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Innate Immune System R-HSA-168249
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
Beta-catenin independent WNT signaling R-HSA-3858494
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Metaphase and Anaphase R-HSA-2555396
ER-Phagosome pathway R-HSA-1236974
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Post-translational protein modification R-HSA-597592
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
RNA Polymerase II Transcription R-HSA-73857
G2/M Transition R-HSA-69275
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by Interleukins R-HSA-449147
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PIP3 activates AKT signaling R-HSA-1257604
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
UCH proteinases R-HSA-5689603
Nervous system development R-HSA-9675108
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Generic Transcription Pathway R-HSA-212436
Switching of origins to a post-replicative state R-HSA-69052
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of RAS by GAPs R-HSA-5658442
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by WNT R-HSA-195721
Degradation of GLI1 by the proteasome R-HSA-5610780
Separation of Sister Chromatids R-HSA-2467813
HIV Infection R-HSA-162906
Antigen processing-Cross presentation R-HSA-1236975
FCERI mediated NF-kB activation R-HSA-2871837
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
p53-Dependent G1 DNA Damage Response R-HSA-69563
TCF dependent signaling in response to WNT R-HSA-201681
PTEN Regulation R-HSA-6807070
Synthesis of DNA R-HSA-69239
Axon guidance R-HSA-422475
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular response to chemical stress R-HSA-9711123
RAF/MAP kinase cascade R-HSA-5673001
PCP/CE pathway R-HSA-4086400
Metabolism of amino acids and derivatives R-HSA-71291
M Phase R-HSA-68886
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to hypoxia R-HSA-1234174
Neddylation R-HSA-8951664
Mitotic Anaphase R-HSA-68882
Cell Cycle Checkpoints R-HSA-69620
Infectious disease R-HSA-5663205
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Orc1 removal from chromatin R-HSA-68949
Class I MHC mediated antigen processing & presentation R-HSA-983169
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hedgehog 'off' state R-HSA-5610787
Hedgehog 'on' state R-HSA-5632684
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of beta-catenin by the destruction complex R-HSA-195253
MAPK family signaling cascades R-HSA-5683057
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Intracellular signaling by second messengers R-HSA-9006925
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Gene expression (Transcription) R-HSA-74160
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of proteins R-HSA-392499
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of AXIN R-HSA-4641257
Beta-catenin independent WNT signaling R-HSA-3858494
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of RNA R-HSA-8953854
Vif-mediated degradation of APOBEC3G R-HSA-180585
DNA Replication R-HSA-69306
Adaptive Immune System R-HSA-1280218
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cell Cycle, Mitotic R-HSA-69278
Metabolism of polyamines R-HSA-351202
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 signaling R-HSA-9020702
Interleukin-1 family signaling R-HSA-446652
ABC-family proteins mediated transport R-HSA-382556
Signaling by Hedgehog R-HSA-5358351
Transport of small molecules R-HSA-382551
Signal Transduction R-HSA-162582
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disease R-HSA-1643685
Disorders of transmembrane transporters R-HSA-5619115
ABC transporter disorders R-HSA-5619084
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
Hh mutants are degraded by ERAD R-HSA-5362768
Programmed Cell Death R-HSA-5357801
Vpu mediated degradation of CD4 R-HSA-180534
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX2 R-HSA-8878166
Deubiquitination R-HSA-5688426
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream TCR signaling R-HSA-202424
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle R-HSA-1640170
G2/M Checkpoints R-HSA-69481

Expression Atlas ENSG00000154611
NCBI gene (formerly Entrezgene) 143471
GeneCards 22985
HGNC Symbol HGNC:22985
MIM gene 617841
UniProtKB Gene Name Q8TAA3
WikiGene 143471