Gene: FLT3
Ensembl ID : ENSG00000122025
Description: fms related receptor tyrosine kinase 3
Gene Synonyms: CD135,FLK2,STK1
41 APIs:
134 Possible Orthologues:

tamatinib-resistant FLT3 mutants R-HSA-9703009
Immune System R-HSA-168256
STAT5 Activation R-HSA-9645135
Insulin receptor signalling cascade R-HSA-74751
gilteritinib-resistant FLT3 mutants R-HSA-9702590
IRS-related events triggered by IGF1R R-HSA-2428928
IRS-mediated signalling R-HSA-112399
FLT3 Signaling R-HSA-9607240
quizartinib-resistant FLT3 mutants R-HSA-9702620
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Insulin receptor R-HSA-74752
ponatinib-resistant FLT3 mutants R-HSA-9702614
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
crenolanib-resistant FLT3 mutants R-HSA-9702581
Negative regulation of the PI3K/AKT network R-HSA-199418
FLT3 signaling by CBL mutants R-HSA-9706377
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
sorafenib-resistant FLT3 mutants R-HSA-9702624
Drug resistance of FLT3 mutants R-HSA-9702506
linifanib-resistant FLT3 mutants R-HSA-9702998
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
tamatinib-resistant FLT3 mutants R-HSA-9703009
PI3K/AKT Signaling in Cancer R-HSA-2219528
semaxanib-resistant FLT3 mutants R-HSA-9702577
sunitinib-resistant FLT3 mutants R-HSA-9702632
Disease R-HSA-1643685
FLT3 mutants bind TKIs R-HSA-9702509
FLT3 signaling through SRC family kinases R-HSA-9706374
FLT3 signaling in disease R-HSA-9682385
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IGF1R signaling cascade R-HSA-2428924
pexidartinib-resistant FLT3 mutants R-HSA-9702605
Signal Transduction R-HSA-162582
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
KW2449-resistant FLT3 mutants R-HSA-9702569
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
tandutinib-resistant FLT3 mutants R-HSA-9702636
Cytokine Signaling in Immune system R-HSA-1280215
MAPK family signaling cascades R-HSA-5683057
Negative regulation of FLT3 R-HSA-9706369
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
midostaurin-resistant FLT3 mutants R-HSA-9702600
PI3K Cascade R-HSA-109704
MAPK1/MAPK3 signaling R-HSA-5684996
Insulin receptor signalling cascade R-HSA-74751
linifanib-resistant FLT3 mutants R-HSA-9702998
PIP3 activates AKT signaling R-HSA-1257604
quizartinib-resistant FLT3 mutants R-HSA-9702620
tamatinib-resistant FLT3 mutants R-HSA-9703009
tandutinib-resistant FLT3 mutants R-HSA-9702636
PI3K/AKT Signaling in Cancer R-HSA-2219528
Immune System R-HSA-168256
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Signal Transduction R-HSA-162582
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS-related events triggered by IGF1R R-HSA-2428928
KW2449-resistant FLT3 mutants R-HSA-9702569
MAPK family signaling cascades R-HSA-5683057
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FLT3 mutants bind TKIs R-HSA-9702509
PI3K Cascade R-HSA-109704
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Insulin receptor R-HSA-74752
IRS-mediated signalling R-HSA-112399
gilteritinib-resistant FLT3 mutants R-HSA-9702590
IGF1R signaling cascade R-HSA-2428924
sunitinib-resistant FLT3 mutants R-HSA-9702632
Negative regulation of FLT3 R-HSA-9706369
FLT3 Signaling R-HSA-9607240
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Drug resistance of FLT3 mutants R-HSA-9702506
FLT3 signaling by CBL mutants R-HSA-9706377
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
FLT3 signaling in disease R-HSA-9682385
sorafenib-resistant FLT3 mutants R-HSA-9702624
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
pexidartinib-resistant FLT3 mutants R-HSA-9702605
crenolanib-resistant FLT3 mutants R-HSA-9702581
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Intracellular signaling by second messengers R-HSA-9006925
FLT3 signaling through SRC family kinases R-HSA-9706374
STAT5 Activation R-HSA-9645135
MAPK1/MAPK3 signaling R-HSA-5684996
midostaurin-resistant FLT3 mutants R-HSA-9702600
semaxanib-resistant FLT3 mutants R-HSA-9702577
ponatinib-resistant FLT3 mutants R-HSA-9702614
FLT3 signaling by CBL mutants R-HSA-9706377
Cytokine Signaling in Immune system R-HSA-1280215
IRS-mediated signalling R-HSA-112399
FLT3 signaling in disease R-HSA-9682385
gilteritinib-resistant FLT3 mutants R-HSA-9702590
FLT3 signaling through SRC family kinases R-HSA-9706374
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
midostaurin-resistant FLT3 mutants R-HSA-9702600
IRS-related events triggered by IGF1R R-HSA-2428928
ponatinib-resistant FLT3 mutants R-HSA-9702614
Insulin receptor signalling cascade R-HSA-74751
FLT3 mutants bind TKIs R-HSA-9702509
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
crenolanib-resistant FLT3 mutants R-HSA-9702581
IGF1R signaling cascade R-HSA-2428924
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
sorafenib-resistant FLT3 mutants R-HSA-9702624
Negative regulation of the PI3K/AKT network R-HSA-199418
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Insulin receptor R-HSA-74752
Immune System R-HSA-168256
linifanib-resistant FLT3 mutants R-HSA-9702998
FLT3 Signaling R-HSA-9607240
sunitinib-resistant FLT3 mutants R-HSA-9702632
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
PI3K Cascade R-HSA-109704
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
MAPK family signaling cascades R-HSA-5683057
pexidartinib-resistant FLT3 mutants R-HSA-9702605
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Disease R-HSA-1643685
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
STAT5 Activation R-HSA-9645135
KW2449-resistant FLT3 mutants R-HSA-9702569
Negative regulation of FLT3 R-HSA-9706369
Drug resistance of FLT3 mutants R-HSA-9702506
PIP3 activates AKT signaling R-HSA-1257604
quizartinib-resistant FLT3 mutants R-HSA-9702620
tandutinib-resistant FLT3 mutants R-HSA-9702636
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
tamatinib-resistant FLT3 mutants R-HSA-9703009
semaxanib-resistant FLT3 mutants R-HSA-9702577
crenolanib-resistant FLT3 mutants R-HSA-9702581
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
RAF/MAP kinase cascade R-HSA-5673001
FLT3 Signaling R-HSA-9607240
linifanib-resistant FLT3 mutants R-HSA-9702998
Negative regulation of FLT3 R-HSA-9706369
gilteritinib-resistant FLT3 mutants R-HSA-9702590
MAPK1/MAPK3 signaling R-HSA-5684996
KW2449-resistant FLT3 mutants R-HSA-9702569
ponatinib-resistant FLT3 mutants R-HSA-9702614
FLT3 mutants bind TKIs R-HSA-9702509
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Drug resistance of FLT3 mutants R-HSA-9702506
FLT3 signaling through SRC family kinases R-HSA-9706374
midostaurin-resistant FLT3 mutants R-HSA-9702600
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
quizartinib-resistant FLT3 mutants R-HSA-9702620
Intracellular signaling by second messengers R-HSA-9006925
semaxanib-resistant FLT3 mutants R-HSA-9702577
PIP3 activates AKT signaling R-HSA-1257604
sorafenib-resistant FLT3 mutants R-HSA-9702624
FLT3 signaling in disease R-HSA-9682385
STAT5 Activation R-HSA-9645135
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
tandutinib-resistant FLT3 mutants R-HSA-9702636
sunitinib-resistant FLT3 mutants R-HSA-9702632
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IRS-mediated signalling R-HSA-112399
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Insulin receptor R-HSA-74752
IGF1R signaling cascade R-HSA-2428924
PI3K Cascade R-HSA-109704
MAPK family signaling cascades R-HSA-5683057
Insulin receptor signalling cascade R-HSA-74751
tamatinib-resistant FLT3 mutants R-HSA-9703009
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
PI3K/AKT Signaling in Cancer R-HSA-2219528
FLT3 signaling by CBL mutants R-HSA-9706377
pexidartinib-resistant FLT3 mutants R-HSA-9702605
Disease R-HSA-1643685
Negative regulation of the PI3K/AKT network R-HSA-199418
quizartinib-resistant FLT3 mutants R-HSA-9702620
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K/AKT Signaling in Cancer R-HSA-2219528
IRS-mediated signalling R-HSA-112399
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS-related events triggered by IGF1R R-HSA-2428928
sorafenib-resistant FLT3 mutants R-HSA-9702624
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
FLT3 Signaling R-HSA-9607240
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
crenolanib-resistant FLT3 mutants R-HSA-9702581
Insulin receptor signalling cascade R-HSA-74751
Negative regulation of the PI3K/AKT network R-HSA-199418
pexidartinib-resistant FLT3 mutants R-HSA-9702605
tamatinib-resistant FLT3 mutants R-HSA-9703009
Negative regulation of FLT3 R-HSA-9706369
MAPK1/MAPK3 signaling R-HSA-5684996
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
FLT3 signaling in disease R-HSA-9682385
gilteritinib-resistant FLT3 mutants R-HSA-9702590
PI3K Cascade R-HSA-109704
Disease R-HSA-1643685
KW2449-resistant FLT3 mutants R-HSA-9702569
MAPK family signaling cascades R-HSA-5683057
ponatinib-resistant FLT3 mutants R-HSA-9702614
Immune System R-HSA-168256
midostaurin-resistant FLT3 mutants R-HSA-9702600
semaxanib-resistant FLT3 mutants R-HSA-9702577
STAT5 Activation R-HSA-9645135
PIP3 activates AKT signaling R-HSA-1257604
Drug resistance of FLT3 mutants R-HSA-9702506
Signaling by Insulin receptor R-HSA-74752
IGF1R signaling cascade R-HSA-2428924
linifanib-resistant FLT3 mutants R-HSA-9702998
FLT3 signaling by CBL mutants R-HSA-9706377
tandutinib-resistant FLT3 mutants R-HSA-9702636
sunitinib-resistant FLT3 mutants R-HSA-9702632
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FLT3 mutants bind TKIs R-HSA-9702509
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Intracellular signaling by second messengers R-HSA-9006925
FLT3 signaling through SRC family kinases R-HSA-9706374
Drug resistance of FLT3 mutants R-HSA-9702506
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
IRS-related events triggered by IGF1R R-HSA-2428928
FLT3 signaling by CBL mutants R-HSA-9706377
pexidartinib-resistant FLT3 mutants R-HSA-9702605
sorafenib-resistant FLT3 mutants R-HSA-9702624
gilteritinib-resistant FLT3 mutants R-HSA-9702590
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
linifanib-resistant FLT3 mutants R-HSA-9702998
FLT3 signaling through SRC family kinases R-HSA-9706374
quizartinib-resistant FLT3 mutants R-HSA-9702620
RAF/MAP kinase cascade R-HSA-5673001
Intracellular signaling by second messengers R-HSA-9006925
sunitinib-resistant FLT3 mutants R-HSA-9702632
MAPK family signaling cascades R-HSA-5683057
IGF1R signaling cascade R-HSA-2428924
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of FLT3 R-HSA-9706369
Signal Transduction R-HSA-162582
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
crenolanib-resistant FLT3 mutants R-HSA-9702581
PI3K/AKT Signaling in Cancer R-HSA-2219528
Insulin receptor signalling cascade R-HSA-74751
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
FLT3 mutants bind TKIs R-HSA-9702509
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Insulin receptor R-HSA-74752
semaxanib-resistant FLT3 mutants R-HSA-9702577
tandutinib-resistant FLT3 mutants R-HSA-9702636
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
tamatinib-resistant FLT3 mutants R-HSA-9703009
FLT3 signaling in disease R-HSA-9682385
KW2449-resistant FLT3 mutants R-HSA-9702569
midostaurin-resistant FLT3 mutants R-HSA-9702600
ponatinib-resistant FLT3 mutants R-HSA-9702614
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
STAT5 Activation R-HSA-9645135
FLT3 Signaling R-HSA-9607240
IRS-mediated signalling R-HSA-112399
PI3K Cascade R-HSA-109704
crenolanib-resistant FLT3 mutants R-HSA-9702581
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
STAT5 Activation R-HSA-9645135
tandutinib-resistant FLT3 mutants R-HSA-9702636
Signaling by Insulin receptor R-HSA-74752
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
IGF1R signaling cascade R-HSA-2428924
Drug resistance of FLT3 mutants R-HSA-9702506
RAF/MAP kinase cascade R-HSA-5673001
PI3K/AKT Signaling in Cancer R-HSA-2219528
IRS-related events triggered by IGF1R R-HSA-2428928
Intracellular signaling by second messengers R-HSA-9006925
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Insulin receptor signalling cascade R-HSA-74751
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FLT3 signaling through SRC family kinases R-HSA-9706374
sorafenib-resistant FLT3 mutants R-HSA-9702624
gilteritinib-resistant FLT3 mutants R-HSA-9702590
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
IRS-mediated signalling R-HSA-112399
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K Cascade R-HSA-109704
FLT3 signaling by CBL mutants R-HSA-9706377
Negative regulation of the PI3K/AKT network R-HSA-199418
KW2449-resistant FLT3 mutants R-HSA-9702569
linifanib-resistant FLT3 mutants R-HSA-9702998
semaxanib-resistant FLT3 mutants R-HSA-9702577
FLT3 signaling in disease R-HSA-9682385
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
pexidartinib-resistant FLT3 mutants R-HSA-9702605
tamatinib-resistant FLT3 mutants R-HSA-9703009
sunitinib-resistant FLT3 mutants R-HSA-9702632
FLT3 Signaling R-HSA-9607240
FLT3 mutants bind TKIs R-HSA-9702509
Disease R-HSA-1643685
Negative regulation of FLT3 R-HSA-9706369
quizartinib-resistant FLT3 mutants R-HSA-9702620
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
ponatinib-resistant FLT3 mutants R-HSA-9702614
PIP3 activates AKT signaling R-HSA-1257604
midostaurin-resistant FLT3 mutants R-HSA-9702600
Immune System R-HSA-168256
crenolanib-resistant FLT3 mutants R-HSA-9702581
FLT3 signaling through SRC family kinases R-HSA-9706374
Signaling by Insulin receptor R-HSA-74752
tandutinib-resistant FLT3 mutants R-HSA-9702636
IRS-related events triggered by IGF1R R-HSA-2428928
quizartinib-resistant FLT3 mutants R-HSA-9702620
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
FLT3 signaling in disease R-HSA-9682385
PI3K Cascade R-HSA-109704
IRS-mediated signalling R-HSA-112399
sunitinib-resistant FLT3 mutants R-HSA-9702632
Intracellular signaling by second messengers R-HSA-9006925
FLT3 mutants bind TKIs R-HSA-9702509
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
gilteritinib-resistant FLT3 mutants R-HSA-9702590
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
FLT3 Signaling R-HSA-9607240
KW2449-resistant FLT3 mutants R-HSA-9702569
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
linifanib-resistant FLT3 mutants R-HSA-9702998
Drug resistance of FLT3 mutants R-HSA-9702506
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Immune System R-HSA-168256
sorafenib-resistant FLT3 mutants R-HSA-9702624
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
semaxanib-resistant FLT3 mutants R-HSA-9702577
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
midostaurin-resistant FLT3 mutants R-HSA-9702600
MAPK1/MAPK3 signaling R-HSA-5684996
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
pexidartinib-resistant FLT3 mutants R-HSA-9702605
ponatinib-resistant FLT3 mutants R-HSA-9702614
FLT3 signaling by CBL mutants R-HSA-9706377
STAT5 Activation R-HSA-9645135
Negative regulation of FLT3 R-HSA-9706369
Disease R-HSA-1643685
Insulin receptor signalling cascade R-HSA-74751
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
IGF1R signaling cascade R-HSA-2428924
Drug resistance of FLT3 mutants R-HSA-9702506
FLT3 signaling by CBL mutants R-HSA-9706377
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
FLT3 Signaling R-HSA-9607240
FLT3 mutants bind TKIs R-HSA-9702509
Negative regulation of the PI3K/AKT network R-HSA-199418
tandutinib-resistant FLT3 mutants R-HSA-9702636
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
gilteritinib-resistant FLT3 mutants R-HSA-9702590
tamatinib-resistant FLT3 mutants R-HSA-9703009
crenolanib-resistant FLT3 mutants R-HSA-9702581
Immune System R-HSA-168256
FLT3 signaling in disease R-HSA-9682385
linifanib-resistant FLT3 mutants R-HSA-9702998
Disease R-HSA-1643685
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PIP3 activates AKT signaling R-HSA-1257604
FLT3 signaling through SRC family kinases R-HSA-9706374
Negative regulation of FLT3 R-HSA-9706369
midostaurin-resistant FLT3 mutants R-HSA-9702600
PI3K Cascade R-HSA-109704
sunitinib-resistant FLT3 mutants R-HSA-9702632
STAT5 Activation R-HSA-9645135
RAF/MAP kinase cascade R-HSA-5673001
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Signaling by Insulin receptor R-HSA-74752
MAPK1/MAPK3 signaling R-HSA-5684996
quizartinib-resistant FLT3 mutants R-HSA-9702620
ponatinib-resistant FLT3 mutants R-HSA-9702614
IRS-related events triggered by IGF1R R-HSA-2428928
Signal Transduction R-HSA-162582
sorafenib-resistant FLT3 mutants R-HSA-9702624
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
pexidartinib-resistant FLT3 mutants R-HSA-9702605
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
semaxanib-resistant FLT3 mutants R-HSA-9702577
IGF1R signaling cascade R-HSA-2428924
MAPK family signaling cascades R-HSA-5683057
KW2449-resistant FLT3 mutants R-HSA-9702569
IRS-mediated signalling R-HSA-112399
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
Insulin receptor signalling cascade R-HSA-74751
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Insulin receptor R-HSA-74752
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
midostaurin-resistant FLT3 mutants R-HSA-9702600
FLT3 signaling through SRC family kinases R-HSA-9706374
FLT3 Signaling R-HSA-9607240
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
PI3K/AKT Signaling in Cancer R-HSA-2219528
Negative regulation of FLT3 R-HSA-9706369
Drug resistance of FLT3 mutants R-HSA-9702506
sorafenib-resistant FLT3 mutants R-HSA-9702624
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IRS-related events triggered by IGF1R R-HSA-2428928
FLT3 mutants bind TKIs R-HSA-9702509
IRS-mediated signalling R-HSA-112399
pexidartinib-resistant FLT3 mutants R-HSA-9702605
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
quizartinib-resistant FLT3 mutants R-HSA-9702620
semaxanib-resistant FLT3 mutants R-HSA-9702577
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
gilteritinib-resistant FLT3 mutants R-HSA-9702590
MAPK family signaling cascades R-HSA-5683057
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
FLT3 signaling by CBL mutants R-HSA-9706377
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
sunitinib-resistant FLT3 mutants R-HSA-9702632
STAT5 Activation R-HSA-9645135
tamatinib-resistant FLT3 mutants R-HSA-9703009
IGF1R signaling cascade R-HSA-2428924
Insulin receptor signalling cascade R-HSA-74751
ponatinib-resistant FLT3 mutants R-HSA-9702614
Signal Transduction R-HSA-162582
PI3K Cascade R-HSA-109704
linifanib-resistant FLT3 mutants R-HSA-9702998
tandutinib-resistant FLT3 mutants R-HSA-9702636
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PIP3 activates AKT signaling R-HSA-1257604
KW2449-resistant FLT3 mutants R-HSA-9702569
FLT3 signaling in disease R-HSA-9682385
crenolanib-resistant FLT3 mutants R-HSA-9702581
Disease R-HSA-1643685
lestaurtinib-resistant FLT3 mutants R-HSA-9702596

Expression Atlas ENSG00000122025
LRG display in Ensembl gene LRG_457
NCBI gene (formerly Entrezgene) 2322
GeneCards 3765
HGNC Symbol HGNC:3765
MIM gene 136351
MIM morbid 613065
UniProtKB Gene Name P36888
WikiGene 2322
Gene: JAK1
Ensembl ID : ENSG00000162434
Description: Janus kinase 1
Gene Synonyms: JAK1A,JAK1B,JTK3
19 APIs:
238 Possible Orthologues:

Disease R-HSA-1643685
Interferon gamma signaling R-HSA-877300
ISG15 antiviral mechanism R-HSA-1169408
Interleukin-21 signaling R-HSA-9020958
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-2 signaling R-HSA-9020558
Interleukin-9 signaling R-HSA-8985947
SARS-CoV Infections R-HSA-9679506
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Regulation of IFNA/IFNB signaling R-HSA-912694
Other interleukin signaling R-HSA-449836
Immune System R-HSA-168256
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-2 family signaling R-HSA-451927
Interleukin-12 signaling R-HSA-9020591
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-35 Signalling R-HSA-8984722
MAPK3 (ERK1) activation R-HSA-110056
Signal Transduction R-HSA-162582
Interleukin-27 signaling R-HSA-9020956
Interleukin-7 signaling R-HSA-1266695
Interleukin-10 signaling R-HSA-6783783
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
MAPK family signaling cascades R-HSA-5683057
Infectious disease R-HSA-5663205
Interleukin-6 signaling R-HSA-1059683
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-15 signaling R-HSA-8983432
Regulation of IFNG signaling R-HSA-877312
Interleukin receptor SHC signaling R-HSA-912526
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV-2 Infection R-HSA-9694516
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
SARS-CoV-2-host interactions R-HSA-9705683
Interferon Signaling R-HSA-913531
Interferon alpha/beta signaling R-HSA-909733
Signaling by Interleukins R-HSA-449147
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Interleukin-12 family signaling R-HSA-447115
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Interleukin-6 family signaling R-HSA-6783589
MAPK1 (ERK2) activation R-HSA-112411
Interleukin-20 family signaling R-HSA-8854691
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-12 signaling R-HSA-9020591
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Regulation of IFNG signaling R-HSA-877312
Interferon gamma signaling R-HSA-877300
Disease R-HSA-1643685
Interleukin-7 signaling R-HSA-1266695
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
MAPK1 (ERK2) activation R-HSA-112411
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Other interleukin signaling R-HSA-449836
Immune System R-HSA-168256
ISG15 antiviral mechanism R-HSA-1169408
MAPK family signaling cascades R-HSA-5683057
SARS-CoV-2 Infection R-HSA-9694516
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-2 family signaling R-HSA-451927
Interleukin-6 signaling R-HSA-1059683
RAF-independent MAPK1/3 activation R-HSA-112409
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by Interleukins R-HSA-449147
Interleukin-21 signaling R-HSA-9020958
Interleukin-12 family signaling R-HSA-447115
Interferon Signaling R-HSA-913531
Interleukin-35 Signalling R-HSA-8984722
Interleukin-6 family signaling R-HSA-6783589
Interleukin-27 signaling R-HSA-9020956
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
SARS-CoV Infections R-HSA-9679506
Interleukin-9 signaling R-HSA-8985947
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Interleukin-2 signaling R-HSA-9020558
MAPK3 (ERK1) activation R-HSA-110056
Regulation of IFNA/IFNB signaling R-HSA-912694
Interleukin receptor SHC signaling R-HSA-912526
Signal Transduction R-HSA-162582
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-15 signaling R-HSA-8983432
Interleukin-10 signaling R-HSA-6783783
Infectious disease R-HSA-5663205
Potential therapeutics for SARS R-HSA-9679191
Interleukin-20 family signaling R-HSA-8854691
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interferon alpha/beta signaling R-HSA-909733
Interferon gamma signaling R-HSA-877300
Interleukin-10 signaling R-HSA-6783783
MAPK1/MAPK3 signaling R-HSA-5684996
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Potential therapeutics for SARS R-HSA-9679191
MAPK3 (ERK1) activation R-HSA-110056
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Interferon Signaling R-HSA-913531
Interleukin-35 Signalling R-HSA-8984722
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Signal Transduction R-HSA-162582
Regulation of IFNA/IFNB signaling R-HSA-912694
ISG15 antiviral mechanism R-HSA-1169408
Infectious disease R-HSA-5663205
SARS-CoV-2 Infection R-HSA-9694516
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
SARS-CoV-2-host interactions R-HSA-9705683
Interleukin-15 signaling R-HSA-8983432
Interferon alpha/beta signaling R-HSA-909733
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-7 signaling R-HSA-1266695
Signaling by Interleukins R-HSA-449147
Interleukin-12 signaling R-HSA-9020591
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by CSF3 (G-CSF) R-HSA-9674555
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-6 family signaling R-HSA-6783589
Interleukin-9 signaling R-HSA-8985947
Immune System R-HSA-168256
Interleukin-21 signaling R-HSA-9020958
Disease R-HSA-1643685
Interleukin-6 signaling R-HSA-1059683
Regulation of IFNG signaling R-HSA-877312
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
SARS-CoV Infections R-HSA-9679506
MAPK family signaling cascades R-HSA-5683057
Interleukin-20 family signaling R-HSA-8854691
Interleukin-12 family signaling R-HSA-447115
Interleukin-2 signaling R-HSA-9020558
Interleukin receptor SHC signaling R-HSA-912526
Interleukin-27 signaling R-HSA-9020956
Interleukin-2 family signaling R-HSA-451927
MAPK1 (ERK2) activation R-HSA-112411
Other interleukin signaling R-HSA-449836
Interleukin-35 Signalling R-HSA-8984722
Signaling by CSF3 (G-CSF) R-HSA-9674555
Immune System R-HSA-168256
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
ISG15 antiviral mechanism R-HSA-1169408
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-20 family signaling R-HSA-8854691
MAPK1 (ERK2) activation R-HSA-112411
Interleukin-15 signaling R-HSA-8983432
Interleukin-6 family signaling R-HSA-6783589
Potential therapeutics for SARS R-HSA-9679191
Interleukin-21 signaling R-HSA-9020958
Regulation of IFNA/IFNB signaling R-HSA-912694
Infectious disease R-HSA-5663205
RAF-independent MAPK1/3 activation R-HSA-112409
SARS-CoV Infections R-HSA-9679506
Interleukin-27 signaling R-HSA-9020956
Interleukin-12 family signaling R-HSA-447115
Interleukin-6 signaling R-HSA-1059683
Signal Transduction R-HSA-162582
Interleukin-2 signaling R-HSA-9020558
Interferon alpha/beta signaling R-HSA-909733
Interleukin-10 signaling R-HSA-6783783
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Regulation of IFNG signaling R-HSA-877312
MAPK1/MAPK3 signaling R-HSA-5684996
Cytokine Signaling in Immune system R-HSA-1280215
SARS-CoV-2-host interactions R-HSA-9705683
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Disease R-HSA-1643685
SARS-CoV-2 Infection R-HSA-9694516
Interleukin-7 signaling R-HSA-1266695
MAPK family signaling cascades R-HSA-5683057
Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Interleukin-12 signaling R-HSA-9020591
Interleukin receptor SHC signaling R-HSA-912526
Other interleukin signaling R-HSA-449836
Interleukin-9 signaling R-HSA-8985947
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-2 family signaling R-HSA-451927
Interferon Signaling R-HSA-913531
Interferon gamma signaling R-HSA-877300
Interleukin-15 signaling R-HSA-8983432
Infectious disease R-HSA-5663205
Interleukin-7 signaling R-HSA-1266695
SARS-CoV-2 Infection R-HSA-9694516
Interleukin-6 signaling R-HSA-1059683
RAF/MAP kinase cascade R-HSA-5673001
Interferon gamma signaling R-HSA-877300
Interleukin-12 family signaling R-HSA-447115
Regulation of IFNG signaling R-HSA-877312
SARS-CoV-2-host interactions R-HSA-9705683
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Interferon Signaling R-HSA-913531
Interleukin-2 signaling R-HSA-9020558
Regulation of IFNA/IFNB signaling R-HSA-912694
Other interleukin signaling R-HSA-449836
Interleukin-21 signaling R-HSA-9020958
Signaling by Interleukins R-HSA-449147
Disease R-HSA-1643685
Interleukin-10 signaling R-HSA-6783783
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Interleukin-20 family signaling R-HSA-8854691
Interleukin-6 family signaling R-HSA-6783589
SARS-CoV Infections R-HSA-9679506
Immune System R-HSA-168256
Interleukin-9 signaling R-HSA-8985947
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin receptor SHC signaling R-HSA-912526
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-27 signaling R-HSA-9020956
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Interleukin-12 signaling R-HSA-9020591
MAPK3 (ERK1) activation R-HSA-110056
Potential therapeutics for SARS R-HSA-9679191
Interleukin-2 family signaling R-HSA-451927
Interleukin-35 Signalling R-HSA-8984722
Signal Transduction R-HSA-162582
MAPK1 (ERK2) activation R-HSA-112411
MAPK family signaling cascades R-HSA-5683057
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
ISG15 antiviral mechanism R-HSA-1169408
Interferon alpha/beta signaling R-HSA-909733
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interferon alpha/beta signaling R-HSA-909733
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Regulation of IFNG signaling R-HSA-877312
Immune System R-HSA-168256
Regulation of IFNA/IFNB signaling R-HSA-912694
Interferon gamma signaling R-HSA-877300
Disease R-HSA-1643685
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-2 family signaling R-HSA-451927
Signal Transduction R-HSA-162582
MAPK1 (ERK2) activation R-HSA-112411
Interferon Signaling R-HSA-913531
SARS-CoV-2 Infection R-HSA-9694516
ISG15 antiviral mechanism R-HSA-1169408
Interleukin-6 signaling R-HSA-1059683
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-10 signaling R-HSA-6783783
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Interleukin-15 signaling R-HSA-8983432
Interleukin-35 Signalling R-HSA-8984722
Interleukin-12 signaling R-HSA-9020591
MAPK family signaling cascades R-HSA-5683057
Interleukin-6 family signaling R-HSA-6783589
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-12 family signaling R-HSA-447115
SARS-CoV Infections R-HSA-9679506
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Interleukin-21 signaling R-HSA-9020958
Interleukin-9 signaling R-HSA-8985947
SARS-CoV-2-host interactions R-HSA-9705683
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-20 family signaling R-HSA-8854691
Interleukin receptor SHC signaling R-HSA-912526
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Potential therapeutics for SARS R-HSA-9679191
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Signaling by Interleukins R-HSA-449147
RAF/MAP kinase cascade R-HSA-5673001
Infectious disease R-HSA-5663205
Other interleukin signaling R-HSA-449836
Interleukin-27 signaling R-HSA-9020956
Interleukin-2 signaling R-HSA-9020558
Interleukin-7 signaling R-HSA-1266695
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Interleukin-20 family signaling R-HSA-8854691
Signaling by CSF3 (G-CSF) R-HSA-9674555
SARS-CoV-2 Infection R-HSA-9694516
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Interferon alpha/beta signaling R-HSA-909733
MAPK family signaling cascades R-HSA-5683057
Interleukin-2 family signaling R-HSA-451927
SARS-CoV-2-host interactions R-HSA-9705683
Signal Transduction R-HSA-162582
ISG15 antiviral mechanism R-HSA-1169408
Interleukin-7 signaling R-HSA-1266695
Interleukin-10 signaling R-HSA-6783783
Interleukin-21 signaling R-HSA-9020958
Interleukin receptor SHC signaling R-HSA-912526
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Regulation of IFNG signaling R-HSA-877312
Interleukin-15 signaling R-HSA-8983432
Other interleukin signaling R-HSA-449836
Signaling by Interleukins R-HSA-449147
Interleukin-2 signaling R-HSA-9020558
Interferon Signaling R-HSA-913531
MAPK3 (ERK1) activation R-HSA-110056
SARS-CoV Infections R-HSA-9679506
Interleukin-9 signaling R-HSA-8985947
Interleukin-12 signaling R-HSA-9020591
Interferon gamma signaling R-HSA-877300
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Interleukin-6 family signaling R-HSA-6783589
Infectious disease R-HSA-5663205
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Interleukin-35 Signalling R-HSA-8984722
Immune System R-HSA-168256
Regulation of IFNA/IFNB signaling R-HSA-912694
MAPK1 (ERK2) activation R-HSA-112411
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
RAF/MAP kinase cascade R-HSA-5673001
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-6 signaling R-HSA-1059683
Potential therapeutics for SARS R-HSA-9679191
Interleukin-12 family signaling R-HSA-447115
Interleukin-27 signaling R-HSA-9020956
Cytokine Signaling in Immune system R-HSA-1280215
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-21 signaling R-HSA-9020958
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Interleukin-2 family signaling R-HSA-451927
Interleukin-7 signaling R-HSA-1266695
Signaling by CSF3 (G-CSF) R-HSA-9674555
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Interleukin-35 Signalling R-HSA-8984722
MAPK1/MAPK3 signaling R-HSA-5684996
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Immune System R-HSA-168256
Interleukin-20 family signaling R-HSA-8854691
Regulation of IFNG signaling R-HSA-877312
SARS-CoV-2 Infection R-HSA-9694516
MAPK3 (ERK1) activation R-HSA-110056
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-9 signaling R-HSA-8985947
Other interleukin signaling R-HSA-449836
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Interleukin-6 family signaling R-HSA-6783589
MAPK family signaling cascades R-HSA-5683057
MAPK1 (ERK2) activation R-HSA-112411
Interleukin receptor SHC signaling R-HSA-912526
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
SARS-CoV Infections R-HSA-9679506
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
ISG15 antiviral mechanism R-HSA-1169408
Interleukin-12 family signaling R-HSA-447115
Disease R-HSA-1643685
Interferon gamma signaling R-HSA-877300
Infectious disease R-HSA-5663205
Interferon Signaling R-HSA-913531
Interleukin-12 signaling R-HSA-9020591
Potential therapeutics for SARS R-HSA-9679191
Interleukin-27 signaling R-HSA-9020956
Regulation of IFNA/IFNB signaling R-HSA-912694
Interferon alpha/beta signaling R-HSA-909733
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Interleukin-10 signaling R-HSA-6783783
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-6 signaling R-HSA-1059683
Interleukin-2 signaling R-HSA-9020558
SARS-CoV-2-host interactions R-HSA-9705683
Interleukin-15 signaling R-HSA-8983432
ISG15 antiviral mechanism R-HSA-1169408
Interleukin-7 signaling R-HSA-1266695
Immune System R-HSA-168256
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
SARS-CoV-2-host interactions R-HSA-9705683
Potential therapeutics for SARS R-HSA-9679191
Interleukin-27 signaling R-HSA-9020956
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Interleukin-20 family signaling R-HSA-8854691
Interleukin-15 signaling R-HSA-8983432
Interleukin-2 family signaling R-HSA-451927
Interleukin-10 signaling R-HSA-6783783
SARS-CoV Infections R-HSA-9679506
Interleukin-2 signaling R-HSA-9020558
Interleukin-35 Signalling R-HSA-8984722
Regulation of IFNG signaling R-HSA-877312
Signal Transduction R-HSA-162582
Interleukin-21 signaling R-HSA-9020958
Disease R-HSA-1643685
Interleukin-6 family signaling R-HSA-6783589
Interferon Signaling R-HSA-913531
RAF-independent MAPK1/3 activation R-HSA-112409
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
MAPK1 (ERK2) activation R-HSA-112411
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of IFNA/IFNB signaling R-HSA-912694
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
SARS-CoV-2 Infection R-HSA-9694516
Interleukin-6 signaling R-HSA-1059683
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
MAPK family signaling cascades R-HSA-5683057
Interferon alpha/beta signaling R-HSA-909733
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin receptor SHC signaling R-HSA-912526
Infectious disease R-HSA-5663205
Interleukin-12 signaling R-HSA-9020591
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-12 family signaling R-HSA-447115
Interleukin-9 signaling R-HSA-8985947
Signaling by Interleukins R-HSA-449147
Other interleukin signaling R-HSA-449836
Interferon gamma signaling R-HSA-877300
Infectious disease R-HSA-5663205
Interleukin-9 signaling R-HSA-8985947
Interferon Signaling R-HSA-913531
Disease R-HSA-1643685
Interleukin-6 signaling R-HSA-1059683
MAPK1 (ERK2) activation R-HSA-112411
RAF-independent MAPK1/3 activation R-HSA-112409
Other interleukin signaling R-HSA-449836
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
RAF/MAP kinase cascade R-HSA-5673001
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-12 family signaling R-HSA-447115
MAPK family signaling cascades R-HSA-5683057
Immune System R-HSA-168256
Interleukin receptor SHC signaling R-HSA-912526
SARS-CoV-2-host interactions R-HSA-9705683
Regulation of IFNG signaling R-HSA-877312
Interleukin-2 family signaling R-HSA-451927
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Regulation of IFNA/IFNB signaling R-HSA-912694
Interleukin-10 signaling R-HSA-6783783
MAPK1/MAPK3 signaling R-HSA-5684996
Interferon gamma signaling R-HSA-877300
Interleukin-20 family signaling R-HSA-8854691
Signaling by Interleukins R-HSA-449147
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Interleukin-27 signaling R-HSA-9020956
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Interferon alpha/beta signaling R-HSA-909733
Interleukin-15 signaling R-HSA-8983432
Interleukin-2 signaling R-HSA-9020558
Interleukin-21 signaling R-HSA-9020958
MAPK3 (ERK1) activation R-HSA-110056
Cytokine Signaling in Immune system R-HSA-1280215
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
ISG15 antiviral mechanism R-HSA-1169408
Interleukin-7 signaling R-HSA-1266695
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
SARS-CoV Infections R-HSA-9679506
Interleukin-35 Signalling R-HSA-8984722
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV-2 Infection R-HSA-9694516
Signal Transduction R-HSA-162582
Interleukin-6 family signaling R-HSA-6783589
Interleukin-12 signaling R-HSA-9020591

Expression Atlas ENSG00000162434
LRG display in Ensembl gene LRG_1398
NCBI gene (formerly Entrezgene) 3716
GeneCards 6190
HGNC Symbol HGNC:6190
MIM gene 147795
MIM morbid 618999
UniProtKB Gene Name P23458
WikiGene 3716
Gene: FRK
Ensembl ID : ENSG00000111816
Description: fyn related Src family tyrosine kinase
Gene Synonyms: GTK,PTK5,RAK
1 APIs:
217 Possible Orthologues:

Intracellular signaling by second messengers R-HSA-9006925
Immune System R-HSA-168256
PTEN Regulation R-HSA-6807070
Neutrophil degranulation R-HSA-6798695
PIP3 activates AKT signaling R-HSA-1257604
Regulation of PTEN stability and activity R-HSA-8948751
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
PTEN Regulation R-HSA-6807070
Neutrophil degranulation R-HSA-6798695
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Regulation of PTEN stability and activity R-HSA-8948751
Innate Immune System R-HSA-168249
Regulation of PTEN stability and activity R-HSA-8948751
Neutrophil degranulation R-HSA-6798695
PTEN Regulation R-HSA-6807070
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Innate Immune System R-HSA-168249
PIP3 activates AKT signaling R-HSA-1257604
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
Neutrophil degranulation R-HSA-6798695
PIP3 activates AKT signaling R-HSA-1257604
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
PTEN Regulation R-HSA-6807070
Intracellular signaling by second messengers R-HSA-9006925
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Neutrophil degranulation R-HSA-6798695
Regulation of PTEN stability and activity R-HSA-8948751
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
PIP3 activates AKT signaling R-HSA-1257604
Regulation of PTEN stability and activity R-HSA-8948751
PTEN Regulation R-HSA-6807070
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Regulation of PTEN stability and activity R-HSA-8948751
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
PTEN Regulation R-HSA-6807070
Regulation of PTEN stability and activity R-HSA-8948751
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Innate Immune System R-HSA-168249
PTEN Regulation R-HSA-6807070
Neutrophil degranulation R-HSA-6798695
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
PIP3 activates AKT signaling R-HSA-1257604

Expression Atlas ENSG00000111816
NCBI gene (formerly Entrezgene) 2444
GeneCards 3955
HGNC Symbol HGNC:3955
MIM gene 606573
UniProtKB Gene Name P42685
WikiGene 2444
Gene: FLT1
Ensembl ID : ENSG00000102755
Description: fms related receptor tyrosine kinase 1
Gene Synonyms: FLT,VEGFR1
45 APIs:
199 Possible Orthologues:

Signaling by VEGF R-HSA-194138
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signaling by VEGF R-HSA-194138
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signal Transduction R-HSA-162582
VEGF ligand-receptor interactions R-HSA-194313
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
VEGF ligand-receptor interactions R-HSA-194313
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF ligand-receptor interactions R-HSA-194313
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signal Transduction R-HSA-162582
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
VEGF ligand-receptor interactions R-HSA-194313
Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signal Transduction R-HSA-162582
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signaling by VEGF R-HSA-194138

Expression Atlas ENSG00000102755
LRG display in Ensembl gene LRG_425
NCBI gene (formerly Entrezgene) 2321
GeneCards 3763
HGNC Symbol HGNC:3763
MIM gene 165070
UniProtKB Gene Name P17948
WikiGene 2321
Gene: JAK2
Ensembl ID : ENSG00000096968
Description: Janus kinase 2
Gene Synonyms: JTK10
23 APIs:
265 Possible Orthologues:

G1 Phase R-HSA-69236
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-2 family signaling R-HSA-451927
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Interleukin-6 signaling R-HSA-1059683
Interleukin-6 family signaling R-HSA-6783589
Mitotic G1 phase and G1/S transition R-HSA-453279
Chromatin organization R-HSA-4839726
Erythropoietin activates RAS R-HSA-9027284
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Infectious disease R-HSA-5663205
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV Infections R-HSA-9679506
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-23 signaling R-HSA-9020933
Signaling by KIT in disease R-HSA-9669938
RAF activation R-HSA-5673000
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
G1 Phase R-HSA-69236
Interferon gamma signaling R-HSA-877300
Interleukin-12 signaling R-HSA-9020591
Interleukin-35 Signalling R-HSA-8984722
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Growth hormone receptor signaling R-HSA-982772
Cyclin D associated events in G1 R-HSA-69231
Interleukin-12 family signaling R-HSA-447115
MAPK family signaling cascades R-HSA-5683057
Signaling by Erythropoietin R-HSA-9006335
Prolactin receptor signaling R-HSA-1170546
Interleukin-27 signaling R-HSA-9020956
Disease R-HSA-1643685
Hemostasis R-HSA-109582
RMTs methylate histone arginines R-HSA-3214858
Potential therapeutics for SARS R-HSA-9679191
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Erythropoietin activates STAT5 R-HSA-9027283
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-20 family signaling R-HSA-8854691
Signaling by Leptin R-HSA-2586552
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK1 (ERK2) activation R-HSA-112411
Signaling by SCF-KIT R-HSA-1433557
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Oncogenic MAPK signaling R-HSA-6802957
Signaling by RAS mutants R-HSA-6802949
Immune System R-HSA-168256
Interferon Signaling R-HSA-913531
Signaling by Interleukins R-HSA-449147
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Chromatin modifying enzymes R-HSA-3247509
Regulation of IFNG signaling R-HSA-877312
Signaling by RAF1 mutants R-HSA-9656223
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Cell Cycle R-HSA-1640170
Interleukin receptor SHC signaling R-HSA-912526
Interleukin-2 family signaling R-HSA-451927
Signaling by Leptin R-HSA-2586552
Interleukin-6 family signaling R-HSA-6783589
Cell Cycle R-HSA-1640170
Signal Transduction R-HSA-162582
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Chromatin modifying enzymes R-HSA-3247509
Interleukin-12 family signaling R-HSA-447115
Growth hormone receptor signaling R-HSA-982772
Potential therapeutics for SARS R-HSA-9679191
Erythropoietin activates RAS R-HSA-9027284
Interferon Signaling R-HSA-913531
Interleukin-27 signaling R-HSA-9020956
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Interleukin-12 signaling R-HSA-9020591
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-23 signaling R-HSA-9020933
Interferon gamma signaling R-HSA-877300
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Regulation of IFNG signaling R-HSA-877312
Disease R-HSA-1643685
Interleukin-20 family signaling R-HSA-8854691
RAF-independent MAPK1/3 activation R-HSA-112409
Cyclin D associated events in G1 R-HSA-69231
Signaling by Erythropoietin R-HSA-9006335
Erythropoietin activates STAT5 R-HSA-9027283
MAPK family signaling cascades R-HSA-5683057
Signaling by RAF1 mutants R-HSA-9656223
Cytokine Signaling in Immune system R-HSA-1280215
Chromatin organization R-HSA-4839726
RMTs methylate histone arginines R-HSA-3214858
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
G1 Phase R-HSA-69236
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Interleukin-35 Signalling R-HSA-8984722
Factors involved in megakaryocyte development and platelet production R-HSA-983231
MAPK3 (ERK1) activation R-HSA-110056
Infectious disease R-HSA-5663205
MAPK1 (ERK2) activation R-HSA-112411
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Prolactin receptor signaling R-HSA-1170546
Mitotic G1 phase and G1/S transition R-HSA-453279
Oncogenic MAPK signaling R-HSA-6802957
Interleukin-6 signaling R-HSA-1059683
Signaling by RAS mutants R-HSA-6802949
Interleukin receptor SHC signaling R-HSA-912526
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
RAF activation R-HSA-5673000
Signaling downstream of RAS mutants R-HSA-9649948
Cell Cycle, Mitotic R-HSA-69278
Signaling by KIT in disease R-HSA-9669938
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hemostasis R-HSA-109582
Signaling by CSF3 (G-CSF) R-HSA-9674555
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
SARS-CoV Infections R-HSA-9679506
RAF/MAP kinase cascade R-HSA-5673001
Chromatin modifying enzymes R-HSA-3247509
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Cell Cycle R-HSA-1640170
Interleukin-12 family signaling R-HSA-447115
Interleukin-35 Signalling R-HSA-8984722
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Interleukin-6 signaling R-HSA-1059683
Immune System R-HSA-168256
Interleukin receptor SHC signaling R-HSA-912526
G1 Phase R-HSA-69236
Growth hormone receptor signaling R-HSA-982772
Interferon Signaling R-HSA-913531
Signaling by Erythropoietin R-HSA-9006335
RAF activation R-HSA-5673000
Erythropoietin activates STAT5 R-HSA-9027283
Erythropoietin activates RAS R-HSA-9027284
Interferon gamma signaling R-HSA-877300
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-20 family signaling R-HSA-8854691
Interleukin-6 family signaling R-HSA-6783589
Interleukin-27 signaling R-HSA-9020956
Infectious disease R-HSA-5663205
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of IFNG signaling R-HSA-877312
Potential therapeutics for SARS R-HSA-9679191
Prolactin receptor signaling R-HSA-1170546
MAPK3 (ERK1) activation R-HSA-110056
Signaling by SCF-KIT R-HSA-1433557
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Disease R-HSA-1643685
Interleukin-23 signaling R-HSA-9020933
Signal Transduction R-HSA-162582
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Signaling by RAS mutants R-HSA-6802949
Cell Cycle, Mitotic R-HSA-69278
Cytokine Signaling in Immune system R-HSA-1280215
SARS-CoV Infections R-HSA-9679506
MAPK family signaling cascades R-HSA-5683057
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Cyclin D associated events in G1 R-HSA-69231
RMTs methylate histone arginines R-HSA-3214858
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Interleukins R-HSA-449147
Signaling by KIT in disease R-HSA-9669938
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Oncogenic MAPK signaling R-HSA-6802957
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-12 signaling R-HSA-9020591
Signaling by Leptin R-HSA-2586552
Chromatin organization R-HSA-4839726
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-2 family signaling R-HSA-451927
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK1 (ERK2) activation R-HSA-112411
Hemostasis R-HSA-109582
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-23 signaling R-HSA-9020933
Signaling downstream of RAS mutants R-HSA-9649948
Potential therapeutics for SARS R-HSA-9679191
Interleukin-2 family signaling R-HSA-451927
Erythropoietin activates STAT5 R-HSA-9027283
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Prolactin receptor signaling R-HSA-1170546
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RMTs methylate histone arginines R-HSA-3214858
MAPK1 (ERK2) activation R-HSA-112411
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Interferon gamma signaling R-HSA-877300
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-20 family signaling R-HSA-8854691
Cell Cycle R-HSA-1640170
Hemostasis R-HSA-109582
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Interleukin-35 Signalling R-HSA-8984722
Cell Cycle, Mitotic R-HSA-69278
Signal Transduction R-HSA-162582
Chromatin modifying enzymes R-HSA-3247509
Disease R-HSA-1643685
Signaling by CSF3 (G-CSF) R-HSA-9674555
G1 Phase R-HSA-69236
Cyclin D associated events in G1 R-HSA-69231
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
Signaling by RAS mutants R-HSA-6802949
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Chromatin organization R-HSA-4839726
MAPK3 (ERK1) activation R-HSA-110056
Signaling by KIT in disease R-HSA-9669938
Interferon Signaling R-HSA-913531
Signaling by SCF-KIT R-HSA-1433557
MAPK family signaling cascades R-HSA-5683057
Interleukin-6 signaling R-HSA-1059683
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by BRAF and RAF1 fusions R-HSA-6802952
RAF-independent MAPK1/3 activation R-HSA-112409
Erythropoietin activates RAS R-HSA-9027284
Signaling by RAF1 mutants R-HSA-9656223
RAF activation R-HSA-5673000
Factors involved in megakaryocyte development and platelet production R-HSA-983231
SARS-CoV Infections R-HSA-9679506
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Regulation of IFNG signaling R-HSA-877312
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Oncogenic MAPK signaling R-HSA-6802957
Immune System R-HSA-168256
Signaling by Leptin R-HSA-2586552
Interleukin-12 family signaling R-HSA-447115
Interleukin-27 signaling R-HSA-9020956
Interleukin receptor SHC signaling R-HSA-912526
Mitotic G1 phase and G1/S transition R-HSA-453279
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-6 family signaling R-HSA-6783589
Signaling by Erythropoietin R-HSA-9006335
Interleukin-12 signaling R-HSA-9020591
Growth hormone receptor signaling R-HSA-982772
Interleukin-20 family signaling R-HSA-8854691
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Immune System R-HSA-168256
Regulation of IFNG signaling R-HSA-877312
Chromatin modifying enzymes R-HSA-3247509
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Chromatin organization R-HSA-4839726
Erythropoietin activates STAT5 R-HSA-9027283
Potential therapeutics for SARS R-HSA-9679191
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
SARS-CoV Infections R-HSA-9679506
Oncogenic MAPK signaling R-HSA-6802957
G1 Phase R-HSA-69236
Interleukin-12 family signaling R-HSA-447115
Cyclin D associated events in G1 R-HSA-69231
Interleukin-27 signaling R-HSA-9020956
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Erythropoietin activates RAS R-HSA-9027284
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Interleukin-6 signaling R-HSA-1059683
Signaling by Interleukins R-HSA-449147
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Hemostasis R-HSA-109582
Signaling by RAF1 mutants R-HSA-9656223
Cell Cycle R-HSA-1640170
Mitotic G1 phase and G1/S transition R-HSA-453279
Factors involved in megakaryocyte development and platelet production R-HSA-983231
RAF-independent MAPK1/3 activation R-HSA-112409
Growth hormone receptor signaling R-HSA-982772
Signaling by KIT in disease R-HSA-9669938
Cytokine Signaling in Immune system R-HSA-1280215
MAPK1 (ERK2) activation R-HSA-112411
RMTs methylate histone arginines R-HSA-3214858
Cell Cycle, Mitotic R-HSA-69278
Interferon gamma signaling R-HSA-877300
Signaling by Erythropoietin R-HSA-9006335
Prolactin receptor signaling R-HSA-1170546
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-35 Signalling R-HSA-8984722
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Interleukin receptor SHC signaling R-HSA-912526
Interferon Signaling R-HSA-913531
Signaling by RAS mutants R-HSA-6802949
Interleukin-2 family signaling R-HSA-451927
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-6 family signaling R-HSA-6783589
Disease R-HSA-1643685
MAPK family signaling cascades R-HSA-5683057
RAF activation R-HSA-5673000
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Signaling by BRAF and RAF1 fusions R-HSA-6802952
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling downstream of RAS mutants R-HSA-9649948
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Signaling by SCF-KIT R-HSA-1433557
Interleukin-12 signaling R-HSA-9020591
Signaling by Leptin R-HSA-2586552
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Infectious disease R-HSA-5663205
Interleukin-23 signaling R-HSA-9020933
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Leptin R-HSA-2586552
Hemostasis R-HSA-109582
Regulation of IFNG signaling R-HSA-877312
Growth hormone receptor signaling R-HSA-982772
RAF activation R-HSA-5673000
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Interferon Signaling R-HSA-913531
Prolactin receptor signaling R-HSA-1170546
Cell Cycle R-HSA-1640170
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by RAS mutants R-HSA-6802949
Signaling by KIT in disease R-HSA-9669938
Signaling by Interleukins R-HSA-449147
Cyclin D associated events in G1 R-HSA-69231
RMTs methylate histone arginines R-HSA-3214858
Interleukin-2 family signaling R-HSA-451927
SARS-CoV Infections R-HSA-9679506
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Erythropoietin R-HSA-9006335
Disease R-HSA-1643685
Erythropoietin activates STAT5 R-HSA-9027283
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Chromatin modifying enzymes R-HSA-3247509
Erythropoietin activates RAS R-HSA-9027284
Interleukin-12 family signaling R-HSA-447115
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-6 family signaling R-HSA-6783589
Infectious disease R-HSA-5663205
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Interleukin receptor SHC signaling R-HSA-912526
Signaling by BRAF and RAF1 fusions R-HSA-6802952
G1 Phase R-HSA-69236
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-23 signaling R-HSA-9020933
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
MAPK1 (ERK2) activation R-HSA-112411
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-12 signaling R-HSA-9020591
Interleukin-6 signaling R-HSA-1059683
Chromatin organization R-HSA-4839726
Immune System R-HSA-168256
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle, Mitotic R-HSA-69278
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Interleukin-27 signaling R-HSA-9020956
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Potential therapeutics for SARS R-HSA-9679191
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Signaling by CSF3 (G-CSF) R-HSA-9674555
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-20 family signaling R-HSA-8854691
Interleukin-35 Signalling R-HSA-8984722
Signaling by SCF-KIT R-HSA-1433557
Oncogenic MAPK signaling R-HSA-6802957
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
MAPK1/MAPK3 signaling R-HSA-5684996
Interferon gamma signaling R-HSA-877300
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signaling by RAF1 mutants R-HSA-9656223
Signal Transduction R-HSA-162582
Interleukin-6 family signaling R-HSA-6783589
Cell Cycle, Mitotic R-HSA-69278
Interleukin-6 signaling R-HSA-1059683
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin receptor SHC signaling R-HSA-912526
Interleukin-23 signaling R-HSA-9020933
Signaling by Leptin R-HSA-2586552
Cyclin D associated events in G1 R-HSA-69231
RAF-independent MAPK1/3 activation R-HSA-112409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-12 signaling R-HSA-9020591
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Cytokine Signaling in Immune system R-HSA-1280215
Chromatin modifying enzymes R-HSA-3247509
Oncogenic MAPK signaling R-HSA-6802957
MAPK1 (ERK2) activation R-HSA-112411
Interleukin-20 family signaling R-HSA-8854691
Signaling by Erythropoietin R-HSA-9006335
Interferon gamma signaling R-HSA-877300
Hemostasis R-HSA-109582
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Interleukin-2 family signaling R-HSA-451927
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Erythropoietin activates RAS R-HSA-9027284
Prolactin receptor signaling R-HSA-1170546
Regulation of IFNG signaling R-HSA-877312
Interleukin-27 signaling R-HSA-9020956
RAF/MAP kinase cascade R-HSA-5673001
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Growth hormone receptor signaling R-HSA-982772
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by KIT in disease R-HSA-9669938
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
SARS-CoV Infections R-HSA-9679506
RMTs methylate histone arginines R-HSA-3214858
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Chromatin organization R-HSA-4839726
Signaling by RAS mutants R-HSA-6802949
Infectious disease R-HSA-5663205
Interferon Signaling R-HSA-913531
Interleukin-12 family signaling R-HSA-447115
Potential therapeutics for SARS R-HSA-9679191
Mitotic G1 phase and G1/S transition R-HSA-453279
Erythropoietin activates STAT5 R-HSA-9027283
MAPK family signaling cascades R-HSA-5683057
Cell Cycle R-HSA-1640170
Interleukin-35 Signalling R-HSA-8984722
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
MAPK3 (ERK1) activation R-HSA-110056
RAF activation R-HSA-5673000
G1 Phase R-HSA-69236
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Disease R-HSA-1643685
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Infectious disease R-HSA-5663205
Cell Cycle, Mitotic R-HSA-69278
Interferon Signaling R-HSA-913531
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-23 signaling R-HSA-9020933
G1 Phase R-HSA-69236
Potential therapeutics for SARS R-HSA-9679191
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-12 family signaling R-HSA-447115
Signaling by KIT in disease R-HSA-9669938
Disease R-HSA-1643685
Interleukin-12 signaling R-HSA-9020591
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signal Transduction R-HSA-162582
Interleukin-35 Signalling R-HSA-8984722
Chromatin organization R-HSA-4839726
Cyclin D associated events in G1 R-HSA-69231
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Signaling by RAF1 mutants R-HSA-9656223
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Oncogenic MAPK signaling R-HSA-6802957
Interleukin receptor SHC signaling R-HSA-912526
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
RMTs methylate histone arginines R-HSA-3214858
Chromatin modifying enzymes R-HSA-3247509
MAPK3 (ERK1) activation R-HSA-110056
RAF activation R-HSA-5673000
Signaling by Interleukins R-HSA-449147
Cell Cycle R-HSA-1640170
Signaling by Erythropoietin R-HSA-9006335
Hemostasis R-HSA-109582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by CSF3 (G-CSF) R-HSA-9674555
Growth hormone receptor signaling R-HSA-982772
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Interleukin-20 family signaling R-HSA-8854691
Mitotic G1 phase and G1/S transition R-HSA-453279
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of IFNG signaling R-HSA-877312
Prolactin receptor signaling R-HSA-1170546
MAPK1 (ERK2) activation R-HSA-112411
Interleukin-27 signaling R-HSA-9020956
MAPK family signaling cascades R-HSA-5683057
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
RAF-independent MAPK1/3 activation R-HSA-112409
RAF/MAP kinase cascade R-HSA-5673001
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Interleukin-6 family signaling R-HSA-6783589
Interleukin-6 signaling R-HSA-1059683
SARS-CoV Infections R-HSA-9679506
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Interleukin-2 family signaling R-HSA-451927
MAPK1/MAPK3 signaling R-HSA-5684996
Interferon gamma signaling R-HSA-877300
Signaling by SCF-KIT R-HSA-1433557
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Immune System R-HSA-168256
Erythropoietin activates RAS R-HSA-9027284
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by RAS mutants R-HSA-6802949
Signaling by Leptin R-HSA-2586552
Erythropoietin activates STAT5 R-HSA-9027283
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Growth hormone receptor signaling R-HSA-982772
Signaling by KIT in disease R-HSA-9669938
Interleukin-20 family signaling R-HSA-8854691
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Disease R-HSA-1643685
Interleukin-6 family signaling R-HSA-6783589
Interleukin-2 family signaling R-HSA-451927
Interleukin-12 signaling R-HSA-9020591
Interleukin-6 signaling R-HSA-1059683
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Interleukin receptor SHC signaling R-HSA-912526
Erythropoietin activates STAT5 R-HSA-9027283
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Chromatin organization R-HSA-4839726
Signal Transduction R-HSA-162582
G1 Phase R-HSA-69236
Interleukin-27 signaling R-HSA-9020956
Prolactin receptor signaling R-HSA-1170546
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-12 family signaling R-HSA-447115
Signaling by Interleukins R-HSA-449147
Signaling downstream of RAS mutants R-HSA-9649948
Immune System R-HSA-168256
MAPK1 (ERK2) activation R-HSA-112411
Cell Cycle R-HSA-1640170
Signaling by Erythropoietin R-HSA-9006335
RMTs methylate histone arginines R-HSA-3214858
Interleukin-23 signaling R-HSA-9020933
Infectious disease R-HSA-5663205
RAF activation R-HSA-5673000
Signaling by Leptin R-HSA-2586552
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Hemostasis R-HSA-109582
Interferon gamma signaling R-HSA-877300
Interleukin-35 Signalling R-HSA-8984722
MAPK1/MAPK3 signaling R-HSA-5684996
Cyclin D associated events in G1 R-HSA-69231
Signaling by RAS mutants R-HSA-6802949
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
Potential therapeutics for SARS R-HSA-9679191
MAPK family signaling cascades R-HSA-5683057
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Regulation of IFNG signaling R-HSA-877312
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
SARS-CoV Infections R-HSA-9679506
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Interferon Signaling R-HSA-913531
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK3 (ERK1) activation R-HSA-110056
Erythropoietin activates RAS R-HSA-9027284
Signaling by RAF1 mutants R-HSA-9656223
Chromatin modifying enzymes R-HSA-3247509
Oncogenic MAPK signaling R-HSA-6802957
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by SCF-KIT R-HSA-1433557
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Interleukin-6 signaling R-HSA-1059683
Chromatin organization R-HSA-4839726
Signaling by KIT in disease R-HSA-9669938
Interleukin-23 signaling R-HSA-9020933
RAF activation R-HSA-5673000
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Mitotic G1 phase and G1/S transition R-HSA-453279
MAPK1 (ERK2) activation R-HSA-112411
Interferon Signaling R-HSA-913531
Signaling by RAS mutants R-HSA-6802949
Interferon gamma signaling R-HSA-877300
Infectious disease R-HSA-5663205
MAPK1/MAPK3 signaling R-HSA-5684996
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
RAF-independent MAPK1/3 activation R-HSA-112409
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Interleukin-2 family signaling R-HSA-451927
Interleukin-35 Signalling R-HSA-8984722
Interleukin-12 signaling R-HSA-9020591
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Potential therapeutics for SARS R-HSA-9679191
Signaling by Interleukins R-HSA-449147
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Prolactin receptor signaling R-HSA-1170546
Regulation of IFNG signaling R-HSA-877312
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Signaling by Leptin R-HSA-2586552
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Interleukin-12 family signaling R-HSA-447115
Erythropoietin activates STAT5 R-HSA-9027283
Signaling downstream of RAS mutants R-HSA-9649948
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Hemostasis R-HSA-109582
Interleukin-20 family signaling R-HSA-8854691
Signaling by RAF1 mutants R-HSA-9656223
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cyclin D associated events in G1 R-HSA-69231
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by CSF3 (G-CSF) R-HSA-9674555
Disease R-HSA-1643685
Interleukin-27 signaling R-HSA-9020956
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
Growth hormone receptor signaling R-HSA-982772
RMTs methylate histone arginines R-HSA-3214858
SARS-CoV Infections R-HSA-9679506
Interleukin receptor SHC signaling R-HSA-912526
Oncogenic MAPK signaling R-HSA-6802957
Cell Cycle R-HSA-1640170
Chromatin modifying enzymes R-HSA-3247509
Signaling by SCF-KIT R-HSA-1433557
Interleukin-6 family signaling R-HSA-6783589
Erythropoietin activates RAS R-HSA-9027284
Immune System R-HSA-168256
Signaling by Erythropoietin R-HSA-9006335

Expression Atlas ENSG00000096968
LRG display in Ensembl gene LRG_612
NCBI gene (formerly Entrezgene) 3717
GeneCards 6192
HGNC Symbol HGNC:6192
MIM gene 147796
MIM morbid 614521
UniProtKB Gene Name O60674
WikiGene 3717
Gene: INSR
Ensembl ID : ENSG00000171105
Description: insulin receptor
Gene Synonyms: CD220
36 APIs:
290 Possible Orthologues:

Signaling by Insulin receptor R-HSA-74752
PIP3 activates AKT signaling R-HSA-1257604
IRS activation R-HSA-74713
Signal attenuation R-HSA-74749
Insulin receptor recycling R-HSA-77387
Insulin receptor signalling cascade R-HSA-74751
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor recycling R-HSA-77387
IRS activation R-HSA-74713
Signaling by Insulin receptor R-HSA-74752
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
PIP3 activates AKT signaling R-HSA-1257604
Signal attenuation R-HSA-74749
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Insulin receptor signalling cascade R-HSA-74751
Signaling by Insulin receptor R-HSA-74752
Signal Transduction R-HSA-162582
Insulin receptor recycling R-HSA-77387
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal attenuation R-HSA-74749
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
IRS activation R-HSA-74713
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
Signaling by Insulin receptor R-HSA-74752
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
IRS activation R-HSA-74713
Negative regulation of the PI3K/AKT network R-HSA-199418
Insulin receptor recycling R-HSA-77387
Signal attenuation R-HSA-74749
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PIP3 activates AKT signaling R-HSA-1257604
Insulin receptor recycling R-HSA-77387
Signal attenuation R-HSA-74749
Insulin receptor signalling cascade R-HSA-74751
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Insulin receptor R-HSA-74752
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
PIP3 activates AKT signaling R-HSA-1257604
IRS activation R-HSA-74713
IRS activation R-HSA-74713
Signal Transduction R-HSA-162582
Insulin receptor signalling cascade R-HSA-74751
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Insulin receptor R-HSA-74752
Insulin receptor recycling R-HSA-77387
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal attenuation R-HSA-74749
PIP3 activates AKT signaling R-HSA-1257604
Insulin receptor signalling cascade R-HSA-74751
Signal attenuation R-HSA-74749
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS activation R-HSA-74713
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor recycling R-HSA-77387
Negative regulation of the PI3K/AKT network R-HSA-199418
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
Signal Transduction R-HSA-162582
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal attenuation R-HSA-74749
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IRS activation R-HSA-74713
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
Insulin receptor recycling R-HSA-77387
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal attenuation R-HSA-74749
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PIP3 activates AKT signaling R-HSA-1257604
Insulin receptor signalling cascade R-HSA-74751
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Insulin receptor recycling R-HSA-77387
IRS activation R-HSA-74713
Signaling by Insulin receptor R-HSA-74752

Expression Atlas ENSG00000171105
NCBI gene (formerly Entrezgene) 3643
GeneCards 6091
HGNC Symbol HGNC:6091
MIM gene 147670
MIM morbid 610549
UniProtKB Gene Name P06213
WikiGene 3643
Gene: SYK
Ensembl ID : ENSG00000165025
Description: spleen associated tyrosine kinase
Gene Synonyms:
14 APIs:
203 Possible Orthologues:

Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Infectious disease R-HSA-5663205
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
FCERI mediated MAPK activation R-HSA-2871796
Disease R-HSA-1643685
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of signaling by CBL R-HSA-912631
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
FCERI mediated Ca+2 mobilization R-HSA-2871809
FLT3 Signaling R-HSA-9607240
Dectin-2 family R-HSA-5621480
DAP12 signaling R-HSA-2424491
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
GPVI-mediated activation cascade R-HSA-114604
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Parasite infection R-HSA-9664407
CLEC7A (Dectin-1) signaling R-HSA-5607764
Leishmania phagocytosis R-HSA-9664417
SARS-CoV Infections R-HSA-9679506
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Interleukin-2 family signaling R-HSA-451927
C-type lectin receptors (CLRs) R-HSA-5621481
Interleukin-2 signaling R-HSA-9020558
Hemostasis R-HSA-109582
Signaling by CSF3 (G-CSF) R-HSA-9674555
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Platelet Aggregation (Plug Formation) R-HSA-76009
DAP12 interactions R-HSA-2172127
Leishmania infection R-HSA-9658195
Signal Transduction R-HSA-162582
FCGR activation R-HSA-2029481
Leishmania parasite growth and survival R-HSA-9664433
Integrin signaling R-HSA-354192
FCGR3A-mediated phagocytosis R-HSA-9664422
Potential therapeutics for SARS R-HSA-9679191
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Cytokine Signaling in Immune system R-HSA-1280215
FLT3 signaling through SRC family kinases R-HSA-9706374
Role of phospholipids in phagocytosis R-HSA-2029485
FCGR activation R-HSA-2029481
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hemostasis R-HSA-109582
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Dectin-2 family R-HSA-5621480
Regulation of signaling by CBL R-HSA-912631
Signaling by Interleukins R-HSA-449147
Interleukin-2 family signaling R-HSA-451927
Cytokine Signaling in Immune system R-HSA-1280215
GPVI-mediated activation cascade R-HSA-114604
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
CLEC7A (Dectin-1) signaling R-HSA-5607764
FCERI mediated MAPK activation R-HSA-2871796
Potential therapeutics for SARS R-HSA-9679191
Role of phospholipids in phagocytosis R-HSA-2029485
Innate Immune System R-HSA-168249
Leishmania infection R-HSA-9658195
Leishmania phagocytosis R-HSA-9664417
FCERI mediated Ca+2 mobilization R-HSA-2871809
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
DAP12 interactions R-HSA-2172127
SARS-CoV Infections R-HSA-9679506
FLT3 signaling through SRC family kinases R-HSA-9706374
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
FLT3 Signaling R-HSA-9607240
Platelet activation, signaling and aggregation R-HSA-76002
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Leishmania parasite growth and survival R-HSA-9664433
DAP12 signaling R-HSA-2424491
Infectious disease R-HSA-5663205
Integrin signaling R-HSA-354192
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-2 signaling R-HSA-9020558
Platelet Aggregation (Plug Formation) R-HSA-76009
Parasite infection R-HSA-9664407
FCGR3A-mediated phagocytosis R-HSA-9664422
Leishmania phagocytosis R-HSA-9664417
Platelet activation, signaling and aggregation R-HSA-76002
FCGR3A-mediated phagocytosis R-HSA-9664422
Regulation of signaling by CBL R-HSA-912631
Interleukin-2 signaling R-HSA-9020558
FLT3 Signaling R-HSA-9607240
Adaptive Immune System R-HSA-1280218
DAP12 interactions R-HSA-2172127
FCERI mediated Ca+2 mobilization R-HSA-2871809
Role of phospholipids in phagocytosis R-HSA-2029485
Signal Transduction R-HSA-162582
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
SARS-CoV Infections R-HSA-9679506
GPVI-mediated activation cascade R-HSA-114604
DAP12 signaling R-HSA-2424491
Leishmania infection R-HSA-9658195
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Dectin-2 family R-HSA-5621480
Innate Immune System R-HSA-168249
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Leishmania parasite growth and survival R-HSA-9664433
Potential therapeutics for SARS R-HSA-9679191
Platelet Aggregation (Plug Formation) R-HSA-76009
Cytokine Signaling in Immune system R-HSA-1280215
Infectious disease R-HSA-5663205
FCERI mediated MAPK activation R-HSA-2871796
C-type lectin receptors (CLRs) R-HSA-5621481
Integrin signaling R-HSA-354192
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by CSF3 (G-CSF) R-HSA-9674555
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Immune System R-HSA-168256
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Interleukin-2 family signaling R-HSA-451927
Disease R-HSA-1643685
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Parasite infection R-HSA-9664407
Signaling by Interleukins R-HSA-449147
Hemostasis R-HSA-109582
FLT3 signaling through SRC family kinases R-HSA-9706374
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
FCGR activation R-HSA-2029481
Signal Transduction R-HSA-162582
Signaling by Interleukins R-HSA-449147
Interleukin-2 signaling R-HSA-9020558
Leishmania parasite growth and survival R-HSA-9664433
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated MAPK activation R-HSA-2871796
Innate Immune System R-HSA-168249
SARS-CoV Infections R-HSA-9679506
FLT3 Signaling R-HSA-9607240
FCGR activation R-HSA-2029481
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
FLT3 signaling through SRC family kinases R-HSA-9706374
C-type lectin receptors (CLRs) R-HSA-5621481
GPVI-mediated activation cascade R-HSA-114604
FCGR3A-mediated IL10 synthesis R-HSA-9664323
FCGR3A-mediated phagocytosis R-HSA-9664422
Integrin signaling R-HSA-354192
Platelet Aggregation (Plug Formation) R-HSA-76009
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Interleukin-2 family signaling R-HSA-451927
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
FCERI mediated Ca+2 mobilization R-HSA-2871809
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Potential therapeutics for SARS R-HSA-9679191
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Platelet activation, signaling and aggregation R-HSA-76002
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of signaling by CBL R-HSA-912631
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Dectin-2 family R-HSA-5621480
Hemostasis R-HSA-109582
Disease R-HSA-1643685
DAP12 interactions R-HSA-2172127
Leishmania phagocytosis R-HSA-9664417
DAP12 signaling R-HSA-2424491
Signaling by CSF3 (G-CSF) R-HSA-9674555
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Infectious disease R-HSA-5663205
Immune System R-HSA-168256
Role of phospholipids in phagocytosis R-HSA-2029485
Leishmania infection R-HSA-9658195
Parasite infection R-HSA-9664407
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
FLT3 signaling through SRC family kinases R-HSA-9706374
Adaptive Immune System R-HSA-1280218
FCGR activation R-HSA-2029481
Disease R-HSA-1643685
Signaling by Interleukins R-HSA-449147
FCGR3A-mediated phagocytosis R-HSA-9664422
DAP12 signaling R-HSA-2424491
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
FCERI mediated Ca+2 mobilization R-HSA-2871809
Leishmania phagocytosis R-HSA-9664417
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
FLT3 Signaling R-HSA-9607240
Interleukin-2 signaling R-HSA-9020558
Infectious disease R-HSA-5663205
Hemostasis R-HSA-109582
Parasite infection R-HSA-9664407
CLEC7A (Dectin-1) signaling R-HSA-5607764
Potential therapeutics for SARS R-HSA-9679191
Leishmania infection R-HSA-9658195
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of signaling by CBL R-HSA-912631
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
FCERI mediated MAPK activation R-HSA-2871796
Signaling by CSF3 (G-CSF) R-HSA-9674555
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Role of phospholipids in phagocytosis R-HSA-2029485
C-type lectin receptors (CLRs) R-HSA-5621481
Cytokine Signaling in Immune system R-HSA-1280215
Dectin-2 family R-HSA-5621480
Leishmania parasite growth and survival R-HSA-9664433
Immune System R-HSA-168256
Platelet Aggregation (Plug Formation) R-HSA-76009
Signal Transduction R-HSA-162582
Integrin signaling R-HSA-354192
GPVI-mediated activation cascade R-HSA-114604
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Interleukin-2 family signaling R-HSA-451927
DAP12 interactions R-HSA-2172127
SARS-CoV Infections R-HSA-9679506
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Role of phospholipids in phagocytosis R-HSA-2029485
FCERI mediated MAPK activation R-HSA-2871796
Infectious disease R-HSA-5663205
DAP12 signaling R-HSA-2424491
GPVI-mediated activation cascade R-HSA-114604
Platelet Aggregation (Plug Formation) R-HSA-76009
Interleukin-2 signaling R-HSA-9020558
CLEC7A (Dectin-1) signaling R-HSA-5607764
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Leishmania parasite growth and survival R-HSA-9664433
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Signaling by CSF3 (G-CSF) R-HSA-9674555
Innate Immune System R-HSA-168249
Hemostasis R-HSA-109582
SARS-CoV Infections R-HSA-9679506
Leishmania phagocytosis R-HSA-9664417
Potential therapeutics for SARS R-HSA-9679191
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Dectin-2 family R-HSA-5621480
DAP12 interactions R-HSA-2172127
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
FCGR activation R-HSA-2029481
FLT3 signaling through SRC family kinases R-HSA-9706374
Adaptive Immune System R-HSA-1280218
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Disease R-HSA-1643685
Platelet activation, signaling and aggregation R-HSA-76002
C-type lectin receptors (CLRs) R-HSA-5621481
FCGR3A-mediated phagocytosis R-HSA-9664422
FCERI mediated Ca+2 mobilization R-HSA-2871809
Leishmania infection R-HSA-9658195
Interleukin-2 family signaling R-HSA-451927
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signal Transduction R-HSA-162582
FLT3 Signaling R-HSA-9607240
Parasite infection R-HSA-9664407
Regulation of signaling by CBL R-HSA-912631
Signaling by Interleukins R-HSA-449147
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Immune System R-HSA-168256
Integrin signaling R-HSA-354192
Signaling by Interleukins R-HSA-449147
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Integrin signaling R-HSA-354192
Signaling by CSF3 (G-CSF) R-HSA-9674555
Cytokine Signaling in Immune system R-HSA-1280215
Role of phospholipids in phagocytosis R-HSA-2029485
DAP12 interactions R-HSA-2172127
Leishmania parasite growth and survival R-HSA-9664433
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
C-type lectin receptors (CLRs) R-HSA-5621481
Dectin-2 family R-HSA-5621480
Platelet Aggregation (Plug Formation) R-HSA-76009
Signal Transduction R-HSA-162582
FLT3 Signaling R-HSA-9607240
Parasite infection R-HSA-9664407
FCGR3A-mediated phagocytosis R-HSA-9664422
FCERI mediated MAPK activation R-HSA-2871796
Innate Immune System R-HSA-168249
GPVI-mediated activation cascade R-HSA-114604
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Infectious disease R-HSA-5663205
Hemostasis R-HSA-109582
SARS-CoV Infections R-HSA-9679506
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
DAP12 signaling R-HSA-2424491
FCGR activation R-HSA-2029481
CLEC7A (Dectin-1) signaling R-HSA-5607764
Leishmania phagocytosis R-HSA-9664417
FCERI mediated Ca+2 mobilization R-HSA-2871809
Leishmania infection R-HSA-9658195
Disease R-HSA-1643685
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Adaptive Immune System R-HSA-1280218
FLT3 signaling through SRC family kinases R-HSA-9706374
Platelet activation, signaling and aggregation R-HSA-76002
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Interleukin-2 family signaling R-HSA-451927
Potential therapeutics for SARS R-HSA-9679191
Interleukin-2 signaling R-HSA-9020558
Regulation of signaling by CBL R-HSA-912631
Immune System R-HSA-168256
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Regulation of signaling by CBL R-HSA-912631
Hemostasis R-HSA-109582
FCGR3A-mediated phagocytosis R-HSA-9664422
Dectin-2 family R-HSA-5621480
DAP12 signaling R-HSA-2424491
Infectious disease R-HSA-5663205
Potential therapeutics for SARS R-HSA-9679191
Platelet activation, signaling and aggregation R-HSA-76002
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Immune System R-HSA-168256
CLEC7A (Dectin-1) signaling R-HSA-5607764
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FLT3 Signaling R-HSA-9607240
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Interleukin-2 signaling R-HSA-9020558
FCERI mediated Ca+2 mobilization R-HSA-2871809
Leishmania phagocytosis R-HSA-9664417
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-2 family signaling R-HSA-451927
Innate Immune System R-HSA-168249
Leishmania infection R-HSA-9658195
Disease R-HSA-1643685
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Signaling by CSF3 (G-CSF) R-HSA-9674555
SARS-CoV Infections R-HSA-9679506
GPVI-mediated activation cascade R-HSA-114604
Signaling by Interleukins R-HSA-449147
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
FCGR activation R-HSA-2029481
Platelet Aggregation (Plug Formation) R-HSA-76009
FCERI mediated MAPK activation R-HSA-2871796
DAP12 interactions R-HSA-2172127
Leishmania parasite growth and survival R-HSA-9664433
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
C-type lectin receptors (CLRs) R-HSA-5621481
Integrin signaling R-HSA-354192
Signal Transduction R-HSA-162582
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Role of phospholipids in phagocytosis R-HSA-2029485
Parasite infection R-HSA-9664407
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
FLT3 signaling through SRC family kinases R-HSA-9706374
Adaptive Immune System R-HSA-1280218
Cytokine Signaling in Immune system R-HSA-1280215
Leishmania parasite growth and survival R-HSA-9664433
Interleukin-2 family signaling R-HSA-451927
FCGR3A-mediated IL10 synthesis R-HSA-9664323
DAP12 interactions R-HSA-2172127
Disease R-HSA-1643685
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
FLT3 signaling through SRC family kinases R-HSA-9706374
Signal Transduction R-HSA-162582
Leishmania infection R-HSA-9658195
SARS-CoV Infections R-HSA-9679506
Interleukin-2 signaling R-HSA-9020558
Platelet Aggregation (Plug Formation) R-HSA-76009
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Platelet activation, signaling and aggregation R-HSA-76002
Adaptive Immune System R-HSA-1280218
Signaling by Interleukins R-HSA-449147
Parasite infection R-HSA-9664407
CLEC7A (Dectin-1) signaling R-HSA-5607764
Integrin signaling R-HSA-354192
FCERI mediated Ca+2 mobilization R-HSA-2871809
FCERI mediated MAPK activation R-HSA-2871796
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
DAP12 signaling R-HSA-2424491
Potential therapeutics for SARS R-HSA-9679191
C-type lectin receptors (CLRs) R-HSA-5621481
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Leishmania phagocytosis R-HSA-9664417
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Infectious disease R-HSA-5663205
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Immune System R-HSA-168256
Signaling by CSF3 (G-CSF) R-HSA-9674555
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cytokine Signaling in Immune system R-HSA-1280215
Hemostasis R-HSA-109582
Role of phospholipids in phagocytosis R-HSA-2029485
Regulation of signaling by CBL R-HSA-912631
Dectin-2 family R-HSA-5621480
GPVI-mediated activation cascade R-HSA-114604
FLT3 Signaling R-HSA-9607240
FCGR activation R-HSA-2029481
FCGR3A-mediated phagocytosis R-HSA-9664422
Innate Immune System R-HSA-168249
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Signaling by CSF3 (G-CSF) R-HSA-9674555
Leishmania parasite growth and survival R-HSA-9664433
FLT3 signaling through SRC family kinases R-HSA-9706374
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Integrin signaling R-HSA-354192
Role of phospholipids in phagocytosis R-HSA-2029485
SARS-CoV Infections R-HSA-9679506
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
DAP12 signaling R-HSA-2424491
Innate Immune System R-HSA-168249
DAP12 interactions R-HSA-2172127
Regulation of signaling by CBL R-HSA-912631
Interleukin-2 family signaling R-HSA-451927
Leishmania infection R-HSA-9658195
Platelet activation, signaling and aggregation R-HSA-76002
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hemostasis R-HSA-109582
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
FCERI mediated Ca+2 mobilization R-HSA-2871809
Leishmania phagocytosis R-HSA-9664417
FCERI mediated MAPK activation R-HSA-2871796
Interleukin-2 signaling R-HSA-9020558
Signal Transduction R-HSA-162582
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
CLEC7A (Dectin-1) signaling R-HSA-5607764
FCGR activation R-HSA-2029481
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
Immune System R-HSA-168256
FLT3 Signaling R-HSA-9607240
Platelet Aggregation (Plug Formation) R-HSA-76009
GPVI-mediated activation cascade R-HSA-114604
FCGR3A-mediated IL10 synthesis R-HSA-9664323
C-type lectin receptors (CLRs) R-HSA-5621481
Dectin-2 family R-HSA-5621480
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Potential therapeutics for SARS R-HSA-9679191
Adaptive Immune System R-HSA-1280218
Parasite infection R-HSA-9664407

Expression Atlas ENSG00000165025
NCBI gene (formerly Entrezgene) 6850
GeneCards 11491
HGNC Symbol HGNC:11491
MIM gene 600085
MIM morbid 619381
UniProtKB Gene Name P43405
WikiGene 6850
Gene: RET
Ensembl ID : ENSG00000165731
Description: ret proto-oncogene
Gene Synonyms: CDHF12,CDHR16,HSCR1,MEN2A,MEN2B,MTC1,PTC,RET51
14 APIs:
205 Possible Orthologues:

Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
NPAS4 regulates expression of target genes R-HSA-9768919
Developmental Biology R-HSA-1266738
RET signaling R-HSA-8853659
Axon guidance R-HSA-422475
Transcriptional Regulation by NPAS4 R-HSA-9634815
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
NPAS4 regulates expression of target genes R-HSA-9768919
MAPK1/MAPK3 signaling R-HSA-5684996
RET signaling R-HSA-8853659
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by NPAS4 R-HSA-9634815
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
MAPK family signaling cascades R-HSA-5683057
Generic Transcription Pathway R-HSA-212436
RAF/MAP kinase cascade R-HSA-5673001
NPAS4 regulates expression of target genes R-HSA-9768919
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Nervous system development R-HSA-9675108
MAPK family signaling cascades R-HSA-5683057
RET signaling R-HSA-8853659
Axon guidance R-HSA-422475
Transcriptional Regulation by NPAS4 R-HSA-9634815
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
NPAS4 regulates expression of target genes R-HSA-9768919
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
Developmental Biology R-HSA-1266738
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Transcriptional Regulation by NPAS4 R-HSA-9634815
RNA Polymerase II Transcription R-HSA-73857
RET signaling R-HSA-8853659
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Transcriptional Regulation by NPAS4 R-HSA-9634815
NPAS4 regulates expression of target genes R-HSA-9768919
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
RET signaling R-HSA-8853659
Generic Transcription Pathway R-HSA-212436
Nervous system development R-HSA-9675108
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Nervous system development R-HSA-9675108
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
RET signaling R-HSA-8853659
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
NPAS4 regulates expression of target genes R-HSA-9768919
Transcriptional Regulation by NPAS4 R-HSA-9634815
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
RET signaling R-HSA-8853659
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
NPAS4 regulates expression of target genes R-HSA-9768919
RAF/MAP kinase cascade R-HSA-5673001
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Transcriptional Regulation by NPAS4 R-HSA-9634815
Axon guidance R-HSA-422475
NPAS4 regulates expression of target genes R-HSA-9768919
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
Transcriptional Regulation by NPAS4 R-HSA-9634815
RET signaling R-HSA-8853659
MAPK1/MAPK3 signaling R-HSA-5684996
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Axon guidance R-HSA-422475
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
NPAS4 regulates expression of target genes R-HSA-9768919
RET signaling R-HSA-8853659
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional Regulation by NPAS4 R-HSA-9634815
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
MAPK1/MAPK3 signaling R-HSA-5684996
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
NPAS4 regulates expression of target genes R-HSA-9768919
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
Developmental Biology R-HSA-1266738
RET signaling R-HSA-8853659
Transcriptional Regulation by NPAS4 R-HSA-9634815
Nervous system development R-HSA-9675108
RAF/MAP kinase cascade R-HSA-5673001
NPAS4 regulates expression of target genes R-HSA-9768919
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by NPAS4 R-HSA-9634815
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
RET signaling R-HSA-8853659

Expression Atlas ENSG00000165731
LRG display in Ensembl gene LRG_518
NCBI gene (formerly Entrezgene) 5979
GeneCards 9967
HGNC Symbol HGNC:9967
MIM gene 164761
MIM morbid 171400
UniProtKB Gene Name P07949
WikiGene 5979