Gene: PSENEN
Ensembl ID : ENSG00000205155
Description: presenilin enhancer, gamma-secretase subunit
Gene Synonyms: PEN2
5 APIs:
185 Possible Orthologues:

Signaling by ERBB4 R-HSA-1236394
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH1 R-HSA-1980143
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
p75 NTR receptor-mediated signalling R-HSA-193704
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH4 R-HSA-9013694
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Regulated proteolysis of p75NTR R-HSA-193692
Amyloid fiber formation R-HSA-977225
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH2 R-HSA-1980145
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-Ephrin signaling R-HSA-2682334
Signaling by ERBB4 R-HSA-1236394
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulated proteolysis of p75NTR R-HSA-193692
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Developmental Biology R-HSA-1266738
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH2 R-HSA-1980145
Disease R-HSA-1643685
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 R-HSA-1980143
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Amyloid fiber formation R-HSA-977225
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH4 R-HSA-9013694
Noncanonical activation of NOTCH3 R-HSA-9017802
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Axon guidance R-HSA-422475
Metabolism of proteins R-HSA-392499
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
p75 NTR receptor-mediated signalling R-HSA-193704
Nervous system development R-HSA-9675108
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH2 R-HSA-1980145
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Noncanonical activation of NOTCH3 R-HSA-9017802
Death Receptor Signaling R-HSA-73887
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
Nervous system development R-HSA-9675108
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
Nuclear signaling by ERBB4 R-HSA-1251985
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 in Cancer R-HSA-2644603
NRIF signals cell death from the nucleus R-HSA-205043
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
p75 NTR receptor-mediated signalling R-HSA-193704
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH R-HSA-157118
Regulated proteolysis of p75NTR R-HSA-193692
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
EPH-Ephrin signaling R-HSA-2682334
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear signaling by ERBB4 R-HSA-1251985
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH3 R-HSA-9012852
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH2 R-HSA-1980145
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by ERBB4 R-HSA-1236394
Amyloid fiber formation R-HSA-977225
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Death Receptor Signaling R-HSA-73887
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by ERBB4 R-HSA-1236394
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH3 R-HSA-9012852
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Death Receptor Signaling R-HSA-73887
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Regulated proteolysis of p75NTR R-HSA-193692
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH4 R-HSA-9013694
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH2 R-HSA-1980145
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 R-HSA-1980143
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
EPH-Ephrin signaling R-HSA-2682334
Nuclear signaling by ERBB4 R-HSA-1251985
Nuclear signaling by ERBB4 R-HSA-1251985
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
Signaling by ERBB4 R-HSA-1236394
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH3 R-HSA-9012852
Disease R-HSA-1643685
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH4 R-HSA-9013694
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Nervous system development R-HSA-9675108
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Amyloid fiber formation R-HSA-977225
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH2 R-HSA-1980145
Axon guidance R-HSA-422475
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-Ephrin signaling R-HSA-2682334
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH R-HSA-157118
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH2 R-HSA-1980145
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH3 R-HSA-9012852
Noncanonical activation of NOTCH3 R-HSA-9017802
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nervous system development R-HSA-9675108
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Death Receptor Signaling R-HSA-73887
EPH-Ephrin signaling R-HSA-2682334
Metabolism of proteins R-HSA-392499
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Axon guidance R-HSA-422475
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NRIF signals cell death from the nucleus R-HSA-205043
Death Receptor Signaling R-HSA-73887
Disease R-HSA-1643685
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Amyloid fiber formation R-HSA-977225
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 in Cancer R-HSA-2644603
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH3 R-HSA-9012852
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signal Transduction R-HSA-162582
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by ERBB4 R-HSA-1236394
Metabolism of proteins R-HSA-392499
Signaling by NOTCH2 R-HSA-1980145
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 R-HSA-1980143
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Developmental Biology R-HSA-1266738
Noncanonical activation of NOTCH3 R-HSA-9017802
Nervous system development R-HSA-9675108
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Regulated proteolysis of p75NTR R-HSA-193692
Signal Transduction R-HSA-162582
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-Ephrin signaling R-HSA-2682334
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Death Receptor Signaling R-HSA-73887
Metabolism of proteins R-HSA-392499
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH3 R-HSA-9012852
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH R-HSA-157118
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Axon guidance R-HSA-422475
Signaling by NOTCH2 R-HSA-1980145
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 R-HSA-1980143
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 in Cancer R-HSA-2644603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by NOTCH1 in Cancer R-HSA-2644603
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
Death Receptor Signaling R-HSA-73887
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 R-HSA-1980143
Amyloid fiber formation R-HSA-977225
Disease R-HSA-1643685
Signaling by NOTCH2 R-HSA-1980145
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH3 R-HSA-9012852
Nervous system development R-HSA-9675108
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by ERBB4 R-HSA-1236394
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH4 R-HSA-9013694
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NRIF signals cell death from the nucleus R-HSA-205043
p75 NTR receptor-mediated signalling R-HSA-193704
EPH-Ephrin signaling R-HSA-2682334
Axon guidance R-HSA-422475
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Signaling by ERBB4 R-HSA-1236394
Nuclear signaling by ERBB4 R-HSA-1251985
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 in Cancer R-HSA-2644603
EPH-Ephrin signaling R-HSA-2682334
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
Disease R-HSA-1643685
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Amyloid fiber formation R-HSA-977225

Expression Atlas ENSG00000205155
LRG display in Ensembl gene LRG_222
NCBI gene (formerly Entrezgene) 55851
GeneCards 30100
HGNC Symbol HGNC:30100
MIM gene 607632
MIM morbid 613736
UniProtKB Gene Name Q9NZ42
WikiGene 55851
Gene: F2RL3
Ensembl ID : ENSG00000127533
Description: F2R like thrombin or trypsin receptor 3
Gene Synonyms: PAR4
1 APIs:
193 Possible Orthologues:

Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Hemostasis R-HSA-109582
G alpha (q) signalling events R-HSA-416476
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Hemostasis R-HSA-109582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by GPCR R-HSA-372790
Hemostasis R-HSA-109582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
G alpha (q) signalling events R-HSA-416476
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
G alpha (q) signalling events R-HSA-416476
Platelet activation, signaling and aggregation R-HSA-76002
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
Peptide ligand-binding receptors R-HSA-375276
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
GPCR ligand binding R-HSA-500792
Hemostasis R-HSA-109582
Signaling by GPCR R-HSA-372790
Platelet activation, signaling and aggregation R-HSA-76002
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
Platelet activation, signaling and aggregation R-HSA-76002
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
G alpha (q) signalling events R-HSA-416476
G alpha (q) signalling events R-HSA-416476
Hemostasis R-HSA-109582
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
Platelet activation, signaling and aggregation R-HSA-76002
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Class A/1 (Rhodopsin-like receptors) R-HSA-373076

Expression Atlas ENSG00000127533
LRG display in Ensembl gene LRG_633
NCBI gene (formerly Entrezgene) 9002
GeneCards 3540
HGNC Symbol HGNC:3540
MIM gene 602779
UniProtKB Gene Name Q96RI0
WikiGene 9002
Gene: F2R
Ensembl ID : ENSG00000181104
Description: coagulation factor II thrombin receptor
Gene Synonyms: CF2R,PAR-1,PAR1,TR
3 APIs:
330 Possible Orthologues:

GPCR downstream signalling R-HSA-388396
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Common Pathway of Fibrin Clot Formation R-HSA-140875
G alpha (q) signalling events R-HSA-416476
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Platelet activation, signaling and aggregation R-HSA-76002
Peptide ligand-binding receptors R-HSA-375276
Hemostasis R-HSA-109582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Peptide ligand-binding receptors R-HSA-375276
Common Pathway of Fibrin Clot Formation R-HSA-140875
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Platelet activation, signaling and aggregation R-HSA-76002
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
Hemostasis R-HSA-109582
Common Pathway of Fibrin Clot Formation R-HSA-140875
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Common Pathway of Fibrin Clot Formation R-HSA-140875
Platelet activation, signaling and aggregation R-HSA-76002
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Signaling by GPCR R-HSA-372790
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Hemostasis R-HSA-109582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Common Pathway of Fibrin Clot Formation R-HSA-140875
G alpha (q) signalling events R-HSA-416476
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
GPCR ligand binding R-HSA-500792
Platelet activation, signaling and aggregation R-HSA-76002
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Signaling by GPCR R-HSA-372790
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Common Pathway of Fibrin Clot Formation R-HSA-140875
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Hemostasis R-HSA-109582
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Platelet activation, signaling and aggregation R-HSA-76002
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
Common Pathway of Fibrin Clot Formation R-HSA-140875
GPCR downstream signalling R-HSA-388396
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
GPCR downstream signalling R-HSA-388396
Platelet activation, signaling and aggregation R-HSA-76002
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Common Pathway of Fibrin Clot Formation R-HSA-140875
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Common Pathway of Fibrin Clot Formation R-HSA-140875
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Hemostasis R-HSA-109582
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Peptide ligand-binding receptors R-HSA-375276
G alpha (q) signalling events R-HSA-416476
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
GPCR downstream signalling R-HSA-388396
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Common Pathway of Fibrin Clot Formation R-HSA-140875
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Signaling by GPCR R-HSA-372790

Expression Atlas ENSG00000181104
LRG display in Ensembl gene LRG_641
NCBI gene (formerly Entrezgene) 2149
GeneCards 3537
HGNC Symbol HGNC:3537
MIM gene 187930
UniProtKB Gene Name P25116
WikiGene 2149
Gene: NPR1
Ensembl ID : ENSG00000169418
Description: natriuretic peptide receptor 1
Gene Synonyms: ANPA,ANPRA,GUCY2A,NPRA
3 APIs:
186 Possible Orthologues:

Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Physiological factors R-HSA-5578768
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Physiological factors R-HSA-5578768
Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Physiological factors R-HSA-5578768
Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Physiological factors R-HSA-5578768
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014

Expression Atlas ENSG00000169418
NCBI gene (formerly Entrezgene) 4881
GeneCards 7943
HGNC Symbol HGNC:7943
MIM gene 108960
UniProtKB Gene Name P16066
WikiGene 4881
Gene: NPR3
Ensembl ID : ENSG00000113389
Description: natriuretic peptide receptor 3
Gene Synonyms: ANPRC,C5ORF23,FLJ14054,GUCY2B,NPRC
1 APIs:
210 Possible Orthologues:

Expression Atlas ENSG00000113389
NCBI gene (formerly Entrezgene) 4883
GeneCards 7945
HGNC Symbol HGNC:7945
MIM gene 108962
MIM morbid 619543
UniProtKB Gene Name Q60I31
WikiGene 4883
Gene: NPR2
Ensembl ID : ENSG00000159899
Description: natriuretic peptide receptor 2
Gene Synonyms: AMDM,ANPB,ANPRB,GC-B,GUCY2B,NPRB
1 APIs:
260 Possible Orthologues:

Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Physiological factors R-HSA-5578768
Cardiac conduction R-HSA-5576891
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Physiological factors R-HSA-5578768
Physiological factors R-HSA-5578768
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Muscle contraction R-HSA-397014
Physiological factors R-HSA-5578768
Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Physiological factors R-HSA-5578768
Cardiac conduction R-HSA-5576891
Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768

Expression Atlas ENSG00000159899
NCBI gene (formerly Entrezgene) 4882
GeneCards 7944
HGNC Symbol HGNC:7944
MIM gene 108961
MIM morbid 616255
UniProtKB Gene Name P20594
WikiGene 4882
Gene: SLC5A2
Ensembl ID : ENSG00000140675
Description: solute carrier family 5 member 2
Gene Synonyms: SGLT2
14 APIs:
198 Possible Orthologues:

Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Disorders of transmembrane transporters R-HSA-5619115
SLC-mediated transmembrane transport R-HSA-425407
Defective SLC5A2 causes renal glucosuria (GLYS1) R-HSA-5658208
SLC transporter disorders R-HSA-5619102
Cellular hexose transport R-HSA-189200
Defective SLC5A2 causes renal glucosuria (GLYS1) R-HSA-5658208
Cellular hexose transport R-HSA-189200
SLC-mediated transmembrane transport R-HSA-425407
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
SLC transporter disorders R-HSA-5619102
Disorders of transmembrane transporters R-HSA-5619115
SLC-mediated transmembrane transport R-HSA-425407
Defective SLC5A2 causes renal glucosuria (GLYS1) R-HSA-5658208
Cellular hexose transport R-HSA-189200
SLC transporter disorders R-HSA-5619102
Disorders of transmembrane transporters R-HSA-5619115
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Defective SLC5A2 causes renal glucosuria (GLYS1) R-HSA-5658208
Disorders of transmembrane transporters R-HSA-5619115
SLC transporter disorders R-HSA-5619102
Cellular hexose transport R-HSA-189200
SLC-mediated transmembrane transport R-HSA-425407
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
SLC transporter disorders R-HSA-5619102
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Disorders of transmembrane transporters R-HSA-5619115
Cellular hexose transport R-HSA-189200
SLC-mediated transmembrane transport R-HSA-425407
Defective SLC5A2 causes renal glucosuria (GLYS1) R-HSA-5658208
Cellular hexose transport R-HSA-189200
Disease R-HSA-1643685
SLC-mediated transmembrane transport R-HSA-425407
Transport of small molecules R-HSA-382551
Disorders of transmembrane transporters R-HSA-5619115
Defective SLC5A2 causes renal glucosuria (GLYS1) R-HSA-5658208
SLC transporter disorders R-HSA-5619102
SLC-mediated transmembrane transport R-HSA-425407
SLC transporter disorders R-HSA-5619102
Disorders of transmembrane transporters R-HSA-5619115
Disease R-HSA-1643685
Defective SLC5A2 causes renal glucosuria (GLYS1) R-HSA-5658208
Transport of small molecules R-HSA-382551
Cellular hexose transport R-HSA-189200
Cellular hexose transport R-HSA-189200
Defective SLC5A2 causes renal glucosuria (GLYS1) R-HSA-5658208
Disease R-HSA-1643685
SLC transporter disorders R-HSA-5619102
SLC-mediated transmembrane transport R-HSA-425407
Disorders of transmembrane transporters R-HSA-5619115
Transport of small molecules R-HSA-382551
SLC-mediated transmembrane transport R-HSA-425407
Cellular hexose transport R-HSA-189200
Defective SLC5A2 causes renal glucosuria (GLYS1) R-HSA-5658208
Disease R-HSA-1643685
Disorders of transmembrane transporters R-HSA-5619115
Transport of small molecules R-HSA-382551
SLC transporter disorders R-HSA-5619102
SLC-mediated transmembrane transport R-HSA-425407
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
Cellular hexose transport R-HSA-189200
Disorders of transmembrane transporters R-HSA-5619115
Defective SLC5A2 causes renal glucosuria (GLYS1) R-HSA-5658208
SLC transporter disorders R-HSA-5619102

Expression Atlas ENSG00000140675
NCBI gene (formerly Entrezgene) 6524
GeneCards 11037
HGNC Symbol HGNC:11037
MIM gene 182381
MIM morbid 233100
UniProtKB Gene Name P31639
WikiGene 6524
Gene: SLC5A1
Ensembl ID : ENSG00000100170
Description: solute carrier family 5 member 1
Gene Synonyms: D22S675,NAGT,SGLT-1,SGLT1
2 APIs:
250 Possible Orthologues:

SLC-mediated transmembrane transport R-HSA-425407
Disease R-HSA-1643685
Intestinal absorption R-HSA-8963676
Digestion and absorption R-HSA-8963743
Intestinal hexose absorption R-HSA-8981373
Cellular hexose transport R-HSA-189200
SLC transporter disorders R-HSA-5619102
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
Disorders of transmembrane transporters R-HSA-5619115
Transport of small molecules R-HSA-382551
SLC-mediated transmembrane transport R-HSA-425407
Intestinal hexose absorption R-HSA-8981373
Disease R-HSA-1643685
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
SLC transporter disorders R-HSA-5619102
SLC-mediated transmembrane transport R-HSA-425407
Transport of small molecules R-HSA-382551
Disorders of transmembrane transporters R-HSA-5619115
Digestion and absorption R-HSA-8963743
Intestinal absorption R-HSA-8963676
Cellular hexose transport R-HSA-189200
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
Intestinal absorption R-HSA-8963676
SLC transporter disorders R-HSA-5619102
Transport of small molecules R-HSA-382551
SLC-mediated transmembrane transport R-HSA-425407
Cellular hexose transport R-HSA-189200
Intestinal hexose absorption R-HSA-8981373
Disorders of transmembrane transporters R-HSA-5619115
Digestion and absorption R-HSA-8963743
Disease R-HSA-1643685
SLC transporter disorders R-HSA-5619102
Cellular hexose transport R-HSA-189200
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
Disorders of transmembrane transporters R-HSA-5619115
Transport of small molecules R-HSA-382551
Digestion and absorption R-HSA-8963743
Disease R-HSA-1643685
SLC-mediated transmembrane transport R-HSA-425407
Intestinal absorption R-HSA-8963676
Intestinal hexose absorption R-HSA-8981373
Cellular hexose transport R-HSA-189200
Intestinal hexose absorption R-HSA-8981373
Disease R-HSA-1643685
Disorders of transmembrane transporters R-HSA-5619115
Intestinal absorption R-HSA-8963676
SLC-mediated transmembrane transport R-HSA-425407
SLC transporter disorders R-HSA-5619102
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
Transport of small molecules R-HSA-382551
Digestion and absorption R-HSA-8963743
Disorders of transmembrane transporters R-HSA-5619115
Digestion and absorption R-HSA-8963743
SLC transporter disorders R-HSA-5619102
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
Disease R-HSA-1643685
Intestinal absorption R-HSA-8963676
Intestinal hexose absorption R-HSA-8981373
SLC-mediated transmembrane transport R-HSA-425407
Cellular hexose transport R-HSA-189200
Transport of small molecules R-HSA-382551
Intestinal absorption R-HSA-8963676
Transport of small molecules R-HSA-382551
Disorders of transmembrane transporters R-HSA-5619115
SLC transporter disorders R-HSA-5619102
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
Intestinal hexose absorption R-HSA-8981373
Cellular hexose transport R-HSA-189200
Disease R-HSA-1643685
Digestion and absorption R-HSA-8963743
SLC transporter disorders R-HSA-5619102
Disorders of transmembrane transporters R-HSA-5619115
Digestion and absorption R-HSA-8963743
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
SLC-mediated transmembrane transport R-HSA-425407
Intestinal hexose absorption R-HSA-8981373
Intestinal absorption R-HSA-8963676
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
Cellular hexose transport R-HSA-189200
Transport of small molecules R-HSA-382551
Cellular hexose transport R-HSA-189200
Disease R-HSA-1643685
Intestinal absorption R-HSA-8963676
SLC-mediated transmembrane transport R-HSA-425407
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
SLC transporter disorders R-HSA-5619102
Digestion and absorption R-HSA-8963743
Disorders of transmembrane transporters R-HSA-5619115
Intestinal hexose absorption R-HSA-8981373
SLC-mediated transmembrane transport R-HSA-425407
Intestinal absorption R-HSA-8963676
Cellular hexose transport R-HSA-189200
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) R-HSA-5656364
Transport of small molecules R-HSA-382551
Digestion and absorption R-HSA-8963743
SLC transporter disorders R-HSA-5619102
Disease R-HSA-1643685
Intestinal hexose absorption R-HSA-8981373
Disorders of transmembrane transporters R-HSA-5619115

Expression Atlas ENSG00000100170
NCBI gene (formerly Entrezgene) 6523
GeneCards 11036
HGNC Symbol HGNC:11036
MIM gene 182380
MIM morbid 606824
UniProtKB Gene Name P13866
WikiGene 6523