Gene: FKBP1A
Ensembl ID : ENSG00000088832
Description: FKBP prolyl isomerase 1A
Gene Synonyms: FKBP-12,FKBP1,FKBP12,FKBP12C,PKC12,PPIASE
7 APIs:
159 Possible Orthologues:

Calcineurin activates NFAT R-HSA-2025928
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TGF-beta receptor signaling activates SMADs R-HSA-2173789
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
SARS-CoV-1 Infection R-HSA-9678108
mTORC1-mediated signalling R-HSA-166208
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MTOR signalling R-HSA-165159
Disease R-HSA-1643685
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV Infections R-HSA-9679506
Signal Transduction R-HSA-162582
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by TGFB family members R-HSA-9006936
SARS-CoV-1-host interactions R-HSA-9692914
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Disease R-HSA-1643685
MTOR signalling R-HSA-165159
Adaptive Immune System R-HSA-1280218
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by TGF-beta Receptor Complex R-HSA-170834
Immune System R-HSA-168256
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Infectious disease R-HSA-5663205
mTORC1-mediated signalling R-HSA-166208
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV-1-host interactions R-HSA-9692914
Signaling by TGFB family members R-HSA-9006936
SARS-CoV-1 Infection R-HSA-9678108
Calcineurin activates NFAT R-HSA-2025928
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SARS-CoV Infections R-HSA-9679506
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
MTOR signalling R-HSA-165159
mTORC1-mediated signalling R-HSA-166208
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Calcineurin activates NFAT R-HSA-2025928
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
SARS-CoV-1-host interactions R-HSA-9692914
Infectious disease R-HSA-5663205
SARS-CoV-1 Infection R-HSA-9678108
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Signal Transduction R-HSA-162582
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by TGF-beta Receptor Complex R-HSA-170834
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by TGFB family members R-HSA-9006936
Immune System R-HSA-168256
SARS-CoV Infections R-HSA-9679506
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Disease R-HSA-1643685
Adaptive Immune System R-HSA-1280218
Potential therapeutics for SARS R-HSA-9679191
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
Signaling by TGFB family members R-HSA-9006936
mTORC1-mediated signalling R-HSA-166208
SARS-CoV Infections R-HSA-9679506
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Signal Transduction R-HSA-162582
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Calcineurin activates NFAT R-HSA-2025928
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV-1 Infection R-HSA-9678108
TGF-beta receptor signaling activates SMADs R-HSA-2173789
MTOR signalling R-HSA-165159
Signaling by TGF-beta Receptor Complex R-HSA-170834
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
SARS-CoV-1-host interactions R-HSA-9692914
Signal Transduction R-HSA-162582
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Immune System R-HSA-168256
SARS-CoV Infections R-HSA-9679506
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Adaptive Immune System R-HSA-1280218
Potential therapeutics for SARS R-HSA-9679191
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Calcineurin activates NFAT R-HSA-2025928
Infectious disease R-HSA-5663205
mTORC1-mediated signalling R-HSA-166208
Disease R-HSA-1643685
Signaling by TGF-beta Receptor Complex R-HSA-170834
MTOR signalling R-HSA-165159
Signaling by TGFB family members R-HSA-9006936
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-1-host interactions R-HSA-9692914
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
MTOR signalling R-HSA-165159
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
Calcineurin activates NFAT R-HSA-2025928
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Signal Transduction R-HSA-162582
mTORC1-mediated signalling R-HSA-166208
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Infectious disease R-HSA-5663205
Immune System R-HSA-168256
Signaling by TGFB family members R-HSA-9006936
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV-1-host interactions R-HSA-9692914
Potential therapeutics for SARS R-HSA-9679191
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by TGF-beta Receptor Complex R-HSA-170834
TGF-beta receptor signaling activates SMADs R-HSA-2173789
MTOR signalling R-HSA-165159
Potential therapeutics for SARS R-HSA-9679191
Infectious disease R-HSA-5663205
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Calcineurin activates NFAT R-HSA-2025928
Immune System R-HSA-168256
Signaling by TGFB family members R-HSA-9006936
SARS-CoV-1 Infection R-HSA-9678108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SARS-CoV-1-host interactions R-HSA-9692914
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signal Transduction R-HSA-162582
Signaling by TGF-beta Receptor Complex R-HSA-170834
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
SARS-CoV Infections R-HSA-9679506
mTORC1-mediated signalling R-HSA-166208
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
mTORC1-mediated signalling R-HSA-166208
SARS-CoV Infections R-HSA-9679506
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TGF-beta receptor signaling activates SMADs R-HSA-2173789
SARS-CoV-1-host interactions R-HSA-9692914
Potential therapeutics for SARS R-HSA-9679191
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Signaling by TGF-beta Receptor Complex R-HSA-170834
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Calcineurin activates NFAT R-HSA-2025928
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by TGFB family members R-HSA-9006936
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
SARS-CoV-1 Infection R-HSA-9678108
MTOR signalling R-HSA-165159
Signal Transduction R-HSA-162582
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV-1-host interactions R-HSA-9692914
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by TGF-beta Receptor Complex R-HSA-170834
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
SARS-CoV-1 Infection R-HSA-9678108
Signaling by TGFB family members R-HSA-9006936
SARS-CoV Infections R-HSA-9679506
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Adaptive Immune System R-HSA-1280218
Potential therapeutics for SARS R-HSA-9679191
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
MTOR signalling R-HSA-165159
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Calcineurin activates NFAT R-HSA-2025928
mTORC1-mediated signalling R-HSA-166208
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351

Expression Atlas ENSG00000088832
NCBI gene (formerly Entrezgene) 2280
GeneCards 3711
HGNC Symbol HGNC:3711
MIM gene 186945
UniProtKB Gene Name Q5W0X3
WikiGene 2280
Gene: NPR3
Ensembl ID : ENSG00000113389
Description: natriuretic peptide receptor 3
Gene Synonyms: ANPRC,C5ORF23,FLJ14054,GUCY2B,NPRC
1 APIs:
210 Possible Orthologues:

Expression Atlas ENSG00000113389
NCBI gene (formerly Entrezgene) 4883
GeneCards 7945
HGNC Symbol HGNC:7945
MIM gene 108962
MIM morbid 619543
UniProtKB Gene Name Q60I31
WikiGene 4883
Gene: APP
Ensembl ID : ENSG00000142192
Description: amyloid beta precursor protein
Gene Synonyms: AD1,ALPHA-SAPP
11 APIs:
279 Possible Orthologues:

Hemostasis R-HSA-109582
Signaling by Interleukins R-HSA-449147
Metabolism of proteins R-HSA-392499
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473
MyD88 dependent cascade initiated on endosome R-HSA-975155
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Signal Transduction R-HSA-162582
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Post-translational protein modification R-HSA-597592
Protein localization R-HSA-9609507
Inflammasomes R-HSA-622312
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Platelet degranulation R-HSA-114608
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
The NLRP3 inflammasome R-HSA-844456
Peptide ligand-binding receptors R-HSA-375276
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cytokine Signaling in Immune system R-HSA-1280215
GPCR ligand binding R-HSA-500792
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Interleukin-1 signaling R-HSA-9020702
Post-translational protein phosphorylation R-HSA-8957275
Diseases of programmed cell death R-HSA-9645723
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523
Membrane Trafficking R-HSA-199991
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
trans-Golgi Network Vesicle Budding R-HSA-199992
Interleukin-1 family signaling R-HSA-446652
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Infectious disease R-HSA-5663205
Leishmania infection R-HSA-9658195
Neurodegenerative Diseases R-HSA-8863678
MyD88-independent TLR4 cascade R-HSA-166166
Vesicle-mediated transport R-HSA-5653656
Platelet activation, signaling and aggregation R-HSA-76002
Toll-like Receptor Cascades R-HSA-168898
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Lysosome Vesicle Biogenesis R-HSA-432720
Immune System R-HSA-168256
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Extracellular matrix organization R-HSA-1474244
Innate Immune System R-HSA-168249
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Amyloid fiber formation R-HSA-977225
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
ECM proteoglycans R-HSA-3000178
Disease R-HSA-1643685
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TRAF6 mediated NF-kB activation R-HSA-933542
G alpha (i) signalling events R-HSA-418594
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
trans-Golgi Network Vesicle Budding R-HSA-199992
GPCR ligand binding R-HSA-500792
Interleukin-1 family signaling R-HSA-446652
Signaling by Interleukins R-HSA-449147
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
The NLRP3 inflammasome R-HSA-844456
Cytokine Signaling in Immune system R-HSA-1280215
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Extracellular matrix organization R-HSA-1474244
Membrane Trafficking R-HSA-199991
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Infectious disease R-HSA-5663205
Signaling by GPCR R-HSA-372790
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Neurodegenerative Diseases R-HSA-8863678
Innate Immune System R-HSA-168249
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Toll-like Receptor Cascades R-HSA-168898
Post-translational protein modification R-HSA-597592
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
ECM proteoglycans R-HSA-3000178
Lysosome Vesicle Biogenesis R-HSA-432720
Platelet activation, signaling and aggregation R-HSA-76002
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523
Platelet degranulation R-HSA-114608
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
GPCR downstream signalling R-HSA-388396
G alpha (q) signalling events R-HSA-416476
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MyD88 dependent cascade initiated on endosome R-HSA-975155
Amyloid fiber formation R-HSA-977225
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Leishmania infection R-HSA-9658195
Disease R-HSA-1643685
Inflammasomes R-HSA-622312
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Post-translational protein phosphorylation R-HSA-8957275
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
G alpha (i) signalling events R-HSA-418594
MyD88 cascade initiated on plasma membrane R-HSA-975871
Protein localization R-HSA-9609507
Immune System R-HSA-168256
Diseases of programmed cell death R-HSA-9645723
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signal Transduction R-HSA-162582
Vesicle-mediated transport R-HSA-5653656
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Hemostasis R-HSA-109582
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Peptide ligand-binding receptors R-HSA-375276
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-1 signaling R-HSA-9020702
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Purinergic signaling in leishmaniasis infection R-HSA-9660826
TRAF6 mediated NF-kB activation R-HSA-933542
Metabolism of proteins R-HSA-392499
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88-independent TLR4 cascade R-HSA-166166
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473
Signaling by Interleukins R-HSA-449147
G alpha (i) signalling events R-HSA-418594
ECM proteoglycans R-HSA-3000178
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Interleukin-1 signaling R-HSA-9020702
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Amyloid fiber formation R-HSA-977225
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Neurodegenerative Diseases R-HSA-8863678
Lysosome Vesicle Biogenesis R-HSA-432720
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
trans-Golgi Network Vesicle Budding R-HSA-199992
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Post-translational protein modification R-HSA-597592
Inflammasomes R-HSA-622312
Signaling by GPCR R-HSA-372790
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Platelet degranulation R-HSA-114608
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Post-translational protein phosphorylation R-HSA-8957275
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Immune System R-HSA-168256
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Vesicle-mediated transport R-HSA-5653656
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Interleukin-1 family signaling R-HSA-446652
Infectious disease R-HSA-5663205
MyD88 cascade initiated on plasma membrane R-HSA-975871
Protein localization R-HSA-9609507
Peptide ligand-binding receptors R-HSA-375276
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Leishmania infection R-HSA-9658195
MyD88-independent TLR4 cascade R-HSA-166166
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
GPCR ligand binding R-HSA-500792
Hemostasis R-HSA-109582
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Disease R-HSA-1643685
TRAF6 mediated NF-kB activation R-HSA-933542
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Innate Immune System R-HSA-168249
The NLRP3 inflammasome R-HSA-844456
Membrane Trafficking R-HSA-199991
Metabolism of proteins R-HSA-392499
Extracellular matrix organization R-HSA-1474244
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of programmed cell death R-HSA-9645723
MyD88 dependent cascade initiated on endosome R-HSA-975155
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Disease R-HSA-1643685
Neurodegenerative Diseases R-HSA-8863678
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by Interleukins R-HSA-449147
Extracellular matrix organization R-HSA-1474244
Amyloid fiber formation R-HSA-977225
Toll-like Receptor Cascades R-HSA-168898
Immune System R-HSA-168256
G alpha (q) signalling events R-HSA-416476
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Membrane Trafficking R-HSA-199991
Leishmania infection R-HSA-9658195
GPCR downstream signalling R-HSA-388396
Interleukin-1 signaling R-HSA-9020702
MyD88 cascade initiated on plasma membrane R-HSA-975871
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Platelet activation, signaling and aggregation R-HSA-76002
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TRAF6 mediated NF-kB activation R-HSA-933542
Signaling by GPCR R-HSA-372790
Interleukin-1 family signaling R-HSA-446652
Platelet degranulation R-HSA-114608
Cytokine Signaling in Immune system R-HSA-1280215
Hemostasis R-HSA-109582
Diseases of programmed cell death R-HSA-9645723
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Peptide ligand-binding receptors R-HSA-375276
Metabolism of proteins R-HSA-392499
GPCR ligand binding R-HSA-500792
Vesicle-mediated transport R-HSA-5653656
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
G alpha (i) signalling events R-HSA-418594
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Purinergic signaling in leishmaniasis infection R-HSA-9660826
ECM proteoglycans R-HSA-3000178
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Innate Immune System R-HSA-168249
Inflammasomes R-HSA-622312
Post-translational protein modification R-HSA-597592
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Protein localization R-HSA-9609507
Infectious disease R-HSA-5663205
trans-Golgi Network Vesicle Budding R-HSA-199992
MyD88-independent TLR4 cascade R-HSA-166166
The NLRP3 inflammasome R-HSA-844456
Post-translational protein phosphorylation R-HSA-8957275
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signal Transduction R-HSA-162582
MyD88 dependent cascade initiated on endosome R-HSA-975155
Lysosome Vesicle Biogenesis R-HSA-432720
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Inflammasomes R-HSA-622312
Leishmania infection R-HSA-9658195
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cytokine Signaling in Immune system R-HSA-1280215
GPCR downstream signalling R-HSA-388396
Neurodegenerative Diseases R-HSA-8863678
Post-translational protein phosphorylation R-HSA-8957275
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Hemostasis R-HSA-109582
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll-like Receptor Cascades R-HSA-168898
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Signaling by GPCR R-HSA-372790
Infectious disease R-HSA-5663205
MyD88 dependent cascade initiated on endosome R-HSA-975155
ECM proteoglycans R-HSA-3000178
Protein localization R-HSA-9609507
Innate Immune System R-HSA-168249
G alpha (i) signalling events R-HSA-418594
Peptide ligand-binding receptors R-HSA-375276
Extracellular matrix organization R-HSA-1474244
Vesicle-mediated transport R-HSA-5653656
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Interleukin-1 signaling R-HSA-9020702
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Immune System R-HSA-168256
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
GPCR ligand binding R-HSA-500792
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Platelet activation, signaling and aggregation R-HSA-76002
Post-translational protein modification R-HSA-597592
MyD88 cascade initiated on plasma membrane R-HSA-975871
G alpha (q) signalling events R-HSA-416476
MyD88-independent TLR4 cascade R-HSA-166166
Advanced glycosylation endproduct receptor signaling R-HSA-879415
The NLRP3 inflammasome R-HSA-844456
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Membrane Trafficking R-HSA-199991
Signaling by Interleukins R-HSA-449147
Interleukin-1 family signaling R-HSA-446652
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
TRAF6 mediated NF-kB activation R-HSA-933542
Metabolism of proteins R-HSA-392499
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473
Lysosome Vesicle Biogenesis R-HSA-432720
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523
trans-Golgi Network Vesicle Budding R-HSA-199992
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Platelet degranulation R-HSA-114608
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Diseases of programmed cell death R-HSA-9645723
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Amyloid fiber formation R-HSA-977225
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Metabolism of proteins R-HSA-392499
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523
Post-translational protein modification R-HSA-597592
Signaling by GPCR R-HSA-372790
Immune System R-HSA-168256
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Protein localization R-HSA-9609507
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473
ECM proteoglycans R-HSA-3000178
Lysosome Vesicle Biogenesis R-HSA-432720
Inflammasomes R-HSA-622312
MyD88 dependent cascade initiated on endosome R-HSA-975155
Extracellular matrix organization R-HSA-1474244
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
G alpha (i) signalling events R-HSA-418594
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Leishmania infection R-HSA-9658195
Disease R-HSA-1643685
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Signal Transduction R-HSA-162582
Hemostasis R-HSA-109582
Innate Immune System R-HSA-168249
Amyloid fiber formation R-HSA-977225
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Infectious disease R-HSA-5663205
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
G alpha (q) signalling events R-HSA-416476
Toll-like Receptor Cascades R-HSA-168898
GPCR ligand binding R-HSA-500792
Membrane Trafficking R-HSA-199991
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Interleukin-1 signaling R-HSA-9020702
Neurodegenerative Diseases R-HSA-8863678
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Vesicle-mediated transport R-HSA-5653656
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
trans-Golgi Network Vesicle Budding R-HSA-199992
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Post-translational protein phosphorylation R-HSA-8957275
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by Interleukins R-HSA-449147
The NLRP3 inflammasome R-HSA-844456
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Diseases of programmed cell death R-HSA-9645723
TRAF6 mediated NF-kB activation R-HSA-933542
Interleukin-1 family signaling R-HSA-446652
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Platelet degranulation R-HSA-114608
Advanced glycosylation endproduct receptor signaling R-HSA-879415
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Platelet activation, signaling and aggregation R-HSA-76002
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Disease R-HSA-1643685
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Interleukin-1 family signaling R-HSA-446652
Neurodegenerative Diseases R-HSA-8863678
Inflammasomes R-HSA-622312
GPCR downstream signalling R-HSA-388396
Amyloid fiber formation R-HSA-977225
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Extracellular matrix organization R-HSA-1474244
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
G alpha (q) signalling events R-HSA-416476
Protein localization R-HSA-9609507
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Platelet degranulation R-HSA-114608
Post-translational protein modification R-HSA-597592
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
GPCR ligand binding R-HSA-500792
MyD88-independent TLR4 cascade R-HSA-166166
Metabolism of proteins R-HSA-392499
TRAF6 mediated NF-kB activation R-HSA-933542
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
G alpha (i) signalling events R-HSA-418594
Leishmania infection R-HSA-9658195
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Interleukins R-HSA-449147
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Immune System R-HSA-168256
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Membrane Trafficking R-HSA-199991
Cytokine Signaling in Immune system R-HSA-1280215
Vesicle-mediated transport R-HSA-5653656
Toll-like Receptor Cascades R-HSA-168898
Peptide ligand-binding receptors R-HSA-375276
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Lysosome Vesicle Biogenesis R-HSA-432720
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523
Diseases of programmed cell death R-HSA-9645723
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Cell recruitment (pro-inflammatory response) R-HSA-9664424
ECM proteoglycans R-HSA-3000178
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Hemostasis R-HSA-109582
Interleukin-1 signaling R-HSA-9020702
Post-translational protein phosphorylation R-HSA-8957275
MyD88 cascade initiated on plasma membrane R-HSA-975871
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
trans-Golgi Network Vesicle Budding R-HSA-199992
The NLRP3 inflammasome R-HSA-844456
Platelet activation, signaling and aggregation R-HSA-76002
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
The NLRP3 inflammasome R-HSA-844456
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Infectious disease R-HSA-5663205
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523
Vesicle-mediated transport R-HSA-5653656
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
GPCR downstream signalling R-HSA-388396
Purinergic signaling in leishmaniasis infection R-HSA-9660826
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Lysosome Vesicle Biogenesis R-HSA-432720
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Membrane Trafficking R-HSA-199991
Amyloid fiber formation R-HSA-977225
Immune System R-HSA-168256
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Cytokine Signaling in Immune system R-HSA-1280215
Inflammasomes R-HSA-622312
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
MyD88 cascade initiated on plasma membrane R-HSA-975871
GPCR ligand binding R-HSA-500792
Leishmania infection R-HSA-9658195
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
Protein localization R-HSA-9609507
Interleukin-1 family signaling R-HSA-446652
Disease R-HSA-1643685
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Peptide ligand-binding receptors R-HSA-375276
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TRAF6 mediated NF-kB activation R-HSA-933542
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Platelet degranulation R-HSA-114608
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Post-translational protein modification R-HSA-597592
ECM proteoglycans R-HSA-3000178
G alpha (q) signalling events R-HSA-416476
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Neurodegenerative Diseases R-HSA-8863678
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Hemostasis R-HSA-109582
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
trans-Golgi Network Vesicle Budding R-HSA-199992
Extracellular matrix organization R-HSA-1474244
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
Diseases of programmed cell death R-HSA-9645723
Post-translational protein phosphorylation R-HSA-8957275
Vesicle-mediated transport R-HSA-5653656
Hemostasis R-HSA-109582
Peptide ligand-binding receptors R-HSA-375276
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Lysosome Vesicle Biogenesis R-HSA-432720
Membrane Trafficking R-HSA-199991
Post-translational protein phosphorylation R-HSA-8957275
Interleukin-1 family signaling R-HSA-446652
Toll-like Receptor Cascades R-HSA-168898
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Innate Immune System R-HSA-168249
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
The NLRP3 inflammasome R-HSA-844456
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523
Inflammasomes R-HSA-622312
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Diseases of programmed cell death R-HSA-9645723
GPCR downstream signalling R-HSA-388396
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Extracellular matrix organization R-HSA-1474244
Advanced glycosylation endproduct receptor signaling R-HSA-879415
G alpha (i) signalling events R-HSA-418594
Amyloid fiber formation R-HSA-977225
MyD88-independent TLR4 cascade R-HSA-166166
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Protein localization R-HSA-9609507
Immune System R-HSA-168256
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Interleukin-1 signaling R-HSA-9020702
Leishmania infection R-HSA-9658195
MyD88 dependent cascade initiated on endosome R-HSA-975155
Neurodegenerative Diseases R-HSA-8863678
Post-translational protein modification R-HSA-597592
MyD88 cascade initiated on plasma membrane R-HSA-975871
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Platelet activation, signaling and aggregation R-HSA-76002
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Platelet degranulation R-HSA-114608
Signaling by GPCR R-HSA-372790
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
trans-Golgi Network Vesicle Budding R-HSA-199992
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
GPCR ligand binding R-HSA-500792
TRAF6 mediated NF-kB activation R-HSA-933542
Disease R-HSA-1643685
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Cytokine Signaling in Immune system R-HSA-1280215
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
G alpha (q) signalling events R-HSA-416476
ECM proteoglycans R-HSA-3000178
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
Extracellular matrix organization R-HSA-1474244
Platelet degranulation R-HSA-114608
Infectious disease R-HSA-5663205
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Post-translational protein phosphorylation R-HSA-8957275
Metabolism of proteins R-HSA-392499
Vesicle-mediated transport R-HSA-5653656
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473
Toll-like Receptor Cascades R-HSA-168898
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Lysosome Vesicle Biogenesis R-HSA-432720
Amyloid fiber formation R-HSA-977225
ECM proteoglycans R-HSA-3000178
Interleukin-1 family signaling R-HSA-446652
TRAF6 mediated NF-kB activation R-HSA-933542
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Interleukin-1 signaling R-HSA-9020702
Neurodegenerative Diseases R-HSA-8863678
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Interleukins R-HSA-449147
G alpha (i) signalling events R-HSA-418594
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Protein localization R-HSA-9609507
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Membrane Trafficking R-HSA-199991
MyD88 dependent cascade initiated on endosome R-HSA-975155
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Inflammasomes R-HSA-622312
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
The NLRP3 inflammasome R-HSA-844456
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
GPCR ligand binding R-HSA-500792
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
Leishmania infection R-HSA-9658195
Diseases of programmed cell death R-HSA-9645723
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Purinergic signaling in leishmaniasis infection R-HSA-9660826
GPCR downstream signalling R-HSA-388396
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Hemostasis R-HSA-109582
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
trans-Golgi Network Vesicle Budding R-HSA-199992
MyD88-independent TLR4 cascade R-HSA-166166
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523
Post-translational protein modification R-HSA-597592
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Immune System R-HSA-168256
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
trans-Golgi Network Vesicle Budding R-HSA-199992
Metabolism of proteins R-HSA-392499
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Purinergic signaling in leishmaniasis infection R-HSA-9660826
G alpha (q) signalling events R-HSA-416476
Interleukin-1 signaling R-HSA-9020702
Lysosome Vesicle Biogenesis R-HSA-432720
Platelet degranulation R-HSA-114608
Protein localization R-HSA-9609507
Disease R-HSA-1643685
Platelet activation, signaling and aggregation R-HSA-76002
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cytokine Signaling in Immune system R-HSA-1280215
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
GPCR downstream signalling R-HSA-388396
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by Interleukins R-HSA-449147
Vesicle-mediated transport R-HSA-5653656
Amyloid fiber formation R-HSA-977225
Innate Immune System R-HSA-168249
MyD88-independent TLR4 cascade R-HSA-166166
Neurodegenerative Diseases R-HSA-8863678
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Leishmania infection R-HSA-9658195
Signaling by GPCR R-HSA-372790
ECM proteoglycans R-HSA-3000178
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll-like Receptor Cascades R-HSA-168898
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Membrane Trafficking R-HSA-199991
The NLRP3 inflammasome R-HSA-844456
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Interleukin-1 family signaling R-HSA-446652
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Inflammasomes R-HSA-622312
TRAF6 mediated NF-kB activation R-HSA-933542
Post-translational protein phosphorylation R-HSA-8957275
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Extracellular matrix organization R-HSA-1474244
Hemostasis R-HSA-109582
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Diseases of programmed cell death R-HSA-9645723

Expression Atlas ENSG00000142192
NCBI gene (formerly Entrezgene) 351
GeneCards 620
HGNC Symbol HGNC:620
MIM gene 104760
MIM morbid 605714
UniProtKB Gene Name P05067
WikiGene 351
Gene: PSMB10
Ensembl ID : ENSG00000205220
Description: proteasome 20S subunit beta 10
Gene Synonyms: BETA2I,LMP10,MECL1,MGC1665
6 APIs:
172 Possible Orthologues:

CLEC7A (Dectin-1) signaling R-HSA-5607764
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
M Phase R-HSA-68886
Gene expression (Transcription) R-HSA-74160
S Phase R-HSA-69242
Adaptive Immune System R-HSA-1280218
Regulation of mitotic cell cycle R-HSA-453276
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle R-HSA-1640170
Neddylation R-HSA-8951664
Signaling by Hedgehog R-HSA-5358351
Orc1 removal from chromatin R-HSA-68949
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular response to hypoxia R-HSA-1234174
Disorders of transmembrane transporters R-HSA-5619115
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cytokine Signaling in Immune system R-HSA-1280215
Nuclear events mediated by NFE2L2 R-HSA-9759194
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of proteins R-HSA-392499
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by WNT R-HSA-195721
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Innate Immune System R-HSA-168249
Nervous system development R-HSA-9675108
Cellular responses to stimuli R-HSA-8953897
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Synthesis of DNA R-HSA-69239
Deubiquitination R-HSA-5688426
Generic Transcription Pathway R-HSA-212436
Switching of origins to a post-replicative state R-HSA-69052
Cellular responses to stress R-HSA-2262752
Degradation of DVL R-HSA-4641258
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Infectious disease R-HSA-5663205
Interleukin-1 signaling R-HSA-9020702
Degradation of AXIN R-HSA-4641257
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Vpu mediated degradation of CD4 R-HSA-180534
Cellular response to chemical stress R-HSA-9711123
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Checkpoints R-HSA-69481
G1/S DNA Damage Checkpoints R-HSA-69615
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Axon guidance R-HSA-422475
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK1/MAPK3 signaling R-HSA-5684996
RNA Polymerase II Transcription R-HSA-73857
Mitotic G1 phase and G1/S transition R-HSA-453279
PCP/CE pathway R-HSA-4086400
Mitotic G2-G2/M phases R-HSA-453274
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle Checkpoints R-HSA-69620
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH R-HSA-157118
Disease R-HSA-1643685
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of Apoptosis R-HSA-169911
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX1 R-HSA-8878171
Downstream TCR signaling R-HSA-202424
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Beta-catenin independent WNT signaling R-HSA-3858494
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX2 expression and activity R-HSA-8939902
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants are degraded by ERAD R-HSA-5362768
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
Metabolism of polyamines R-HSA-351202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK family signaling cascades R-HSA-5683057
Degradation of beta-catenin by the destruction complex R-HSA-195253
PTEN Regulation R-HSA-6807070
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'off' state R-HSA-5610787
Regulation of RAS by GAPs R-HSA-5658442
Developmental Biology R-HSA-1266738
Regulation of PTEN stability and activity R-HSA-8948751
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by ROBO receptors R-HSA-376176
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI1 by the proteasome R-HSA-5610780
CLEC7A (Dectin-1) signaling R-HSA-5607764
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing-Cross presentation R-HSA-1236975
Hh mutants abrogate ligand secretion R-HSA-5387390
DNA Replication Pre-Initiation R-HSA-69002
Host Interactions of HIV factors R-HSA-162909
KEAP1-NFE2L2 pathway R-HSA-9755511
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Interleukins R-HSA-449147
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of GLI2 by the proteasome R-HSA-5610783
Apoptosis R-HSA-109581
Mitotic Anaphase R-HSA-68882
UCH proteinases R-HSA-5689603
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX2 R-HSA-8878166
TCF dependent signaling in response to WNT R-HSA-201681
Immune System R-HSA-168256
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle, Mitotic R-HSA-69278
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX3 R-HSA-8878159
RAF/MAP kinase cascade R-HSA-5673001
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
ABC-family proteins mediated transport R-HSA-382556
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
ABC transporter disorders R-HSA-5619084
HIV Infection R-HSA-162906
Assembly of the pre-replicative complex R-HSA-68867
DNA Replication R-HSA-69306
Interleukin-1 family signaling R-HSA-446652
G2/M Transition R-HSA-69275
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G1/S Transition R-HSA-69206
Metabolism of RNA R-HSA-8953854
Hedgehog 'on' state R-HSA-5632684
TCR signaling R-HSA-202403
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism R-HSA-1430728
Post-translational protein modification R-HSA-597592
Programmed Cell Death R-HSA-5357801
Stabilization of p53 R-HSA-69541
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Transport of small molecules R-HSA-382551
Cellular response to hypoxia R-HSA-1234174
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G2/M Transition R-HSA-69275
Axon guidance R-HSA-422475
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic Anaphase R-HSA-68882
TCF dependent signaling in response to WNT R-HSA-201681
Defective CFTR causes cystic fibrosis R-HSA-5678895
Interleukin-1 family signaling R-HSA-446652
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Independent DNA Damage Response R-HSA-69610
Mitotic G1 phase and G1/S transition R-HSA-453279
M Phase R-HSA-68886
Signaling by Interleukins R-HSA-449147
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
UCH proteinases R-HSA-5689603
TCR signaling R-HSA-202403
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH R-HSA-157118
MAPK1/MAPK3 signaling R-HSA-5684996
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Stabilization of p53 R-HSA-69541
Switching of origins to a post-replicative state R-HSA-69052
Deubiquitination R-HSA-5688426
Transport of small molecules R-HSA-382551
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
FCERI mediated NF-kB activation R-HSA-2871837
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disorders of transmembrane transporters R-HSA-5619115
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants are degraded by ERAD R-HSA-5362768
Programmed Cell Death R-HSA-5357801
Apoptosis R-HSA-109581
Gene expression (Transcription) R-HSA-74160
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hh mutants abrogate ligand secretion R-HSA-5387390
Adaptive Immune System R-HSA-1280218
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
Nervous system development R-HSA-9675108
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of GLI2 by the proteasome R-HSA-5610783
Synthesis of DNA R-HSA-69239
Hedgehog ligand biogenesis R-HSA-5358346
Hedgehog 'on' state R-HSA-5632684
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
RNA Polymerase II Transcription R-HSA-73857
C-type lectin receptors (CLRs) R-HSA-5621481
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ub-specific processing proteases R-HSA-5689880
Metabolism of RNA R-HSA-8953854
Degradation of DVL R-HSA-4641258
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Separation of Sister Chromatids R-HSA-2467813
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle, Mitotic R-HSA-69278
Cytokine Signaling in Immune system R-HSA-1280215
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PTEN Regulation R-HSA-6807070
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Orc1 removal from chromatin R-HSA-68949
Cellular response to chemical stress R-HSA-9711123
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism R-HSA-1430728
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RAS by GAPs R-HSA-5658442
Activation of NF-kappaB in B cells R-HSA-1169091
KEAP1-NFE2L2 pathway R-HSA-9755511
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S DNA Damage Checkpoints R-HSA-69615
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Innate Immune System R-HSA-168249
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of AXIN R-HSA-4641257
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Neddylation R-HSA-8951664
Cell Cycle Checkpoints R-HSA-69620
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
DNA Replication Pre-Initiation R-HSA-69002
PIP3 activates AKT signaling R-HSA-1257604
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX1 R-HSA-8878171
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stress R-HSA-2262752
Assembly of the pre-replicative complex R-HSA-68867
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Generic Transcription Pathway R-HSA-212436
Regulation of PTEN stability and activity R-HSA-8948751
ER-Phagosome pathway R-HSA-1236974
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle R-HSA-1640170
Metabolism of proteins R-HSA-392499
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G2/M Checkpoints R-HSA-69481
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stimuli R-HSA-8953897
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing-Cross presentation R-HSA-1236975
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
MAPK family signaling cascades R-HSA-5683057
Regulation of RUNX2 expression and activity R-HSA-8939902
PCP/CE pathway R-HSA-4086400
Downstream TCR signaling R-HSA-202424
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Developmental Biology R-HSA-1266738
Signaling by Hedgehog R-HSA-5358351
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI1 by the proteasome R-HSA-5610780
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX2 R-HSA-8878166
Host Interactions of HIV factors R-HSA-162909
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Replication R-HSA-69306
G1/S Transition R-HSA-69206
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of polyamines R-HSA-351202
Vpu mediated degradation of CD4 R-HSA-180534
HIV Infection R-HSA-162906
Regulation of RUNX3 expression and activity R-HSA-8941858
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by NOTCH4 R-HSA-9013694
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Post-translational protein modification R-HSA-597592
Signaling by ROBO receptors R-HSA-376176
M Phase R-HSA-68886
DNA Replication Pre-Initiation R-HSA-69002
Stabilization of p53 R-HSA-69541
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of AXIN R-HSA-4641257
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1 DNA Damage Response R-HSA-69563
PIP3 activates AKT signaling R-HSA-1257604
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
Adaptive Immune System R-HSA-1280218
Separation of Sister Chromatids R-HSA-2467813
Regulation of PTEN stability and activity R-HSA-8948751
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
HIV Infection R-HSA-162906
Antigen processing-Cross presentation R-HSA-1236975
MAPK6/MAPK4 signaling R-HSA-5687128
Neddylation R-HSA-8951664
Nervous system development R-HSA-9675108
Orc1 removal from chromatin R-HSA-68949
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Nuclear events mediated by NFE2L2 R-HSA-9759194
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Mitotic Anaphase R-HSA-68882
Immune System R-HSA-168256
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of RUNX3 expression and activity R-HSA-8941858
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Hedgehog R-HSA-5358351
Hh mutants abrogate ligand secretion R-HSA-5387390
FCERI mediated NF-kB activation R-HSA-2871837
Interleukin-1 family signaling R-HSA-446652
Vif-mediated degradation of APOBEC3G R-HSA-180585
Synthesis of DNA R-HSA-69239
ABC transporter disorders R-HSA-5619084
Programmed Cell Death R-HSA-5357801
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
PCP/CE pathway R-HSA-4086400
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
G2/M Transition R-HSA-69275
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Metaphase and Anaphase R-HSA-2555396
TCR signaling R-HSA-202403
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Disease R-HSA-1643685
Signaling by WNT R-HSA-195721
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants are degraded by ERAD R-HSA-5362768
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Innate Immune System R-HSA-168249
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Interleukin-1 signaling R-HSA-9020702
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular response to chemical stress R-HSA-9711123
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
ER-Phagosome pathway R-HSA-1236974
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of Apoptosis R-HSA-169911
Metabolism of RNA R-HSA-8953854
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Post-translational protein modification R-HSA-597592
Intracellular signaling by second messengers R-HSA-9006925
RNA Polymerase II Transcription R-HSA-73857
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX1 R-HSA-8878171
Hedgehog 'on' state R-HSA-5632684
DNA Replication R-HSA-69306
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
S Phase R-HSA-69242
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RAF/MAP kinase cascade R-HSA-5673001
Switching of origins to a post-replicative state R-HSA-69052
Cyclin E associated events during G1/S transition R-HSA-69202
UCH proteinases R-HSA-5689603
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Negative regulation of NOTCH4 signaling R-HSA-9604323
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
Infectious disease R-HSA-5663205
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G2/M Checkpoints R-HSA-69481
Generic Transcription Pathway R-HSA-212436
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Independent DNA Damage Response R-HSA-69610
Downstream TCR signaling R-HSA-202424
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by NOTCH R-HSA-157118
Assembly of the pre-replicative complex R-HSA-68867
Gene expression (Transcription) R-HSA-74160
ABC-family proteins mediated transport R-HSA-382556
Host Interactions of HIV factors R-HSA-162909
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX3 R-HSA-8878159
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Beta-catenin independent WNT signaling R-HSA-3858494
Deubiquitination R-HSA-5688426
Metabolism R-HSA-1430728
G1/S Transition R-HSA-69206
Metabolism of amino acids and derivatives R-HSA-71291
MAPK1/MAPK3 signaling R-HSA-5684996
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK family signaling cascades R-HSA-5683057
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular response to hypoxia R-HSA-1234174
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stress R-HSA-2262752
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ub-specific processing proteases R-HSA-5689880
Transport of small molecules R-HSA-382551
Regulation of mitotic cell cycle R-HSA-453276
Regulation of RAS by GAPs R-HSA-5658442
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Assembly of the pre-replicative complex R-HSA-68867
Synthesis of DNA R-HSA-69239
Programmed Cell Death R-HSA-5357801
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 family signaling R-HSA-446652
Transport of small molecules R-HSA-382551
Hedgehog ligand biogenesis R-HSA-5358346
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing-Cross presentation R-HSA-1236975
Degradation of GLI1 by the proteasome R-HSA-5610780
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Transition R-HSA-69275
Host Interactions of HIV factors R-HSA-162909
Separation of Sister Chromatids R-HSA-2467813
Degradation of DVL R-HSA-4641258
HIV Infection R-HSA-162906
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Developmental Biology R-HSA-1266738
Degradation of beta-catenin by the destruction complex R-HSA-195253
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stimuli R-HSA-8953897
Signaling by Hedgehog R-HSA-5358351
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Post-translational protein modification R-HSA-597592
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mitotic cell cycle R-HSA-453276
Orc1 removal from chromatin R-HSA-68949
M Phase R-HSA-68886
ER-Phagosome pathway R-HSA-1236974
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cyclin E associated events during G1/S transition R-HSA-69202
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by ROBO receptors R-HSA-376176
MAPK family signaling cascades R-HSA-5683057
G1/S Transition R-HSA-69206
Activation of NF-kappaB in B cells R-HSA-1169091
G1/S DNA Damage Checkpoints R-HSA-69615
CLEC7A (Dectin-1) signaling R-HSA-5607764
Asymmetric localization of PCP proteins R-HSA-4608870
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of RAS by GAPs R-HSA-5658442
Generic Transcription Pathway R-HSA-212436
Signaling by WNT R-HSA-195721
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Intracellular signaling by second messengers R-HSA-9006925
Deubiquitination R-HSA-5688426
Degradation of AXIN R-HSA-4641257
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of proteins R-HSA-392499
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vpu mediated degradation of CD4 R-HSA-180534
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PCP/CE pathway R-HSA-4086400
Mitotic Anaphase R-HSA-68882
Apoptosis R-HSA-109581
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Disease R-HSA-1643685
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle R-HSA-1640170
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Stabilization of p53 R-HSA-69541
PTEN Regulation R-HSA-6807070
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
FCERI mediated NF-kB activation R-HSA-2871837
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular response to chemical stress R-HSA-9711123
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of Apoptosis R-HSA-169911
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G2/M Checkpoints R-HSA-69481
Mitotic G1 phase and G1/S transition R-HSA-453279
Interleukin-1 signaling R-HSA-9020702
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Adaptive Immune System R-HSA-1280218
C-type lectin receptors (CLRs) R-HSA-5621481
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
DNA Replication R-HSA-69306
Cellular response to hypoxia R-HSA-1234174
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Gene expression (Transcription) R-HSA-74160
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by NOTCH R-HSA-157118
UCH proteinases R-HSA-5689603
Beta-catenin independent WNT signaling R-HSA-3858494
Infectious disease R-HSA-5663205
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle Checkpoints R-HSA-69620
p53-Independent DNA Damage Response R-HSA-69610
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hedgehog 'off' state R-HSA-5610787
Downstream TCR signaling R-HSA-202424
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism R-HSA-1430728
Ub-specific processing proteases R-HSA-5689880
ABC transporter disorders R-HSA-5619084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX3 R-HSA-8878159
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK1/MAPK3 signaling R-HSA-5684996
Hedgehog 'on' state R-HSA-5632684
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of PTEN stability and activity R-HSA-8948751
Transcriptional regulation by RUNX1 R-HSA-8878171
Switching of origins to a post-replicative state R-HSA-69052
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of polyamines R-HSA-351202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signal Transduction R-HSA-162582
Signaling by NOTCH4 R-HSA-9013694
TCR signaling R-HSA-202403
Cellular responses to stress R-HSA-2262752
Metabolism of RNA R-HSA-8953854
Nuclear events mediated by NFE2L2 R-HSA-9759194
Axon guidance R-HSA-422475
Metabolism of amino acids and derivatives R-HSA-71291
Innate Immune System R-HSA-168249
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of proteins R-HSA-392499
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
S Phase R-HSA-69242
Gene expression (Transcription) R-HSA-74160
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'on' state R-HSA-5632684
Infectious disease R-HSA-5663205
DNA Replication Pre-Initiation R-HSA-69002
RNA Polymerase II Transcription R-HSA-73857
Orc1 removal from chromatin R-HSA-68949
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cyclin E associated events during G1/S transition R-HSA-69202
Axon guidance R-HSA-422475
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transport of small molecules R-HSA-382551
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular response to hypoxia R-HSA-1234174
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vpu mediated degradation of CD4 R-HSA-180534
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of RNA R-HSA-8953854
G2/M Checkpoints R-HSA-69481
Metabolism of polyamines R-HSA-351202
Antigen processing-Cross presentation R-HSA-1236975
Cytokine Signaling in Immune system R-HSA-1280215
Cell Cycle, Mitotic R-HSA-69278
Signaling by Hedgehog R-HSA-5358351
Mitotic G1 phase and G1/S transition R-HSA-453279
Neddylation R-HSA-8951664
TCR signaling R-HSA-202403
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 family signaling R-HSA-446652
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of DVL R-HSA-4641258
Stabilization of p53 R-HSA-69541
Disease R-HSA-1643685
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Switching of origins to a post-replicative state R-HSA-69052
Defective CFTR causes cystic fibrosis R-HSA-5678895
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hh mutants are degraded by ERAD R-HSA-5362768
Immune System R-HSA-168256
TCF dependent signaling in response to WNT R-HSA-201681
Hh mutants abrogate ligand secretion R-HSA-5387390
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
Signaling by NOTCH4 R-HSA-9013694
Activation of NF-kappaB in B cells R-HSA-1169091
Assembly of the pre-replicative complex R-HSA-68867
Apoptosis R-HSA-109581
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mitotic cell cycle R-HSA-453276
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular responses to stimuli R-HSA-8953897
G1/S DNA Damage Checkpoints R-HSA-69615
KEAP1-NFE2L2 pathway R-HSA-9755511
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Independent DNA Damage Response R-HSA-69610
Regulation of Apoptosis R-HSA-169911
Mitotic Metaphase and Anaphase R-HSA-2555396
Nuclear events mediated by NFE2L2 R-HSA-9759194
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC transporter disorders R-HSA-5619084
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Intracellular signaling by second messengers R-HSA-9006925
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by NOTCH R-HSA-157118
ABC-family proteins mediated transport R-HSA-382556
Adaptive Immune System R-HSA-1280218
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1/S Transition R-HSA-69206
Host Interactions of HIV factors R-HSA-162909
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX1 R-HSA-8878171
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of beta-catenin by the destruction complex R-HSA-195253
PCP/CE pathway R-HSA-4086400
Downstream TCR signaling R-HSA-202424
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
PIP3 activates AKT signaling R-HSA-1257604
M Phase R-HSA-68886
Synthesis of DNA R-HSA-69239
Regulation of RAS by GAPs R-HSA-5658442
Cellular response to chemical stress R-HSA-9711123
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK family signaling cascades R-HSA-5683057
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of GLI1 by the proteasome R-HSA-5610780
Vif-mediated degradation of APOBEC3G R-HSA-180585
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
RAF/MAP kinase cascade R-HSA-5673001
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of AXIN R-HSA-4641257
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by WNT R-HSA-195721
Hedgehog 'off' state R-HSA-5610787
Ub-specific processing proteases R-HSA-5689880
Nervous system development R-HSA-9675108
Hedgehog ligand biogenesis R-HSA-5358346
Beta-catenin independent WNT signaling R-HSA-3858494
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
UCH proteinases R-HSA-5689603
DNA Replication R-HSA-69306
Disorders of transmembrane transporters R-HSA-5619115
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism R-HSA-1430728
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
Regulation of PTEN stability and activity R-HSA-8948751
Deubiquitination R-HSA-5688426
Cell Cycle R-HSA-1640170
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic Anaphase R-HSA-68882
Interleukin-1 signaling R-HSA-9020702
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle Checkpoints R-HSA-69620
Vpu mediated degradation of CD4 R-HSA-180534
Activation of NF-kappaB in B cells R-HSA-1169091
ABC transporter disorders R-HSA-5619084
TCR signaling R-HSA-202403
Separation of Sister Chromatids R-HSA-2467813
Defective CFTR causes cystic fibrosis R-HSA-5678895
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by the B Cell Receptor (BCR) R-HSA-983705
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1 DNA Damage Response R-HSA-69563
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Axon guidance R-HSA-422475
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
G1/S Transition R-HSA-69206
Innate Immune System R-HSA-168249
Interleukin-1 family signaling R-HSA-446652
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Apoptosis R-HSA-109581
Cyclin E associated events during G1/S transition R-HSA-69202
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Interleukin-1 signaling R-HSA-9020702
Disorders of transmembrane transporters R-HSA-5619115
M Phase R-HSA-68886
Degradation of GLI1 by the proteasome R-HSA-5610780
DNA Replication R-HSA-69306
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RAS by GAPs R-HSA-5658442
Regulation of mitotic cell cycle R-HSA-453276
Metabolism R-HSA-1430728
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by WNT R-HSA-195721
HIV Infection R-HSA-162906
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
G2/M Transition R-HSA-69275
Regulation of Apoptosis R-HSA-169911
Signaling by NOTCH R-HSA-157118
Cellular responses to stress R-HSA-2262752
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Negative regulation of NOTCH4 signaling R-HSA-9604323
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ABC-family proteins mediated transport R-HSA-382556
Signaling by ROBO receptors R-HSA-376176
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing-Cross presentation R-HSA-1236975
FCERI mediated NF-kB activation R-HSA-2871837
Hedgehog 'off' state R-HSA-5610787
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
ER-Phagosome pathway R-HSA-1236974
Cell Cycle, Mitotic R-HSA-69278
Degradation of DVL R-HSA-4641258
Mitotic G2-G2/M phases R-HSA-453274
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cellular responses to stimuli R-HSA-8953897
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
Orc1 removal from chromatin R-HSA-68949
Deubiquitination R-HSA-5688426
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX2 R-HSA-8878166
Infectious disease R-HSA-5663205
Synthesis of DNA R-HSA-69239
Degradation of GLI2 by the proteasome R-HSA-5610783
Transcriptional regulation by RUNX3 R-HSA-8878159
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of proteins R-HSA-392499
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Neddylation R-HSA-8951664
Gene expression (Transcription) R-HSA-74160
CLEC7A (Dectin-1) signaling R-HSA-5607764
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
C-type lectin receptors (CLRs) R-HSA-5621481
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular response to hypoxia R-HSA-1234174
Signaling by Hedgehog R-HSA-5358351
Post-translational protein modification R-HSA-597592
Stabilization of p53 R-HSA-69541
Signaling by NOTCH4 R-HSA-9013694
G2/M Checkpoints R-HSA-69481
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'on' state R-HSA-5632684
MAPK1/MAPK3 signaling R-HSA-5684996
Transport of small molecules R-HSA-382551
Nuclear events mediated by NFE2L2 R-HSA-9759194
Programmed Cell Death R-HSA-5357801
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Assembly of the pre-replicative complex R-HSA-68867
S Phase R-HSA-69242
Degradation of AXIN R-HSA-4641257
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic Anaphase R-HSA-68882
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Nervous system development R-HSA-9675108
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of RNA R-HSA-8953854
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Class I MHC mediated antigen processing & presentation R-HSA-983169
Downstream TCR signaling R-HSA-202424
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX1 R-HSA-8878171
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Generic Transcription Pathway R-HSA-212436
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
MAPK6/MAPK4 signaling R-HSA-5687128
Ub-specific processing proteases R-HSA-5689880
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
Mitotic G1 phase and G1/S transition R-HSA-453279
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle Checkpoints R-HSA-69620
Switching of origins to a post-replicative state R-HSA-69052
Disease R-HSA-1643685
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PIP3 activates AKT signaling R-HSA-1257604
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of polyamines R-HSA-351202
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Nervous system development R-HSA-9675108
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cellular response to hypoxia R-HSA-1234174
Metabolism R-HSA-1430728
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH R-HSA-157118
Degradation of DVL R-HSA-4641258
Axon guidance R-HSA-422475
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing-Cross presentation R-HSA-1236975
Separation of Sister Chromatids R-HSA-2467813
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Synthesis of DNA R-HSA-69239
Degradation of AXIN R-HSA-4641257
ABC-family proteins mediated transport R-HSA-382556
G1/S DNA Damage Checkpoints R-HSA-69615
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
Downstream TCR signaling R-HSA-202424
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stimuli R-HSA-8953897
Hh mutants are degraded by ERAD R-HSA-5362768
RAF/MAP kinase cascade R-HSA-5673001
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle R-HSA-1640170
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Interleukin-1 signaling R-HSA-9020702
Degradation of GLI2 by the proteasome R-HSA-5610783
Activation of NF-kappaB in B cells R-HSA-1169091
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism of proteins R-HSA-392499
Vpu mediated degradation of CD4 R-HSA-180534
Innate Immune System R-HSA-168249
Ub-specific processing proteases R-HSA-5689880
Metabolism of amino acids and derivatives R-HSA-71291
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cell Cycle, Mitotic R-HSA-69278
Signaling by WNT R-HSA-195721
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PTEN Regulation R-HSA-6807070
DNA Replication R-HSA-69306
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Assembly of the pre-replicative complex R-HSA-68867
Hedgehog 'off' state R-HSA-5610787
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
Deubiquitination R-HSA-5688426
Cell Cycle Checkpoints R-HSA-69620
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G2/M Checkpoints R-HSA-69481
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of Apoptosis R-HSA-169911
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of polyamines R-HSA-351202
ER-Phagosome pathway R-HSA-1236974
Beta-catenin independent WNT signaling R-HSA-3858494
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to chemical stress R-HSA-9711123
Regulation of RUNX2 expression and activity R-HSA-8939902
FCERI mediated NF-kB activation R-HSA-2871837
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by ROBO receptors R-HSA-376176
Class I MHC mediated antigen processing & presentation R-HSA-983169
RNA Polymerase II Transcription R-HSA-73857
Stabilization of p53 R-HSA-69541
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Disease R-HSA-1643685
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic G1 phase and G1/S transition R-HSA-453279
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by NOTCH4 R-HSA-9013694
Cyclin E associated events during G1/S transition R-HSA-69202
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of RNA R-HSA-8953854
UCH proteinases R-HSA-5689603
Orc1 removal from chromatin R-HSA-68949
Infectious disease R-HSA-5663205
G1/S Transition R-HSA-69206
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Host Interactions of HIV factors R-HSA-162909
Degradation of beta-catenin by the destruction complex R-HSA-195253
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
S Phase R-HSA-69242
Cytokine Signaling in Immune system R-HSA-1280215
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Post-translational protein modification R-HSA-597592
G2/M Transition R-HSA-69275
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
TCR signaling R-HSA-202403
Transport of small molecules R-HSA-382551
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Interleukins R-HSA-449147
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of GLI1 by the proteasome R-HSA-5610780
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Anaphase R-HSA-68882
Hedgehog 'on' state R-HSA-5632684
HIV Infection R-HSA-162906
Switching of origins to a post-replicative state R-HSA-69052
Vif-mediated degradation of APOBEC3G R-HSA-180585
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mitotic cell cycle R-HSA-453276
Immune System R-HSA-168256
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hedgehog ligand biogenesis R-HSA-5358346
Intracellular signaling by second messengers R-HSA-9006925
Developmental Biology R-HSA-1266738
DNA Replication Pre-Initiation R-HSA-69002
Apoptosis R-HSA-109581
p53-Independent DNA Damage Response R-HSA-69610
C-type lectin receptors (CLRs) R-HSA-5621481
Cyclin E associated events during G1/S transition R-HSA-69202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
Cell Cycle Checkpoints R-HSA-69620
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Interleukin-1 signaling R-HSA-9020702
MAPK family signaling cascades R-HSA-5683057
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX3 R-HSA-8878159
Ub-specific processing proteases R-HSA-5689880
Hedgehog 'on' state R-HSA-5632684
Innate Immune System R-HSA-168249
Hedgehog 'off' state R-HSA-5610787
Regulation of RUNX2 expression and activity R-HSA-8939902
Intracellular signaling by second messengers R-HSA-9006925
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vpu mediated degradation of CD4 R-HSA-180534
Signal Transduction R-HSA-162582
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
Signaling by ROBO receptors R-HSA-376176
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of proteins R-HSA-392499
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Developmental Biology R-HSA-1266738
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
UCH proteinases R-HSA-5689603
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream TCR signaling R-HSA-202424
Signaling by Hedgehog R-HSA-5358351
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH4 R-HSA-9013694
Adaptive Immune System R-HSA-1280218
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH R-HSA-157118
PCP/CE pathway R-HSA-4086400
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of DVL R-HSA-4641258
Cellular response to chemical stress R-HSA-9711123
G1/S Transition R-HSA-69206
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Defective CFTR causes cystic fibrosis R-HSA-5678895
Axon guidance R-HSA-422475
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Independent DNA Damage Response R-HSA-69610
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of Apoptosis R-HSA-169911
Vif-mediated degradation of APOBEC3G R-HSA-180585
Disease R-HSA-1643685
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RNA Polymerase II Transcription R-HSA-73857
Synthesis of DNA R-HSA-69239
ER-Phagosome pathway R-HSA-1236974
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic G1 phase and G1/S transition R-HSA-453279
RAF/MAP kinase cascade R-HSA-5673001
Degradation of beta-catenin by the destruction complex R-HSA-195253
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G2/M Checkpoints R-HSA-69481
ABC transporter disorders R-HSA-5619084
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transport of small molecules R-HSA-382551
HIV Infection R-HSA-162906
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Metabolism R-HSA-1430728
Regulation of mitotic cell cycle R-HSA-453276
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by WNT R-HSA-195721
Neddylation R-HSA-8951664
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle, Mitotic R-HSA-69278
Metabolism of polyamines R-HSA-351202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
PIP3 activates AKT signaling R-HSA-1257604
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
DNA Replication Pre-Initiation R-HSA-69002
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 family signaling R-HSA-446652
Separation of Sister Chromatids R-HSA-2467813
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Antigen processing-Cross presentation R-HSA-1236975
Gene expression (Transcription) R-HSA-74160
Hh mutants are degraded by ERAD R-HSA-5362768
Stabilization of p53 R-HSA-69541
Cellular responses to stimuli R-HSA-8953897
Regulation of PTEN stability and activity R-HSA-8948751
Generic Transcription Pathway R-HSA-212436
Orc1 removal from chromatin R-HSA-68949
TCR signaling R-HSA-202403
Degradation of AXIN R-HSA-4641257
Mitotic Anaphase R-HSA-68882
DNA Replication R-HSA-69306
Programmed Cell Death R-HSA-5357801
Metabolism of amino acids and derivatives R-HSA-71291
Cellular responses to stress R-HSA-2262752
Cell Cycle R-HSA-1640170
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCF dependent signaling in response to WNT R-HSA-201681
Assembly of the pre-replicative complex R-HSA-68867
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of RAS by GAPs R-HSA-5658442
PTEN Regulation R-HSA-6807070
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
Cytokine Signaling in Immune system R-HSA-1280215
Apoptosis R-HSA-109581
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nervous system development R-HSA-9675108
Disorders of transmembrane transporters R-HSA-5619115
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
FCERI mediated NF-kB activation R-HSA-2871837
Metabolism of RNA R-HSA-8953854
Signaling by Interleukins R-HSA-449147
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Programmed Cell Death R-HSA-5357801
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by the B Cell Receptor (BCR) R-HSA-983705
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Post-translational protein modification R-HSA-597592
Cellular responses to stimuli R-HSA-8953897
Separation of Sister Chromatids R-HSA-2467813
M Phase R-HSA-68886
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Downstream TCR signaling R-HSA-202424
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants are degraded by ERAD R-HSA-5362768
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Interleukin-1 family signaling R-HSA-446652
Cell Cycle R-HSA-1640170
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of beta-catenin by the destruction complex R-HSA-195253
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by ROBO receptors R-HSA-376176
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cyclin E associated events during G1/S transition R-HSA-69202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular response to chemical stress R-HSA-9711123
G1/S Transition R-HSA-69206
Disease R-HSA-1643685
Neddylation R-HSA-8951664
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Stabilization of p53 R-HSA-69541
UCH proteinases R-HSA-5689603
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Developmental Biology R-HSA-1266738
FCERI mediated NF-kB activation R-HSA-2871837
Vpu mediated degradation of CD4 R-HSA-180534
S Phase R-HSA-69242
Transport of small molecules R-HSA-382551
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Independent DNA Damage Response R-HSA-69610
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of proteins R-HSA-392499
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Nervous system development R-HSA-9675108
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Regulation of mitotic cell cycle R-HSA-453276
ABC-family proteins mediated transport R-HSA-382556
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX1 R-HSA-8878171
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Checkpoints R-HSA-69481
PCP/CE pathway R-HSA-4086400
Signaling by Interleukins R-HSA-449147
Metabolism of RNA R-HSA-8953854
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH4 R-HSA-9013694
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle Checkpoints R-HSA-69620
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
PIP3 activates AKT signaling R-HSA-1257604
Degradation of DVL R-HSA-4641258
TCR signaling R-HSA-202403
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Metabolism of polyamines R-HSA-351202
Activation of NF-kappaB in B cells R-HSA-1169091
G2/M Transition R-HSA-69275
Ub-specific processing proteases R-HSA-5689880
Switching of origins to a post-replicative state R-HSA-69052
Regulation of RUNX3 expression and activity R-HSA-8941858
Synthesis of DNA R-HSA-69239
Host Interactions of HIV factors R-HSA-162909
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Hedgehog R-HSA-5358351
Signal Transduction R-HSA-162582
Mitotic Anaphase R-HSA-68882
Beta-catenin independent WNT signaling R-HSA-3858494
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism R-HSA-1430728
ABC transporter disorders R-HSA-5619084
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G2-G2/M phases R-HSA-453274
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RAS by GAPs R-HSA-5658442
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hedgehog 'off' state R-HSA-5610787
Axon guidance R-HSA-422475
Signaling by NOTCH R-HSA-157118
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of AXIN R-HSA-4641257
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Generic Transcription Pathway R-HSA-212436
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX3 R-HSA-8878159
Adaptive Immune System R-HSA-1280218
Cytokine Signaling in Immune system R-HSA-1280215
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hedgehog 'on' state R-HSA-5632684
Mitotic Metaphase and Anaphase R-HSA-2555396
ER-Phagosome pathway R-HSA-1236974
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI2 by the proteasome R-HSA-5610783
TCF dependent signaling in response to WNT R-HSA-201681
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
MAPK1/MAPK3 signaling R-HSA-5684996
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of Apoptosis R-HSA-169911
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Deubiquitination R-HSA-5688426
Assembly of the pre-replicative complex R-HSA-68867
Intracellular signaling by second messengers R-HSA-9006925
DNA Replication R-HSA-69306
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by WNT R-HSA-195721
Interleukin-1 signaling R-HSA-9020702
Infectious disease R-HSA-5663205
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
Metabolism of amino acids and derivatives R-HSA-71291
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1 DNA Damage Response R-HSA-69563
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
MAPK family signaling cascades R-HSA-5683057
C-type lectin receptors (CLRs) R-HSA-5621481
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cellular response to hypoxia R-HSA-1234174

Expression Atlas ENSG00000205220
NCBI gene (formerly Entrezgene) 5699
GeneCards 9538
HGNC Symbol HGNC:9538
MIM gene 176847
MIM morbid 619175
UniProtKB Gene Name P40306
WikiGene 5699
Gene: MPL
Ensembl ID : ENSG00000117400
Description: MPL proto-oncogene, thrombopoietin receptor
Gene Synonyms: CD110,THPOR,TPOR
5 APIs:
186 Possible Orthologues:

Hemostasis R-HSA-109582
Platelet Aggregation (Plug Formation) R-HSA-76009
Platelet activation, signaling and aggregation R-HSA-76002
Platelet Aggregation (Plug Formation) R-HSA-76009
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Hemostasis R-HSA-109582
Platelet Aggregation (Plug Formation) R-HSA-76009
Platelet activation, signaling and aggregation R-HSA-76002
Platelet Aggregation (Plug Formation) R-HSA-76009
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Platelet Aggregation (Plug Formation) R-HSA-76009
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Platelet Aggregation (Plug Formation) R-HSA-76009
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Platelet Aggregation (Plug Formation) R-HSA-76009
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Platelet Aggregation (Plug Formation) R-HSA-76009
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Platelet Aggregation (Plug Formation) R-HSA-76009

Expression Atlas ENSG00000117400
LRG display in Ensembl gene LRG_510
NCBI gene (formerly Entrezgene) 4352
GeneCards 7217
HGNC Symbol HGNC:7217
MIM gene 159530
MIM morbid 604498
UniProtKB Gene Name Q5JUY5
WikiGene 4352
Gene: FNTA
Ensembl ID : ENSG00000168522
Description: farnesyltransferase, CAAX box, alpha
Gene Synonyms: FPTA,PGGT1A,PTAR2
2 APIs:
216 Possible Orthologues:

Signal Transduction R-HSA-162582
MAPK1/MAPK3 signaling R-HSA-5684996
The phototransduction cascade R-HSA-2514856
SARS-CoV Infections R-HSA-9679506
Programmed Cell Death R-HSA-5357801
Apoptosis R-HSA-109581
Potential therapeutics for SARS R-HSA-9679191
Sensory Perception R-HSA-9709957
Visual phototransduction R-HSA-2187338
Apoptotic execution phase R-HSA-75153
MAPK family signaling cascades R-HSA-5683057
RAS processing R-HSA-9648002
Infectious disease R-HSA-5663205
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859
Apoptotic cleavage of cellular proteins R-HSA-111465
RAF/MAP kinase cascade R-HSA-5673001
Disease R-HSA-1643685
Sensory Perception R-HSA-9709957
MAPK family signaling cascades R-HSA-5683057
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859
Disease R-HSA-1643685
Apoptosis R-HSA-109581
Programmed Cell Death R-HSA-5357801
Apoptotic cleavage of cellular proteins R-HSA-111465
The phototransduction cascade R-HSA-2514856
Potential therapeutics for SARS R-HSA-9679191
MAPK1/MAPK3 signaling R-HSA-5684996
Apoptotic execution phase R-HSA-75153
Visual phototransduction R-HSA-2187338
Signal Transduction R-HSA-162582
Infectious disease R-HSA-5663205
RAS processing R-HSA-9648002
SARS-CoV Infections R-HSA-9679506
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859
MAPK1/MAPK3 signaling R-HSA-5684996
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
Sensory Perception R-HSA-9709957
The phototransduction cascade R-HSA-2514856
Programmed Cell Death R-HSA-5357801
RAF/MAP kinase cascade R-HSA-5673001
Potential therapeutics for SARS R-HSA-9679191
Apoptotic execution phase R-HSA-75153
Disease R-HSA-1643685
Apoptosis R-HSA-109581
SARS-CoV Infections R-HSA-9679506
Apoptotic cleavage of cellular proteins R-HSA-111465
RAS processing R-HSA-9648002
Visual phototransduction R-HSA-2187338
Apoptosis R-HSA-109581
Potential therapeutics for SARS R-HSA-9679191
Sensory Perception R-HSA-9709957
MAPK family signaling cascades R-HSA-5683057
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859
Programmed Cell Death R-HSA-5357801
The phototransduction cascade R-HSA-2514856
RAS processing R-HSA-9648002
Apoptotic cleavage of cellular proteins R-HSA-111465
SARS-CoV Infections R-HSA-9679506
RAF/MAP kinase cascade R-HSA-5673001
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
Apoptotic execution phase R-HSA-75153
Visual phototransduction R-HSA-2187338
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
RAF/MAP kinase cascade R-HSA-5673001
Apoptosis R-HSA-109581
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Programmed Cell Death R-HSA-5357801
Apoptotic cleavage of cellular proteins R-HSA-111465
SARS-CoV Infections R-HSA-9679506
The phototransduction cascade R-HSA-2514856
Potential therapeutics for SARS R-HSA-9679191
RAS processing R-HSA-9648002
Infectious disease R-HSA-5663205
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859
Apoptotic execution phase R-HSA-75153
Visual phototransduction R-HSA-2187338
Sensory Perception R-HSA-9709957
RAS processing R-HSA-9648002
Infectious disease R-HSA-5663205
RAF/MAP kinase cascade R-HSA-5673001
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859
The phototransduction cascade R-HSA-2514856
Apoptotic execution phase R-HSA-75153
MAPK1/MAPK3 signaling R-HSA-5684996
Apoptosis R-HSA-109581
Programmed Cell Death R-HSA-5357801
Disease R-HSA-1643685
SARS-CoV Infections R-HSA-9679506
Sensory Perception R-HSA-9709957
Apoptotic cleavage of cellular proteins R-HSA-111465
Visual phototransduction R-HSA-2187338
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Potential therapeutics for SARS R-HSA-9679191
RAS processing R-HSA-9648002
Apoptosis R-HSA-109581
Programmed Cell Death R-HSA-5357801
MAPK1/MAPK3 signaling R-HSA-5684996
Apoptotic cleavage of cellular proteins R-HSA-111465
Potential therapeutics for SARS R-HSA-9679191
Sensory Perception R-HSA-9709957
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859
Apoptotic execution phase R-HSA-75153
Infectious disease R-HSA-5663205
SARS-CoV Infections R-HSA-9679506
The phototransduction cascade R-HSA-2514856
MAPK family signaling cascades R-HSA-5683057
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
Visual phototransduction R-HSA-2187338
MAPK1/MAPK3 signaling R-HSA-5684996
Apoptotic cleavage of cellular proteins R-HSA-111465
Programmed Cell Death R-HSA-5357801
SARS-CoV Infections R-HSA-9679506
RAS processing R-HSA-9648002
Infectious disease R-HSA-5663205
MAPK family signaling cascades R-HSA-5683057
Disease R-HSA-1643685
Apoptosis R-HSA-109581
Apoptotic execution phase R-HSA-75153
RAF/MAP kinase cascade R-HSA-5673001
Sensory Perception R-HSA-9709957
Visual phototransduction R-HSA-2187338
The phototransduction cascade R-HSA-2514856
Potential therapeutics for SARS R-HSA-9679191
Signal Transduction R-HSA-162582
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859
Sensory Perception R-HSA-9709957
RAF/MAP kinase cascade R-HSA-5673001
The phototransduction cascade R-HSA-2514856
RAS processing R-HSA-9648002
SARS-CoV Infections R-HSA-9679506
MAPK1/MAPK3 signaling R-HSA-5684996
Infectious disease R-HSA-5663205
Apoptosis R-HSA-109581
Apoptotic cleavage of cellular proteins R-HSA-111465
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Apoptotic execution phase R-HSA-75153
Programmed Cell Death R-HSA-5357801
Potential therapeutics for SARS R-HSA-9679191
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859
Disease R-HSA-1643685
Visual phototransduction R-HSA-2187338
Apoptotic execution phase R-HSA-75153
Potential therapeutics for SARS R-HSA-9679191
Signal Transduction R-HSA-162582
RAF/MAP kinase cascade R-HSA-5673001
Apoptotic cleavage of cellular proteins R-HSA-111465
Infectious disease R-HSA-5663205
MAPK1/MAPK3 signaling R-HSA-5684996
Visual phototransduction R-HSA-2187338
The phototransduction cascade R-HSA-2514856
MAPK family signaling cascades R-HSA-5683057
Programmed Cell Death R-HSA-5357801
Sensory Perception R-HSA-9709957
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859
Apoptosis R-HSA-109581
Disease R-HSA-1643685
RAS processing R-HSA-9648002
SARS-CoV Infections R-HSA-9679506
Apoptosis R-HSA-109581
Infectious disease R-HSA-5663205
Potential therapeutics for SARS R-HSA-9679191
Apoptotic cleavage of cellular proteins R-HSA-111465
Visual phototransduction R-HSA-2187338
Apoptotic execution phase R-HSA-75153
SARS-CoV Infections R-HSA-9679506
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859
MAPK family signaling cascades R-HSA-5683057
Programmed Cell Death R-HSA-5357801
MAPK1/MAPK3 signaling R-HSA-5684996
RAS processing R-HSA-9648002
RAF/MAP kinase cascade R-HSA-5673001
Sensory Perception R-HSA-9709957
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
The phototransduction cascade R-HSA-2514856

Expression Atlas ENSG00000168522
NCBI gene (formerly Entrezgene) 2339
GeneCards 3782
HGNC Symbol HGNC:3782
MIM gene 134635
UniProtKB Gene Name P49354
WikiGene 2339
Gene: PSMD3
Ensembl ID : ENSG00000108344
Description: proteasome 26S subunit, non-ATPase 3
Gene Synonyms: P58,RPN3,S3,TSTA2
5 APIs:
94 Possible Orthologues:

Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Apoptosis R-HSA-109581
Axon guidance R-HSA-422475
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of amino acids and derivatives R-HSA-71291
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of mitotic cell cycle R-HSA-453276
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Mitotic G1 phase and G1/S transition R-HSA-453279
Disease R-HSA-1643685
Mitotic Metaphase and Anaphase R-HSA-2555396
TCR signaling R-HSA-202403
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Switching of origins to a post-replicative state R-HSA-69052
Antigen processing-Cross presentation R-HSA-1236975
S Phase R-HSA-69242
Signaling by ROBO receptors R-HSA-376176
Asymmetric localization of PCP proteins R-HSA-4608870
ABC transporter disorders R-HSA-5619084
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC-family proteins mediated transport R-HSA-382556
Ub-specific processing proteases R-HSA-5689880
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
TCF dependent signaling in response to WNT R-HSA-201681
Stabilization of p53 R-HSA-69541
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neddylation R-HSA-8951664
Hh mutants are degraded by ERAD R-HSA-5362768
RNA Polymerase II Transcription R-HSA-73857
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Programmed Cell Death R-HSA-5357801
G2/M Transition R-HSA-69275
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Synthesis of DNA R-HSA-69239
Intracellular signaling by second messengers R-HSA-9006925
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
p53-Independent DNA Damage Response R-HSA-69610
Immune System R-HSA-168256
Signaling by NOTCH R-HSA-157118
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of Apoptosis R-HSA-169911
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Neutrophil degranulation R-HSA-6798695
RAF/MAP kinase cascade R-HSA-5673001
Degradation of AXIN R-HSA-4641257
Signaling by Hedgehog R-HSA-5358351
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
Adaptive Immune System R-HSA-1280218
UCH proteinases R-HSA-5689603
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transcriptional regulation by RUNX2 R-HSA-8878166
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by NOTCH4 R-HSA-9013694
Cytokine Signaling in Immune system R-HSA-1280215
Nervous system development R-HSA-9675108
Interleukin-1 family signaling R-HSA-446652
C-type lectin receptors (CLRs) R-HSA-5621481
Assembly of the pre-replicative complex R-HSA-68867
M Phase R-HSA-68886
Downstream TCR signaling R-HSA-202424
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of proteins R-HSA-392499
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Deubiquitination R-HSA-5688426
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle R-HSA-1640170
DNA Replication R-HSA-69306
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
KEAP1-NFE2L2 pathway R-HSA-9755511
Activation of NF-kappaB in B cells R-HSA-1169091
HIV Infection R-HSA-162906
ER-Phagosome pathway R-HSA-1236974
Axon guidance R-HSA-422475
Degradation of beta-catenin by the destruction complex R-HSA-195253
Gene expression (Transcription) R-HSA-74160
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Disorders of transmembrane transporters R-HSA-5619115
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism R-HSA-1430728
Cellular responses to stress R-HSA-2262752
Mitotic Anaphase R-HSA-68882
PIP3 activates AKT signaling R-HSA-1257604
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Separation of Sister Chromatids R-HSA-2467813
Infectious disease R-HSA-5663205
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK6/MAPK4 signaling R-HSA-5687128
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Orc1 removal from chromatin R-HSA-68949
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Checkpoints R-HSA-69481
PTEN Regulation R-HSA-6807070
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by WNT R-HSA-195721
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
FCERI mediated NF-kB activation R-HSA-2871837
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'on' state R-HSA-5632684
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 signaling R-HSA-9020702
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stimuli R-HSA-8953897
Transport of small molecules R-HSA-382551
DNA Replication Pre-Initiation R-HSA-69002
Apoptosis R-HSA-109581
Degradation of DVL R-HSA-4641258
Hedgehog ligand biogenesis R-HSA-5358346
MAPK1/MAPK3 signaling R-HSA-5684996
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G1/S Transition R-HSA-69206
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular response to hypoxia R-HSA-1234174
Regulation of RUNX2 expression and activity R-HSA-8939902
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Neddylation R-HSA-8951664
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
M Phase R-HSA-68886
Stabilization of p53 R-HSA-69541
Cellular responses to stimuli R-HSA-8953897
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of proteins R-HSA-392499
RAF/MAP kinase cascade R-HSA-5673001
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCR signaling R-HSA-202403
Asymmetric localization of PCP proteins R-HSA-4608870
G1/S DNA Damage Checkpoints R-HSA-69615
Deubiquitination R-HSA-5688426
Metabolism R-HSA-1430728
Generic Transcription Pathway R-HSA-212436
Nervous system development R-HSA-9675108
HIV Infection R-HSA-162906
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Axon guidance R-HSA-422475
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle Checkpoints R-HSA-69620
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RNA Polymerase II Transcription R-HSA-73857
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of polyamines R-HSA-351202
PCP/CE pathway R-HSA-4086400
Disorders of transmembrane transporters R-HSA-5619115
Orc1 removal from chromatin R-HSA-68949
Cellular response to hypoxia R-HSA-1234174
KEAP1-NFE2L2 pathway R-HSA-9755511
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH4 R-HSA-9013694
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
S Phase R-HSA-69242
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
Metabolism of amino acids and derivatives R-HSA-71291
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Regulation of Apoptosis R-HSA-169911
Degradation of DVL R-HSA-4641258
DNA Replication R-HSA-69306
Degradation of GLI2 by the proteasome R-HSA-5610783
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
Signaling by WNT R-HSA-195721
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle, Mitotic R-HSA-69278
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hh mutants abrogate ligand secretion R-HSA-5387390
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Separation of Sister Chromatids R-HSA-2467813
p53-Independent DNA Damage Response R-HSA-69610
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stress R-HSA-2262752
Mitotic G1 phase and G1/S transition R-HSA-453279
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transport of small molecules R-HSA-382551
Transcriptional regulation by RUNX2 R-HSA-8878166
Adaptive Immune System R-HSA-1280218
Signaling by Interleukins R-HSA-449147
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of RNA R-HSA-8953854
Gene expression (Transcription) R-HSA-74160
Programmed Cell Death R-HSA-5357801
Vpu mediated degradation of CD4 R-HSA-180534
Neutrophil degranulation R-HSA-6798695
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-1 signaling R-HSA-9020702
MAPK6/MAPK4 signaling R-HSA-5687128
Synthesis of DNA R-HSA-69239
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Developmental Biology R-HSA-1266738
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK1/MAPK3 signaling R-HSA-5684996
DNA Replication Pre-Initiation R-HSA-69002
MAPK family signaling cascades R-HSA-5683057
Downstream TCR signaling R-HSA-202424
Antigen processing-Cross presentation R-HSA-1236975
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of AXIN R-HSA-4641257
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
C-type lectin receptors (CLRs) R-HSA-5621481
Ub-specific processing proteases R-HSA-5689880
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Transition R-HSA-69275
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PTEN Regulation R-HSA-6807070
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cytokine Signaling in Immune system R-HSA-1280215
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Innate Immune System R-HSA-168249
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
UCH proteinases R-HSA-5689603
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'on' state R-HSA-5632684
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
ABC-family proteins mediated transport R-HSA-382556
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 family signaling R-HSA-446652
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by NOTCH R-HSA-157118
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of mitotic cell cycle R-HSA-453276
Mitotic Anaphase R-HSA-68882
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
Vpu mediated degradation of CD4 R-HSA-180534
Nervous system development R-HSA-9675108
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Developmental Biology R-HSA-1266738
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RAS by GAPs R-HSA-5658442
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G1/S Transition R-HSA-69206
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
Signaling by NOTCH R-HSA-157118
TCR signaling R-HSA-202403
S Phase R-HSA-69242
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of GLI1 by the proteasome R-HSA-5610780
Cell Cycle Checkpoints R-HSA-69620
Signal Transduction R-HSA-162582
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of polyamines R-HSA-351202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
ABC transporter disorders R-HSA-5619084
Degradation of DVL R-HSA-4641258
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
RNA Polymerase II Transcription R-HSA-73857
PCP/CE pathway R-HSA-4086400
PTEN Regulation R-HSA-6807070
Programmed Cell Death R-HSA-5357801
Downstream TCR signaling R-HSA-202424
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of beta-catenin by the destruction complex R-HSA-195253
Ub-specific processing proteases R-HSA-5689880
Cellular response to chemical stress R-HSA-9711123
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by NOTCH4 R-HSA-9013694
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cyclin E associated events during G1/S transition R-HSA-69202
UCH proteinases R-HSA-5689603
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI2 by the proteasome R-HSA-5610783
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neddylation R-HSA-8951664
Hedgehog 'off' state R-HSA-5610787
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of AXIN R-HSA-4641257
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
p53-Dependent G1 DNA Damage Response R-HSA-69563
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
DNA Replication Pre-Initiation R-HSA-69002
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular response to hypoxia R-HSA-1234174
C-type lectin receptors (CLRs) R-HSA-5621481
Switching of origins to a post-replicative state R-HSA-69052
Mitotic Anaphase R-HSA-68882
Transport of small molecules R-HSA-382551
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by Hedgehog R-HSA-5358351
Apoptosis R-HSA-109581
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cytokine Signaling in Immune system R-HSA-1280215
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Activation of NF-kappaB in B cells R-HSA-1169091
HIV Infection R-HSA-162906
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RUNX2 expression and activity R-HSA-8939902
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Gene expression (Transcription) R-HSA-74160
DNA Replication R-HSA-69306
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Infectious disease R-HSA-5663205
Regulation of mitotic cell cycle R-HSA-453276
Intracellular signaling by second messengers R-HSA-9006925
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Axon guidance R-HSA-422475
p53-Independent DNA Damage Response R-HSA-69610
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
ER-Phagosome pathway R-HSA-1236974
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of amino acids and derivatives R-HSA-71291
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by Interleukins R-HSA-449147
Separation of Sister Chromatids R-HSA-2467813
RAF/MAP kinase cascade R-HSA-5673001
TCF dependent signaling in response to WNT R-HSA-201681
Antigen processing-Cross presentation R-HSA-1236975
Neutrophil degranulation R-HSA-6798695
Interleukin-1 signaling R-HSA-9020702
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Stabilization of p53 R-HSA-69541
Adaptive Immune System R-HSA-1280218
Assembly of the pre-replicative complex R-HSA-68867
Deubiquitination R-HSA-5688426
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of RNA R-HSA-8953854
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Mitotic G2-G2/M phases R-HSA-453274
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of proteins R-HSA-392499
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX2 R-HSA-8878166
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by ROBO receptors R-HSA-376176
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Vif-mediated degradation of APOBEC3G R-HSA-180585
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
DNA Replication R-HSA-69306
Transcriptional regulation by RUNX2 R-HSA-8878166
Antigen processing-Cross presentation R-HSA-1236975
PTEN Regulation R-HSA-6807070
Regulation of RAS by GAPs R-HSA-5658442
PCP/CE pathway R-HSA-4086400
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Separation of Sister Chromatids R-HSA-2467813
Hh mutants are degraded by ERAD R-HSA-5362768
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transport of small molecules R-HSA-382551
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
Vpu mediated degradation of CD4 R-HSA-180534
S Phase R-HSA-69242
Cellular response to hypoxia R-HSA-1234174
MAPK1/MAPK3 signaling R-HSA-5684996
Assembly of the pre-replicative complex R-HSA-68867
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Infectious disease R-HSA-5663205
Cell Cycle R-HSA-1640170
Cytokine Signaling in Immune system R-HSA-1280215
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin E associated events during G1/S transition R-HSA-69202
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
M Phase R-HSA-68886
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Generic Transcription Pathway R-HSA-212436
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog ligand biogenesis R-HSA-5358346
ABC transporter disorders R-HSA-5619084
Ub-specific processing proteases R-HSA-5689880
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by ROBO receptors R-HSA-376176
Interleukin-1 family signaling R-HSA-446652
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Synthesis of DNA R-HSA-69239
Degradation of DVL R-HSA-4641258
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Switching of origins to a post-replicative state R-HSA-69052
Programmed Cell Death R-HSA-5357801
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by Interleukins R-HSA-449147
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Adaptive Immune System R-HSA-1280218
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Independent DNA Damage Response R-HSA-69610
RAF/MAP kinase cascade R-HSA-5673001
Mitotic Anaphase R-HSA-68882
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Degradation of AXIN R-HSA-4641257
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
Degradation of beta-catenin by the destruction complex R-HSA-195253
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of GLI1 by the proteasome R-HSA-5610780
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of Apoptosis R-HSA-169911
Signaling by WNT R-HSA-195721
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
Cellular response to chemical stress R-HSA-9711123
G2/M Transition R-HSA-69275
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Asymmetric localization of PCP proteins R-HSA-4608870
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Apoptosis R-HSA-109581
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH4 R-HSA-9013694
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of polyamines R-HSA-351202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
HIV Infection R-HSA-162906
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G2/M Checkpoints R-HSA-69481
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transcriptional regulation by RUNX1 R-HSA-8878171
Post-translational protein modification R-HSA-597592
Immune System R-HSA-168256
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of proteins R-HSA-392499
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX3 R-HSA-8878159
Neutrophil degranulation R-HSA-6798695
Degradation of GLI2 by the proteasome R-HSA-5610783
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
Signaling by NOTCH R-HSA-157118
Metabolism of RNA R-HSA-8953854
Nervous system development R-HSA-9675108
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of PTEN stability and activity R-HSA-8948751
KEAP1-NFE2L2 pathway R-HSA-9755511
Signal Transduction R-HSA-162582
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stimuli R-HSA-8953897
Activation of NF-kappaB in B cells R-HSA-1169091
TCF dependent signaling in response to WNT R-HSA-201681
G1/S Transition R-HSA-69206
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'on' state R-HSA-5632684
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RUNX2 expression and activity R-HSA-8939902
Disorders of transmembrane transporters R-HSA-5619115
Neddylation R-HSA-8951664
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stress R-HSA-2262752
Defective CFTR causes cystic fibrosis R-HSA-5678895
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
Switching of origins to a post-replicative state R-HSA-69052
Regulation of RAS by GAPs R-HSA-5658442
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle, Mitotic R-HSA-69278
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular response to hypoxia R-HSA-1234174
ABC transporter disorders R-HSA-5619084
Cell Cycle R-HSA-1640170
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ER-Phagosome pathway R-HSA-1236974
Hedgehog ligand biogenesis R-HSA-5358346
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neddylation R-HSA-8951664
Cell Cycle Checkpoints R-HSA-69620
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by NOTCH R-HSA-157118
M Phase R-HSA-68886
Adaptive Immune System R-HSA-1280218
Apoptosis R-HSA-109581
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Gene expression (Transcription) R-HSA-74160
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic G1 phase and G1/S transition R-HSA-453279
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
Intracellular signaling by second messengers R-HSA-9006925
DNA Replication Pre-Initiation R-HSA-69002
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants are degraded by ERAD R-HSA-5362768
p53-Dependent G1 DNA Damage Response R-HSA-69563
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX2 R-HSA-8878166
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Class I MHC mediated antigen processing & presentation R-HSA-983169
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Post-translational protein modification R-HSA-597592
Hedgehog 'on' state R-HSA-5632684
RNA Polymerase II Transcription R-HSA-73857
Ub-specific processing proteases R-HSA-5689880
Mitotic G2-G2/M phases R-HSA-453274
Beta-catenin independent WNT signaling R-HSA-3858494
Signal Transduction R-HSA-162582
Signaling by WNT R-HSA-195721
Signaling by Hedgehog R-HSA-5358351
Disorders of transmembrane transporters R-HSA-5619115
Metabolism R-HSA-1430728
Degradation of beta-catenin by the destruction complex R-HSA-195253
Synthesis of DNA R-HSA-69239
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic Anaphase R-HSA-68882
p53-Independent DNA Damage Response R-HSA-69610
TCR signaling R-HSA-202403
Nuclear events mediated by NFE2L2 R-HSA-9759194
Downstream TCR signaling R-HSA-202424
Deubiquitination R-HSA-5688426
Signaling by ROBO receptors R-HSA-376176
MAPK6/MAPK4 signaling R-HSA-5687128
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of AXIN R-HSA-4641257
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX3 R-HSA-8878159
Infectious disease R-HSA-5663205
Regulation of RUNX2 expression and activity R-HSA-8939902
FCERI mediated NF-kB activation R-HSA-2871837
Transport of small molecules R-HSA-382551
Regulation of Apoptosis R-HSA-169911
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Nervous system development R-HSA-9675108
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Separation of Sister Chromatids R-HSA-2467813
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
PIP3 activates AKT signaling R-HSA-1257604
Axon guidance R-HSA-422475
Orc1 removal from chromatin R-HSA-68949
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Stabilization of p53 R-HSA-69541
G1/S DNA Damage Checkpoints R-HSA-69615
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PCP/CE pathway R-HSA-4086400
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hh mutants abrogate ligand secretion R-HSA-5387390
PTEN Regulation R-HSA-6807070
Mitotic Metaphase and Anaphase R-HSA-2555396
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by NOTCH4 R-HSA-9013694
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX3 expression and activity R-HSA-8941858
Programmed Cell Death R-HSA-5357801
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cytokine Signaling in Immune system R-HSA-1280215
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of RNA R-HSA-8953854
G2/M Checkpoints R-HSA-69481
Metabolism of proteins R-HSA-392499
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RAF/MAP kinase cascade R-HSA-5673001
HIV Infection R-HSA-162906
Metabolism of polyamines R-HSA-351202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
NIK-->noncanonical NF-kB signaling R-HSA-5676590
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Neutrophil degranulation R-HSA-6798695
UCH proteinases R-HSA-5689603
Cellular response to chemical stress R-HSA-9711123
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G1/S Transition R-HSA-69206
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Immune System R-HSA-168256
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1 DNA Damage Response R-HSA-69563
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by NOTCH4 R-HSA-9013694
Neddylation R-HSA-8951664
Signaling by WNT R-HSA-195721
Cell Cycle Checkpoints R-HSA-69620
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Post-translational protein modification R-HSA-597592
Signaling by ROBO receptors R-HSA-376176
Downstream TCR signaling R-HSA-202424
Signal Transduction R-HSA-162582
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Developmental Biology R-HSA-1266738
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular response to chemical stress R-HSA-9711123
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Hedgehog R-HSA-5358351
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication R-HSA-69306
Stabilization of p53 R-HSA-69541
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle, Mitotic R-HSA-69278
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
M Phase R-HSA-68886
Infectious disease R-HSA-5663205
Mitotic G2-G2/M phases R-HSA-453274
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
DNA Replication Pre-Initiation R-HSA-69002
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vif-mediated degradation of APOBEC3G R-HSA-180585
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK6/MAPK4 signaling R-HSA-5687128
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of polyamines R-HSA-351202
Defective CFTR causes cystic fibrosis R-HSA-5678895
Axon guidance R-HSA-422475
PCP/CE pathway R-HSA-4086400
Degradation of DVL R-HSA-4641258
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ub-specific processing proteases R-HSA-5689880
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RAF/MAP kinase cascade R-HSA-5673001
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Separation of Sister Chromatids R-HSA-2467813
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of amino acids and derivatives R-HSA-71291
Innate Immune System R-HSA-168249
Assembly of the pre-replicative complex R-HSA-68867
Programmed Cell Death R-HSA-5357801
Switching of origins to a post-replicative state R-HSA-69052
Deubiquitination R-HSA-5688426
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Anaphase R-HSA-68882
Disease R-HSA-1643685
Degradation of beta-catenin by the destruction complex R-HSA-195253
Mitotic G1 phase and G1/S transition R-HSA-453279
Generic Transcription Pathway R-HSA-212436
Metabolism R-HSA-1430728
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
G2/M Checkpoints R-HSA-69481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Beta-catenin independent WNT signaling R-HSA-3858494
Gene expression (Transcription) R-HSA-74160
Nuclear events mediated by NFE2L2 R-HSA-9759194
KEAP1-NFE2L2 pathway R-HSA-9755511
UCH proteinases R-HSA-5689603
Vpu mediated degradation of CD4 R-HSA-180534
ABC-family proteins mediated transport R-HSA-382556
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cytokine Signaling in Immune system R-HSA-1280215
Neutrophil degranulation R-HSA-6798695
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
MAPK family signaling cascades R-HSA-5683057
G1/S Transition R-HSA-69206
Interleukin-1 family signaling R-HSA-446652
ABC transporter disorders R-HSA-5619084
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ER-Phagosome pathway R-HSA-1236974
PTEN Regulation R-HSA-6807070
CLEC7A (Dectin-1) signaling R-HSA-5607764
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular responses to stress R-HSA-2262752
Signaling by NOTCH R-HSA-157118
Cell Cycle R-HSA-1640170
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by Interleukins R-HSA-449147
Host Interactions of HIV factors R-HSA-162909
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog ligand biogenesis R-HSA-5358346
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX1 R-HSA-8878171
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of proteins R-HSA-392499
HIV Infection R-HSA-162906
Regulation of RUNX2 expression and activity R-HSA-8939902
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX2 R-HSA-8878166
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
Cellular response to hypoxia R-HSA-1234174
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transport of small molecules R-HSA-382551
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nervous system development R-HSA-9675108
TCR signaling R-HSA-202403
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of RNA R-HSA-8953854
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of Apoptosis R-HSA-169911
Synthesis of DNA R-HSA-69239
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of AXIN R-HSA-4641257
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular responses to stress R-HSA-2262752
MAPK1/MAPK3 signaling R-HSA-5684996
ABC-family proteins mediated transport R-HSA-382556
Beta-catenin independent WNT signaling R-HSA-3858494
ABC transporter disorders R-HSA-5619084
Post-translational protein modification R-HSA-597592
Hh mutants abrogate ligand secretion R-HSA-5387390
Asymmetric localization of PCP proteins R-HSA-4608870
Mitotic G2-G2/M phases R-HSA-453274
Metabolism R-HSA-1430728
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
M Phase R-HSA-68886
MAPK family signaling cascades R-HSA-5683057
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
RNA Polymerase II Transcription R-HSA-73857
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Separation of Sister Chromatids R-HSA-2467813
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Adaptive Immune System R-HSA-1280218
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular response to chemical stress R-HSA-9711123
PCP/CE pathway R-HSA-4086400
p53-Independent DNA Damage Response R-HSA-69610
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Nervous system development R-HSA-9675108
Regulation of RUNX2 expression and activity R-HSA-8939902
Hh mutants are degraded by ERAD R-HSA-5362768
Assembly of the pre-replicative complex R-HSA-68867
DNA Replication R-HSA-69306
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S Transition R-HSA-69206
Cellular responses to stimuli R-HSA-8953897
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Negative regulation of NOTCH4 signaling R-HSA-9604323
HIV Infection R-HSA-162906
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signal Transduction R-HSA-162582
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Immune System R-HSA-168256
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Switching of origins to a post-replicative state R-HSA-69052
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 family signaling R-HSA-446652
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hedgehog 'off' state R-HSA-5610787
Transport of small molecules R-HSA-382551
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Vif-mediated degradation of APOBEC3G R-HSA-180585
Downstream TCR signaling R-HSA-202424
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
Apoptosis R-HSA-109581
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mitotic cell cycle R-HSA-453276
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RAS by GAPs R-HSA-5658442
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FCERI mediated NF-kB activation R-HSA-2871837
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog 'on' state R-HSA-5632684
TCF dependent signaling in response to WNT R-HSA-201681
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Programmed Cell Death R-HSA-5357801
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Interleukin-1 signaling R-HSA-9020702
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cell Cycle, Mitotic R-HSA-69278
Stabilization of p53 R-HSA-69541
Hedgehog ligand biogenesis R-HSA-5358346
Innate Immune System R-HSA-168249
Intracellular signaling by second messengers R-HSA-9006925
Antigen processing-Cross presentation R-HSA-1236975
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of proteins R-HSA-392499
Mitotic Anaphase R-HSA-68882
Vpu mediated degradation of CD4 R-HSA-180534
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Axon guidance R-HSA-422475
Neutrophil degranulation R-HSA-6798695
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
S Phase R-HSA-69242
Cellular response to hypoxia R-HSA-1234174
p53-Dependent G1 DNA Damage Response R-HSA-69563
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCR signaling R-HSA-202403
Cell Cycle R-HSA-1640170
Stabilization of p53 R-HSA-69541
C-type lectin receptors (CLRs) R-HSA-5621481
Deubiquitination R-HSA-5688426
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
Post-translational protein modification R-HSA-597592
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events mediated by NFE2L2 R-HSA-9759194
PTEN Regulation R-HSA-6807070
Metabolism of RNA R-HSA-8953854
Cell Cycle Checkpoints R-HSA-69620
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic Metaphase and Anaphase R-HSA-2555396
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Apoptosis R-HSA-109581
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Degradation of AXIN R-HSA-4641257
Hedgehog 'on' state R-HSA-5632684
ABC transporter disorders R-HSA-5619084
Signaling by Interleukins R-HSA-449147
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by NOTCH R-HSA-157118
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX1 R-HSA-8878171
G1/S Transition R-HSA-69206
ABC-family proteins mediated transport R-HSA-382556
Disease R-HSA-1643685
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Independent DNA Damage Response R-HSA-69610
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Assembly of the pre-replicative complex R-HSA-68867
CLEC7A (Dectin-1) signaling R-HSA-5607764
ER-Phagosome pathway R-HSA-1236974
Innate Immune System R-HSA-168249
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
G1/S DNA Damage Checkpoints R-HSA-69615
Defective CFTR causes cystic fibrosis R-HSA-5678895
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX3 expression and activity R-HSA-8941858
Adaptive Immune System R-HSA-1280218
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle, Mitotic R-HSA-69278
Metabolism of proteins R-HSA-392499
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX2 R-HSA-8878166
Disorders of transmembrane transporters R-HSA-5619115
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of Apoptosis R-HSA-169911
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of RAS by GAPs R-HSA-5658442
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neutrophil degranulation R-HSA-6798695
Infectious disease R-HSA-5663205
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
Host Interactions of HIV factors R-HSA-162909
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Developmental Biology R-HSA-1266738
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stimuli R-HSA-8953897
Downstream TCR signaling R-HSA-202424
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX3 R-HSA-8878159
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hh mutants abrogate ligand secretion R-HSA-5387390
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
DNA Replication R-HSA-69306
Regulation of mitotic cell cycle R-HSA-453276
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog 'off' state R-HSA-5610787
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of amino acids and derivatives R-HSA-71291
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
Hh mutants are degraded by ERAD R-HSA-5362768
Nervous system development R-HSA-9675108
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stress R-HSA-2262752
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Intracellular signaling by second messengers R-HSA-9006925
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
Asymmetric localization of PCP proteins R-HSA-4608870
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
TCF dependent signaling in response to WNT R-HSA-201681
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
G2/M Transition R-HSA-69275
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ub-specific processing proteases R-HSA-5689880
Activation of NF-kappaB in B cells R-HSA-1169091
Orc1 removal from chromatin R-HSA-68949
PCP/CE pathway R-HSA-4086400
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog ligand biogenesis R-HSA-5358346
Gene expression (Transcription) R-HSA-74160
Neddylation R-HSA-8951664
Signaling by WNT R-HSA-195721
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by ROBO receptors R-HSA-376176
Transport of small molecules R-HSA-382551
Separation of Sister Chromatids R-HSA-2467813
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCR signaling R-HSA-202403
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of PTEN stability and activity R-HSA-8948751
MAPK6/MAPK4 signaling R-HSA-5687128

Expression Atlas ENSG00000108344
NCBI gene (formerly Entrezgene) 5709
GeneCards 9560
HGNC Symbol HGNC:9560
MIM gene 617676
UniProtKB Gene Name O43242
WikiGene 5709
Gene: GABRE
Ensembl ID : ENSG00000102287
Description: gamma-aminobutyric acid type A receptor subunit epsilon
Gene Synonyms:
64 APIs:
109 Possible Orthologues:

Expression Atlas ENSG00000102287
NCBI gene (formerly Entrezgene) 2564
GeneCards 4085
HGNC Symbol HGNC:4085
MIM gene 300093
UniProtKB Gene Name P78334
WikiGene 2564