Gene: FGFR2
Ensembl ID : ENSG00000066468
Description: fibroblast growth factor receptor 2
Gene Synonyms: BEK,CD332,CEK3,CFD1,ECT1,JWS,K-SAM,KGFR,TK14,TK25
27 APIs:
218 Possible Orthologues:

Activated point mutants of FGFR2 R-HSA-2033519
PI3K Cascade R-HSA-109704
FGFR2b ligand binding and activation R-HSA-190377
FGFR2 alternative splicing R-HSA-6803529
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FGFR2c ligand binding and activation R-HSA-190375
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR in disease R-HSA-1226099
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Insulin receptor R-HSA-74752
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by FGFR R-HSA-190236
Signaling by FGFR2 IIIa TM R-HSA-8851708
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by FGFR2 R-HSA-5654738
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 amplification mutants R-HSA-2023837
FGFR2 ligand binding and activation R-HSA-190241
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
FGFR2 mutant receptor activation R-HSA-1839126
Insulin receptor signalling cascade R-HSA-74751
SHC-mediated cascade:FGFR2 R-HSA-5654699
PIP3 activates AKT signaling R-HSA-1257604
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by FGFR2 fusions R-HSA-8853333
IRS-mediated signalling R-HSA-112399
Negative regulation of the PI3K/AKT network R-HSA-199418
Negative regulation of FGFR2 signaling R-HSA-5654727
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Disease R-HSA-1643685
Signaling by FGFR2 fusions R-HSA-8853333
IRS-mediated signalling R-HSA-112399
Signaling by FGFR2 in disease R-HSA-5655253
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
FGFR2c ligand binding and activation R-HSA-190375
Insulin receptor signalling cascade R-HSA-74751
FGFR2 ligand binding and activation R-HSA-190241
FGFR2b ligand binding and activation R-HSA-190377
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Downstream signaling of activated FGFR2 R-HSA-5654696
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IGF1R signaling cascade R-HSA-2428924
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR R-HSA-190236
PI3K Cascade R-HSA-109704
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR in disease R-HSA-1226099
Negative regulation of FGFR2 signaling R-HSA-5654727
Activated point mutants of FGFR2 R-HSA-2033519
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 R-HSA-5654738
FGFR2 mutant receptor activation R-HSA-1839126
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by FGFR2 IIIa TM R-HSA-8851708
IRS-related events triggered by IGF1R R-HSA-2428928
PI-3K cascade:FGFR2 R-HSA-5654695
FGFR2 alternative splicing R-HSA-6803529
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Activated point mutants of FGFR2 R-HSA-2033519
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling of activated FGFR2 R-HSA-5654696
FGFR2 alternative splicing R-HSA-6803529
FGFR2c ligand binding and activation R-HSA-190375
Signal Transduction R-HSA-162582
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by FGFR2 IIIa TM R-HSA-8851708
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 amplification mutants R-HSA-2023837
FGFR2 ligand binding and activation R-HSA-190241
Negative regulation of the PI3K/AKT network R-HSA-199418
FGFR2 mutant receptor activation R-HSA-1839126
PI3K Cascade R-HSA-109704
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
IRS-mediated signalling R-HSA-112399
Signaling by FGFR in disease R-HSA-1226099
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR R-HSA-190236
IGF1R signaling cascade R-HSA-2428924
FGFR2b ligand binding and activation R-HSA-190377
Disease R-HSA-1643685
Signaling by Insulin receptor R-HSA-74752
PI3K/AKT Signaling in Cancer R-HSA-2219528
Insulin receptor signalling cascade R-HSA-74751
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR2 in disease R-HSA-5655253
RAF/MAP kinase cascade R-HSA-5673001
FRS-mediated FGFR2 signaling R-HSA-5654700
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 in disease R-HSA-5655253
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FGFR2 ligand binding and activation R-HSA-190241
MAPK1/MAPK3 signaling R-HSA-5684996
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR2 IIIa TM R-HSA-8851708
Disease R-HSA-1643685
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2c ligand binding and activation R-HSA-190375
Signaling by FGFR R-HSA-190236
Downstream signaling of activated FGFR2 R-HSA-5654696
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR in disease R-HSA-1226099
PI3K Cascade R-HSA-109704
IRS-mediated signalling R-HSA-112399
Insulin receptor signalling cascade R-HSA-74751
IGF1R signaling cascade R-HSA-2428924
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR2 R-HSA-5654738
PIP3 activates AKT signaling R-HSA-1257604
FRS-mediated FGFR2 signaling R-HSA-5654700
SHC-mediated cascade:FGFR2 R-HSA-5654699
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FGFR2b ligand binding and activation R-HSA-190377
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by Insulin receptor R-HSA-74752
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI-3K cascade:FGFR2 R-HSA-5654695
IRS-related events triggered by IGF1R R-HSA-2428928
MAPK family signaling cascades R-HSA-5683057
IRS-mediated signalling R-HSA-112399
PIP3 activates AKT signaling R-HSA-1257604
Signaling by FGFR2 IIIa TM R-HSA-8851708
FGFR2 ligand binding and activation R-HSA-190241
PI3K Cascade R-HSA-109704
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by FGFR2 in disease R-HSA-5655253
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2b ligand binding and activation R-HSA-190377
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR2 amplification mutants R-HSA-2023837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Signaling by FGFR in disease R-HSA-1226099
FGFR2c ligand binding and activation R-HSA-190375
RAF/MAP kinase cascade R-HSA-5673001
PI3K/AKT Signaling in Cancer R-HSA-2219528
SHC-mediated cascade:FGFR2 R-HSA-5654699
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
FRS-mediated FGFR2 signaling R-HSA-5654700
Disease R-HSA-1643685
IRS-related events triggered by IGF1R R-HSA-2428928
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
FGFR2 alternative splicing R-HSA-6803529
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR R-HSA-190236
IGF1R signaling cascade R-HSA-2428924
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 in disease R-HSA-5655253
FGFR2c ligand binding and activation R-HSA-190375
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
Negative regulation of the PI3K/AKT network R-HSA-199418
FGFR2 ligand binding and activation R-HSA-190241
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
MAPK1/MAPK3 signaling R-HSA-5684996
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 amplification mutants R-HSA-2023837
IRS-related events triggered by IGF1R R-HSA-2428928
Negative regulation of FGFR2 signaling R-HSA-5654727
RAF/MAP kinase cascade R-HSA-5673001
IRS-mediated signalling R-HSA-112399
IGF1R signaling cascade R-HSA-2428924
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by FGFR2 IIIa TM R-HSA-8851708
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR in disease R-HSA-1226099
PI3K Cascade R-HSA-109704
MAPK family signaling cascades R-HSA-5683057
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Disease R-HSA-1643685
Downstream signaling of activated FGFR2 R-HSA-5654696
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR R-HSA-190236
Intracellular signaling by second messengers R-HSA-9006925
FRS-mediated FGFR2 signaling R-HSA-5654700
FGFR2 mutant receptor activation R-HSA-1839126
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2b ligand binding and activation R-HSA-190377
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Insulin receptor signalling cascade R-HSA-74751
IGF1R signaling cascade R-HSA-2428924
PIP3 activates AKT signaling R-HSA-1257604
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K Cascade R-HSA-109704
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR R-HSA-190236
Signaling by FGFR2 amplification mutants R-HSA-2023837
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2 mutant receptor activation R-HSA-1839126
Signal Transduction R-HSA-162582
FRS-mediated FGFR2 signaling R-HSA-5654700
IRS-mediated signalling R-HSA-112399
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 IIIa TM R-HSA-8851708
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR in disease R-HSA-1226099
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Negative regulation of FGFR2 signaling R-HSA-5654727
PI3K/AKT Signaling in Cancer R-HSA-2219528
Disease R-HSA-1643685
FGFR2c ligand binding and activation R-HSA-190375
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FGFR2 ligand binding and activation R-HSA-190241
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 in disease R-HSA-5655253
IRS-related events triggered by IGF1R R-HSA-2428928
FGFR2 alternative splicing R-HSA-6803529
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling of activated FGFR2 R-HSA-5654696
Insulin receptor signalling cascade R-HSA-74751
FGFR2b ligand binding and activation R-HSA-190377
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IGF1R signaling cascade R-HSA-2428924
Activated point mutants of FGFR2 R-HSA-2033519
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 amplification mutants R-HSA-2023837
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
SHC-mediated cascade:FGFR2 R-HSA-5654699
PIP3 activates AKT signaling R-HSA-1257604
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by FGFR2 fusions R-HSA-8853333
Downstream signaling of activated FGFR2 R-HSA-5654696
FGFR2c ligand binding and activation R-HSA-190375
Negative regulation of FGFR2 signaling R-HSA-5654727
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR2 IIIa TM R-HSA-8851708
Disease R-HSA-1643685
FGFR2 ligand binding and activation R-HSA-190241
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR R-HSA-190236
PI-3K cascade:FGFR2 R-HSA-5654695
FGFR2b ligand binding and activation R-HSA-190377
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR2 in disease R-HSA-5655253
IRS-mediated signalling R-HSA-112399
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR in disease R-HSA-1226099
IRS-related events triggered by IGF1R R-HSA-2428928
PI3K Cascade R-HSA-109704
FGFR2 alternative splicing R-HSA-6803529
Signal Transduction R-HSA-162582
FGFR2 mutant receptor activation R-HSA-1839126
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 in disease R-HSA-5655253
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by FGFR2 amplification mutants R-HSA-2023837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR in disease R-HSA-1226099
Disease R-HSA-1643685
Negative regulation of FGFR2 signaling R-HSA-5654727
PIP3 activates AKT signaling R-HSA-1257604
FGFR2 mutant receptor activation R-HSA-1839126
Signaling by FGFR2 IIIa TM R-HSA-8851708
Signaling by FGFR R-HSA-190236
Signal Transduction R-HSA-162582
FGFR2b ligand binding and activation R-HSA-190377
IRS-mediated signalling R-HSA-112399
FGFR2c ligand binding and activation R-HSA-190375
IGF1R signaling cascade R-HSA-2428924
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
IRS-related events triggered by IGF1R R-HSA-2428928
PI3K Cascade R-HSA-109704
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Insulin receptor R-HSA-74752
PI-3K cascade:FGFR2 R-HSA-5654695
Negative regulation of the PI3K/AKT network R-HSA-199418
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2 ligand binding and activation R-HSA-190241
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
SHC-mediated cascade:FGFR2 R-HSA-5654699
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 IIIa TM R-HSA-8851708
SHC-mediated cascade:FGFR2 R-HSA-5654699
FGFR2b ligand binding and activation R-HSA-190377
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 in disease R-HSA-5655253
IRS-related events triggered by IGF1R R-HSA-2428928
MAPK family signaling cascades R-HSA-5683057
FGFR2c ligand binding and activation R-HSA-190375
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR2 R-HSA-5654738
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR2 fusions R-HSA-8853333
Negative regulation of FGFR2 signaling R-HSA-5654727
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR R-HSA-190236
Activated point mutants of FGFR2 R-HSA-2033519
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Disease R-HSA-1643685
PI-3K cascade:FGFR2 R-HSA-5654695
MAPK1/MAPK3 signaling R-HSA-5684996
FRS-mediated FGFR2 signaling R-HSA-5654700
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
PI3K Cascade R-HSA-109704
Signaling by FGFR in disease R-HSA-1226099
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2 ligand binding and activation R-HSA-190241
FGFR2 alternative splicing R-HSA-6803529
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS-mediated signalling R-HSA-112399

Expression Atlas ENSG00000066468
LRG display in Ensembl gene LRG_994
NCBI gene (formerly Entrezgene) 2263
GeneCards 3689
HGNC Symbol HGNC:3689
MIM gene 176943
MIM morbid 614592
UniProtKB Gene Name S4R3B2
WikiGene 2263
Gene: LCK
Ensembl ID : ENSG00000182866
Description: LCK proto-oncogene, Src family tyrosine kinase
Gene Synonyms:
2 APIs:
120 Possible Orthologues:

Generation of second messenger molecules R-HSA-202433
Negative regulation of the PI3K/AKT network R-HSA-199418
Cell surface interactions at the vascular wall R-HSA-202733
Infectious disease R-HSA-5663205
Adaptive Immune System R-HSA-1280218
GPVI-mediated activation cascade R-HSA-114604
CD28 co-stimulation R-HSA-389356
Intracellular signaling by second messengers R-HSA-9006925
Platelet activation, signaling and aggregation R-HSA-76002
FLT3 signaling through SRC family kinases R-HSA-9706374
Interleukin-2 signaling R-HSA-9020558
Immune System R-HSA-168256
CD28 dependent PI3K/Akt signaling R-HSA-389357
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952
Host Interactions of HIV factors R-HSA-162909
RHOH GTPase cycle R-HSA-9013407
TCR signaling R-HSA-202403
Costimulation by the CD28 family R-HSA-388841
Signaling by KIT in disease R-HSA-9669938
DAP12 interactions R-HSA-2172127
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Cytokine Signaling in Immune system R-HSA-1280215
Nef and signal transduction R-HSA-164944
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427
RHO GTPase cycle R-HSA-9012999
Interleukin-2 family signaling R-HSA-451927
Nef Mediated CD4 Down-regulation R-HSA-167590
Signaling by Rho GTPases R-HSA-194315
Translocation of ZAP-70 to Immunological synapse R-HSA-202430
HIV Infection R-HSA-162906
Signal Transduction R-HSA-162582
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
PD-1 signaling R-HSA-389948
PIP3 activates AKT signaling R-HSA-1257604
Regulation of KIT signaling R-HSA-1433559
Hemostasis R-HSA-109582
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Downstream TCR signaling R-HSA-202424
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
CD28 dependent Vav1 pathway R-HSA-389359
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by SCF-KIT R-HSA-1433557
FLT3 Signaling R-HSA-9607240
DAP12 signaling R-HSA-2424491
CTLA4 inhibitory signaling R-HSA-389513
PECAM1 interactions R-HSA-210990
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938
RHO GTPase cycle R-HSA-9012999
Nef Mediated CD4 Down-regulation R-HSA-167590
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Infectious disease R-HSA-5663205
Signaling by SCF-KIT R-HSA-1433557
PIP3 activates AKT signaling R-HSA-1257604
Immune System R-HSA-168256
Signaling by Rho GTPases R-HSA-194315
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Negative regulation of the PI3K/AKT network R-HSA-199418
PECAM1 interactions R-HSA-210990
FLT3 Signaling R-HSA-9607240
Intracellular signaling by second messengers R-HSA-9006925
Costimulation by the CD28 family R-HSA-388841
PD-1 signaling R-HSA-389948
Generation of second messenger molecules R-HSA-202433
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Translocation of ZAP-70 to Immunological synapse R-HSA-202430
RHOH GTPase cycle R-HSA-9013407
Adaptive Immune System R-HSA-1280218
Signaling by KIT in disease R-HSA-9669938
TCR signaling R-HSA-202403
DAP12 signaling R-HSA-2424491
Interleukin-2 family signaling R-HSA-451927
Innate Immune System R-HSA-168249
GPVI-mediated activation cascade R-HSA-114604
Signal Transduction R-HSA-162582
Downstream TCR signaling R-HSA-202424
CD28 dependent Vav1 pathway R-HSA-389359
Interleukin-2 signaling R-HSA-9020558
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Platelet activation, signaling and aggregation R-HSA-76002
CD28 dependent PI3K/Akt signaling R-HSA-389357
CD28 co-stimulation R-HSA-389356
Hemostasis R-HSA-109582
Host Interactions of HIV factors R-HSA-162909
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Cell surface interactions at the vascular wall R-HSA-202733
Disease R-HSA-1643685
Signaling by Interleukins R-HSA-449147
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952
Regulation of KIT signaling R-HSA-1433559
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427
HIV Infection R-HSA-162906
Nef and signal transduction R-HSA-164944
FLT3 signaling through SRC family kinases R-HSA-9706374
CTLA4 inhibitory signaling R-HSA-389513
DAP12 interactions R-HSA-2172127
CTLA4 inhibitory signaling R-HSA-389513
CD28 dependent Vav1 pathway R-HSA-389359
Host Interactions of HIV factors R-HSA-162909
GPVI-mediated activation cascade R-HSA-114604
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
DAP12 interactions R-HSA-2172127
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by KIT in disease R-HSA-9669938
Nef Mediated CD4 Down-regulation R-HSA-167590
Hemostasis R-HSA-109582
RHOH GTPase cycle R-HSA-9013407
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952
Signal Transduction R-HSA-162582
DAP12 signaling R-HSA-2424491
Interleukin-2 family signaling R-HSA-451927
Intracellular signaling by second messengers R-HSA-9006925
PECAM1 interactions R-HSA-210990
PD-1 signaling R-HSA-389948
Interleukin-2 signaling R-HSA-9020558
Generation of second messenger molecules R-HSA-202433
FLT3 Signaling R-HSA-9607240
RHO GTPase cycle R-HSA-9012999
Adaptive Immune System R-HSA-1280218
Nef and signal transduction R-HSA-164944
CD28 dependent PI3K/Akt signaling R-HSA-389357
Regulation of KIT signaling R-HSA-1433559
HIV Infection R-HSA-162906
Translocation of ZAP-70 to Immunological synapse R-HSA-202430
PI3K/AKT Signaling in Cancer R-HSA-2219528
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
Cell surface interactions at the vascular wall R-HSA-202733
Innate Immune System R-HSA-168249
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Downstream TCR signaling R-HSA-202424
Signaling by SCF-KIT R-HSA-1433557
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Costimulation by the CD28 family R-HSA-388841
Immune System R-HSA-168256
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Interleukins R-HSA-449147
FLT3 signaling through SRC family kinases R-HSA-9706374
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427
Disease R-HSA-1643685
Signaling by Rho GTPases R-HSA-194315
CD28 co-stimulation R-HSA-389356
Hemostasis R-HSA-109582
Interleukin-2 signaling R-HSA-9020558
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nef and signal transduction R-HSA-164944
CD28 co-stimulation R-HSA-389356
PIP3 activates AKT signaling R-HSA-1257604
PI3K/AKT Signaling in Cancer R-HSA-2219528
Adaptive Immune System R-HSA-1280218
FLT3 signaling through SRC family kinases R-HSA-9706374
Signaling by SCF-KIT R-HSA-1433557
CTLA4 inhibitory signaling R-HSA-389513
Cell surface interactions at the vascular wall R-HSA-202733
HIV Infection R-HSA-162906
Platelet activation, signaling and aggregation R-HSA-76002
RHO GTPase cycle R-HSA-9012999
Costimulation by the CD28 family R-HSA-388841
Signaling by Interleukins R-HSA-449147
RHOH GTPase cycle R-HSA-9013407
GPVI-mediated activation cascade R-HSA-114604
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427
Immune System R-HSA-168256
CD28 dependent Vav1 pathway R-HSA-389359
Negative regulation of the PI3K/AKT network R-HSA-199418
DAP12 signaling R-HSA-2424491
PECAM1 interactions R-HSA-210990
Translocation of ZAP-70 to Immunological synapse R-HSA-202430
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Downstream TCR signaling R-HSA-202424
Generation of second messenger molecules R-HSA-202433
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
TCR signaling R-HSA-202403
Regulation of KIT signaling R-HSA-1433559
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
Signaling by KIT in disease R-HSA-9669938
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
FLT3 Signaling R-HSA-9607240
Signaling by Rho GTPases R-HSA-194315
Host Interactions of HIV factors R-HSA-162909
Infectious disease R-HSA-5663205
Interleukin-2 family signaling R-HSA-451927
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952
Nef Mediated CD4 Down-regulation R-HSA-167590
PD-1 signaling R-HSA-389948
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938
Innate Immune System R-HSA-168249
DAP12 interactions R-HSA-2172127
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
CD28 dependent Vav1 pathway R-HSA-389359
DAP12 interactions R-HSA-2172127
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952
Infectious disease R-HSA-5663205
Host Interactions of HIV factors R-HSA-162909
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase cycle R-HSA-9012999
Interleukin-2 family signaling R-HSA-451927
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Nef and signal transduction R-HSA-164944
Cell surface interactions at the vascular wall R-HSA-202733
Nef Mediated CD4 Down-regulation R-HSA-167590
PD-1 signaling R-HSA-389948
Signaling by SCF-KIT R-HSA-1433557
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Signaling by KIT in disease R-HSA-9669938
GPVI-mediated activation cascade R-HSA-114604
HIV Infection R-HSA-162906
RHOH GTPase cycle R-HSA-9013407
Adaptive Immune System R-HSA-1280218
Downstream TCR signaling R-HSA-202424
PIP3 activates AKT signaling R-HSA-1257604
Regulation of KIT signaling R-HSA-1433559
FLT3 signaling through SRC family kinases R-HSA-9706374
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427
PI3K/AKT Signaling in Cancer R-HSA-2219528
FLT3 Signaling R-HSA-9607240
Translocation of ZAP-70 to Immunological synapse R-HSA-202430
Costimulation by the CD28 family R-HSA-388841
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Signaling by Interleukins R-HSA-449147
Signaling by Rho GTPases R-HSA-194315
Interleukin-2 signaling R-HSA-9020558
CTLA4 inhibitory signaling R-HSA-389513
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
CD28 dependent PI3K/Akt signaling R-HSA-389357
TCR signaling R-HSA-202403
Signal Transduction R-HSA-162582
PECAM1 interactions R-HSA-210990
Generation of second messenger molecules R-HSA-202433
Cytokine Signaling in Immune system R-HSA-1280215
DAP12 signaling R-HSA-2424491
CD28 co-stimulation R-HSA-389356
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nef Mediated CD4 Down-regulation R-HSA-167590
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Cytokine Signaling in Immune system R-HSA-1280215
DAP12 interactions R-HSA-2172127
Nef and signal transduction R-HSA-164944
Negative regulation of the PI3K/AKT network R-HSA-199418
Translocation of ZAP-70 to Immunological synapse R-HSA-202430
CD28 dependent PI3K/Akt signaling R-HSA-389357
GPVI-mediated activation cascade R-HSA-114604
RHO GTPase cycle R-HSA-9012999
DAP12 signaling R-HSA-2424491
TCR signaling R-HSA-202403
Signaling by Interleukins R-HSA-449147
FLT3 Signaling R-HSA-9607240
Cell surface interactions at the vascular wall R-HSA-202733
FLT3 signaling through SRC family kinases R-HSA-9706374
Adaptive Immune System R-HSA-1280218
Hemostasis R-HSA-109582
Signaling by Rho GTPases R-HSA-194315
Interleukin-2 family signaling R-HSA-451927
CD28 dependent Vav1 pathway R-HSA-389359
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
HIV Infection R-HSA-162906
Signaling by KIT in disease R-HSA-9669938
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
PI3K/AKT Signaling in Cancer R-HSA-2219528
Interleukin-2 signaling R-HSA-9020558
PD-1 signaling R-HSA-389948
Generation of second messenger molecules R-HSA-202433
CD28 co-stimulation R-HSA-389356
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427
PECAM1 interactions R-HSA-210990
RHOH GTPase cycle R-HSA-9013407
Downstream TCR signaling R-HSA-202424
Host Interactions of HIV factors R-HSA-162909
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Signaling by SCF-KIT R-HSA-1433557
Disease R-HSA-1643685
Costimulation by the CD28 family R-HSA-388841
CTLA4 inhibitory signaling R-HSA-389513
Immune System R-HSA-168256
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of KIT signaling R-HSA-1433559
DAP12 interactions R-HSA-2172127
Costimulation by the CD28 family R-HSA-388841
Cell surface interactions at the vascular wall R-HSA-202733
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952
RHO GTPase cycle R-HSA-9012999
CTLA4 inhibitory signaling R-HSA-389513
Translocation of ZAP-70 to Immunological synapse R-HSA-202430
Nef and signal transduction R-HSA-164944
Signaling by KIT in disease R-HSA-9669938
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases R-HSA-194315
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
PD-1 signaling R-HSA-389948
Platelet activation, signaling and aggregation R-HSA-76002
Immune System R-HSA-168256
Signaling by SCF-KIT R-HSA-1433557
TCR signaling R-HSA-202403
Adaptive Immune System R-HSA-1280218
Regulation of KIT signaling R-HSA-1433559
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
Interleukin-2 signaling R-HSA-9020558
Signal Transduction R-HSA-162582
HIV Infection R-HSA-162906
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Hemostasis R-HSA-109582
Generation of second messenger molecules R-HSA-202433
Intracellular signaling by second messengers R-HSA-9006925
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938
Interleukin-2 family signaling R-HSA-451927
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
CD28 dependent Vav1 pathway R-HSA-389359
RHOH GTPase cycle R-HSA-9013407
Innate Immune System R-HSA-168249
FLT3 Signaling R-HSA-9607240
FLT3 signaling through SRC family kinases R-HSA-9706374
GPVI-mediated activation cascade R-HSA-114604
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Downstream TCR signaling R-HSA-202424
Nef Mediated CD4 Down-regulation R-HSA-167590
Host Interactions of HIV factors R-HSA-162909
CD28 co-stimulation R-HSA-389356
DAP12 signaling R-HSA-2424491
PECAM1 interactions R-HSA-210990
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream TCR signaling R-HSA-202424
GPVI-mediated activation cascade R-HSA-114604
Negative regulation of the PI3K/AKT network R-HSA-199418
Translocation of ZAP-70 to Immunological synapse R-HSA-202430
Signaling by SCF-KIT R-HSA-1433557
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
Hemostasis R-HSA-109582
Infectious disease R-HSA-5663205
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Generation of second messenger molecules R-HSA-202433
CD28 dependent Vav1 pathway R-HSA-389359
Interleukin-2 family signaling R-HSA-451927
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by KIT in disease R-HSA-9669938
Cytokine Signaling in Immune system R-HSA-1280215
PI3K/AKT Signaling in Cancer R-HSA-2219528
DAP12 interactions R-HSA-2172127
Intracellular signaling by second messengers R-HSA-9006925
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Immune System R-HSA-168256
FLT3 signaling through SRC family kinases R-HSA-9706374
Interleukin-2 signaling R-HSA-9020558
CTLA4 inhibitory signaling R-HSA-389513
PECAM1 interactions R-HSA-210990
PIP3 activates AKT signaling R-HSA-1257604
Host Interactions of HIV factors R-HSA-162909
Adaptive Immune System R-HSA-1280218
CD28 co-stimulation R-HSA-389356
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cell surface interactions at the vascular wall R-HSA-202733
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
HIV Infection R-HSA-162906
Signaling by Rho GTPases R-HSA-194315
Nef and signal transduction R-HSA-164944
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Interleukins R-HSA-449147
Costimulation by the CD28 family R-HSA-388841
Disease R-HSA-1643685
CD28 dependent PI3K/Akt signaling R-HSA-389357
Nef Mediated CD4 Down-regulation R-HSA-167590
FLT3 Signaling R-HSA-9607240
Regulation of KIT signaling R-HSA-1433559
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952
RHO GTPase cycle R-HSA-9012999
PD-1 signaling R-HSA-389948
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHOH GTPase cycle R-HSA-9013407
TCR signaling R-HSA-202403
DAP12 signaling R-HSA-2424491

Expression Atlas ENSG00000182866
LRG display in Ensembl gene LRG_153
NCBI gene (formerly Entrezgene) 3932
GeneCards 6524
HGNC Symbol HGNC:6524
MIM gene 153390
MIM morbid 615758
UniProtKB Gene Name P06239
WikiGene 3932
Ensembl ID : ENSG00000089022
Description: MAPK activated protein kinase 5
Gene Synonyms: MK5,PRAK
1 APIs:
179 Possible Orthologues:

Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Oxidative Stress Induced Senescence R-HSA-2559580
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
MAPK family signaling cascades R-HSA-5683057
Cellular Senescence R-HSA-2559583
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity R-HSA-5633007
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK6/MAPK4 signaling R-HSA-5687128
MAPK6/MAPK4 signaling R-HSA-5687128
Oxidative Stress Induced Senescence R-HSA-2559580
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity R-HSA-5633007
Regulation of TP53 Activity R-HSA-5633007
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stress R-HSA-2262752
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Cellular Senescence R-HSA-2559583
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity R-HSA-5633007
Oxidative Stress Induced Senescence R-HSA-2559580
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
MAPK family signaling cascades R-HSA-5683057
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Cellular Senescence R-HSA-2559583
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of TP53 Activity R-HSA-5633007
MAPK family signaling cascades R-HSA-5683057
Transcriptional Regulation by TP53 R-HSA-3700989
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
MAPK6/MAPK4 signaling R-HSA-5687128
Oxidative Stress Induced Senescence R-HSA-2559580
Transcriptional Regulation by TP53 R-HSA-3700989
MAPK family signaling cascades R-HSA-5683057
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
Oxidative Stress Induced Senescence R-HSA-2559580
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of TP53 Activity R-HSA-5633007
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Oxidative Stress Induced Senescence R-HSA-2559580
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stimuli R-HSA-8953897
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Regulation of TP53 Activity R-HSA-5633007
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583

Expression Atlas ENSG00000089022
NCBI gene (formerly Entrezgene) 8550
GeneCards 6889
HGNC Symbol HGNC:6889
MIM gene 606723
MIM morbid 619869
UniProtKB Gene Name R4GN93
WikiGene 8550
Gene: PRKCG
Ensembl ID : ENSG00000126583
Description: protein kinase C gamma
Gene Synonyms: MGC57564,PKCC,PKCG,SCA14
5 APIs:
200 Possible Orthologues:

G alpha (i) signalling events R-HSA-418594
DAG and IP3 signaling R-HSA-1489509
Transmission across Chemical Synapses R-HSA-112315
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
PLC beta mediated events R-HSA-112043
G alpha (z) signalling events R-HSA-418597
Beta-catenin independent WNT signaling R-HSA-3858494
CaM pathway R-HSA-111997
Signaling by WNT R-HSA-195721
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Trafficking of AMPA receptors R-HSA-399719
Intracellular signaling by second messengers R-HSA-9006925
Neuronal System R-HSA-112316
Platelet activation, signaling and aggregation R-HSA-76002
Disinhibition of SNARE formation R-HSA-114516
PCP/CE pathway R-HSA-4086400
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Calmodulin induced events R-HSA-111933
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Opioid Signalling R-HSA-111885
Ca-dependent events R-HSA-111996
Signal Transduction R-HSA-162582
WNT5A-dependent internalization of FZD4 R-HSA-5099900
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
PLC beta mediated events R-HSA-112043
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Opioid Signalling R-HSA-111885
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
GPCR downstream signalling R-HSA-388396
PCP/CE pathway R-HSA-4086400
G-protein mediated events R-HSA-112040
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
G alpha (i) signalling events R-HSA-418594
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (z) signalling events R-HSA-418597
Signaling by WNT R-HSA-195721
Calmodulin induced events R-HSA-111933
Intracellular signaling by second messengers R-HSA-9006925
Ca-dependent events R-HSA-111996
Signal Transduction R-HSA-162582
Trafficking of AMPA receptors R-HSA-399719
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by GPCR R-HSA-372790
CaM pathway R-HSA-111997
Disinhibition of SNARE formation R-HSA-114516
DAG and IP3 signaling R-HSA-1489509
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
G alpha (i) signalling events R-HSA-418594
PCP/CE pathway R-HSA-4086400
PLC beta mediated events R-HSA-112043
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Signaling by WNT R-HSA-195721
Ca-dependent events R-HSA-111996
DAG and IP3 signaling R-HSA-1489509
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
Intracellular signaling by second messengers R-HSA-9006925
WNT5A-dependent internalization of FZD4 R-HSA-5099900
G alpha (z) signalling events R-HSA-418597
Opioid Signalling R-HSA-111885
Beta-catenin independent WNT signaling R-HSA-3858494
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Calmodulin induced events R-HSA-111933
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Disinhibition of SNARE formation R-HSA-114516
CaM pathway R-HSA-111997
Trafficking of AMPA receptors R-HSA-399719
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Neuronal System R-HSA-112316
Beta-catenin independent WNT signaling R-HSA-3858494
DAG and IP3 signaling R-HSA-1489509
Calmodulin induced events R-HSA-111933
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Intracellular signaling by second messengers R-HSA-9006925
Trafficking of AMPA receptors R-HSA-399719
Signal Transduction R-HSA-162582
Ca-dependent events R-HSA-111996
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by WNT R-HSA-195721
G-protein mediated events R-HSA-112040
Signaling by GPCR R-HSA-372790
PCP/CE pathway R-HSA-4086400
PLC beta mediated events R-HSA-112043
G alpha (i) signalling events R-HSA-418594
G alpha (z) signalling events R-HSA-418597
GPCR downstream signalling R-HSA-388396
Opioid Signalling R-HSA-111885
Transmission across Chemical Synapses R-HSA-112315
CaM pathway R-HSA-111997
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Disinhibition of SNARE formation R-HSA-114516
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
DAG and IP3 signaling R-HSA-1489509
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signaling by WNT R-HSA-195721
PLC beta mediated events R-HSA-112043
Intracellular signaling by second messengers R-HSA-9006925
G-protein mediated events R-HSA-112040
PCP/CE pathway R-HSA-4086400
Neuronal System R-HSA-112316
Signal Transduction R-HSA-162582
Ca-dependent events R-HSA-111996
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Calmodulin induced events R-HSA-111933
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Disinhibition of SNARE formation R-HSA-114516
G alpha (z) signalling events R-HSA-418597
CaM pathway R-HSA-111997
Transmission across Chemical Synapses R-HSA-112315
Signaling by GPCR R-HSA-372790
Beta-catenin independent WNT signaling R-HSA-3858494
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Platelet activation, signaling and aggregation R-HSA-76002
Trafficking of AMPA receptors R-HSA-399719
Opioid Signalling R-HSA-111885
Beta-catenin independent WNT signaling R-HSA-3858494
G alpha (i) signalling events R-HSA-418594
Hemostasis R-HSA-109582
WNT5A-dependent internalization of FZD4 R-HSA-5099900
G-protein mediated events R-HSA-112040
Trafficking of AMPA receptors R-HSA-399719
PCP/CE pathway R-HSA-4086400
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Calmodulin induced events R-HSA-111933
GPCR downstream signalling R-HSA-388396
Disinhibition of SNARE formation R-HSA-114516
DAG and IP3 signaling R-HSA-1489509
Transmission across Chemical Synapses R-HSA-112315
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neuronal System R-HSA-112316
Ca-dependent events R-HSA-111996
G alpha (z) signalling events R-HSA-418597
Opioid Signalling R-HSA-111885
PLC beta mediated events R-HSA-112043
Intracellular signaling by second messengers R-HSA-9006925
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Signaling by WNT R-HSA-195721
Platelet activation, signaling and aggregation R-HSA-76002
CaM pathway R-HSA-111997
Signaling by GPCR R-HSA-372790
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signal Transduction R-HSA-162582
Beta-catenin independent WNT signaling R-HSA-3858494
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
GPCR downstream signalling R-HSA-388396
DAG and IP3 signaling R-HSA-1489509
Trafficking of AMPA receptors R-HSA-399719
Ca-dependent events R-HSA-111996
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signaling by GPCR R-HSA-372790
CaM pathway R-HSA-111997
Signaling by WNT R-HSA-195721
Calmodulin induced events R-HSA-111933
PLC beta mediated events R-HSA-112043
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neuronal System R-HSA-112316
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
Platelet activation, signaling and aggregation R-HSA-76002
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Transmission across Chemical Synapses R-HSA-112315
Opioid Signalling R-HSA-111885
Disinhibition of SNARE formation R-HSA-114516
G alpha (z) signalling events R-HSA-418597
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Hemostasis R-HSA-109582
CaM pathway R-HSA-111997
Trafficking of AMPA receptors R-HSA-399719
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Transmission across Chemical Synapses R-HSA-112315
Signaling by WNT R-HSA-195721
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Disinhibition of SNARE formation R-HSA-114516
G alpha (z) signalling events R-HSA-418597
DAG and IP3 signaling R-HSA-1489509
Platelet activation, signaling and aggregation R-HSA-76002
Neuronal System R-HSA-112316
Calmodulin induced events R-HSA-111933
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Opioid Signalling R-HSA-111885
Ca-dependent events R-HSA-111996
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
PLC beta mediated events R-HSA-112043
G-protein mediated events R-HSA-112040
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
CaM pathway R-HSA-111997
PLC beta mediated events R-HSA-112043
Beta-catenin independent WNT signaling R-HSA-3858494
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Opioid Signalling R-HSA-111885
Intracellular signaling by second messengers R-HSA-9006925
Trafficking of AMPA receptors R-HSA-399719
G alpha (i) signalling events R-HSA-418594
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
G-protein mediated events R-HSA-112040
Disinhibition of SNARE formation R-HSA-114516
PCP/CE pathway R-HSA-4086400
Neuronal System R-HSA-112316
Hemostasis R-HSA-109582
GPCR downstream signalling R-HSA-388396
Transmission across Chemical Synapses R-HSA-112315
Signaling by GPCR R-HSA-372790
Ca-dependent events R-HSA-111996
G alpha (z) signalling events R-HSA-418597
DAG and IP3 signaling R-HSA-1489509
Signaling by WNT R-HSA-195721
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Calmodulin induced events R-HSA-111933
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Disinhibition of SNARE formation R-HSA-114516
Opioid Signalling R-HSA-111885
Signal Transduction R-HSA-162582
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Beta-catenin independent WNT signaling R-HSA-3858494
Intracellular signaling by second messengers R-HSA-9006925
Ca-dependent events R-HSA-111996
Calmodulin induced events R-HSA-111933
Signaling by GPCR R-HSA-372790
G-protein mediated events R-HSA-112040
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
DAG and IP3 signaling R-HSA-1489509
Neuronal System R-HSA-112316
G alpha (z) signalling events R-HSA-418597
PCP/CE pathway R-HSA-4086400
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Platelet activation, signaling and aggregation R-HSA-76002
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by WNT R-HSA-195721
CaM pathway R-HSA-111997
G alpha (i) signalling events R-HSA-418594
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
PLC beta mediated events R-HSA-112043
Trafficking of AMPA receptors R-HSA-399719
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Transmission across Chemical Synapses R-HSA-112315

Expression Atlas ENSG00000126583
LRG display in Ensembl gene LRG_669
NCBI gene (formerly Entrezgene) 5582
GeneCards 9402
HGNC Symbol HGNC:9402
MIM gene 176980
MIM morbid 605361
UniProtKB Gene Name P05129
WikiGene 5582
Gene: EML4
Ensembl ID : ENSG00000143924
Description: EMAP like 4
Gene Synonyms: C2ORF2,ELP120,ROPP120
5 APIs:
214 Possible Orthologues:

ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK in cancer R-HSA-9700206
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Mitotic Prometaphase R-HSA-68877
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
ALK mutants bind TKIs R-HSA-9700645
Disease R-HSA-1643685
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK fusions and activated point mutants R-HSA-9725370
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Cell Cycle R-HSA-1640170
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
M Phase R-HSA-68886
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Cell Cycle, Mitotic R-HSA-69278
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Mitotic Prometaphase R-HSA-68877
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
ALK mutants bind TKIs R-HSA-9700645
M Phase R-HSA-68886
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK in cancer R-HSA-9700206
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Cell Cycle, Mitotic R-HSA-69278
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
ALK mutants bind TKIs R-HSA-9700645
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Mitotic Prometaphase R-HSA-68877
Cell Cycle, Mitotic R-HSA-69278
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
ALK mutants bind TKIs R-HSA-9700645
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by ALK in cancer R-HSA-9700206
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Signaling by ALK in cancer R-HSA-9700206
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Disease R-HSA-1643685
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Cell Cycle R-HSA-1640170
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
M Phase R-HSA-68886

Expression Atlas ENSG00000143924
NCBI gene (formerly Entrezgene) 27436
GeneCards 1316
HGNC Symbol HGNC:1316
MIM gene 607442
UniProtKB Gene Name Q9HC35
WikiGene 27436
Gene: FLT4
Ensembl ID : ENSG00000037280
Description: fms related receptor tyrosine kinase 4
Gene Synonyms: PCL,VEGFR-3,VEGFR3
46 APIs:
198 Possible Orthologues:

Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by NOTCH4 R-HSA-9013694
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH R-HSA-157118
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by VEGF R-HSA-194138
Signaling by NOTCH R-HSA-157118
Signaling by VEGF R-HSA-194138
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signal Transduction R-HSA-162582
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by NOTCH4 R-HSA-9013694
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by VEGF R-HSA-194138
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
Signaling by VEGF R-HSA-194138
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH R-HSA-157118
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by NOTCH4 R-HSA-9013694
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH R-HSA-157118
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by VEGF R-HSA-194138
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by VEGF R-HSA-194138
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694

Expression Atlas ENSG00000037280
NCBI gene (formerly Entrezgene) 2324
GeneCards 3767
HGNC Symbol HGNC:3767
MIM gene 136352
MIM morbid 618780
UniProtKB Gene Name P35916
WikiGene 2324
Gene: FRK
Ensembl ID : ENSG00000111816
Description: fyn related Src family tyrosine kinase
Gene Synonyms: GTK,PTK5,RAK
1 APIs:
217 Possible Orthologues:

Intracellular signaling by second messengers R-HSA-9006925
Immune System R-HSA-168256
PTEN Regulation R-HSA-6807070
Neutrophil degranulation R-HSA-6798695
PIP3 activates AKT signaling R-HSA-1257604
Regulation of PTEN stability and activity R-HSA-8948751
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
PTEN Regulation R-HSA-6807070
Neutrophil degranulation R-HSA-6798695
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Regulation of PTEN stability and activity R-HSA-8948751
Innate Immune System R-HSA-168249
Regulation of PTEN stability and activity R-HSA-8948751
Neutrophil degranulation R-HSA-6798695
PTEN Regulation R-HSA-6807070
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Innate Immune System R-HSA-168249
PIP3 activates AKT signaling R-HSA-1257604
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
Neutrophil degranulation R-HSA-6798695
PIP3 activates AKT signaling R-HSA-1257604
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
PTEN Regulation R-HSA-6807070
Intracellular signaling by second messengers R-HSA-9006925
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Neutrophil degranulation R-HSA-6798695
Regulation of PTEN stability and activity R-HSA-8948751
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
PIP3 activates AKT signaling R-HSA-1257604
Regulation of PTEN stability and activity R-HSA-8948751
PTEN Regulation R-HSA-6807070
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Regulation of PTEN stability and activity R-HSA-8948751
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
PTEN Regulation R-HSA-6807070
Regulation of PTEN stability and activity R-HSA-8948751
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Innate Immune System R-HSA-168249
PTEN Regulation R-HSA-6807070
Neutrophil degranulation R-HSA-6798695
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
PIP3 activates AKT signaling R-HSA-1257604

Expression Atlas ENSG00000111816
NCBI gene (formerly Entrezgene) 2444
GeneCards 3955
HGNC Symbol HGNC:3955
MIM gene 606573
UniProtKB Gene Name P42685
WikiGene 2444
Gene: AXL
Ensembl ID : ENSG00000167601
Description: AXL receptor tyrosine kinase
Gene Synonyms: ARK,JTK11,TYRO7,UFO
5 APIs:
198 Possible Orthologues:

Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
VEGFA-VEGFR2 Pathway R-HSA-4420097
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000167601
NCBI gene (formerly Entrezgene) 558
GeneCards 905
HGNC Symbol HGNC:905
MIM gene 109135
MIM morbid 146110
UniProtKB Gene Name P30530
WikiGene 558