Gene: MAPK3
Ensembl ID : ENSG00000102882
Description: mitogen-activated protein kinase 3
Gene Synonyms: ERK1,P44ERK1,P44MAPK,PRKM3
6 APIs:
199 Possible Orthologues:

ERK/MAPK targets R-HSA-198753
M Phase R-HSA-68886
Disease R-HSA-1643685
Signaling by RAS mutants R-HSA-6802949
Signaling by NODAL R-HSA-1181150
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
G alpha (q) signalling events R-HSA-416476
ESR-mediated signaling R-HSA-8939211
Signal attenuation R-HSA-74749
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Growth hormone receptor signaling R-HSA-982772
GPCR downstream signalling R-HSA-388396
Negative regulation of MAPK pathway R-HSA-5675221
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR3 R-HSA-5654741
Signaling by TGF-beta Receptor Complex R-HSA-170834
ISG15 antiviral mechanism R-HSA-1169408
RUNX2 regulates bone development R-HSA-8941326
Toll-like Receptor Cascades R-HSA-168898
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Negative regulation of FGFR3 signaling R-HSA-5654732
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Disease R-HSA-1643685
Signaling by Nuclear Receptors R-HSA-9006931
Activation of the AP-1 family of transcription factors R-HSA-450341
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by FGFR1 R-HSA-5654736
Signaling by Activin R-HSA-1502540
Signaling by NTRKs R-HSA-166520
L1CAM interactions R-HSA-373760
MAPK3 (ERK1) activation R-HSA-110056
Interferon Signaling R-HSA-913531
Frs2-mediated activation R-HSA-170968
Signalling to ERKs R-HSA-187687
RNA Polymerase I Promoter Opening R-HSA-73728
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ALK in cancer R-HSA-9700206
Cell Cycle, Mitotic R-HSA-69278
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
NCAM signaling for neurite out-growth R-HSA-375165
Cellular responses to stress R-HSA-2262752
Signaling downstream of RAS mutants R-HSA-9649948
Negative regulation of the PI3K/AKT network R-HSA-199418
MyD88 cascade initiated on plasma membrane R-HSA-975871
Formation of apoptosome R-HSA-111458
ERK/MAPK targets R-HSA-198753
Response of Mtb to phagocytosis R-HSA-9637690
M Phase R-HSA-68886
Post NMDA receptor activation events R-HSA-438064
Transcriptional regulation by RUNX2 R-HSA-8878166
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Suppression of apoptosis R-HSA-9635465
Cellular Senescence R-HSA-2559583
Nervous system development R-HSA-9675108
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Hemostasis R-HSA-109582
Intrinsic Pathway for Apoptosis R-HSA-109606
RNA Polymerase I Promoter Clearance R-HSA-73854
Regulation of the apoptosome activity R-HSA-9627069
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-17 signaling R-HSA-448424
Innate Immune System R-HSA-168249
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Neuronal System R-HSA-112316
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF-independent MAPK1/3 activation R-HSA-112409
Leishmania phagocytosis R-HSA-9664417
MAPK family signaling cascades R-HSA-5683057
Generic Transcription Pathway R-HSA-212436
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Immune System R-HSA-168256
Signaling by TGFB family members R-HSA-9006936
Signal transduction by L1 R-HSA-445144
Signaling by FGFR4 R-HSA-5654743
Oxidative Stress Induced Senescence R-HSA-2559580
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Cytochrome c-mediated apoptotic response R-HSA-111461
MAP kinase activation R-HSA-450294
Insulin receptor signalling cascade R-HSA-74751
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Insulin receptor R-HSA-74752
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RNA Polymerase I Transcription R-HSA-73864
MyD88-independent TLR4 cascade R-HSA-166166
Transmission across Chemical Synapses R-HSA-112315
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by Interleukins R-HSA-449147
Signaling by FGFR2 R-HSA-5654738
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Leishmania infection R-HSA-9658195
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Apoptotic factor-mediated response R-HSA-111471
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by GPCR R-HSA-372790
RHO GTPase Effectors R-HSA-195258
Oncogene Induced Senescence R-HSA-2559585
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
PTEN Regulation R-HSA-6807070
Developmental Biology R-HSA-1266738
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Cellular response to heat stress R-HSA-3371556
NPAS4 regulates expression of target genes R-HSA-9768919
ERKs are inactivated R-HSA-202670
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Programmed Cell Death R-HSA-5357801
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MAP2K and MAPK activation R-HSA-5674135
RAF/MAP kinase cascade R-HSA-5673001
FCGR3A-mediated phagocytosis R-HSA-9664422
Negative regulation of FGFR1 signaling R-HSA-5654726
Parasite infection R-HSA-9664407
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
Signaling by MAP2K mutants R-HSA-9652169
Axon guidance R-HSA-422475
Infection with Mycobacterium tuberculosis R-HSA-9635486
Oncogenic MAPK signaling R-HSA-6802957
Apoptosis R-HSA-109581
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cell Cycle R-HSA-1640170
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Prolonged ERK activation events R-HSA-169893
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Negative regulation of FGFR4 signaling R-HSA-5654733
FCERI mediated MAPK activation R-HSA-2871796
Infectious disease R-HSA-5663205
Negative regulation of FGFR2 signaling R-HSA-5654727
Mitotic Prophase R-HSA-68875
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Signaling by FGFR R-HSA-190236
Transcriptional Regulation by NPAS4 R-HSA-9634815
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by NTRK1 (TRKA) R-HSA-187037
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
RSK activation R-HSA-444257
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Frs2-mediated activation R-HSA-170968
Cell Cycle, Mitotic R-HSA-69278
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by RAS mutants R-HSA-6802949
Interleukin-17 signaling R-HSA-448424
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Signaling by GPCR R-HSA-372790
Growth hormone receptor signaling R-HSA-982772
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by FGFR3 R-HSA-5654741
Suppression of apoptosis R-HSA-9635465
Transcriptional regulation by RUNX2 R-HSA-8878166
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
M Phase R-HSA-68886
Cellular response to heat stress R-HSA-3371556
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RSK activation R-HSA-444257
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by TGFB family members R-HSA-9006936
Signal transduction by L1 R-HSA-445144
FCGR3A-mediated phagocytosis R-HSA-9664422
Response of Mtb to phagocytosis R-HSA-9637690
Regulation of PTEN gene transcription R-HSA-8943724
Negative feedback regulation of MAPK pathway R-HSA-5674499
MAP2K and MAPK activation R-HSA-5674135
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Rho GTPases R-HSA-194315
Signaling by Insulin receptor R-HSA-74752
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Axon guidance R-HSA-422475
Programmed Cell Death R-HSA-5357801
NPAS4 regulates expression of target genes R-HSA-9768919
Neuronal System R-HSA-112316
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Hemostasis R-HSA-109582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Immune System R-HSA-168256
Cytochrome c-mediated apoptotic response R-HSA-111461
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal attenuation R-HSA-74749
Formation of apoptosome R-HSA-111458
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by ALK in cancer R-HSA-9700206
Signaling by Nuclear Receptors R-HSA-9006931
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cellular Senescence R-HSA-2559583
Signaling by MAP2K mutants R-HSA-9652169
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Transmission across Chemical Synapses R-HSA-112315
Signaling by FGFR R-HSA-190236
FCERI mediated MAPK activation R-HSA-2871796
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Cellular responses to stress R-HSA-2262752
Signaling by FGFR2 R-HSA-5654738
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
ERK/MAPK targets R-HSA-198753
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by NTRKs R-HSA-166520
Transcriptional Regulation by NPAS4 R-HSA-9634815
GPCR downstream signalling R-HSA-388396
MyD88-independent TLR4 cascade R-HSA-166166
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
PTEN Regulation R-HSA-6807070
Cell Cycle R-HSA-1640170
Negative regulation of FGFR1 signaling R-HSA-5654726
L1CAM interactions R-HSA-373760
Negative regulation of FGFR3 signaling R-HSA-5654732
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signalling to ERKs R-HSA-187687
Post NMDA receptor activation events R-HSA-438064
Oncogenic MAPK signaling R-HSA-6802957
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Interferon Signaling R-HSA-913531
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
RNA Polymerase I Promoter Opening R-HSA-73728
Activation of the AP-1 family of transcription factors R-HSA-450341
RNA Polymerase I Promoter Clearance R-HSA-73854
ERKs are inactivated R-HSA-202670
MyD88 dependent cascade initiated on endosome R-HSA-975155
ESR-mediated signaling R-HSA-8939211
Negative regulation of FGFR4 signaling R-HSA-5654733
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Activin R-HSA-1502540
Signaling by NTRK1 (TRKA) R-HSA-187037
Gene expression (Transcription) R-HSA-74160
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Negative regulation of FGFR2 signaling R-HSA-5654727
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK family signaling cascades R-HSA-5683057
Signaling by Interleukins R-HSA-449147
Insulin receptor signalling cascade R-HSA-74751
G alpha (q) signalling events R-HSA-416476
Signaling by NODAL R-HSA-1181150
PIP3 activates AKT signaling R-HSA-1257604
Regulation of the apoptosome activity R-HSA-9627069
Signaling by FGFR4 R-HSA-5654743
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK1/MAPK3 signaling R-HSA-5684996
NCAM signaling for neurite out-growth R-HSA-375165
Oncogene Induced Senescence R-HSA-2559585
Apoptosis R-HSA-109581
RNA Polymerase I Transcription R-HSA-73864
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Intrinsic Pathway for Apoptosis R-HSA-109606
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Parasite infection R-HSA-9664407
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Infection with Mycobacterium tuberculosis R-HSA-9635486
RHO GTPase Effectors R-HSA-195258
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Innate Immune System R-HSA-168249
Negative regulation of MAPK pathway R-HSA-5675221
Spry regulation of FGF signaling R-HSA-1295596
Leishmania phagocytosis R-HSA-9664417
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by FGFR1 R-HSA-5654736
MAP kinase activation R-HSA-450294
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by ALK fusions and activated point mutants R-HSA-9725370
ISG15 antiviral mechanism R-HSA-1169408
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Cytokine Signaling in Immune system R-HSA-1280215
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Negative regulation of the PI3K/AKT network R-HSA-199418
Toll-like Receptor Cascades R-HSA-168898
RAF/MAP kinase cascade R-HSA-5673001
Leishmania infection R-HSA-9658195
Generic Transcription Pathway R-HSA-212436
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Apoptotic factor-mediated response R-HSA-111471
MAPK3 (ERK1) activation R-HSA-110056
Platelet activation, signaling and aggregation R-HSA-76002
RUNX2 regulates bone development R-HSA-8941326
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Prolonged ERK activation events R-HSA-169893
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Growth hormone receptor signaling R-HSA-982772
MyD88 cascade initiated on plasma membrane R-HSA-975871
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
ISG15 antiviral mechanism R-HSA-1169408
Negative regulation of FGFR4 signaling R-HSA-5654733
Platelet activation, signaling and aggregation R-HSA-76002
RNA Polymerase I Promoter Opening R-HSA-73728
Parasite infection R-HSA-9664407
Axon guidance R-HSA-422475
RNA Polymerase I Promoter Clearance R-HSA-73854
Negative feedback regulation of MAPK pathway R-HSA-5674499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Prolonged ERK activation events R-HSA-169893
Toll-like Receptor Cascades R-HSA-168898
Signal transduction by L1 R-HSA-445144
Cellular Senescence R-HSA-2559583
NCAM signaling for neurite out-growth R-HSA-375165
L1CAM interactions R-HSA-373760
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Gene expression (Transcription) R-HSA-74160
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Signaling by NTRK1 (TRKA) R-HSA-187037
Cell Cycle R-HSA-1640170
Formation of apoptosome R-HSA-111458
Interleukin-17 signaling R-HSA-448424
Transcriptional regulation by RUNX2 R-HSA-8878166
NPAS4 regulates expression of target genes R-HSA-9768919
Hemostasis R-HSA-109582
Cellular responses to stimuli R-HSA-8953897
RAF-independent MAPK1/3 activation R-HSA-112409
Signalling to ERKs R-HSA-187687
Signaling by FGFR2 R-HSA-5654738
Negative regulation of MAPK pathway R-HSA-5675221
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Transmission across Chemical Synapses R-HSA-112315
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signaling by Insulin receptor R-HSA-74752
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Cytokine Signaling in Immune system R-HSA-1280215
ERK/MAPK targets R-HSA-198753
Signaling by Activin R-HSA-1502540
Interferon Signaling R-HSA-913531
Signaling by GPCR R-HSA-372790
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stress R-HSA-2262752
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Rho GTPases R-HSA-194315
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Transcriptional Regulation by NPAS4 R-HSA-9634815
RHO GTPase Effectors R-HSA-195258
Signal attenuation R-HSA-74749
Oncogenic MAPK signaling R-HSA-6802957
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling downstream of RAS mutants R-HSA-9649948
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAP kinase activation R-HSA-450294
Signaling by RAS mutants R-HSA-6802949
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Leishmania infection R-HSA-9658195
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by FGFR4 R-HSA-5654743
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by NODAL R-HSA-1181150
RUNX2 regulates bone development R-HSA-8941326
ERKs are inactivated R-HSA-202670
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by MAP2K mutants R-HSA-9652169
Signaling by FGFR1 R-HSA-5654736
Signaling by TGF-beta Receptor Complex R-HSA-170834
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Extra-nuclear estrogen signaling R-HSA-9009391
Nervous system development R-HSA-9675108
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Oncogene Induced Senescence R-HSA-2559585
Cell Cycle, Mitotic R-HSA-69278
Disease R-HSA-1643685
Signaling by FGFR3 R-HSA-5654741
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
PIP3 activates AKT signaling R-HSA-1257604
ESR-mediated signaling R-HSA-8939211
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RSK activation R-HSA-444257
Immune System R-HSA-168256
RAF/MAP kinase cascade R-HSA-5673001
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by NTRKs R-HSA-166520
Apoptotic factor-mediated response R-HSA-111471
Negative regulation of FGFR1 signaling R-HSA-5654726
Leishmania phagocytosis R-HSA-9664417
Programmed Cell Death R-HSA-5357801
Signaling by TGFB family members R-HSA-9006936
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Innate Immune System R-HSA-168249
Neuronal System R-HSA-112316
Oxidative Stress Induced Senescence R-HSA-2559580
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RNA Polymerase II Transcription R-HSA-73857
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Cytochrome c-mediated apoptotic response R-HSA-111461
M Phase R-HSA-68886
Post NMDA receptor activation events R-HSA-438064
G alpha (q) signalling events R-HSA-416476
Spry regulation of FGF signaling R-HSA-1295596
FCERI mediated MAPK activation R-HSA-2871796
PTEN Regulation R-HSA-6807070
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Cellular response to heat stress R-HSA-3371556
Suppression of apoptosis R-HSA-9635465
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Response of Mtb to phagocytosis R-HSA-9637690
MAPK3 (ERK1) activation R-HSA-110056
Signaling by RAF1 mutants R-HSA-9656223
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MAP2K and MAPK activation R-HSA-5674135
Signaling by ALK in cancer R-HSA-9700206
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR R-HSA-190236
Intracellular signaling by second messengers R-HSA-9006925
Regulation of the apoptosome activity R-HSA-9627069
Infectious disease R-HSA-5663205
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
RNA Polymerase I Transcription R-HSA-73864
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Negative regulation of FGFR2 signaling R-HSA-5654727
FCGR3A-mediated phagocytosis R-HSA-9664422
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Developmental Biology R-HSA-1266738
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Apoptosis R-HSA-109581
Signaling by ALK fusions and activated point mutants R-HSA-9725370
MAPK family signaling cascades R-HSA-5683057
Frs2-mediated activation R-HSA-170968
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
Mitotic Prophase R-HSA-68875
Negative regulation of the PI3K/AKT network R-HSA-199418
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Regulation of the apoptosome activity R-HSA-9627069
Signaling by RAF1 mutants R-HSA-9656223
Parasite infection R-HSA-9664407
Signaling by NTRKs R-HSA-166520
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Generic Transcription Pathway R-HSA-212436
Signaling by NODAL R-HSA-1181150
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
FCGR3A-mediated phagocytosis R-HSA-9664422
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Apoptosis R-HSA-109581
Oncogenic MAPK signaling R-HSA-6802957
Signaling by MAP2K mutants R-HSA-9652169
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Signaling by FGFR4 R-HSA-5654743
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Apoptotic factor-mediated response R-HSA-111471
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by FGFR2 R-HSA-5654738
Negative feedback regulation of MAPK pathway R-HSA-5674499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NCAM signaling for neurite out-growth R-HSA-375165
RNA Polymerase I Transcription R-HSA-73864
Cellular response to heat stress R-HSA-3371556
Neuronal System R-HSA-112316
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MyD88 cascade initiated on plasma membrane R-HSA-975871
RNA Polymerase I Promoter Clearance R-HSA-73854
Cell Cycle, Mitotic R-HSA-69278
RSK activation R-HSA-444257
Programmed Cell Death R-HSA-5357801
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signal transduction by L1 R-HSA-445144
Infectious disease R-HSA-5663205
Formation of apoptosome R-HSA-111458
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RUNX2 regulates osteoblast differentiation R-HSA-8940973
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by Insulin receptor R-HSA-74752
Regulation of PTEN gene transcription R-HSA-8943724
Interferon Signaling R-HSA-913531
Oxidative Stress Induced Senescence R-HSA-2559580
NPAS4 regulates expression of target genes R-HSA-9768919
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling downstream of RAS mutants R-HSA-9649948
Frs2-mediated activation R-HSA-170968
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 dependent cascade initiated on endosome R-HSA-975155
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
MAP kinase activation R-HSA-450294
RNA Polymerase I Promoter Opening R-HSA-73728
Signaling by BRAF and RAF1 fusions R-HSA-6802952
ISG15 antiviral mechanism R-HSA-1169408
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
ERKs are inactivated R-HSA-202670
Leishmania phagocytosis R-HSA-9664417
Leishmania infection R-HSA-9658195
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FGFR R-HSA-190236
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
L1CAM interactions R-HSA-373760
Insulin receptor signalling cascade R-HSA-74751
MAPK family signaling cascades R-HSA-5683057
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular responses to stimuli R-HSA-8953897
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signal attenuation R-HSA-74749
Intracellular signaling by second messengers R-HSA-9006925
Growth hormone receptor signaling R-HSA-982772
Signaling by NTRK1 (TRKA) R-HSA-187037
Prolonged ERK activation events R-HSA-169893
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAP2K and MAPK activation R-HSA-5674135
RAF/MAP kinase cascade R-HSA-5673001
Hemostasis R-HSA-109582
Toll-like Receptor Cascades R-HSA-168898
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by Rho GTPases R-HSA-194315
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Axon guidance R-HSA-422475
MAPK3 (ERK1) activation R-HSA-110056
Signaling by FGFR3 R-HSA-5654741
ESR-mediated signaling R-HSA-8939211
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
M Phase R-HSA-68886
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RHO GTPase Effectors R-HSA-195258
Mitotic Prophase R-HSA-68875
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by RAS mutants R-HSA-6802949
Platelet activation, signaling and aggregation R-HSA-76002
Innate Immune System R-HSA-168249
Post NMDA receptor activation events R-HSA-438064
Negative regulation of FGFR3 signaling R-HSA-5654732
Oncogene Induced Senescence R-HSA-2559585
Negative regulation of FGFR2 signaling R-HSA-5654727
Signalling to ERKs R-HSA-187687
Cellular Senescence R-HSA-2559583
Signaling by ALK in cancer R-HSA-9700206
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Activin R-HSA-1502540
Transcriptional regulation by RUNX2 R-HSA-8878166
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by FGFR1 R-HSA-5654736
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Interleukins R-HSA-449147
Negative regulation of MAPK pathway R-HSA-5675221
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Transmission across Chemical Synapses R-HSA-112315
FCERI mediated MAPK activation R-HSA-2871796
Suppression of apoptosis R-HSA-9635465
RUNX2 regulates bone development R-HSA-8941326
Signaling by TGF-beta Receptor Complex R-HSA-170834
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Response of Mtb to phagocytosis R-HSA-9637690
Transcriptional Regulation by NPAS4 R-HSA-9634815
RAF-independent MAPK1/3 activation R-HSA-112409
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
ERK/MAPK targets R-HSA-198753
Signaling by TGFB family members R-HSA-9006936
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Spry regulation of FGF signaling R-HSA-1295596
PIP3 activates AKT signaling R-HSA-1257604
Activation of the AP-1 family of transcription factors R-HSA-450341
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
RNA Polymerase II Transcription R-HSA-73857
Extra-nuclear estrogen signaling R-HSA-9009391
Interleukin-17 signaling R-HSA-448424
FCERI mediated MAPK activation R-HSA-2871796
Developmental Biology R-HSA-1266738
Signaling by NTRK1 (TRKA) R-HSA-187037
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR4 signaling R-HSA-5654733
Prolonged ERK activation events R-HSA-169893
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cellular responses to stress R-HSA-2262752
Signaling by GPCR R-HSA-372790
Negative feedback regulation of MAPK pathway R-HSA-5674499
RNA Polymerase I Transcription R-HSA-73864
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by TGFB family members R-HSA-9006936
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll-like Receptor Cascades R-HSA-168898
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
M Phase R-HSA-68886
Signaling by FGFR4 R-HSA-5654743
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Apoptosis R-HSA-109581
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of NMDA receptors and postsynaptic events R-HSA-442755
ESR-mediated signaling R-HSA-8939211
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Activin R-HSA-1502540
Cytokine Signaling in Immune system R-HSA-1280215
Oncogene Induced Senescence R-HSA-2559585
MAP kinase activation R-HSA-450294
Immune System R-HSA-168256
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MAPK3 (ERK1) activation R-HSA-110056
Neuronal System R-HSA-112316
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MAPK family signaling cascades R-HSA-5683057
Signaling by TGF-beta Receptor Complex R-HSA-170834
Negative regulation of MAPK pathway R-HSA-5675221
RUNX2 regulates bone development R-HSA-8941326
Interferon Signaling R-HSA-913531
RAF-independent MAPK1/3 activation R-HSA-112409
Generic Transcription Pathway R-HSA-212436
Signaling by FGFR R-HSA-190236
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Infection with Mycobacterium tuberculosis R-HSA-9635486
Negative regulation of FGFR1 signaling R-HSA-5654726
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Cellular responses to stimuli R-HSA-8953897
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular Senescence R-HSA-2559583
MyD88 cascade initiated on plasma membrane R-HSA-975871
Intracellular signaling by second messengers R-HSA-9006925
Signalling to ERKs R-HSA-187687
Signal attenuation R-HSA-74749
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Leishmania infection R-HSA-9658195
Regulation of the apoptosome activity R-HSA-9627069
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
MyD88 dependent cascade initiated on endosome R-HSA-975155
Hemostasis R-HSA-109582
Signaling by Nuclear Receptors R-HSA-9006931
Frs2-mediated activation R-HSA-170968
Post NMDA receptor activation events R-HSA-438064
Transmission across Chemical Synapses R-HSA-112315
Signaling by NODAL R-HSA-1181150
Suppression of apoptosis R-HSA-9635465
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by FGFR3 R-HSA-5654741
Infectious disease R-HSA-5663205
Signaling by ALK in cancer R-HSA-9700206
GPCR downstream signalling R-HSA-388396
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Transcriptional regulation by RUNX2 R-HSA-8878166
RSK activation R-HSA-444257
FCGR3A-mediated phagocytosis R-HSA-9664422
Oncogenic MAPK signaling R-HSA-6802957
Formation of apoptosome R-HSA-111458
Negative regulation of FGFR2 signaling R-HSA-5654727
Regulation of PTEN gene transcription R-HSA-8943724
Programmed Cell Death R-HSA-5357801
Signal transduction by L1 R-HSA-445144
Interleukin-17 signaling R-HSA-448424
Signaling by Rho GTPases R-HSA-194315
Cell Cycle, Mitotic R-HSA-69278
Insulin receptor signalling cascade R-HSA-74751
Negative regulation of the PI3K/AKT network R-HSA-199418
MAP2K and MAPK activation R-HSA-5674135
NPAS4 regulates expression of target genes R-HSA-9768919
Transcriptional Regulation by NPAS4 R-HSA-9634815
Activation of the AP-1 family of transcription factors R-HSA-450341
Disease R-HSA-1643685
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Negative regulation of FGFR3 signaling R-HSA-5654732
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by RAF1 mutants R-HSA-9656223
Intrinsic Pathway for Apoptosis R-HSA-109606
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Extra-nuclear estrogen signaling R-HSA-9009391
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Response of Mtb to phagocytosis R-HSA-9637690
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MAPK1/MAPK3 signaling R-HSA-5684996
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Mitotic Prophase R-HSA-68875
RHO GTPase Effectors R-HSA-195258
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by MAP2K mutants R-HSA-9652169
MyD88-independent TLR4 cascade R-HSA-166166
RAF/MAP kinase cascade R-HSA-5673001
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Oxidative Stress Induced Senescence R-HSA-2559580
Apoptotic factor-mediated response R-HSA-111471
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Axon guidance R-HSA-422475
L1CAM interactions R-HSA-373760
Leishmania phagocytosis R-HSA-9664417
Signal Transduction R-HSA-162582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Spry regulation of FGF signaling R-HSA-1295596
ERKs are inactivated R-HSA-202670
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by NTRKs R-HSA-166520
Growth hormone receptor signaling R-HSA-982772
Signaling by Insulin receptor R-HSA-74752
Parasite infection R-HSA-9664407
Signaling by RAS mutants R-HSA-6802949
Innate Immune System R-HSA-168249
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by FGFR2 R-HSA-5654738
Cytochrome c-mediated apoptotic response R-HSA-111461
RNA Polymerase I Promoter Opening R-HSA-73728
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by FGFR1 R-HSA-5654736
Nervous system development R-HSA-9675108
ISG15 antiviral mechanism R-HSA-1169408
Cell Cycle R-HSA-1640170
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Transcriptional Regulation by NPAS4 R-HSA-9634815
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
ESR-mediated signaling R-HSA-8939211
MAP2K and MAPK activation R-HSA-5674135
Developmental Biology R-HSA-1266738
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
RNA Polymerase I Promoter Opening R-HSA-73728
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Interleukin-17 signaling R-HSA-448424
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Neuronal System R-HSA-112316
RSK activation R-HSA-444257
MyD88-independent TLR4 cascade R-HSA-166166
Post NMDA receptor activation events R-HSA-438064
Signaling by Insulin receptor R-HSA-74752
RUNX2 regulates bone development R-HSA-8941326
Oxidative Stress Induced Senescence R-HSA-2559580
Activation of the AP-1 family of transcription factors R-HSA-450341
Activation of NMDA receptors and postsynaptic events R-HSA-442755
M Phase R-HSA-68886
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Activin R-HSA-1502540
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signal attenuation R-HSA-74749
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Interferon Signaling R-HSA-913531
Growth hormone receptor signaling R-HSA-982772
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by FGFR4 R-HSA-5654743
Signaling by RAF1 mutants R-HSA-9656223
Oncogenic MAPK signaling R-HSA-6802957
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Spry regulation of FGF signaling R-HSA-1295596
MAP kinase activation R-HSA-450294
Apoptotic factor-mediated response R-HSA-111471
RNA Polymerase II Transcription R-HSA-73857
Infection with Mycobacterium tuberculosis R-HSA-9635486
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
FCGR3A-mediated phagocytosis R-HSA-9664422
GPCR downstream signalling R-HSA-388396
Signaling by FGFR3 R-HSA-5654741
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Innate Immune System R-HSA-168249
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR1 R-HSA-5654736
ERK/MAPK targets R-HSA-198753
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Extra-nuclear estrogen signaling R-HSA-9009391
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RUNX2 regulates osteoblast differentiation R-HSA-8940973
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by NTRKs R-HSA-166520
Leishmania infection R-HSA-9658195
Programmed Cell Death R-HSA-5357801
Parasite infection R-HSA-9664407
MyD88 dependent cascade initiated on endosome R-HSA-975155
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by TGFB family members R-HSA-9006936
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NCAM signaling for neurite out-growth R-HSA-375165
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
L1CAM interactions R-HSA-373760
Signal Transduction R-HSA-162582
Frs2-mediated activation R-HSA-170968
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll-like Receptor Cascades R-HSA-168898
Negative regulation of MAPK pathway R-HSA-5675221
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
FCERI mediated MAPK activation R-HSA-2871796
Signaling by MAP2K mutants R-HSA-9652169
Signaling by ALK in cancer R-HSA-9700206
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Cellular Senescence R-HSA-2559583
Infectious disease R-HSA-5663205
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Generic Transcription Pathway R-HSA-212436
Intrinsic Pathway for Apoptosis R-HSA-109606
Mitotic Prophase R-HSA-68875
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by GPCR R-HSA-372790
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling downstream of RAS mutants R-HSA-9649948
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RNA Polymerase I Transcription R-HSA-73864
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by RAS mutants R-HSA-6802949
ERKs are inactivated R-HSA-202670
Cell Cycle, Mitotic R-HSA-69278
Regulation of PTEN gene transcription R-HSA-8943724
Negative regulation of FGFR3 signaling R-HSA-5654732
MAPK family signaling cascades R-HSA-5683057
Negative regulation of FGFR1 signaling R-HSA-5654726
RAF/MAP kinase cascade R-HSA-5673001
Formation of apoptosome R-HSA-111458
Signaling by Nuclear Receptors R-HSA-9006931
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by NTRK1 (TRKA) R-HSA-187037
Immune System R-HSA-168256
Signaling by TGF-beta Receptor Complex R-HSA-170834
PIP3 activates AKT signaling R-HSA-1257604
MAPK3 (ERK1) activation R-HSA-110056
RAF-independent MAPK1/3 activation R-HSA-112409
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
MAPK1/MAPK3 signaling R-HSA-5684996
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cytochrome c-mediated apoptotic response R-HSA-111461
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of the apoptosome activity R-HSA-9627069
Signal transduction by L1 R-HSA-445144
Hemostasis R-HSA-109582
Oncogene Induced Senescence R-HSA-2559585
RHO GTPase Effectors R-HSA-195258
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Suppression of apoptosis R-HSA-9635465
Signaling by FGFR R-HSA-190236
Apoptosis R-HSA-109581
G alpha (q) signalling events R-HSA-416476
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Nervous system development R-HSA-9675108
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
PTEN Regulation R-HSA-6807070
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by FGFR2 R-HSA-5654738
Prolonged ERK activation events R-HSA-169893
Negative regulation of FGFR4 signaling R-HSA-5654733
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular response to heat stress R-HSA-3371556
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by Rho GTPases R-HSA-194315
Signaling by NODAL R-HSA-1181150
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Transmission across Chemical Synapses R-HSA-112315
Leishmania phagocytosis R-HSA-9664417
Response of Mtb to phagocytosis R-HSA-9637690
Cellular responses to stimuli R-HSA-8953897
Signalling to ERKs R-HSA-187687
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
FCGR3A-mediated phagocytosis R-HSA-9664422
Prolonged ERK activation events R-HSA-169893
Programmed Cell Death R-HSA-5357801
Signaling by NTRKs R-HSA-166520
Negative regulation of FGFR2 signaling R-HSA-5654727
Neuronal System R-HSA-112316
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Activin R-HSA-1502540
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by FGFR4 R-HSA-5654743
Apoptotic factor-mediated response R-HSA-111471
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Oncogene Induced Senescence R-HSA-2559585
Response of Mtb to phagocytosis R-HSA-9637690
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
ERKs are inactivated R-HSA-202670
Apoptosis R-HSA-109581
RHO GTPase Effectors R-HSA-195258
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by ALK fusions and activated point mutants R-HSA-9725370
RNA Polymerase II Transcription R-HSA-73857
MyD88 dependent cascade initiated on endosome R-HSA-975155
Formation of apoptosome R-HSA-111458
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Extra-nuclear estrogen signaling R-HSA-9009391
RSK activation R-HSA-444257
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Toll-like Receptor Cascades R-HSA-168898
Cell Cycle R-HSA-1640170
Innate Immune System R-HSA-168249
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Axon guidance R-HSA-422475
Signaling by ALK in cancer R-HSA-9700206
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
L1CAM interactions R-HSA-373760
Infection with Mycobacterium tuberculosis R-HSA-9635486
RNA Polymerase I Promoter Opening R-HSA-73728
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Frs2-mediated activation R-HSA-170968
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Hemostasis R-HSA-109582
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR3 R-HSA-5654741
ESR-mediated signaling R-HSA-8939211
Signaling by FGFR R-HSA-190236
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
RNA Polymerase I Transcription R-HSA-73864
Signaling by RAF1 mutants R-HSA-9656223
MAPK family signaling cascades R-HSA-5683057
Cellular Senescence R-HSA-2559583
Platelet activation, signaling and aggregation R-HSA-76002
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by NODAL R-HSA-1181150
Signalling to ERKs R-HSA-187687
Nervous system development R-HSA-9675108
Negative regulation of MAPK pathway R-HSA-5675221
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cell Cycle, Mitotic R-HSA-69278
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G alpha (q) signalling events R-HSA-416476
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Signaling by FGFR1 R-HSA-5654736
Insulin receptor signalling cascade R-HSA-74751
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Spry regulation of FGF signaling R-HSA-1295596
Cellular responses to stress R-HSA-2262752
GPCR downstream signalling R-HSA-388396
Intracellular signaling by second messengers R-HSA-9006925
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
MAP2K and MAPK activation R-HSA-5674135
Signaling by FGFR2 R-HSA-5654738
RUNX2 regulates bone development R-HSA-8941326
Activation of the AP-1 family of transcription factors R-HSA-450341
Suppression of apoptosis R-HSA-9635465
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-17 signaling R-HSA-448424
Disease R-HSA-1643685
Leishmania infection R-HSA-9658195
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signal attenuation R-HSA-74749
Signaling by Nuclear Receptors R-HSA-9006931
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by RAS mutants R-HSA-6802949
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK3 (ERK1) activation R-HSA-110056
Signaling by Rho GTPases R-HSA-194315
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Regulation of the apoptosome activity R-HSA-9627069
Growth hormone receptor signaling R-HSA-982772
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by MAP2K mutants R-HSA-9652169
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
ERK/MAPK targets R-HSA-198753
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Leishmania phagocytosis R-HSA-9664417
Cellular responses to stimuli R-HSA-8953897
Signaling by Interleukins R-HSA-449147
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signal transduction by L1 R-HSA-445144
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by GPCR R-HSA-372790
Negative feedback regulation of MAPK pathway R-HSA-5674499
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Negative regulation of FGFR1 signaling R-HSA-5654726
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RNA Polymerase I Promoter Clearance R-HSA-73854
Parasite infection R-HSA-9664407
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by TGFB family members R-HSA-9006936
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated MAPK activation R-HSA-2871796
MAP kinase activation R-HSA-450294
Transcriptional Regulation by NPAS4 R-HSA-9634815
Negative regulation of the PI3K/AKT network R-HSA-199418
Interferon Signaling R-HSA-913531
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intrinsic Pathway for Apoptosis R-HSA-109606
Post NMDA receptor activation events R-HSA-438064
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Infectious disease R-HSA-5663205
Transmission across Chemical Synapses R-HSA-112315
Regulation of PTEN gene transcription R-HSA-8943724
Oncogenic MAPK signaling R-HSA-6802957
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Extra-nuclear estrogen signaling R-HSA-9009391
Interferon Signaling R-HSA-913531
Transmission across Chemical Synapses R-HSA-112315
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR1 R-HSA-5654736
Apoptotic factor-mediated response R-HSA-111471
Signal transduction by L1 R-HSA-445144
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Rho GTPases R-HSA-194315
Leishmania phagocytosis R-HSA-9664417
MAPK family signaling cascades R-HSA-5683057
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
RNA Polymerase I Promoter Opening R-HSA-73728
Signaling by NODAL R-HSA-1181150
Immune System R-HSA-168256
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Post NMDA receptor activation events R-HSA-438064
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Hemostasis R-HSA-109582
Suppression of apoptosis R-HSA-9635465
Activation of the AP-1 family of transcription factors R-HSA-450341
PTEN Regulation R-HSA-6807070
Programmed Cell Death R-HSA-5357801
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by NTRKs R-HSA-166520
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Oncogenic MAPK signaling R-HSA-6802957
RNA Polymerase I Transcription R-HSA-73864
Interleukin-17 signaling R-HSA-448424
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR4 R-HSA-5654743
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Negative regulation of the PI3K/AKT network R-HSA-199418
Platelet activation, signaling and aggregation R-HSA-76002
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Insulin receptor R-HSA-74752
FCERI mediated MAPK activation R-HSA-2871796
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Frs2-mediated activation R-HSA-170968
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling downstream of RAS mutants R-HSA-9649948
Developmental Biology R-HSA-1266738
Negative regulation of FGFR1 signaling R-HSA-5654726
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Nuclear Receptors R-HSA-9006931
Mitotic Prophase R-HSA-68875
Neuronal System R-HSA-112316
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Growth hormone receptor signaling R-HSA-982772
MAP kinase activation R-HSA-450294
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll-like Receptor Cascades R-HSA-168898
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
MAPK3 (ERK1) activation R-HSA-110056
Signaling by FGFR3 R-HSA-5654741
Signaling by FGFR2 R-HSA-5654738
Parasite infection R-HSA-9664407
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by ALK in cancer R-HSA-9700206
Signaling by TGFB family members R-HSA-9006936
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by RAS mutants R-HSA-6802949
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
RUNX2 regulates bone development R-HSA-8941326
L1CAM interactions R-HSA-373760
Gene expression (Transcription) R-HSA-74160
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Prolonged ERK activation events R-HSA-169893
ERK/MAPK targets R-HSA-198753
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Oncogene Induced Senescence R-HSA-2559585
Negative feedback regulation of MAPK pathway R-HSA-5674499
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular response to heat stress R-HSA-3371556
Transcriptional regulation by RUNX2 R-HSA-8878166
Response of Mtb to phagocytosis R-HSA-9637690
Intracellular signaling by second messengers R-HSA-9006925
RAF-independent MAPK1/3 activation R-HSA-112409
RSK activation R-HSA-444257
Signaling by MAP2K mutants R-HSA-9652169
Nervous system development R-HSA-9675108
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Negative regulation of FGFR2 signaling R-HSA-5654727
MyD88 cascade initiated on plasma membrane R-HSA-975871
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of FGFR4 signaling R-HSA-5654733
Oxidative Stress Induced Senescence R-HSA-2559580
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR R-HSA-190236
Signaling by GPCR R-HSA-372790
Signaling by TGF-beta Receptor Complex R-HSA-170834
GPCR downstream signalling R-HSA-388396
Negative regulation of MAPK pathway R-HSA-5675221
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
M Phase R-HSA-68886
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Apoptosis R-HSA-109581
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Leishmania infection R-HSA-9658195
Intrinsic Pathway for Apoptosis R-HSA-109606
MyD88-independent TLR4 cascade R-HSA-166166
MAP2K and MAPK activation R-HSA-5674135
ERKs are inactivated R-HSA-202670
ESR-mediated signaling R-HSA-8939211
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
NPAS4 regulates expression of target genes R-HSA-9768919
Cellular responses to stimuli R-HSA-8953897
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Cellular Senescence R-HSA-2559583
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signalling to ERKs R-HSA-187687
Spry regulation of FGF signaling R-HSA-1295596
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Innate Immune System R-HSA-168249
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Signaling by NTRK1 (TRKA) R-HSA-187037
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
PIP3 activates AKT signaling R-HSA-1257604
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Formation of apoptosome R-HSA-111458
Regulation of the apoptosome activity R-HSA-9627069
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
RHO GTPase Effectors R-HSA-195258
MAPK1/MAPK3 signaling R-HSA-5684996
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signal attenuation R-HSA-74749
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of PTEN gene transcription R-HSA-8943724
Infection with Mycobacterium tuberculosis R-HSA-9635486
G alpha (q) signalling events R-HSA-416476
Signaling by Activin R-HSA-1502540
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR4 R-HSA-5654743
RNA Polymerase I Promoter Clearance R-HSA-73854
Activation of the AP-1 family of transcription factors R-HSA-450341
Infection with Mycobacterium tuberculosis R-HSA-9635486
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
MyD88-independent TLR4 cascade R-HSA-166166
PIP3 activates AKT signaling R-HSA-1257604
Regulation of HSF1-mediated heat shock response R-HSA-3371453
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by MAP2K mutants R-HSA-9652169
RSK activation R-HSA-444257
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MAPK family signaling cascades R-HSA-5683057
Signaling by NTRKs R-HSA-166520
Signaling by FGFR3 R-HSA-5654741
Developmental Biology R-HSA-1266738
Oncogenic MAPK signaling R-HSA-6802957
Suppression of apoptosis R-HSA-9635465
ERK/MAPK targets R-HSA-198753
Spry regulation of FGF signaling R-HSA-1295596
Disease R-HSA-1643685
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cell Cycle, Mitotic R-HSA-69278
Signaling by NTRK1 (TRKA) R-HSA-187037
Programmed Cell Death R-HSA-5357801
Axon guidance R-HSA-422475
Signaling downstream of RAS mutants R-HSA-9649948
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Oncogene Induced Senescence R-HSA-2559585
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Extra-nuclear estrogen signaling R-HSA-9009391
Signal transduction by L1 R-HSA-445144
Toll-like Receptor Cascades R-HSA-168898
Cellular response to heat stress R-HSA-3371556
Regulation of PTEN gene transcription R-HSA-8943724
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Prolonged ERK activation events R-HSA-169893
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Transmission across Chemical Synapses R-HSA-112315
Parasite infection R-HSA-9664407
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Generic Transcription Pathway R-HSA-212436
Negative regulation of the PI3K/AKT network R-HSA-199418
Cellular responses to stress R-HSA-2262752
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Frs2-mediated activation R-HSA-170968
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Intrinsic Pathway for Apoptosis R-HSA-109606
Formation of apoptosome R-HSA-111458
ISG15 antiviral mechanism R-HSA-1169408
Negative regulation of FGFR1 signaling R-HSA-5654726
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Cytokine Signaling in Immune system R-HSA-1280215
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAP kinase activation R-HSA-450294
RNA Polymerase I Promoter Opening R-HSA-73728
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
NCAM signaling for neurite out-growth R-HSA-375165
Leishmania phagocytosis R-HSA-9664417
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Interferon Signaling R-HSA-913531
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR2 signaling R-HSA-5654727
RUNX2 regulates bone development R-HSA-8941326
Interleukin-17 signaling R-HSA-448424
Immune System R-HSA-168256
Signaling by Insulin receptor R-HSA-74752
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Insulin receptor signalling cascade R-HSA-74751
Signaling by NODAL R-HSA-1181150
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Negative regulation of MAPK pathway R-HSA-5675221
Signal Transduction R-HSA-162582
Regulation of the apoptosome activity R-HSA-9627069
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Post NMDA receptor activation events R-HSA-438064
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Apoptotic factor-mediated response R-HSA-111471
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signal attenuation R-HSA-74749
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Hemostasis R-HSA-109582
MAP2K and MAPK activation R-HSA-5674135
ERKs are inactivated R-HSA-202670
Growth hormone receptor signaling R-HSA-982772
L1CAM interactions R-HSA-373760
Signaling by Rho GTPases R-HSA-194315
ESR-mediated signaling R-HSA-8939211
FCERI mediated MAPK activation R-HSA-2871796
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Response of Mtb to phagocytosis R-HSA-9637690
Neuronal System R-HSA-112316
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Cell Cycle R-HSA-1640170
RHO GTPase Effectors R-HSA-195258
Signaling by Nuclear Receptors R-HSA-9006931
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Oxidative Stress Induced Senescence R-HSA-2559580
Apoptosis R-HSA-109581
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signalling to ERKs R-HSA-187687
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
GPCR downstream signalling R-HSA-388396
RNA Polymerase I Transcription R-HSA-73864
Signaling by FGFR2 R-HSA-5654738
PTEN Regulation R-HSA-6807070
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by RAS mutants R-HSA-6802949
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by FGFR R-HSA-190236
Cytochrome c-mediated apoptotic response R-HSA-111461
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by ALK in cancer R-HSA-9700206
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by RAF1 mutants R-HSA-9656223
Cellular Senescence R-HSA-2559583
Transcriptional Regulation by NPAS4 R-HSA-9634815
Negative feedback regulation of MAPK pathway R-HSA-5674499
Cellular responses to stimuli R-HSA-8953897
Signaling by FGFR1 R-HSA-5654736
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by TGFB family members R-HSA-9006936
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Gene expression (Transcription) R-HSA-74160
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Leishmania infection R-HSA-9658195
Signaling by GPCR R-HSA-372790
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Activin R-HSA-1502540
MyD88 cascade initiated on plasma membrane R-HSA-975871
Negative regulation of FGFR3 signaling R-HSA-5654732
MAPK3 (ERK1) activation R-HSA-110056

Expression Atlas ENSG00000102882
NCBI gene (formerly Entrezgene) 5595
GeneCards 6877
HGNC Symbol HGNC:6877
MIM gene 601795
UniProtKB Gene Name P27361
WikiGene 5595
Gene: PRKCG
Ensembl ID : ENSG00000126583
Description: protein kinase C gamma
Gene Synonyms: MGC57564,PKCC,PKCG,SCA14
5 APIs:
200 Possible Orthologues:

G alpha (i) signalling events R-HSA-418594
DAG and IP3 signaling R-HSA-1489509
Transmission across Chemical Synapses R-HSA-112315
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
PLC beta mediated events R-HSA-112043
G alpha (z) signalling events R-HSA-418597
Beta-catenin independent WNT signaling R-HSA-3858494
CaM pathway R-HSA-111997
Signaling by WNT R-HSA-195721
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Trafficking of AMPA receptors R-HSA-399719
Intracellular signaling by second messengers R-HSA-9006925
Neuronal System R-HSA-112316
Platelet activation, signaling and aggregation R-HSA-76002
Disinhibition of SNARE formation R-HSA-114516
PCP/CE pathway R-HSA-4086400
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Calmodulin induced events R-HSA-111933
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Opioid Signalling R-HSA-111885
Ca-dependent events R-HSA-111996
Signal Transduction R-HSA-162582
WNT5A-dependent internalization of FZD4 R-HSA-5099900
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
PLC beta mediated events R-HSA-112043
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Opioid Signalling R-HSA-111885
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
GPCR downstream signalling R-HSA-388396
PCP/CE pathway R-HSA-4086400
G-protein mediated events R-HSA-112040
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
G alpha (i) signalling events R-HSA-418594
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (z) signalling events R-HSA-418597
Signaling by WNT R-HSA-195721
Calmodulin induced events R-HSA-111933
Intracellular signaling by second messengers R-HSA-9006925
Ca-dependent events R-HSA-111996
Signal Transduction R-HSA-162582
Trafficking of AMPA receptors R-HSA-399719
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by GPCR R-HSA-372790
CaM pathway R-HSA-111997
Disinhibition of SNARE formation R-HSA-114516
DAG and IP3 signaling R-HSA-1489509
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
G alpha (i) signalling events R-HSA-418594
PCP/CE pathway R-HSA-4086400
PLC beta mediated events R-HSA-112043
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Signaling by WNT R-HSA-195721
Ca-dependent events R-HSA-111996
DAG and IP3 signaling R-HSA-1489509
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
Intracellular signaling by second messengers R-HSA-9006925
WNT5A-dependent internalization of FZD4 R-HSA-5099900
G alpha (z) signalling events R-HSA-418597
Opioid Signalling R-HSA-111885
Beta-catenin independent WNT signaling R-HSA-3858494
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Calmodulin induced events R-HSA-111933
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Disinhibition of SNARE formation R-HSA-114516
CaM pathway R-HSA-111997
Trafficking of AMPA receptors R-HSA-399719
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Neuronal System R-HSA-112316
Beta-catenin independent WNT signaling R-HSA-3858494
DAG and IP3 signaling R-HSA-1489509
Calmodulin induced events R-HSA-111933
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Intracellular signaling by second messengers R-HSA-9006925
Trafficking of AMPA receptors R-HSA-399719
Signal Transduction R-HSA-162582
Ca-dependent events R-HSA-111996
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by WNT R-HSA-195721
G-protein mediated events R-HSA-112040
Signaling by GPCR R-HSA-372790
PCP/CE pathway R-HSA-4086400
PLC beta mediated events R-HSA-112043
G alpha (i) signalling events R-HSA-418594
G alpha (z) signalling events R-HSA-418597
GPCR downstream signalling R-HSA-388396
Opioid Signalling R-HSA-111885
Transmission across Chemical Synapses R-HSA-112315
CaM pathway R-HSA-111997
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Disinhibition of SNARE formation R-HSA-114516
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
DAG and IP3 signaling R-HSA-1489509
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signaling by WNT R-HSA-195721
PLC beta mediated events R-HSA-112043
Intracellular signaling by second messengers R-HSA-9006925
G-protein mediated events R-HSA-112040
PCP/CE pathway R-HSA-4086400
Neuronal System R-HSA-112316
Signal Transduction R-HSA-162582
Ca-dependent events R-HSA-111996
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Calmodulin induced events R-HSA-111933
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Disinhibition of SNARE formation R-HSA-114516
G alpha (z) signalling events R-HSA-418597
CaM pathway R-HSA-111997
Transmission across Chemical Synapses R-HSA-112315
Signaling by GPCR R-HSA-372790
Beta-catenin independent WNT signaling R-HSA-3858494
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Platelet activation, signaling and aggregation R-HSA-76002
Trafficking of AMPA receptors R-HSA-399719
Opioid Signalling R-HSA-111885
Beta-catenin independent WNT signaling R-HSA-3858494
G alpha (i) signalling events R-HSA-418594
Hemostasis R-HSA-109582
WNT5A-dependent internalization of FZD4 R-HSA-5099900
G-protein mediated events R-HSA-112040
Trafficking of AMPA receptors R-HSA-399719
PCP/CE pathway R-HSA-4086400
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Calmodulin induced events R-HSA-111933
GPCR downstream signalling R-HSA-388396
Disinhibition of SNARE formation R-HSA-114516
DAG and IP3 signaling R-HSA-1489509
Transmission across Chemical Synapses R-HSA-112315
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neuronal System R-HSA-112316
Ca-dependent events R-HSA-111996
G alpha (z) signalling events R-HSA-418597
Opioid Signalling R-HSA-111885
PLC beta mediated events R-HSA-112043
Intracellular signaling by second messengers R-HSA-9006925
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Signaling by WNT R-HSA-195721
Platelet activation, signaling and aggregation R-HSA-76002
CaM pathway R-HSA-111997
Signaling by GPCR R-HSA-372790
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signal Transduction R-HSA-162582
Beta-catenin independent WNT signaling R-HSA-3858494
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
GPCR downstream signalling R-HSA-388396
DAG and IP3 signaling R-HSA-1489509
Trafficking of AMPA receptors R-HSA-399719
Ca-dependent events R-HSA-111996
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signaling by GPCR R-HSA-372790
CaM pathway R-HSA-111997
Signaling by WNT R-HSA-195721
Calmodulin induced events R-HSA-111933
PLC beta mediated events R-HSA-112043
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neuronal System R-HSA-112316
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
Platelet activation, signaling and aggregation R-HSA-76002
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Transmission across Chemical Synapses R-HSA-112315
Opioid Signalling R-HSA-111885
Disinhibition of SNARE formation R-HSA-114516
G alpha (z) signalling events R-HSA-418597
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Hemostasis R-HSA-109582
CaM pathway R-HSA-111997
Trafficking of AMPA receptors R-HSA-399719
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Transmission across Chemical Synapses R-HSA-112315
Signaling by WNT R-HSA-195721
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Disinhibition of SNARE formation R-HSA-114516
G alpha (z) signalling events R-HSA-418597
DAG and IP3 signaling R-HSA-1489509
Platelet activation, signaling and aggregation R-HSA-76002
Neuronal System R-HSA-112316
Calmodulin induced events R-HSA-111933
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Opioid Signalling R-HSA-111885
Ca-dependent events R-HSA-111996
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
PLC beta mediated events R-HSA-112043
G-protein mediated events R-HSA-112040
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
CaM pathway R-HSA-111997
PLC beta mediated events R-HSA-112043
Beta-catenin independent WNT signaling R-HSA-3858494
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Opioid Signalling R-HSA-111885
Intracellular signaling by second messengers R-HSA-9006925
Trafficking of AMPA receptors R-HSA-399719
G alpha (i) signalling events R-HSA-418594
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
G-protein mediated events R-HSA-112040
Disinhibition of SNARE formation R-HSA-114516
PCP/CE pathway R-HSA-4086400
Neuronal System R-HSA-112316
Hemostasis R-HSA-109582
GPCR downstream signalling R-HSA-388396
Transmission across Chemical Synapses R-HSA-112315
Signaling by GPCR R-HSA-372790
Ca-dependent events R-HSA-111996
G alpha (z) signalling events R-HSA-418597
DAG and IP3 signaling R-HSA-1489509
Signaling by WNT R-HSA-195721
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Calmodulin induced events R-HSA-111933
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Disinhibition of SNARE formation R-HSA-114516
Opioid Signalling R-HSA-111885
Signal Transduction R-HSA-162582
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Beta-catenin independent WNT signaling R-HSA-3858494
Intracellular signaling by second messengers R-HSA-9006925
Ca-dependent events R-HSA-111996
Calmodulin induced events R-HSA-111933
Signaling by GPCR R-HSA-372790
G-protein mediated events R-HSA-112040
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
DAG and IP3 signaling R-HSA-1489509
Neuronal System R-HSA-112316
G alpha (z) signalling events R-HSA-418597
PCP/CE pathway R-HSA-4086400
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Platelet activation, signaling and aggregation R-HSA-76002
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by WNT R-HSA-195721
CaM pathway R-HSA-111997
G alpha (i) signalling events R-HSA-418594
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
PLC beta mediated events R-HSA-112043
Trafficking of AMPA receptors R-HSA-399719
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Transmission across Chemical Synapses R-HSA-112315

Expression Atlas ENSG00000126583
LRG display in Ensembl gene LRG_669
NCBI gene (formerly Entrezgene) 5582
GeneCards 9402
HGNC Symbol HGNC:9402
MIM gene 176980
MIM morbid 605361
UniProtKB Gene Name P05129
WikiGene 5582
Gene: ROCK2
Ensembl ID : ENSG00000134318
Description: Rho associated coiled-coil containing protein kinase 2
Gene Synonyms:
11 APIs:
298 Possible Orthologues:

Axon guidance R-HSA-422475
Signaling by Rho GTPases R-HSA-194315
G alpha (12/13) signalling events R-HSA-416482
RHOH GTPase cycle R-HSA-9013407
EPH-Ephrin signaling R-HSA-2682334
Infectious disease R-HSA-5663205
RHOB GTPase cycle R-HSA-9013026
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
RHOC GTPase cycle R-HSA-9013106
RHOA GTPase cycle R-HSA-8980692
Potential therapeutics for SARS R-HSA-9679191
RHOBTB GTPase Cycle R-HSA-9706574
RHO GTPase cycle R-HSA-9012999
RHOBTB1 GTPase cycle R-HSA-9013422
EPHB-mediated forward signaling R-HSA-3928662
Sema4D in semaphorin signaling R-HSA-400685
Disease R-HSA-1643685
Signaling by VEGF R-HSA-194138
EPHA-mediated growth cone collapse R-HSA-3928663
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Semaphorin interactions R-HSA-373755
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
RHO GTPase Effectors R-HSA-195258
SARS-CoV Infections R-HSA-9679506
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPases Activate ROCKs R-HSA-5627117
GPCR downstream signalling R-HSA-388396
RHOH GTPase cycle R-HSA-9013407
Disease R-HSA-1643685
RHOBTB GTPase Cycle R-HSA-9706574
RHO GTPase Effectors R-HSA-195258
Signaling by Rho GTPases R-HSA-194315
EPH-Ephrin signaling R-HSA-2682334
Signaling by VEGF R-HSA-194138
G alpha (12/13) signalling events R-HSA-416482
Sema4D in semaphorin signaling R-HSA-400685
Infectious disease R-HSA-5663205
Semaphorin interactions R-HSA-373755
VEGFA-VEGFR2 Pathway R-HSA-4420097
EPHB-mediated forward signaling R-HSA-3928662
EPHA-mediated growth cone collapse R-HSA-3928663
SARS-CoV Infections R-HSA-9679506
Nervous system development R-HSA-9675108
RHOA GTPase cycle R-HSA-8980692
RHOBTB1 GTPase cycle R-HSA-9013422
Signal Transduction R-HSA-162582
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Potential therapeutics for SARS R-HSA-9679191
GPCR downstream signalling R-HSA-388396
RHOC GTPase cycle R-HSA-9013106
Signaling by GPCR R-HSA-372790
RHO GTPase cycle R-HSA-9012999
RHOB GTPase cycle R-HSA-9013026
RHO GTPases Activate ROCKs R-HSA-5627117
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPHA-mediated growth cone collapse R-HSA-3928663
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Rho GTPases R-HSA-194315
RHOC GTPase cycle R-HSA-9013106
Nervous system development R-HSA-9675108
EPH-Ephrin signaling R-HSA-2682334
RHO GTPases Activate ROCKs R-HSA-5627117
RHOA GTPase cycle R-HSA-8980692
Developmental Biology R-HSA-1266738
Sema4D in semaphorin signaling R-HSA-400685
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPHB-mediated forward signaling R-HSA-3928662
RHOH GTPase cycle R-HSA-9013407
RHO GTPase cycle R-HSA-9012999
VEGFA-VEGFR2 Pathway R-HSA-4420097
Axon guidance R-HSA-422475
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Potential therapeutics for SARS R-HSA-9679191
G alpha (12/13) signalling events R-HSA-416482
SARS-CoV Infections R-HSA-9679506
Semaphorin interactions R-HSA-373755
RHOBTB GTPase Cycle R-HSA-9706574
Signaling by VEGF R-HSA-194138
RHOBTB1 GTPase cycle R-HSA-9013422
RHO GTPase Effectors R-HSA-195258
Infectious disease R-HSA-5663205
RHOB GTPase cycle R-HSA-9013026
RHOB GTPase cycle R-HSA-9013026
Signaling by VEGF R-HSA-194138
Sema4D in semaphorin signaling R-HSA-400685
RHO GTPase Effectors R-HSA-195258
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
RHOH GTPase cycle R-HSA-9013407
RHOBTB1 GTPase cycle R-HSA-9013422
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
G alpha (12/13) signalling events R-HSA-416482
RHOBTB GTPase Cycle R-HSA-9706574
Developmental Biology R-HSA-1266738
RHO GTPase cycle R-HSA-9012999
GPCR downstream signalling R-HSA-388396
RHOC GTPase cycle R-HSA-9013106
Signaling by GPCR R-HSA-372790
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPHB-mediated forward signaling R-HSA-3928662
Potential therapeutics for SARS R-HSA-9679191
Infectious disease R-HSA-5663205
EPH-Ephrin signaling R-HSA-2682334
Signaling by Rho GTPases R-HSA-194315
EPHA-mediated growth cone collapse R-HSA-3928663
Semaphorin interactions R-HSA-373755
Nervous system development R-HSA-9675108
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Disease R-HSA-1643685
Axon guidance R-HSA-422475
RHO GTPases Activate ROCKs R-HSA-5627117
RHOA GTPase cycle R-HSA-8980692
SARS-CoV Infections R-HSA-9679506
RHO GTPase Effectors R-HSA-195258
RHOC GTPase cycle R-HSA-9013106
Nervous system development R-HSA-9675108
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Axon guidance R-HSA-422475
RHO GTPase cycle R-HSA-9012999
Signaling by Rho GTPases R-HSA-194315
RHOH GTPase cycle R-HSA-9013407
EPHB-mediated forward signaling R-HSA-3928662
Disease R-HSA-1643685
EPH-Ephrin signaling R-HSA-2682334
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Infectious disease R-HSA-5663205
G alpha (12/13) signalling events R-HSA-416482
SARS-CoV Infections R-HSA-9679506
RHOB GTPase cycle R-HSA-9013026
Developmental Biology R-HSA-1266738
Potential therapeutics for SARS R-HSA-9679191
Signaling by GPCR R-HSA-372790
Sema4D in semaphorin signaling R-HSA-400685
Semaphorin interactions R-HSA-373755
RHOBTB1 GTPase cycle R-HSA-9013422
GPCR downstream signalling R-HSA-388396
RHOA GTPase cycle R-HSA-8980692
RHOBTB GTPase Cycle R-HSA-9706574
RHO GTPases Activate ROCKs R-HSA-5627117
VEGFA-VEGFR2 Pathway R-HSA-4420097
EPHA-mediated growth cone collapse R-HSA-3928663
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Semaphorin interactions R-HSA-373755
Developmental Biology R-HSA-1266738
Signaling by VEGF R-HSA-194138
RHO GTPase cycle R-HSA-9012999
EPHA-mediated growth cone collapse R-HSA-3928663
RHOB GTPase cycle R-HSA-9013026
G alpha (12/13) signalling events R-HSA-416482
RHOA GTPase cycle R-HSA-8980692
RHOBTB1 GTPase cycle R-HSA-9013422
Infectious disease R-HSA-5663205
Axon guidance R-HSA-422475
Sema4D in semaphorin signaling R-HSA-400685
SARS-CoV Infections R-HSA-9679506
EPHB-mediated forward signaling R-HSA-3928662
Disease R-HSA-1643685
Potential therapeutics for SARS R-HSA-9679191
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPH-Ephrin signaling R-HSA-2682334
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases R-HSA-194315
RHOC GTPase cycle R-HSA-9013106
RHO GTPases Activate ROCKs R-HSA-5627117
RHOBTB GTPase Cycle R-HSA-9706574
GPCR downstream signalling R-HSA-388396
VEGFA-VEGFR2 Pathway R-HSA-4420097
RHO GTPase Effectors R-HSA-195258
RHOH GTPase cycle R-HSA-9013407
Signaling by GPCR R-HSA-372790
Nervous system development R-HSA-9675108
Signaling by VEGF R-HSA-194138
RHOH GTPase cycle R-HSA-9013407
RHOBTB GTPase Cycle R-HSA-9706574
RHOA GTPase cycle R-HSA-8980692
RHOC GTPase cycle R-HSA-9013106
Semaphorin interactions R-HSA-373755
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
EPHB-mediated forward signaling R-HSA-3928662
Developmental Biology R-HSA-1266738
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
RHOB GTPase cycle R-HSA-9013026
Nervous system development R-HSA-9675108
GPCR downstream signalling R-HSA-388396
SARS-CoV Infections R-HSA-9679506
RHO GTPase Effectors R-HSA-195258
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
G alpha (12/13) signalling events R-HSA-416482
Sema4D in semaphorin signaling R-HSA-400685
Potential therapeutics for SARS R-HSA-9679191
RHO GTPase cycle R-HSA-9012999
Axon guidance R-HSA-422475
EPH-Ephrin signaling R-HSA-2682334
Infectious disease R-HSA-5663205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHOBTB1 GTPase cycle R-HSA-9013422
RHO GTPases Activate ROCKs R-HSA-5627117
Disease R-HSA-1643685
EPHA-mediated growth cone collapse R-HSA-3928663
RHOB GTPase cycle R-HSA-9013026
Signal Transduction R-HSA-162582
RHOBTB1 GTPase cycle R-HSA-9013422
RHOH GTPase cycle R-HSA-9013407
Semaphorin interactions R-HSA-373755
Signaling by GPCR R-HSA-372790
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHO GTPase Effectors R-HSA-195258
Signaling by VEGF R-HSA-194138
EPH-Ephrin signaling R-HSA-2682334
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Signaling by Rho GTPases R-HSA-194315
RHOBTB GTPase Cycle R-HSA-9706574
Developmental Biology R-HSA-1266738
GPCR downstream signalling R-HSA-388396
Sema4D in semaphorin signaling R-HSA-400685
VEGFA-VEGFR2 Pathway R-HSA-4420097
RHOA GTPase cycle R-HSA-8980692
SARS-CoV Infections R-HSA-9679506
RHOC GTPase cycle R-HSA-9013106
EPHB-mediated forward signaling R-HSA-3928662
RHO GTPases Activate ROCKs R-HSA-5627117
Potential therapeutics for SARS R-HSA-9679191
Disease R-HSA-1643685
G alpha (12/13) signalling events R-HSA-416482
Infectious disease R-HSA-5663205
RHO GTPase cycle R-HSA-9012999
Axon guidance R-HSA-422475
EPHA-mediated growth cone collapse R-HSA-3928663
Nervous system development R-HSA-9675108
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Sema4D in semaphorin signaling R-HSA-400685
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases R-HSA-194315
RHO GTPases Activate ROCKs R-HSA-5627117
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Signaling by GPCR R-HSA-372790
Disease R-HSA-1643685
Potential therapeutics for SARS R-HSA-9679191
RHOBTB GTPase Cycle R-HSA-9706574
RHOB GTPase cycle R-HSA-9013026
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase cycle R-HSA-9012999
G alpha (12/13) signalling events R-HSA-416482
RHOBTB1 GTPase cycle R-HSA-9013422
Infectious disease R-HSA-5663205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFA-VEGFR2 Pathway R-HSA-4420097
RHOC GTPase cycle R-HSA-9013106
RHOA GTPase cycle R-HSA-8980692
Nervous system development R-HSA-9675108
EPHA-mediated growth cone collapse R-HSA-3928663
Semaphorin interactions R-HSA-373755
RHO GTPase Effectors R-HSA-195258
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
RHOH GTPase cycle R-HSA-9013407
Axon guidance R-HSA-422475
EPHB-mediated forward signaling R-HSA-3928662
SARS-CoV Infections R-HSA-9679506
GPCR downstream signalling R-HSA-388396
EPH-Ephrin signaling R-HSA-2682334
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
EPHA-mediated growth cone collapse R-HSA-3928663
RHO GTPases Activate ROCKs R-HSA-5627117
Axon guidance R-HSA-422475
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
EPHB-mediated forward signaling R-HSA-3928662
RHO GTPase cycle R-HSA-9012999
RHOA GTPase cycle R-HSA-8980692
GPCR downstream signalling R-HSA-388396
Nervous system development R-HSA-9675108
VEGFA-VEGFR2 Pathway R-HSA-4420097
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
RHOBTB1 GTPase cycle R-HSA-9013422
EPH-Ephrin signaling R-HSA-2682334
RHO GTPase Effectors R-HSA-195258
Signaling by GPCR R-HSA-372790
RHOB GTPase cycle R-HSA-9013026
Potential therapeutics for SARS R-HSA-9679191
RHOBTB GTPase Cycle R-HSA-9706574
RHOH GTPase cycle R-HSA-9013407
SARS-CoV Infections R-HSA-9679506
Semaphorin interactions R-HSA-373755
RHOC GTPase cycle R-HSA-9013106
Sema4D in semaphorin signaling R-HSA-400685
Infectious disease R-HSA-5663205
G alpha (12/13) signalling events R-HSA-416482
RHO GTPase Effectors R-HSA-195258
SARS-CoV Infections R-HSA-9679506
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHOB GTPase cycle R-HSA-9013026
Signaling by VEGF R-HSA-194138
RHOC GTPase cycle R-HSA-9013106
RHOBTB GTPase Cycle R-HSA-9706574
EPHB-mediated forward signaling R-HSA-3928662
RHOH GTPase cycle R-HSA-9013407
Nervous system development R-HSA-9675108
RHOBTB1 GTPase cycle R-HSA-9013422
RHOA GTPase cycle R-HSA-8980692
G alpha (12/13) signalling events R-HSA-416482
GPCR downstream signalling R-HSA-388396
Signaling by Rho GTPases R-HSA-194315
VEGFA-VEGFR2 Pathway R-HSA-4420097
Axon guidance R-HSA-422475
Potential therapeutics for SARS R-HSA-9679191
RHO GTPases Activate ROCKs R-HSA-5627117
EPHA-mediated growth cone collapse R-HSA-3928663
Signaling by GPCR R-HSA-372790
Sema4D in semaphorin signaling R-HSA-400685
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase cycle R-HSA-9012999
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPH-Ephrin signaling R-HSA-2682334
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Semaphorin interactions R-HSA-373755

Expression Atlas ENSG00000134318
NCBI gene (formerly Entrezgene) 9475
GeneCards 10252
HGNC Symbol HGNC:10252
MIM gene 604002
UniProtKB Gene Name O75116
WikiGene 9475
Gene: MKNK1
Ensembl ID : ENSG00000079277
Description: MAPK interacting serine/threonine kinase 1
Gene Synonyms: MNK1
1 APIs:
168 Possible Orthologues:

Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by FGFR4 R-HSA-5654743
Spry regulation of FGF signaling R-HSA-1295596
Negative regulation of FGFR4 signaling R-HSA-5654733
Negative regulation of FGFR2 signaling R-HSA-5654727
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by FGFR1 R-HSA-5654736
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR R-HSA-190236
Signal Transduction R-HSA-162582
Signaling by FGFR3 R-HSA-5654741
Signaling by FGFR3 R-HSA-5654741
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FGFR4 R-HSA-5654743
Signaling by FGFR R-HSA-190236
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR1 R-HSA-5654736
Signal Transduction R-HSA-162582
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR2 R-HSA-5654738
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by FGFR3 R-HSA-5654741
Signaling by FGFR1 R-HSA-5654736
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR R-HSA-190236
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FGFR2 R-HSA-5654738
Negative regulation of FGFR3 signaling R-HSA-5654732
Spry regulation of FGF signaling R-HSA-1295596
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of FGFR1 signaling R-HSA-5654726
Signal Transduction R-HSA-162582
Signaling by FGFR4 R-HSA-5654743
Signal Transduction R-HSA-162582
Signaling by FGFR2 R-HSA-5654738
Spry regulation of FGF signaling R-HSA-1295596
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR1 R-HSA-5654736
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by FGFR R-HSA-190236
Negative regulation of FGFR2 signaling R-HSA-5654727
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by FGFR3 R-HSA-5654741
Signaling by FGFR4 R-HSA-5654743
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FGFR2 R-HSA-5654738
Signal Transduction R-HSA-162582
Signaling by FGFR3 R-HSA-5654741
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR4 R-HSA-5654743
Signaling by FGFR1 R-HSA-5654736
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of FGFR1 signaling R-HSA-5654726
Negative regulation of FGFR3 signaling R-HSA-5654732
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR R-HSA-190236
Signaling by FGFR1 R-HSA-5654736
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR2 R-HSA-5654738
Negative regulation of FGFR1 signaling R-HSA-5654726
Negative regulation of FGFR2 signaling R-HSA-5654727
Spry regulation of FGF signaling R-HSA-1295596
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by FGFR3 R-HSA-5654741
Signaling by FGFR4 R-HSA-5654743
Signaling by FGFR R-HSA-190236
Signal Transduction R-HSA-162582
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR R-HSA-190236
Signaling by FGFR1 R-HSA-5654736
Signaling by FGFR3 R-HSA-5654741
Negative regulation of FGFR2 signaling R-HSA-5654727
Signal Transduction R-HSA-162582
Signaling by FGFR4 R-HSA-5654743
Spry regulation of FGF signaling R-HSA-1295596
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FGFR2 R-HSA-5654738
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by FGFR2 R-HSA-5654738
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FGFR R-HSA-190236
Negative regulation of FGFR1 signaling R-HSA-5654726
Signal Transduction R-HSA-162582
Signaling by FGFR3 R-HSA-5654741
Signaling by FGFR1 R-HSA-5654736
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR4 R-HSA-5654743
Spry regulation of FGF signaling R-HSA-1295596
Spry regulation of FGF signaling R-HSA-1295596
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR3 R-HSA-5654741
Signaling by FGFR2 R-HSA-5654738
Signal Transduction R-HSA-162582
Signaling by FGFR1 R-HSA-5654736
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by FGFR R-HSA-190236
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FGFR4 R-HSA-5654743
Negative regulation of FGFR1 signaling R-HSA-5654726

Expression Atlas ENSG00000079277
NCBI gene (formerly Entrezgene) 8569
GeneCards 7110
HGNC Symbol HGNC:7110
MIM gene 606724
UniProtKB Gene Name Q9BUB5
WikiGene 8569
Gene: EGFR
Ensembl ID : ENSG00000146648
Description: epidermal growth factor receptor
Gene Synonyms: ERBB,ERBB1,ERRP
73 APIs:
286 Possible Orthologues:

Disease R-HSA-1643685
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
Downregulation of ERBB2 signaling R-HSA-8863795
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
Signaling by ERBB2 ECD mutants R-HSA-9665348
L1CAM interactions R-HSA-373760
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
HCMV Early Events R-HSA-9609690
GRB2 events in EGFR signaling R-HSA-179812
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PIP3 activates AKT signaling R-HSA-1257604
Membrane Trafficking R-HSA-199991
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
PI3K events in ERBB2 signaling R-HSA-1963642
Gene expression (Transcription) R-HSA-74160
EGFR interacts with phospholipase C-gamma R-HSA-212718
Signaling by Nuclear Receptors R-HSA-9006931
ESR-mediated signaling R-HSA-8939211
Developmental Biology R-HSA-1266738
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Intracellular signaling by second messengers R-HSA-9006925
Signal transduction by L1 R-HSA-445144
Extra-nuclear estrogen signaling R-HSA-9009391
Nervous system development R-HSA-9675108
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Signaling by PTK6 R-HSA-8848021
EGFR Transactivation by Gastrin R-HSA-2179392
G alpha (q) signalling events R-HSA-416476
Axon guidance R-HSA-422475
HCMV Infection R-HSA-9609646
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by EGFRvIII in Cancer R-HSA-5637812
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by GPCR R-HSA-372790
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Signal Transduction R-HSA-162582
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by ERBB2 in Cancer R-HSA-1227990
ERBB2 Regulates Cell Motility R-HSA-6785631
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by ERBB4 R-HSA-1236394
RNA Polymerase II Transcription R-HSA-73857
Signaling by EGFR in Cancer R-HSA-1643713
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB2 KD Mutants R-HSA-9664565
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by NOTCH3 R-HSA-9012852
PTK6 promotes HIF1A stabilization R-HSA-8857538
GPCR downstream signalling R-HSA-388396
Infectious disease R-HSA-5663205
SHC1 events in ERBB2 signaling R-HSA-1250196
SHC1 events in EGFR signaling R-HSA-180336
Vesicle-mediated transport R-HSA-5653656
GAB1 signalosome R-HSA-180292
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
PLCG1 events in ERBB2 signaling R-HSA-1251932
EGFR downregulation R-HSA-182971
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by ERBB2 R-HSA-1227986
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by EGFR R-HSA-177929
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by NOTCH R-HSA-157118
Generic Transcription Pathway R-HSA-212436
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SHC1 events in ERBB2 signaling R-HSA-1250196
EGFR interacts with phospholipase C-gamma R-HSA-212718
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by ERBB2 R-HSA-1227986
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by PTK6 R-HSA-8848021
GPCR downstream signalling R-HSA-388396
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
PI3K/AKT Signaling in Cancer R-HSA-2219528
Developmental Biology R-HSA-1266738
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by NOTCH R-HSA-157118
PIP3 activates AKT signaling R-HSA-1257604
Signal transduction by L1 R-HSA-445144
Membrane Trafficking R-HSA-199991
Signaling by ERBB4 R-HSA-1236394
Signaling by EGFRvIII in Cancer R-HSA-5637812
Vesicle-mediated transport R-HSA-5653656
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
L1CAM interactions R-HSA-373760
EGFR Transactivation by Gastrin R-HSA-2179392
Signaling by Nuclear Receptors R-HSA-9006931
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
ESR-mediated signaling R-HSA-8939211
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
HCMV Infection R-HSA-9609646
Signaling by ERBB2 in Cancer R-HSA-1227990
RNA Polymerase II Transcription R-HSA-73857
Signaling by EGFR R-HSA-177929
Signaling by GPCR R-HSA-372790
Axon guidance R-HSA-422475
GRB2 events in ERBB2 signaling R-HSA-1963640
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Infectious disease R-HSA-5663205
Signaling by NOTCH3 R-HSA-9012852
G alpha (q) signalling events R-HSA-416476
MAPK1/MAPK3 signaling R-HSA-5684996
Clathrin-mediated endocytosis R-HSA-8856828
Constitutive Signaling by EGFRvIII R-HSA-5637810
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
EGFR downregulation R-HSA-182971
GAB1 signalosome R-HSA-180292
GRB2 events in EGFR signaling R-HSA-179812
Downregulation of ERBB2 signaling R-HSA-8863795
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Nervous system development R-HSA-9675108
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Extra-nuclear estrogen signaling R-HSA-9009391
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ERBB2 ECD mutants R-HSA-9665348
PTK6 promotes HIF1A stabilization R-HSA-8857538
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
HCMV Early Events R-HSA-9609690
SHC1 events in EGFR signaling R-HSA-180336
PLCG1 events in ERBB2 signaling R-HSA-1251932
Signaling by ERBB2 KD Mutants R-HSA-9664565
Constitutive Signaling by EGFRvIII R-HSA-5637810
Infectious disease R-HSA-5663205
Signaling by Nuclear Receptors R-HSA-9006931
EGFR Transactivation by Gastrin R-HSA-2179392
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
SHC1 events in ERBB2 signaling R-HSA-1250196
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
ERBB2 Activates PTK6 Signaling R-HSA-8847993
PLCG1 events in ERBB2 signaling R-HSA-1251932
L1CAM interactions R-HSA-373760
EGFR downregulation R-HSA-182971
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by EGFR R-HSA-177929
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by EGFRvIII in Cancer R-HSA-5637812
Axon guidance R-HSA-422475
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
GRB2 events in EGFR signaling R-HSA-179812
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
ESR-mediated signaling R-HSA-8939211
RNA Polymerase II Transcription R-HSA-73857
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by EGFR in Cancer R-HSA-1643713
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by ERBB4 R-HSA-1236394
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Downregulation of ERBB2 signaling R-HSA-8863795
Vesicle-mediated transport R-HSA-5653656
GPCR downstream signalling R-HSA-388396
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
Signaling by PTK6 R-HSA-8848021
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
ERBB2 Regulates Cell Motility R-HSA-6785631
Generic Transcription Pathway R-HSA-212436
HCMV Early Events R-HSA-9609690
Signaling by NOTCH R-HSA-157118
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Developmental Biology R-HSA-1266738
Signal transduction by L1 R-HSA-445144
GRB2 events in ERBB2 signaling R-HSA-1963640
MAPK family signaling cascades R-HSA-5683057
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
RAF/MAP kinase cascade R-HSA-5673001
Signaling by ERBB2 ECD mutants R-HSA-9665348
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K events in ERBB2 signaling R-HSA-1963642
Gene expression (Transcription) R-HSA-74160
Membrane Trafficking R-HSA-199991
GAB1 signalosome R-HSA-180292
SHC1 events in EGFR signaling R-HSA-180336
Signaling by ERBB2 R-HSA-1227986
EGFR interacts with phospholipase C-gamma R-HSA-212718
Extra-nuclear estrogen signaling R-HSA-9009391
HCMV Infection R-HSA-9609646
MAPK1/MAPK3 signaling R-HSA-5684996
PTK6 promotes HIF1A stabilization R-HSA-8857538
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by EGFR in Cancer R-HSA-1643713
Constitutive Signaling by EGFRvIII R-HSA-5637810
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Infectious disease R-HSA-5663205
Signaling by GPCR R-HSA-372790
Signaling by ERBB2 KD Mutants R-HSA-9664565
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by EGFRvIII in Cancer R-HSA-5637812
G alpha (q) signalling events R-HSA-416476
Axon guidance R-HSA-422475
Vesicle-mediated transport R-HSA-5653656
HCMV Early Events R-HSA-9609690
Signaling by ERBB4 R-HSA-1236394
Signaling by EGFR R-HSA-177929
L1CAM interactions R-HSA-373760
GRB2 events in EGFR signaling R-HSA-179812
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH3 R-HSA-9012852
Disease R-HSA-1643685
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
GAB1 signalosome R-HSA-180292
SHC1 events in EGFR signaling R-HSA-180336
Signaling by PTK6 R-HSA-8848021
PLCG1 events in ERBB2 signaling R-HSA-1251932
PTK6 promotes HIF1A stabilization R-HSA-8857538
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH R-HSA-157118
Signal transduction by L1 R-HSA-445144
SHC1 events in ERBB2 signaling R-HSA-1250196
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by ERBB2 ECD mutants R-HSA-9665348
Intracellular signaling by second messengers R-HSA-9006925
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Membrane Trafficking R-HSA-199991
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
ERBB2 Regulates Cell Motility R-HSA-6785631
Generic Transcription Pathway R-HSA-212436
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by ERBB2 R-HSA-1227986
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Extra-nuclear estrogen signaling R-HSA-9009391
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Downregulation of ERBB2 signaling R-HSA-8863795
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EGFR downregulation R-HSA-182971
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI3K events in ERBB2 signaling R-HSA-1963642
EGFR interacts with phospholipase C-gamma R-HSA-212718
Signaling by Nuclear Receptors R-HSA-9006931
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
GPCR downstream signalling R-HSA-388396
ESR-mediated signaling R-HSA-8939211
EGFR Transactivation by Gastrin R-HSA-2179392
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
HCMV Infection R-HSA-9609646
Signaling by ERBB2 in Cancer R-HSA-1227990
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Vesicle-mediated transport R-HSA-5653656
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SHC1 events in EGFR signaling R-HSA-180336
ERBB2 Regulates Cell Motility R-HSA-6785631
RNA Polymerase II Transcription R-HSA-73857
PI3K/AKT Signaling in Cancer R-HSA-2219528
Generic Transcription Pathway R-HSA-212436
Signaling by ERBB2 ECD mutants R-HSA-9665348
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Signal Transduction R-HSA-162582
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
PLCG1 events in ERBB2 signaling R-HSA-1251932
GAB1 signalosome R-HSA-180292
HCMV Early Events R-HSA-9609690
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by Nuclear Receptors R-HSA-9006931
SHC1 events in ERBB2 signaling R-HSA-1250196
G alpha (q) signalling events R-HSA-416476
Signaling by PTK6 R-HSA-8848021
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signal transduction by L1 R-HSA-445144
Signaling by GPCR R-HSA-372790
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
PTK6 promotes HIF1A stabilization R-HSA-8857538
L1CAM interactions R-HSA-373760
Signaling by NOTCH R-HSA-157118
PI3K events in ERBB2 signaling R-HSA-1963642
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Infectious disease R-HSA-5663205
Signaling by EGFR in Cancer R-HSA-1643713
Disease R-HSA-1643685
ESR-mediated signaling R-HSA-8939211
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by EGFR R-HSA-177929
EGFR downregulation R-HSA-182971
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Developmental Biology R-HSA-1266738
EGFR Transactivation by Gastrin R-HSA-2179392
Intracellular signaling by second messengers R-HSA-9006925
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by ERBB2 KD Mutants R-HSA-9664565
Membrane Trafficking R-HSA-199991
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Extra-nuclear estrogen signaling R-HSA-9009391
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
GRB2 events in EGFR signaling R-HSA-179812
Signaling by ERBB4 R-HSA-1236394
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by EGFRvIII in Cancer R-HSA-5637812
Gene expression (Transcription) R-HSA-74160
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Downregulation of ERBB2 signaling R-HSA-8863795
Signaling by NOTCH3 R-HSA-9012852
Signaling by ERBB2 R-HSA-1227986
EGFR interacts with phospholipase C-gamma R-HSA-212718
HCMV Infection R-HSA-9609646
GPCR downstream signalling R-HSA-388396
Constitutive Signaling by EGFRvIII R-HSA-5637810
Axon guidance R-HSA-422475
EGFR interacts with phospholipase C-gamma R-HSA-212718
G alpha (q) signalling events R-HSA-416476
Signaling by ERBB4 R-HSA-1236394
SHC1 events in ERBB2 signaling R-HSA-1250196
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by Nuclear Receptors R-HSA-9006931
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Signaling by ERBB2 ECD mutants R-HSA-9665348
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by EGFR R-HSA-177929
Signaling by ERBB2 KD Mutants R-HSA-9664565
RAF/MAP kinase cascade R-HSA-5673001
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
GRB2 events in ERBB2 signaling R-HSA-1963640
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by ERBB2 R-HSA-1227986
ERBB2 Activates PTK6 Signaling R-HSA-8847993
PLCG1 events in ERBB2 signaling R-HSA-1251932
HCMV Early Events R-HSA-9609690
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PTK6 promotes HIF1A stabilization R-HSA-8857538
Signaling by ERBB2 in Cancer R-HSA-1227990
Signal transduction by L1 R-HSA-445144
ERBB2 Regulates Cell Motility R-HSA-6785631
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
GRB2 events in EGFR signaling R-HSA-179812
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Generic Transcription Pathway R-HSA-212436
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Axon guidance R-HSA-422475
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
ESR-mediated signaling R-HSA-8939211
Signaling by NOTCH R-HSA-157118
Signaling by EGFRvIII in Cancer R-HSA-5637812
Developmental Biology R-HSA-1266738
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by GPCR R-HSA-372790
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by PTK6 R-HSA-8848021
PI3K events in ERBB2 signaling R-HSA-1963642
Infectious disease R-HSA-5663205
L1CAM interactions R-HSA-373760
EGFR downregulation R-HSA-182971
EGFR Transactivation by Gastrin R-HSA-2179392
SHC1 events in EGFR signaling R-HSA-180336
Membrane Trafficking R-HSA-199991
Vesicle-mediated transport R-HSA-5653656
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Constitutive Signaling by EGFRvIII R-HSA-5637810
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by NOTCH3 R-HSA-9012852
Downregulation of ERBB2 signaling R-HSA-8863795
GAB1 signalosome R-HSA-180292
GPCR downstream signalling R-HSA-388396
HCMV Infection R-HSA-9609646
Signaling by Nuclear Receptors R-HSA-9006931
MAPK family signaling cascades R-HSA-5683057
ESR-mediated signaling R-HSA-8939211
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signaling by ERBB2 R-HSA-1227986
Signaling by NOTCH3 R-HSA-9012852
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by EGFR in Cancer R-HSA-1643713
HCMV Infection R-HSA-9609646
Membrane Trafficking R-HSA-199991
ERBB2 Regulates Cell Motility R-HSA-6785631
PI3K/AKT Signaling in Cancer R-HSA-2219528
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
SHC1 events in ERBB2 signaling R-HSA-1250196
PTK6 promotes HIF1A stabilization R-HSA-8857538
Signaling by NOTCH R-HSA-157118
GRB2 events in EGFR signaling R-HSA-179812
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Vesicle-mediated transport R-HSA-5653656
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by ERBB2 in Cancer R-HSA-1227990
Constitutive Signaling by EGFRvIII R-HSA-5637810
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
G alpha (q) signalling events R-HSA-416476
Generic Transcription Pathway R-HSA-212436
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Signal Transduction R-HSA-162582
L1CAM interactions R-HSA-373760
EGFR downregulation R-HSA-182971
Extra-nuclear estrogen signaling R-HSA-9009391
PI3K events in ERBB2 signaling R-HSA-1963642
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by EGFRvIII in Cancer R-HSA-5637812
Disease R-HSA-1643685
SHC1 events in EGFR signaling R-HSA-180336
Signaling by GPCR R-HSA-372790
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EGFR interacts with phospholipase C-gamma R-HSA-212718
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by PTK6 R-HSA-8848021
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
GRB2 events in ERBB2 signaling R-HSA-1963640
Clathrin-mediated endocytosis R-HSA-8856828
GAB1 signalosome R-HSA-180292
Downregulation of ERBB2 signaling R-HSA-8863795
PLCG1 events in ERBB2 signaling R-HSA-1251932
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by EGFR R-HSA-177929
GPCR downstream signalling R-HSA-388396
EGFR Transactivation by Gastrin R-HSA-2179392
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
Signal transduction by L1 R-HSA-445144
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
HCMV Early Events R-HSA-9609690
Signaling by ERBB4 R-HSA-1236394
Negative regulation of the PI3K/AKT network R-HSA-199418
Downregulation of ERBB2 signaling R-HSA-8863795
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K events in ERBB2 signaling R-HSA-1963642
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by EGFR R-HSA-177929
PTK6 promotes HIF1A stabilization R-HSA-8857538
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
GAB1 signalosome R-HSA-180292
RNA Polymerase II Transcription R-HSA-73857
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by ERBB4 R-HSA-1236394
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by EGFRvIII in Cancer R-HSA-5637812
Signaling by GPCR R-HSA-372790
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
GPCR downstream signalling R-HSA-388396
Signaling by EGFR in Cancer R-HSA-1643713
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH3 R-HSA-9012852
SHC1 events in ERBB2 signaling R-HSA-1250196
Signaling by ERBB2 in Cancer R-HSA-1227990
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal Transduction R-HSA-162582
Signaling by ERBB2 R-HSA-1227986
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Extra-nuclear estrogen signaling R-HSA-9009391
Generic Transcription Pathway R-HSA-212436
L1CAM interactions R-HSA-373760
Signaling by ERBB2 KD Mutants R-HSA-9664565
Nervous system development R-HSA-9675108
MAPK1/MAPK3 signaling R-HSA-5684996
EGFR downregulation R-HSA-182971
G alpha (q) signalling events R-HSA-416476
Signal transduction by L1 R-HSA-445144
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
GRB2 events in ERBB2 signaling R-HSA-1963640
Intracellular signaling by second messengers R-HSA-9006925
EGFR interacts with phospholipase C-gamma R-HSA-212718
RAF/MAP kinase cascade R-HSA-5673001
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
PLCG1 events in ERBB2 signaling R-HSA-1251932
GRB2 events in EGFR signaling R-HSA-179812
EGFR Transactivation by Gastrin R-HSA-2179392
HCMV Early Events R-HSA-9609690
SHC1 events in EGFR signaling R-HSA-180336
Signaling by NOTCH R-HSA-157118
MAPK family signaling cascades R-HSA-5683057
Signaling by PTK6 R-HSA-8848021
Clathrin-mediated endocytosis R-HSA-8856828
Disease R-HSA-1643685
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Membrane Trafficking R-HSA-199991
Axon guidance R-HSA-422475
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Vesicle-mediated transport R-HSA-5653656
HCMV Infection R-HSA-9609646
ESR-mediated signaling R-HSA-8939211
Intracellular signaling by second messengers R-HSA-9006925
Nervous system development R-HSA-9675108
EGFR Transactivation by Gastrin R-HSA-2179392
PLCG1 events in ERBB2 signaling R-HSA-1251932
Signal transduction by L1 R-HSA-445144
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
GPCR downstream signalling R-HSA-388396
HCMV Infection R-HSA-9609646
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
MAPK1/MAPK3 signaling R-HSA-5684996
PIP3 activates AKT signaling R-HSA-1257604
Signaling by PTK6 R-HSA-8848021
EGFR interacts with phospholipase C-gamma R-HSA-212718
HCMV Early Events R-HSA-9609690
EGFR downregulation R-HSA-182971
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by ERBB4 R-HSA-1236394
Axon guidance R-HSA-422475
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
PTK6 promotes HIF1A stabilization R-HSA-8857538
GRB2 events in EGFR signaling R-HSA-179812
MAPK family signaling cascades R-HSA-5683057
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
RNA Polymerase II Transcription R-HSA-73857
Clathrin-mediated endocytosis R-HSA-8856828
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Downregulation of ERBB2 signaling R-HSA-8863795
Signaling by EGFR R-HSA-177929
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Nuclear Receptors R-HSA-9006931
Generic Transcription Pathway R-HSA-212436
SHC1 events in EGFR signaling R-HSA-180336
Vesicle-mediated transport R-HSA-5653656
Signaling by EGFR in Cancer R-HSA-1643713
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by NOTCH R-HSA-157118
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB2 in Cancer R-HSA-1227990
ERBB2 Regulates Cell Motility R-HSA-6785631
ESR-mediated signaling R-HSA-8939211
L1CAM interactions R-HSA-373760
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by NOTCH3 R-HSA-9012852
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
GAB1 signalosome R-HSA-180292
Signaling by GPCR R-HSA-372790
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by ERBB2 R-HSA-1227986
Signaling by ERBB2 KD Mutants R-HSA-9664565
Disease R-HSA-1643685
SHC1 events in ERBB2 signaling R-HSA-1250196
Gene expression (Transcription) R-HSA-74160
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Membrane Trafficking R-HSA-199991
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by EGFRvIII in Cancer R-HSA-5637812
Extra-nuclear estrogen signaling R-HSA-9009391
Constitutive Signaling by EGFRvIII R-HSA-5637810
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Infectious disease R-HSA-5663205
Signaling by EGFRvIII in Cancer R-HSA-5637812
Signaling by EGFR in Cancer R-HSA-1643713
Intracellular signaling by second messengers R-HSA-9006925
Downregulation of ERBB2 signaling R-HSA-8863795
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by NOTCH R-HSA-157118
EGFR downregulation R-HSA-182971
GRB2 events in ERBB2 signaling R-HSA-1963640
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by ERBB2 in Cancer R-HSA-1227990
Infectious disease R-HSA-5663205
Signaling by ERBB2 R-HSA-1227986
Generic Transcription Pathway R-HSA-212436
Clathrin-mediated endocytosis R-HSA-8856828
RNA Polymerase II Transcription R-HSA-73857
Signaling by ERBB4 R-HSA-1236394
PTK6 promotes HIF1A stabilization R-HSA-8857538
SHC1 events in ERBB2 signaling R-HSA-1250196
Disease R-HSA-1643685
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
ERBB2 Regulates Cell Motility R-HSA-6785631
Gene expression (Transcription) R-HSA-74160
Vesicle-mediated transport R-HSA-5653656
Axon guidance R-HSA-422475
Signaling by PTK6 R-HSA-8848021
HCMV Infection R-HSA-9609646
MAPK family signaling cascades R-HSA-5683057
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
HCMV Early Events R-HSA-9609690
RAF/MAP kinase cascade R-HSA-5673001
EGFR interacts with phospholipase C-gamma R-HSA-212718
Membrane Trafficking R-HSA-199991
Constitutive Signaling by EGFRvIII R-HSA-5637810
PI3K events in ERBB2 signaling R-HSA-1963642
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
GAB1 signalosome R-HSA-180292
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signal transduction by L1 R-HSA-445144
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by GPCR R-HSA-372790
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
GPCR downstream signalling R-HSA-388396
Signaling by NOTCH3 R-HSA-9012852
Signal Transduction R-HSA-162582
EGFR Transactivation by Gastrin R-HSA-2179392
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
L1CAM interactions R-HSA-373760
Signaling by EGFR R-HSA-177929
G alpha (q) signalling events R-HSA-416476
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Negative regulation of the PI3K/AKT network R-HSA-199418
PLCG1 events in ERBB2 signaling R-HSA-1251932
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
GRB2 events in EGFR signaling R-HSA-179812
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
ESR-mediated signaling R-HSA-8939211
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SHC1 events in EGFR signaling R-HSA-180336

Expression Atlas ENSG00000146648
LRG display in Ensembl gene LRG_304
NCBI gene (formerly Entrezgene) 1956
GeneCards 3236
HGNC Symbol HGNC:3236
MIM gene 131550
MIM morbid 616069
UniProtKB Gene Name Q504U8
WikiGene 1956
Gene: EPHA3
Ensembl ID : ENSG00000044524
Description: EPH receptor A3
Gene Synonyms: ETK,ETK1,HEK,HEK4,TYRO4
1 APIs:
215 Possible Orthologues:

Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
EPH-Ephrin signaling R-HSA-2682334
EPHA-mediated growth cone collapse R-HSA-3928663
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
EPH-Ephrin signaling R-HSA-2682334
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
EPHA-mediated growth cone collapse R-HSA-3928663
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
EPH-ephrin mediated repulsion of cells R-HSA-3928665
EPHA-mediated growth cone collapse R-HSA-3928663
EPH-Ephrin signaling R-HSA-2682334
Nervous system development R-HSA-9675108
EPHA-mediated growth cone collapse R-HSA-3928663
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
EPH-Ephrin signaling R-HSA-2682334
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
EPHA-mediated growth cone collapse R-HSA-3928663
EPH-Ephrin signaling R-HSA-2682334
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
EPHA-mediated growth cone collapse R-HSA-3928663
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
EPH-Ephrin signaling R-HSA-2682334
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
EPH-Ephrin signaling R-HSA-2682334
EPHA-mediated growth cone collapse R-HSA-3928663
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Axon guidance R-HSA-422475
EPH-Ephrin signaling R-HSA-2682334
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
EPH-ephrin mediated repulsion of cells R-HSA-3928665
EPHA-mediated growth cone collapse R-HSA-3928663
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Nervous system development R-HSA-9675108
EPHA-mediated growth cone collapse R-HSA-3928663
EPH-Ephrin signaling R-HSA-2682334
EPHA-mediated growth cone collapse R-HSA-3928663
Developmental Biology R-HSA-1266738
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Axon guidance R-HSA-422475
EPH-Ephrin signaling R-HSA-2682334
Nervous system development R-HSA-9675108

Expression Atlas ENSG00000044524
NCBI gene (formerly Entrezgene) 2042
GeneCards 3387
HGNC Symbol HGNC:3387
MIM gene 179611
UniProtKB Gene Name P29320
WikiGene 2042
Gene: EML4
Ensembl ID : ENSG00000143924
Description: EMAP like 4
Gene Synonyms: C2ORF2,ELP120,ROPP120
5 APIs:
214 Possible Orthologues:

ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK in cancer R-HSA-9700206
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Mitotic Prometaphase R-HSA-68877
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
ALK mutants bind TKIs R-HSA-9700645
Disease R-HSA-1643685
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK fusions and activated point mutants R-HSA-9725370
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Cell Cycle R-HSA-1640170
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
M Phase R-HSA-68886
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Cell Cycle, Mitotic R-HSA-69278
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Mitotic Prometaphase R-HSA-68877
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
ALK mutants bind TKIs R-HSA-9700645
M Phase R-HSA-68886
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK in cancer R-HSA-9700206
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Cell Cycle, Mitotic R-HSA-69278
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
ALK mutants bind TKIs R-HSA-9700645
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Mitotic Prometaphase R-HSA-68877
Cell Cycle, Mitotic R-HSA-69278
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
ALK mutants bind TKIs R-HSA-9700645
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by ALK in cancer R-HSA-9700206
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Signaling by ALK in cancer R-HSA-9700206
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Disease R-HSA-1643685
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Cell Cycle R-HSA-1640170
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
M Phase R-HSA-68886

Expression Atlas ENSG00000143924
NCBI gene (formerly Entrezgene) 27436
GeneCards 1316
HGNC Symbol HGNC:1316
MIM gene 607442
UniProtKB Gene Name Q9HC35
WikiGene 27436
Gene: FLT4
Ensembl ID : ENSG00000037280
Description: fms related receptor tyrosine kinase 4
Gene Synonyms: PCL,VEGFR-3,VEGFR3
46 APIs:
198 Possible Orthologues:

Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by NOTCH4 R-HSA-9013694
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH R-HSA-157118
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by VEGF R-HSA-194138
Signaling by NOTCH R-HSA-157118
Signaling by VEGF R-HSA-194138
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signal Transduction R-HSA-162582
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by NOTCH4 R-HSA-9013694
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by VEGF R-HSA-194138
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
Signaling by VEGF R-HSA-194138
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH R-HSA-157118
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by NOTCH4 R-HSA-9013694
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH R-HSA-157118
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by VEGF R-HSA-194138
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by VEGF R-HSA-194138
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694

Expression Atlas ENSG00000037280
NCBI gene (formerly Entrezgene) 2324
GeneCards 3767
HGNC Symbol HGNC:3767
MIM gene 136352
MIM morbid 618780
UniProtKB Gene Name P35916
WikiGene 2324