Gene: LGALS3
Ensembl ID : ENSG00000131981
Description: galectin 3
Gene Synonyms: GALIG,LGALS2,MAC-2
3 APIs:
217 Possible Orthologues:

RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
Neutrophil degranulation R-HSA-6798695
Generic Transcription Pathway R-HSA-212436
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX1 R-HSA-8878171
Advanced glycosylation endproduct receptor signaling R-HSA-879415
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Innate Immune System R-HSA-168249
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333
Transcriptional regulation by RUNX1 R-HSA-8878171
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX2 R-HSA-8878166
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Neutrophil degranulation R-HSA-6798695
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX1 R-HSA-8878171
RNA Polymerase II Transcription R-HSA-73857
Neutrophil degranulation R-HSA-6798695
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
Generic Transcription Pathway R-HSA-212436
Innate Immune System R-HSA-168249
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Immune System R-HSA-168256
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333
Transcriptional regulation by RUNX2 R-HSA-8878166
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Immune System R-HSA-168256
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX1 R-HSA-8878171
Innate Immune System R-HSA-168249
Gene expression (Transcription) R-HSA-74160
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
Generic Transcription Pathway R-HSA-212436
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Generic Transcription Pathway R-HSA-212436
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333
RNA Polymerase II Transcription R-HSA-73857
Neutrophil degranulation R-HSA-6798695
Generic Transcription Pathway R-HSA-212436
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Transcriptional regulation by RUNX2 R-HSA-8878166
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Innate Immune System R-HSA-168249
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
RNA Polymerase II Transcription R-HSA-73857
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333
Transcriptional regulation by RUNX1 R-HSA-8878171
Transcriptional regulation by RUNX2 R-HSA-8878166
Gene expression (Transcription) R-HSA-74160
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Neutrophil degranulation R-HSA-6798695
Transcriptional regulation by RUNX1 R-HSA-8878171
Advanced glycosylation endproduct receptor signaling R-HSA-879415
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
Innate Immune System R-HSA-168249
RNA Polymerase II Transcription R-HSA-73857
Immune System R-HSA-168256
Transcriptional regulation by RUNX2 R-HSA-8878166
Neutrophil degranulation R-HSA-6798695
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256

Expression Atlas ENSG00000131981
NCBI gene (formerly Entrezgene) 3958
GeneCards 6563
HGNC Symbol HGNC:6563
MIM gene 153619
UniProtKB Gene Name P17931
WikiGene 3958
Gene: PSENEN
Ensembl ID : ENSG00000205155
Description: presenilin enhancer, gamma-secretase subunit
Gene Synonyms: PEN2
5 APIs:
185 Possible Orthologues:

Signaling by ERBB4 R-HSA-1236394
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH1 R-HSA-1980143
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
p75 NTR receptor-mediated signalling R-HSA-193704
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH4 R-HSA-9013694
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Regulated proteolysis of p75NTR R-HSA-193692
Amyloid fiber formation R-HSA-977225
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH2 R-HSA-1980145
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-Ephrin signaling R-HSA-2682334
Signaling by ERBB4 R-HSA-1236394
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulated proteolysis of p75NTR R-HSA-193692
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Developmental Biology R-HSA-1266738
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH2 R-HSA-1980145
Disease R-HSA-1643685
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 R-HSA-1980143
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Amyloid fiber formation R-HSA-977225
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH4 R-HSA-9013694
Noncanonical activation of NOTCH3 R-HSA-9017802
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Axon guidance R-HSA-422475
Metabolism of proteins R-HSA-392499
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
p75 NTR receptor-mediated signalling R-HSA-193704
Nervous system development R-HSA-9675108
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH2 R-HSA-1980145
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Noncanonical activation of NOTCH3 R-HSA-9017802
Death Receptor Signaling R-HSA-73887
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
Nervous system development R-HSA-9675108
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
Nuclear signaling by ERBB4 R-HSA-1251985
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 in Cancer R-HSA-2644603
NRIF signals cell death from the nucleus R-HSA-205043
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
p75 NTR receptor-mediated signalling R-HSA-193704
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH R-HSA-157118
Regulated proteolysis of p75NTR R-HSA-193692
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
EPH-Ephrin signaling R-HSA-2682334
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear signaling by ERBB4 R-HSA-1251985
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH3 R-HSA-9012852
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH2 R-HSA-1980145
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by ERBB4 R-HSA-1236394
Amyloid fiber formation R-HSA-977225
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Death Receptor Signaling R-HSA-73887
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by ERBB4 R-HSA-1236394
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH3 R-HSA-9012852
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Death Receptor Signaling R-HSA-73887
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Regulated proteolysis of p75NTR R-HSA-193692
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH4 R-HSA-9013694
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH2 R-HSA-1980145
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 R-HSA-1980143
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
EPH-Ephrin signaling R-HSA-2682334
Nuclear signaling by ERBB4 R-HSA-1251985
Nuclear signaling by ERBB4 R-HSA-1251985
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
Signaling by ERBB4 R-HSA-1236394
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH3 R-HSA-9012852
Disease R-HSA-1643685
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH4 R-HSA-9013694
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Nervous system development R-HSA-9675108
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Amyloid fiber formation R-HSA-977225
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH2 R-HSA-1980145
Axon guidance R-HSA-422475
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-Ephrin signaling R-HSA-2682334
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH R-HSA-157118
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH2 R-HSA-1980145
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH3 R-HSA-9012852
Noncanonical activation of NOTCH3 R-HSA-9017802
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nervous system development R-HSA-9675108
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Death Receptor Signaling R-HSA-73887
EPH-Ephrin signaling R-HSA-2682334
Metabolism of proteins R-HSA-392499
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Axon guidance R-HSA-422475
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NRIF signals cell death from the nucleus R-HSA-205043
Death Receptor Signaling R-HSA-73887
Disease R-HSA-1643685
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Amyloid fiber formation R-HSA-977225
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 in Cancer R-HSA-2644603
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH3 R-HSA-9012852
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signal Transduction R-HSA-162582
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by ERBB4 R-HSA-1236394
Metabolism of proteins R-HSA-392499
Signaling by NOTCH2 R-HSA-1980145
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 R-HSA-1980143
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Developmental Biology R-HSA-1266738
Noncanonical activation of NOTCH3 R-HSA-9017802
Nervous system development R-HSA-9675108
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Regulated proteolysis of p75NTR R-HSA-193692
Signal Transduction R-HSA-162582
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-Ephrin signaling R-HSA-2682334
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Death Receptor Signaling R-HSA-73887
Metabolism of proteins R-HSA-392499
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH3 R-HSA-9012852
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH R-HSA-157118
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Axon guidance R-HSA-422475
Signaling by NOTCH2 R-HSA-1980145
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 R-HSA-1980143
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 in Cancer R-HSA-2644603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by NOTCH1 in Cancer R-HSA-2644603
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
Death Receptor Signaling R-HSA-73887
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 R-HSA-1980143
Amyloid fiber formation R-HSA-977225
Disease R-HSA-1643685
Signaling by NOTCH2 R-HSA-1980145
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH3 R-HSA-9012852
Nervous system development R-HSA-9675108
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by ERBB4 R-HSA-1236394
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH4 R-HSA-9013694
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NRIF signals cell death from the nucleus R-HSA-205043
p75 NTR receptor-mediated signalling R-HSA-193704
EPH-Ephrin signaling R-HSA-2682334
Axon guidance R-HSA-422475
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Signaling by ERBB4 R-HSA-1236394
Nuclear signaling by ERBB4 R-HSA-1251985
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 in Cancer R-HSA-2644603
EPH-Ephrin signaling R-HSA-2682334
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
Disease R-HSA-1643685
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Amyloid fiber formation R-HSA-977225

Expression Atlas ENSG00000205155
LRG display in Ensembl gene LRG_222
NCBI gene (formerly Entrezgene) 55851
GeneCards 30100
HGNC Symbol HGNC:30100
MIM gene 607632
MIM morbid 613736
UniProtKB Gene Name Q9NZ42
WikiGene 55851
Gene: RPL17
Ensembl ID : ENSG00000265681
Description: ribosomal protein L17
Gene Synonyms: L17,RPL23
4 APIs:
159 Possible Orthologues:

Metabolism R-HSA-1430728
Metabolism of RNA R-HSA-8953854
Peptide chain elongation R-HSA-156902
Cellular responses to stress R-HSA-2262752
Formation of a pool of free 40S subunits R-HSA-72689
Eukaryotic Translation Initiation R-HSA-72613
Metabolism of proteins R-HSA-392499
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Disease R-HSA-1643685
Viral mRNA Translation R-HSA-192823
Cap-dependent Translation Initiation R-HSA-72737
Axon guidance R-HSA-422475
Metabolism R-HSA-1430728
Influenza Infection R-HSA-168255
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Influenza Viral RNA Transcription and Replication R-HSA-168273
Infectious disease R-HSA-5663205
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Selenocysteine synthesis R-HSA-2408557
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by ROBO receptors R-HSA-376176
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Cellular responses to stimuli R-HSA-8953897
rRNA processing R-HSA-72312
rRNA processing in the nucleus and cytosol R-HSA-8868773
Translation R-HSA-72766
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Selenoamino acid metabolism R-HSA-2408522
Cellular response to starvation R-HSA-9711097
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Eukaryotic Translation Termination R-HSA-72764
Nonsense-Mediated Decay (NMD) R-HSA-927802
Eukaryotic Translation Elongation R-HSA-156842
Selenoamino acid metabolism R-HSA-2408522
Viral mRNA Translation R-HSA-192823
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Eukaryotic Translation Elongation R-HSA-156842
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Nonsense-Mediated Decay (NMD) R-HSA-927802
Disease R-HSA-1643685
rRNA processing in the nucleus and cytosol R-HSA-8868773
Metabolism R-HSA-1430728
Translation R-HSA-72766
Metabolism of amino acids and derivatives R-HSA-71291
Cap-dependent Translation Initiation R-HSA-72737
Nervous system development R-HSA-9675108
Influenza Viral RNA Transcription and Replication R-HSA-168273
Metabolism of proteins R-HSA-392499
rRNA processing R-HSA-72312
Peptide chain elongation R-HSA-156902
Metabolism of RNA R-HSA-8953854
Developmental Biology R-HSA-1266738
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Influenza Infection R-HSA-168255
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
Selenocysteine synthesis R-HSA-2408557
Signaling by ROBO receptors R-HSA-376176
Eukaryotic Translation Termination R-HSA-72764
Formation of a pool of free 40S subunits R-HSA-72689
Eukaryotic Translation Initiation R-HSA-72613
Cellular response to starvation R-HSA-9711097
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Metabolism of amino acids and derivatives R-HSA-71291
Axon guidance R-HSA-422475
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Eukaryotic Translation Termination R-HSA-72764
Developmental Biology R-HSA-1266738
Formation of a pool of free 40S subunits R-HSA-72689
Metabolism R-HSA-1430728
Influenza Infection R-HSA-168255
Influenza Viral RNA Transcription and Replication R-HSA-168273
Translation R-HSA-72766
Cellular responses to stimuli R-HSA-8953897
Eukaryotic Translation Elongation R-HSA-156842
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
rRNA processing in the nucleus and cytosol R-HSA-8868773
Selenocysteine synthesis R-HSA-2408557
Metabolism of RNA R-HSA-8953854
Cellular responses to stress R-HSA-2262752
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
rRNA processing R-HSA-72312
Nervous system development R-HSA-9675108
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Cellular response to starvation R-HSA-9711097
Eukaryotic Translation Initiation R-HSA-72613
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Nonsense-Mediated Decay (NMD) R-HSA-927802
Viral mRNA Translation R-HSA-192823
Infectious disease R-HSA-5663205
Peptide chain elongation R-HSA-156902
Cap-dependent Translation Initiation R-HSA-72737
Signaling by ROBO receptors R-HSA-376176
Selenoamino acid metabolism R-HSA-2408522
Selenoamino acid metabolism R-HSA-2408522
Metabolism R-HSA-1430728
rRNA processing R-HSA-72312
Eukaryotic Translation Elongation R-HSA-156842
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Axon guidance R-HSA-422475
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Cellular responses to stimuli R-HSA-8953897
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Influenza Infection R-HSA-168255
rRNA processing in the nucleus and cytosol R-HSA-8868773
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Cellular response to starvation R-HSA-9711097
Nervous system development R-HSA-9675108
Influenza Viral RNA Transcription and Replication R-HSA-168273
Peptide chain elongation R-HSA-156902
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Metabolism of amino acids and derivatives R-HSA-71291
Cap-dependent Translation Initiation R-HSA-72737
Formation of a pool of free 40S subunits R-HSA-72689
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Viral mRNA Translation R-HSA-192823
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Nonsense-Mediated Decay (NMD) R-HSA-927802
Signaling by ROBO receptors R-HSA-376176
Eukaryotic Translation Initiation R-HSA-72613
Selenocysteine synthesis R-HSA-2408557
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Metabolism of proteins R-HSA-392499
Translation R-HSA-72766
Metabolism of RNA R-HSA-8953854
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Eukaryotic Translation Termination R-HSA-72764
Selenoamino acid metabolism R-HSA-2408522
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by ROBO receptors R-HSA-376176
Cellular response to starvation R-HSA-9711097
Nervous system development R-HSA-9675108
Eukaryotic Translation Termination R-HSA-72764
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Translation R-HSA-72766
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Metabolism R-HSA-1430728
Eukaryotic Translation Initiation R-HSA-72613
Developmental Biology R-HSA-1266738
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Peptide chain elongation R-HSA-156902
Influenza Infection R-HSA-168255
rRNA processing R-HSA-72312
Metabolism of RNA R-HSA-8953854
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Formation of a pool of free 40S subunits R-HSA-72689
Cellular responses to stress R-HSA-2262752
rRNA processing in the nucleus and cytosol R-HSA-8868773
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Metabolism of proteins R-HSA-392499
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Cap-dependent Translation Initiation R-HSA-72737
Nonsense-Mediated Decay (NMD) R-HSA-927802
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Cellular responses to stimuli R-HSA-8953897
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Eukaryotic Translation Elongation R-HSA-156842
Influenza Viral RNA Transcription and Replication R-HSA-168273
Infectious disease R-HSA-5663205
Viral mRNA Translation R-HSA-192823
Selenocysteine synthesis R-HSA-2408557
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Selenocysteine synthesis R-HSA-2408557
Cellular responses to stress R-HSA-2262752
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Nervous system development R-HSA-9675108
Metabolism of RNA R-HSA-8953854
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Selenoamino acid metabolism R-HSA-2408522
Metabolism of proteins R-HSA-392499
Nonsense-Mediated Decay (NMD) R-HSA-927802
Signaling by ROBO receptors R-HSA-376176
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Cap-dependent Translation Initiation R-HSA-72737
Eukaryotic Translation Termination R-HSA-72764
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Cellular responses to stimuli R-HSA-8953897
Axon guidance R-HSA-422475
Eukaryotic Translation Elongation R-HSA-156842
rRNA processing R-HSA-72312
Formation of a pool of free 40S subunits R-HSA-72689
Eukaryotic Translation Initiation R-HSA-72613
Influenza Infection R-HSA-168255
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Viral mRNA Translation R-HSA-192823
Cellular response to starvation R-HSA-9711097
Translation R-HSA-72766
rRNA processing in the nucleus and cytosol R-HSA-8868773
Influenza Viral RNA Transcription and Replication R-HSA-168273
Developmental Biology R-HSA-1266738
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Peptide chain elongation R-HSA-156902
Axon guidance R-HSA-422475
Selenocysteine synthesis R-HSA-2408557
Metabolism of proteins R-HSA-392499
Metabolism R-HSA-1430728
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Nonsense-Mediated Decay (NMD) R-HSA-927802
Developmental Biology R-HSA-1266738
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Viral mRNA Translation R-HSA-192823
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Selenoamino acid metabolism R-HSA-2408522
Formation of a pool of free 40S subunits R-HSA-72689
Cellular responses to stress R-HSA-2262752
Influenza Viral RNA Transcription and Replication R-HSA-168273
Metabolism of RNA R-HSA-8953854
Metabolism of amino acids and derivatives R-HSA-71291
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Influenza Infection R-HSA-168255
Eukaryotic Translation Elongation R-HSA-156842
Translation R-HSA-72766
Eukaryotic Translation Termination R-HSA-72764
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
rRNA processing in the nucleus and cytosol R-HSA-8868773
Cellular responses to stimuli R-HSA-8953897
Disease R-HSA-1643685
Cellular response to starvation R-HSA-9711097
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Cap-dependent Translation Initiation R-HSA-72737
rRNA processing R-HSA-72312
Infectious disease R-HSA-5663205
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Eukaryotic Translation Initiation R-HSA-72613
Peptide chain elongation R-HSA-156902
Signaling by ROBO receptors R-HSA-376176
Nervous system development R-HSA-9675108
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Viral mRNA Translation R-HSA-192823
Metabolism of amino acids and derivatives R-HSA-71291
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Disease R-HSA-1643685
Selenocysteine synthesis R-HSA-2408557
Developmental Biology R-HSA-1266738
Eukaryotic Translation Termination R-HSA-72764
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Cap-dependent Translation Initiation R-HSA-72737
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Influenza Viral RNA Transcription and Replication R-HSA-168273
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Infectious disease R-HSA-5663205
Cellular response to starvation R-HSA-9711097
rRNA processing R-HSA-72312
Translation R-HSA-72766
rRNA processing in the nucleus and cytosol R-HSA-8868773
Eukaryotic Translation Elongation R-HSA-156842
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Formation of a pool of free 40S subunits R-HSA-72689
Eukaryotic Translation Initiation R-HSA-72613
Nonsense-Mediated Decay (NMD) R-HSA-927802
Metabolism of RNA R-HSA-8953854
Signaling by ROBO receptors R-HSA-376176
Cellular responses to stress R-HSA-2262752
Influenza Infection R-HSA-168255
Peptide chain elongation R-HSA-156902
Metabolism of proteins R-HSA-392499
Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
Axon guidance R-HSA-422475
Selenoamino acid metabolism R-HSA-2408522
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Nervous system development R-HSA-9675108
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Eukaryotic Translation Initiation R-HSA-72613
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Nervous system development R-HSA-9675108
Eukaryotic Translation Elongation R-HSA-156842
Metabolism of RNA R-HSA-8953854
Formation of a pool of free 40S subunits R-HSA-72689
Peptide chain elongation R-HSA-156902
Cap-dependent Translation Initiation R-HSA-72737
Cellular responses to stimuli R-HSA-8953897
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Cellular response to starvation R-HSA-9711097
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
Translation R-HSA-72766
Selenocysteine synthesis R-HSA-2408557
Metabolism R-HSA-1430728
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Signaling by ROBO receptors R-HSA-376176
Developmental Biology R-HSA-1266738
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Nonsense-Mediated Decay (NMD) R-HSA-927802
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Influenza Infection R-HSA-168255
rRNA processing R-HSA-72312
rRNA processing in the nucleus and cytosol R-HSA-8868773
Metabolism of amino acids and derivatives R-HSA-71291
Infectious disease R-HSA-5663205
Viral mRNA Translation R-HSA-192823
Influenza Viral RNA Transcription and Replication R-HSA-168273
Eukaryotic Translation Termination R-HSA-72764
Selenoamino acid metabolism R-HSA-2408522
rRNA processing R-HSA-72312
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Cellular responses to stress R-HSA-2262752
Formation of a pool of free 40S subunits R-HSA-72689
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
rRNA processing in the nucleus and cytosol R-HSA-8868773
Influenza Viral RNA Transcription and Replication R-HSA-168273
Metabolism of proteins R-HSA-392499
Eukaryotic Translation Termination R-HSA-72764
Metabolism of amino acids and derivatives R-HSA-71291
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Disease R-HSA-1643685
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Translation R-HSA-72766
Signaling by ROBO receptors R-HSA-376176
Metabolism of RNA R-HSA-8953854
Infectious disease R-HSA-5663205
Peptide chain elongation R-HSA-156902
Selenoamino acid metabolism R-HSA-2408522
Axon guidance R-HSA-422475
Cap-dependent Translation Initiation R-HSA-72737
Nonsense-Mediated Decay (NMD) R-HSA-927802
Eukaryotic Translation Initiation R-HSA-72613
Cellular response to starvation R-HSA-9711097
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Cellular responses to stimuli R-HSA-8953897
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Influenza Infection R-HSA-168255
Eukaryotic Translation Elongation R-HSA-156842
Selenocysteine synthesis R-HSA-2408557
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Viral mRNA Translation R-HSA-192823
Cap-dependent Translation Initiation R-HSA-72737
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Nonsense-Mediated Decay (NMD) R-HSA-927802
Eukaryotic Translation Initiation R-HSA-72613
Viral mRNA Translation R-HSA-192823
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Disease R-HSA-1643685
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Selenocysteine synthesis R-HSA-2408557
Axon guidance R-HSA-422475
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Selenoamino acid metabolism R-HSA-2408522
Influenza Viral RNA Transcription and Replication R-HSA-168273
Developmental Biology R-HSA-1266738
rRNA processing in the nucleus and cytosol R-HSA-8868773
Eukaryotic Translation Termination R-HSA-72764
Peptide chain elongation R-HSA-156902
Translation R-HSA-72766
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Metabolism of proteins R-HSA-392499
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Infectious disease R-HSA-5663205
Metabolism of RNA R-HSA-8953854
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Eukaryotic Translation Elongation R-HSA-156842
Cellular responses to stress R-HSA-2262752
Cellular response to starvation R-HSA-9711097
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by ROBO receptors R-HSA-376176
rRNA processing R-HSA-72312
Formation of a pool of free 40S subunits R-HSA-72689
Nervous system development R-HSA-9675108
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Influenza Infection R-HSA-168255
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957

Expression Atlas ENSG00000265681
NCBI gene (formerly Entrezgene) 6139
GeneCards 10307
HGNC Symbol HGNC:10307
MIM gene 603661
UniProtKB Gene Name P18621
WikiGene 6139
Gene: PSMA2
Ensembl ID : ENSG00000106588
Description: proteasome 20S subunit alpha 2
Gene Synonyms: HC3,MU,PMSA2
6 APIs:
231 Possible Orthologues:

Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by NOTCH4 R-HSA-9013694
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Metabolism of proteins R-HSA-392499
Signaling by NOTCH R-HSA-157118
Regulation of Apoptosis R-HSA-169911
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of DVL R-HSA-4641258
Activation of NF-kappaB in B cells R-HSA-1169091
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stimuli R-HSA-8953897
ABC transporter disorders R-HSA-5619084
UCH proteinases R-HSA-5689603
Cellular responses to stress R-HSA-2262752
Regulation of PTEN stability and activity R-HSA-8948751
MAPK6/MAPK4 signaling R-HSA-5687128
Host Interactions of HIV factors R-HSA-162909
RAF/MAP kinase cascade R-HSA-5673001
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of GLI1 by the proteasome R-HSA-5610780
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Downstream TCR signaling R-HSA-202424
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of mitotic cell cycle R-HSA-453276
Innate Immune System R-HSA-168249
Ub-specific processing proteases R-HSA-5689880
Vpu mediated degradation of CD4 R-HSA-180534
G1/S DNA Damage Checkpoints R-HSA-69615
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
DNA Replication R-HSA-69306
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Hedgehog 'off' state R-HSA-5610787
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of GLI2 by the proteasome R-HSA-5610783
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FCERI mediated NF-kB activation R-HSA-2871837
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
Neddylation R-HSA-8951664
Adaptive Immune System R-HSA-1280218
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Synthesis of DNA R-HSA-69239
ER-Phagosome pathway R-HSA-1236974
Disorders of transmembrane transporters R-HSA-5619115
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of polyamines R-HSA-351202
Post-translational protein modification R-HSA-597592
Signaling by WNT R-HSA-195721
PIP3 activates AKT signaling R-HSA-1257604
S Phase R-HSA-69242
Assembly of the pre-replicative complex R-HSA-68867
Gene expression (Transcription) R-HSA-74160
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX3 expression and activity R-HSA-8941858
Neutrophil degranulation R-HSA-6798695
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Anaphase R-HSA-68882
Mitotic G2-G2/M phases R-HSA-453274
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX1 R-HSA-8878171
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
Metabolism of RNA R-HSA-8953854
Transport of small molecules R-HSA-382551
Degradation of AXIN R-HSA-4641257
G2/M Transition R-HSA-69275
Antigen processing-Cross presentation R-HSA-1236975
Programmed Cell Death R-HSA-5357801
PTEN Regulation R-HSA-6807070
Nuclear events mediated by NFE2L2 R-HSA-9759194
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
ABC-family proteins mediated transport R-HSA-382556
G1/S Transition R-HSA-69206
Class I MHC mediated antigen processing & presentation R-HSA-983169
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to hypoxia R-HSA-1234174
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
HIV Infection R-HSA-162906
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Hedgehog R-HSA-5358351
Hh mutants are degraded by ERAD R-HSA-5362768
Nervous system development R-HSA-9675108
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cellular response to chemical stress R-HSA-9711123
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
M Phase R-HSA-68886
Metabolism R-HSA-1430728
G2/M Checkpoints R-HSA-69481
Orc1 removal from chromatin R-HSA-68949
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'on' state R-HSA-5632684
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
DNA Replication Pre-Initiation R-HSA-69002
Stabilization of p53 R-HSA-69541
Axon guidance R-HSA-422475
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of amino acids and derivatives R-HSA-71291
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Deubiquitination R-HSA-5688426
Interleukin-1 family signaling R-HSA-446652
TCR signaling R-HSA-202403
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Separation of Sister Chromatids R-HSA-2467813
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of beta-catenin by the destruction complex R-HSA-195253
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of AXIN R-HSA-4641257
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Beta-catenin independent WNT signaling R-HSA-3858494
Post-translational protein modification R-HSA-597592
Axon guidance R-HSA-422475
Signaling by Hedgehog R-HSA-5358351
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Host Interactions of HIV factors R-HSA-162909
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cell Cycle R-HSA-1640170
TCF dependent signaling in response to WNT R-HSA-201681
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Vpu mediated degradation of CD4 R-HSA-180534
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Asymmetric localization of PCP proteins R-HSA-4608870
Neddylation R-HSA-8951664
p53-Independent DNA Damage Response R-HSA-69610
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of PTEN stability and activity R-HSA-8948751
G1/S DNA Damage Checkpoints R-HSA-69615
TCR signaling R-HSA-202403
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transport of small molecules R-HSA-382551
Metabolism of RNA R-HSA-8953854
ABC-family proteins mediated transport R-HSA-382556
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'off' state R-HSA-5610787
Signaling by WNT R-HSA-195721
Metabolism of amino acids and derivatives R-HSA-71291
Separation of Sister Chromatids R-HSA-2467813
Gene expression (Transcription) R-HSA-74160
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
Cellular response to hypoxia R-HSA-1234174
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle, Mitotic R-HSA-69278
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cytokine Signaling in Immune system R-HSA-1280215
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of beta-catenin by the destruction complex R-HSA-195253
DNA Replication R-HSA-69306
M Phase R-HSA-68886
Nuclear events mediated by NFE2L2 R-HSA-9759194
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of DVL R-HSA-4641258
Activation of NF-kappaB in B cells R-HSA-1169091
Innate Immune System R-HSA-168249
Apoptosis R-HSA-109581
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CLEC7A (Dectin-1) signaling R-HSA-5607764
S Phase R-HSA-69242
UCH proteinases R-HSA-5689603
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
FCERI mediated NF-kB activation R-HSA-2871837
PIP3 activates AKT signaling R-HSA-1257604
Downstream TCR signaling R-HSA-202424
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Synthesis of DNA R-HSA-69239
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
Orc1 removal from chromatin R-HSA-68949
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Metabolism of proteins R-HSA-392499
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Cellular responses to stress R-HSA-2262752
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
ABC transporter disorders R-HSA-5619084
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK family signaling cascades R-HSA-5683057
G2/M Transition R-HSA-69275
MAPK1/MAPK3 signaling R-HSA-5684996
PTEN Regulation R-HSA-6807070
Cellular responses to stimuli R-HSA-8953897
Mitotic Anaphase R-HSA-68882
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog 'on' state R-HSA-5632684
Vif-mediated degradation of APOBEC3G R-HSA-180585
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signal Transduction R-HSA-162582
Degradation of GLI1 by the proteasome R-HSA-5610780
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Interleukin-1 signaling R-HSA-9020702
DNA Replication Pre-Initiation R-HSA-69002
Neutrophil degranulation R-HSA-6798695
Ub-specific processing proteases R-HSA-5689880
Switching of origins to a post-replicative state R-HSA-69052
Nervous system development R-HSA-9675108
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
Cyclin E associated events during G1/S transition R-HSA-69202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
Deubiquitination R-HSA-5688426
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
PCP/CE pathway R-HSA-4086400
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle Checkpoints R-HSA-69620
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of polyamines R-HSA-351202
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by NOTCH R-HSA-157118
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
TCR signaling R-HSA-202403
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Beta-catenin independent WNT signaling R-HSA-3858494
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of RNA R-HSA-8953854
Separation of Sister Chromatids R-HSA-2467813
Adaptive Immune System R-HSA-1280218
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Infectious disease R-HSA-5663205
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Axon guidance R-HSA-422475
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by WNT R-HSA-195721
Metabolism of polyamines R-HSA-351202
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Developmental Biology R-HSA-1266738
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Neddylation R-HSA-8951664
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'off' state R-HSA-5610787
Metabolism of amino acids and derivatives R-HSA-71291
Disorders of transmembrane transporters R-HSA-5619115
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nuclear events mediated by NFE2L2 R-HSA-9759194
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Checkpoints R-HSA-69481
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of proteins R-HSA-392499
Cellular response to chemical stress R-HSA-9711123
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
Downstream TCR signaling R-HSA-202424
Mitotic G2-G2/M phases R-HSA-453274
Mitotic G1 phase and G1/S transition R-HSA-453279
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
HIV Infection R-HSA-162906
Transcriptional regulation by RUNX2 R-HSA-8878166
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of GLI2 by the proteasome R-HSA-5610783
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Synthesis of DNA R-HSA-69239
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transport of small molecules R-HSA-382551
Signaling by NOTCH4 R-HSA-9013694
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PTEN Regulation R-HSA-6807070
Post-translational protein modification R-HSA-597592
Intracellular signaling by second messengers R-HSA-9006925
CLEC7A (Dectin-1) signaling R-HSA-5607764
UCH proteinases R-HSA-5689603
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Defective CFTR causes cystic fibrosis R-HSA-5678895
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ABC-family proteins mediated transport R-HSA-382556
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of Apoptosis R-HSA-169911
S Phase R-HSA-69242
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 signaling R-HSA-9020702
DNA Replication R-HSA-69306
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of AXIN R-HSA-4641257
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
Cell Cycle, Mitotic R-HSA-69278
Assembly of the pre-replicative complex R-HSA-68867
Signal Transduction R-HSA-162582
PCP/CE pathway R-HSA-4086400
Regulation of RAS by GAPs R-HSA-5658442
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Programmed Cell Death R-HSA-5357801
Cellular response to hypoxia R-HSA-1234174
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH R-HSA-157118
ER-Phagosome pathway R-HSA-1236974
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Hedgehog R-HSA-5358351
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK1/MAPK3 signaling R-HSA-5684996
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cell Cycle Checkpoints R-HSA-69620
M Phase R-HSA-68886
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Gene expression (Transcription) R-HSA-74160
Neutrophil degranulation R-HSA-6798695
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
G1/S Transition R-HSA-69206
Class I MHC mediated antigen processing & presentation R-HSA-983169
RNA Polymerase II Transcription R-HSA-73857
MAPK6/MAPK4 signaling R-HSA-5687128
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX3 R-HSA-8878159
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by Interleukins R-HSA-449147
Degradation of DVL R-HSA-4641258
Vpu mediated degradation of CD4 R-HSA-180534
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
DNA Replication R-HSA-69306
Post-translational protein modification R-HSA-597592
TCF dependent signaling in response to WNT R-HSA-201681
Vpu mediated degradation of CD4 R-HSA-180534
ABC-family proteins mediated transport R-HSA-382556
Axon guidance R-HSA-422475
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Programmed Cell Death R-HSA-5357801
Asymmetric localization of PCP proteins R-HSA-4608870
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK6/MAPK4 signaling R-HSA-5687128
Deubiquitination R-HSA-5688426
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Infectious disease R-HSA-5663205
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX2 expression and activity R-HSA-8939902
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
Vif-mediated degradation of APOBEC3G R-HSA-180585
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by WNT R-HSA-195721
p53-Dependent G1 DNA Damage Response R-HSA-69563
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
Metabolism of RNA R-HSA-8953854
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S DNA Damage Checkpoints R-HSA-69615
ABC transporter disorders R-HSA-5619084
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Stabilization of p53 R-HSA-69541
MAPK1/MAPK3 signaling R-HSA-5684996
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Generic Transcription Pathway R-HSA-212436
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of PTEN stability and activity R-HSA-8948751
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular responses to stimuli R-HSA-8953897
Neutrophil degranulation R-HSA-6798695
Metabolism of polyamines R-HSA-351202
Cellular response to chemical stress R-HSA-9711123
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants are degraded by ERAD R-HSA-5362768
Hedgehog 'off' state R-HSA-5610787
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by ROBO receptors R-HSA-376176
Regulation of mitotic cell cycle R-HSA-453276
HIV Infection R-HSA-162906
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog ligand biogenesis R-HSA-5358346
Downstream TCR signaling R-HSA-202424
G1/S Transition R-HSA-69206
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX1 R-HSA-8878171
Cytokine Signaling in Immune system R-HSA-1280215
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog 'on' state R-HSA-5632684
Regulation of Apoptosis R-HSA-169911
Synthesis of DNA R-HSA-69239
TCR signaling R-HSA-202403
Metabolism of amino acids and derivatives R-HSA-71291
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G2-G2/M phases R-HSA-453274
Nervous system development R-HSA-9675108
Assembly of the pre-replicative complex R-HSA-68867
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
UCH proteinases R-HSA-5689603
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
Regulation of expression of SLITs and ROBOs R-HSA-9010553
S Phase R-HSA-69242
Mitotic Anaphase R-HSA-68882
M Phase R-HSA-68886
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Host Interactions of HIV factors R-HSA-162909
p53-Independent DNA Damage Response R-HSA-69610
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Disorders of transmembrane transporters R-HSA-5619115
PCP/CE pathway R-HSA-4086400
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Hedgehog R-HSA-5358351
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of AXIN R-HSA-4641257
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of DVL R-HSA-4641258
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transport of small molecules R-HSA-382551
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Switching of origins to a post-replicative state R-HSA-69052
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Separation of Sister Chromatids R-HSA-2467813
Cell Cycle, Mitotic R-HSA-69278
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 signaling R-HSA-9020702
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G1 phase and G1/S transition R-HSA-453279
FCERI mediated NF-kB activation R-HSA-2871837
Immune System R-HSA-168256
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH4 R-HSA-9013694
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH R-HSA-157118
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Orc1 removal from chromatin R-HSA-68949
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Orc1 removal from chromatin R-HSA-68949
G2/M Checkpoints R-HSA-69481
Separation of Sister Chromatids R-HSA-2467813
C-type lectin receptors (CLRs) R-HSA-5621481
S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Switching of origins to a post-replicative state R-HSA-69052
Synthesis of DNA R-HSA-69239
DNA Replication Pre-Initiation R-HSA-69002
PCP/CE pathway R-HSA-4086400
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Negative regulation of NOTCH4 signaling R-HSA-9604323
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Developmental Biology R-HSA-1266738
Signaling by Hedgehog R-HSA-5358351
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stimuli R-HSA-8953897
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Interleukins R-HSA-449147
Cellular response to chemical stress R-HSA-9711123
HIV Infection R-HSA-162906
TCR signaling R-HSA-202403
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle R-HSA-1640170
Signaling by WNT R-HSA-195721
p53-Dependent G1 DNA Damage Response R-HSA-69563
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Stabilization of p53 R-HSA-69541
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Regulation of Apoptosis R-HSA-169911
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RAS by GAPs R-HSA-5658442
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX2 R-HSA-8878166
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Immune System R-HSA-168256
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vpu mediated degradation of CD4 R-HSA-180534
Vif-mediated degradation of APOBEC3G R-HSA-180585
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic Metaphase and Anaphase R-HSA-2555396
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transport of small molecules R-HSA-382551
Intracellular signaling by second messengers R-HSA-9006925
Nuclear events mediated by NFE2L2 R-HSA-9759194
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
DNA Replication R-HSA-69306
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of polyamines R-HSA-351202
Neutrophil degranulation R-HSA-6798695
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ub-specific processing proteases R-HSA-5689880
Neddylation R-HSA-8951664
Cell Cycle Checkpoints R-HSA-69620
Mitotic Anaphase R-HSA-68882
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Programmed Cell Death R-HSA-5357801
Degradation of DVL R-HSA-4641258
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Post-translational protein modification R-HSA-597592
Regulation of mitotic cell cycle R-HSA-453276
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of PTEN stability and activity R-HSA-8948751
Hedgehog 'on' state R-HSA-5632684
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Independent DNA Damage Response R-HSA-69610
Interleukin-1 signaling R-HSA-9020702
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CLEC7A (Dectin-1) signaling R-HSA-5607764
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX2 expression and activity R-HSA-8939902
M Phase R-HSA-68886
Signaling by NOTCH R-HSA-157118
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of beta-catenin by the destruction complex R-HSA-195253
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G1/S Transition R-HSA-69206
Signaling by ROBO receptors R-HSA-376176
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transcriptional regulation by RUNX1 R-HSA-8878171
ABC-family proteins mediated transport R-HSA-382556
G1/S DNA Damage Checkpoints R-HSA-69615
Infectious disease R-HSA-5663205
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
ABC transporter disorders R-HSA-5619084
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 family signaling R-HSA-446652
Defective CFTR causes cystic fibrosis R-HSA-5678895
UCH proteinases R-HSA-5689603
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'off' state R-HSA-5610787
Activation of NF-kappaB in B cells R-HSA-1169091
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M Transition R-HSA-69275
PTEN Regulation R-HSA-6807070
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of RNA R-HSA-8953854
Degradation of GLI2 by the proteasome R-HSA-5610783
Apoptosis R-HSA-109581
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism R-HSA-1430728
Cellular response to hypoxia R-HSA-1234174
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
HIV Infection R-HSA-162906
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH R-HSA-157118
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PTEN Regulation R-HSA-6807070
Hh mutants are degraded by ERAD R-HSA-5362768
Separation of Sister Chromatids R-HSA-2467813
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'on' state R-HSA-5632684
Switching of origins to a post-replicative state R-HSA-69052
Synthesis of DNA R-HSA-69239
Regulation of RAS by GAPs R-HSA-5658442
Signaling by NOTCH4 R-HSA-9013694
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cyclin E associated events during G1/S transition R-HSA-69202
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants abrogate ligand secretion R-HSA-5387390
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle, Mitotic R-HSA-69278
Signaling by ROBO receptors R-HSA-376176
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
Interleukin-1 signaling R-HSA-9020702
Post-translational protein modification R-HSA-597592
Nervous system development R-HSA-9675108
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular responses to stimuli R-HSA-8953897
G2/M Checkpoints R-HSA-69481
Nuclear events mediated by NFE2L2 R-HSA-9759194
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle R-HSA-1640170
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX3 expression and activity R-HSA-8941858
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX3 R-HSA-8878159
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Defective CFTR causes cystic fibrosis R-HSA-5678895
Stabilization of p53 R-HSA-69541
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by Interleukins R-HSA-449147
ER-Phagosome pathway R-HSA-1236974
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog 'off' state R-HSA-5610787
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
S Phase R-HSA-69242
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Vpu mediated degradation of CD4 R-HSA-180534
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RAF/MAP kinase cascade R-HSA-5673001
TCF dependent signaling in response to WNT R-HSA-201681
Transport of small molecules R-HSA-382551
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Cytokine Signaling in Immune system R-HSA-1280215
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of RNA R-HSA-8953854
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular responses to stress R-HSA-2262752
DNA Replication R-HSA-69306
ABC transporter disorders R-HSA-5619084
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of polyamines R-HSA-351202
Degradation of beta-catenin by the destruction complex R-HSA-195253
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neutrophil degranulation R-HSA-6798695
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
Innate Immune System R-HSA-168249
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle Checkpoints R-HSA-69620
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ub-specific processing proteases R-HSA-5689880
KEAP1-NFE2L2 pathway R-HSA-9755511
Disorders of transmembrane transporters R-HSA-5619115
Vif-mediated degradation of APOBEC3G R-HSA-180585
Deubiquitination R-HSA-5688426
Hedgehog ligand biogenesis R-HSA-5358346
Orc1 removal from chromatin R-HSA-68949
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism R-HSA-1430728
Class I MHC mediated antigen processing & presentation R-HSA-983169
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular response to chemical stress R-HSA-9711123
Degradation of GLI2 by the proteasome R-HSA-5610783
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
ABC-family proteins mediated transport R-HSA-382556
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
M Phase R-HSA-68886
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of DVL R-HSA-4641258
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
TCR signaling R-HSA-202403
Programmed Cell Death R-HSA-5357801
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
Metabolism R-HSA-1430728
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Class I MHC mediated antigen processing & presentation R-HSA-983169
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
HIV Infection R-HSA-162906
Degradation of DVL R-HSA-4641258
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Hedgehog R-HSA-5358351
Immune System R-HSA-168256
Transcriptional regulation by RUNX1 R-HSA-8878171
ABC-family proteins mediated transport R-HSA-382556
Mitotic Anaphase R-HSA-68882
Cell Cycle R-HSA-1640170
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'on' state R-HSA-5632684
Cytokine Signaling in Immune system R-HSA-1280215
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ER-Phagosome pathway R-HSA-1236974
Apoptosis R-HSA-109581
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Switching of origins to a post-replicative state R-HSA-69052
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication Pre-Initiation R-HSA-69002
Neutrophil degranulation R-HSA-6798695
Transport of small molecules R-HSA-382551
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
M Phase R-HSA-68886
Assembly of the pre-replicative complex R-HSA-68867
G1/S Transition R-HSA-69206
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants are degraded by ERAD R-HSA-5362768
Deubiquitination R-HSA-5688426
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
Cyclin E associated events during G1/S transition R-HSA-69202
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ub-specific processing proteases R-HSA-5689880
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by Interleukins R-HSA-449147
Orc1 removal from chromatin R-HSA-68949
G2/M Transition R-HSA-69275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic G1 phase and G1/S transition R-HSA-453279
Intracellular signaling by second messengers R-HSA-9006925
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Separation of Sister Chromatids R-HSA-2467813
CLEC7A (Dectin-1) signaling R-HSA-5607764
PCP/CE pathway R-HSA-4086400
PTEN Regulation R-HSA-6807070
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication R-HSA-69306
G2/M Checkpoints R-HSA-69481
Cellular response to hypoxia R-HSA-1234174
Cell Cycle, Mitotic R-HSA-69278
Vif-mediated degradation of APOBEC3G R-HSA-180585
Disorders of transmembrane transporters R-HSA-5619115
Cellular response to chemical stress R-HSA-9711123
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of Apoptosis R-HSA-169911
p53-Independent DNA Damage Response R-HSA-69610
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of GLI2 by the proteasome R-HSA-5610783
Defective CFTR causes cystic fibrosis R-HSA-5678895
S Phase R-HSA-69242
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of GLI1 by the proteasome R-HSA-5610780
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of AXIN R-HSA-4641257
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by ROBO receptors R-HSA-376176
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RNA Polymerase II Transcription R-HSA-73857
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 signaling R-HSA-9020702
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RAS by GAPs R-HSA-5658442
Signaling by WNT R-HSA-195721
Post-translational protein modification R-HSA-597592
Disease R-HSA-1643685
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle Checkpoints R-HSA-69620
Negative regulation of NOTCH4 signaling R-HSA-9604323
Synthesis of DNA R-HSA-69239
Metabolism of RNA R-HSA-8953854
TCR signaling R-HSA-202403
UCH proteinases R-HSA-5689603
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX3 R-HSA-8878159
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
MAPK1/MAPK3 signaling R-HSA-5684996
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Gene expression (Transcription) R-HSA-74160
Cellular response to hypoxia R-HSA-1234174
Developmental Biology R-HSA-1266738
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of proteins R-HSA-392499
Antigen processing-Cross presentation R-HSA-1236975
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Neutrophil degranulation R-HSA-6798695
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Neddylation R-HSA-8951664
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S DNA Damage Checkpoints R-HSA-69615
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX2 R-HSA-8878166
Ub-specific processing proteases R-HSA-5689880
NIK-->noncanonical NF-kB signaling R-HSA-5676590
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Negative regulation of NOTCH4 signaling R-HSA-9604323
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
S Phase R-HSA-69242
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
ER-Phagosome pathway R-HSA-1236974
Mitotic G2-G2/M phases R-HSA-453274
MAPK6/MAPK4 signaling R-HSA-5687128
G2/M Checkpoints R-HSA-69481
Regulation of mitotic cell cycle R-HSA-453276
Degradation of GLI2 by the proteasome R-HSA-5610783
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
Cell Cycle R-HSA-1640170
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK1/MAPK3 signaling R-HSA-5684996
Transport of small molecules R-HSA-382551
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
Mitotic G1 phase and G1/S transition R-HSA-453279
ABC-family proteins mediated transport R-HSA-382556
Nuclear events mediated by NFE2L2 R-HSA-9759194
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX3 expression and activity R-HSA-8941858
Orc1 removal from chromatin R-HSA-68949
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Class I MHC mediated antigen processing & presentation R-HSA-983169
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
Axon guidance R-HSA-422475
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
UCH proteinases R-HSA-5689603
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin E associated events during G1/S transition R-HSA-69202
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Metabolism of RNA R-HSA-8953854
FCERI mediated NF-kB activation R-HSA-2871837
Nervous system development R-HSA-9675108
Asymmetric localization of PCP proteins R-HSA-4608870
HIV Infection R-HSA-162906
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Synthesis of DNA R-HSA-69239
Activation of NF-kappaB in B cells R-HSA-1169091
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Disorders of transmembrane transporters R-HSA-5619115
Post-translational protein modification R-HSA-597592
Cellular responses to stress R-HSA-2262752
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by WNT R-HSA-195721
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by NOTCH4 R-HSA-9013694
Metabolism R-HSA-1430728
Assembly of the pre-replicative complex R-HSA-68867
Hedgehog 'off' state R-HSA-5610787
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Stabilization of p53 R-HSA-69541
MAPK family signaling cascades R-HSA-5683057
Signaling by Hedgehog R-HSA-5358351
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hedgehog 'on' state R-HSA-5632684
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disease R-HSA-1643685
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Intracellular signaling by second messengers R-HSA-9006925
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Signaling by ROBO receptors R-HSA-376176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 family signaling R-HSA-446652
G1/S Transition R-HSA-69206
Generic Transcription Pathway R-HSA-212436
Metabolism of polyamines R-HSA-351202
Signaling by Interleukins R-HSA-449147
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
Deubiquitination R-HSA-5688426
Interleukin-1 signaling R-HSA-9020702
Separation of Sister Chromatids R-HSA-2467813
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of AXIN R-HSA-4641257
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle Checkpoints R-HSA-69620
Host Interactions of HIV factors R-HSA-162909
Innate Immune System R-HSA-168249
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Innate Immune System R-HSA-168249
Mitotic G1 phase and G1/S transition R-HSA-453279
Infectious disease R-HSA-5663205
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle, Mitotic R-HSA-69278
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Cellular response to chemical stress R-HSA-9711123
Switching of origins to a post-replicative state R-HSA-69052
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Neddylation R-HSA-8951664
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Dependent G1 DNA Damage Response R-HSA-69563
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transport of small molecules R-HSA-382551
Metabolism of polyamines R-HSA-351202
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'off' state R-HSA-5610787
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent DNA Damage Response R-HSA-69610
Disorders of transmembrane transporters R-HSA-5619115
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cell Cycle Checkpoints R-HSA-69620
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Disease R-HSA-1643685
G2/M Transition R-HSA-69275
G2/M Checkpoints R-HSA-69481
Antigen processing-Cross presentation R-HSA-1236975
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Adaptive Immune System R-HSA-1280218
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication R-HSA-69306
Immune System R-HSA-168256
Hedgehog 'on' state R-HSA-5632684
Metabolism R-HSA-1430728
Cellular responses to stress R-HSA-2262752
ABC transporter disorders R-HSA-5619084
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX3 R-HSA-8878159
Vpu mediated degradation of CD4 R-HSA-180534
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX1 R-HSA-8878171
UCH proteinases R-HSA-5689603
Signaling by Interleukins R-HSA-449147
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX2 R-HSA-8878166
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hh mutants are degraded by ERAD R-HSA-5362768
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK family signaling cascades R-HSA-5683057
Cell Cycle R-HSA-1640170
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MAPK1/MAPK3 signaling R-HSA-5684996
Separation of Sister Chromatids R-HSA-2467813
Interleukin-1 signaling R-HSA-9020702
Post-translational protein modification R-HSA-597592
HIV Infection R-HSA-162906
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Neutrophil degranulation R-HSA-6798695
Degradation of GLI1 by the proteasome R-HSA-5610780
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH4 R-HSA-9013694
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Synthesis of DNA R-HSA-69239
Metabolism of proteins R-HSA-392499
Degradation of DVL R-HSA-4641258
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by Hedgehog R-HSA-5358351
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Assembly of the pre-replicative complex R-HSA-68867
Programmed Cell Death R-HSA-5357801
Signal Transduction R-HSA-162582
DNA Replication Pre-Initiation R-HSA-69002
Signaling by NOTCH R-HSA-157118
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of GLI2 by the proteasome R-HSA-5610783
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Intracellular signaling by second messengers R-HSA-9006925
Class I MHC mediated antigen processing & presentation R-HSA-983169
Activation of NF-kappaB in B cells R-HSA-1169091
Ub-specific processing proteases R-HSA-5689880
RNA Polymerase II Transcription R-HSA-73857
Axon guidance R-HSA-422475
G1/S DNA Damage Checkpoints R-HSA-69615
PTEN Regulation R-HSA-6807070
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular responses to stimuli R-HSA-8953897
Negative regulation of NOTCH4 signaling R-HSA-9604323
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
M Phase R-HSA-68886
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mitotic cell cycle R-HSA-453276
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 family signaling R-HSA-446652
Downstream TCR signaling R-HSA-202424
ABC-family proteins mediated transport R-HSA-382556
Regulation of Apoptosis R-HSA-169911
Developmental Biology R-HSA-1266738
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
RAF/MAP kinase cascade R-HSA-5673001
G1/S Transition R-HSA-69206
Degradation of AXIN R-HSA-4641257
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by WNT R-HSA-195721
PCP/CE pathway R-HSA-4086400
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of PTEN stability and activity R-HSA-8948751
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RAS by GAPs R-HSA-5658442
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
Nervous system development R-HSA-9675108
Neddylation R-HSA-8951664
Degradation of DVL R-HSA-4641258
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signaling by Hedgehog R-HSA-5358351
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Disease R-HSA-1643685
Degradation of AXIN R-HSA-4641257
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1 DNA Damage Response R-HSA-69563
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of RNA R-HSA-8953854
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Interleukin-1 signaling R-HSA-9020702
Mitotic G1 phase and G1/S transition R-HSA-453279
Disorders of transmembrane transporters R-HSA-5619115
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Intracellular signaling by second messengers R-HSA-9006925
ABC-family proteins mediated transport R-HSA-382556
Mitotic Anaphase R-HSA-68882
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PTEN Regulation R-HSA-6807070
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Metabolism of polyamines R-HSA-351202
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
Signaling by WNT R-HSA-195721
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Vpu mediated degradation of CD4 R-HSA-180534
Innate Immune System R-HSA-168249
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Defective CFTR causes cystic fibrosis R-HSA-5678895
Axon guidance R-HSA-422475
Hh mutants are degraded by ERAD R-HSA-5362768
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
PCP/CE pathway R-HSA-4086400
Ub-specific processing proteases R-HSA-5689880
G1/S DNA Damage Checkpoints R-HSA-69615
Post-translational protein modification R-HSA-597592
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Assembly of the pre-replicative complex R-HSA-68867
G2/M Checkpoints R-HSA-69481
M Phase R-HSA-68886
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
C-type lectin receptors (CLRs) R-HSA-5621481
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of proteins R-HSA-392499
Adaptive Immune System R-HSA-1280218
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCF dependent signaling in response to WNT R-HSA-201681
Hh mutants abrogate ligand secretion R-HSA-5387390
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism R-HSA-1430728
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream TCR signaling R-HSA-202424
Cellular responses to stress R-HSA-2262752
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle Checkpoints R-HSA-69620
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vif-mediated degradation of APOBEC3G R-HSA-180585
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Asymmetric localization of PCP proteins R-HSA-4608870
Stabilization of p53 R-HSA-69541
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of Apoptosis R-HSA-169911
UCH proteinases R-HSA-5689603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC transporter disorders R-HSA-5619084
Generic Transcription Pathway R-HSA-212436
Apoptosis R-HSA-109581
Neutrophil degranulation R-HSA-6798695
Cellular responses to stimuli R-HSA-8953897
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
HIV Infection R-HSA-162906
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
DNA Replication Pre-Initiation R-HSA-69002
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH4 R-HSA-9013694
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RNA Polymerase II Transcription R-HSA-73857
Transport of small molecules R-HSA-382551
Activation of NF-kappaB in B cells R-HSA-1169091
Orc1 removal from chromatin R-HSA-68949
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by ROBO receptors R-HSA-376176
ER-Phagosome pathway R-HSA-1236974
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Signaling by NOTCH R-HSA-157118
Cellular response to chemical stress R-HSA-9711123
Signal Transduction R-HSA-162582
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog 'on' state R-HSA-5632684
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Switching of origins to a post-replicative state R-HSA-69052
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of amino acids and derivatives R-HSA-71291
Host Interactions of HIV factors R-HSA-162909
HIV Infection R-HSA-162906
PCP/CE pathway R-HSA-4086400
Separation of Sister Chromatids R-HSA-2467813
Neddylation R-HSA-8951664
Signaling by NOTCH4 R-HSA-9013694
Vpu mediated degradation of CD4 R-HSA-180534
RNA Polymerase II Transcription R-HSA-73857
Programmed Cell Death R-HSA-5357801
Regulation of expression of SLITs and ROBOs R-HSA-9010553
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Hedgehog R-HSA-5358351
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
UCH proteinases R-HSA-5689603
Orc1 removal from chromatin R-HSA-68949
Ub-specific processing proteases R-HSA-5689880
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent DNA Damage Response R-HSA-69610
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of AXIN R-HSA-4641257
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Regulation of Apoptosis R-HSA-169911
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Apoptosis R-HSA-109581
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX3 R-HSA-8878159
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of mitotic cell cycle R-HSA-453276
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of DVL R-HSA-4641258
ER-Phagosome pathway R-HSA-1236974
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Synthesis of DNA R-HSA-69239
DNA Replication R-HSA-69306
Regulation of RUNX3 expression and activity R-HSA-8941858
Beta-catenin independent WNT signaling R-HSA-3858494
Signal Transduction R-HSA-162582
Metabolism of polyamines R-HSA-351202
Neutrophil degranulation R-HSA-6798695
Asymmetric localization of PCP proteins R-HSA-4608870
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
Regulation of RAS by GAPs R-HSA-5658442
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH R-HSA-157118
Disorders of transmembrane transporters R-HSA-5619115
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular responses to stimuli R-HSA-8953897
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S DNA Damage Checkpoints R-HSA-69615
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular response to hypoxia R-HSA-1234174
Signaling by WNT R-HSA-195721
Assembly of the pre-replicative complex R-HSA-68867
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
p53-Dependent G1 DNA Damage Response R-HSA-69563
Host Interactions of HIV factors R-HSA-162909
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of NF-kappaB in B cells R-HSA-1169091
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism R-HSA-1430728
G1/S Transition R-HSA-69206
M Phase R-HSA-68886
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of beta-catenin by the destruction complex R-HSA-195253
Switching of origins to a post-replicative state R-HSA-69052
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Class I MHC mediated antigen processing & presentation R-HSA-983169
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX1 R-HSA-8878171
ABC transporter disorders R-HSA-5619084
Cellular responses to stress R-HSA-2262752
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle, Mitotic R-HSA-69278
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of GLI1 by the proteasome R-HSA-5610780
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic Metaphase and Anaphase R-HSA-2555396
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of amino acids and derivatives R-HSA-71291
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of proteins R-HSA-392499
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'on' state R-HSA-5632684
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
Axon guidance R-HSA-422475
G2/M Checkpoints R-HSA-69481
Signaling by Interleukins R-HSA-449147
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle R-HSA-1640170
S Phase R-HSA-69242
MAPK family signaling cascades R-HSA-5683057

Expression Atlas ENSG00000106588
NCBI gene (formerly Entrezgene) 5683
GeneCards 9531
HGNC Symbol HGNC:9531
MIM gene 176842
UniProtKB Gene Name P25787
WikiGene 5683
Gene: PIK3R3
Ensembl ID : ENSG00000117461
Description: phosphoinositide-3-kinase regulatory subunit 3
Gene Synonyms: P55
26 APIs:
276 Possible Orthologues:

Metabolism of lipids R-HSA-556833
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases R-HSA-194315
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Metabolism R-HSA-1430728
Phospholipid metabolism R-HSA-1483257
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
PI Metabolism R-HSA-1483255
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Axon guidance R-HSA-422475
Platelet activation, signaling and aggregation R-HSA-76002
Interleukin receptor SHC signaling R-HSA-912526
Developmental Biology R-HSA-1266738
PI3K/AKT Signaling in Cancer R-HSA-2219528
Synthesis of PIPs at the plasma membrane R-HSA-1660499
GPCR downstream signalling R-HSA-388396
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAC1 GTPase cycle R-HSA-9013149
PIP3 activates AKT signaling R-HSA-1257604
Signaling by SCF-KIT R-HSA-1433557
G alpha (q) signalling events R-HSA-416476
CD28 co-stimulation R-HSA-389356
Intracellular signaling by second messengers R-HSA-9006925
Interleukin-7 signaling R-HSA-1266695
ESR-mediated signaling R-HSA-8939211
Signaling by GPCR R-HSA-372790
Extra-nuclear estrogen signaling R-HSA-9009391
Immune System R-HSA-168256
Hemostasis R-HSA-109582
Interleukin-2 family signaling R-HSA-451927
GPVI-mediated activation cascade R-HSA-114604
Adaptive Immune System R-HSA-1280218
Negative regulation of the PI3K/AKT network R-HSA-199418
RAC2 GTPase cycle R-HSA-9013404
RHO GTPase cycle R-HSA-9012999
Disease R-HSA-1643685
RET signaling R-HSA-8853659
Costimulation by the CD28 family R-HSA-388841
Regulation of signaling by CBL R-HSA-912631
CD28 dependent PI3K/Akt signaling R-HSA-389357
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by KIT in disease R-HSA-9669938
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Interleukin-2 family signaling R-HSA-451927
Signaling by Rho GTPases R-HSA-194315
ESR-mediated signaling R-HSA-8939211
Developmental Biology R-HSA-1266738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
CD28 co-stimulation R-HSA-389356
Signaling by GPCR R-HSA-372790
Interleukin receptor SHC signaling R-HSA-912526
Metabolism R-HSA-1430728
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G alpha (q) signalling events R-HSA-416476
RAC2 GTPase cycle R-HSA-9013404
Signaling by Nuclear Receptors R-HSA-9006931
GPVI-mediated activation cascade R-HSA-114604
PI Metabolism R-HSA-1483255
Interleukin-7 signaling R-HSA-1266695
GPCR downstream signalling R-HSA-388396
Extra-nuclear estrogen signaling R-HSA-9009391
Nervous system development R-HSA-9675108
Costimulation by the CD28 family R-HSA-388841
Signaling by KIT in disease R-HSA-9669938
Axon guidance R-HSA-422475
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
RHO GTPase cycle R-HSA-9012999
CD28 dependent PI3K/Akt signaling R-HSA-389357
Immune System R-HSA-168256
RET signaling R-HSA-8853659
PI3K/AKT Signaling in Cancer R-HSA-2219528
Hemostasis R-HSA-109582
RAC1 GTPase cycle R-HSA-9013149
Regulation of signaling by CBL R-HSA-912631
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by SCF-KIT R-HSA-1433557
PIP3 activates AKT signaling R-HSA-1257604
Phospholipid metabolism R-HSA-1483257
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Disease R-HSA-1643685
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism of lipids R-HSA-556833
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Phospholipid metabolism R-HSA-1483257
Interleukin-7 signaling R-HSA-1266695
RAC1 GTPase cycle R-HSA-9013149
CD28 dependent PI3K/Akt signaling R-HSA-389357
Disease R-HSA-1643685
GPCR downstream signalling R-HSA-388396
ESR-mediated signaling R-HSA-8939211
Signaling by GPCR R-HSA-372790
PI Metabolism R-HSA-1483255
Costimulation by the CD28 family R-HSA-388841
Signaling by Nuclear Receptors R-HSA-9006931
Axon guidance R-HSA-422475
CD28 co-stimulation R-HSA-389356
Adaptive Immune System R-HSA-1280218
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Interleukins R-HSA-449147
GPVI-mediated activation cascade R-HSA-114604
G alpha (q) signalling events R-HSA-416476
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
Platelet activation, signaling and aggregation R-HSA-76002
Extra-nuclear estrogen signaling R-HSA-9009391
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases R-HSA-194315
Negative regulation of the PI3K/AKT network R-HSA-199418
RHO GTPase cycle R-HSA-9012999
Interleukin receptor SHC signaling R-HSA-912526
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by KIT in disease R-HSA-9669938
Signal Transduction R-HSA-162582
Metabolism of lipids R-HSA-556833
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Hemostasis R-HSA-109582
Regulation of signaling by CBL R-HSA-912631
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Interleukin-2 family signaling R-HSA-451927
RAC2 GTPase cycle R-HSA-9013404
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RET signaling R-HSA-8853659
Signaling by SCF-KIT R-HSA-1433557
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Negative regulation of the PI3K/AKT network R-HSA-199418
Hemostasis R-HSA-109582
CD28 co-stimulation R-HSA-389356
Interleukin receptor SHC signaling R-HSA-912526
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
GPCR downstream signalling R-HSA-388396
Costimulation by the CD28 family R-HSA-388841
Immune System R-HSA-168256
Signaling by Nuclear Receptors R-HSA-9006931
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by SCF-KIT R-HSA-1433557
Signaling by GPCR R-HSA-372790
RHO GTPase cycle R-HSA-9012999
Metabolism R-HSA-1430728
PI3K/AKT Signaling in Cancer R-HSA-2219528
RET signaling R-HSA-8853659
Extra-nuclear estrogen signaling R-HSA-9009391
Platelet activation, signaling and aggregation R-HSA-76002
PI Metabolism R-HSA-1483255
Developmental Biology R-HSA-1266738
Signaling by KIT in disease R-HSA-9669938
Adaptive Immune System R-HSA-1280218
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Phospholipid metabolism R-HSA-1483257
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Rho GTPases R-HSA-194315
Interleukin-2 family signaling R-HSA-451927
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
RAC2 GTPase cycle R-HSA-9013404
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Nervous system development R-HSA-9675108
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Interleukins R-HSA-449147
CD28 dependent PI3K/Akt signaling R-HSA-389357
Interleukin-7 signaling R-HSA-1266695
Axon guidance R-HSA-422475
GPVI-mediated activation cascade R-HSA-114604
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Metabolism of lipids R-HSA-556833
Regulation of signaling by CBL R-HSA-912631
ESR-mediated signaling R-HSA-8939211
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAC1 GTPase cycle R-HSA-9013149
PIP3 activates AKT signaling R-HSA-1257604
Phospholipid metabolism R-HSA-1483257
Signaling by Interleukins R-HSA-449147
ESR-mediated signaling R-HSA-8939211
GPVI-mediated activation cascade R-HSA-114604
Interleukin receptor SHC signaling R-HSA-912526
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Interleukin-2 family signaling R-HSA-451927
GPCR downstream signalling R-HSA-388396
Immune System R-HSA-168256
Signaling by SCF-KIT R-HSA-1433557
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Interleukin-7 signaling R-HSA-1266695
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Hemostasis R-HSA-109582
Negative regulation of the PI3K/AKT network R-HSA-199418
RHO GTPase cycle R-HSA-9012999
CD28 dependent PI3K/Akt signaling R-HSA-389357
Metabolism R-HSA-1430728
Costimulation by the CD28 family R-HSA-388841
Signaling by Rho GTPases R-HSA-194315
Platelet activation, signaling and aggregation R-HSA-76002
PI Metabolism R-HSA-1483255
Signaling by Nuclear Receptors R-HSA-9006931
Intracellular signaling by second messengers R-HSA-9006925
Adaptive Immune System R-HSA-1280218
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by GPCR R-HSA-372790
CD28 co-stimulation R-HSA-389356
G alpha (q) signalling events R-HSA-416476
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
RAC2 GTPase cycle R-HSA-9013404
Developmental Biology R-HSA-1266738
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Signaling by KIT in disease R-HSA-9669938
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RAC1 GTPase cycle R-HSA-9013149
Axon guidance R-HSA-422475
Metabolism of lipids R-HSA-556833
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
RET signaling R-HSA-8853659
PIP3 activates AKT signaling R-HSA-1257604
Regulation of signaling by CBL R-HSA-912631
Extra-nuclear estrogen signaling R-HSA-9009391
PI3K/AKT Signaling in Cancer R-HSA-2219528
Nervous system development R-HSA-9675108
GPCR downstream signalling R-HSA-388396
Extra-nuclear estrogen signaling R-HSA-9009391
Platelet activation, signaling and aggregation R-HSA-76002
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
CD28 dependent PI3K/Akt signaling R-HSA-389357
RHO GTPase cycle R-HSA-9012999
Hemostasis R-HSA-109582
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Metabolism of lipids R-HSA-556833
Disease R-HSA-1643685
RET signaling R-HSA-8853659
Phospholipid metabolism R-HSA-1483257
PI3K/AKT Signaling in Cancer R-HSA-2219528
GPVI-mediated activation cascade R-HSA-114604
PI Metabolism R-HSA-1483255
Adaptive Immune System R-HSA-1280218
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Nervous system development R-HSA-9675108
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAC2 GTPase cycle R-HSA-9013404
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of signaling by CBL R-HSA-912631
Interleukin-2 family signaling R-HSA-451927
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by GPCR R-HSA-372790
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Costimulation by the CD28 family R-HSA-388841
Immune System R-HSA-168256
CD28 co-stimulation R-HSA-389356
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
Negative regulation of the PI3K/AKT network R-HSA-199418
Interleukin receptor SHC signaling R-HSA-912526
Signaling by SCF-KIT R-HSA-1433557
Interleukin-7 signaling R-HSA-1266695
Signaling by Interleukins R-HSA-449147
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
Metabolism R-HSA-1430728
Signaling by KIT in disease R-HSA-9669938
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Rho GTPases R-HSA-194315
ESR-mediated signaling R-HSA-8939211
RAC1 GTPase cycle R-HSA-9013149
Interleukin receptor SHC signaling R-HSA-912526
Synthesis of PIPs at the plasma membrane R-HSA-1660499
RET signaling R-HSA-8853659
Hemostasis R-HSA-109582
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Metabolism of lipids R-HSA-556833
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RHO GTPase cycle R-HSA-9012999
G alpha (q) signalling events R-HSA-416476
Axon guidance R-HSA-422475
Immune System R-HSA-168256
RAC1 GTPase cycle R-HSA-9013149
Signaling by Interleukins R-HSA-449147
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by SCF-KIT R-HSA-1433557
ESR-mediated signaling R-HSA-8939211
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Costimulation by the CD28 family R-HSA-388841
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
CD28 co-stimulation R-HSA-389356
Intracellular signaling by second messengers R-HSA-9006925
Adaptive Immune System R-HSA-1280218
Phospholipid metabolism R-HSA-1483257
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by GPCR R-HSA-372790
Signaling by Rho GTPases R-HSA-194315
Extra-nuclear estrogen signaling R-HSA-9009391
GPCR downstream signalling R-HSA-388396
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Interleukin-2 family signaling R-HSA-451927
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
GPVI-mediated activation cascade R-HSA-114604
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Signaling by KIT in disease R-HSA-9669938
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
PI Metabolism R-HSA-1483255
CD28 dependent PI3K/Akt signaling R-HSA-389357
RAC2 GTPase cycle R-HSA-9013404
Regulation of signaling by CBL R-HSA-912631
Interleukin-7 signaling R-HSA-1266695
Platelet activation, signaling and aggregation R-HSA-76002
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by SCF-KIT R-HSA-1433557
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Immune System R-HSA-168256
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by KIT in disease R-HSA-9669938
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
Costimulation by the CD28 family R-HSA-388841
PI Metabolism R-HSA-1483255
Signaling by GPCR R-HSA-372790
Interleukin-2 family signaling R-HSA-451927
Hemostasis R-HSA-109582
RHO GTPase cycle R-HSA-9012999
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases R-HSA-194315
Extra-nuclear estrogen signaling R-HSA-9009391
Interleukin receptor SHC signaling R-HSA-912526
Regulation of signaling by CBL R-HSA-912631
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
Platelet activation, signaling and aggregation R-HSA-76002
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RAC2 GTPase cycle R-HSA-9013404
PI3K/AKT Signaling in Cancer R-HSA-2219528
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
CD28 co-stimulation R-HSA-389356
RET signaling R-HSA-8853659
G alpha (q) signalling events R-HSA-416476
Signaling by Interleukins R-HSA-449147
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PIP3 activates AKT signaling R-HSA-1257604
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAC1 GTPase cycle R-HSA-9013149
Nervous system development R-HSA-9675108
Phospholipid metabolism R-HSA-1483257
Interleukin-7 signaling R-HSA-1266695
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Developmental Biology R-HSA-1266738
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
GPVI-mediated activation cascade R-HSA-114604
ESR-mediated signaling R-HSA-8939211
Adaptive Immune System R-HSA-1280218
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
GPCR downstream signalling R-HSA-388396
Interleukin-2 family signaling R-HSA-451927
Metabolism of lipids R-HSA-556833
Signaling by KIT in disease R-HSA-9669938
ESR-mediated signaling R-HSA-8939211
Metabolism R-HSA-1430728
Signaling by GPCR R-HSA-372790
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases R-HSA-194315
G alpha (q) signalling events R-HSA-416476
Nervous system development R-HSA-9675108
Costimulation by the CD28 family R-HSA-388841
Phospholipid metabolism R-HSA-1483257
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RAC1 GTPase cycle R-HSA-9013149
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signal Transduction R-HSA-162582
Signaling by SCF-KIT R-HSA-1433557
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Hemostasis R-HSA-109582
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Intracellular signaling by second messengers R-HSA-9006925
GPCR downstream signalling R-HSA-388396
Interleukin receptor SHC signaling R-HSA-912526
Extra-nuclear estrogen signaling R-HSA-9009391
Developmental Biology R-HSA-1266738
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Nuclear Receptors R-HSA-9006931
Regulation of signaling by CBL R-HSA-912631
RAC2 GTPase cycle R-HSA-9013404
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Platelet activation, signaling and aggregation R-HSA-76002
PI Metabolism R-HSA-1483255
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
GPVI-mediated activation cascade R-HSA-114604
RHO GTPase cycle R-HSA-9012999
RET signaling R-HSA-8853659
CD28 co-stimulation R-HSA-389356
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PI3K/AKT Signaling in Cancer R-HSA-2219528
Axon guidance R-HSA-422475
Interleukin-7 signaling R-HSA-1266695
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Rho GTPases R-HSA-194315
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by SCF-KIT R-HSA-1433557
Intracellular signaling by second messengers R-HSA-9006925
RHO GTPase cycle R-HSA-9012999
Signaling by Interleukins R-HSA-449147
Interleukin-2 family signaling R-HSA-451927
Axon guidance R-HSA-422475
PI Metabolism R-HSA-1483255
Signaling by KIT in disease R-HSA-9669938
GPVI-mediated activation cascade R-HSA-114604
Negative regulation of the PI3K/AKT network R-HSA-199418
RAC2 GTPase cycle R-HSA-9013404
G alpha (q) signalling events R-HSA-416476
Immune System R-HSA-168256
Signaling by GPCR R-HSA-372790
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Costimulation by the CD28 family R-HSA-388841
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Nuclear Receptors R-HSA-9006931
Interleukin-7 signaling R-HSA-1266695
Hemostasis R-HSA-109582
ESR-mediated signaling R-HSA-8939211
Adaptive Immune System R-HSA-1280218
GPCR downstream signalling R-HSA-388396
CD28 dependent PI3K/Akt signaling R-HSA-389357
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Cytokine Signaling in Immune system R-HSA-1280215
Developmental Biology R-HSA-1266738
Metabolism R-HSA-1430728
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Extra-nuclear estrogen signaling R-HSA-9009391
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
RET signaling R-HSA-8853659
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Regulation of signaling by CBL R-HSA-912631
PIP3 activates AKT signaling R-HSA-1257604
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism of lipids R-HSA-556833
RAC1 GTPase cycle R-HSA-9013149
Interleukin receptor SHC signaling R-HSA-912526
CD28 co-stimulation R-HSA-389356
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Phospholipid metabolism R-HSA-1483257

Expression Atlas ENSG00000117461
NCBI gene (formerly Entrezgene) 8503
GeneCards 8981
HGNC Symbol HGNC:8981
MIM gene 606076
UniProtKB Gene Name Q92569
WikiGene 8503
Gene: PSMC3
Ensembl ID : ENSG00000165916
Description: proteasome 26S subunit, ATPase 3
Gene Synonyms: RPT5,TBP-1,TBP1
5 APIs:
218 Possible Orthologues:

Mitotic Anaphase R-HSA-68882
Apoptosis R-HSA-109581
Infectious disease R-HSA-5663205
G2/M Checkpoints R-HSA-69481
Hh mutants are degraded by ERAD R-HSA-5362768
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX2 R-HSA-8878166
Orc1 removal from chromatin R-HSA-68949
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Independent DNA Damage Response R-HSA-69610
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Innate Immune System R-HSA-168249
Negative regulation of NOTCH4 signaling R-HSA-9604323
S Phase R-HSA-69242
Cell Cycle, Mitotic R-HSA-69278
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic G2-G2/M phases R-HSA-453274
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog 'off' state R-HSA-5610787
p53-Dependent G1 DNA Damage Response R-HSA-69563
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
UCH proteinases R-HSA-5689603
Neutrophil degranulation R-HSA-6798695
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 signaling R-HSA-9020702
ABC transporter disorders R-HSA-5619084
Regulation of RAS by GAPs R-HSA-5658442
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Developmental Biology R-HSA-1266738
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of GLI1 by the proteasome R-HSA-5610780
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism R-HSA-1430728
Downstream TCR signaling R-HSA-202424
G1/S DNA Damage Checkpoints R-HSA-69615
FCERI mediated NF-kB activation R-HSA-2871837
G1/S Transition R-HSA-69206
Separation of Sister Chromatids R-HSA-2467813
MAPK6/MAPK4 signaling R-HSA-5687128
Post-translational protein modification R-HSA-597592
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of RNA R-HSA-8953854
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of AXIN R-HSA-4641257
Cellular responses to stimuli R-HSA-8953897
PTEN Regulation R-HSA-6807070
Disorders of transmembrane transporters R-HSA-5619115
M Phase R-HSA-68886
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Vpu mediated degradation of CD4 R-HSA-180534
Cellular response to hypoxia R-HSA-1234174
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PCP/CE pathway R-HSA-4086400
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
Axon guidance R-HSA-422475
Degradation of GLI2 by the proteasome R-HSA-5610783
Mitotic G1 phase and G1/S transition R-HSA-453279
HIV Infection R-HSA-162906
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of Apoptosis R-HSA-169911
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PIP3 activates AKT signaling R-HSA-1257604
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of NF-kappaB in B cells R-HSA-1169091
Hh mutants abrogate ligand secretion R-HSA-5387390
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by ROBO receptors R-HSA-376176
Cyclin E associated events during G1/S transition R-HSA-69202
Adaptive Immune System R-HSA-1280218
Hedgehog 'on' state R-HSA-5632684
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
KEAP1-NFE2L2 pathway R-HSA-9755511
Nuclear events mediated by NFE2L2 R-HSA-9759194
RAF/MAP kinase cascade R-HSA-5673001
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Switching of origins to a post-replicative state R-HSA-69052
Assembly of the pre-replicative complex R-HSA-68867
Signaling by Hedgehog R-HSA-5358351
DNA Replication R-HSA-69306
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Synthesis of DNA R-HSA-69239
Immune System R-HSA-168256
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Transition R-HSA-69275
ABC-family proteins mediated transport R-HSA-382556
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nervous system development R-HSA-9675108
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
DNA Replication Pre-Initiation R-HSA-69002
Transport of small molecules R-HSA-382551
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX1 R-HSA-8878171
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stimuli R-HSA-8953897
Signaling by ROBO receptors R-HSA-376176
Post-translational protein modification R-HSA-597592
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH4 R-HSA-9013694
DNA Replication R-HSA-69306
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Regulation of Apoptosis R-HSA-169911
RNA Polymerase II Transcription R-HSA-73857
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of DVL R-HSA-4641258
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G2-G2/M phases R-HSA-453274
Transcriptional regulation by RUNX1 R-HSA-8878171
UCH proteinases R-HSA-5689603
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX2 expression and activity R-HSA-8939902
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Axon guidance R-HSA-422475
G1/S DNA Damage Checkpoints R-HSA-69615
Neutrophil degranulation R-HSA-6798695
Disorders of transmembrane transporters R-HSA-5619115
TCR signaling R-HSA-202403
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
ABC transporter disorders R-HSA-5619084
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
PCP/CE pathway R-HSA-4086400
Switching of origins to a post-replicative state R-HSA-69052
Deubiquitination R-HSA-5688426
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Beta-catenin independent WNT signaling R-HSA-3858494
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transport of small molecules R-HSA-382551
Neddylation R-HSA-8951664
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
ABC-family proteins mediated transport R-HSA-382556
Downstream TCR signaling R-HSA-202424
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants are degraded by ERAD R-HSA-5362768
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RAF/MAP kinase cascade R-HSA-5673001
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stress R-HSA-2262752
Interleukin-1 signaling R-HSA-9020702
MAPK6/MAPK4 signaling R-HSA-5687128
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of polyamines R-HSA-351202
Apoptosis R-HSA-109581
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Immune System R-HSA-168256
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
MAPK family signaling cascades R-HSA-5683057
Disease R-HSA-1643685
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Mitotic Anaphase R-HSA-68882
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 family signaling R-HSA-446652
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH R-HSA-157118
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
M Phase R-HSA-68886
Regulation of PTEN stability and activity R-HSA-8948751
Ub-specific processing proteases R-HSA-5689880
Antigen processing-Cross presentation R-HSA-1236975
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
TCF dependent signaling in response to WNT R-HSA-201681
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of RNA R-HSA-8953854
Metabolism R-HSA-1430728
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by WNT R-HSA-195721
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'off' state R-HSA-5610787
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Class I MHC mediated antigen processing & presentation R-HSA-983169
ER-Phagosome pathway R-HSA-1236974
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
Stabilization of p53 R-HSA-69541
p53-Independent DNA Damage Response R-HSA-69610
Synthesis of DNA R-HSA-69239
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle, Mitotic R-HSA-69278
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of AXIN R-HSA-4641257
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Hedgehog R-HSA-5358351
Degradation of beta-catenin by the destruction complex R-HSA-195253
Generic Transcription Pathway R-HSA-212436
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
HIV Infection R-HSA-162906
Programmed Cell Death R-HSA-5357801
Negative regulation of NOTCH4 signaling R-HSA-9604323
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX3 R-HSA-8878159
Gene expression (Transcription) R-HSA-74160
Hh mutants abrogate ligand secretion R-HSA-5387390
Separation of Sister Chromatids R-HSA-2467813
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog 'on' state R-HSA-5632684
ER-Phagosome pathway R-HSA-1236974
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Generic Transcription Pathway R-HSA-212436
Degradation of GLI1 by the proteasome R-HSA-5610780
Mitotic Anaphase R-HSA-68882
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by Hedgehog R-HSA-5358351
Synthesis of DNA R-HSA-69239
RAF/MAP kinase cascade R-HSA-5673001
Disorders of transmembrane transporters R-HSA-5619115
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Developmental Biology R-HSA-1266738
Degradation of beta-catenin by the destruction complex R-HSA-195253
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PIP3 activates AKT signaling R-HSA-1257604
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transcriptional regulation by RUNX1 R-HSA-8878171
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular response to chemical stress R-HSA-9711123
Axon guidance R-HSA-422475
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Neddylation R-HSA-8951664
Mitotic G2-G2/M phases R-HSA-453274
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Infectious disease R-HSA-5663205
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Gene expression (Transcription) R-HSA-74160
Downstream TCR signaling R-HSA-202424
Class I MHC mediated antigen processing & presentation R-HSA-983169
Host Interactions of HIV factors R-HSA-162909
Intracellular signaling by second messengers R-HSA-9006925
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
PCP/CE pathway R-HSA-4086400
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular response to hypoxia R-HSA-1234174
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of Apoptosis R-HSA-169911
Metabolism of proteins R-HSA-392499
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism R-HSA-1430728
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S Transition R-HSA-69206
Signaling by NOTCH4 R-HSA-9013694
ABC transporter disorders R-HSA-5619084
Beta-catenin independent WNT signaling R-HSA-3858494
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RAS by GAPs R-HSA-5658442
Activation of NF-kappaB in B cells R-HSA-1169091
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
Assembly of the pre-replicative complex R-HSA-68867
Immune System R-HSA-168256
Transcriptional regulation by RUNX3 R-HSA-8878159
Hh mutants abrogate ligand secretion R-HSA-5387390
M Phase R-HSA-68886
Signaling by WNT R-HSA-195721
Deubiquitination R-HSA-5688426
Cellular responses to stimuli R-HSA-8953897
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
HIV Infection R-HSA-162906
Adaptive Immune System R-HSA-1280218
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
Hh mutants are degraded by ERAD R-HSA-5362768
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Nervous system development R-HSA-9675108
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of polyamines R-HSA-351202
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
Cytokine Signaling in Immune system R-HSA-1280215
UCH proteinases R-HSA-5689603
TCR signaling R-HSA-202403
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'on' state R-HSA-5632684
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of RUNX2 expression and activity R-HSA-8939902
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Vpu mediated degradation of CD4 R-HSA-180534
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Signaling by ROBO receptors R-HSA-376176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Interleukins R-HSA-449147
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle R-HSA-1640170
DNA Replication R-HSA-69306
Regulation of PTEN stability and activity R-HSA-8948751
MAPK1/MAPK3 signaling R-HSA-5684996
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Degradation of DVL R-HSA-4641258
Ub-specific processing proteases R-HSA-5689880
Hedgehog 'off' state R-HSA-5610787
Innate Immune System R-HSA-168249
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Neutrophil degranulation R-HSA-6798695
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK family signaling cascades R-HSA-5683057
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
G1/S DNA Damage Checkpoints R-HSA-69615
Disease R-HSA-1643685
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Cell Cycle Checkpoints R-HSA-69620
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Asymmetric localization of PCP proteins R-HSA-4608870
RNA Polymerase II Transcription R-HSA-73857
Orc1 removal from chromatin R-HSA-68949
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PTEN Regulation R-HSA-6807070
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of AXIN R-HSA-4641257
MAPK family signaling cascades R-HSA-5683057
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'off' state R-HSA-5610787
ABC-family proteins mediated transport R-HSA-382556
Signaling by NOTCH4 R-HSA-9013694
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hedgehog ligand biogenesis R-HSA-5358346
Disorders of transmembrane transporters R-HSA-5619115
Transcriptional regulation by RUNX1 R-HSA-8878171
Downstream TCR signaling R-HSA-202424
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Interleukin-1 signaling R-HSA-9020702
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Assembly of the pre-replicative complex R-HSA-68867
Intracellular signaling by second messengers R-HSA-9006925
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Hedgehog R-HSA-5358351
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX3 R-HSA-8878159
Developmental Biology R-HSA-1266738
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle Checkpoints R-HSA-69620
Cellular response to chemical stress R-HSA-9711123
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mitotic cell cycle R-HSA-453276
G1/S Transition R-HSA-69206
MAPK1/MAPK3 signaling R-HSA-5684996
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Neutrophil degranulation R-HSA-6798695
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
G2/M Transition R-HSA-69275
Hh mutants are degraded by ERAD R-HSA-5362768
Post-translational protein modification R-HSA-597592
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
C-type lectin receptors (CLRs) R-HSA-5621481
FCERI mediated NF-kB activation R-HSA-2871837
Synthesis of DNA R-HSA-69239
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Dependent G1 DNA Damage Response R-HSA-69563
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hh mutants abrogate ligand secretion R-HSA-5387390
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'on' state R-HSA-5632684
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
Interleukin-1 family signaling R-HSA-446652
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transport of small molecules R-HSA-382551
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of AXIN R-HSA-4641257
Cellular response to hypoxia R-HSA-1234174
p53-Independent DNA Damage Response R-HSA-69610
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Gene expression (Transcription) R-HSA-74160
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
Host Interactions of HIV factors R-HSA-162909
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of NF-kappaB in B cells R-HSA-1169091
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Switching of origins to a post-replicative state R-HSA-69052
Programmed Cell Death R-HSA-5357801
Metabolism of RNA R-HSA-8953854
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Signaling by the B Cell Receptor (BCR) R-HSA-983705
UCH proteinases R-HSA-5689603
Cell Cycle R-HSA-1640170
Cellular responses to stimuli R-HSA-8953897
Regulation of Apoptosis R-HSA-169911
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of RUNX3 expression and activity R-HSA-8941858
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Defective CFTR causes cystic fibrosis R-HSA-5678895
Orc1 removal from chromatin R-HSA-68949
Class I MHC mediated antigen processing & presentation R-HSA-983169
Stabilization of p53 R-HSA-69541
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of DVL R-HSA-4641258
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of polyamines R-HSA-351202
Apoptosis R-HSA-109581
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transcriptional regulation by RUNX2 R-HSA-8878166
ABC transporter disorders R-HSA-5619084
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Adaptive Immune System R-HSA-1280218
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI2 by the proteasome R-HSA-5610783
Cellular responses to stress R-HSA-2262752
HIV Infection R-HSA-162906
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G2/M Checkpoints R-HSA-69481
Signaling by WNT R-HSA-195721
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
Separation of Sister Chromatids R-HSA-2467813
Antigen processing-Cross presentation R-HSA-1236975
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication Pre-Initiation R-HSA-69002
PCP/CE pathway R-HSA-4086400
Nuclear events mediated by NFE2L2 R-HSA-9759194
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of polyamines R-HSA-351202
Intracellular signaling by second messengers R-HSA-9006925
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of AXIN R-HSA-4641257
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Neutrophil degranulation R-HSA-6798695
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
Generic Transcription Pathway R-HSA-212436
ER-Phagosome pathway R-HSA-1236974
Disorders of transmembrane transporters R-HSA-5619115
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Gene expression (Transcription) R-HSA-74160
Degradation of beta-catenin by the destruction complex R-HSA-195253
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transport of small molecules R-HSA-382551
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism of amino acids and derivatives R-HSA-71291
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RAS by GAPs R-HSA-5658442
Signaling by ROBO receptors R-HSA-376176
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by Interleukins R-HSA-449147
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Signaling by WNT R-HSA-195721
RNA Polymerase II Transcription R-HSA-73857
Programmed Cell Death R-HSA-5357801
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signal Transduction R-HSA-162582
Switching of origins to a post-replicative state R-HSA-69052
TCF dependent signaling in response to WNT R-HSA-201681
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FCERI mediated NF-kB activation R-HSA-2871837
TCR signaling R-HSA-202403
G2/M Checkpoints R-HSA-69481
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
S Phase R-HSA-69242
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'on' state R-HSA-5632684
PCP/CE pathway R-HSA-4086400
Negative regulation of NOTCH4 signaling R-HSA-9604323
HIV Infection R-HSA-162906
DNA Replication R-HSA-69306
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle, Mitotic R-HSA-69278
Signaling by Hedgehog R-HSA-5358351
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RUNX3 expression and activity R-HSA-8941858
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
M Phase R-HSA-68886
Adaptive Immune System R-HSA-1280218
Cell Cycle R-HSA-1640170
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI2 by the proteasome R-HSA-5610783
Infectious disease R-HSA-5663205
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
Assembly of the pre-replicative complex R-HSA-68867
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transcriptional regulation by RUNX3 R-HSA-8878159
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC transporter disorders R-HSA-5619084
Interleukin-1 family signaling R-HSA-446652
Mitotic G2-G2/M phases R-HSA-453274
Activation of NF-kappaB in B cells R-HSA-1169091
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Mitotic Anaphase R-HSA-68882
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism R-HSA-1430728
Signaling by NOTCH R-HSA-157118
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI1 by the proteasome R-HSA-5610780
Degradation of DVL R-HSA-4641258
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog ligand biogenesis R-HSA-5358346
Developmental Biology R-HSA-1266738
p53-Independent DNA Damage Response R-HSA-69610
G2/M Transition R-HSA-69275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Post-translational protein modification R-HSA-597592
MAPK1/MAPK3 signaling R-HSA-5684996
Axon guidance R-HSA-422475
Regulation of mitotic cell cycle R-HSA-453276
Vpu mediated degradation of CD4 R-HSA-180534
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX1 R-HSA-8878171
Stabilization of p53 R-HSA-69541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cell Cycle Checkpoints R-HSA-69620
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to hypoxia R-HSA-1234174
G1/S Transition R-HSA-69206
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Immune System R-HSA-168256
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism of RNA R-HSA-8953854
Hh mutants abrogate ligand secretion R-HSA-5387390
Nervous system development R-HSA-9675108
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK family signaling cascades R-HSA-5683057
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
PTEN Regulation R-HSA-6807070
Innate Immune System R-HSA-168249
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of proteins R-HSA-392499
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of Apoptosis R-HSA-169911
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G1/S DNA Damage Checkpoints R-HSA-69615
C-type lectin receptors (CLRs) R-HSA-5621481
DNA Replication Pre-Initiation R-HSA-69002
Cyclin E associated events during G1/S transition R-HSA-69202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
Disease R-HSA-1643685
Hedgehog 'off' state R-HSA-5610787
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cytokine Signaling in Immune system R-HSA-1280215
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
HIV Infection R-HSA-162906
DNA Replication R-HSA-69306
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by ROBO receptors R-HSA-376176
Apoptosis R-HSA-109581
Ub-specific processing proteases R-HSA-5689880
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of RNA R-HSA-8953854
Hedgehog 'on' state R-HSA-5632684
M Phase R-HSA-68886
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic Anaphase R-HSA-68882
Cellular response to chemical stress R-HSA-9711123
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Transition R-HSA-69275
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by NOTCH R-HSA-157118
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G2-G2/M phases R-HSA-453274
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing-Cross presentation R-HSA-1236975
Downstream TCR signaling R-HSA-202424
RAF/MAP kinase cascade R-HSA-5673001
Programmed Cell Death R-HSA-5357801
Stabilization of p53 R-HSA-69541
Cell Cycle Checkpoints R-HSA-69620
Gene expression (Transcription) R-HSA-74160
Separation of Sister Chromatids R-HSA-2467813
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ER-Phagosome pathway R-HSA-1236974
Asymmetric localization of PCP proteins R-HSA-4608870
Axon guidance R-HSA-422475
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX3 R-HSA-8878159
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle, Mitotic R-HSA-69278
Regulation of mitotic cell cycle R-HSA-453276
UCH proteinases R-HSA-5689603
TCR signaling R-HSA-202403
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
ABC-family proteins mediated transport R-HSA-382556
Signaling by Hedgehog R-HSA-5358351
Transport of small molecules R-HSA-382551
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX2 R-HSA-8878166
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Degradation of AXIN R-HSA-4641257
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Neutrophil degranulation R-HSA-6798695
Infectious disease R-HSA-5663205
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Independent DNA Damage Response R-HSA-69610
Orc1 removal from chromatin R-HSA-68949
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of RAS by GAPs R-HSA-5658442
Signal Transduction R-HSA-162582
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'off' state R-HSA-5610787
MAPK1/MAPK3 signaling R-HSA-5684996
Generic Transcription Pathway R-HSA-212436
ABC transporter disorders R-HSA-5619084
Post-translational protein modification R-HSA-597592
Regulation of PTEN stability and activity R-HSA-8948751
MAPK family signaling cascades R-HSA-5683057
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of Apoptosis R-HSA-169911
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of polyamines R-HSA-351202
Signaling by Interleukins R-HSA-449147
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vif-mediated degradation of APOBEC3G R-HSA-180585
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI2 by the proteasome R-HSA-5610783
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH4 R-HSA-9013694
Innate Immune System R-HSA-168249
G1/S Transition R-HSA-69206
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants abrogate ligand secretion R-HSA-5387390
Nervous system development R-HSA-9675108
Degradation of DVL R-HSA-4641258
PTEN Regulation R-HSA-6807070
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
FCERI mediated NF-kB activation R-HSA-2871837
Cellular responses to stress R-HSA-2262752
Hedgehog ligand biogenesis R-HSA-5358346
CLEC7A (Dectin-1) signaling R-HSA-5607764
Immune System R-HSA-168256
Regulation of RUNX2 expression and activity R-HSA-8939902
Developmental Biology R-HSA-1266738
Deubiquitination R-HSA-5688426
Interleukin-1 signaling R-HSA-9020702
Synthesis of DNA R-HSA-69239
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
p53-Dependent G1 DNA Damage Response R-HSA-69563
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Assembly of the pre-replicative complex R-HSA-68867
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of Apoptosis R-HSA-169911
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Intracellular signaling by second messengers R-HSA-9006925
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of AXIN R-HSA-4641257
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of proteins R-HSA-392499
ABC-family proteins mediated transport R-HSA-382556
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
Generic Transcription Pathway R-HSA-212436
Cyclin E associated events during G1/S transition R-HSA-69202
HIV Infection R-HSA-162906
Cellular response to hypoxia R-HSA-1234174
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX2 R-HSA-8878166
Disorders of transmembrane transporters R-HSA-5619115
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Post-translational protein modification R-HSA-597592
Degradation of DVL R-HSA-4641258
Separation of Sister Chromatids R-HSA-2467813
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G1/S DNA Damage Checkpoints R-HSA-69615
UCH proteinases R-HSA-5689603
Mitotic Anaphase R-HSA-68882
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Neutrophil degranulation R-HSA-6798695
RNA Polymerase II Transcription R-HSA-73857
G1/S Transition R-HSA-69206
Regulation of RUNX2 expression and activity R-HSA-8939902
DNA Replication Pre-Initiation R-HSA-69002
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Nervous system development R-HSA-9675108
Transport of small molecules R-HSA-382551
Developmental Biology R-HSA-1266738
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
Orc1 removal from chromatin R-HSA-68949
Cell Cycle Checkpoints R-HSA-69620
S Phase R-HSA-69242
Hh mutants abrogate ligand secretion R-HSA-5387390
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX3 expression and activity R-HSA-8941858
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by ROBO receptors R-HSA-376176
Stabilization of p53 R-HSA-69541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
Degradation of beta-catenin by the destruction complex R-HSA-195253
M Phase R-HSA-68886
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream TCR signaling R-HSA-202424
Antigen processing-Cross presentation R-HSA-1236975
Hh mutants are degraded by ERAD R-HSA-5362768
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PIP3 activates AKT signaling R-HSA-1257604
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK1/MAPK3 signaling R-HSA-5684996
ABC transporter disorders R-HSA-5619084
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mitotic cell cycle R-HSA-453276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
CLEC7A (Dectin-1) signaling R-HSA-5607764
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
Transcriptional regulation by RUNX3 R-HSA-8878159
Hedgehog 'off' state R-HSA-5610787
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH4 R-HSA-9013694
Hedgehog 'on' state R-HSA-5632684
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
Neddylation R-HSA-8951664
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to chemical stress R-HSA-9711123
Metabolism of RNA R-HSA-8953854
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
Gene expression (Transcription) R-HSA-74160
Metabolism of polyamines R-HSA-351202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Hedgehog R-HSA-5358351
Cell Cycle, Mitotic R-HSA-69278
ER-Phagosome pathway R-HSA-1236974
Host Interactions of HIV factors R-HSA-162909
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RAS by GAPs R-HSA-5658442
Cytokine Signaling in Immune system R-HSA-1280215
Deubiquitination R-HSA-5688426
PTEN Regulation R-HSA-6807070
Signaling by NOTCH R-HSA-157118
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by Interleukins R-HSA-449147
Degradation of GLI1 by the proteasome R-HSA-5610780
TCR signaling R-HSA-202403
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Innate Immune System R-HSA-168249
Beta-catenin independent WNT signaling R-HSA-3858494
Interleukin-1 signaling R-HSA-9020702
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Ub-specific processing proteases R-HSA-5689880
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle R-HSA-1640170
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'on' state R-HSA-5632684
Metabolism of RNA R-HSA-8953854
G2/M Checkpoints R-HSA-69481
ABC transporter disorders R-HSA-5619084
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RUNX2 expression and activity R-HSA-8939902
Assembly of the pre-replicative complex R-HSA-68867
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MAPK1/MAPK3 signaling R-HSA-5684996
Deubiquitination R-HSA-5688426
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX3 R-HSA-8878159
Developmental Biology R-HSA-1266738
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic Anaphase R-HSA-68882
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Beta-catenin independent WNT signaling R-HSA-3858494
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of GLI2 by the proteasome R-HSA-5610783
Disorders of transmembrane transporters R-HSA-5619115
Neutrophil degranulation R-HSA-6798695
Cell Cycle Checkpoints R-HSA-69620
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Apoptosis R-HSA-109581
Asymmetric localization of PCP proteins R-HSA-4608870
Axon guidance R-HSA-422475
Orc1 removal from chromatin R-HSA-68949
Cell Cycle, Mitotic R-HSA-69278
Hh mutants abrogate ligand secretion R-HSA-5387390
Nuclear events mediated by NFE2L2 R-HSA-9759194
Immune System R-HSA-168256
Regulation of Apoptosis R-HSA-169911
Disease R-HSA-1643685
Cellular response to hypoxia R-HSA-1234174
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cytokine Signaling in Immune system R-HSA-1280215
TCR signaling R-HSA-202403
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ER-Phagosome pathway R-HSA-1236974
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
FCERI mediated NF-kB activation R-HSA-2871837
Generic Transcription Pathway R-HSA-212436
p53-Independent DNA Damage Response R-HSA-69610
Degradation of DVL R-HSA-4641258
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog 'off' state R-HSA-5610787
Signaling by ROBO receptors R-HSA-376176
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stress R-HSA-2262752
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S DNA Damage Checkpoints R-HSA-69615
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
HIV Infection R-HSA-162906
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Nervous system development R-HSA-9675108
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Switching of origins to a post-replicative state R-HSA-69052
Degradation of AXIN R-HSA-4641257
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mitotic cell cycle R-HSA-453276
Signaling by NOTCH R-HSA-157118
Stabilization of p53 R-HSA-69541
Ub-specific processing proteases R-HSA-5689880
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
C-type lectin receptors (CLRs) R-HSA-5621481
Downstream TCR signaling R-HSA-202424
Metabolism of polyamines R-HSA-351202
Cyclin E associated events during G1/S transition R-HSA-69202
RAF/MAP kinase cascade R-HSA-5673001
S Phase R-HSA-69242
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by WNT R-HSA-195721
Signaling by NOTCH4 R-HSA-9013694
Synthesis of DNA R-HSA-69239
Class I MHC mediated antigen processing & presentation R-HSA-983169
Post-translational protein modification R-HSA-597592
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog ligand biogenesis R-HSA-5358346
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hh mutants are degraded by ERAD R-HSA-5362768
Gene expression (Transcription) R-HSA-74160
Regulation of PTEN stability and activity R-HSA-8948751
M Phase R-HSA-68886
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
UCH proteinases R-HSA-5689603
Interleukin-1 family signaling R-HSA-446652
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular responses to stimuli R-HSA-8953897
Regulation of RAS by GAPs R-HSA-5658442
G1/S Transition R-HSA-69206
PCP/CE pathway R-HSA-4086400
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cell Cycle R-HSA-1640170
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G2/M Transition R-HSA-69275
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1 DNA Damage Response R-HSA-69563
Infectious disease R-HSA-5663205
Antigen processing-Cross presentation R-HSA-1236975
Signal Transduction R-HSA-162582
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transport of small molecules R-HSA-382551
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RUNX3 expression and activity R-HSA-8941858
G2/M Transition R-HSA-69275
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
Interleukin-1 signaling R-HSA-9020702
Regulation of RUNX2 expression and activity R-HSA-8939902
TCR signaling R-HSA-202403
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of GLI2 by the proteasome R-HSA-5610783
Infectious disease R-HSA-5663205
Signaling by ROBO receptors R-HSA-376176
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cytokine Signaling in Immune system R-HSA-1280215
Orc1 removal from chromatin R-HSA-68949
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PTEN Regulation R-HSA-6807070
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Developmental Biology R-HSA-1266738
G2/M Checkpoints R-HSA-69481
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
G1/S Transition R-HSA-69206
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog ligand biogenesis R-HSA-5358346
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Disease R-HSA-1643685
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH R-HSA-157118
UCH proteinases R-HSA-5689603
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing-Cross presentation R-HSA-1236975
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cell Cycle R-HSA-1640170
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
RAF/MAP kinase cascade R-HSA-5673001
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ABC-family proteins mediated transport R-HSA-382556
M Phase R-HSA-68886
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Generic Transcription Pathway R-HSA-212436
Synthesis of DNA R-HSA-69239
Cell Cycle, Mitotic R-HSA-69278
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signal Transduction R-HSA-162582
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of RNA R-HSA-8953854
PIP3 activates AKT signaling R-HSA-1257604
DNA Replication R-HSA-69306
Assembly of the pre-replicative complex R-HSA-68867
Regulation of Apoptosis R-HSA-169911
Disorders of transmembrane transporters R-HSA-5619115
Programmed Cell Death R-HSA-5357801
CLEC7A (Dectin-1) signaling R-HSA-5607764
Nuclear events mediated by NFE2L2 R-HSA-9759194
Stabilization of p53 R-HSA-69541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stimuli R-HSA-8953897
Cellular response to chemical stress R-HSA-9711123
Innate Immune System R-HSA-168249
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Downstream TCR signaling R-HSA-202424
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hedgehog 'off' state R-HSA-5610787
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Asymmetric localization of PCP proteins R-HSA-4608870
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Independent DNA Damage Response R-HSA-69610
Transcriptional regulation by RUNX3 R-HSA-8878159
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HIV Infection R-HSA-162906
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Class I MHC mediated antigen processing & presentation R-HSA-983169
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Neutrophil degranulation R-HSA-6798695
Mitotic G1 phase and G1/S transition R-HSA-453279
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH4 R-HSA-9013694
Signaling by WNT R-HSA-195721
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular response to hypoxia R-HSA-1234174
MAPK1/MAPK3 signaling R-HSA-5684996
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle Checkpoints R-HSA-69620
ER-Phagosome pathway R-HSA-1236974
Transport of small molecules R-HSA-382551
Degradation of AXIN R-HSA-4641257
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Mitotic Anaphase R-HSA-68882
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of polyamines R-HSA-351202
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX2 R-HSA-8878166
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
C-type lectin receptors (CLRs) R-HSA-5621481
Beta-catenin independent WNT signaling R-HSA-3858494
Neddylation R-HSA-8951664
MAPK family signaling cascades R-HSA-5683057
Post-translational protein modification R-HSA-597592
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
S Phase R-HSA-69242
Regulation of PTEN stability and activity R-HSA-8948751
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Defective CFTR causes cystic fibrosis R-HSA-5678895
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RAS by GAPs R-HSA-5658442
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
ABC transporter disorders R-HSA-5619084
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
UCH proteinases R-HSA-5689603
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of PTEN stability and activity R-HSA-8948751
MAPK1/MAPK3 signaling R-HSA-5684996
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
HIV Infection R-HSA-162906
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle, Mitotic R-HSA-69278
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of AXIN R-HSA-4641257
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication Pre-Initiation R-HSA-69002
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Beta-catenin independent WNT signaling R-HSA-3858494
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Apoptosis R-HSA-109581
Signaling by ROBO receptors R-HSA-376176
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Nervous system development R-HSA-9675108
Mitotic G2-G2/M phases R-HSA-453274
TCR signaling R-HSA-202403
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'on' state R-HSA-5632684
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH R-HSA-157118
Hedgehog ligand biogenesis R-HSA-5358346
Transport of small molecules R-HSA-382551
Cyclin E associated events during G1/S transition R-HSA-69202
Metabolism of amino acids and derivatives R-HSA-71291
M Phase R-HSA-68886
Cellular responses to stress R-HSA-2262752
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Orc1 removal from chromatin R-HSA-68949
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX3 R-HSA-8878159
Class I MHC mediated antigen processing & presentation R-HSA-983169
Deubiquitination R-HSA-5688426
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
Separation of Sister Chromatids R-HSA-2467813
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Checkpoints R-HSA-69481
ER-Phagosome pathway R-HSA-1236974
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Neddylation R-HSA-8951664
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Post-translational protein modification R-HSA-597592
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of DVL R-HSA-4641258
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PTEN Regulation R-HSA-6807070
FCERI mediated NF-kB activation R-HSA-2871837
Defective CFTR causes cystic fibrosis R-HSA-5678895
Programmed Cell Death R-HSA-5357801
PCP/CE pathway R-HSA-4086400
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by WNT R-HSA-195721
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PIP3 activates AKT signaling R-HSA-1257604
G2/M Transition R-HSA-69275
Infectious disease R-HSA-5663205
C-type lectin receptors (CLRs) R-HSA-5621481
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Innate Immune System R-HSA-168249
Regulation of mitotic cell cycle R-HSA-453276
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cell Cycle Checkpoints R-HSA-69620
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Hedgehog R-HSA-5358351
Host Interactions of HIV factors R-HSA-162909
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of polyamines R-HSA-351202
Metabolism of RNA R-HSA-8953854
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Stabilization of p53 R-HSA-69541
Interleukin-1 signaling R-HSA-9020702
Asymmetric localization of PCP proteins R-HSA-4608870
Generic Transcription Pathway R-HSA-212436
G1/S Transition R-HSA-69206
Signal Transduction R-HSA-162582
DNA Replication R-HSA-69306
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
S Phase R-HSA-69242
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of proteins R-HSA-392499
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by NOTCH4 R-HSA-9013694
Switching of origins to a post-replicative state R-HSA-69052
Metabolism R-HSA-1430728
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transcriptional regulation by RUNX2 R-HSA-8878166
Hedgehog 'off' state R-HSA-5610787
Signaling by Interleukins R-HSA-449147
Vpu mediated degradation of CD4 R-HSA-180534
Developmental Biology R-HSA-1266738
CLEC7A (Dectin-1) signaling R-HSA-5607764
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Dependent G1 DNA Damage Response R-HSA-69563
Disease R-HSA-1643685
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Ub-specific processing proteases R-HSA-5689880
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing-Cross presentation R-HSA-1236975
Degradation of GLI1 by the proteasome R-HSA-5610780
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Synthesis of DNA R-HSA-69239
Adaptive Immune System R-HSA-1280218
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of DVL R-HSA-4641258
Antigen processing-Cross presentation R-HSA-1236975
Mitotic Metaphase and Anaphase R-HSA-2555396
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic G1 phase and G1/S transition R-HSA-453279
Separation of Sister Chromatids R-HSA-2467813
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic Anaphase R-HSA-68882
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Generic Transcription Pathway R-HSA-212436
Regulation of mitotic cell cycle R-HSA-453276
Infectious disease R-HSA-5663205
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of AXIN R-HSA-4641257
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX2 R-HSA-8878166
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stimuli R-HSA-8953897
Transport of small molecules R-HSA-382551
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transcriptional regulation by RUNX3 R-HSA-8878159
C-type lectin receptors (CLRs) R-HSA-5621481
Synthesis of DNA R-HSA-69239
Stabilization of p53 R-HSA-69541
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1 DNA Damage Response R-HSA-69563
Programmed Cell Death R-HSA-5357801
Cell Cycle, Mitotic R-HSA-69278
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Deubiquitination R-HSA-5688426
Cellular responses to stress R-HSA-2262752
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
Metabolism of polyamines R-HSA-351202
Cyclin E associated events during G1/S transition R-HSA-69202
Intracellular signaling by second messengers R-HSA-9006925
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
Downstream TCR signaling R-HSA-202424
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of RUNX2 expression and activity R-HSA-8939902
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCR signaling R-HSA-202403
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle R-HSA-1640170
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH4 R-HSA-9013694
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'on' state R-HSA-5632684
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vpu mediated degradation of CD4 R-HSA-180534
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to chemical stress R-HSA-9711123
KEAP1-NFE2L2 pathway R-HSA-9755511
Innate Immune System R-HSA-168249
Beta-catenin independent WNT signaling R-HSA-3858494
p53-Independent DNA Damage Response R-HSA-69610
Immune System R-HSA-168256
ABC transporter disorders R-HSA-5619084
Metabolism R-HSA-1430728
Degradation of GLI2 by the proteasome R-HSA-5610783
MAPK6/MAPK4 signaling R-HSA-5687128
Orc1 removal from chromatin R-HSA-68949
Gene expression (Transcription) R-HSA-74160
Neddylation R-HSA-8951664
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Post-translational protein modification R-HSA-597592
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Neutrophil degranulation R-HSA-6798695
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
MAPK family signaling cascades R-HSA-5683057
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G1/S Transition R-HSA-69206
Hh mutants abrogate ligand secretion R-HSA-5387390
DNA Replication R-HSA-69306
RAF/MAP kinase cascade R-HSA-5673001
Cytokine Signaling in Immune system R-HSA-1280215
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of proteins R-HSA-392499
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RAS by GAPs R-HSA-5658442
Hh mutants are degraded by ERAD R-HSA-5362768
Hedgehog ligand biogenesis R-HSA-5358346
PCP/CE pathway R-HSA-4086400
ABC-family proteins mediated transport R-HSA-382556
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to hypoxia R-HSA-1234174
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
Interleukin-1 signaling R-HSA-9020702
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle Checkpoints R-HSA-69620
S Phase R-HSA-69242
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by Interleukins R-HSA-449147
Switching of origins to a post-replicative state R-HSA-69052
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
HIV Infection R-HSA-162906
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ub-specific processing proteases R-HSA-5689880
DNA Replication Pre-Initiation R-HSA-69002
Nuclear events mediated by NFE2L2 R-HSA-9759194
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721

Expression Atlas ENSG00000165916
NCBI gene (formerly Entrezgene) 5702
GeneCards 9549
HGNC Symbol HGNC:9549
MIM gene 186852
MIM morbid 619354
UniProtKB Gene Name R4GNH3
WikiGene 5702
Gene: AGER
Ensembl ID : ENSG00000204305
Description: advanced glycosylation end-product specific receptor
Gene Synonyms: RAGE,SCARJ1,SRAGE
1 APIs:
170 Possible Orthologues:

Toll-like Receptor Cascades R-HSA-168898
Cytokine Signaling in Immune system R-HSA-1280215
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by Interleukins R-HSA-449147
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Interleukin-1 signaling R-HSA-9020702
Innate Immune System R-HSA-168249
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Immune System R-HSA-168256
Interleukin-1 family signaling R-HSA-446652
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Advanced glycosylation endproduct receptor signaling R-HSA-879415
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88 dependent cascade initiated on endosome R-HSA-975155
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Interleukin-1 signaling R-HSA-9020702
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Immune System R-HSA-168256
Interleukin-1 family signaling R-HSA-446652
Toll-like Receptor Cascades R-HSA-168898
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cytokine Signaling in Immune system R-HSA-1280215
TRAF6 mediated NF-kB activation R-HSA-933542
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Interleukin-1 signaling R-HSA-9020702
Immune System R-HSA-168256
Advanced glycosylation endproduct receptor signaling R-HSA-879415
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88 cascade initiated on plasma membrane R-HSA-975871
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by Interleukins R-HSA-449147
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88-independent TLR4 cascade R-HSA-166166
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cytokine Signaling in Immune system R-HSA-1280215
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Interleukin-1 signaling R-HSA-9020702
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRAF6 mediated NF-kB activation R-HSA-933542
Immune System R-HSA-168256
MyD88 cascade initiated on plasma membrane R-HSA-975871
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Interleukin-1 family signaling R-HSA-446652
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Interleukin-1 signaling R-HSA-9020702
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cytokine Signaling in Immune system R-HSA-1280215
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Interleukin-1 family signaling R-HSA-446652
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88-independent TLR4 cascade R-HSA-166166
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Interleukin-1 signaling R-HSA-9020702
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
MyD88-independent TLR4 cascade R-HSA-166166
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll-like Receptor Cascades R-HSA-168898
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRAF6 mediated NF-kB activation R-HSA-933542
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-1 signaling R-HSA-9020702
Toll-like Receptor Cascades R-HSA-168898
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88 dependent cascade initiated on endosome R-HSA-975155
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Innate Immune System R-HSA-168249
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88 cascade initiated on plasma membrane R-HSA-975871
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138

Expression Atlas ENSG00000204305
NCBI gene (formerly Entrezgene) 177
GeneCards 320
HGNC Symbol HGNC:320
MIM gene 600214
UniProtKB Gene Name Q5SSZ3
WikiGene 177
Gene: MCL1
Ensembl ID : ENSG00000143384
Description: MCL1 apoptosis regulator, BCL2 family member
Gene Synonyms: BCL2L3,MCL-1
1 APIs:
243 Possible Orthologues:

Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Immune System R-HSA-168256
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256

Expression Atlas ENSG00000143384
NCBI gene (formerly Entrezgene) 574406
GeneCards 6943
HGNC Symbol HGNC:6943
MIM gene 159552
UniProtKB Gene Name Q07820
WikiGene 574406