Gene: ACVRL1
Ensembl ID : ENSG00000139567
Description: activin A receptor like type 1
Gene Synonyms: ACVRLK1,ALK1,HHT,HHT2,ORW2
2 APIs:
358 Possible Orthologues:

Signal Transduction R-HSA-162582
Signaling by BMP R-HSA-201451
Signaling by TGFB family members R-HSA-9006936
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signaling by TGFB family members R-HSA-9006936
Signal Transduction R-HSA-162582
Signaling by BMP R-HSA-201451
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signal Transduction R-HSA-162582
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000139567
LRG display in Ensembl gene LRG_543
NCBI gene (formerly Entrezgene) 94
GeneCards 175
HGNC Symbol HGNC:175
MIM gene 601284
MIM morbid 600376
UniProtKB Gene Name P37023
WikiGene 94
Gene: INSR
Ensembl ID : ENSG00000171105
Description: insulin receptor
Gene Synonyms: CD220
36 APIs:
290 Possible Orthologues:

Signaling by Insulin receptor R-HSA-74752
PIP3 activates AKT signaling R-HSA-1257604
IRS activation R-HSA-74713
Signal attenuation R-HSA-74749
Insulin receptor recycling R-HSA-77387
Insulin receptor signalling cascade R-HSA-74751
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor recycling R-HSA-77387
IRS activation R-HSA-74713
Signaling by Insulin receptor R-HSA-74752
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
PIP3 activates AKT signaling R-HSA-1257604
Signal attenuation R-HSA-74749
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Insulin receptor signalling cascade R-HSA-74751
Signaling by Insulin receptor R-HSA-74752
Signal Transduction R-HSA-162582
Insulin receptor recycling R-HSA-77387
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal attenuation R-HSA-74749
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
IRS activation R-HSA-74713
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
Signaling by Insulin receptor R-HSA-74752
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
IRS activation R-HSA-74713
Negative regulation of the PI3K/AKT network R-HSA-199418
Insulin receptor recycling R-HSA-77387
Signal attenuation R-HSA-74749
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PIP3 activates AKT signaling R-HSA-1257604
Insulin receptor recycling R-HSA-77387
Signal attenuation R-HSA-74749
Insulin receptor signalling cascade R-HSA-74751
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Insulin receptor R-HSA-74752
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
PIP3 activates AKT signaling R-HSA-1257604
IRS activation R-HSA-74713
IRS activation R-HSA-74713
Signal Transduction R-HSA-162582
Insulin receptor signalling cascade R-HSA-74751
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Insulin receptor R-HSA-74752
Insulin receptor recycling R-HSA-77387
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal attenuation R-HSA-74749
PIP3 activates AKT signaling R-HSA-1257604
Insulin receptor signalling cascade R-HSA-74751
Signal attenuation R-HSA-74749
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS activation R-HSA-74713
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor recycling R-HSA-77387
Negative regulation of the PI3K/AKT network R-HSA-199418
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
Signal Transduction R-HSA-162582
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal attenuation R-HSA-74749
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IRS activation R-HSA-74713
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
Insulin receptor recycling R-HSA-77387
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal attenuation R-HSA-74749
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PIP3 activates AKT signaling R-HSA-1257604
Insulin receptor signalling cascade R-HSA-74751
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Insulin receptor recycling R-HSA-77387
IRS activation R-HSA-74713
Signaling by Insulin receptor R-HSA-74752

Expression Atlas ENSG00000171105
NCBI gene (formerly Entrezgene) 3643
GeneCards 6091
HGNC Symbol HGNC:6091
MIM gene 147670
MIM morbid 610549
UniProtKB Gene Name P06213
WikiGene 3643
Gene: AURKA
Ensembl ID : ENSG00000087586
Description: aurora kinase A
Gene Synonyms: AIK,ARK1,AURA,BTAK,PPP1R47,STK15,STK6,STK7
10 APIs:
229 Possible Orthologues:

APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Mitotic G2-G2/M phases R-HSA-453274
Interaction between PHLDA1 and AURKA R-HSA-8854521
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Regulation of TP53 Activity R-HSA-5633007
Gene expression (Transcription) R-HSA-74160
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
AURKA Activation by TPX2 R-HSA-8854518
Post-translational protein modification R-HSA-597592
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of mitotic cell cycle R-HSA-453276
RNA Polymerase II Transcription R-HSA-73857
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Interaction between PHLDA1 and AURKA R-HSA-8854521
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Transcriptional Regulation by TP53 R-HSA-3700989
Cell Cycle, Mitotic R-HSA-69278
AURKA Activation by TPX2 R-HSA-8854518
Regulation of TP53 Activity R-HSA-5633007
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
Mitotic G2-G2/M phases R-HSA-453274
Gene expression (Transcription) R-HSA-74160
SUMOylation of DNA replication proteins R-HSA-4615885
Post-translational protein modification R-HSA-597592
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
G2/M Transition R-HSA-69275
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G2/M Transition R-HSA-69275
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Interaction between PHLDA1 and AURKA R-HSA-8854521
Generic Transcription Pathway R-HSA-212436
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Transcriptional Regulation by TP53 R-HSA-3700989
Post-translational protein modification R-HSA-597592
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Cell Cycle R-HSA-1640170
SUMOylation of DNA replication proteins R-HSA-4615885
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G2-G2/M phases R-HSA-453274
SUMOylation R-HSA-2990846
AURKA Activation by TPX2 R-HSA-8854518
RNA Polymerase II Transcription R-HSA-73857
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cell Cycle, Mitotic R-HSA-69278
Regulation of TP53 Activity R-HSA-5633007
Regulation of mitotic cell cycle R-HSA-453276
AURKA Activation by TPX2 R-HSA-8854518
Interaction between PHLDA1 and AURKA R-HSA-8854521
Cell Cycle R-HSA-1640170
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation of DNA replication proteins R-HSA-4615885
Post-translational protein modification R-HSA-597592
Regulation of TP53 Activity R-HSA-5633007
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Cell Cycle, Mitotic R-HSA-69278
Metabolism of proteins R-HSA-392499
G2/M Transition R-HSA-69275
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by TP53 R-HSA-3700989
SUMOylation R-HSA-2990846
Gene expression (Transcription) R-HSA-74160
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
RNA Polymerase II Transcription R-HSA-73857
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Regulation of TP53 Activity R-HSA-5633007
AURKA Activation by TPX2 R-HSA-8854518
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Post-translational protein modification R-HSA-597592
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of mitotic cell cycle R-HSA-453276
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Cell Cycle R-HSA-1640170
Metabolism of proteins R-HSA-392499
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Mitotic G2-G2/M phases R-HSA-453274
G2/M Transition R-HSA-69275
Gene expression (Transcription) R-HSA-74160
Cell Cycle, Mitotic R-HSA-69278
SUMOylation R-HSA-2990846
Interaction between PHLDA1 and AURKA R-HSA-8854521
Transcriptional Regulation by TP53 R-HSA-3700989
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Metabolism of proteins R-HSA-392499
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Interaction between PHLDA1 and AURKA R-HSA-8854521
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Post-translational protein modification R-HSA-597592
SUMOylation of DNA replication proteins R-HSA-4615885
AURKA Activation by TPX2 R-HSA-8854518
Regulation of mitotic cell cycle R-HSA-453276
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SUMOylation R-HSA-2990846
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity R-HSA-5633007
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Mitotic G2-G2/M phases R-HSA-453274
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
AURKA Activation by TPX2 R-HSA-8854518
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Generic Transcription Pathway R-HSA-212436
Cell Cycle, Mitotic R-HSA-69278
Mitotic G2-G2/M phases R-HSA-453274
SUMOylation R-HSA-2990846
Transcriptional Regulation by TP53 R-HSA-3700989
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of TP53 Activity R-HSA-5633007
Metabolism of proteins R-HSA-392499
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Regulation of mitotic cell cycle R-HSA-453276
Interaction between PHLDA1 and AURKA R-HSA-8854521
G2/M Transition R-HSA-69275
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Metabolism of proteins R-HSA-392499
Interaction between PHLDA1 and AURKA R-HSA-8854521
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Post-translational protein modification R-HSA-597592
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of TP53 Activity R-HSA-5633007
G2/M Transition R-HSA-69275
Regulation of mitotic cell cycle R-HSA-453276
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AURKA Activation by TPX2 R-HSA-8854518
Transcriptional Regulation by TP53 R-HSA-3700989
Gene expression (Transcription) R-HSA-74160
SUMOylation R-HSA-2990846
Mitotic G2-G2/M phases R-HSA-453274
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
AURKA Activation by TPX2 R-HSA-8854518
RNA Polymerase II Transcription R-HSA-73857
Regulation of mitotic cell cycle R-HSA-453276
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G2/M Transition R-HSA-69275
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
SUMOylation R-HSA-2990846
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of TP53 Activity R-HSA-5633007
Interaction between PHLDA1 and AURKA R-HSA-8854521
Post-translational protein modification R-HSA-597592
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cell Cycle, Mitotic R-HSA-69278
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by TP53 R-HSA-3700989
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Cell Cycle R-HSA-1640170
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G2/M Transition R-HSA-69275
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of TP53 Activity R-HSA-5633007
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
RNA Polymerase II Transcription R-HSA-73857
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
AURKA Activation by TPX2 R-HSA-8854518
Interaction between PHLDA1 and AURKA R-HSA-8854521
SUMOylation R-HSA-2990846
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Metabolism of proteins R-HSA-392499
Regulation of mitotic cell cycle R-HSA-453276
Post-translational protein modification R-HSA-597592
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cell Cycle R-HSA-1640170
Post-translational protein modification R-HSA-597592
Gene expression (Transcription) R-HSA-74160
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of TP53 Activity R-HSA-5633007
Interaction between PHLDA1 and AURKA R-HSA-8854521
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic G2-G2/M phases R-HSA-453274
RNA Polymerase II Transcription R-HSA-73857
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle, Mitotic R-HSA-69278
Transcriptional Regulation by TP53 R-HSA-3700989
Metabolism of proteins R-HSA-392499
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
G2/M Transition R-HSA-69275
Generic Transcription Pathway R-HSA-212436
SUMOylation R-HSA-2990846
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
AURKA Activation by TPX2 R-HSA-8854518

Expression Atlas ENSG00000087586
NCBI gene (formerly Entrezgene) 6790
GeneCards 11393
HGNC Symbol HGNC:11393
MIM gene 603072
MIM morbid 114500
UniProtKB Gene Name Q5QPD4
WikiGene 6790
Gene: PARP2
Ensembl ID : ENSG00000129484
Description: poly(ADP-ribose) polymerase 2
Gene Synonyms: ADPRTL2,ARTD2
10 APIs:
186 Possible Orthologues:

DNA Repair R-HSA-73894
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Formation of Incision Complex in GG-NER R-HSA-5696395
Dual Incision in GG-NER R-HSA-5696400
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Resolution of Abasic Sites (AP sites) R-HSA-73933
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
DNA Damage Recognition in GG-NER R-HSA-5696394
Homology Directed Repair R-HSA-5693538
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Base Excision Repair R-HSA-73884
DNA Double-Strand Break Repair R-HSA-5693532
Nucleotide Excision Repair R-HSA-5696398
Nucleotide Excision Repair R-HSA-5696398
Formation of Incision Complex in GG-NER R-HSA-5696395
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Homology Directed Repair R-HSA-5693538
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
DNA Damage Recognition in GG-NER R-HSA-5696394
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Resolution of Abasic Sites (AP sites) R-HSA-73933
DNA Double-Strand Break Repair R-HSA-5693532
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Dual Incision in GG-NER R-HSA-5696400
DNA Repair R-HSA-73894
Base Excision Repair R-HSA-73884
DNA Damage Recognition in GG-NER R-HSA-5696394
Nucleotide Excision Repair R-HSA-5696398
Resolution of Abasic Sites (AP sites) R-HSA-73933
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Formation of Incision Complex in GG-NER R-HSA-5696395
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
DNA Double-Strand Break Repair R-HSA-5693532
Dual Incision in GG-NER R-HSA-5696400
Homology Directed Repair R-HSA-5693538
Base Excision Repair R-HSA-73884
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
DNA Repair R-HSA-73894
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Dual Incision in GG-NER R-HSA-5696400
DNA Double-Strand Break Repair R-HSA-5693532
DNA Repair R-HSA-73894
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Formation of Incision Complex in GG-NER R-HSA-5696395
Homology Directed Repair R-HSA-5693538
Resolution of Abasic Sites (AP sites) R-HSA-73933
Base Excision Repair R-HSA-73884
DNA Damage Recognition in GG-NER R-HSA-5696394
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Nucleotide Excision Repair R-HSA-5696398
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
DNA Repair R-HSA-73894
Resolution of Abasic Sites (AP sites) R-HSA-73933
DNA Damage Recognition in GG-NER R-HSA-5696394
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Formation of Incision Complex in GG-NER R-HSA-5696395
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Dual Incision in GG-NER R-HSA-5696400
Nucleotide Excision Repair R-HSA-5696398
Base Excision Repair R-HSA-73884
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Homology Directed Repair R-HSA-5693538
DNA Double-Strand Break Repair R-HSA-5693532
Resolution of Abasic Sites (AP sites) R-HSA-73933
DNA Damage Recognition in GG-NER R-HSA-5696394
DNA Double-Strand Break Repair R-HSA-5693532
Homology Directed Repair R-HSA-5693538
Nucleotide Excision Repair R-HSA-5696398
Dual Incision in GG-NER R-HSA-5696400
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Base Excision Repair R-HSA-73884
Formation of Incision Complex in GG-NER R-HSA-5696395
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
DNA Repair R-HSA-73894
Base Excision Repair R-HSA-73884
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Formation of Incision Complex in GG-NER R-HSA-5696395
DNA Damage Recognition in GG-NER R-HSA-5696394
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Homology Directed Repair R-HSA-5693538
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Resolution of Abasic Sites (AP sites) R-HSA-73933
Dual Incision in GG-NER R-HSA-5696400
DNA Repair R-HSA-73894
Nucleotide Excision Repair R-HSA-5696398
DNA Double-Strand Break Repair R-HSA-5693532
DNA Repair R-HSA-73894
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Resolution of Abasic Sites (AP sites) R-HSA-73933
DNA Damage Recognition in GG-NER R-HSA-5696394
Dual Incision in GG-NER R-HSA-5696400
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Base Excision Repair R-HSA-73884
Formation of Incision Complex in GG-NER R-HSA-5696395
DNA Double-Strand Break Repair R-HSA-5693532
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Homology Directed Repair R-HSA-5693538
Nucleotide Excision Repair R-HSA-5696398
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
DNA Double-Strand Break Repair R-HSA-5693532
Base Excision Repair R-HSA-73884
Homology Directed Repair R-HSA-5693538
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Nucleotide Excision Repair R-HSA-5696398
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
DNA Damage Recognition in GG-NER R-HSA-5696394
Dual Incision in GG-NER R-HSA-5696400
DNA Repair R-HSA-73894
Resolution of Abasic Sites (AP sites) R-HSA-73933
Formation of Incision Complex in GG-NER R-HSA-5696395
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
DNA Double-Strand Break Repair R-HSA-5693532
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
DNA Damage Recognition in GG-NER R-HSA-5696394
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Homology Directed Repair R-HSA-5693538
Nucleotide Excision Repair R-HSA-5696398
Resolution of Abasic Sites (AP sites) R-HSA-73933
Base Excision Repair R-HSA-73884
DNA Repair R-HSA-73894
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Formation of Incision Complex in GG-NER R-HSA-5696395
Dual Incision in GG-NER R-HSA-5696400

Expression Atlas ENSG00000129484
NCBI gene (formerly Entrezgene) 10038
GeneCards 272
HGNC Symbol HGNC:272
MIM gene 607725
UniProtKB Gene Name Q9UGN5
WikiGene 10038
Gene: PIK3CA
Ensembl ID : ENSG00000121879
Description: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Gene Synonyms: PI3K
36 APIs:
272 Possible Orthologues:

Hemostasis R-HSA-109582
PI3K Cascade R-HSA-109704
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by EGFRvIII in Cancer R-HSA-5637812
Signaling by Insulin receptor R-HSA-74752
IRS-mediated signalling R-HSA-112399
Activated NTRK3 signals through PI3K R-HSA-9603381
RAC1 GTPase cycle R-HSA-9013149
Signaling by NTRK2 (TRKB) R-HSA-9006115
VEGFA-VEGFR2 Pathway R-HSA-4420097
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by ERBB2 in Cancer R-HSA-1227990
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by ALK fusions and activated point mutants R-HSA-9725370
PI-3K cascade:FGFR3 R-HSA-5654710
Hemostasis R-HSA-109582
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Signaling by FGFR2 R-HSA-5654738
Interleukin receptor SHC signaling R-HSA-912526
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by FGFR1 in disease R-HSA-5655302
IGF1R signaling cascade R-HSA-2428924
Interleukin-2 family signaling R-HSA-451927
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by NTRK1 (TRKA) R-HSA-187037
Role of phospholipids in phagocytosis R-HSA-2029485
RET signaling R-HSA-8853659
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
PI-3K cascade:FGFR2 R-HSA-5654695
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by NTRK3 (TRKC) R-HSA-9034015
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
RAF/MAP kinase cascade R-HSA-5673001
Phospholipid metabolism R-HSA-1483257
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by Interleukins R-HSA-449147
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PI-3K cascade:FGFR1 R-HSA-5654689
Downstream TCR signaling R-HSA-202424
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by ALK R-HSA-201556
CD28 co-stimulation R-HSA-389356
Disease R-HSA-1643685
Nephrin family interactions R-HSA-373753
PI3K events in ERBB2 signaling R-HSA-1963642
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
ESR-mediated signaling R-HSA-8939211
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by SCF-KIT R-HSA-1433557
Signaling by ALK in cancer R-HSA-9700206
PI3K Cascade R-HSA-109704
MET activates PI3K/AKT signaling R-HSA-8851907
DAP12 interactions R-HSA-2172127
Regulation of signaling by CBL R-HSA-912631
PI-3K cascade:FGFR4 R-HSA-5654720
Signaling by Rho GTPases R-HSA-194315
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
DAP12 signaling R-HSA-2424491
Signaling by MET R-HSA-6806834
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by FGFR R-HSA-190236
RAC2 GTPase cycle R-HSA-9013404
GPVI-mediated activation cascade R-HSA-114604
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by PDGFR in disease R-HSA-9671555
Signaling by EGFR in Cancer R-HSA-1643713
GAB1 signalosome R-HSA-180292
Signaling by NTRKs R-HSA-166520
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR in disease R-HSA-1226099
RHO GTPase cycle R-HSA-9012999
Axon guidance R-HSA-422475
Signaling by FGFR1 R-HSA-5654736
Immune System R-HSA-168256
Signaling by ERBB4 R-HSA-1236394
Downstream signaling of activated FGFR1 R-HSA-5654687
FLT3 signaling in disease R-HSA-9682385
TCR signaling R-HSA-202403
Signaling by FGFR3 R-HSA-5654741
Signaling by Erythropoietin R-HSA-9006335
FLT3 Signaling R-HSA-9607240
Cell-Cell communication R-HSA-1500931
PI3K events in ERBB4 signaling R-HSA-1250342
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Activated NTRK2 signals through PI3K R-HSA-9028335
G alpha (q) signalling events R-HSA-416476
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Extra-nuclear estrogen signaling R-HSA-9009391
Costimulation by the CD28 family R-HSA-388841
Signaling by FGFR2 in disease R-HSA-5655253
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by FLT3 fusion proteins R-HSA-9703465
CD28 dependent PI3K/Akt signaling R-HSA-389357
MAPK1/MAPK3 signaling R-HSA-5684996
Nervous system development R-HSA-9675108
GPCR downstream signalling R-HSA-388396
Intracellular signaling by second messengers R-HSA-9006925
Signaling by GPCR R-HSA-372790
Tie2 Signaling R-HSA-210993
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by KIT in disease R-HSA-9669938
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by PDGF R-HSA-186797
Downstream signal transduction R-HSA-186763
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
Signaling by ERBB2 R-HSA-1227986
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by FGFR3 in disease R-HSA-5655332
Signaling by EGFR R-HSA-177929
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Insulin receptor signalling cascade R-HSA-74751
PIP3 activates AKT signaling R-HSA-1257604
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by FGFR4 R-HSA-5654743
Developmental Biology R-HSA-1266738
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
PI3K/AKT activation R-HSA-198203
PI Metabolism R-HSA-1483255
Metabolism of lipids R-HSA-556833
Signaling by VEGF R-HSA-194138
PI-3K cascade:FGFR1 R-HSA-5654689
Adaptive Immune System R-HSA-1280218
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by GPCR R-HSA-372790
Signaling by KIT in disease R-HSA-9669938
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by ALK in cancer R-HSA-9700206
Signaling by Insulin receptor R-HSA-74752
Signaling by PDGFR in disease R-HSA-9671555
CD28 dependent PI3K/Akt signaling R-HSA-389357
PI3K/AKT activation R-HSA-198203
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by NTRK2 (TRKB) R-HSA-9006115
PI3K events in ERBB2 signaling R-HSA-1963642
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by ERBB2 R-HSA-1227986
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by ERBB2 in Cancer R-HSA-1227990
Immune System R-HSA-168256
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Downstream signaling of activated FGFR2 R-HSA-5654696
DAP12 interactions R-HSA-2172127
Signaling by Rho GTPases R-HSA-194315
FLT3 Signaling R-HSA-9607240
Metabolism of lipids R-HSA-556833
Signaling by FGFR4 R-HSA-5654743
GPVI-mediated activation cascade R-HSA-114604
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
DAP12 signaling R-HSA-2424491
FLT3 signaling in disease R-HSA-9682385
Signaling by ALK fusions and activated point mutants R-HSA-9725370
PI3K events in ERBB4 signaling R-HSA-1250342
PI Metabolism R-HSA-1483255
Activated NTRK3 signals through PI3K R-HSA-9603381
IGF1R signaling cascade R-HSA-2428924
ESR-mediated signaling R-HSA-8939211
Downstream signaling of activated FGFR3 R-HSA-5654708
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
Signaling by PDGF R-HSA-186797
Signaling by FGFR4 in disease R-HSA-5655291
GAB1 signalosome R-HSA-180292
Disease R-HSA-1643685
Regulation of signaling by CBL R-HSA-912631
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Costimulation by the CD28 family R-HSA-388841
Signaling by SCF-KIT R-HSA-1433557
Signaling by FGFR R-HSA-190236
Developmental Biology R-HSA-1266738
Signaling by NTRKs R-HSA-166520
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Intracellular signaling by second messengers R-HSA-9006925
Tie2 Signaling R-HSA-210993
Activated NTRK2 signals through PI3K R-HSA-9028335
RET signaling R-HSA-8853659
Downstream TCR signaling R-HSA-202424
GPCR downstream signalling R-HSA-388396
MAPK1/MAPK3 signaling R-HSA-5684996
Role of phospholipids in phagocytosis R-HSA-2029485
CD28 co-stimulation R-HSA-389356
VEGFA-VEGFR2 Pathway R-HSA-4420097
TCR signaling R-HSA-202403
Interleukin receptor SHC signaling R-HSA-912526
Signaling by EGFRvIII in Cancer R-HSA-5637812
RAC1 GTPase cycle R-HSA-9013149
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Insulin receptor signalling cascade R-HSA-74751
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by FGFR3 in disease R-HSA-5655332
RHO GTPase cycle R-HSA-9012999
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by Nuclear Receptors R-HSA-9006931
PIP3 activates AKT signaling R-HSA-1257604
Signaling by NTRK3 (TRKC) R-HSA-9034015
Innate Immune System R-HSA-168249
Phospholipid metabolism R-HSA-1483257
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by FGFR in disease R-HSA-1226099
Signaling by MET R-HSA-6806834
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by FGFR1 R-HSA-5654736
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Cell-Cell communication R-HSA-1500931
IRS-related events triggered by IGF1R R-HSA-2428928
Nervous system development R-HSA-9675108
Interleukin-2 family signaling R-HSA-451927
Signaling by Interleukins R-HSA-449147
Negative regulation of the PI3K/AKT network R-HSA-199418
Nephrin family interactions R-HSA-373753
Cytokine Signaling in Immune system R-HSA-1280215
Platelet activation, signaling and aggregation R-HSA-76002
IRS-mediated signalling R-HSA-112399
Signal Transduction R-HSA-162582
Signaling by ERBB4 R-HSA-1236394
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism R-HSA-1430728
Signaling by EGFR R-HSA-177929
PI3K Cascade R-HSA-109704
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by ALK R-HSA-201556
FGFR1 mutant receptor activation R-HSA-1839124
MAPK family signaling cascades R-HSA-5683057
Extra-nuclear estrogen signaling R-HSA-9009391
Downstream signal transduction R-HSA-186763
Constitutive Signaling by EGFRvIII R-HSA-5637810
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by FLT3 fusion proteins R-HSA-9703465
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by FGFR2 R-HSA-5654738
Signaling by ERBB2 KD Mutants R-HSA-9664565
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
PI-3K cascade:FGFR3 R-HSA-5654710
PI-3K cascade:FGFR4 R-HSA-5654720
Signaling by FGFR3 R-HSA-5654741
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by VEGF R-HSA-194138
RAC2 GTPase cycle R-HSA-9013404
G alpha (q) signalling events R-HSA-416476
Signaling by Erythropoietin R-HSA-9006335
MET activates PI3K/AKT signaling R-HSA-8851907
Signaling by FGFR in disease R-HSA-1226099
Signaling by ALK in cancer R-HSA-9700206
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by FGFR4 in disease R-HSA-5655291
Cell surface interactions at the vascular wall R-HSA-202733
DAP12 signaling R-HSA-2424491
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by ALK R-HSA-201556
Metabolism of lipids R-HSA-556833
MAPK family signaling cascades R-HSA-5683057
PI-3K cascade:FGFR2 R-HSA-5654695
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by ERBB4 R-HSA-1236394
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by FGFR R-HSA-190236
Cytokine Signaling in Immune system R-HSA-1280215
TCR signaling R-HSA-202403
CD28 dependent PI3K/Akt signaling R-HSA-389357
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by GPCR R-HSA-372790
Downstream TCR signaling R-HSA-202424
Signaling by ERBB2 ECD mutants R-HSA-9665348
FLT3 Signaling R-HSA-9607240
Signaling by EGFR R-HSA-177929
PI3K/AKT Signaling in Cancer R-HSA-2219528
Immune System R-HSA-168256
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by PDGF R-HSA-186797
Adaptive Immune System R-HSA-1280218
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by FGFR2 R-HSA-5654738
Signaling by FLT3 fusion proteins R-HSA-9703465
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
G alpha (q) signalling events R-HSA-416476
Signaling by Rho GTPases R-HSA-194315
PI Metabolism R-HSA-1483255
Phospholipid metabolism R-HSA-1483257
FLT3 signaling in disease R-HSA-9682385
Interleukin receptor SHC signaling R-HSA-912526
RET signaling R-HSA-8853659
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by FGFR3 in disease R-HSA-5655332
Nervous system development R-HSA-9675108
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by EGFRvIII in Cancer R-HSA-5637812
Constitutive Signaling by EGFRvIII R-HSA-5637810
IGF1R signaling cascade R-HSA-2428924
GAB1 signalosome R-HSA-180292
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
RHO GTPase cycle R-HSA-9012999
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PI-3K cascade:FGFR4 R-HSA-5654720
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by MET R-HSA-6806834
Downstream signal transduction R-HSA-186763
Signaling by NTRK3 (TRKC) R-HSA-9034015
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by VEGF R-HSA-194138
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by FGFR1 R-HSA-5654736
Cell-Cell communication R-HSA-1500931
Signaling by FGFR4 R-HSA-5654743
Signal Transduction R-HSA-162582
Signaling by ERBB2 R-HSA-1227986
Role of phospholipids in phagocytosis R-HSA-2029485
IRS-mediated signalling R-HSA-112399
Signaling by Interleukins R-HSA-449147
Signaling by Erythropoietin R-HSA-9006335
Activated NTRK2 signals through PI3K R-HSA-9028335
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Signaling by KIT in disease R-HSA-9669938
MET activates PI3K/AKT signaling R-HSA-8851907
RAF/MAP kinase cascade R-HSA-5673001
GPCR downstream signalling R-HSA-388396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Axon guidance R-HSA-422475
Hemostasis R-HSA-109582
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by NTRKs R-HSA-166520
Signaling by PDGFR in disease R-HSA-9671555
Intracellular signaling by second messengers R-HSA-9006925
Regulation of signaling by CBL R-HSA-912631
ESR-mediated signaling R-HSA-8939211
Developmental Biology R-HSA-1266738
Signaling by SCF-KIT R-HSA-1433557
GPVI-mediated activation cascade R-HSA-114604
DAP12 interactions R-HSA-2172127
CD28 co-stimulation R-HSA-389356
Costimulation by the CD28 family R-HSA-388841
Platelet activation, signaling and aggregation R-HSA-76002
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
RAC2 GTPase cycle R-HSA-9013404
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
PI3K/AKT activation R-HSA-198203
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Insulin receptor R-HSA-74752
Nephrin family interactions R-HSA-373753
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Interleukin-2 family signaling R-HSA-451927
Downstream signaling of activated FGFR2 R-HSA-5654696
Activated NTRK3 signals through PI3K R-HSA-9603381
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
PI3K Cascade R-HSA-109704
PI3K events in ERBB4 signaling R-HSA-1250342
PI-3K cascade:FGFR3 R-HSA-5654710
Synthesis of PIPs at the plasma membrane R-HSA-1660499
RAC1 GTPase cycle R-HSA-9013149
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by FGFR2 in disease R-HSA-5655253
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by NTRK2 (TRKB) R-HSA-9006115
Signaling by EGFR in Cancer R-HSA-1643713
Insulin receptor signalling cascade R-HSA-74751
Tie2 Signaling R-HSA-210993
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by FGFR3 R-HSA-5654741
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Metabolism R-HSA-1430728
PI3K events in ERBB2 signaling R-HSA-1963642
Disease R-HSA-1643685
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by ERBB2 KD Mutants R-HSA-9664565
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR3 R-HSA-5654741
Downstream signal transduction R-HSA-186763
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by FGFR4 in disease R-HSA-5655291
Downstream signaling of activated FGFR1 R-HSA-5654687
FLT3 Signaling R-HSA-9607240
Downstream TCR signaling R-HSA-202424
CD28 dependent PI3K/Akt signaling R-HSA-389357
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Signaling by KIT in disease R-HSA-9669938
Signaling by FLT3 fusion proteins R-HSA-9703465
Signaling by FGFR1 in disease R-HSA-5655302
Developmental Biology R-HSA-1266738
Signaling by PDGF R-HSA-186797
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Signaling by FGFR3 in disease R-HSA-5655332
Signal Transduction R-HSA-162582
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by SCF-KIT R-HSA-1433557
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MAPK family signaling cascades R-HSA-5683057
Disease R-HSA-1643685
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by FGFR4 R-HSA-5654743
FLT3 signaling in disease R-HSA-9682385
FGFR1 mutant receptor activation R-HSA-1839124
IRS-mediated signalling R-HSA-112399
Axon guidance R-HSA-422475
Downstream signaling of activated FGFR4 R-HSA-5654716
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Tie2 Signaling R-HSA-210993
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Costimulation by the CD28 family R-HSA-388841
Signaling by PDGFR in disease R-HSA-9671555
Role of phospholipids in phagocytosis R-HSA-2029485
Negative regulation of the PI3K/AKT network R-HSA-199418
G alpha (q) signalling events R-HSA-416476
Signaling by FGFR2 in disease R-HSA-5655253
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ALK in cancer R-HSA-9700206
Interleukin-2 family signaling R-HSA-451927
Signaling by EGFR R-HSA-177929
DAP12 interactions R-HSA-2172127
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
RAC1 GTPase cycle R-HSA-9013149
PI3K Cascade R-HSA-109704
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by FGFR R-HSA-190236
Nephrin family interactions R-HSA-373753
Interleukin receptor SHC signaling R-HSA-912526
RHO GTPase cycle R-HSA-9012999
Signaling by EGFRvIII in Cancer R-HSA-5637812
TCR signaling R-HSA-202403
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by NTRK3 (TRKC) R-HSA-9034015
RAC2 GTPase cycle R-HSA-9013404
Nervous system development R-HSA-9675108
GPVI-mediated activation cascade R-HSA-114604
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
GPCR downstream signalling R-HSA-388396
Signaling by ALK fusions and activated point mutants R-HSA-9725370
PI-3K cascade:FGFR4 R-HSA-5654720
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
DAP12 signaling R-HSA-2424491
Signaling by NTRKs R-HSA-166520
Insulin receptor signalling cascade R-HSA-74751
Signaling by GPCR R-HSA-372790
Signaling by ERBB4 R-HSA-1236394
Signaling by ALK R-HSA-201556
Signaling by Interleukins R-HSA-449147
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Signaling by FGFR in disease R-HSA-1226099
CD28 co-stimulation R-HSA-389356
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by NTRK2 (TRKB) R-HSA-9006115
GAB1 signalosome R-HSA-180292
Signaling by NTRK1 (TRKA) R-HSA-187037
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR1 R-HSA-5654736
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IRS-related events triggered by IGF1R R-HSA-2428928
RET signaling R-HSA-8853659
Downstream signaling of activated FGFR2 R-HSA-5654696
Constitutive Signaling by EGFRvIII R-HSA-5637810
Downstream signaling of activated FGFR3 R-HSA-5654708
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR2 R-HSA-5654738
Signaling by EGFR in Cancer R-HSA-1643713
PI-3K cascade:FGFR1 R-HSA-5654689
Activated NTRK3 signals through PI3K R-HSA-9603381
PI-3K cascade:FGFR3 R-HSA-5654710
Signaling by ERBB2 R-HSA-1227986
Signaling by VEGF R-HSA-194138
Hemostasis R-HSA-109582
RAF/MAP kinase cascade R-HSA-5673001
PI3K events in ERBB4 signaling R-HSA-1250342
Signaling by Erythropoietin R-HSA-9006335
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by MET R-HSA-6806834
PIP3 activates AKT signaling R-HSA-1257604
Cell-Cell communication R-HSA-1500931
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by Rho GTPases R-HSA-194315
IGF1R signaling cascade R-HSA-2428924
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI Metabolism R-HSA-1483255
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by ERBB2 ECD mutants R-HSA-9665348
Phospholipid metabolism R-HSA-1483257
PI3K/AKT activation R-HSA-198203
ESR-mediated signaling R-HSA-8939211
Signaling by Nuclear Receptors R-HSA-9006931
PI3K events in ERBB2 signaling R-HSA-1963642
Regulation of signaling by CBL R-HSA-912631
MET activates PI3K/AKT signaling R-HSA-8851907
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by FGFR2 R-HSA-5654738
Signaling by NTRK2 (TRKB) R-HSA-9006115
RAC1 GTPase cycle R-HSA-9013149
DAP12 interactions R-HSA-2172127
Signaling by Nuclear Receptors R-HSA-9006931
VEGFA-VEGFR2 Pathway R-HSA-4420097
FGFR1 mutant receptor activation R-HSA-1839124
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Role of phospholipids in phagocytosis R-HSA-2029485
Hemostasis R-HSA-109582
Disease R-HSA-1643685
Innate Immune System R-HSA-168249
RET signaling R-HSA-8853659
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MET activates PI3K/AKT signaling R-HSA-8851907
FLT3 Signaling R-HSA-9607240
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by FGFR1 in disease R-HSA-5655302
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by ERBB2 ECD mutants R-HSA-9665348
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Rho GTPases R-HSA-194315
Signaling by FGFR1 R-HSA-5654736
MAPK family signaling cascades R-HSA-5683057
Signaling by ERBB2 in Cancer R-HSA-1227990
Signal Transduction R-HSA-162582
Signaling by Insulin receptor R-HSA-74752
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Interleukin-2 family signaling R-HSA-451927
PI-3K cascade:FGFR1 R-HSA-5654689
GPCR downstream signalling R-HSA-388396
CD28 dependent PI3K/Akt signaling R-HSA-389357
Insulin receptor signalling cascade R-HSA-74751
Platelet activation, signaling and aggregation R-HSA-76002
IGF1R signaling cascade R-HSA-2428924
MAPK1/MAPK3 signaling R-HSA-5684996
PI-3K cascade:FGFR3 R-HSA-5654710
Signaling by ERBB2 R-HSA-1227986
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by FGFR3 R-HSA-5654741
Regulation of signaling by CBL R-HSA-912631
Immune System R-HSA-168256
Signaling by NTRK3 (TRKC) R-HSA-9034015
Signaling by ALK in cancer R-HSA-9700206
Signaling by ALK R-HSA-201556
Cell-Cell communication R-HSA-1500931
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K events in ERBB4 signaling R-HSA-1250342
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by PDGFR in disease R-HSA-9671555
Signaling by PDGF R-HSA-186797
Signaling by KIT in disease R-HSA-9669938
Signaling by ERBB2 KD Mutants R-HSA-9664565
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by GPCR R-HSA-372790
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
PI3K/AKT activation R-HSA-198203
Developmental Biology R-HSA-1266738
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
RAC2 GTPase cycle R-HSA-9013404
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signal transduction R-HSA-186763
Signaling by Interleukins R-HSA-449147
IRS-related events triggered by IGF1R R-HSA-2428928
CD28 co-stimulation R-HSA-389356
Signaling by FGFR2 in disease R-HSA-5655253
Metabolism of lipids R-HSA-556833
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Adaptive Immune System R-HSA-1280218
Signaling by NTRK1 (TRKA) R-HSA-187037
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Axon guidance R-HSA-422475
Signaling by EGFR R-HSA-177929
GPVI-mediated activation cascade R-HSA-114604
FLT3 signaling in disease R-HSA-9682385
Signaling by FGFR4 R-HSA-5654743
Nephrin family interactions R-HSA-373753
Signaling by FGFR3 in disease R-HSA-5655332
Nervous system development R-HSA-9675108
G alpha (q) signalling events R-HSA-416476
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by FLT3 fusion proteins R-HSA-9703465
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Costimulation by the CD28 family R-HSA-388841
Activated NTRK3 signals through PI3K R-HSA-9603381
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
TCR signaling R-HSA-202403
Downstream signaling of activated FGFR4 R-HSA-5654716
PI Metabolism R-HSA-1483255
Signaling by FGFR R-HSA-190236
PIP3 activates AKT signaling R-HSA-1257604
Signaling by SCF-KIT R-HSA-1433557
GAB1 signalosome R-HSA-180292
IRS-mediated signalling R-HSA-112399
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by VEGF R-HSA-194138
Tie2 Signaling R-HSA-210993
Signaling by MET R-HSA-6806834
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Extra-nuclear estrogen signaling R-HSA-9009391
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Intracellular signaling by second messengers R-HSA-9006925
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Signaling by EGFRvIII in Cancer R-HSA-5637812
PI3K Cascade R-HSA-109704
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Phospholipid metabolism R-HSA-1483257
Downstream TCR signaling R-HSA-202424
PI-3K cascade:FGFR4 R-HSA-5654720
Signaling by NTRKs R-HSA-166520
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Interleukin receptor SHC signaling R-HSA-912526
DAP12 signaling R-HSA-2424491
Signaling by Erythropoietin R-HSA-9006335
RHO GTPase cycle R-HSA-9012999
ESR-mediated signaling R-HSA-8939211
Signaling by FGFR in disease R-HSA-1226099
Cell surface interactions at the vascular wall R-HSA-202733
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by EGFR R-HSA-177929
Signaling by PDGF R-HSA-186797
Metabolism R-HSA-1430728
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by FGFR1 in disease R-HSA-5655302
PIP3 activates AKT signaling R-HSA-1257604
Activated NTRK3 signals through PI3K R-HSA-9603381
Role of phospholipids in phagocytosis R-HSA-2029485
Adaptive Immune System R-HSA-1280218
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
MAPK family signaling cascades R-HSA-5683057
Signaling by NTRK1 (TRKA) R-HSA-187037
Signal Transduction R-HSA-162582
PI-3K cascade:FGFR4 R-HSA-5654720
ESR-mediated signaling R-HSA-8939211
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by ALK R-HSA-201556
Cell surface interactions at the vascular wall R-HSA-202733
Costimulation by the CD28 family R-HSA-388841
Signaling by ALK in cancer R-HSA-9700206
Signaling by ERBB2 R-HSA-1227986
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by GPCR R-HSA-372790
DAP12 interactions R-HSA-2172127
Signaling by VEGF R-HSA-194138
Metabolism of lipids R-HSA-556833
Signaling by FGFR1 R-HSA-5654736
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by EGFR in Cancer R-HSA-1643713
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by Erythropoietin R-HSA-9006335
Signaling by FGFR in disease R-HSA-1226099
Signaling by FGFR3 R-HSA-5654741
Intracellular signaling by second messengers R-HSA-9006925
PI Metabolism R-HSA-1483255
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
RAF/MAP kinase cascade R-HSA-5673001
IRS-mediated signalling R-HSA-112399
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Disease R-HSA-1643685
FLT3 Signaling R-HSA-9607240
DAP12 signaling R-HSA-2424491
Interleukin receptor SHC signaling R-HSA-912526
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by NTRK3 (TRKC) R-HSA-9034015
FGFR1 mutant receptor activation R-HSA-1839124
Cell-Cell communication R-HSA-1500931
Hemostasis R-HSA-109582
RAC1 GTPase cycle R-HSA-9013149
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by FGFR4 R-HSA-5654743
Developmental Biology R-HSA-1266738
PI3K Cascade R-HSA-109704
PI3K events in ERBB4 signaling R-HSA-1250342
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Cytokine Signaling in Immune system R-HSA-1280215
Nephrin family interactions R-HSA-373753
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
FLT3 signaling in disease R-HSA-9682385
IGF1R signaling cascade R-HSA-2428924
Signaling by ERBB4 R-HSA-1236394
Immune System R-HSA-168256
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by NTRK2 (TRKB) R-HSA-9006115
RET signaling R-HSA-8853659
IRS-related events triggered by IGF1R R-HSA-2428928
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by FLT3 fusion proteins R-HSA-9703465
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by NTRKs R-HSA-166520
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by SCF-KIT R-HSA-1433557
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by PDGFR in disease R-HSA-9671555
PI-3K cascade:FGFR3 R-HSA-5654710
G alpha (q) signalling events R-HSA-416476
RAC2 GTPase cycle R-HSA-9013404
Signaling by MET R-HSA-6806834
Signaling by Nuclear Receptors R-HSA-9006931
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Rho GTPases R-HSA-194315
GPCR downstream signalling R-HSA-388396
Signaling by FGFR2 R-HSA-5654738
Innate Immune System R-HSA-168249
Interleukin-2 family signaling R-HSA-451927
Downstream signaling of activated FGFR3 R-HSA-5654708
Downstream signaling of activated FGFR1 R-HSA-5654687
MET activates PI3K/AKT signaling R-HSA-8851907
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by Insulin receptor R-HSA-74752
RHO GTPase cycle R-HSA-9012999
Signaling by ERBB2 in Cancer R-HSA-1227990
CD28 co-stimulation R-HSA-389356
Activated NTRK2 signals through PI3K R-HSA-9028335
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Interleukins R-HSA-449147
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR3 in disease R-HSA-5655332
Downstream signal transduction R-HSA-186763
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR2 in disease R-HSA-5655253
GPVI-mediated activation cascade R-HSA-114604
Constitutive Signaling by EGFRvIII R-HSA-5637810
Nervous system development R-HSA-9675108
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by FGFR R-HSA-190236
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by ERBB2 ECD mutants R-HSA-9665348
Tie2 Signaling R-HSA-210993
Signaling by EGFRvIII in Cancer R-HSA-5637812
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by FGFR4 in disease R-HSA-5655291
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of signaling by CBL R-HSA-912631
Axon guidance R-HSA-422475
Signaling by KIT in disease R-HSA-9669938
Insulin receptor signalling cascade R-HSA-74751
Phospholipid metabolism R-HSA-1483257
Signaling by ERBB2 KD Mutants R-HSA-9664565
PI3K/AKT activation R-HSA-198203
Downstream TCR signaling R-HSA-202424
GAB1 signalosome R-HSA-180292
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Signaling by ALK in cancer R-HSA-9700206
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by ERBB2 ECD mutants R-HSA-9665348
Role of phospholipids in phagocytosis R-HSA-2029485
Signaling by Insulin receptor R-HSA-74752
PI-3K cascade:FGFR1 R-HSA-5654689
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by Erythropoietin R-HSA-9006335
G alpha (q) signalling events R-HSA-416476
Signaling by EGFR in Cancer R-HSA-1643713
Downstream signaling of activated FGFR1 R-HSA-5654687
GAB1 signalosome R-HSA-180292
Cell surface interactions at the vascular wall R-HSA-202733
Downstream signaling of activated FGFR2 R-HSA-5654696
PI3K Cascade R-HSA-109704
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signal transduction R-HSA-186763
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Hemostasis R-HSA-109582
PI-3K cascade:FGFR4 R-HSA-5654720
RHO GTPase cycle R-HSA-9012999
IGF1R signaling cascade R-HSA-2428924
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by FGFR3 in disease R-HSA-5655332
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
DAP12 signaling R-HSA-2424491
RAC1 GTPase cycle R-HSA-9013149
Signaling by SCF-KIT R-HSA-1433557
DAP12 interactions R-HSA-2172127
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR in disease R-HSA-1226099
RAC2 GTPase cycle R-HSA-9013404
Nephrin family interactions R-HSA-373753
Downstream TCR signaling R-HSA-202424
Signaling by ALK R-HSA-201556
Signaling by Interleukins R-HSA-449147
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NTRK3 (TRKC) R-HSA-9034015
Costimulation by the CD28 family R-HSA-388841
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR2 in disease R-HSA-5655253
Interleukin-2 family signaling R-HSA-451927
Signaling by FGFR4 R-HSA-5654743
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
RET signaling R-HSA-8853659
PI3K events in ERBB2 signaling R-HSA-1963642
Interleukin receptor SHC signaling R-HSA-912526
IRS-related events triggered by IGF1R R-HSA-2428928
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by FGFR R-HSA-190236
Signaling by PDGF R-HSA-186797
Signaling by ERBB2 R-HSA-1227986
PIP3 activates AKT signaling R-HSA-1257604
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by ERBB2 KD Mutants R-HSA-9664565
Adaptive Immune System R-HSA-1280218
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
MET activates PI3K/AKT signaling R-HSA-8851907
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Insulin receptor signalling cascade R-HSA-74751
IRS-mediated signalling R-HSA-112399
PI3K events in ERBB4 signaling R-HSA-1250342
Signaling by PDGFR in disease R-HSA-9671555
Axon guidance R-HSA-422475
Activated NTRK2 signals through PI3K R-HSA-9028335
Phospholipid metabolism R-HSA-1483257
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by VEGF R-HSA-194138
Tie2 Signaling R-HSA-210993
Cell-Cell communication R-HSA-1500931
Metabolism of lipids R-HSA-556833
Developmental Biology R-HSA-1266738
Signaling by GPCR R-HSA-372790
PI3K/AKT Signaling in Cancer R-HSA-2219528
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by KIT in disease R-HSA-9669938
GPVI-mediated activation cascade R-HSA-114604
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
FLT3 Signaling R-HSA-9607240
RAF/MAP kinase cascade R-HSA-5673001
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
PI-3K cascade:FGFR2 R-HSA-5654695
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
FLT3 signaling in disease R-HSA-9682385
Signal Transduction R-HSA-162582
Signaling by EGFR R-HSA-177929
Signaling by NTRK2 (TRKB) R-HSA-9006115
Signaling by Nuclear Receptors R-HSA-9006931
TCR signaling R-HSA-202403
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by ERBB4 R-HSA-1236394
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by MET R-HSA-6806834
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI-3K cascade:FGFR3 R-HSA-5654710
GPCR downstream signalling R-HSA-388396
Immune System R-HSA-168256
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
CD28 co-stimulation R-HSA-389356
Metabolism R-HSA-1430728
Signaling by FLT3 fusion proteins R-HSA-9703465
Signaling by FGFR2 R-HSA-5654738
Extra-nuclear estrogen signaling R-HSA-9009391
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Regulation of signaling by CBL R-HSA-912631
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by Rho GTPases R-HSA-194315
Signaling by FGFR1 R-HSA-5654736
ESR-mediated signaling R-HSA-8939211
Signaling by FGFR3 R-HSA-5654741
PI Metabolism R-HSA-1483255
Disease R-HSA-1643685
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by EGFRvIII in Cancer R-HSA-5637812
Activated NTRK3 signals through PI3K R-HSA-9603381
Nervous system development R-HSA-9675108
Signaling by NTRKs R-HSA-166520
PI3K/AKT activation R-HSA-198203
Cytokine Signaling in Immune system R-HSA-1280215
Downstream signaling of activated FGFR4 R-HSA-5654716
Role of phospholipids in phagocytosis R-HSA-2029485
Intracellular signaling by second messengers R-HSA-9006925
Signaling by GPCR R-HSA-372790
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RHO GTPase cycle R-HSA-9012999
DAP12 interactions R-HSA-2172127
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by ALK fusions and activated point mutants R-HSA-9725370
PI-3K cascade:FGFR3 R-HSA-5654710
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by EGFRvIII in Cancer R-HSA-5637812
Downstream signaling of activated FGFR4 R-HSA-5654716
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by Insulin receptor R-HSA-74752
Signaling by EGFR R-HSA-177929
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ALK in cancer R-HSA-9700206
PI3K/AKT Signaling in Cancer R-HSA-2219528
GPCR downstream signalling R-HSA-388396
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-2 family signaling R-HSA-451927
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by FGFR3 in disease R-HSA-5655332
Signaling by ERBB2 KD Mutants R-HSA-9664565
Hemostasis R-HSA-109582
RAC2 GTPase cycle R-HSA-9013404
Disease R-HSA-1643685
CD28 dependent PI3K/Akt signaling R-HSA-389357
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
PI3K Cascade R-HSA-109704
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by FGFR2 R-HSA-5654738
Interleukin receptor SHC signaling R-HSA-912526
Signaling by VEGF R-HSA-194138
IRS-mediated signalling R-HSA-112399
RAF/MAP kinase cascade R-HSA-5673001
TCR signaling R-HSA-202403
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by Interleukins R-HSA-449147
Signaling by FGFR1 in disease R-HSA-5655302
Metabolism of lipids R-HSA-556833
Nervous system development R-HSA-9675108
RET signaling R-HSA-8853659
FLT3 Signaling R-HSA-9607240
Signaling by NTRK3 (TRKC) R-HSA-9034015
Nephrin family interactions R-HSA-373753
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by FGFR4 R-HSA-5654743
MET activates PI3K/AKT signaling R-HSA-8851907
Signaling by FGFR R-HSA-190236
Signaling by Erythropoietin R-HSA-9006335
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by FGFR3 R-HSA-5654741
Downstream signaling of activated FGFR1 R-HSA-5654687
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NTRKs R-HSA-166520
G alpha (q) signalling events R-HSA-416476
PI-3K cascade:FGFR4 R-HSA-5654720
PI3K/AKT activation R-HSA-198203
Negative regulation of the PI3K/AKT network R-HSA-199418
Regulation of signaling by CBL R-HSA-912631
Signaling by PDGF R-HSA-186797
Platelet activation, signaling and aggregation R-HSA-76002
PI3K events in ERBB4 signaling R-HSA-1250342
Signaling by FGFR1 R-HSA-5654736
Signaling by KIT in disease R-HSA-9669938
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by FGFR in disease R-HSA-1226099
FLT3 signaling in disease R-HSA-9682385
DAP12 signaling R-HSA-2424491
Signaling by ERBB4 R-HSA-1236394
Signaling by Rho GTPases R-HSA-194315
Signaling by ERBB2 ECD mutants R-HSA-9665348
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Costimulation by the CD28 family R-HSA-388841
ESR-mediated signaling R-HSA-8939211
PI-3K cascade:FGFR2 R-HSA-5654695
VEGFA-VEGFR2 Pathway R-HSA-4420097
Extra-nuclear estrogen signaling R-HSA-9009391
Immune System R-HSA-168256
Signaling by NTRK2 (TRKB) R-HSA-9006115
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by EGFR in Cancer R-HSA-1643713
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
IGF1R signaling cascade R-HSA-2428924
Activated NTRK3 signals through PI3K R-HSA-9603381
Signal Transduction R-HSA-162582
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Tie2 Signaling R-HSA-210993
Adaptive Immune System R-HSA-1280218
Signaling by FGFR4 in disease R-HSA-5655291
PI-3K cascade:FGFR1 R-HSA-5654689
Metabolism R-HSA-1430728
Downstream TCR signaling R-HSA-202424
MAPK family signaling cascades R-HSA-5683057
PI Metabolism R-HSA-1483255
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Axon guidance R-HSA-422475
Cell-Cell communication R-HSA-1500931
Signaling by NTRK1 (TRKA) R-HSA-187037
Innate Immune System R-HSA-168249
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Signaling by ERBB2 in Cancer R-HSA-1227990
Downstream signal transduction R-HSA-186763
GAB1 signalosome R-HSA-180292
Constitutive Signaling by EGFRvIII R-HSA-5637810
Insulin receptor signalling cascade R-HSA-74751
Signaling by FLT3 fusion proteins R-HSA-9703465
PI3K events in ERBB2 signaling R-HSA-1963642
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by MET R-HSA-6806834
Phospholipid metabolism R-HSA-1483257
Signaling by ALK R-HSA-201556
Signaling by PDGFR in disease R-HSA-9671555
Signaling by ERBB2 R-HSA-1227986
CD28 co-stimulation R-HSA-389356
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Cell surface interactions at the vascular wall R-HSA-202733
GPVI-mediated activation cascade R-HSA-114604
Signaling by SCF-KIT R-HSA-1433557
RAC1 GTPase cycle R-HSA-9013149
Signaling by FGFR3 in disease R-HSA-5655332
Negative regulation of the PI3K/AKT network R-HSA-199418
Nephrin family interactions R-HSA-373753
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by ALK R-HSA-201556
Signaling by FGFR2 in disease R-HSA-5655253
Innate Immune System R-HSA-168249
MET activates PI3K/AKT signaling R-HSA-8851907
RAC1 GTPase cycle R-HSA-9013149
Downstream signaling of activated FGFR4 R-HSA-5654716
FLT3 Signaling R-HSA-9607240
PI-3K cascade:FGFR2 R-HSA-5654695
IRS-related events triggered by IGF1R R-HSA-2428928
Interleukin-2 family signaling R-HSA-451927
Signaling by NTRKs R-HSA-166520
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by FLT3 fusion proteins R-HSA-9703465
Metabolism R-HSA-1430728
Phospholipid metabolism R-HSA-1483257
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by ERBB4 R-HSA-1236394
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by KIT in disease R-HSA-9669938
TCR signaling R-HSA-202403
Signaling by ERBB2 KD Mutants R-HSA-9664565
Tie2 Signaling R-HSA-210993
GPVI-mediated activation cascade R-HSA-114604
PI-3K cascade:FGFR4 R-HSA-5654720
Intracellular signaling by second messengers R-HSA-9006925
Developmental Biology R-HSA-1266738
GPCR downstream signalling R-HSA-388396
Costimulation by the CD28 family R-HSA-388841
RET signaling R-HSA-8853659
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Downstream signaling of activated FGFR1 R-HSA-5654687
Role of phospholipids in phagocytosis R-HSA-2029485
G alpha (q) signalling events R-HSA-416476
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
GAB1 signalosome R-HSA-180292
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Downstream TCR signaling R-HSA-202424
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR3 R-HSA-5654741
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Downstream signal transduction R-HSA-186763
PI Metabolism R-HSA-1483255
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by PDGF R-HSA-186797
PI3K events in ERBB2 signaling R-HSA-1963642
RHO GTPase cycle R-HSA-9012999
Regulation of signaling by CBL R-HSA-912631
Signaling by FGFR in disease R-HSA-1226099
Signaling by PDGFR in disease R-HSA-9671555
Hemostasis R-HSA-109582
Signaling by GPCR R-HSA-372790
Cell-Cell communication R-HSA-1500931
ESR-mediated signaling R-HSA-8939211
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by ERBB2 R-HSA-1227986
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Activated NTRK2 signals through PI3K R-HSA-9028335
Interleukin receptor SHC signaling R-HSA-912526
Signaling by MET R-HSA-6806834
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
PI3K/AKT Signaling in Cancer R-HSA-2219528
Synthesis of PIPs at the plasma membrane R-HSA-1660499
FLT3 signaling in disease R-HSA-9682385
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by EGFR R-HSA-177929
Signaling by FGFR1 R-HSA-5654736
Cytokine Signaling in Immune system R-HSA-1280215
Cell surface interactions at the vascular wall R-HSA-202733
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Interleukins R-HSA-449147
Signaling by ERBB2 in Cancer R-HSA-1227990
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DAP12 signaling R-HSA-2424491
Signaling by NTRK2 (TRKB) R-HSA-9006115
MAPK1/MAPK3 signaling R-HSA-5684996
Insulin receptor signalling cascade R-HSA-74751
Signaling by Insulin receptor R-HSA-74752
Signaling by ERBB2 ECD mutants R-HSA-9665348
Disease R-HSA-1643685
Adaptive Immune System R-HSA-1280218
Signaling by FGFR2 R-HSA-5654738
RAC2 GTPase cycle R-HSA-9013404
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by Rho GTPases R-HSA-194315
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of lipids R-HSA-556833
MAPK family signaling cascades R-HSA-5683057
PI3K/AKT activation R-HSA-198203
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by FGFR4 R-HSA-5654743
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
IRS-mediated signalling R-HSA-112399
PI3K events in ERBB4 signaling R-HSA-1250342
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by Erythropoietin R-HSA-9006335
Signaling by FGFR R-HSA-190236
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by EGFRvIII in Cancer R-HSA-5637812
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by NTRK3 (TRKC) R-HSA-9034015
PI3K Cascade R-HSA-109704
Signaling by ALK in cancer R-HSA-9700206
Immune System R-HSA-168256
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by VEGF R-HSA-194138
Platelet activation, signaling and aggregation R-HSA-76002
IGF1R signaling cascade R-HSA-2428924
PI-3K cascade:FGFR3 R-HSA-5654710
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
PIP3 activates AKT signaling R-HSA-1257604
DAP12 interactions R-HSA-2172127
Axon guidance R-HSA-422475
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by SCF-KIT R-HSA-1433557
CD28 co-stimulation R-HSA-389356
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Downstream signaling of activated FGFR3 R-HSA-5654708
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by FGFR in disease R-HSA-1226099
Role of phospholipids in phagocytosis R-HSA-2029485
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by NTRK3 (TRKC) R-HSA-9034015
PI-3K cascade:FGFR1 R-HSA-5654689
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by GPCR R-HSA-372790
Interleukin receptor SHC signaling R-HSA-912526
Signaling by FGFR3 in disease R-HSA-5655332
FGFR1 mutant receptor activation R-HSA-1839124
ESR-mediated signaling R-HSA-8939211
Signaling by Interleukins R-HSA-449147
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Insulin receptor signalling cascade R-HSA-74751
Phospholipid metabolism R-HSA-1483257
Signaling by Insulin receptor R-HSA-74752
RHO GTPase cycle R-HSA-9012999
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
MAPK family signaling cascades R-HSA-5683057
Signaling by KIT in disease R-HSA-9669938
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
DAP12 interactions R-HSA-2172127
FLT3 Signaling R-HSA-9607240
IGF1R signaling cascade R-HSA-2428924
Signaling by ALK in cancer R-HSA-9700206
Signaling by FLT3 fusion proteins R-HSA-9703465
Signaling by EGFR R-HSA-177929
Regulation of signaling by CBL R-HSA-912631
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
MAPK1/MAPK3 signaling R-HSA-5684996
Developmental Biology R-HSA-1266738
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Adaptive Immune System R-HSA-1280218
Interleukin-2 family signaling R-HSA-451927
Signaling by Erythropoietin R-HSA-9006335
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by NTRKs R-HSA-166520
G alpha (q) signalling events R-HSA-416476
Extra-nuclear estrogen signaling R-HSA-9009391
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Costimulation by the CD28 family R-HSA-388841
Signaling by ERBB2 in Cancer R-HSA-1227990
DAP12 signaling R-HSA-2424491
Signaling by SCF-KIT R-HSA-1433557
Axon guidance R-HSA-422475
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism of lipids R-HSA-556833
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by EGFR in Cancer R-HSA-1643713
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by FGFR2 R-HSA-5654738
Tie2 Signaling R-HSA-210993
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by EGFRvIII in Cancer R-HSA-5637812
Activated NTRK2 signals through PI3K R-HSA-9028335
Innate Immune System R-HSA-168249
Intracellular signaling by second messengers R-HSA-9006925
Activated NTRK3 signals through PI3K R-HSA-9603381
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by NTRK2 (TRKB) R-HSA-9006115
CD28 co-stimulation R-HSA-389356
GPCR downstream signalling R-HSA-388396
Nephrin family interactions R-HSA-373753
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by ERBB2 R-HSA-1227986
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by FGFR R-HSA-190236
GAB1 signalosome R-HSA-180292
PI-3K cascade:FGFR2 R-HSA-5654695
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Immune System R-HSA-168256
PI-3K cascade:FGFR4 R-HSA-5654720
Metabolism R-HSA-1430728
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by PDGFR in disease R-HSA-9671555
Hemostasis R-HSA-109582
Signaling by VEGF R-HSA-194138
RET signaling R-HSA-8853659
Signaling by FGFR2 in disease R-HSA-5655253
PI Metabolism R-HSA-1483255
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
PI3K events in ERBB4 signaling R-HSA-1250342
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PIP3 activates AKT signaling R-HSA-1257604
GPVI-mediated activation cascade R-HSA-114604
Signaling by FGFR3 R-HSA-5654741
Signaling by PDGF R-HSA-186797
VEGFA-VEGFR2 Pathway R-HSA-4420097
PI-3K cascade:FGFR3 R-HSA-5654710
CD28 dependent PI3K/Akt signaling R-HSA-389357
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
RAC2 GTPase cycle R-HSA-9013404
Signaling by FGFR1 R-HSA-5654736
FLT3 signaling in disease R-HSA-9682385
Signaling by ERBB4 R-HSA-1236394
RAC1 GTPase cycle R-HSA-9013149
PI3K/AKT activation R-HSA-198203
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by ERBB2 ECD mutants R-HSA-9665348
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MET activates PI3K/AKT signaling R-HSA-8851907
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by Rho GTPases R-HSA-194315
TCR signaling R-HSA-202403
Cell-Cell communication R-HSA-1500931
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by MET R-HSA-6806834
Signaling by NTRK1 (TRKA) R-HSA-187037
RAF/MAP kinase cascade R-HSA-5673001
Signaling by ALK R-HSA-201556
Signaling by FGFR4 R-HSA-5654743
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Downstream signal transduction R-HSA-186763
IRS-mediated signalling R-HSA-112399
Disease R-HSA-1643685
Downstream TCR signaling R-HSA-202424
Downstream signaling of activated FGFR3 R-HSA-5654708
Nervous system development R-HSA-9675108

Expression Atlas ENSG00000121879
LRG display in Ensembl gene LRG_310
NCBI gene (formerly Entrezgene) 5290
GeneCards 8975
HGNC Symbol HGNC:8975
MIM gene 171834
MIM morbid 619538
UniProtKB Gene Name P42336
WikiGene 5290
Gene: PARP1
Ensembl ID : ENSG00000143799
Description: poly(ADP-ribose) polymerase 1
Gene Synonyms: ADPRT,ARTD1,PARP,PARS,POLY-PARP,PPOL
10 APIs:
206 Possible Orthologues:

SUMOylation of DNA damage response and repair proteins R-HSA-3108214
DNA Damage Recognition in GG-NER R-HSA-5696394
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
vRNA Synthesis R-HSA-192814
Gene expression (Transcription) R-HSA-74160
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Disease R-HSA-1643685
Post-translational protein modification R-HSA-597592
Signaling by TGFB family members R-HSA-9006936
Nucleotide Excision Repair R-HSA-5696398
Influenza Infection R-HSA-168255
Formation of Incision Complex in GG-NER R-HSA-5696395
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Metabolism of proteins R-HSA-392499
Homology Directed Repair R-HSA-5693538
Infectious disease R-HSA-5663205
DNA Double-Strand Break Repair R-HSA-5693532
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Dual Incision in GG-NER R-HSA-5696400
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Influenza Viral RNA Transcription and Replication R-HSA-168273
SUMOylation R-HSA-2990846
DNA Repair R-HSA-73894
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
Resolution of Abasic Sites (AP sites) R-HSA-73933
Signaling by TGF-beta Receptor Complex R-HSA-170834
Generic Transcription Pathway R-HSA-212436
Base Excision Repair R-HSA-73884
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Base Excision Repair R-HSA-73884
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Dual Incision in GG-NER R-HSA-5696400
Disease R-HSA-1643685
DNA Double-Strand Break Repair R-HSA-5693532
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Signaling by TGF-beta Receptor Complex R-HSA-170834
DNA Repair R-HSA-73894
Formation of Incision Complex in GG-NER R-HSA-5696395
Homology Directed Repair R-HSA-5693538
Resolution of Abasic Sites (AP sites) R-HSA-73933
RNA Polymerase II Transcription R-HSA-73857
vRNA Synthesis R-HSA-192814
DNA Damage Recognition in GG-NER R-HSA-5696394
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Signaling by TGFB family members R-HSA-9006936
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Influenza Viral RNA Transcription and Replication R-HSA-168273
Nucleotide Excision Repair R-HSA-5696398
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
Post-translational protein modification R-HSA-597592
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Metabolism of proteins R-HSA-392499
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Influenza Infection R-HSA-168255
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
SUMOylation R-HSA-2990846
SUMOylation R-HSA-2990846
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Signal Transduction R-HSA-162582
Resolution of Abasic Sites (AP sites) R-HSA-73933
Infectious disease R-HSA-5663205
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Signaling by TGF-beta Receptor Complex R-HSA-170834
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Disease R-HSA-1643685
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
DNA Damage Recognition in GG-NER R-HSA-5696394
RNA Polymerase II Transcription R-HSA-73857
Signaling by TGFB family members R-HSA-9006936
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Base Excision Repair R-HSA-73884
Dual Incision in GG-NER R-HSA-5696400
DNA Double-Strand Break Repair R-HSA-5693532
DNA Repair R-HSA-73894
Formation of Incision Complex in GG-NER R-HSA-5696395
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Nucleotide Excision Repair R-HSA-5696398
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Influenza Viral RNA Transcription and Replication R-HSA-168273
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
vRNA Synthesis R-HSA-192814
Homology Directed Repair R-HSA-5693538
Influenza Infection R-HSA-168255
DNA Damage Recognition in GG-NER R-HSA-5696394
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Generic Transcription Pathway R-HSA-212436
Base Excision Repair R-HSA-73884
Resolution of Abasic Sites (AP sites) R-HSA-73933
RNA Polymerase II Transcription R-HSA-73857
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Signaling by TGFB family members R-HSA-9006936
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Signal Transduction R-HSA-162582
Nucleotide Excision Repair R-HSA-5696398
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Signaling by TGF-beta Receptor Complex R-HSA-170834
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
SUMOylation R-HSA-2990846
DNA Double-Strand Break Repair R-HSA-5693532
Homology Directed Repair R-HSA-5693538
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Influenza Viral RNA Transcription and Replication R-HSA-168273
Gene expression (Transcription) R-HSA-74160
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Dual Incision in GG-NER R-HSA-5696400
vRNA Synthesis R-HSA-192814
Influenza Infection R-HSA-168255
Formation of Incision Complex in GG-NER R-HSA-5696395
DNA Repair R-HSA-73894
vRNA Synthesis R-HSA-192814
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Base Excision Repair R-HSA-73884
Resolution of Abasic Sites (AP sites) R-HSA-73933
SUMOylation R-HSA-2990846
Metabolism of proteins R-HSA-392499
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
DNA Damage Recognition in GG-NER R-HSA-5696394
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Gene expression (Transcription) R-HSA-74160
Influenza Infection R-HSA-168255
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Homology Directed Repair R-HSA-5693538
DNA Double-Strand Break Repair R-HSA-5693532
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Influenza Viral RNA Transcription and Replication R-HSA-168273
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Generic Transcription Pathway R-HSA-212436
Nucleotide Excision Repair R-HSA-5696398
Formation of Incision Complex in GG-NER R-HSA-5696395
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by TGFB family members R-HSA-9006936
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Post-translational protein modification R-HSA-597592
DNA Repair R-HSA-73894
Dual Incision in GG-NER R-HSA-5696400
DNA Double-Strand Break Repair R-HSA-5693532
vRNA Synthesis R-HSA-192814
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Metabolism of proteins R-HSA-392499
Influenza Viral RNA Transcription and Replication R-HSA-168273
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Signaling by TGFB family members R-HSA-9006936
Signal Transduction R-HSA-162582
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Formation of Incision Complex in GG-NER R-HSA-5696395
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Homology Directed Repair R-HSA-5693538
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Influenza Infection R-HSA-168255
Dual Incision in GG-NER R-HSA-5696400
Nucleotide Excision Repair R-HSA-5696398
DNA Damage Recognition in GG-NER R-HSA-5696394
Generic Transcription Pathway R-HSA-212436
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
RNA Polymerase II Transcription R-HSA-73857
DNA Repair R-HSA-73894
Base Excision Repair R-HSA-73884
Resolution of Abasic Sites (AP sites) R-HSA-73933
Gene expression (Transcription) R-HSA-74160
SUMOylation R-HSA-2990846
Disease R-HSA-1643685
Signaling by TGF-beta Receptor Complex R-HSA-170834
SUMOylation R-HSA-2990846
Nucleotide Excision Repair R-HSA-5696398
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Signaling by TGF-beta Receptor Complex R-HSA-170834
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Base Excision Repair R-HSA-73884
Formation of Incision Complex in GG-NER R-HSA-5696395
Signal Transduction R-HSA-162582
Post-translational protein modification R-HSA-597592
DNA Damage Recognition in GG-NER R-HSA-5696394
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Gene expression (Transcription) R-HSA-74160
DNA Double-Strand Break Repair R-HSA-5693532
DNA Repair R-HSA-73894
Dual Incision in GG-NER R-HSA-5696400
Homology Directed Repair R-HSA-5693538
Influenza Infection R-HSA-168255
vRNA Synthesis R-HSA-192814
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
RNA Polymerase II Transcription R-HSA-73857
Resolution of Abasic Sites (AP sites) R-HSA-73933
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Generic Transcription Pathway R-HSA-212436
Signaling by TGFB family members R-HSA-9006936
Influenza Viral RNA Transcription and Replication R-HSA-168273
Metabolism of proteins R-HSA-392499
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
DNA Damage Recognition in GG-NER R-HSA-5696394
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Dual Incision in GG-NER R-HSA-5696400
DNA Double-Strand Break Repair R-HSA-5693532
vRNA Synthesis R-HSA-192814
Resolution of Abasic Sites (AP sites) R-HSA-73933
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Influenza Infection R-HSA-168255
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Generic Transcription Pathway R-HSA-212436
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Base Excision Repair R-HSA-73884
Signaling by TGFB family members R-HSA-9006936
Formation of Incision Complex in GG-NER R-HSA-5696395
Signal Transduction R-HSA-162582
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Nucleotide Excision Repair R-HSA-5696398
Signaling by TGF-beta Receptor Complex R-HSA-170834
Homology Directed Repair R-HSA-5693538
Disease R-HSA-1643685
Influenza Viral RNA Transcription and Replication R-HSA-168273
Gene expression (Transcription) R-HSA-74160
DNA Repair R-HSA-73894
SUMOylation R-HSA-2990846
SUMOylation R-HSA-2990846
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Infectious disease R-HSA-5663205
Base Excision Repair R-HSA-73884
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Post-translational protein modification R-HSA-597592
vRNA Synthesis R-HSA-192814
Homology Directed Repair R-HSA-5693538
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Gene expression (Transcription) R-HSA-74160
Dual Incision in GG-NER R-HSA-5696400
Resolution of Abasic Sites (AP sites) R-HSA-73933
Nucleotide Excision Repair R-HSA-5696398
Signaling by TGF-beta Receptor Complex R-HSA-170834
Influenza Infection R-HSA-168255
DNA Double-Strand Break Repair R-HSA-5693532
Signal Transduction R-HSA-162582
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Signaling by TGFB family members R-HSA-9006936
Metabolism of proteins R-HSA-392499
DNA Damage Recognition in GG-NER R-HSA-5696394
Formation of Incision Complex in GG-NER R-HSA-5696395
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Disease R-HSA-1643685
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
DNA Repair R-HSA-73894
Influenza Viral RNA Transcription and Replication R-HSA-168273
Signal Transduction R-HSA-162582
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Base Excision Repair R-HSA-73884
Influenza Infection R-HSA-168255
Signaling by TGF-beta Receptor Complex R-HSA-170834
RNA Polymerase II Transcription R-HSA-73857
Resolution of Abasic Sites (AP sites) R-HSA-73933
Influenza Viral RNA Transcription and Replication R-HSA-168273
DNA Damage Recognition in GG-NER R-HSA-5696394
Signaling by TGFB family members R-HSA-9006936
Disease R-HSA-1643685
Homology Directed Repair R-HSA-5693538
DNA Double-Strand Break Repair R-HSA-5693532
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Nucleotide Excision Repair R-HSA-5696398
Generic Transcription Pathway R-HSA-212436
DNA Repair R-HSA-73894
Dual Incision in GG-NER R-HSA-5696400
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
SUMOylation R-HSA-2990846
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Infectious disease R-HSA-5663205
Post-translational protein modification R-HSA-597592
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
vRNA Synthesis R-HSA-192814
Formation of Incision Complex in GG-NER R-HSA-5696395
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Infectious disease R-HSA-5663205
SUMOylation R-HSA-2990846
Base Excision Repair R-HSA-73884
Dual Incision in GG-NER R-HSA-5696400
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Formation of Incision Complex in GG-NER R-HSA-5696395
Homology Directed Repair R-HSA-5693538
Signal Transduction R-HSA-162582
Resolution of Abasic Sites (AP sites) R-HSA-73933
Gene expression (Transcription) R-HSA-74160
Influenza Viral RNA Transcription and Replication R-HSA-168273
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
DNA Repair R-HSA-73894
Signaling by TGFB family members R-HSA-9006936
Influenza Infection R-HSA-168255
RNA Polymerase II Transcription R-HSA-73857
vRNA Synthesis R-HSA-192814
Signaling by TGF-beta Receptor Complex R-HSA-170834
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
DNA Double-Strand Break Repair R-HSA-5693532
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
DNA Damage Recognition in GG-NER R-HSA-5696394
Generic Transcription Pathway R-HSA-212436
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Nucleotide Excision Repair R-HSA-5696398

Expression Atlas ENSG00000143799
NCBI gene (formerly Entrezgene) 142
GeneCards 270
HGNC Symbol HGNC:270
MIM gene 173870
UniProtKB Gene Name P09874
WikiGene 142
Gene: PDE7B
Ensembl ID : ENSG00000171408
Description: phosphodiesterase 7B
Gene Synonyms:
1 APIs:
174 Possible Orthologues:

Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790

Expression Atlas ENSG00000171408
NCBI gene (formerly Entrezgene) 27115
GeneCards 8792
HGNC Symbol HGNC:8792
MIM gene 604645
UniProtKB Gene Name Q9NP56
WikiGene 27115
Gene: PDGFRB
Ensembl ID : ENSG00000113721
Description: platelet derived growth factor receptor beta
Gene Synonyms: CD140B,JTK12,PDGFR,PDGFR1
40 APIs:
247 Possible Orthologues:

Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Downstream signal transduction R-HSA-186763
Signaling by PDGF R-HSA-186797
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAF/MAP kinase cascade R-HSA-5673001
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by PDGF R-HSA-186797
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Downstream signal transduction R-HSA-186763
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Downstream signal transduction R-HSA-186763
MAPK family signaling cascades R-HSA-5683057
Signaling by PDGF R-HSA-186797
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Negative regulation of the PI3K/AKT network R-HSA-199418
PIP3 activates AKT signaling R-HSA-1257604
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
MAPK1/MAPK3 signaling R-HSA-5684996
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGF R-HSA-186797
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signal transduction R-HSA-186763
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by PDGF R-HSA-186797
Downstream signal transduction R-HSA-186763
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
Downstream signal transduction R-HSA-186763
Disease R-HSA-1643685
Signaling by PDGF R-HSA-186797
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by PDGF R-HSA-186797
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Downstream signal transduction R-HSA-186763
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF/MAP kinase cascade R-HSA-5673001
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by PDGF R-HSA-186797
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Intracellular signaling by second messengers R-HSA-9006925
Downstream signal transduction R-HSA-186763
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Signaling by PDGF R-HSA-186797
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signal transduction R-HSA-186763
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RAF/MAP kinase cascade R-HSA-5673001
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK family signaling cascades R-HSA-5683057
Signaling by PDGF R-HSA-186797
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signal transduction R-HSA-186763
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604

Expression Atlas ENSG00000113721
NCBI gene (formerly Entrezgene) 5159
GeneCards 8804
HGNC Symbol HGNC:8804
MIM gene 173410
MIM morbid 616592
UniProtKB Gene Name P09619
WikiGene 5159