METOMINOSTROBIN

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Source Gaulton A, Kale N, van Westen GJ, Bellis LJ, Bento AP, Davies M, Hersey A, Papadatos G, Forster M, Wege P, Overington JP. A large-scale crop protection bioassay data set. Sci Data. 2015 Jul 7;2:150032. Read more ...

Structure

InChI Key HIIRDDUVRXCDBN-OBGWFSINSA-N
Smiles CNC(=O)\C(=N\OC)\c1ccccc1Oc2ccccc2
InChI
InChI=1S/C16H16N2O3/c1-17-16(19)15(18-20-2)13-10-6-7-11-14(13)21-12-8-4-3-5-9-12/h3-11H,1-2H3,(H,17,19)/b18-15+

Physicochemical Descriptors

Property Name Value
Molecular Formula C16H16N2O3
Molecular Weight 284.31
AlogP 2.59
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 5.0
Polar Surface Area 59.92
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 21.0
Assay Description Organism Bioactivity Reference
Fungicidal activity against Blumeria graminis infected compound pre-treated wheat plants assessed as disease preventive activity at 1.5 ppm measured after 1 or 2 weeks Blumeria graminis 65.0 %
Fungicidal activity against Blumeria graminis infected compound pre-treated wheat plants assessed as disease preventive activity at 3.1 ppm measured after 1 or 2 weeks Blumeria graminis 85.0 %
Fungicidal activity against Blumeria graminis infected compound pre-treated wheat plants assessed as disease preventive activity at 6.2 ppm measured after 1 or 2 weeks Blumeria graminis 95.0 %
Fungicidal activity against Blumeria graminis infected compound pre-treated wheat plants assessed as disease preventive activity at 500 ppm measured after 1 or 2 weeks Blumeria graminis 100.0 %
Fungicidal activity against Blumeria graminis infected compound pre-treated wheat plants assessed as disease preventive activity at 100 ppm measured after 1 or 2 weeks Blumeria graminis 100.0 %
Curative fungicidal activity against Botryotinia fuckeliana infected cucumber plant at 7.8 ppm by foliar application Botryotinia fuckeliana 30.0 %
Curative fungicidal activity against Botryotinia fuckeliana infected cucumber plant at 31.3 ppm by foliar application Botryotinia fuckeliana 40.0 %
Preventive fungicidal activity against Botryotinia fuckeliana infected cucumber plant at 7.8 ppm by foliar application Botryotinia fuckeliana 30.0 %
Preventive fungicidal activity against Botryotinia fuckeliana infected cucumber plant at 31.3 ppm by foliar application Botryotinia fuckeliana 55.0 %
Curative fungicidal activity against Podosphaera fuliginea infected cucumber plant at 7.8 ppm by foliar application Podosphaera fuliginea 70.0 %
Curative fungicidal activity against Podosphaera fuliginea infected cucumber plant at 31.3 ppm by foliar application Podosphaera fuliginea 97.0 %
Preventive fungicidal activity against Podosphaera fuliginea infected cucumber plant at 7.8 ppm by foliar application Podosphaera fuliginea 70.0 %
Preventive fungicidal activity against Podosphaera fuliginea infected cucumber plant at 31.3 ppm by foliar application Podosphaera fuliginea 100.0 %
Curative fungicidal activity against Pseudoperonospora cubensis infected cucumber leaves at 7.8 ppm after by foliar application method Pseudoperonospora cubensis 70.0 %
Curative fungicidal activity against Pseudoperonospora cubensis infected cucumber leaves at 31.3 ppm after by foliar application method Pseudoperonospora cubensis 97.0 %
Preventive fungicidal activity against Pseudoperonospora cubensis infected cucumber leaves at 31.3 ppm after by foliar application method Pseudoperonospora cubensis 60.0 %
Preventive fungicidal activity against Pseudoperonospora cubensis infected cucumber leaves at 7.8 ppm after by foliar application method Pseudoperonospora cubensis 40.0 %
Curative fungicidal activity against Podosphaera fuliginea infected cucumber leaves at 31.3 ppm after by foliar application method Podosphaera fuliginea 40.0 %
Curative fungicidal activity against Podosphaera fuliginea infected cucumber leaves at 7.8 ppm after by foliar application method Podosphaera fuliginea 0.0 %
Preventive fungicidal activity against Podosphaera fuliginea infected cucumber leaves at 31.3 ppm after by foliar application method Podosphaera fuliginea 100.0 %
Preventive fungicidal activity against Podosphaera fuliginea infected cucumber leaves at 7.8 ppm after by foliar application method Podosphaera fuliginea 70.0 %
Fungicidal activity against Pseudoperonospora cubensis assessed as cucumber downy mildew disease control at 125 ppm foliar application 24 hr after inoculation on upper surface of leaf by curative manner Pseudoperonospora cubensis 50.0 %
Fungicidal activity against Pseudoperonospora cubensis assessed as cucumber downy mildew disease control at 31.3 ppm foliar application 24 hr after inoculation on upper surface of leaf by curative manner Pseudoperonospora cubensis 50.0 %
Fungicidal activity against Pseudoperonospora cubensis assessed as cucumber downy mildew disease control at 7.8 ppm foliar application 24 hr after inoculation on upper surface of leaf by curative manner Pseudoperonospora cubensis 50.0 %
Fungicidal activity against Pseudoperonospora cubensis assessed as cucumber downy mildew disease control at 2 ppm foliar application 24 hr after inoculation on upper surface of leaf by curative manner Pseudoperonospora cubensis 50.0 %
Fungicidal activity against Botryotinia fuckeliana assessed as cucumber gray mold disease control at 125 ppm foliar application 24 hr after inoculation at 22 +/- 2 degC measured after 3 days by curative manner Botryotinia fuckeliana 50.0 %
Fungicidal activity against Botryotinia fuckeliana assessed as cucumber gray mold disease control at 31.3 ppm foliar application 24 hr after inoculation at 22 +/- 2 degC measured after 3 days by curative manner Botryotinia fuckeliana 50.0 %
Fungicidal activity against Botryotinia fuckeliana assessed as cucumber gray mold disease control at 7.8 ppm foliar application 24 hr after inoculation at 22 +/- 2 degC measured after 3 days by curative manner Botryotinia fuckeliana 50.0 %
Fungicidal activity against Botryotinia fuckeliana assessed as cucumber gray mold disease control at 2 ppm foliar application 24 hr after inoculation at 22 +/- 2 degC measured after 3 days by curative manner Botryotinia fuckeliana 50.0 %
Fungicidal activity against Podosphaera fuliginea assessed as cucumber powdery mildew control under greenhouse at 125 ppm foliar application 24 hr after inoculation on upper surface of leaf at 23 +/- 2 degC by curative manner Podosphaera fuliginea 50.0 %
Fungicidal activity against Podosphaera fuliginea assessed as cucumber powdery mildew control under greenhouse at 31.3 ppm foliar application 24 hr after inoculation on upper surface of leaf at 23 +/- 2 degC by curative manner Podosphaera fuliginea 50.0 %
Fungicidal activity against Podosphaera fuliginea assessed as cucumber powdery mildew control under greenhouse at 7.8 ppm foliar application 24 hr after inoculation on upper surface of leaf at 23 +/- 2 degC by curative manner Podosphaera fuliginea 50.0 %
Fungicidal activity against Podosphaera fuliginea assessed as cucumber powdery mildew control under greenhouse at 2 ppm foliar application 24 hr after inoculation on upper surface of leaf at 23 +/- 2 degC by curative manner Podosphaera fuliginea 50.0 %
Fungicidal activity against Magnaporthe oryzae assessed as rice blast disease control at 10 ppm submerged application measured after 7 days Magnaporthe oryzae 50.0 %
Fungicidal activity against Magnaporthe oryzae assessed as rice blast disease control at 2.5 ppm submerged application measured after 7 days Magnaporthe oryzae 50.0 %
Fungicidal activity against Magnaporthe oryzae assessed as rice blast disease control at 0.63 ppm submerged application measured after 7 days Magnaporthe oryzae 50.0 %
Fungicidal activity against Magnaporthe oryzae assessed as rice blast disease control at 0.16 ppm submerged application measured after 7 days Magnaporthe oryzae 50.0 %
Fungicidal activity against Pseudoperonospora cubensis assessed as cucumber downy mildew disease control at 125 ppm foliar application 24 hr before inoculation on upper surface of leaf by preventive manner Pseudoperonospora cubensis 100.0 %
Fungicidal activity against Pseudoperonospora cubensis assessed as cucumber downy mildew disease control at 31.3 ppm foliar application 24 hr before inoculation on upper surface of leaf by preventive manner Pseudoperonospora cubensis 100.0 %
Fungicidal activity against Pseudoperonospora cubensis assessed as cucumber downy mildew disease control at 7.8 ppm foliar application 24 hr before inoculation on upper surface of leaf by preventive manner Pseudoperonospora cubensis 30.0 %
Fungicidal activity against Botryotinia fuckeliana assessed as cucumber gray mold disease control at 125 ppm foliar application 24 hr before inoculation at 22 +/- 2 degC measured after 3 days by preventive manner Botryotinia fuckeliana 95.0 %
Fungicidal activity against Botryotinia fuckeliana assessed as cucumber gray mold disease control at 31.3 ppm foliar application 24 hr before inoculation at 22 +/- 2 degC measured after 3 days by preventive manner Botryotinia fuckeliana 92.0 %
Fungicidal activity against Botryotinia fuckeliana assessed as cucumber gray mold disease control at 7.8 ppm foliar application 24 hr before inoculation at 22 +/- 2 degC measured after 3 days by preventive manner Botryotinia fuckeliana 73.0 %
Fungicidal activity against Podosphaera fuliginea assessed as cucumber powdery mildew control under greenhouse at 125 ppm foliar application 24 hr before inoculation on upper surface of leaf at 23 +/- 2 degC by preventive manner Podosphaera fuliginea 100.0 %
Fungicidal activity against Podosphaera fuliginea assessed as cucumber powdery mildew control under greenhouse at 31.3 ppm foliar application 24 hr before inoculation on upper surface of leaf at 23 +/- 2 degC by preventive manner Podosphaera fuliginea 100.0 %
Fungicidal activity against Podosphaera fuliginea assessed as cucumber powdery mildew control under greenhouse at 7.8 ppm foliar application 24 hr before inoculation on upper surface of leaf at 23 +/- 2 degC by preventive manner Podosphaera fuliginea 70.0 %
Fungicidal activity against Thanatephorus cucumeris assessed as rice sheath blight disease control at 125 ppm foliar application for 24 hr before inoculation at 26 +- 2 measured after 5 days by preventive manner Thanatephorus cucumeris 70.0 %
Fungicidal activity against Thanatephorus cucumeris assessed as rice sheath blight disease control at 31.3 ppm foliar application for 24 hr before inoculation at 26 +- 2 measured after 5 days by preventive manner Thanatephorus cucumeris 70.0 %
Fungicidal activity against Thanatephorus cucumeris assessed as rice sheath blight disease control at 7.8 ppm foliar application for 24 hr before inoculation at 26 +- 2 measured after 5 days by preventive manner Thanatephorus cucumeris 50.0 %
Fungicidal activity against Magnaporthe oryzae assessed as rice blast disease control at 125 ppm foliar application for 24 hr before inoculation at 27 +/- 2 degC measured after 5 days by preventive manner Magnaporthe oryzae 97.0 %
Fungicidal activity against Magnaporthe oryzae assessed as rice blast disease control at 31.3 ppm foliar application for 24 hr before inoculation at 27 +/- 2 degC measured after 5 days by preventive manner Magnaporthe oryzae 90.0 %
Fungicidal activity against Magnaporthe oryzae assessed as rice blast disease control at 7.8 ppm foliar application for 24 hr before inoculation at 27 +/- 2 degC measured after 5 days by preventive manner Magnaporthe oryzae 30.0 %
Fungicidal activity against Magnaporthe oryzae assessed as rice blast disease control at 2 ppm foliar application for 24 hr before inoculation at 27 +/- 2 degC measured after 5 days by preventive manner Magnaporthe oryzae 70.0 %
Fungicidal activity against Cladosporium herbarum assessed as inhibition of mycelial growth by agar dilution method Cladosporium herbarum 4.5 ppm
Fungicidal activity against Magnaporthe oryzae assessed as inhibition of mycelial growth by agar dilution method Magnaporthe oryzae 5.6 ppm
Fungicidal activity against Colletotrichum lagenaria assessed as inhibition of mycelial growth by agar dilution method Colletotrichum lagenaria 4.7 ppm
Fungicidal activity against Fusarium oxysporum assessed as inhibition of mycelial growth by agar dilution method Fusarium oxysporum 6.2 ppm
Fungicidal activity against Alternaria alternata apple pathotype assessed as inhibition of mycelial growth by agar dilution method Alternaria alternata 20.8 ppm
Fungicidal activity against Botryotinia fuckeliana assessed as inhibition of mycelial growth by agar dilution method Botryotinia fuckeliana 1.1 ppm
Fungicidal activity against Athelia rolfsii assessed as inhibition of mycelial growth by agar dilution method Athelia rolfsii 2.5 ppm
Fungicidal activity against Glomerella cingulata assessed as inhibition of mycelial growth by agar dilution method Glomerella cingulata 7.2 ppm
Fungicidal activity against Sclerotinia sclerotiorum assessed as inhibition of mycelial growth by agar dilution method Sclerotinia sclerotiorum 2.0 ppm
Fungicidal activity against Pythium aphanidermatum assessed as inhibition of mycelial growth by agar dilution method Pythium aphanidermatum 2.8 ppm

Cross References

Resources Reference
ChEMBL CHEMBL2253170
PubChem 5483872
SureChEMBL SCHEMBL18652
ZINC ZINC05700325
CONTENTS