FENVALERATE

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Synonyms
Source Gaulton A, Kale N, van Westen GJ, Bellis LJ, Bento AP, Davies M, Hersey A, Papadatos G, Forster M, Wege P, Overington JP. A large-scale crop protection bioassay data set. Sci Data. 2015 Jul 7;2:150032. Read more ...

Structure

InChI Key NYPJDWWKZLNGGM-UHFFFAOYSA-N
Smiles CC(C)C(C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1)c3ccc(Cl)cc3
InChI
InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3

Physicochemical Descriptors

Property Name Value
Molecular Formula C25H22ClNO3
Molecular Weight 419.9
AlogP 6.56
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 0.0
Number of Rotational Bond 8.0
Polar Surface Area 59.32
Molecular species None
Aromatic Rings 3.0
Heavy Atoms 30.0
Assay Description Organism Bioactivity Reference
Insecticidal activity against Culex quinquefasciatus assessed as contact mortality at 0.025 mg/ml at 24 hr by standard immersion method relative to control Culex quinquefasciatus 88.0 %
Insecticidal activity against Culex quinquefasciatus assessed as contact mortality at 0.025 mg/ml at 12 hr by standard immersion method relative to control Culex quinquefasciatus 40.0 %
Insecticidal activity against Culex quinquefasciatus assessed as contact mortality at 0.025 mg/ml at 4 hr by standard immersion method relative to control Culex quinquefasciatus 18.0 %
Insecticidal activity against Culex quinquefasciatus assessed as contact mortality at 0.025 mg/ml at 1 hr by standard immersion method relative to control Culex quinquefasciatus 10.0 %
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta HB1 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 5.83
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta HN2 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 7.23
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta SD1 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 9.8
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta FJ1 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 9.01
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta FJ3 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 9.06
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta SD2 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 12.0
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta FJ2 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 12.9
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta HB2 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 28.5
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta HN1 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 64.9
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta GZ5 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 189.0
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta GZ4 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 347.0
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta AH2 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 415.0
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta GZ3 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 824.0
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta GZ2 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 1042.0
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta YN2 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 1313.0
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta YN3 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 1403.0
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta YN7 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 1537.0
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta AH3 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 1546.0
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta GZ1 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 1860.0
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta AH1 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 2054.0
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta YN6 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 4115.0
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta YN1 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 8412.0
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta YN5 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 8816.0
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta YN4 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 9231.0
Resistance factor, ratio of LD50 for sixth-instar larvae of Helicoverpa assulta YN8 to LD50 for sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l Helicoverpa assulta 17622.0
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 0.723 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 0.162 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta HB1 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 7.34 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta HB1 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 0.944 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta HN2 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 7.63 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta HN2 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 1.17 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta SD1 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 14.8 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta SD1 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 1.59 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta FJ1 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 5.67 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta FJ1 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 1.46 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta FJ3 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 3.39 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta FJ3 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 1.47 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta SD2 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 27.2 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta SD2 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 1.94 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta FJ2 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 4.91 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta FJ2 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 2.08 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta HB2 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 18.0 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta HB2 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 4.62 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta HN1 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 23.1 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta HN1 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 10.5 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta GZ4 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 133.0 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta GZ4 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 56.2 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta GZ5 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 74.2 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta GZ5 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 30.6 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta AH2 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 259.0 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta AH2 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 67.3 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta GZ3 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 725.0 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta GZ3 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 133.0 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta GZ2 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 558.0 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta GZ2 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 169.0 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta YN2 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 673.0 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta YN2 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 213.0 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta YN3 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 388.0 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta YN3 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 227.0 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta YN7 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 507.0 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta YN7 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 249.0 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta AH3 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 470.0 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta AH3 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 251.0 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta AH1 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 833.0 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta AH1 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 333.0 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta GZ1 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 1043.0 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta GZ1 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 301.0 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta YN6 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 1467.0 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta YN6 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 667.0 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta YN1 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 4059.0 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta YN1 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 1363.0 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta YN5 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 4567.0 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta YN5 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 1428.0 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta YN4 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 4847.0 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta YN4 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 1495.0 mg.kg-1
Insecticidal activity against sixth-instar larvae of Helicoverpa assulta YN8 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 9100.0 ug/g Insecticidal activity against sixth-instar larvae of Helicoverpa assulta YN8 at 1.8 to 183360 mg/l after 48 hr by chi-squared analysis Helicoverpa assulta 2855.0 mg.kg-1
Ratio of LD50 for Laodelphax striatella Ibaraki (small brown planthopper) to LD50 for susceptible Laodelphax striatella Laodelphax striatella 1.4
Insecticidal activity against Laodelphax striatella Ibaraki (small brown planthopper) assessed as mortality compound treated topically on dorsal side Laodelphax striatella 1.9 mg.kg-1
Insecticidal activity against Laodelphax striatella Kumamoto (small brown planthopper) assessed as mortality compound treated topically on dorsal side Laodelphax striatella None
Insecticidal activity against susceptible Laodelphax striatella (small brown planthopper) assessed as mortality compound treated topically on dorsal side Laodelphax striatella 1.4 mg.kg-1
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA assessed as insect mortality at 4 to 16 ug/larva after 48 hr (fenvalerate alone control = 29.1 to 50.0%) Helicoverpa armigera 40.7 %
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA assessed as insect mortality at 4 to 16 ug/larva after 48 hr (fenvalerate alone control = 29.1 to 50.0%) Helicoverpa armigera 38.8 %
Potency index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer to LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA and dsCyt-b5-4 dsRNA after 48 hr Helicoverpa armigera 3.2
Potency index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer to LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCyt-b5-4 dsRNA after 48 hr Helicoverpa armigera 3.1
Potency index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer to LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 after 48 hr Helicoverpa armigera 2.4
Potency index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer to LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA after 48 hr Helicoverpa armigera 2.0
Potency index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer to LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA and dsCyt-b5-4 dsRNA after 36 hr Helicoverpa armigera 3.0
Potency index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer to LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCyt-b5-4 dsRNA after 36 hr Helicoverpa armigera 2.6
Potency index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer to LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 after 36 hr Helicoverpa armigera 2.9
Potency index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer to LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA after 36 hr Helicoverpa armigera 1.6
Potency index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer to LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA and dsCyt-b5-4 dsRNA after 24 hr Helicoverpa armigera 3.5
Potency index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer to LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCyt-b5-4 dsRNA after 24 hr Helicoverpa armigera 2.4
Potency index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer to LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 after 24 hr Helicoverpa armigera 2.9
Potency index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer to LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA and dsCyt-b5-4 dsRNA after 12 hr Helicoverpa armigera 3.7
Potency index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer to LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCyt-b5-4 dsRNA after 12 hr Helicoverpa armigera 2.5
Potency index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer to LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 after 12 hr Helicoverpa armigera 2.8
Potency index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer to LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA after 12 hr Helicoverpa armigera 2.0
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA and dsCyt-b5-4 dsRNA assessed as compound level per larva causing mortality after 48 hr Helicoverpa armigera 6.7 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCyt-b5-4 dsRNA assessed as compound level per larva causing mortality after 48 hr Helicoverpa armigera 6.9 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA assessed as compound level per larva causing mortality after 48 hr Helicoverpa armigera 8.9 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA assessed as compound level per larva causing mortality after 48 hr Helicoverpa armigera 10.7 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer assessed as compound level per larva causing mortality after 48 hr Helicoverpa armigera 21.5 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae without dsRNA injection assessed as compound level per larva causing mortality after 48 hr Helicoverpa armigera 23.1 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA and dsCyt-b5-4 dsRNA assessed as compound level per larva causing mortality after 36 hr Helicoverpa armigera 8.6 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCyt-b5-4 dsRNA assessed as compound level per larva causing mortality after 36 hr Helicoverpa armigera 9.9 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA assessed as compound level per larva causing mortality after 36 hr Helicoverpa armigera 8.9 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA assessed as compound level per larva causing mortality after 36 hr Helicoverpa armigera 16.5 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer assessed as compound level per larva causing mortality after 36 hr Helicoverpa armigera 25.6 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae without dsRNA injection assessed as compound level per larva causing mortality after 36 hr Helicoverpa armigera 26.1 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA and dsCyt-b5-4 dsRNA assessed as compound level per larva causing mortality after 24 hr Helicoverpa armigera 10.2 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCyt-b5-4 dsRNA assessed as compound level per larva causing mortality after 24 hr Helicoverpa armigera 14.5 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA assessed as compound level per larva causing mortality after 24 hr Helicoverpa armigera 12.3 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA assessed as compound level per larva causing mortality after 24 hr Helicoverpa armigera 19.7 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer assessed as compound level per larva causing mortality after 24 hr Helicoverpa armigera 35.2 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae without dsRNA injection assessed as compound level per larva causing mortality after 24 hr Helicoverpa armigera 35.7 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA and dsCyt-b5-4 dsRNA assessed as compound level per larva causing mortality after 12 hr Helicoverpa armigera 12.6 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCyt-b5-4 dsRNA assessed as compound level per larva causing mortality after 12 hr Helicoverpa armigera 19.0 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA assessed as compound level per larva causing mortality after 12 hr Helicoverpa armigera 16.8 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA assessed as compound level per larva causing mortality after 12 hr Helicoverpa armigera 23.9 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer assessed as compound level per larva causing mortality after 12 hr Helicoverpa armigera 46.8 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae without dsRNA injection assessed as compound level per larva causing mortality after 12 hr Helicoverpa armigera 48.8 ug
Resistance index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae to LD50 for fenvalerate-susceptible Helicoverpa armigera third-instar larvae Helicoverpa armigera 164.0
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae assessed as compound level per larva causing mortality after 48 hr Helicoverpa armigera 16.13 ug
Insecticidal activity against fenvalerate-susceptible Helicoverpa armigera third-instar larvae assessed as compound level per larva causing mortality after 48 hr Helicoverpa armigera 0.0982 ug
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA and dsCyt-b5-4 dsRNA assessed as insect mortality at 4 to 16 ug/larva after 48 hr (fenvalerate alone control = 29.1 to 50.0%) Helicoverpa armigera 44.4 %
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCyt-b5-4 dsRNA assessed as insect mortality at 4 to 16 ug/larva after 48 hr (fenvalerate alone control = 29.1 to 50.0%) Helicoverpa armigera 50.0 %
Potency index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer to LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA after 24 hr Helicoverpa armigera 1.8

Cross References

Resources Reference
ChEMBL CHEMBL492491
PubChem 3347
SureChEMBL SCHEMBL26911
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