EcoDrugPlus


Keyword(s):	Human Metabolites
Molecule Category	Free-form
UNII	H7H9M0ICD7
EPA CompTox	DTXSID40146951

Keyword(s):

Human Metabolites

Molecule Category

Free-form

UNII

H7H9M0ICD7

EPA CompTox

DTXSID40146951


InChI Key	NHTMYQFUQFNSKL-UHFFFAOYSA-N
Smiles	Fc1cc(ccc1NC2=NCCC2)c3ccc(NC4=NCCC4)c(F)c3
InChI	InChI=1S/C20H20F2N4/c21-15-11-13(5-7-17(15)25-19-3-1-9-23-19)14-6-8-18(16(22)12-14)26-20-4-2-10-24-20/h5-8,11-12H,1-4,9-10H2,(H,23,25)(H,24,26)

InChI Key

NHTMYQFUQFNSKL-UHFFFAOYSA-N

Smiles

Fc1cc(ccc1NC2=NCCC2)c3ccc(NC4=NCCC4)c(F)c3

InChI

InChI=1S/C20H20F2N4/c21-15-11-13(5-7-17(15)25-19-3-1-9-23-19)14-6-8-18(16(22)12-14)26-20-4-2-10-24-20/h5-8,11-12H,1-4,9-10H2,(H,23,25)(H,24,26)

Property Name	Value
Molecular Formula	C20H20F2N4
Molecular Weight	354.17
AlogP	4.84
Hydrogen Bond Acceptor	4.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	3.0
Polar Surface Area	48.78
Heavy Atoms	26.0

Property Name

Value

Molecular Formula

C20H20F2N4

Molecular Weight

354.17

AlogP

4.84

Hydrogen Bond Acceptor

4.0

Hydrogen Bond Donor

2.0

Number of Rotational Bond

3.0

Polar Surface Area

48.78

Heavy Atoms

26.0

Resources	Reference
CAS NUMBER	105102-20-3
NORMAN SUSDAT
FDA SRS	H7H9M0ICD7

Resources

Reference

CAS NUMBER

105102-20-3

NORMAN SUSDAT

FDA SRS

H7H9M0ICD7

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, Volume 54, Issue D1, 6 January 2026, Pages D1397–D1404, https://doi.org/10.1093/nar/gkaf1251

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

LIROLDINE

Structure

Physicochemical Descriptors

Cross References