EcoDrugPlus


Synonyms	(2r,6r)-hnk hydrochloride (2r,6r)-hydroxynorketamine hydrochloride Hydroxynorketamine, (2r,6r)-, hydrochloride
Status
Molecule Category	Salt-form
UNII	A2F3JNU7UV

Synonyms

(2r,6r)-hnk hydrochloride

(2r,6r)-hydroxynorketamine hydrochloride

Hydroxynorketamine, (2r,6r)-, hydrochloride

Status

Molecule Category

Salt-form

UNII

A2F3JNU7UV


InChI Key	ZQJVHBJDLMIKJK-MHDYBILJSA-N
Smiles	Cl.N[C@@]1(c2ccccc2Cl)CCC[C@@H](O)C1=O
InChI	InChI=1S/C12H14ClNO2.ClH/c13-9-5-2-1-4-8(9)12(14)7-3-6-10(15)11(12)16;/h1-2,4-5,10,15H,3,6-7,14H2;1H/t10-,12-;/m1./s1

InChI Key

ZQJVHBJDLMIKJK-MHDYBILJSA-N

Smiles

Cl.N[C@@]1(c2ccccc2Cl)CCC[C@@H](O)C1=O

InChI

InChI=1S/C12H14ClNO2.ClH/c13-9-5-2-1-4-8(9)12(14)7-3-6-10(15)11(12)16;/h1-2,4-5,10,15H,3,6-7,14H2;1H/t10-,12-;/m1./s1

Property Name	Value
Molecular Formula	C12H15Cl2NO2
Molecular Weight	276.16
AlogP	1.61
Hydrogen Bond Acceptor	3.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	1.0
Polar Surface Area	63.32
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	16.0

Property Name

Value

Molecular Formula

C12H15Cl2NO2

Molecular Weight

276.16

AlogP

1.61

Hydrogen Bond Acceptor

3.0

Hydrogen Bond Donor

2.0

Number of Rotational Bond

1.0

Polar Surface Area

63.32

Molecular species

NEUTRAL

Aromatic Rings

1.0

Heavy Atoms

16.0

Resources	Reference
ChEMBL	CHEMBL4650353
FDA SRS	A2F3JNU7UV

Resources

Reference

ChEMBL

CHEMBL4650353

FDA SRS

A2F3JNU7UV

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

HYDROXYNORKETAMINE, (2R,6R)-, HYDROCHLORIDE

Structure

Physicochemical Descriptors

Cross References