EcoDrugPlus


Synonyms	Alimemazine BAYER-1219 Dl-trimeprazine Methylpromazine RP-6549 Temaril Trimeprazine
Status
Molecule Category	Free-form
UNII	76H78MJJ52
EPA CompTox	DTXSID9023708


InChI Key	ZZHLYYDVIOPZBE-UHFFFAOYSA-N
Smiles	CC(CN(C)C)CN1c2ccccc2Sc2ccccc21
InChI	InChI=1S/C18H22N2S/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)21-18-11-7-5-9-16(18)20/h4-11,14H,12-13H2,1-3H3

Property Name	Value
Molecular Formula	C18H22N2S
Molecular Weight	298.45
AlogP	4.49
Hydrogen Bond Acceptor	3.0
Number of Rotational Bond	4.0
Polar Surface Area	6.48
Molecular species	BASE
Aromatic Rings	2.0
Heavy Atoms	21.0

Resources	Reference
ChEBI	9725
ChEMBL	CHEMBL829
DrugBank	DB01246
DrugCentral	2749
FDA SRS	76H78MJJ52
Human Metabolome Database	HMDB0015376
Guide to Pharmacology	7237
KEGG	C07172
PharmGKB	PA164744009
SureChEMBL	SCHEMBL18993

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

METHYLPROMAZINE

Structure

Physicochemical Descriptors

Related Entries

Cross References