MELPHALAN FLUFENAMIDE HYDROCHLORIDE

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Synonyms
Status
Molecule Category Salt-form
UNII 3412470A0V

Structure

InChI Key ZCMWSKHHXLCVHI-VROPFNGYSA-N
Smiles CCOC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@@H](N)Cc1ccc(N(CCCl)CCCl)cc1.Cl
InChI
InChI=1S/C24H30Cl2FN3O3.ClH/c1-2-33-24(32)22(16-18-3-7-19(27)8-4-18)29-23(31)21(28)15-17-5-9-20(10-6-17)30(13-11-25)14-12-26;/h3-10,21-22H,2,11-16,28H2,1H3,(H,29,31);1H/t21-,22-;/m0./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C24H31Cl3FN3O3
Molecular Weight 534.89
AlogP 3.27
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 13.0
Polar Surface Area 84.66
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 33.0

Pharmacology

Mechanism of Action Action Reference
DNA cross-linking agent CROSS-LINKING AGENT FDA

Cross References

Resources Reference
ChEMBL CHEMBL4297403
FDA SRS 3412470A0V
PubChem 70675838
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