JNJ-26483327

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Search structure


Synonyms	JNJ 26483327 Jnj-26483327
Status
Molecule Category	Free-form
UNII	16720VER1H

Pharmacology

Mechanism of Action	Action	Reference
Epidermal growth factor receptor erbB1 inhibitor	INHIBITOR	PubMed DOI

Target Conservation


Protein: Epidermal growth factor receptor erbB1 Description: Epidermal growth factor receptor Organism : Homo sapiens P00533 ENSG00000146648












Protein: Receptor protein-tyrosine kinase erbB-2 Description: Receptor tyrosine-protein kinase erbB-2 Organism : Homo sapiens P04626 ENSG00000141736











Protein: Tyrosine-protein kinase LCK Description: Tyrosine-protein kinase Lck Organism : Homo sapiens P06239 ENSG00000182866









Protein: Tyrosine-protein kinase FYN Description: Tyrosine-protein kinase Fyn Organism : Homo sapiens P06241 ENSG00000010810











Protein: Tyrosine-protein kinase YES Description: Tyrosine-protein kinase Yes Organism : Homo sapiens P07947 ENSG00000176105












Protein: Tyrosine-protein kinase Lyn Description: Tyrosine-protein kinase Lyn Organism : Homo sapiens P07948 ENSG00000254087











Protein: Tyrosine-protein kinase SRC Description: Proto-oncogene tyrosine-protein kinase Src Organism : Homo sapiens P12931 ENSG00000197122











Protein: Vascular endothelial growth factor receptor 3 Description: Vascular endothelial growth factor receptor 3 Organism : Homo sapiens P35916 ENSG00000037280











Protein: Receptor protein-tyrosine kinase erbB-4 Description: Receptor tyrosine-protein kinase erbB-4 Organism : Homo sapiens Q15303 ENSG00000178568

Cross References

Resources	Reference
ChEMBL	CHEMBL3545133
FDA SRS	16720VER1H
PubChem	11952856

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025