EcoDrugPlus


Synonyms	Bempedoic acid ESP-55016 ETC-1002 ETC1002 Nexletol
Status
Molecule Category	Free-form
ATC	C10AX15
UNII	1EJ6Z6Q368


InChI Key	HYHMLYSLQUKXKP-UHFFFAOYSA-N
Smiles	CC(C)(CCCCCC(O)CCCCCC(C)(C)C(=O)O)C(=O)O
InChI	InChI=1S/C19H36O5/c1-18(2,16(21)22)13-9-5-7-11-15(20)12-8-6-10-14-19(3,4)17(23)24/h15,20H,5-14H2,1-4H3,(H,21,22)(H,23,24)

Property Name	Value
Molecular Formula	C19H36O5
Molecular Weight	344.49
AlogP	4.47
Hydrogen Bond Acceptor	3.0
Hydrogen Bond Donor	3.0
Number of Rotational Bond	14.0
Polar Surface Area	94.83
Molecular species	ACID
Aromatic Rings	0.0
Heavy Atoms	24.0

Mechanism of Action	Action	Reference
ATP-citrate synthase inhibitor	INHIBITOR	FDA

Resources	Reference
ChEBI	149601
ChEMBL	CHEMBL3545313
DrugBank	DB11936
DrugCentral	5382
FDA SRS	1EJ6Z6Q368
Guide to Pharmacology	8321
PubChem	10472693
SureChEMBL	SCHEMBL185768
ZINC	ZINC000003948738

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

BEMPEDOIC ACID

Structure

Physicochemical Descriptors

Pharmacology

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