Trade Names | |
Synonyms | |
Status | |
Molecule Category | Free-form |
ATC | M04AB01 |
UNII | PO572Z7917 |
EPA CompTox | DTXSID9021188 |
InChI Key | DBABZHXKTCFAPX-UHFFFAOYSA-N | |
---|---|---|
Smiles | ||
InChI |
|
Property Name | Value | |
---|---|---|
Molecular Formula | C13H19NO4S | |
Molecular Weight | 285.36 | |
AlogP | 2.2 | |
Hydrogen Bond Acceptor | 3.0 | |
Hydrogen Bond Donor | 1.0 | |
Number of Rotational Bond | 7.0 | |
Polar Surface Area | 74.68 | |
Molecular species | ACID | |
Aromatic Rings | 1.0 | |
Heavy Atoms | 19.0 |
Mechanism of Action | Action | Reference | |
---|---|---|---|
Solute carrier family 22 member 11 inhibitor | INHIBITOR | PubMed PubMed PubMed PubMed Wikipedia |
Protein: Solute carrier family 22 member 6 Description: Solute carrier family 22 member 6 Organism : Homo sapiens Q4U2R8 ENSG00000197901 |
||||
Protein: Solute carrier family 22 member 8 Description: Organic anion transporter 3 Organism : Homo sapiens Q8TCC7 ENSG00000149452 |
||||
Protein: Solute carrier family 22 member 11 Description: Solute carrier family 22 member 11 Organism : Homo sapiens Q9NSA0 ENSG00000168065 |
||||
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | ||
---|---|---|---|---|---|---|---|
Enzyme
Lyase
|
- | - | - | 1245-1245 | - | ||
Enzyme
Transferase
|
- | - | - | 96000 | - | ||
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 22-89 | ||
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC22 family of organic cation and anion transporters
|
- | 15000-86390 | - | 6310-6400 | 30-36 |
Resources | Reference | |
---|---|---|
ChEBI | 8426 | |
ChEMBL | CHEMBL897 | |
DrugBank | DB01032 | |
DrugCentral | 2268 | |
FDA SRS | PO572Z7917 | |
Human Metabolome Database | HMDB0015166 | |
Guide to Pharmacology | 4357 | |
KEGG | C07372 | |
PharmGKB | PA451106 | |
PubChem | 4911 | |
SureChEMBL | SCHEMBL3663 | |
ZINC | ZINC000000001982 |