Gene: PDE7A
Ensembl ID : ENSG00000205268
Description: phosphodiesterase 7A
Gene Synonyms: HCP1
1 APIs:
240 Possible Orthologues:

GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555

Expression Atlas ENSG00000205268
NCBI gene (formerly Entrezgene) 5150
GeneCards 8791
HGNC Symbol HGNC:8791
MIM gene 171885
UniProtKB Gene Name Q13946
WikiGene 5150
Gene: NPC1L1
Ensembl ID : ENSG00000015520
Description: NPC1 like intracellular cholesterol transporter 1
Gene Synonyms: SLC65A2
1 APIs:
190 Possible Orthologues:

Digestion and absorption R-HSA-8963743
Intestinal lipid absorption R-HSA-8963678
Intestinal absorption R-HSA-8963676
Intestinal lipid absorption R-HSA-8963678
Digestion and absorption R-HSA-8963743
Intestinal absorption R-HSA-8963676
Digestion and absorption R-HSA-8963743
Intestinal absorption R-HSA-8963676
Intestinal lipid absorption R-HSA-8963678
Intestinal lipid absorption R-HSA-8963678
Intestinal absorption R-HSA-8963676
Digestion and absorption R-HSA-8963743
Intestinal lipid absorption R-HSA-8963678
Digestion and absorption R-HSA-8963743
Intestinal absorption R-HSA-8963676
Intestinal lipid absorption R-HSA-8963678
Digestion and absorption R-HSA-8963743
Intestinal absorption R-HSA-8963676
Intestinal lipid absorption R-HSA-8963678
Intestinal absorption R-HSA-8963676
Digestion and absorption R-HSA-8963743
Intestinal lipid absorption R-HSA-8963678
Digestion and absorption R-HSA-8963743
Intestinal absorption R-HSA-8963676
Intestinal absorption R-HSA-8963676
Digestion and absorption R-HSA-8963743
Intestinal lipid absorption R-HSA-8963678
Digestion and absorption R-HSA-8963743
Intestinal absorption R-HSA-8963676
Intestinal lipid absorption R-HSA-8963678

Expression Atlas ENSG00000015520
NCBI gene (formerly Entrezgene) 29881
GeneCards 7898
HGNC Symbol HGNC:7898
MIM gene 608010
MIM morbid 617966
UniProtKB Gene Name Q9UHC9
WikiGene 29881
Gene: PSMC4
Ensembl ID : ENSG00000013275
Description: proteasome 26S subunit, ATPase 4
Gene Synonyms: MGC13687,MGC23214,MGC8570,MIP224,RPT3,S6,TBP-7,TBP7
5 APIs:
199 Possible Orthologues:

Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
Beta-catenin independent WNT signaling R-HSA-3858494
Cell Cycle, Mitotic R-HSA-69278
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX3 R-HSA-8878159
Vpu mediated degradation of CD4 R-HSA-180534
Switching of origins to a post-replicative state R-HSA-69052
Negative regulation of NOTCH4 signaling R-HSA-9604323
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing-Cross presentation R-HSA-1236975
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
RAF/MAP kinase cascade R-HSA-5673001
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Synthesis of DNA R-HSA-69239
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Transition R-HSA-69275
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI1 by the proteasome R-HSA-5610780
Orc1 removal from chromatin R-HSA-68949
ABC transporter disorders R-HSA-5619084
Signaling by WNT R-HSA-195721
Host Interactions of HIV factors R-HSA-162909
Generic Transcription Pathway R-HSA-212436
Ub-specific processing proteases R-HSA-5689880
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of polyamines R-HSA-351202
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
Hh mutants abrogate ligand secretion R-HSA-5387390
Interleukin-1 signaling R-HSA-9020702
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by ROBO receptors R-HSA-376176
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of RUNX2 expression and activity R-HSA-8939902
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Transport of small molecules R-HSA-382551
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of Apoptosis R-HSA-169911
PTEN Regulation R-HSA-6807070
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Apoptosis R-HSA-109581
Degradation of GLI2 by the proteasome R-HSA-5610783
HIV Infection R-HSA-162906
p53-Independent DNA Damage Response R-HSA-69610
G2/M Checkpoints R-HSA-69481
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
Cellular response to chemical stress R-HSA-9711123
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular responses to stress R-HSA-2262752
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PIP3 activates AKT signaling R-HSA-1257604
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of RNA R-HSA-8953854
Innate Immune System R-HSA-168249
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Replication Pre-Initiation R-HSA-69002
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Replication R-HSA-69306
Assembly of the pre-replicative complex R-HSA-68867
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Stabilization of p53 R-HSA-69541
MAPK1/MAPK3 signaling R-HSA-5684996
PCP/CE pathway R-HSA-4086400
Signal Transduction R-HSA-162582
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Nervous system development R-HSA-9675108
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Deubiquitination R-HSA-5688426
Signaling by NOTCH R-HSA-157118
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'on' state R-HSA-5632684
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
S Phase R-HSA-69242
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Separation of Sister Chromatids R-HSA-2467813
Nuclear events mediated by NFE2L2 R-HSA-9759194
Post-translational protein modification R-HSA-597592
Degradation of DVL R-HSA-4641258
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
Disorders of transmembrane transporters R-HSA-5619115
Hedgehog 'off' state R-HSA-5610787
Cell Cycle Checkpoints R-HSA-69620
Cellular response to hypoxia R-HSA-1234174
UCH proteinases R-HSA-5689603
Programmed Cell Death R-HSA-5357801
Cellular responses to stimuli R-HSA-8953897
Cytokine Signaling in Immune system R-HSA-1280215
Hh mutants are degraded by ERAD R-HSA-5362768
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX1 R-HSA-8878171
Axon guidance R-HSA-422475
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
FCERI mediated NF-kB activation R-HSA-2871837
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G1 phase and G1/S transition R-HSA-453279
Interleukin-1 family signaling R-HSA-446652
Signaling by Hedgehog R-HSA-5358351
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
KEAP1-NFE2L2 pathway R-HSA-9755511
Cyclin E associated events during G1/S transition R-HSA-69202
Neddylation R-HSA-8951664
Gene expression (Transcription) R-HSA-74160
Downstream TCR signaling R-HSA-202424
Activation of NF-kappaB in B cells R-HSA-1169091
RNA Polymerase II Transcription R-HSA-73857
ER-Phagosome pathway R-HSA-1236974
Mitotic Anaphase R-HSA-68882
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional regulation by RUNX1 R-HSA-8878171
Stabilization of p53 R-HSA-69541
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog 'off' state R-HSA-5610787
RAF/MAP kinase cascade R-HSA-5673001
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism of amino acids and derivatives R-HSA-71291
Interleukin-1 family signaling R-HSA-446652
Axon guidance R-HSA-422475
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular responses to stimuli R-HSA-8953897
Separation of Sister Chromatids R-HSA-2467813
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic Anaphase R-HSA-68882
Switching of origins to a post-replicative state R-HSA-69052
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic Metaphase and Anaphase R-HSA-2555396
RNA Polymerase II Transcription R-HSA-73857
Degradation of beta-catenin by the destruction complex R-HSA-195253
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RUNX2 expression and activity R-HSA-8939902
Disorders of transmembrane transporters R-HSA-5619115
PTEN Regulation R-HSA-6807070
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by NOTCH R-HSA-157118
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Orc1 removal from chromatin R-HSA-68949
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
Neddylation R-HSA-8951664
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Innate Immune System R-HSA-168249
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'on' state R-HSA-5632684
TCF dependent signaling in response to WNT R-HSA-201681
Cellular response to hypoxia R-HSA-1234174
G1/S Transition R-HSA-69206
Signaling by Hedgehog R-HSA-5358351
Developmental Biology R-HSA-1266738
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCR signaling R-HSA-202403
S Phase R-HSA-69242
Defective CFTR causes cystic fibrosis R-HSA-5678895
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Gene expression (Transcription) R-HSA-74160
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
Activation of NF-kappaB in B cells R-HSA-1169091
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Generic Transcription Pathway R-HSA-212436
Antigen processing-Cross presentation R-HSA-1236975
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH4 R-HSA-9013694
Synthesis of DNA R-HSA-69239
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mitotic cell cycle R-HSA-453276
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
ER-Phagosome pathway R-HSA-1236974
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of polyamines R-HSA-351202
Interleukin-1 signaling R-HSA-9020702
Beta-catenin independent WNT signaling R-HSA-3858494
Assembly of the pre-replicative complex R-HSA-68867
Degradation of DVL R-HSA-4641258
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin E associated events during G1/S transition R-HSA-69202
Transport of small molecules R-HSA-382551
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G2/M Transition R-HSA-69275
Deubiquitination R-HSA-5688426
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of AXIN R-HSA-4641257
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ABC transporter disorders R-HSA-5619084
Adaptive Immune System R-HSA-1280218
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
DNA Replication R-HSA-69306
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PCP/CE pathway R-HSA-4086400
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
HIV Infection R-HSA-162906
UCH proteinases R-HSA-5689603
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI2 by the proteasome R-HSA-5610783
Downstream TCR signaling R-HSA-202424
G1/S DNA Damage Checkpoints R-HSA-69615
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular response to chemical stress R-HSA-9711123
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
Cell Cycle Checkpoints R-HSA-69620
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of RAS by GAPs R-HSA-5658442
Post-translational protein modification R-HSA-597592
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by WNT R-HSA-195721
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Programmed Cell Death R-HSA-5357801
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC-family proteins mediated transport R-HSA-382556
Transcriptional regulation by RUNX3 R-HSA-8878159
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of Apoptosis R-HSA-169911
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
M Phase R-HSA-68886
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ROBO receptors R-HSA-376176
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Apoptosis R-HSA-109581
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
Neddylation R-HSA-8951664
Infectious disease R-HSA-5663205
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog 'off' state R-HSA-5610787
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of RNA R-HSA-8953854
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX2 R-HSA-8878166
Nuclear events mediated by NFE2L2 R-HSA-9759194
Downstream TCR signaling R-HSA-202424
DNA Replication Pre-Initiation R-HSA-69002
Degradation of GLI1 by the proteasome R-HSA-5610780
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Beta-catenin independent WNT signaling R-HSA-3858494
Class I MHC mediated antigen processing & presentation R-HSA-983169
Apoptosis R-HSA-109581
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of amino acids and derivatives R-HSA-71291
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular responses to stimuli R-HSA-8953897
Antigen processing-Cross presentation R-HSA-1236975
Regulation of PTEN stability and activity R-HSA-8948751
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G2/M Checkpoints R-HSA-69481
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
UCH proteinases R-HSA-5689603
Cellular response to hypoxia R-HSA-1234174
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism of polyamines R-HSA-351202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
MAPK6/MAPK4 signaling R-HSA-5687128
Gene expression (Transcription) R-HSA-74160
TCR signaling R-HSA-202403
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular responses to stress R-HSA-2262752
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of AXIN R-HSA-4641257
Degradation of GLI2 by the proteasome R-HSA-5610783
PCP/CE pathway R-HSA-4086400
MAPK1/MAPK3 signaling R-HSA-5684996
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Immune System R-HSA-168256
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH4 R-HSA-9013694
ABC-family proteins mediated transport R-HSA-382556
Degradation of DVL R-HSA-4641258
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular response to chemical stress R-HSA-9711123
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S Transition R-HSA-69206
Regulation of RAS by GAPs R-HSA-5658442
Signaling by WNT R-HSA-195721
Signaling by NOTCH R-HSA-157118
Cell Cycle Checkpoints R-HSA-69620
Separation of Sister Chromatids R-HSA-2467813
Vpu mediated degradation of CD4 R-HSA-180534
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog ligand biogenesis R-HSA-5358346
Signal Transduction R-HSA-162582
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 signaling R-HSA-9020702
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent DNA Damage Response R-HSA-69610
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ABC transporter disorders R-HSA-5619084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic G2-G2/M phases R-HSA-453274
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nervous system development R-HSA-9675108
Hedgehog 'on' state R-HSA-5632684
Signaling by Interleukins R-HSA-449147
C-type lectin receptors (CLRs) R-HSA-5621481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Interleukin-1 family signaling R-HSA-446652
Transport of small molecules R-HSA-382551
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
Regulation of mitotic cell cycle R-HSA-453276
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle, Mitotic R-HSA-69278
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication R-HSA-69306
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disorders of transmembrane transporters R-HSA-5619115
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism R-HSA-1430728
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
PTEN Regulation R-HSA-6807070
HIV Infection R-HSA-162906
Deubiquitination R-HSA-5688426
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G2/M Transition R-HSA-69275
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by Hedgehog R-HSA-5358351
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle R-HSA-1640170
Regulation of RUNX2 expression and activity R-HSA-8939902
Hh mutants are degraded by ERAD R-HSA-5362768
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of beta-catenin by the destruction complex R-HSA-195253
Developmental Biology R-HSA-1266738
Hh mutants abrogate ligand secretion R-HSA-5387390
Host Interactions of HIV factors R-HSA-162909
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Vif-mediated degradation of APOBEC3G R-HSA-180585
MAPK family signaling cascades R-HSA-5683057
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G2/M Transition R-HSA-69275
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Antigen processing-Cross presentation R-HSA-1236975
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transport of small molecules R-HSA-382551
G2/M Checkpoints R-HSA-69481
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PTEN Regulation R-HSA-6807070
Metabolism of polyamines R-HSA-351202
MAPK1/MAPK3 signaling R-HSA-5684996
Infectious disease R-HSA-5663205
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of GLI1 by the proteasome R-HSA-5610780
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of Apoptosis R-HSA-169911
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Stabilization of p53 R-HSA-69541
Neddylation R-HSA-8951664
CLEC7A (Dectin-1) signaling R-HSA-5607764
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ER-Phagosome pathway R-HSA-1236974
Signaling by ROBO receptors R-HSA-376176
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of RNA R-HSA-8953854
Signaling by Interleukins R-HSA-449147
Signaling by NOTCH R-HSA-157118
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of DVL R-HSA-4641258
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to hypoxia R-HSA-1234174
ABC-family proteins mediated transport R-HSA-382556
Programmed Cell Death R-HSA-5357801
PIP3 activates AKT signaling R-HSA-1257604
DNA Replication Pre-Initiation R-HSA-69002
Signaling by Hedgehog R-HSA-5358351
MAPK family signaling cascades R-HSA-5683057
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by WNT R-HSA-195721
Signaling by NOTCH4 R-HSA-9013694
HIV Infection R-HSA-162906
Disorders of transmembrane transporters R-HSA-5619115
Vpu mediated degradation of CD4 R-HSA-180534
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'on' state R-HSA-5632684
Deubiquitination R-HSA-5688426
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G2-G2/M phases R-HSA-453274
Cellular response to chemical stress R-HSA-9711123
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Adaptive Immune System R-HSA-1280218
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX1 R-HSA-8878171
Synthesis of DNA R-HSA-69239
Cellular responses to stimuli R-HSA-8953897
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stress R-HSA-2262752
Metabolism R-HSA-1430728
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of amino acids and derivatives R-HSA-71291
Ub-specific processing proteases R-HSA-5689880
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic G1 phase and G1/S transition R-HSA-453279
Post-translational protein modification R-HSA-597592
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disease R-HSA-1643685
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
Cyclin E associated events during G1/S transition R-HSA-69202
Signal Transduction R-HSA-162582
Interleukin-1 family signaling R-HSA-446652
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RNA Polymerase II Transcription R-HSA-73857
ABC transporter disorders R-HSA-5619084
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S Transition R-HSA-69206
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX2 R-HSA-8878166
Negative regulation of NOTCH4 signaling R-HSA-9604323
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Intracellular signaling by second messengers R-HSA-9006925
Host Interactions of HIV factors R-HSA-162909
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
C-type lectin receptors (CLRs) R-HSA-5621481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of AXIN R-HSA-4641257
Innate Immune System R-HSA-168249
G1/S DNA Damage Checkpoints R-HSA-69615
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Immune System R-HSA-168256
DNA Replication R-HSA-69306
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Hedgehog 'off' state R-HSA-5610787
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of mitotic cell cycle R-HSA-453276
p53-Dependent G1 DNA Damage Response R-HSA-69563
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic Metaphase and Anaphase R-HSA-2555396
Axon guidance R-HSA-422475
Regulation of RAS by GAPs R-HSA-5658442
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 signaling R-HSA-9020702
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
FCERI mediated NF-kB activation R-HSA-2871837
Assembly of the pre-replicative complex R-HSA-68867
RAF/MAP kinase cascade R-HSA-5673001
M Phase R-HSA-68886
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cell Cycle Checkpoints R-HSA-69620
Regulation of PTEN stability and activity R-HSA-8948751
UCH proteinases R-HSA-5689603
Cell Cycle R-HSA-1640170
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disease R-HSA-1643685
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Downstream TCR signaling R-HSA-202424
UCH proteinases R-HSA-5689603
Cell Cycle Checkpoints R-HSA-69620
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by the B Cell Receptor (BCR) R-HSA-983705
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Independent DNA Damage Response R-HSA-69610
Switching of origins to a post-replicative state R-HSA-69052
G2/M Checkpoints R-HSA-69481
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of GLI1 by the proteasome R-HSA-5610780
Host Interactions of HIV factors R-HSA-162909
Assembly of the pre-replicative complex R-HSA-68867
Developmental Biology R-HSA-1266738
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
G1/S Transition R-HSA-69206
Innate Immune System R-HSA-168249
Stabilization of p53 R-HSA-69541
RAF/MAP kinase cascade R-HSA-5673001
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX1 R-HSA-8878171
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Defective CFTR causes cystic fibrosis R-HSA-5678895
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
ER-Phagosome pathway R-HSA-1236974
Degradation of AXIN R-HSA-4641257
Mitotic Anaphase R-HSA-68882
ABC-family proteins mediated transport R-HSA-382556
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
HIV Infection R-HSA-162906
Signaling by Interleukins R-HSA-449147
Separation of Sister Chromatids R-HSA-2467813
Cytokine Signaling in Immune system R-HSA-1280215
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular response to chemical stress R-HSA-9711123
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Immune System R-HSA-168256
Transport of small molecules R-HSA-382551
DNA Replication R-HSA-69306
Intracellular signaling by second messengers R-HSA-9006925
Mitotic G2-G2/M phases R-HSA-453274
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of Apoptosis R-HSA-169911
Degradation of GLI2 by the proteasome R-HSA-5610783
TCF dependent signaling in response to WNT R-HSA-201681
Gene expression (Transcription) R-HSA-74160
G1/S DNA Damage Checkpoints R-HSA-69615
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Neddylation R-HSA-8951664
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Signaling by Hedgehog R-HSA-5358351
Signaling by WNT R-HSA-195721
CLEC7A (Dectin-1) signaling R-HSA-5607764
Deubiquitination R-HSA-5688426
Cyclin E associated events during G1/S transition R-HSA-69202
S Phase R-HSA-69242
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Vif-mediated degradation of APOBEC3G R-HSA-180585
MAPK1/MAPK3 signaling R-HSA-5684996
Ub-specific processing proteases R-HSA-5689880
Hh mutants are degraded by ERAD R-HSA-5362768
Cell Cycle R-HSA-1640170
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Post-translational protein modification R-HSA-597592
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Class I MHC mediated antigen processing & presentation R-HSA-983169
PCP/CE pathway R-HSA-4086400
Orc1 removal from chromatin R-HSA-68949
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
ABC transporter disorders R-HSA-5619084
Metabolism of proteins R-HSA-392499
M Phase R-HSA-68886
PTEN Regulation R-HSA-6807070
Interleukin-1 signaling R-HSA-9020702
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular responses to stimuli R-HSA-8953897
Regulation of PTEN stability and activity R-HSA-8948751
C-type lectin receptors (CLRs) R-HSA-5621481
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activation of NF-kappaB in B cells R-HSA-1169091
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of polyamines R-HSA-351202
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RNA Polymerase II Transcription R-HSA-73857
Hedgehog 'off' state R-HSA-5610787
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Signaling by ROBO receptors R-HSA-376176
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH4 R-HSA-9013694
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle, Mitotic R-HSA-69278
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative regulation of NOTCH4 signaling R-HSA-9604323
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX3 R-HSA-8878159
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
Programmed Cell Death R-HSA-5357801
Disorders of transmembrane transporters R-HSA-5619115
Synthesis of DNA R-HSA-69239
G2/M Transition R-HSA-69275
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of DVL R-HSA-4641258
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism R-HSA-1430728
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Disorders of transmembrane transporters R-HSA-5619115
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism R-HSA-1430728
TCF dependent signaling in response to WNT R-HSA-201681
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular response to hypoxia R-HSA-1234174
PTEN Regulation R-HSA-6807070
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX2 R-HSA-8878166
Innate Immune System R-HSA-168249
Downstream TCR signaling R-HSA-202424
Antigen processing-Cross presentation R-HSA-1236975
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic G2-G2/M phases R-HSA-453274
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of DVL R-HSA-4641258
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
ABC-family proteins mediated transport R-HSA-382556
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Immune System R-HSA-168256
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
Regulation of Apoptosis R-HSA-169911
Signaling by NOTCH4 R-HSA-9013694
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication Pre-Initiation R-HSA-69002
Programmed Cell Death R-HSA-5357801
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
DNA Replication R-HSA-69306
Vpu mediated degradation of CD4 R-HSA-180534
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
G2/M Transition R-HSA-69275
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RAS by GAPs R-HSA-5658442
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Developmental Biology R-HSA-1266738
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Defective CFTR causes cystic fibrosis R-HSA-5678895
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'off' state R-HSA-5610787
Vif-mediated degradation of APOBEC3G R-HSA-180585
Asymmetric localization of PCP proteins R-HSA-4608870
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI2 by the proteasome R-HSA-5610783
Neddylation R-HSA-8951664
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
UCH proteinases R-HSA-5689603
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
KEAP1-NFE2L2 pathway R-HSA-9755511
Stabilization of p53 R-HSA-69541
Signal Transduction R-HSA-162582
Metabolism of polyamines R-HSA-351202
TCR signaling R-HSA-202403
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stimuli R-HSA-8953897
Assembly of the pre-replicative complex R-HSA-68867
Orc1 removal from chromatin R-HSA-68949
Disease R-HSA-1643685
Interleukin-1 signaling R-HSA-9020702
RNA Polymerase II Transcription R-HSA-73857
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants abrogate ligand secretion R-HSA-5387390
FCERI mediated NF-kB activation R-HSA-2871837
Activation of NF-kappaB in B cells R-HSA-1169091
HIV Infection R-HSA-162906
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Hedgehog R-HSA-5358351
Signaling by Interleukins R-HSA-449147
Post-translational protein modification R-HSA-597592
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
p53-Independent DNA Damage Response R-HSA-69610
Ub-specific processing proteases R-HSA-5689880
Synthesis of DNA R-HSA-69239
Mitotic Anaphase R-HSA-68882
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
MAPK family signaling cascades R-HSA-5683057
S Phase R-HSA-69242
Switching of origins to a post-replicative state R-HSA-69052
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transport of small molecules R-HSA-382551
Signaling by NOTCH R-HSA-157118
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Infectious disease R-HSA-5663205
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic G1 phase and G1/S transition R-HSA-453279
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog 'on' state R-HSA-5632684
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle Checkpoints R-HSA-69620
MAPK6/MAPK4 signaling R-HSA-5687128
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stress R-HSA-2262752
ER-Phagosome pathway R-HSA-1236974
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Dependent G1 DNA Damage Response R-HSA-69563
Deubiquitination R-HSA-5688426
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
Cell Cycle R-HSA-1640170
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of amino acids and derivatives R-HSA-71291
Separation of Sister Chromatids R-HSA-2467813
Class I MHC mediated antigen processing & presentation R-HSA-983169
Assembly of the pre-replicative complex R-HSA-68867
UCH proteinases R-HSA-5689603
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic G2-G2/M phases R-HSA-453274
PTEN Regulation R-HSA-6807070
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stimuli R-HSA-8953897
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Programmed Cell Death R-HSA-5357801
Neddylation R-HSA-8951664
Mitotic G1 phase and G1/S transition R-HSA-453279
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants abrogate ligand secretion R-HSA-5387390
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication Pre-Initiation R-HSA-69002
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PCP/CE pathway R-HSA-4086400
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of DVL R-HSA-4641258
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Intracellular signaling by second messengers R-HSA-9006925
Axon guidance R-HSA-422475
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism R-HSA-1430728
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-1 family signaling R-HSA-446652
Apoptosis R-HSA-109581
Signaling by WNT R-HSA-195721
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
Innate Immune System R-HSA-168249
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Checkpoints R-HSA-69481
Metabolism of amino acids and derivatives R-HSA-71291
DNA Replication R-HSA-69306
Mitotic Metaphase and Anaphase R-HSA-2555396
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
Transcriptional regulation by RUNX2 R-HSA-8878166
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Interleukin-1 signaling R-HSA-9020702
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of proteins R-HSA-392499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G1/S Transition R-HSA-69206
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog ligand biogenesis R-HSA-5358346
FCERI mediated NF-kB activation R-HSA-2871837
HIV Infection R-HSA-162906
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Separation of Sister Chromatids R-HSA-2467813
Post-translational protein modification R-HSA-597592
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
RAF/MAP kinase cascade R-HSA-5673001
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Orc1 removal from chromatin R-HSA-68949
Adaptive Immune System R-HSA-1280218
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to hypoxia R-HSA-1234174
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transcriptional regulation by RUNX3 R-HSA-8878159
Immune System R-HSA-168256
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nuclear events mediated by NFE2L2 R-HSA-9759194
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of Apoptosis R-HSA-169911
Signaling by Hedgehog R-HSA-5358351
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Synthesis of DNA R-HSA-69239
Degradation of AXIN R-HSA-4641257
Vpu mediated degradation of CD4 R-HSA-180534
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
S Phase R-HSA-69242
M Phase R-HSA-68886
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Anaphase R-HSA-68882
Regulation of RUNX3 expression and activity R-HSA-8941858
Disorders of transmembrane transporters R-HSA-5619115
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
CLEC7A (Dectin-1) signaling R-HSA-5607764
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle R-HSA-1640170
Downstream TCR signaling R-HSA-202424
Hh mutants are degraded by ERAD R-HSA-5362768
Cell Cycle, Mitotic R-HSA-69278
Switching of origins to a post-replicative state R-HSA-69052
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of GLI2 by the proteasome R-HSA-5610783
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
MAPK6/MAPK4 signaling R-HSA-5687128
C-type lectin receptors (CLRs) R-HSA-5621481
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
Deubiquitination R-HSA-5688426
Defective CFTR causes cystic fibrosis R-HSA-5678895
TCR signaling R-HSA-202403
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular response to chemical stress R-HSA-9711123
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ABC-family proteins mediated transport R-HSA-382556
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH4 R-HSA-9013694
Negative regulation of NOTCH4 signaling R-HSA-9604323
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK1/MAPK3 signaling R-HSA-5684996
KEAP1-NFE2L2 pathway R-HSA-9755511
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Ub-specific processing proteases R-HSA-5689880
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ABC transporter disorders R-HSA-5619084
G1/S DNA Damage Checkpoints R-HSA-69615
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signal Transduction R-HSA-162582
Metabolism of polyamines R-HSA-351202
p53-Independent DNA Damage Response R-HSA-69610
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Developmental Biology R-HSA-1266738
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX2 R-HSA-8878166
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PTEN Regulation R-HSA-6807070
Regulation of RUNX2 expression and activity R-HSA-8939902
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Metabolism R-HSA-1430728
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cellular responses to stress R-HSA-2262752
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interleukin-1 signaling R-HSA-9020702
Infectious disease R-HSA-5663205
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signal Transduction R-HSA-162582
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
ABC-family proteins mediated transport R-HSA-382556
Separation of Sister Chromatids R-HSA-2467813
Regulation of Apoptosis R-HSA-169911
Generic Transcription Pathway R-HSA-212436
Cell Cycle, Mitotic R-HSA-69278
MAPK6/MAPK4 signaling R-HSA-5687128
UCH proteinases R-HSA-5689603
p53-Independent DNA Damage Response R-HSA-69610
Activation of NF-kappaB in B cells R-HSA-1169091
Neddylation R-HSA-8951664
Metabolism of amino acids and derivatives R-HSA-71291
G1/S Transition R-HSA-69206
Signaling by the B Cell Receptor (BCR) R-HSA-983705
S Phase R-HSA-69242
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of proteins R-HSA-392499
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Stabilization of p53 R-HSA-69541
Signaling by Interleukins R-HSA-449147
G1/S DNA Damage Checkpoints R-HSA-69615
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Innate Immune System R-HSA-168249
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
DNA Replication Pre-Initiation R-HSA-69002
FCERI mediated NF-kB activation R-HSA-2871837
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic G2-G2/M phases R-HSA-453274
Defective CFTR causes cystic fibrosis R-HSA-5678895
M Phase R-HSA-68886
HIV Infection R-HSA-162906
Apoptosis R-HSA-109581
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX3 R-HSA-8878159
ABC transporter disorders R-HSA-5619084
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog ligand biogenesis R-HSA-5358346
Adaptive Immune System R-HSA-1280218
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by Hedgehog R-HSA-5358351
Orc1 removal from chromatin R-HSA-68949
ER-Phagosome pathway R-HSA-1236974
RNA Polymerase II Transcription R-HSA-73857
Degradation of AXIN R-HSA-4641257
Assembly of the pre-replicative complex R-HSA-68867
Cellular response to hypoxia R-HSA-1234174
Switching of origins to a post-replicative state R-HSA-69052
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of beta-catenin by the destruction complex R-HSA-195253
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Interleukin-1 family signaling R-HSA-446652
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic Anaphase R-HSA-68882
Cellular responses to stimuli R-HSA-8953897
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Intracellular signaling by second messengers R-HSA-9006925
Cellular response to chemical stress R-HSA-9711123
Cyclin E associated events during G1/S transition R-HSA-69202
Vpu mediated degradation of CD4 R-HSA-180534
Host Interactions of HIV factors R-HSA-162909
Hh mutants abrogate ligand secretion R-HSA-5387390
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of mitotic cell cycle R-HSA-453276
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RAF/MAP kinase cascade R-HSA-5673001
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
TCR signaling R-HSA-202403
Post-translational protein modification R-HSA-597592
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RAS by GAPs R-HSA-5658442
Ub-specific processing proteases R-HSA-5689880
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
G2/M Checkpoints R-HSA-69481
Signaling by NOTCH R-HSA-157118
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Negative regulation of NOTCH4 signaling R-HSA-9604323
C-type lectin receptors (CLRs) R-HSA-5621481
Downstream TCR signaling R-HSA-202424
Gene expression (Transcription) R-HSA-74160
Hedgehog 'on' state R-HSA-5632684
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by WNT R-HSA-195721
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Axon guidance R-HSA-422475
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transport of small molecules R-HSA-382551
Degradation of GLI1 by the proteasome R-HSA-5610780
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle R-HSA-1640170
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants are degraded by ERAD R-HSA-5362768
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by ROBO receptors R-HSA-376176
PCP/CE pathway R-HSA-4086400
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX3 expression and activity R-HSA-8941858
MAPK family signaling cascades R-HSA-5683057
DNA Replication R-HSA-69306
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX1 R-HSA-8878171
Asymmetric localization of PCP proteins R-HSA-4608870
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of RNA R-HSA-8953854
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of DVL R-HSA-4641258
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Vpu mediated degradation of CD4 R-HSA-180534
Signal Transduction R-HSA-162582
Metabolism of amino acids and derivatives R-HSA-71291
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of mitotic cell cycle R-HSA-453276
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of AXIN R-HSA-4641257
Ub-specific processing proteases R-HSA-5689880
Nervous system development R-HSA-9675108
Metabolism R-HSA-1430728
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Asymmetric localization of PCP proteins R-HSA-4608870
Immune System R-HSA-168256
PIP3 activates AKT signaling R-HSA-1257604
Degradation of DVL R-HSA-4641258
Cell Cycle R-HSA-1640170
MAPK family signaling cascades R-HSA-5683057
G2/M Transition R-HSA-69275
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Negative regulation of NOTCH4 signaling R-HSA-9604323
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PCP/CE pathway R-HSA-4086400
Cellular response to hypoxia R-HSA-1234174
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Cell Cycle Checkpoints R-HSA-69620
Degradation of GLI2 by the proteasome R-HSA-5610783
Mitotic Metaphase and Anaphase R-HSA-2555396
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of RNA R-HSA-8953854
ABC-family proteins mediated transport R-HSA-382556
Axon guidance R-HSA-422475
Host Interactions of HIV factors R-HSA-162909
Deubiquitination R-HSA-5688426
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
p53-Dependent G1 DNA Damage Response R-HSA-69563
FCERI mediated NF-kB activation R-HSA-2871837
Synthesis of DNA R-HSA-69239
Adaptive Immune System R-HSA-1280218
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 signaling R-HSA-9020702
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by ROBO receptors R-HSA-376176
Signaling by NOTCH4 R-HSA-9013694
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stress R-HSA-2262752
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
M Phase R-HSA-68886
Stabilization of p53 R-HSA-69541
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing-Cross presentation R-HSA-1236975
Signaling by Interleukins R-HSA-449147
G1/S Transition R-HSA-69206
Apoptosis R-HSA-109581
Mitotic Anaphase R-HSA-68882
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of polyamines R-HSA-351202
TCF dependent signaling in response to WNT R-HSA-201681
Assembly of the pre-replicative complex R-HSA-68867
Developmental Biology R-HSA-1266738
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX3 R-HSA-8878159
Downstream TCR signaling R-HSA-202424
ER-Phagosome pathway R-HSA-1236974
MAPK1/MAPK3 signaling R-HSA-5684996
Infectious disease R-HSA-5663205
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G2-G2/M phases R-HSA-453274
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog 'on' state R-HSA-5632684
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular response to chemical stress R-HSA-9711123
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
Disease R-HSA-1643685
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Innate Immune System R-HSA-168249
Separation of Sister Chromatids R-HSA-2467813
RNA Polymerase II Transcription R-HSA-73857
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by WNT R-HSA-195721
NIK-->noncanonical NF-kB signaling R-HSA-5676590
G2/M Checkpoints R-HSA-69481
Transport of small molecules R-HSA-382551
Hedgehog 'off' state R-HSA-5610787
DNA Replication R-HSA-69306
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of Apoptosis R-HSA-169911
PTEN Regulation R-HSA-6807070
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vif-mediated degradation of APOBEC3G R-HSA-180585
Post-translational protein modification R-HSA-597592
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
S Phase R-HSA-69242
Orc1 removal from chromatin R-HSA-68949
p53-Independent DNA Damage Response R-HSA-69610
Regulation of PTEN stability and activity R-HSA-8948751
DNA Replication Pre-Initiation R-HSA-69002
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of RAS by GAPs R-HSA-5658442
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hh mutants are degraded by ERAD R-HSA-5362768
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog ligand biogenesis R-HSA-5358346
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disorders of transmembrane transporters R-HSA-5619115
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Nuclear events mediated by NFE2L2 R-HSA-9759194
DNA Replication R-HSA-69306
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PTEN Regulation R-HSA-6807070
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of RNA R-HSA-8953854
MAPK family signaling cascades R-HSA-5683057
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
FCERI mediated NF-kB activation R-HSA-2871837
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by ROBO receptors R-HSA-376176
Hedgehog ligand biogenesis R-HSA-5358346
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cell Cycle, Mitotic R-HSA-69278
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by NOTCH R-HSA-157118
UCH proteinases R-HSA-5689603
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of polyamines R-HSA-351202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RAF/MAP kinase cascade R-HSA-5673001
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX2 R-HSA-8878166
Stabilization of p53 R-HSA-69541
G2/M Checkpoints R-HSA-69481
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by WNT R-HSA-195721
Intracellular signaling by second messengers R-HSA-9006925
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Developmental Biology R-HSA-1266738
G2/M Transition R-HSA-69275
Interleukin-1 family signaling R-HSA-446652
TCR signaling R-HSA-202403
Programmed Cell Death R-HSA-5357801
Separation of Sister Chromatids R-HSA-2467813
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of RAS by GAPs R-HSA-5658442
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK6/MAPK4 signaling R-HSA-5687128
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of GLI2 by the proteasome R-HSA-5610783
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX3 expression and activity R-HSA-8941858
MAPK1/MAPK3 signaling R-HSA-5684996
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by Hedgehog R-HSA-5358351
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
Infectious disease R-HSA-5663205
Cell Cycle Checkpoints R-HSA-69620
ABC-family proteins mediated transport R-HSA-382556
Nervous system development R-HSA-9675108
Hedgehog 'off' state R-HSA-5610787
Signal Transduction R-HSA-162582
Degradation of AXIN R-HSA-4641257
Mitotic G1 phase and G1/S transition R-HSA-453279
Axon guidance R-HSA-422475
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Immune System R-HSA-168256
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Adaptive Immune System R-HSA-1280218
Cellular responses to stress R-HSA-2262752
M Phase R-HSA-68886
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'on' state R-HSA-5632684
Cellular response to hypoxia R-HSA-1234174
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of DVL R-HSA-4641258
Negative regulation of NOTCH4 signaling R-HSA-9604323
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Deubiquitination R-HSA-5688426
Cellular responses to stimuli R-HSA-8953897
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX1 R-HSA-8878171
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX3 R-HSA-8878159
Asymmetric localization of PCP proteins R-HSA-4608870
Apoptosis R-HSA-109581
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular response to chemical stress R-HSA-9711123
Metabolism of proteins R-HSA-392499
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
PCP/CE pathway R-HSA-4086400
Innate Immune System R-HSA-168249
Assembly of the pre-replicative complex R-HSA-68867
Neddylation R-HSA-8951664
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH4 R-HSA-9013694
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 signaling R-HSA-9020702
Regulation of PTEN stability and activity R-HSA-8948751
DNA Replication Pre-Initiation R-HSA-69002
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ER-Phagosome pathway R-HSA-1236974
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by Interleukins R-HSA-449147
Class I MHC mediated antigen processing & presentation R-HSA-983169
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S Transition R-HSA-69206
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Downstream TCR signaling R-HSA-202424
Transport of small molecules R-HSA-382551
Switching of origins to a post-replicative state R-HSA-69052
Mitotic G2-G2/M phases R-HSA-453274
C-type lectin receptors (CLRs) R-HSA-5621481
Synthesis of DNA R-HSA-69239
Regulation of mitotic cell cycle R-HSA-453276
Gene expression (Transcription) R-HSA-74160
Disorders of transmembrane transporters R-HSA-5619115
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of GLI1 by the proteasome R-HSA-5610780
PIP3 activates AKT signaling R-HSA-1257604
Post-translational protein modification R-HSA-597592
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
Metabolism R-HSA-1430728
Axon guidance R-HSA-422475
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
HIV Infection R-HSA-162906
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of DVL R-HSA-4641258
Host Interactions of HIV factors R-HSA-162909
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Hedgehog R-HSA-5358351
Signaling by Interleukins R-HSA-449147
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
RAF/MAP kinase cascade R-HSA-5673001
Nuclear events mediated by NFE2L2 R-HSA-9759194
ABC-family proteins mediated transport R-HSA-382556
Innate Immune System R-HSA-168249
DNA Replication Pre-Initiation R-HSA-69002
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Regulation of RAS by GAPs R-HSA-5658442
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by ROBO receptors R-HSA-376176
Class I MHC mediated antigen processing & presentation R-HSA-983169
PCP/CE pathway R-HSA-4086400
p53-Dependent G1 DNA Damage Response R-HSA-69563
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of AXIN R-HSA-4641257
DNA Replication R-HSA-69306
Negative regulation of NOTCH4 signaling R-HSA-9604323
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic G2-G2/M phases R-HSA-453274
FCERI mediated NF-kB activation R-HSA-2871837
Synthesis of DNA R-HSA-69239
Signal Transduction R-HSA-162582
Infectious disease R-HSA-5663205
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Disease R-HSA-1643685
Regulation of RUNX3 expression and activity R-HSA-8941858
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Cellular responses to stimuli R-HSA-8953897
Degradation of beta-catenin by the destruction complex R-HSA-195253
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
Transcriptional regulation by RUNX3 R-HSA-8878159
Deubiquitination R-HSA-5688426
Cyclin E associated events during G1/S transition R-HSA-69202
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 signaling R-HSA-9020702
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Nervous system development R-HSA-9675108
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle, Mitotic R-HSA-69278
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by NOTCH4 R-HSA-9013694
Hh mutants are degraded by ERAD R-HSA-5362768
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Separation of Sister Chromatids R-HSA-2467813
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC transporter disorders R-HSA-5619084
Neddylation R-HSA-8951664
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream TCR signaling R-HSA-202424
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog 'on' state R-HSA-5632684
Developmental Biology R-HSA-1266738
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants abrogate ligand secretion R-HSA-5387390
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of mitotic cell cycle R-HSA-453276
Beta-catenin independent WNT signaling R-HSA-3858494
G1/S Transition R-HSA-69206
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 family signaling R-HSA-446652
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
M Phase R-HSA-68886
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by WNT R-HSA-195721
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
Cytokine Signaling in Immune system R-HSA-1280215
Vpu mediated degradation of CD4 R-HSA-180534
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Immune System R-HSA-168256
Mitotic G1 phase and G1/S transition R-HSA-453279
TCF dependent signaling in response to WNT R-HSA-201681
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Independent DNA Damage Response R-HSA-69610
Signaling by NOTCH R-HSA-157118
G2/M Transition R-HSA-69275
MAPK family signaling cascades R-HSA-5683057
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of polyamines R-HSA-351202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of PTEN stability and activity R-HSA-8948751
Switching of origins to a post-replicative state R-HSA-69052
Intracellular signaling by second messengers R-HSA-9006925
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stress R-HSA-2262752
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX1 R-HSA-8878171
PTEN Regulation R-HSA-6807070
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of amino acids and derivatives R-HSA-71291
Orc1 removal from chromatin R-HSA-68949
Adaptive Immune System R-HSA-1280218
Transport of small molecules R-HSA-382551
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of Apoptosis R-HSA-169911
S Phase R-HSA-69242
G2/M Checkpoints R-HSA-69481
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to chemical stress R-HSA-9711123
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX2 R-HSA-8878166
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to hypoxia R-HSA-1234174
ER-Phagosome pathway R-HSA-1236974
Mitotic Anaphase R-HSA-68882
Apoptosis R-HSA-109581
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle Checkpoints R-HSA-69620

Expression Atlas ENSG00000013275
NCBI gene (formerly Entrezgene) 5704
GeneCards 9551
HGNC Symbol HGNC:9551
MIM gene 602707
UniProtKB Gene Name P43686
WikiGene 5704
Gene: FAAH
Ensembl ID : ENSG00000117480
Description: fatty acid amide hydrolase
Gene Synonyms: FAAH-1
3 APIs:
131 Possible Orthologues:

Fatty acid metabolism R-HSA-8978868
Arachidonic acid metabolism R-HSA-2142753
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Fatty acid metabolism R-HSA-8978868
Metabolism of lipids R-HSA-556833
Arachidonic acid metabolism R-HSA-2142753
Metabolism R-HSA-1430728
Fatty acid metabolism R-HSA-8978868
Metabolism of lipids R-HSA-556833
Arachidonic acid metabolism R-HSA-2142753
Metabolism R-HSA-1430728
Fatty acid metabolism R-HSA-8978868
Metabolism R-HSA-1430728
Arachidonic acid metabolism R-HSA-2142753
Metabolism of lipids R-HSA-556833
Metabolism of lipids R-HSA-556833
Fatty acid metabolism R-HSA-8978868
Arachidonic acid metabolism R-HSA-2142753
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Fatty acid metabolism R-HSA-8978868
Metabolism of lipids R-HSA-556833
Arachidonic acid metabolism R-HSA-2142753
Metabolism R-HSA-1430728
Arachidonic acid metabolism R-HSA-2142753
Metabolism of lipids R-HSA-556833
Fatty acid metabolism R-HSA-8978868
Arachidonic acid metabolism R-HSA-2142753
Metabolism of lipids R-HSA-556833
Fatty acid metabolism R-HSA-8978868
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Fatty acid metabolism R-HSA-8978868
Metabolism R-HSA-1430728
Arachidonic acid metabolism R-HSA-2142753
Arachidonic acid metabolism R-HSA-2142753
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Fatty acid metabolism R-HSA-8978868

Expression Atlas ENSG00000117480
NCBI gene (formerly Entrezgene) 2166
GeneCards 3553
HGNC Symbol HGNC:3553
MIM gene 602935
MIM morbid 606581
UniProtKB Gene Name O00519
WikiGene 2166
Gene: PSMB11
Ensembl ID : ENSG00000222028
Description: proteasome subunit beta 11
Gene Synonyms: BETA5T
6 APIs:
228 Possible Orthologues:

Cytokine Signaling in Immune system R-HSA-1280215
TCR signaling R-HSA-202403
Signaling by Interleukins R-HSA-449147
Programmed Cell Death R-HSA-5357801
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G2/M Transition R-HSA-69275
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism R-HSA-1430728
ER-Phagosome pathway R-HSA-1236974
ABC transporter disorders R-HSA-5619084
S Phase R-HSA-69242
Hedgehog 'off' state R-HSA-5610787
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of polyamines R-HSA-351202
Separation of Sister Chromatids R-HSA-2467813
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
p53-Independent DNA Damage Response R-HSA-69610
ABC-family proteins mediated transport R-HSA-382556
Innate Immune System R-HSA-168249
Regulation of mitotic cell cycle R-HSA-453276
Deubiquitination R-HSA-5688426
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic G2-G2/M phases R-HSA-453274
Immune System R-HSA-168256
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stimuli R-HSA-8953897
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX2 R-HSA-8878166
Post-translational protein modification R-HSA-597592
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI2 by the proteasome R-HSA-5610783
RAF/MAP kinase cascade R-HSA-5673001
Degradation of AXIN R-HSA-4641257
Axon guidance R-HSA-422475
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle, Mitotic R-HSA-69278
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Dependent G1 DNA Damage Response R-HSA-69563
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Switching of origins to a post-replicative state R-HSA-69052
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hedgehog 'on' state R-HSA-5632684
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of DVL R-HSA-4641258
Cell Cycle R-HSA-1640170
Mitotic Anaphase R-HSA-68882
Cellular response to chemical stress R-HSA-9711123
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
HIV Infection R-HSA-162906
Hh mutants are degraded by ERAD R-HSA-5362768
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of NF-kappaB in B cells R-HSA-1169091
Ub-specific processing proteases R-HSA-5689880
Synthesis of DNA R-HSA-69239
Transport of small molecules R-HSA-382551
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 signaling R-HSA-9020702
Downstream TCR signaling R-HSA-202424
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
Regulation of Apoptosis R-HSA-169911
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI1 by the proteasome R-HSA-5610780
Antigen processing-Cross presentation R-HSA-1236975
Signaling by WNT R-HSA-195721
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of PTEN stability and activity R-HSA-8948751
Infectious disease R-HSA-5663205
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
C-type lectin receptors (CLRs) R-HSA-5621481
Apoptosis R-HSA-109581
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hh mutants abrogate ligand secretion R-HSA-5387390
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX1 R-HSA-8878171
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of beta-catenin by the destruction complex R-HSA-195253
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Interleukin-1 family signaling R-HSA-446652
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G1/S DNA Damage Checkpoints R-HSA-69615
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular response to hypoxia R-HSA-1234174
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Hedgehog R-HSA-5358351
Separation of Sister Chromatids R-HSA-2467813
Metabolism of RNA R-HSA-8953854
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Metabolism R-HSA-1430728
Programmed Cell Death R-HSA-5357801
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of AXIN R-HSA-4641257
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of polyamines R-HSA-351202
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
Beta-catenin independent WNT signaling R-HSA-3858494
ER-Phagosome pathway R-HSA-1236974
Hedgehog ligand biogenesis R-HSA-5358346
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
ABC-family proteins mediated transport R-HSA-382556
MAPK family signaling cascades R-HSA-5683057
Post-translational protein modification R-HSA-597592
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of Apoptosis R-HSA-169911
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Hedgehog R-HSA-5358351
G2/M Checkpoints R-HSA-69481
Interleukin-1 signaling R-HSA-9020702
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
Mitotic Anaphase R-HSA-68882
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX1 R-HSA-8878171
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stimuli R-HSA-8953897
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI2 by the proteasome R-HSA-5610783
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of amino acids and derivatives R-HSA-71291
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX2 R-HSA-8878166
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Replication R-HSA-69306
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Deubiquitination R-HSA-5688426
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Transport of small molecules R-HSA-382551
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream TCR signaling R-HSA-202424
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of DVL R-HSA-4641258
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mitotic cell cycle R-HSA-453276
Interleukin-1 family signaling R-HSA-446652
Regulation of RAS by GAPs R-HSA-5658442
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RNA Polymerase II Transcription R-HSA-73857
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Axon guidance R-HSA-422475
PIP3 activates AKT signaling R-HSA-1257604
Activation of NF-kappaB in B cells R-HSA-1169091
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic Metaphase and Anaphase R-HSA-2555396
Class I MHC mediated antigen processing & presentation R-HSA-983169
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of proteins R-HSA-392499
Hh mutants are degraded by ERAD R-HSA-5362768
MAPK6/MAPK4 signaling R-HSA-5687128
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Interleukins R-HSA-449147
PCP/CE pathway R-HSA-4086400
Immune System R-HSA-168256
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
ABC transporter disorders R-HSA-5619084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Intracellular signaling by second messengers R-HSA-9006925
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hedgehog 'on' state R-HSA-5632684
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular response to hypoxia R-HSA-1234174
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle Checkpoints R-HSA-69620
NIK-->noncanonical NF-kB signaling R-HSA-5676590
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic G2-G2/M phases R-HSA-453274
Immune System R-HSA-168256
Hh mutants abrogate ligand secretion R-HSA-5387390
ABC-family proteins mediated transport R-HSA-382556
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Axon guidance R-HSA-422475
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
Metabolism R-HSA-1430728
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RAS by GAPs R-HSA-5658442
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'off' state R-HSA-5610787
Hh mutants are degraded by ERAD R-HSA-5362768
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CLEC7A (Dectin-1) signaling R-HSA-5607764
Intracellular signaling by second messengers R-HSA-9006925
Separation of Sister Chromatids R-HSA-2467813
Neddylation R-HSA-8951664
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Interleukins R-HSA-449147
Stabilization of p53 R-HSA-69541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular responses to stress R-HSA-2262752
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to hypoxia R-HSA-1234174
Degradation of GLI1 by the proteasome R-HSA-5610780
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of NF-kappaB in B cells R-HSA-1169091
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Gene expression (Transcription) R-HSA-74160
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Vif-mediated degradation of APOBEC3G R-HSA-180585
Nervous system development R-HSA-9675108
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
S Phase R-HSA-69242
Mitotic Metaphase and Anaphase R-HSA-2555396
Post-translational protein modification R-HSA-597592
HIV Infection R-HSA-162906
Apoptosis R-HSA-109581
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Deubiquitination R-HSA-5688426
Vpu mediated degradation of CD4 R-HSA-180534
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 signaling R-HSA-9020702
Developmental Biology R-HSA-1266738
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Innate Immune System R-HSA-168249
Hedgehog ligand biogenesis R-HSA-5358346
Switching of origins to a post-replicative state R-HSA-69052
G2/M Checkpoints R-HSA-69481
Programmed Cell Death R-HSA-5357801
Cellular responses to stimuli R-HSA-8953897
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PIP3 activates AKT signaling R-HSA-1257604
FCERI mediated NF-kB activation R-HSA-2871837
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of mitotic cell cycle R-HSA-453276
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
M Phase R-HSA-68886
Interleukin-1 family signaling R-HSA-446652
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disorders of transmembrane transporters R-HSA-5619115
Host Interactions of HIV factors R-HSA-162909
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by WNT R-HSA-195721
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent DNA Damage Response R-HSA-69610
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog 'on' state R-HSA-5632684
Metabolism of proteins R-HSA-392499
Cellular response to chemical stress R-HSA-9711123
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by ROBO receptors R-HSA-376176
Orc1 removal from chromatin R-HSA-68949
ABC transporter disorders R-HSA-5619084
Regulation of RUNX2 expression and activity R-HSA-8939902
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
RNA Polymerase II Transcription R-HSA-73857
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Infectious disease R-HSA-5663205
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
DNA Replication R-HSA-69306
Synthesis of DNA R-HSA-69239
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
UCH proteinases R-HSA-5689603
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK family signaling cascades R-HSA-5683057
PTEN Regulation R-HSA-6807070
Cell Cycle R-HSA-1640170
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of polyamines R-HSA-351202
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
Mitotic Anaphase R-HSA-68882
Degradation of DVL R-HSA-4641258
Transcriptional regulation by RUNX2 R-HSA-8878166
Disease R-HSA-1643685
PCP/CE pathway R-HSA-4086400
G2/M Transition R-HSA-69275
Innate Immune System R-HSA-168249
G2/M Checkpoints R-HSA-69481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Hh mutants are degraded by ERAD R-HSA-5362768
G1/S DNA Damage Checkpoints R-HSA-69615
Neddylation R-HSA-8951664
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Defective CFTR causes cystic fibrosis R-HSA-5678895
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
G2/M Transition R-HSA-69275
Cellular response to hypoxia R-HSA-1234174
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of amino acids and derivatives R-HSA-71291
Immune System R-HSA-168256
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
ABC transporter disorders R-HSA-5619084
Hedgehog 'off' state R-HSA-5610787
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
Switching of origins to a post-replicative state R-HSA-69052
Ub-specific processing proteases R-HSA-5689880
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular response to chemical stress R-HSA-9711123
Signaling by Hedgehog R-HSA-5358351
Interleukin-1 family signaling R-HSA-446652
Cell Cycle, Mitotic R-HSA-69278
Degradation of AXIN R-HSA-4641257
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of expression of SLITs and ROBOs R-HSA-9010553
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Adaptive Immune System R-HSA-1280218
Signaling by Interleukins R-HSA-449147
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by WNT R-HSA-195721
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Separation of Sister Chromatids R-HSA-2467813
Orc1 removal from chromatin R-HSA-68949
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by ROBO receptors R-HSA-376176
Regulation of RUNX2 expression and activity R-HSA-8939902
Disease R-HSA-1643685
Metabolism of polyamines R-HSA-351202
Mitotic G2-G2/M phases R-HSA-453274
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
DNA Replication R-HSA-69306
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
PCP/CE pathway R-HSA-4086400
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent DNA Damage Response R-HSA-69610
ABC-family proteins mediated transport R-HSA-382556
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
HIV Infection R-HSA-162906
Apoptosis R-HSA-109581
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK family signaling cascades R-HSA-5683057
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Vif-mediated degradation of APOBEC3G R-HSA-180585
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transport of small molecules R-HSA-382551
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI2 by the proteasome R-HSA-5610783
CLEC7A (Dectin-1) signaling R-HSA-5607764
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of Apoptosis R-HSA-169911
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle R-HSA-1640170
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Beta-catenin independent WNT signaling R-HSA-3858494
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cytokine Signaling in Immune system R-HSA-1280215
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stimuli R-HSA-8953897
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Synthesis of DNA R-HSA-69239
Axon guidance R-HSA-422475
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Programmed Cell Death R-HSA-5357801
Stabilization of p53 R-HSA-69541
UCH proteinases R-HSA-5689603
Class I MHC mediated antigen processing & presentation R-HSA-983169
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX1 R-HSA-8878171
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular responses to stress R-HSA-2262752
Synthesis of DNA R-HSA-69239
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
MAPK6/MAPK4 signaling R-HSA-5687128
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'off' state R-HSA-5610787
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Defective CFTR causes cystic fibrosis R-HSA-5678895
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
TCR signaling R-HSA-202403
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of polyamines R-HSA-351202
Signaling by ROBO receptors R-HSA-376176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Immune System R-HSA-168256
Signaling by Hedgehog R-HSA-5358351
RAF/MAP kinase cascade R-HSA-5673001
Post-translational protein modification R-HSA-597592
Metabolism of RNA R-HSA-8953854
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Disease R-HSA-1643685
Degradation of DVL R-HSA-4641258
Adaptive Immune System R-HSA-1280218
Cell Cycle, Mitotic R-HSA-69278
Signaling by WNT R-HSA-195721
Metabolism of amino acids and derivatives R-HSA-71291
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
Apoptosis R-HSA-109581
ER-Phagosome pathway R-HSA-1236974
KEAP1-NFE2L2 pathway R-HSA-9755511
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI2 by the proteasome R-HSA-5610783
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
UCH proteinases R-HSA-5689603
S Phase R-HSA-69242
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Deubiquitination R-HSA-5688426
CLEC7A (Dectin-1) signaling R-HSA-5607764
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Separation of Sister Chromatids R-HSA-2467813
Transport of small molecules R-HSA-382551
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Host Interactions of HIV factors R-HSA-162909
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PCP/CE pathway R-HSA-4086400
Downstream TCR signaling R-HSA-202424
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
Interleukin-1 signaling R-HSA-9020702
Hh mutants abrogate ligand secretion R-HSA-5387390
TCF dependent signaling in response to WNT R-HSA-201681
Infectious disease R-HSA-5663205
Degradation of AXIN R-HSA-4641257
ABC-family proteins mediated transport R-HSA-382556
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Anaphase R-HSA-68882
ABC transporter disorders R-HSA-5619084
Orc1 removal from chromatin R-HSA-68949
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
PTEN Regulation R-HSA-6807070
Hedgehog 'on' state R-HSA-5632684
Innate Immune System R-HSA-168249
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Replication R-HSA-69306
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic Metaphase and Anaphase R-HSA-2555396
Neddylation R-HSA-8951664
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to hypoxia R-HSA-1234174
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic G2-G2/M phases R-HSA-453274
Axon guidance R-HSA-422475
Regulation of Apoptosis R-HSA-169911
Programmed Cell Death R-HSA-5357801
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Stabilization of p53 R-HSA-69541
C-type lectin receptors (CLRs) R-HSA-5621481
HIV Infection R-HSA-162906
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
Metabolism of amino acids and derivatives R-HSA-71291
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Ub-specific processing proteases R-HSA-5689880
ABC-family proteins mediated transport R-HSA-382556
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
Downstream TCR signaling R-HSA-202424
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vif-mediated degradation of APOBEC3G R-HSA-180585
CLEC7A (Dectin-1) signaling R-HSA-5607764
ER-Phagosome pathway R-HSA-1236974
Cell Cycle R-HSA-1640170
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle, Mitotic R-HSA-69278
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Infectious disease R-HSA-5663205
Asymmetric localization of PCP proteins R-HSA-4608870
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of RAS by GAPs R-HSA-5658442
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Orc1 removal from chromatin R-HSA-68949
Metabolism R-HSA-1430728
p53-Dependent G1 DNA Damage Response R-HSA-69563
Programmed Cell Death R-HSA-5357801
RAF/MAP kinase cascade R-HSA-5673001
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
Regulation of PTEN stability and activity R-HSA-8948751
Host Interactions of HIV factors R-HSA-162909
C-type lectin receptors (CLRs) R-HSA-5621481
Signal Transduction R-HSA-162582
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 signaling R-HSA-9020702
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI1 by the proteasome R-HSA-5610780
UCH proteinases R-HSA-5689603
Gene expression (Transcription) R-HSA-74160
Hedgehog ligand biogenesis R-HSA-5358346
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of RNA R-HSA-8953854
Degradation of DVL R-HSA-4641258
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of polyamines R-HSA-351202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'on' state R-HSA-5632684
Intracellular signaling by second messengers R-HSA-9006925
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Transport of small molecules R-HSA-382551
Regulation of RUNX2 expression and activity R-HSA-8939902
Post-translational protein modification R-HSA-597592
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TCR signaling R-HSA-202403
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic G2-G2/M phases R-HSA-453274
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Immune System R-HSA-168256
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PCP/CE pathway R-HSA-4086400
Degradation of GLI2 by the proteasome R-HSA-5610783
Apoptosis R-HSA-109581
Neddylation R-HSA-8951664
PTEN Regulation R-HSA-6807070
Vpu mediated degradation of CD4 R-HSA-180534
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Interleukins R-HSA-449147
Beta-catenin independent WNT signaling R-HSA-3858494
Hh mutants abrogate ligand secretion R-HSA-5387390
Adaptive Immune System R-HSA-1280218
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
Disease R-HSA-1643685
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Switching of origins to a post-replicative state R-HSA-69052
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Stabilization of p53 R-HSA-69541
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of AXIN R-HSA-4641257
Separation of Sister Chromatids R-HSA-2467813
Nervous system development R-HSA-9675108
Interleukin-1 family signaling R-HSA-446652
M Phase R-HSA-68886
Signaling by ROBO receptors R-HSA-376176
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ABC transporter disorders R-HSA-5619084
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by Hedgehog R-HSA-5358351
Synthesis of DNA R-HSA-69239
Cellular response to chemical stress R-HSA-9711123
Regulation of Apoptosis R-HSA-169911
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Innate Immune System R-HSA-168249
Degradation of beta-catenin by the destruction complex R-HSA-195253
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Anaphase R-HSA-68882
Antigen processing-Cross presentation R-HSA-1236975
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle Checkpoints R-HSA-69620
Cellular response to hypoxia R-HSA-1234174
Deubiquitination R-HSA-5688426
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hedgehog 'off' state R-HSA-5610787
Neddylation R-HSA-8951664
KEAP1-NFE2L2 pathway R-HSA-9755511
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Antigen processing-Cross presentation R-HSA-1236975
G2/M Transition R-HSA-69275
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Anaphase R-HSA-68882
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK family signaling cascades R-HSA-5683057
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
Hh mutants abrogate ligand secretion R-HSA-5387390
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
HIV Infection R-HSA-162906
Hedgehog ligand biogenesis R-HSA-5358346
Hedgehog 'off' state R-HSA-5610787
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 family signaling R-HSA-446652
FCERI mediated NF-kB activation R-HSA-2871837
ER-Phagosome pathway R-HSA-1236974
Regulation of mitotic cell cycle R-HSA-453276
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
UCH proteinases R-HSA-5689603
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Separation of Sister Chromatids R-HSA-2467813
Host Interactions of HIV factors R-HSA-162909
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Disorders of transmembrane transporters R-HSA-5619115
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Hedgehog R-HSA-5358351
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of RUNX2 expression and activity R-HSA-8939902
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transport of small molecules R-HSA-382551
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
RNA Polymerase II Transcription R-HSA-73857
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
Degradation of AXIN R-HSA-4641257
p53-Independent DNA Damage Response R-HSA-69610
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by Interleukins R-HSA-449147
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular responses to stimuli R-HSA-8953897
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Gene expression (Transcription) R-HSA-74160
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism R-HSA-1430728
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Stabilization of p53 R-HSA-69541
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI2 by the proteasome R-HSA-5610783
DNA Replication R-HSA-69306
Mitotic Metaphase and Anaphase R-HSA-2555396
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vif-mediated degradation of APOBEC3G R-HSA-180585
S Phase R-HSA-69242
Apoptosis R-HSA-109581
Cellular response to chemical stress R-HSA-9711123
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle Checkpoints R-HSA-69620
Signal Transduction R-HSA-162582
Hedgehog 'on' state R-HSA-5632684
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of Apoptosis R-HSA-169911
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Programmed Cell Death R-HSA-5357801
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX1 R-HSA-8878171
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of RNA R-HSA-8953854
Cellular response to hypoxia R-HSA-1234174
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
NIK-->noncanonical NF-kB signaling R-HSA-5676590
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Synthesis of DNA R-HSA-69239
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nervous system development R-HSA-9675108
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
RAF/MAP kinase cascade R-HSA-5673001
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cytokine Signaling in Immune system R-HSA-1280215
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Cellular responses to stimuli R-HSA-8953897
MAPK family signaling cascades R-HSA-5683057
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of GLI1 by the proteasome R-HSA-5610780
Degradation of GLI2 by the proteasome R-HSA-5610783
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Immune System R-HSA-168256
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Metaphase and Anaphase R-HSA-2555396
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Transition R-HSA-69275
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Intracellular signaling by second messengers R-HSA-9006925
G1/S DNA Damage Checkpoints R-HSA-69615
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
PIP3 activates AKT signaling R-HSA-1257604
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of amino acids and derivatives R-HSA-71291
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
HIV Infection R-HSA-162906
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
Stabilization of p53 R-HSA-69541
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by Interleukins R-HSA-449147
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle R-HSA-1640170
Signaling by ROBO receptors R-HSA-376176
Signaling by WNT R-HSA-195721
MAPK6/MAPK4 signaling R-HSA-5687128
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transport of small molecules R-HSA-382551
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of proteins R-HSA-392499
Generic Transcription Pathway R-HSA-212436
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'on' state R-HSA-5632684
Deubiquitination R-HSA-5688426
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Post-translational protein modification R-HSA-597592
TCR signaling R-HSA-202403
Developmental Biology R-HSA-1266738
Cellular response to hypoxia R-HSA-1234174
Mitotic Anaphase R-HSA-68882
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of AXIN R-HSA-4641257
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent DNA Damage Response R-HSA-69610
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ub-specific processing proteases R-HSA-5689880
Regulation of mitotic cell cycle R-HSA-453276
Separation of Sister Chromatids R-HSA-2467813
Interleukin-1 signaling R-HSA-9020702
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Disease R-HSA-1643685
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK1/MAPK3 signaling R-HSA-5684996
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of DVL R-HSA-4641258
Metabolism R-HSA-1430728
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Interleukin-1 family signaling R-HSA-446652
Hedgehog 'off' state R-HSA-5610787
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX1 R-HSA-8878171
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular responses to stress R-HSA-2262752
Cell Cycle Checkpoints R-HSA-69620
DNA Replication R-HSA-69306
PCP/CE pathway R-HSA-4086400
Gene expression (Transcription) R-HSA-74160
Apoptosis R-HSA-109581
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX2 R-HSA-8878166
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Axon guidance R-HSA-422475
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hh mutants abrogate ligand secretion R-HSA-5387390
Programmed Cell Death R-HSA-5357801
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Synthesis of DNA R-HSA-69239
ABC transporter disorders R-HSA-5619084
C-type lectin receptors (CLRs) R-HSA-5621481
Orc1 removal from chromatin R-HSA-68949
Regulation of Apoptosis R-HSA-169911
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Switching of origins to a post-replicative state R-HSA-69052
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
G2/M Checkpoints R-HSA-69481
G2/M Transition R-HSA-69275
Signaling by WNT R-HSA-195721
Metabolism of proteins R-HSA-392499
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
Switching of origins to a post-replicative state R-HSA-69052
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
Regulation of Apoptosis R-HSA-169911
Defective CFTR causes cystic fibrosis R-HSA-5678895
UCH proteinases R-HSA-5689603
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Adaptive Immune System R-HSA-1280218
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Stabilization of p53 R-HSA-69541
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Regulation of RAS by GAPs R-HSA-5658442
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of mitotic cell cycle R-HSA-453276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TCF dependent signaling in response to WNT R-HSA-201681
Gene expression (Transcription) R-HSA-74160
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog 'on' state R-HSA-5632684
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Interleukins R-HSA-449147
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nervous system development R-HSA-9675108
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Apoptosis R-HSA-109581
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI2 by the proteasome R-HSA-5610783
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Post-translational protein modification R-HSA-597592
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream TCR signaling R-HSA-202424
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Checkpoints R-HSA-69481
Metabolism R-HSA-1430728
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Class I MHC mediated antigen processing & presentation R-HSA-983169
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
Programmed Cell Death R-HSA-5357801
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S DNA Damage Checkpoints R-HSA-69615
Vpu mediated degradation of CD4 R-HSA-180534
Cellular responses to stimuli R-HSA-8953897
ER-Phagosome pathway R-HSA-1236974
Cell Cycle, Mitotic R-HSA-69278
RNA Polymerase II Transcription R-HSA-73857
Disorders of transmembrane transporters R-HSA-5619115
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
Regulation of RUNX2 expression and activity R-HSA-8939902
CLEC7A (Dectin-1) signaling R-HSA-5607764
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by Hedgehog R-HSA-5358351
Hh mutants abrogate ligand secretion R-HSA-5387390
M Phase R-HSA-68886
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PCP/CE pathway R-HSA-4086400
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell Cycle R-HSA-1640170
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
Synthesis of DNA R-HSA-69239
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
ABC-family proteins mediated transport R-HSA-382556
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
Degradation of DVL R-HSA-4641258
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
C-type lectin receptors (CLRs) R-HSA-5621481
S Phase R-HSA-69242
Orc1 removal from chromatin R-HSA-68949
Signal Transduction R-HSA-162582
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX1 R-HSA-8878171
Axon guidance R-HSA-422475
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hedgehog ligand biogenesis R-HSA-5358346
Cellular response to chemical stress R-HSA-9711123
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to hypoxia R-HSA-1234174
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by ROBO receptors R-HSA-376176
Mitotic Metaphase and Anaphase R-HSA-2555396
Interleukin-1 family signaling R-HSA-446652
Metabolism of RNA R-HSA-8953854
TCR signaling R-HSA-202403
Developmental Biology R-HSA-1266738
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
HIV Infection R-HSA-162906
PTEN Regulation R-HSA-6807070
DNA Replication R-HSA-69306
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of NF-kappaB in B cells R-HSA-1169091
Hedgehog 'off' state R-HSA-5610787
Generic Transcription Pathway R-HSA-212436
Hh mutants are degraded by ERAD R-HSA-5362768

Expression Atlas ENSG00000222028
NCBI gene (formerly Entrezgene) 122706
GeneCards 31963
HGNC Symbol HGNC:31963
MIM gene 611137
UniProtKB Gene Name A5LHX3
WikiGene 122706
Gene: APEX1
Ensembl ID : ENSG00000100823
Description: apurinic/apyrimidinic endodeoxyribonuclease 1
Gene Synonyms: APE,APE-1,APEN,APEX,APX,HAP1,REF-1,REF1
1 APIs:
214 Possible Orthologues:

DNA Repair R-HSA-73894
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Displacement of DNA glycosylase by APEX1 R-HSA-110357
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Resolution of Abasic Sites (AP sites) R-HSA-73933
Base Excision Repair R-HSA-73884
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930
Resolution of Abasic Sites (AP sites) R-HSA-73933
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381
Displacement of DNA glycosylase by APEX1 R-HSA-110357
Base Excision Repair R-HSA-73884
DNA Repair R-HSA-73894
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801
DNA Repair R-HSA-73894
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381
Resolution of Abasic Sites (AP sites) R-HSA-73933
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Base Excision Repair R-HSA-73884
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930
Displacement of DNA glycosylase by APEX1 R-HSA-110357
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
DNA Repair R-HSA-73894
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Base Excision Repair R-HSA-73884
Displacement of DNA glycosylase by APEX1 R-HSA-110357
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801
Resolution of Abasic Sites (AP sites) R-HSA-73933
Resolution of Abasic Sites (AP sites) R-HSA-73933
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Base Excision Repair R-HSA-73884
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381
DNA Repair R-HSA-73894
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Displacement of DNA glycosylase by APEX1 R-HSA-110357
DNA Repair R-HSA-73894
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Base Excision Repair R-HSA-73884
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801
Displacement of DNA glycosylase by APEX1 R-HSA-110357
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381
Resolution of Abasic Sites (AP sites) R-HSA-73933
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930
Displacement of DNA glycosylase by APEX1 R-HSA-110357
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801
DNA Repair R-HSA-73894
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Resolution of Abasic Sites (AP sites) R-HSA-73933
Base Excision Repair R-HSA-73884
Base Excision Repair R-HSA-73884
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930
DNA Repair R-HSA-73894
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Displacement of DNA glycosylase by APEX1 R-HSA-110357
Resolution of Abasic Sites (AP sites) R-HSA-73933
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Base Excision Repair R-HSA-73884
DNA Repair R-HSA-73894
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801
Resolution of Abasic Sites (AP sites) R-HSA-73933
Displacement of DNA glycosylase by APEX1 R-HSA-110357
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381
DNA Repair R-HSA-73894
Displacement of DNA glycosylase by APEX1 R-HSA-110357
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Base Excision Repair R-HSA-73884
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Resolution of Abasic Sites (AP sites) R-HSA-73933
DNA Repair R-HSA-73894
Resolution of Abasic Sites (AP sites) R-HSA-73933
Base Excision Repair R-HSA-73884
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801
Displacement of DNA glycosylase by APEX1 R-HSA-110357
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362

Expression Atlas ENSG00000100823
NCBI gene (formerly Entrezgene) 328
GeneCards 587
HGNC Symbol HGNC:587
MIM gene 107748
UniProtKB Gene Name Q5TZP7
WikiGene 328
Gene: PDE4A
Ensembl ID : ENSG00000065989
Description: phosphodiesterase 4A
Gene Synonyms: DPDE2
23 APIs:
250 Possible Orthologues:

Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
Opioid Signalling R-HSA-111885
Signaling by GPCR R-HSA-372790
DARPP-32 events R-HSA-180024
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
DARPP-32 events R-HSA-180024
Opioid Signalling R-HSA-111885
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
Opioid Signalling R-HSA-111885
DARPP-32 events R-HSA-180024
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
DARPP-32 events R-HSA-180024
GPCR downstream signalling R-HSA-388396
Opioid Signalling R-HSA-111885
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
DARPP-32 events R-HSA-180024
Opioid Signalling R-HSA-111885
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Opioid Signalling R-HSA-111885
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
DARPP-32 events R-HSA-180024
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
G alpha (i) signalling events R-HSA-418594
DARPP-32 events R-HSA-180024
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Opioid Signalling R-HSA-111885
Opioid Signalling R-HSA-111885
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
DARPP-32 events R-HSA-180024
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
DARPP-32 events R-HSA-180024
Opioid Signalling R-HSA-111885
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594

Expression Atlas ENSG00000065989
NCBI gene (formerly Entrezgene) 5141
GeneCards 8780
HGNC Symbol HGNC:8780
MIM gene 600126
UniProtKB Gene Name P27815
WikiGene 5141
Gene: DPYD
Ensembl ID : ENSG00000188641
Description: dihydropyrimidine dehydrogenase
Gene Synonyms: DHPDHASE,DPD
2 APIs:
223 Possible Orthologues:

Metabolism of nucleotides R-HSA-15869
Pyrimidine catabolism R-HSA-73621
Nucleotide catabolism R-HSA-8956319
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Pyrimidine catabolism R-HSA-73621
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism R-HSA-8956319
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism R-HSA-8956319
Metabolism R-HSA-1430728
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Pyrimidine catabolism R-HSA-73621
Metabolism of nucleotides R-HSA-15869
Pyrimidine catabolism R-HSA-73621
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Pyrimidine catabolism R-HSA-73621
Nucleotide catabolism R-HSA-8956319

Expression Atlas ENSG00000188641
LRG display in Ensembl gene LRG_722
NCBI gene (formerly Entrezgene) 1806
GeneCards 3012
HGNC Symbol HGNC:3012
MIM gene 612779
MIM morbid 274270
UniProtKB Gene Name Q12882
WikiGene 1806