Gene: KIT
Ensembl ID : ENSG00000157404
Description: KIT proto-oncogene, receptor tyrosine kinase
Gene Synonyms: C-KIT,CD117,PBT,SCFR
32 APIs:
211 Possible Orthologues:

Signaling by extracellular domain mutants of KIT R-HSA-9680187
MAPK family signaling cascades R-HSA-5683057
PI3K/AKT Signaling in Cancer R-HSA-2219528
Generic Transcription Pathway R-HSA-212436
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Masitinib-resistant KIT mutants R-HSA-9669924
PIP3 activates AKT signaling R-HSA-1257604
Sorafenib-resistant KIT mutants R-HSA-9669936
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by kinase domain mutants of KIT R-HSA-9669933
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Drug resistance of KIT mutants R-HSA-9669937
Sunitinib-resistant KIT mutants R-HSA-9669934
Signaling by SCF-KIT R-HSA-1433557
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Disease R-HSA-1643685
KIT mutants bind TKIs R-HSA-9669921
RAF/MAP kinase cascade R-HSA-5673001
Dasatinib-resistant KIT mutants R-HSA-9669914
Intracellular signaling by second messengers R-HSA-9006925
Nilotinib-resistant KIT mutants R-HSA-9669926
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Regorafenib-resistant KIT mutants R-HSA-9669929
Regulation of KIT signaling R-HSA-1433559
Negative regulation of the PI3K/AKT network R-HSA-199418
Imatinib-resistant KIT mutants R-HSA-9669917
Signal Transduction R-HSA-162582
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by KIT in disease R-HSA-9669938
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
PI3K/AKT Signaling in Cancer R-HSA-2219528
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
MAPK family signaling cascades R-HSA-5683057
Drug resistance of KIT mutants R-HSA-9669937
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Sorafenib-resistant KIT mutants R-HSA-9669936
Intracellular signaling by second messengers R-HSA-9006925
Regulation of KIT signaling R-HSA-1433559
RNA Polymerase II Transcription R-HSA-73857
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of the PI3K/AKT network R-HSA-199418
Masitinib-resistant KIT mutants R-HSA-9669924
Signaling by SCF-KIT R-HSA-1433557
Signaling by kinase domain mutants of KIT R-HSA-9669933
Regorafenib-resistant KIT mutants R-HSA-9669929
Sunitinib-resistant KIT mutants R-HSA-9669934
Nilotinib-resistant KIT mutants R-HSA-9669926
Disease R-HSA-1643685
Signaling by KIT in disease R-HSA-9669938
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Imatinib-resistant KIT mutants R-HSA-9669917
MAPK1/MAPK3 signaling R-HSA-5684996
PIP3 activates AKT signaling R-HSA-1257604
Generic Transcription Pathway R-HSA-212436
KIT mutants bind TKIs R-HSA-9669921
Gene expression (Transcription) R-HSA-74160
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Dasatinib-resistant KIT mutants R-HSA-9669914
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Signal Transduction R-HSA-162582
Masitinib-resistant KIT mutants R-HSA-9669924
Generic Transcription Pathway R-HSA-212436
Signaling by kinase domain mutants of KIT R-HSA-9669933
PIP3 activates AKT signaling R-HSA-1257604
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Sorafenib-resistant KIT mutants R-HSA-9669936
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by KIT in disease R-HSA-9669938
Signal Transduction R-HSA-162582
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Nilotinib-resistant KIT mutants R-HSA-9669926
Intracellular signaling by second messengers R-HSA-9006925
Gene expression (Transcription) R-HSA-74160
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Dasatinib-resistant KIT mutants R-HSA-9669914
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Regulation of KIT signaling R-HSA-1433559
KIT mutants bind TKIs R-HSA-9669921
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regorafenib-resistant KIT mutants R-HSA-9669929
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Negative regulation of the PI3K/AKT network R-HSA-199418
Drug resistance of KIT mutants R-HSA-9669937
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Imatinib-resistant KIT mutants R-HSA-9669917
Signaling by SCF-KIT R-HSA-1433557
Sunitinib-resistant KIT mutants R-HSA-9669934
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Signaling by SCF-KIT R-HSA-1433557
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Regulation of KIT signaling R-HSA-1433559
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Sunitinib-resistant KIT mutants R-HSA-9669934
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Sorafenib-resistant KIT mutants R-HSA-9669936
MAPK1/MAPK3 signaling R-HSA-5684996
Masitinib-resistant KIT mutants R-HSA-9669924
Gene expression (Transcription) R-HSA-74160
RAF/MAP kinase cascade R-HSA-5673001
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
Dasatinib-resistant KIT mutants R-HSA-9669914
Regorafenib-resistant KIT mutants R-HSA-9669929
Imatinib-resistant KIT mutants R-HSA-9669917
KIT mutants bind TKIs R-HSA-9669921
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nilotinib-resistant KIT mutants R-HSA-9669926
RNA Polymerase II Transcription R-HSA-73857
Signaling by kinase domain mutants of KIT R-HSA-9669933
Drug resistance of KIT mutants R-HSA-9669937
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by KIT in disease R-HSA-9669938
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Drug resistance of KIT mutants R-HSA-9669937
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
KIT mutants bind TKIs R-HSA-9669921
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regorafenib-resistant KIT mutants R-HSA-9669929
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by extracellular domain mutants of KIT R-HSA-9680187
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by KIT in disease R-HSA-9669938
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Sunitinib-resistant KIT mutants R-HSA-9669934
Disease R-HSA-1643685
Nilotinib-resistant KIT mutants R-HSA-9669926
Signal Transduction R-HSA-162582
Sorafenib-resistant KIT mutants R-HSA-9669936
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by SCF-KIT R-HSA-1433557
Regulation of KIT signaling R-HSA-1433559
PIP3 activates AKT signaling R-HSA-1257604
Generic Transcription Pathway R-HSA-212436
RAF/MAP kinase cascade R-HSA-5673001
Imatinib-resistant KIT mutants R-HSA-9669917
Masitinib-resistant KIT mutants R-HSA-9669924
MAPK family signaling cascades R-HSA-5683057
PI3K/AKT Signaling in Cancer R-HSA-2219528
Dasatinib-resistant KIT mutants R-HSA-9669914
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by kinase domain mutants of KIT R-HSA-9669933
Drug resistance of KIT mutants R-HSA-9669937
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Generic Transcription Pathway R-HSA-212436
KIT mutants bind TKIs R-HSA-9669921
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Masitinib-resistant KIT mutants R-HSA-9669924
Nilotinib-resistant KIT mutants R-HSA-9669926
Regulation of KIT signaling R-HSA-1433559
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Imatinib-resistant KIT mutants R-HSA-9669917
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Sorafenib-resistant KIT mutants R-HSA-9669936
Signaling by kinase domain mutants of KIT R-HSA-9669933
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by SCF-KIT R-HSA-1433557
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
Sunitinib-resistant KIT mutants R-HSA-9669934
Regorafenib-resistant KIT mutants R-HSA-9669929
Negative regulation of the PI3K/AKT network R-HSA-199418
Gene expression (Transcription) R-HSA-74160
Dasatinib-resistant KIT mutants R-HSA-9669914
Signaling by KIT in disease R-HSA-9669938
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signal Transduction R-HSA-162582
Imatinib-resistant KIT mutants R-HSA-9669917
Nilotinib-resistant KIT mutants R-HSA-9669926
Signaling by KIT in disease R-HSA-9669938
Sorafenib-resistant KIT mutants R-HSA-9669936
RNA Polymerase II Transcription R-HSA-73857
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
MAPK1/MAPK3 signaling R-HSA-5684996
Gene expression (Transcription) R-HSA-74160
Dasatinib-resistant KIT mutants R-HSA-9669914
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Regorafenib-resistant KIT mutants R-HSA-9669929
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
KIT mutants bind TKIs R-HSA-9669921
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by kinase domain mutants of KIT R-HSA-9669933
Masitinib-resistant KIT mutants R-HSA-9669924
MAPK family signaling cascades R-HSA-5683057
Drug resistance of KIT mutants R-HSA-9669937
Generic Transcription Pathway R-HSA-212436
Sunitinib-resistant KIT mutants R-HSA-9669934
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by SCF-KIT R-HSA-1433557
Regulation of KIT signaling R-HSA-1433559
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Intracellular signaling by second messengers R-HSA-9006925
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Signaling by SCF-KIT R-HSA-1433557
Sorafenib-resistant KIT mutants R-HSA-9669936
MAPK1/MAPK3 signaling R-HSA-5684996
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
RAF/MAP kinase cascade R-HSA-5673001
Regulation of KIT signaling R-HSA-1433559
PIP3 activates AKT signaling R-HSA-1257604
Nilotinib-resistant KIT mutants R-HSA-9669926
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by kinase domain mutants of KIT R-HSA-9669933
Signaling by KIT in disease R-HSA-9669938
Disease R-HSA-1643685
Dasatinib-resistant KIT mutants R-HSA-9669914
Masitinib-resistant KIT mutants R-HSA-9669924
Imatinib-resistant KIT mutants R-HSA-9669917
Sunitinib-resistant KIT mutants R-HSA-9669934
Signaling by extracellular domain mutants of KIT R-HSA-9680187
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Drug resistance of KIT mutants R-HSA-9669937
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Regorafenib-resistant KIT mutants R-HSA-9669929
Negative regulation of the PI3K/AKT network R-HSA-199418
KIT mutants bind TKIs R-HSA-9669921
Gene expression (Transcription) R-HSA-74160
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Regulation of KIT signaling R-HSA-1433559
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
KIT mutants bind TKIs R-HSA-9669921
Sorafenib-resistant KIT mutants R-HSA-9669936
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by kinase domain mutants of KIT R-HSA-9669933
Nilotinib-resistant KIT mutants R-HSA-9669926
Regorafenib-resistant KIT mutants R-HSA-9669929
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RNA Polymerase II Transcription R-HSA-73857
Signaling by SCF-KIT R-HSA-1433557
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Masitinib-resistant KIT mutants R-HSA-9669924
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by KIT in disease R-HSA-9669938
Dasatinib-resistant KIT mutants R-HSA-9669914
Imatinib-resistant KIT mutants R-HSA-9669917
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
PI3K/AKT Signaling in Cancer R-HSA-2219528
Drug resistance of KIT mutants R-HSA-9669937
Sunitinib-resistant KIT mutants R-HSA-9669934
Disease R-HSA-1643685
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of the PI3K/AKT network R-HSA-199418
Masitinib-resistant KIT mutants R-HSA-9669924
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Nilotinib-resistant KIT mutants R-HSA-9669926
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Imatinib-resistant KIT mutants R-HSA-9669917
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Drug resistance of KIT mutants R-HSA-9669937
Signaling by SCF-KIT R-HSA-1433557
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by KIT in disease R-HSA-9669938
Dasatinib-resistant KIT mutants R-HSA-9669914
Signaling by kinase domain mutants of KIT R-HSA-9669933
PI3K/AKT Signaling in Cancer R-HSA-2219528
Disease R-HSA-1643685
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Regulation of KIT signaling R-HSA-1433559
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Sunitinib-resistant KIT mutants R-HSA-9669934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Regorafenib-resistant KIT mutants R-HSA-9669929
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
Sorafenib-resistant KIT mutants R-HSA-9669936
Negative regulation of the PI3K/AKT network R-HSA-199418
KIT mutants bind TKIs R-HSA-9669921
Signaling by Receptor Tyrosine Kinases R-HSA-9006934

Expression Atlas ENSG00000157404
LRG display in Ensembl gene LRG_307
NCBI gene (formerly Entrezgene) 3815
GeneCards 6342
HGNC Symbol HGNC:6342
MIM gene 164920
MIM morbid 606764
UniProtKB Gene Name P10721
WikiGene 3815
Gene: PDGFRB
Ensembl ID : ENSG00000113721
Description: platelet derived growth factor receptor beta
Gene Synonyms: CD140B,JTK12,PDGFR,PDGFR1
40 APIs:
247 Possible Orthologues:

Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Downstream signal transduction R-HSA-186763
Signaling by PDGF R-HSA-186797
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAF/MAP kinase cascade R-HSA-5673001
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by PDGF R-HSA-186797
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Downstream signal transduction R-HSA-186763
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Downstream signal transduction R-HSA-186763
MAPK family signaling cascades R-HSA-5683057
Signaling by PDGF R-HSA-186797
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Negative regulation of the PI3K/AKT network R-HSA-199418
PIP3 activates AKT signaling R-HSA-1257604
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
MAPK1/MAPK3 signaling R-HSA-5684996
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGF R-HSA-186797
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signal transduction R-HSA-186763
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by PDGF R-HSA-186797
Downstream signal transduction R-HSA-186763
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
Downstream signal transduction R-HSA-186763
Disease R-HSA-1643685
Signaling by PDGF R-HSA-186797
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by PDGF R-HSA-186797
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Downstream signal transduction R-HSA-186763
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF/MAP kinase cascade R-HSA-5673001
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by PDGF R-HSA-186797
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Intracellular signaling by second messengers R-HSA-9006925
Downstream signal transduction R-HSA-186763
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Signaling by PDGF R-HSA-186797
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signal transduction R-HSA-186763
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RAF/MAP kinase cascade R-HSA-5673001
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK family signaling cascades R-HSA-5683057
Signaling by PDGF R-HSA-186797
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signal transduction R-HSA-186763
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604

Expression Atlas ENSG00000113721
NCBI gene (formerly Entrezgene) 5159
GeneCards 8804
HGNC Symbol HGNC:8804
MIM gene 173410
MIM morbid 616592
UniProtKB Gene Name P09619
WikiGene 5159
Gene: FLT3
Ensembl ID : ENSG00000122025
Description: fms related receptor tyrosine kinase 3
Gene Synonyms: CD135,FLK2,STK1
41 APIs:
134 Possible Orthologues:

tamatinib-resistant FLT3 mutants R-HSA-9703009
Immune System R-HSA-168256
STAT5 Activation R-HSA-9645135
Insulin receptor signalling cascade R-HSA-74751
gilteritinib-resistant FLT3 mutants R-HSA-9702590
IRS-related events triggered by IGF1R R-HSA-2428928
IRS-mediated signalling R-HSA-112399
FLT3 Signaling R-HSA-9607240
quizartinib-resistant FLT3 mutants R-HSA-9702620
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Insulin receptor R-HSA-74752
ponatinib-resistant FLT3 mutants R-HSA-9702614
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
crenolanib-resistant FLT3 mutants R-HSA-9702581
Negative regulation of the PI3K/AKT network R-HSA-199418
FLT3 signaling by CBL mutants R-HSA-9706377
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
sorafenib-resistant FLT3 mutants R-HSA-9702624
Drug resistance of FLT3 mutants R-HSA-9702506
linifanib-resistant FLT3 mutants R-HSA-9702998
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
tamatinib-resistant FLT3 mutants R-HSA-9703009
PI3K/AKT Signaling in Cancer R-HSA-2219528
semaxanib-resistant FLT3 mutants R-HSA-9702577
sunitinib-resistant FLT3 mutants R-HSA-9702632
Disease R-HSA-1643685
FLT3 mutants bind TKIs R-HSA-9702509
FLT3 signaling through SRC family kinases R-HSA-9706374
FLT3 signaling in disease R-HSA-9682385
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IGF1R signaling cascade R-HSA-2428924
pexidartinib-resistant FLT3 mutants R-HSA-9702605
Signal Transduction R-HSA-162582
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
KW2449-resistant FLT3 mutants R-HSA-9702569
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
tandutinib-resistant FLT3 mutants R-HSA-9702636
Cytokine Signaling in Immune system R-HSA-1280215
MAPK family signaling cascades R-HSA-5683057
Negative regulation of FLT3 R-HSA-9706369
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
midostaurin-resistant FLT3 mutants R-HSA-9702600
PI3K Cascade R-HSA-109704
MAPK1/MAPK3 signaling R-HSA-5684996
Insulin receptor signalling cascade R-HSA-74751
linifanib-resistant FLT3 mutants R-HSA-9702998
PIP3 activates AKT signaling R-HSA-1257604
quizartinib-resistant FLT3 mutants R-HSA-9702620
tamatinib-resistant FLT3 mutants R-HSA-9703009
tandutinib-resistant FLT3 mutants R-HSA-9702636
PI3K/AKT Signaling in Cancer R-HSA-2219528
Immune System R-HSA-168256
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Signal Transduction R-HSA-162582
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS-related events triggered by IGF1R R-HSA-2428928
KW2449-resistant FLT3 mutants R-HSA-9702569
MAPK family signaling cascades R-HSA-5683057
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FLT3 mutants bind TKIs R-HSA-9702509
PI3K Cascade R-HSA-109704
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Insulin receptor R-HSA-74752
IRS-mediated signalling R-HSA-112399
gilteritinib-resistant FLT3 mutants R-HSA-9702590
IGF1R signaling cascade R-HSA-2428924
sunitinib-resistant FLT3 mutants R-HSA-9702632
Negative regulation of FLT3 R-HSA-9706369
FLT3 Signaling R-HSA-9607240
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Drug resistance of FLT3 mutants R-HSA-9702506
FLT3 signaling by CBL mutants R-HSA-9706377
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
FLT3 signaling in disease R-HSA-9682385
sorafenib-resistant FLT3 mutants R-HSA-9702624
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
pexidartinib-resistant FLT3 mutants R-HSA-9702605
crenolanib-resistant FLT3 mutants R-HSA-9702581
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Intracellular signaling by second messengers R-HSA-9006925
FLT3 signaling through SRC family kinases R-HSA-9706374
STAT5 Activation R-HSA-9645135
MAPK1/MAPK3 signaling R-HSA-5684996
midostaurin-resistant FLT3 mutants R-HSA-9702600
semaxanib-resistant FLT3 mutants R-HSA-9702577
ponatinib-resistant FLT3 mutants R-HSA-9702614
FLT3 signaling by CBL mutants R-HSA-9706377
Cytokine Signaling in Immune system R-HSA-1280215
IRS-mediated signalling R-HSA-112399
FLT3 signaling in disease R-HSA-9682385
gilteritinib-resistant FLT3 mutants R-HSA-9702590
FLT3 signaling through SRC family kinases R-HSA-9706374
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
midostaurin-resistant FLT3 mutants R-HSA-9702600
IRS-related events triggered by IGF1R R-HSA-2428928
ponatinib-resistant FLT3 mutants R-HSA-9702614
Insulin receptor signalling cascade R-HSA-74751
FLT3 mutants bind TKIs R-HSA-9702509
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
crenolanib-resistant FLT3 mutants R-HSA-9702581
IGF1R signaling cascade R-HSA-2428924
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
sorafenib-resistant FLT3 mutants R-HSA-9702624
Negative regulation of the PI3K/AKT network R-HSA-199418
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Insulin receptor R-HSA-74752
Immune System R-HSA-168256
linifanib-resistant FLT3 mutants R-HSA-9702998
FLT3 Signaling R-HSA-9607240
sunitinib-resistant FLT3 mutants R-HSA-9702632
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
PI3K Cascade R-HSA-109704
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
MAPK family signaling cascades R-HSA-5683057
pexidartinib-resistant FLT3 mutants R-HSA-9702605
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Disease R-HSA-1643685
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
STAT5 Activation R-HSA-9645135
KW2449-resistant FLT3 mutants R-HSA-9702569
Negative regulation of FLT3 R-HSA-9706369
Drug resistance of FLT3 mutants R-HSA-9702506
PIP3 activates AKT signaling R-HSA-1257604
quizartinib-resistant FLT3 mutants R-HSA-9702620
tandutinib-resistant FLT3 mutants R-HSA-9702636
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
tamatinib-resistant FLT3 mutants R-HSA-9703009
semaxanib-resistant FLT3 mutants R-HSA-9702577
crenolanib-resistant FLT3 mutants R-HSA-9702581
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
RAF/MAP kinase cascade R-HSA-5673001
FLT3 Signaling R-HSA-9607240
linifanib-resistant FLT3 mutants R-HSA-9702998
Negative regulation of FLT3 R-HSA-9706369
gilteritinib-resistant FLT3 mutants R-HSA-9702590
MAPK1/MAPK3 signaling R-HSA-5684996
KW2449-resistant FLT3 mutants R-HSA-9702569
ponatinib-resistant FLT3 mutants R-HSA-9702614
FLT3 mutants bind TKIs R-HSA-9702509
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Drug resistance of FLT3 mutants R-HSA-9702506
FLT3 signaling through SRC family kinases R-HSA-9706374
midostaurin-resistant FLT3 mutants R-HSA-9702600
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
quizartinib-resistant FLT3 mutants R-HSA-9702620
Intracellular signaling by second messengers R-HSA-9006925
semaxanib-resistant FLT3 mutants R-HSA-9702577
PIP3 activates AKT signaling R-HSA-1257604
sorafenib-resistant FLT3 mutants R-HSA-9702624
FLT3 signaling in disease R-HSA-9682385
STAT5 Activation R-HSA-9645135
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
tandutinib-resistant FLT3 mutants R-HSA-9702636
sunitinib-resistant FLT3 mutants R-HSA-9702632
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IRS-mediated signalling R-HSA-112399
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Insulin receptor R-HSA-74752
IGF1R signaling cascade R-HSA-2428924
PI3K Cascade R-HSA-109704
MAPK family signaling cascades R-HSA-5683057
Insulin receptor signalling cascade R-HSA-74751
tamatinib-resistant FLT3 mutants R-HSA-9703009
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
PI3K/AKT Signaling in Cancer R-HSA-2219528
FLT3 signaling by CBL mutants R-HSA-9706377
pexidartinib-resistant FLT3 mutants R-HSA-9702605
Disease R-HSA-1643685
Negative regulation of the PI3K/AKT network R-HSA-199418
quizartinib-resistant FLT3 mutants R-HSA-9702620
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K/AKT Signaling in Cancer R-HSA-2219528
IRS-mediated signalling R-HSA-112399
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS-related events triggered by IGF1R R-HSA-2428928
sorafenib-resistant FLT3 mutants R-HSA-9702624
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
FLT3 Signaling R-HSA-9607240
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
crenolanib-resistant FLT3 mutants R-HSA-9702581
Insulin receptor signalling cascade R-HSA-74751
Negative regulation of the PI3K/AKT network R-HSA-199418
pexidartinib-resistant FLT3 mutants R-HSA-9702605
tamatinib-resistant FLT3 mutants R-HSA-9703009
Negative regulation of FLT3 R-HSA-9706369
MAPK1/MAPK3 signaling R-HSA-5684996
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
FLT3 signaling in disease R-HSA-9682385
gilteritinib-resistant FLT3 mutants R-HSA-9702590
PI3K Cascade R-HSA-109704
Disease R-HSA-1643685
KW2449-resistant FLT3 mutants R-HSA-9702569
MAPK family signaling cascades R-HSA-5683057
ponatinib-resistant FLT3 mutants R-HSA-9702614
Immune System R-HSA-168256
midostaurin-resistant FLT3 mutants R-HSA-9702600
semaxanib-resistant FLT3 mutants R-HSA-9702577
STAT5 Activation R-HSA-9645135
PIP3 activates AKT signaling R-HSA-1257604
Drug resistance of FLT3 mutants R-HSA-9702506
Signaling by Insulin receptor R-HSA-74752
IGF1R signaling cascade R-HSA-2428924
linifanib-resistant FLT3 mutants R-HSA-9702998
FLT3 signaling by CBL mutants R-HSA-9706377
tandutinib-resistant FLT3 mutants R-HSA-9702636
sunitinib-resistant FLT3 mutants R-HSA-9702632
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FLT3 mutants bind TKIs R-HSA-9702509
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Intracellular signaling by second messengers R-HSA-9006925
FLT3 signaling through SRC family kinases R-HSA-9706374
Drug resistance of FLT3 mutants R-HSA-9702506
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
IRS-related events triggered by IGF1R R-HSA-2428928
FLT3 signaling by CBL mutants R-HSA-9706377
pexidartinib-resistant FLT3 mutants R-HSA-9702605
sorafenib-resistant FLT3 mutants R-HSA-9702624
gilteritinib-resistant FLT3 mutants R-HSA-9702590
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
linifanib-resistant FLT3 mutants R-HSA-9702998
FLT3 signaling through SRC family kinases R-HSA-9706374
quizartinib-resistant FLT3 mutants R-HSA-9702620
RAF/MAP kinase cascade R-HSA-5673001
Intracellular signaling by second messengers R-HSA-9006925
sunitinib-resistant FLT3 mutants R-HSA-9702632
MAPK family signaling cascades R-HSA-5683057
IGF1R signaling cascade R-HSA-2428924
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of FLT3 R-HSA-9706369
Signal Transduction R-HSA-162582
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
crenolanib-resistant FLT3 mutants R-HSA-9702581
PI3K/AKT Signaling in Cancer R-HSA-2219528
Insulin receptor signalling cascade R-HSA-74751
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
FLT3 mutants bind TKIs R-HSA-9702509
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Insulin receptor R-HSA-74752
semaxanib-resistant FLT3 mutants R-HSA-9702577
tandutinib-resistant FLT3 mutants R-HSA-9702636
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
tamatinib-resistant FLT3 mutants R-HSA-9703009
FLT3 signaling in disease R-HSA-9682385
KW2449-resistant FLT3 mutants R-HSA-9702569
midostaurin-resistant FLT3 mutants R-HSA-9702600
ponatinib-resistant FLT3 mutants R-HSA-9702614
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
STAT5 Activation R-HSA-9645135
FLT3 Signaling R-HSA-9607240
IRS-mediated signalling R-HSA-112399
PI3K Cascade R-HSA-109704
crenolanib-resistant FLT3 mutants R-HSA-9702581
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
STAT5 Activation R-HSA-9645135
tandutinib-resistant FLT3 mutants R-HSA-9702636
Signaling by Insulin receptor R-HSA-74752
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
IGF1R signaling cascade R-HSA-2428924
Drug resistance of FLT3 mutants R-HSA-9702506
RAF/MAP kinase cascade R-HSA-5673001
PI3K/AKT Signaling in Cancer R-HSA-2219528
IRS-related events triggered by IGF1R R-HSA-2428928
Intracellular signaling by second messengers R-HSA-9006925
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Insulin receptor signalling cascade R-HSA-74751
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FLT3 signaling through SRC family kinases R-HSA-9706374
sorafenib-resistant FLT3 mutants R-HSA-9702624
gilteritinib-resistant FLT3 mutants R-HSA-9702590
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
IRS-mediated signalling R-HSA-112399
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K Cascade R-HSA-109704
FLT3 signaling by CBL mutants R-HSA-9706377
Negative regulation of the PI3K/AKT network R-HSA-199418
KW2449-resistant FLT3 mutants R-HSA-9702569
linifanib-resistant FLT3 mutants R-HSA-9702998
semaxanib-resistant FLT3 mutants R-HSA-9702577
FLT3 signaling in disease R-HSA-9682385
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
pexidartinib-resistant FLT3 mutants R-HSA-9702605
tamatinib-resistant FLT3 mutants R-HSA-9703009
sunitinib-resistant FLT3 mutants R-HSA-9702632
FLT3 Signaling R-HSA-9607240
FLT3 mutants bind TKIs R-HSA-9702509
Disease R-HSA-1643685
Negative regulation of FLT3 R-HSA-9706369
quizartinib-resistant FLT3 mutants R-HSA-9702620
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
ponatinib-resistant FLT3 mutants R-HSA-9702614
PIP3 activates AKT signaling R-HSA-1257604
midostaurin-resistant FLT3 mutants R-HSA-9702600
Immune System R-HSA-168256
crenolanib-resistant FLT3 mutants R-HSA-9702581
FLT3 signaling through SRC family kinases R-HSA-9706374
Signaling by Insulin receptor R-HSA-74752
tandutinib-resistant FLT3 mutants R-HSA-9702636
IRS-related events triggered by IGF1R R-HSA-2428928
quizartinib-resistant FLT3 mutants R-HSA-9702620
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
FLT3 signaling in disease R-HSA-9682385
PI3K Cascade R-HSA-109704
IRS-mediated signalling R-HSA-112399
sunitinib-resistant FLT3 mutants R-HSA-9702632
Intracellular signaling by second messengers R-HSA-9006925
FLT3 mutants bind TKIs R-HSA-9702509
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
gilteritinib-resistant FLT3 mutants R-HSA-9702590
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
FLT3 Signaling R-HSA-9607240
KW2449-resistant FLT3 mutants R-HSA-9702569
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
linifanib-resistant FLT3 mutants R-HSA-9702998
Drug resistance of FLT3 mutants R-HSA-9702506
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Immune System R-HSA-168256
sorafenib-resistant FLT3 mutants R-HSA-9702624
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
semaxanib-resistant FLT3 mutants R-HSA-9702577
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
midostaurin-resistant FLT3 mutants R-HSA-9702600
MAPK1/MAPK3 signaling R-HSA-5684996
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
pexidartinib-resistant FLT3 mutants R-HSA-9702605
ponatinib-resistant FLT3 mutants R-HSA-9702614
FLT3 signaling by CBL mutants R-HSA-9706377
STAT5 Activation R-HSA-9645135
Negative regulation of FLT3 R-HSA-9706369
Disease R-HSA-1643685
Insulin receptor signalling cascade R-HSA-74751
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
IGF1R signaling cascade R-HSA-2428924
Drug resistance of FLT3 mutants R-HSA-9702506
FLT3 signaling by CBL mutants R-HSA-9706377
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
FLT3 Signaling R-HSA-9607240
FLT3 mutants bind TKIs R-HSA-9702509
Negative regulation of the PI3K/AKT network R-HSA-199418
tandutinib-resistant FLT3 mutants R-HSA-9702636
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
gilteritinib-resistant FLT3 mutants R-HSA-9702590
tamatinib-resistant FLT3 mutants R-HSA-9703009
crenolanib-resistant FLT3 mutants R-HSA-9702581
Immune System R-HSA-168256
FLT3 signaling in disease R-HSA-9682385
linifanib-resistant FLT3 mutants R-HSA-9702998
Disease R-HSA-1643685
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PIP3 activates AKT signaling R-HSA-1257604
FLT3 signaling through SRC family kinases R-HSA-9706374
Negative regulation of FLT3 R-HSA-9706369
midostaurin-resistant FLT3 mutants R-HSA-9702600
PI3K Cascade R-HSA-109704
sunitinib-resistant FLT3 mutants R-HSA-9702632
STAT5 Activation R-HSA-9645135
RAF/MAP kinase cascade R-HSA-5673001
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Signaling by Insulin receptor R-HSA-74752
MAPK1/MAPK3 signaling R-HSA-5684996
quizartinib-resistant FLT3 mutants R-HSA-9702620
ponatinib-resistant FLT3 mutants R-HSA-9702614
IRS-related events triggered by IGF1R R-HSA-2428928
Signal Transduction R-HSA-162582
sorafenib-resistant FLT3 mutants R-HSA-9702624
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
pexidartinib-resistant FLT3 mutants R-HSA-9702605
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
semaxanib-resistant FLT3 mutants R-HSA-9702577
IGF1R signaling cascade R-HSA-2428924
MAPK family signaling cascades R-HSA-5683057
KW2449-resistant FLT3 mutants R-HSA-9702569
IRS-mediated signalling R-HSA-112399
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
lestaurtinib-resistant FLT3 mutants R-HSA-9702596
Insulin receptor signalling cascade R-HSA-74751
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Insulin receptor R-HSA-74752
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
midostaurin-resistant FLT3 mutants R-HSA-9702600
FLT3 signaling through SRC family kinases R-HSA-9706374
FLT3 Signaling R-HSA-9607240
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
PI3K/AKT Signaling in Cancer R-HSA-2219528
Negative regulation of FLT3 R-HSA-9706369
Drug resistance of FLT3 mutants R-HSA-9702506
sorafenib-resistant FLT3 mutants R-HSA-9702624
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IRS-related events triggered by IGF1R R-HSA-2428928
FLT3 mutants bind TKIs R-HSA-9702509
IRS-mediated signalling R-HSA-112399
pexidartinib-resistant FLT3 mutants R-HSA-9702605
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
quizartinib-resistant FLT3 mutants R-HSA-9702620
semaxanib-resistant FLT3 mutants R-HSA-9702577
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
gilteritinib-resistant FLT3 mutants R-HSA-9702590
MAPK family signaling cascades R-HSA-5683057
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
FLT3 signaling by CBL mutants R-HSA-9706377
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
sunitinib-resistant FLT3 mutants R-HSA-9702632
STAT5 Activation R-HSA-9645135
tamatinib-resistant FLT3 mutants R-HSA-9703009
IGF1R signaling cascade R-HSA-2428924
Insulin receptor signalling cascade R-HSA-74751
ponatinib-resistant FLT3 mutants R-HSA-9702614
Signal Transduction R-HSA-162582
PI3K Cascade R-HSA-109704
linifanib-resistant FLT3 mutants R-HSA-9702998
tandutinib-resistant FLT3 mutants R-HSA-9702636
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PIP3 activates AKT signaling R-HSA-1257604
KW2449-resistant FLT3 mutants R-HSA-9702569
FLT3 signaling in disease R-HSA-9682385
crenolanib-resistant FLT3 mutants R-HSA-9702581
Disease R-HSA-1643685
lestaurtinib-resistant FLT3 mutants R-HSA-9702596

Expression Atlas ENSG00000122025
LRG display in Ensembl gene LRG_457
NCBI gene (formerly Entrezgene) 2322
GeneCards 3765
HGNC Symbol HGNC:3765
MIM gene 136351
MIM morbid 613065
UniProtKB Gene Name P36888
WikiGene 2322
Gene: CSF1R
Ensembl ID : ENSG00000182578
Description: colony stimulating factor 1 receptor
Gene Synonyms: C-FMS,CD115,CSFR,FMS
18 APIs:
273 Possible Orthologues:

RNA Polymerase II Transcription R-HSA-73857
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by Interleukins R-HSA-449147
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by VENTX R-HSA-8853884
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
Other interleukin signaling R-HSA-449836
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by VENTX R-HSA-8853884
Immune System R-HSA-168256
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
RNA Polymerase II Transcription R-HSA-73857
Signaling by Interleukins R-HSA-449147
Other interleukin signaling R-HSA-449836
Cytokine Signaling in Immune system R-HSA-1280215
Other interleukin signaling R-HSA-449836
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by VENTX R-HSA-8853884
Immune System R-HSA-168256
Cytokine Signaling in Immune system R-HSA-1280215
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
RNA Polymerase II Transcription R-HSA-73857
Other interleukin signaling R-HSA-449836
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Signaling by Interleukins R-HSA-449147
Transcriptional Regulation by VENTX R-HSA-8853884
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Other interleukin signaling R-HSA-449836
Transcriptional Regulation by VENTX R-HSA-8853884
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Other interleukin signaling R-HSA-449836
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256
Transcriptional Regulation by VENTX R-HSA-8853884
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional Regulation by VENTX R-HSA-8853884
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
RNA Polymerase II Transcription R-HSA-73857
Signaling by Interleukins R-HSA-449147
Other interleukin signaling R-HSA-449836
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Immune System R-HSA-168256
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Transcriptional Regulation by VENTX R-HSA-8853884
Signaling by Interleukins R-HSA-449147
Gene expression (Transcription) R-HSA-74160
Cytokine Signaling in Immune system R-HSA-1280215
Other interleukin signaling R-HSA-449836
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
RNA Polymerase II Transcription R-HSA-73857
Cytokine Signaling in Immune system R-HSA-1280215
Gene expression (Transcription) R-HSA-74160
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Other interleukin signaling R-HSA-449836
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Transcriptional Regulation by VENTX R-HSA-8853884
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Other interleukin signaling R-HSA-449836
Transcriptional Regulation by VENTX R-HSA-8853884
Gene expression (Transcription) R-HSA-74160
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350

Expression Atlas ENSG00000182578
NCBI gene (formerly Entrezgene) 1436
GeneCards 2433
HGNC Symbol HGNC:2433
MIM gene 164770
MIM morbid 618476
UniProtKB Gene Name P07333
WikiGene 1436
Gene: PDGFRA
Ensembl ID : ENSG00000134853
Description: platelet derived growth factor receptor alpha
Gene Synonyms: CD140A,GAS9,PDGFR2
29 APIs:
204 Possible Orthologues:

RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by PDGF R-HSA-186797
PI3K/AKT Signaling in Cancer R-HSA-2219528
Sunitinib-resistant PDGFR mutants R-HSA-9674401
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Imatinib-resistant PDGFR mutants R-HSA-9674396
Drug resistance of PDGFR mutants R-HSA-9674415
MAPK family signaling cascades R-HSA-5683057
PDGFR mutants bind TKIs R-HSA-9674428
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signal transduction R-HSA-186763
Signaling by PDGFR in disease R-HSA-9671555
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Intracellular signaling by second messengers R-HSA-9006925
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Downstream signal transduction R-HSA-186763
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Sunitinib-resistant PDGFR mutants R-HSA-9674401
RAF/MAP kinase cascade R-HSA-5673001
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Regorafenib-resistant PDGFR mutants R-HSA-9674403
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
Disease R-HSA-1643685
PDGFR mutants bind TKIs R-HSA-9674428
Imatinib-resistant PDGFR mutants R-HSA-9674396
PIP3 activates AKT signaling R-HSA-1257604
Signaling by PDGFR in disease R-HSA-9671555
Drug resistance of PDGFR mutants R-HSA-9674415
Signaling by PDGF R-HSA-186797
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
PI3K/AKT Signaling in Cancer R-HSA-2219528
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Signaling by PDGF R-HSA-186797
Signaling by PDGFR in disease R-HSA-9671555
Downstream signal transduction R-HSA-186763
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK family signaling cascades R-HSA-5683057
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Negative regulation of the PI3K/AKT network R-HSA-199418
Imatinib-resistant PDGFR mutants R-HSA-9674396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PDGFR mutants bind TKIs R-HSA-9674428
Disease R-HSA-1643685
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Drug resistance of PDGFR mutants R-HSA-9674415
Imatinib-resistant PDGFR mutants R-HSA-9674396
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Drug resistance of PDGFR mutants R-HSA-9674415
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by PDGFR in disease R-HSA-9671555
PDGFR mutants bind TKIs R-HSA-9674428
Disease R-HSA-1643685
Signaling by PDGF R-HSA-186797
Sorafenib-resistant PDGFR mutants R-HSA-9674404
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
Downstream signal transduction R-HSA-186763
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signal transduction R-HSA-186763
Signaling by PDGF R-HSA-186797
Signaling by PDGFR in disease R-HSA-9671555
RAF/MAP kinase cascade R-HSA-5673001
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Disease R-HSA-1643685
PDGFR mutants bind TKIs R-HSA-9674428
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal Transduction R-HSA-162582
Drug resistance of PDGFR mutants R-HSA-9674415
Imatinib-resistant PDGFR mutants R-HSA-9674396
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regorafenib-resistant PDGFR mutants R-HSA-9674403
MAPK family signaling cascades R-HSA-5683057
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PIP3 activates AKT signaling R-HSA-1257604
Signaling by PDGFR in disease R-HSA-9671555
Downstream signal transduction R-HSA-186763
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
Imatinib-resistant PDGFR mutants R-HSA-9674396
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
PDGFR mutants bind TKIs R-HSA-9674428
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by PDGF R-HSA-186797
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
PIP3 activates AKT signaling R-HSA-1257604
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
MAPK1/MAPK3 signaling R-HSA-5684996
Drug resistance of PDGFR mutants R-HSA-9674415
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGFR in disease R-HSA-9671555
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
PDGFR mutants bind TKIs R-HSA-9674428
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signal transduction R-HSA-186763
Drug resistance of PDGFR mutants R-HSA-9674415
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Imatinib-resistant PDGFR mutants R-HSA-9674396
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by PDGF R-HSA-186797
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGF R-HSA-186797
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Disease R-HSA-1643685
Drug resistance of PDGFR mutants R-HSA-9674415
PDGFR mutants bind TKIs R-HSA-9674428
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Downstream signal transduction R-HSA-186763
PIP3 activates AKT signaling R-HSA-1257604
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Imatinib-resistant PDGFR mutants R-HSA-9674396
MAPK family signaling cascades R-HSA-5683057
Signaling by PDGFR in disease R-HSA-9671555
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signal transduction R-HSA-186763
Sunitinib-resistant PDGFR mutants R-HSA-9674401
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK family signaling cascades R-HSA-5683057
Drug resistance of PDGFR mutants R-HSA-9674415
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Imatinib-resistant PDGFR mutants R-HSA-9674396
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
PDGFR mutants bind TKIs R-HSA-9674428
Signaling by PDGFR in disease R-HSA-9671555
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regorafenib-resistant PDGFR mutants R-HSA-9674403
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Signaling by PDGF R-HSA-186797
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAF/MAP kinase cascade R-HSA-5673001
Drug resistance of PDGFR mutants R-HSA-9674415
PDGFR mutants bind TKIs R-HSA-9674428
MAPK1/MAPK3 signaling R-HSA-5684996
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Downstream signal transduction R-HSA-186763
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Sunitinib-resistant PDGFR mutants R-HSA-9674401
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Imatinib-resistant PDGFR mutants R-HSA-9674396
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signal Transduction R-HSA-162582
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by PDGF R-HSA-186797
MAPK family signaling cascades R-HSA-5683057
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by PDGFR in disease R-HSA-9671555
Negative regulation of the PI3K/AKT network R-HSA-199418

Expression Atlas ENSG00000134853
LRG display in Ensembl gene LRG_309
NCBI gene (formerly Entrezgene) 5156
GeneCards 8803
HGNC Symbol HGNC:8803
MIM gene 173490
MIM morbid 607685
UniProtKB Gene Name P16234
WikiGene 5156
Gene: CCDC6
Ensembl ID : ENSG00000108091
Description: coiled-coil domain containing 6
Gene Synonyms: D10S170,H4,PTC,PTC1,TPC,TST1
2 APIs:
223 Possible Orthologues:

Expression Atlas ENSG00000108091
NCBI gene (formerly Entrezgene) 8030
GeneCards 18782
HGNC Symbol HGNC:18782
MIM gene 601985
UniProtKB Gene Name Q16204
WikiGene 8030
Gene: KIF5B
Ensembl ID : ENSG00000170759
Description: kinesin family member 5B
Gene Synonyms: KNS,KNS1,UKHC
2 APIs:
288 Possible Orthologues:

Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Hemostasis R-HSA-109582
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
MHC class II antigen presentation R-HSA-2132295
Adaptive Immune System R-HSA-1280218
Factors involved in megakaryocyte development and platelet production R-HSA-983231
RHO GTPase Effectors R-HSA-195258
Metabolism of proteins R-HSA-392499
Membrane Trafficking R-HSA-199991
Kinesins R-HSA-983189
Vesicle-mediated transport R-HSA-5653656
Immune System R-HSA-168256
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Insulin processing R-HSA-264876
Peptide hormone metabolism R-HSA-2980736
RHO GTPases activate KTN1 R-HSA-5625970
Signaling by ALK in cancer R-HSA-9700206
Signaling by Rho GTPases R-HSA-194315
Golgi-to-ER retrograde transport R-HSA-8856688
Disease R-HSA-1643685
Hemostasis R-HSA-109582
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Signaling by ALK in cancer R-HSA-9700206
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Peptide hormone metabolism R-HSA-2980736
Disease R-HSA-1643685
Kinesins R-HSA-983189
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Signaling by Rho GTPases R-HSA-194315
Metabolism of proteins R-HSA-392499
Golgi-to-ER retrograde transport R-HSA-8856688
Vesicle-mediated transport R-HSA-5653656
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Membrane Trafficking R-HSA-199991
MHC class II antigen presentation R-HSA-2132295
Insulin processing R-HSA-264876
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPases activate KTN1 R-HSA-5625970
RHO GTPase Effectors R-HSA-195258
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Immune System R-HSA-168256
Signaling by Rho GTPases R-HSA-194315
RHO GTPase Effectors R-HSA-195258
RHO GTPases activate KTN1 R-HSA-5625970
Disease R-HSA-1643685
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
MHC class II antigen presentation R-HSA-2132295
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Membrane Trafficking R-HSA-199991
Signaling by ALK in cancer R-HSA-9700206
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Kinesins R-HSA-983189
Vesicle-mediated transport R-HSA-5653656
Golgi-to-ER retrograde transport R-HSA-8856688
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Insulin processing R-HSA-264876
Hemostasis R-HSA-109582
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Immune System R-HSA-168256
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Insulin processing R-HSA-264876
Disease R-HSA-1643685
MHC class II antigen presentation R-HSA-2132295
Golgi-to-ER retrograde transport R-HSA-8856688
Adaptive Immune System R-HSA-1280218
RHO GTPases activate KTN1 R-HSA-5625970
Hemostasis R-HSA-109582
Vesicle-mediated transport R-HSA-5653656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signal Transduction R-HSA-162582
Kinesins R-HSA-983189
Signaling by Rho GTPases R-HSA-194315
Metabolism of proteins R-HSA-392499
Signaling by ALK in cancer R-HSA-9700206
Membrane Trafficking R-HSA-199991
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RHO GTPase Effectors R-HSA-195258
Peptide hormone metabolism R-HSA-2980736
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Hemostasis R-HSA-109582
Kinesins R-HSA-983189
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signal Transduction R-HSA-162582
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Golgi-to-ER retrograde transport R-HSA-8856688
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
MHC class II antigen presentation R-HSA-2132295
Immune System R-HSA-168256
Metabolism of proteins R-HSA-392499
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Membrane Trafficking R-HSA-199991
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Insulin processing R-HSA-264876
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
Signaling by Rho GTPases R-HSA-194315
RHO GTPases activate KTN1 R-HSA-5625970
Vesicle-mediated transport R-HSA-5653656
Disease R-HSA-1643685
Peptide hormone metabolism R-HSA-2980736
Signaling by ALK in cancer R-HSA-9700206
RHO GTPase Effectors R-HSA-195258
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Membrane Trafficking R-HSA-199991
Adaptive Immune System R-HSA-1280218
RHO GTPase Effectors R-HSA-195258
Signaling by Rho GTPases R-HSA-194315
MHC class II antigen presentation R-HSA-2132295
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Peptide hormone metabolism R-HSA-2980736
Golgi-to-ER retrograde transport R-HSA-8856688
Signal Transduction R-HSA-162582
Vesicle-mediated transport R-HSA-5653656
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Insulin processing R-HSA-264876
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by ALK in cancer R-HSA-9700206
Kinesins R-HSA-983189
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Hemostasis R-HSA-109582
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK fusions and activated point mutants R-HSA-9725370
RHO GTPases activate KTN1 R-HSA-5625970
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Insulin processing R-HSA-264876
Signal Transduction R-HSA-162582
Membrane Trafficking R-HSA-199991
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Adaptive Immune System R-HSA-1280218
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Kinesins R-HSA-983189
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signaling by ALK in cancer R-HSA-9700206
Golgi-to-ER retrograde transport R-HSA-8856688
MHC class II antigen presentation R-HSA-2132295
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Hemostasis R-HSA-109582
RHO GTPase Effectors R-HSA-195258
Immune System R-HSA-168256
Signaling by Rho GTPases R-HSA-194315
Vesicle-mediated transport R-HSA-5653656
RHO GTPases activate KTN1 R-HSA-5625970
Disease R-HSA-1643685
Hemostasis R-HSA-109582
Kinesins R-HSA-983189
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MHC class II antigen presentation R-HSA-2132295
Metabolism of proteins R-HSA-392499
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Signal Transduction R-HSA-162582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Insulin processing R-HSA-264876
Membrane Trafficking R-HSA-199991
RHO GTPase Effectors R-HSA-195258
Peptide hormone metabolism R-HSA-2980736
Signaling by Rho GTPases R-HSA-194315
RHO GTPases activate KTN1 R-HSA-5625970
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Golgi-to-ER retrograde transport R-HSA-8856688
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Immune System R-HSA-168256
Signaling by ALK in cancer R-HSA-9700206
Disease R-HSA-1643685
Vesicle-mediated transport R-HSA-5653656
Adaptive Immune System R-HSA-1280218
Golgi-to-ER retrograde transport R-HSA-8856688
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Peptide hormone metabolism R-HSA-2980736
Disease R-HSA-1643685
RHO GTPase Effectors R-HSA-195258
Adaptive Immune System R-HSA-1280218
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Kinesins R-HSA-983189
Membrane Trafficking R-HSA-199991
Immune System R-HSA-168256
Vesicle-mediated transport R-HSA-5653656
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Hemostasis R-HSA-109582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Signaling by ALK in cancer R-HSA-9700206
Insulin processing R-HSA-264876
Signal Transduction R-HSA-162582
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases R-HSA-194315
Metabolism of proteins R-HSA-392499
MHC class II antigen presentation R-HSA-2132295
RHO GTPases activate KTN1 R-HSA-5625970
Adaptive Immune System R-HSA-1280218
Peptide hormone metabolism R-HSA-2980736
Insulin processing R-HSA-264876
Signal Transduction R-HSA-162582
Kinesins R-HSA-983189
MHC class II antigen presentation R-HSA-2132295
RHO GTPase Effectors R-HSA-195258
Signaling by ALK in cancer R-HSA-9700206
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Disease R-HSA-1643685
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signaling by Rho GTPases R-HSA-194315
Immune System R-HSA-168256
RHO GTPases activate KTN1 R-HSA-5625970
Golgi-to-ER retrograde transport R-HSA-8856688
Vesicle-mediated transport R-HSA-5653656
Metabolism of proteins R-HSA-392499
Hemostasis R-HSA-109582
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Membrane Trafficking R-HSA-199991
Vesicle-mediated transport R-HSA-5653656
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Membrane Trafficking R-HSA-199991
Peptide hormone metabolism R-HSA-2980736
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Signaling by Rho GTPases R-HSA-194315
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Kinesins R-HSA-983189
RHO GTPase Effectors R-HSA-195258
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Disease R-HSA-1643685
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Insulin processing R-HSA-264876
RHO GTPases activate KTN1 R-HSA-5625970
Hemostasis R-HSA-109582
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
Golgi-to-ER retrograde transport R-HSA-8856688
MHC class II antigen presentation R-HSA-2132295
Signaling by ALK in cancer R-HSA-9700206

Expression Atlas ENSG00000170759
NCBI gene (formerly Entrezgene) 3799
GeneCards 6324
HGNC Symbol HGNC:6324
MIM gene 602809
UniProtKB Gene Name V9HW29
WikiGene 3799
Gene: RET
Ensembl ID : ENSG00000165731
Description: ret proto-oncogene
Gene Synonyms: CDHF12,CDHR16,HSCR1,MEN2A,MEN2B,MTC1,PTC,RET51
14 APIs:
205 Possible Orthologues:

Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
NPAS4 regulates expression of target genes R-HSA-9768919
Developmental Biology R-HSA-1266738
RET signaling R-HSA-8853659
Axon guidance R-HSA-422475
Transcriptional Regulation by NPAS4 R-HSA-9634815
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
NPAS4 regulates expression of target genes R-HSA-9768919
MAPK1/MAPK3 signaling R-HSA-5684996
RET signaling R-HSA-8853659
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by NPAS4 R-HSA-9634815
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
MAPK family signaling cascades R-HSA-5683057
Generic Transcription Pathway R-HSA-212436
RAF/MAP kinase cascade R-HSA-5673001
NPAS4 regulates expression of target genes R-HSA-9768919
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Nervous system development R-HSA-9675108
MAPK family signaling cascades R-HSA-5683057
RET signaling R-HSA-8853659
Axon guidance R-HSA-422475
Transcriptional Regulation by NPAS4 R-HSA-9634815
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
NPAS4 regulates expression of target genes R-HSA-9768919
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
Developmental Biology R-HSA-1266738
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Transcriptional Regulation by NPAS4 R-HSA-9634815
RNA Polymerase II Transcription R-HSA-73857
RET signaling R-HSA-8853659
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Transcriptional Regulation by NPAS4 R-HSA-9634815
NPAS4 regulates expression of target genes R-HSA-9768919
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
RET signaling R-HSA-8853659
Generic Transcription Pathway R-HSA-212436
Nervous system development R-HSA-9675108
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Nervous system development R-HSA-9675108
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
RET signaling R-HSA-8853659
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
NPAS4 regulates expression of target genes R-HSA-9768919
Transcriptional Regulation by NPAS4 R-HSA-9634815
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
RET signaling R-HSA-8853659
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
NPAS4 regulates expression of target genes R-HSA-9768919
RAF/MAP kinase cascade R-HSA-5673001
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Transcriptional Regulation by NPAS4 R-HSA-9634815
Axon guidance R-HSA-422475
NPAS4 regulates expression of target genes R-HSA-9768919
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
Transcriptional Regulation by NPAS4 R-HSA-9634815
RET signaling R-HSA-8853659
MAPK1/MAPK3 signaling R-HSA-5684996
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Axon guidance R-HSA-422475
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
NPAS4 regulates expression of target genes R-HSA-9768919
RET signaling R-HSA-8853659
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional Regulation by NPAS4 R-HSA-9634815
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
MAPK1/MAPK3 signaling R-HSA-5684996
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
NPAS4 regulates expression of target genes R-HSA-9768919
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
Developmental Biology R-HSA-1266738
RET signaling R-HSA-8853659
Transcriptional Regulation by NPAS4 R-HSA-9634815
Nervous system development R-HSA-9675108
RAF/MAP kinase cascade R-HSA-5673001
NPAS4 regulates expression of target genes R-HSA-9768919
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by NPAS4 R-HSA-9634815
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
RET signaling R-HSA-8853659

Expression Atlas ENSG00000165731
LRG display in Ensembl gene LRG_518
NCBI gene (formerly Entrezgene) 5979
GeneCards 9967
HGNC Symbol HGNC:9967
MIM gene 164761
MIM morbid 171400
UniProtKB Gene Name P07949
WikiGene 5979