Gene: CRHR1
Ensembl ID : ENSG00000120088
Description: corticotropin releasing hormone receptor 1
Gene Synonyms: CRF-R,CRF1,CRHR
5 APIs:
208 Possible Orthologues:

Class B/2 (Secretin family receptors) R-HSA-373080
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Class B/2 (Secretin family receptors) R-HSA-373080
Class B/2 (Secretin family receptors) R-HSA-373080
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Class B/2 (Secretin family receptors) R-HSA-373080
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Class B/2 (Secretin family receptors) R-HSA-373080
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Class B/2 (Secretin family receptors) R-HSA-373080
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Class B/2 (Secretin family receptors) R-HSA-373080
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
Class B/2 (Secretin family receptors) R-HSA-373080
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
Class B/2 (Secretin family receptors) R-HSA-373080
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Class B/2 (Secretin family receptors) R-HSA-373080
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
Class B/2 (Secretin family receptors) R-HSA-373080
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396

Expression Atlas ENSG00000120088
NCBI gene (formerly Entrezgene) 1394
GeneCards 2357
HGNC Symbol HGNC:2357
MIM gene 122561
UniProtKB Gene Name P34998
WikiGene 1394
Gene: CASP8
Ensembl ID : ENSG00000064012
Description: caspase 8
Gene Synonyms: CASP-8,FLICE,MACH,MCH5
1 APIs:
132 Possible Orthologues:

CLEC7A/inflammasome pathway R-HSA-5660668
Diseases of programmed cell death R-HSA-9645723
NOD1/2 Signaling Pathway R-HSA-168638
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulation of necroptotic cell death R-HSA-5675482
TRAIL signaling R-HSA-75158
Programmed Cell Death R-HSA-5357801
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Cytokine Signaling in Immune system R-HSA-1280215
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signal Transduction R-HSA-162582
MyD88 cascade initiated on plasma membrane R-HSA-975871
Death Receptor Signaling R-HSA-73887
TRIF-mediated programmed cell death R-HSA-2562578
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TNF signaling R-HSA-75893
FasL/ CD95L signaling R-HSA-75157
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Disease R-HSA-1643685
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Regulated Necrosis R-HSA-5218859
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Signaling by Interleukins R-HSA-449147
Toll-like Receptor Cascades R-HSA-168898
RIPK1-mediated regulated necrosis R-HSA-5213460
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of TNFR1 signaling R-HSA-5357905
CASP8 activity is inhibited R-HSA-5218900
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TNFR1-induced proapoptotic signaling R-HSA-5357786
Dimerization of procaspase-8 R-HSA-69416
Apoptotic execution phase R-HSA-75153
Regulation of NF-kappa B signaling R-HSA-9758274
MyD88 dependent cascade initiated on endosome R-HSA-975155
CLEC7A (Dectin-1) signaling R-HSA-5607764
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-1 family signaling R-HSA-446652
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Innate Immune System R-HSA-168249
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Apoptotic cleavage of cellular proteins R-HSA-111465
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Immune System R-HSA-168256
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Interleukin-1 signaling R-HSA-9020702
C-type lectin receptors (CLRs) R-HSA-5621481
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation by c-FLIP R-HSA-3371378
Apoptosis R-HSA-109581
TRIF-mediated programmed cell death R-HSA-2562578
Regulation by c-FLIP R-HSA-3371378
Toll-like Receptor Cascades R-HSA-168898
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Regulation of TNFR1 signaling R-HSA-5357905
Diseases of programmed cell death R-HSA-9645723
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
CASP8 activity is inhibited R-HSA-5218900
CLEC7A/inflammasome pathway R-HSA-5660668
Death Receptor Signaling R-HSA-73887
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Immune System R-HSA-168256
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Apoptotic execution phase R-HSA-75153
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Cytokine Signaling in Immune system R-HSA-1280215
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Regulation of NF-kappa B signaling R-HSA-9758274
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
CLEC7A (Dectin-1) signaling R-HSA-5607764
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Interleukin-1 family signaling R-HSA-446652
Apoptotic cleavage of cellular proteins R-HSA-111465
NOD1/2 Signaling Pathway R-HSA-168638
Signal Transduction R-HSA-162582
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Interleukin-1 signaling R-HSA-9020702
TNFR1-induced proapoptotic signaling R-HSA-5357786
FasL/ CD95L signaling R-HSA-75157
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulated Necrosis R-HSA-5218859
Apoptosis R-HSA-109581
Signaling by Interleukins R-HSA-449147
Regulation of necroptotic cell death R-HSA-5675482
C-type lectin receptors (CLRs) R-HSA-5621481
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
RIPK1-mediated regulated necrosis R-HSA-5213460
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TNF signaling R-HSA-75893
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TRAIL signaling R-HSA-75158
Intrinsic Pathway for Apoptosis R-HSA-109606
Programmed Cell Death R-HSA-5357801
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 dependent cascade initiated on endosome R-HSA-975155
Dimerization of procaspase-8 R-HSA-69416
Disease R-HSA-1643685
FasL/ CD95L signaling R-HSA-75157
TNFR1-induced proapoptotic signaling R-HSA-5357786
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of TNFR1 signaling R-HSA-5357905
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Innate Immune System R-HSA-168249
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RIPK1-mediated regulated necrosis R-HSA-5213460
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TNF signaling R-HSA-75893
CLEC7A (Dectin-1) signaling R-HSA-5607764
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Death Receptor Signaling R-HSA-73887
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Regulation by c-FLIP R-HSA-3371378
Immune System R-HSA-168256
Diseases of programmed cell death R-HSA-9645723
Apoptotic execution phase R-HSA-75153
Regulation of NF-kappa B signaling R-HSA-9758274
Programmed Cell Death R-HSA-5357801
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
CASP8 activity is inhibited R-HSA-5218900
Apoptosis R-HSA-109581
TRIF-mediated programmed cell death R-HSA-2562578
CLEC7A/inflammasome pathway R-HSA-5660668
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Disease R-HSA-1643685
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAIL signaling R-HSA-75158
Regulated Necrosis R-HSA-5218859
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Interleukin-1 signaling R-HSA-9020702
Intrinsic Pathway for Apoptosis R-HSA-109606
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Apoptotic cleavage of cellular proteins R-HSA-111465
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Regulation of necroptotic cell death R-HSA-5675482
NOD1/2 Signaling Pathway R-HSA-168638
Dimerization of procaspase-8 R-HSA-69416
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-1 family signaling R-HSA-446652
CASP8 activity is inhibited R-HSA-5218900
CLEC7A (Dectin-1) signaling R-HSA-5607764
TRIF-mediated programmed cell death R-HSA-2562578
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Apoptotic cleavage of cellular proteins R-HSA-111465
TNFR1-induced proapoptotic signaling R-HSA-5357786
Programmed Cell Death R-HSA-5357801
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Regulation by c-FLIP R-HSA-3371378
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
C-type lectin receptors (CLRs) R-HSA-5621481
TRAIL signaling R-HSA-75158
Innate Immune System R-HSA-168249
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Diseases of programmed cell death R-HSA-9645723
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TNF signaling R-HSA-75893
Interleukin-1 family signaling R-HSA-446652
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Disease R-HSA-1643685
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Death Receptor Signaling R-HSA-73887
RIPK1-mediated regulated necrosis R-HSA-5213460
Apoptotic execution phase R-HSA-75153
Regulation of TNFR1 signaling R-HSA-5357905
MyD88 cascade initiated on plasma membrane R-HSA-975871
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Toll-like Receptor Cascades R-HSA-168898
Dimerization of procaspase-8 R-HSA-69416
NOD1/2 Signaling Pathway R-HSA-168638
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Regulation of NF-kappa B signaling R-HSA-9758274
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulated Necrosis R-HSA-5218859
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Regulation of necroptotic cell death R-HSA-5675482
MyD88-independent TLR4 cascade R-HSA-166166
FasL/ CD95L signaling R-HSA-75157
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
CLEC7A/inflammasome pathway R-HSA-5660668
Apoptosis R-HSA-109581
C-type lectin receptors (CLRs) R-HSA-5621481
Death Receptor Signaling R-HSA-73887
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TNFR1-induced proapoptotic signaling R-HSA-5357786
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
CLEC7A (Dectin-1) signaling R-HSA-5607764
MyD88 dependent cascade initiated on endosome R-HSA-975155
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Apoptotic cleavage of cellular proteins R-HSA-111465
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
RIPK1-mediated regulated necrosis R-HSA-5213460
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Immune System R-HSA-168256
Programmed Cell Death R-HSA-5357801
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
NOD1/2 Signaling Pathway R-HSA-168638
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Interleukin-1 family signaling R-HSA-446652
TNF signaling R-HSA-75893
Regulation by c-FLIP R-HSA-3371378
CLEC7A/inflammasome pathway R-HSA-5660668
MyD88-independent TLR4 cascade R-HSA-166166
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
CASP8 activity is inhibited R-HSA-5218900
Apoptotic execution phase R-HSA-75153
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Innate Immune System R-HSA-168249
Regulation of necroptotic cell death R-HSA-5675482
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Dimerization of procaspase-8 R-HSA-69416
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulated Necrosis R-HSA-5218859
Intrinsic Pathway for Apoptosis R-HSA-109606
Apoptosis R-HSA-109581
FasL/ CD95L signaling R-HSA-75157
TRAIL signaling R-HSA-75158
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll-like Receptor Cascades R-HSA-168898
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRIF-mediated programmed cell death R-HSA-2562578
Signaling by Interleukins R-HSA-449147
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Interleukin-1 signaling R-HSA-9020702
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Diseases of programmed cell death R-HSA-9645723
Regulation of TNFR1 signaling R-HSA-5357905
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Interleukins R-HSA-449147
CLEC7A/inflammasome pathway R-HSA-5660668
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of NF-kappa B signaling R-HSA-9758274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
TRIF-mediated programmed cell death R-HSA-2562578
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88 cascade initiated on plasma membrane R-HSA-975871
MyD88-independent TLR4 cascade R-HSA-166166
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Regulation by c-FLIP R-HSA-3371378
Signal Transduction R-HSA-162582
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
NOD1/2 Signaling Pathway R-HSA-168638
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
RIPK1-mediated regulated necrosis R-HSA-5213460
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TNF signaling R-HSA-75893
TNFR1-induced proapoptotic signaling R-HSA-5357786
MyD88 dependent cascade initiated on endosome R-HSA-975155
Disease R-HSA-1643685
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Apoptosis R-HSA-109581
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Toll-like Receptor Cascades R-HSA-168898
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Regulation of necroptotic cell death R-HSA-5675482
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Apoptotic execution phase R-HSA-75153
Programmed Cell Death R-HSA-5357801
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAIL signaling R-HSA-75158
FasL/ CD95L signaling R-HSA-75157
CASP8 activity is inhibited R-HSA-5218900
Innate Immune System R-HSA-168249
Dimerization of procaspase-8 R-HSA-69416
Death Receptor Signaling R-HSA-73887
Interleukin-1 signaling R-HSA-9020702
Diseases of programmed cell death R-HSA-9645723
Immune System R-HSA-168256
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Cytokine Signaling in Immune system R-HSA-1280215
Apoptotic cleavage of cellular proteins R-HSA-111465
Regulated Necrosis R-HSA-5218859
Intrinsic Pathway for Apoptosis R-HSA-109606
Interleukin-1 family signaling R-HSA-446652
C-type lectin receptors (CLRs) R-HSA-5621481
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
TNFR1-induced proapoptotic signaling R-HSA-5357786
MyD88-independent TLR4 cascade R-HSA-166166
Regulation by c-FLIP R-HSA-3371378
Regulated Necrosis R-HSA-5218859
FasL/ CD95L signaling R-HSA-75157
Death Receptor Signaling R-HSA-73887
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of NF-kappa B signaling R-HSA-9758274
Diseases of programmed cell death R-HSA-9645723
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Immune System R-HSA-168256
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Interleukin-1 family signaling R-HSA-446652
CASP8 activity is inhibited R-HSA-5218900
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Apoptosis R-HSA-109581
Regulation of necroptotic cell death R-HSA-5675482
Programmed Cell Death R-HSA-5357801
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Innate Immune System R-HSA-168249
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Apoptotic execution phase R-HSA-75153
NOD1/2 Signaling Pathway R-HSA-168638
TNF signaling R-HSA-75893
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
CLEC7A/inflammasome pathway R-HSA-5660668
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
RIPK1-mediated regulated necrosis R-HSA-5213460
Apoptotic cleavage of cellular proteins R-HSA-111465
MyD88 cascade initiated on plasma membrane R-HSA-975871
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
TRAIL signaling R-HSA-75158
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88 dependent cascade initiated on endosome R-HSA-975155
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by Interleukins R-HSA-449147
Dimerization of procaspase-8 R-HSA-69416
TRIF-mediated programmed cell death R-HSA-2562578
C-type lectin receptors (CLRs) R-HSA-5621481
Toll-like Receptor Cascades R-HSA-168898
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 dependent cascade initiated on endosome R-HSA-975155
Immune System R-HSA-168256
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRAIL signaling R-HSA-75158
CLEC7A (Dectin-1) signaling R-HSA-5607764
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Signal Transduction R-HSA-162582
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Innate Immune System R-HSA-168249
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
RIPK1-mediated regulated necrosis R-HSA-5213460
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Disease R-HSA-1643685
Regulated Necrosis R-HSA-5218859
TNFR1-induced proapoptotic signaling R-HSA-5357786
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Regulation of NF-kappa B signaling R-HSA-9758274
Apoptotic execution phase R-HSA-75153
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Dimerization of procaspase-8 R-HSA-69416
Regulation of necroptotic cell death R-HSA-5675482
Regulation of TNFR1 signaling R-HSA-5357905
Interleukin-1 signaling R-HSA-9020702
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
C-type lectin receptors (CLRs) R-HSA-5621481
TNF signaling R-HSA-75893
Regulation by c-FLIP R-HSA-3371378
Toll-like Receptor Cascades R-HSA-168898
FasL/ CD95L signaling R-HSA-75157
NOD1/2 Signaling Pathway R-HSA-168638
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
CASP8 activity is inhibited R-HSA-5218900
Apoptosis R-HSA-109581
Intrinsic Pathway for Apoptosis R-HSA-109606
CLEC7A/inflammasome pathway R-HSA-5660668
Death Receptor Signaling R-HSA-73887
Apoptotic cleavage of cellular proteins R-HSA-111465
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Diseases of programmed cell death R-HSA-9645723
Interleukin-1 family signaling R-HSA-446652
TRIF-mediated programmed cell death R-HSA-2562578
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Programmed Cell Death R-HSA-5357801
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulated Necrosis R-HSA-5218859
Dimerization of procaspase-8 R-HSA-69416
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Toll-like Receptor Cascades R-HSA-168898
FasL/ CD95L signaling R-HSA-75157
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of TNFR1 signaling R-HSA-5357905
Disease R-HSA-1643685
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
TNF signaling R-HSA-75893
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signal Transduction R-HSA-162582
MyD88-independent TLR4 cascade R-HSA-166166
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRIF-mediated programmed cell death R-HSA-2562578
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Regulation of NF-kappa B signaling R-HSA-9758274
CASP8 activity is inhibited R-HSA-5218900
NOD1/2 Signaling Pathway R-HSA-168638
Death Receptor Signaling R-HSA-73887
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Regulation by c-FLIP R-HSA-3371378
TRAIL signaling R-HSA-75158
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 cascade initiated on plasma membrane R-HSA-975871
Apoptotic cleavage of cellular proteins R-HSA-111465
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by Interleukins R-HSA-449147
Intrinsic Pathway for Apoptosis R-HSA-109606
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Programmed Cell Death R-HSA-5357801
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Apoptotic execution phase R-HSA-75153
RIPK1-mediated regulated necrosis R-HSA-5213460
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Apoptosis R-HSA-109581
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Regulation of necroptotic cell death R-HSA-5675482
CLEC7A (Dectin-1) signaling R-HSA-5607764
Interleukin-1 signaling R-HSA-9020702
CLEC7A/inflammasome pathway R-HSA-5660668
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Diseases of programmed cell death R-HSA-9645723
TNFR1-induced proapoptotic signaling R-HSA-5357786
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation by c-FLIP R-HSA-3371378
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Dimerization of procaspase-8 R-HSA-69416
Diseases of programmed cell death R-HSA-9645723
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
C-type lectin receptors (CLRs) R-HSA-5621481
Regulated Necrosis R-HSA-5218859
Interleukin-1 family signaling R-HSA-446652
Programmed Cell Death R-HSA-5357801
Death Receptor Signaling R-HSA-73887
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
RIPK1-mediated regulated necrosis R-HSA-5213460
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Interleukins R-HSA-449147
Apoptotic execution phase R-HSA-75153
Cytokine Signaling in Immune system R-HSA-1280215
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
NOD1/2 Signaling Pathway R-HSA-168638
Apoptotic cleavage of cellular proteins R-HSA-111465
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRAIL signaling R-HSA-75158
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Interleukin-1 signaling R-HSA-9020702
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Immune System R-HSA-168256
CASP8 activity is inhibited R-HSA-5218900
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
FasL/ CD95L signaling R-HSA-75157
CLEC7A/inflammasome pathway R-HSA-5660668
TNFR1-induced proapoptotic signaling R-HSA-5357786
Disease R-HSA-1643685
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRIF-mediated programmed cell death R-HSA-2562578
TNF signaling R-HSA-75893
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
CLEC7A (Dectin-1) signaling R-HSA-5607764
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Regulation of NF-kappa B signaling R-HSA-9758274
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
MyD88-independent TLR4 cascade R-HSA-166166
Regulation of necroptotic cell death R-HSA-5675482
Apoptosis R-HSA-109581
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061

Expression Atlas ENSG00000064012
LRG display in Ensembl gene LRG_34
NCBI gene (formerly Entrezgene) 841
GeneCards 1509
HGNC Symbol HGNC:1509
MIM gene 601763
MIM morbid 607271
UniProtKB Gene Name Q14790
WikiGene 841
Gene: CASP1
Ensembl ID : ENSG00000137752
Description: caspase 1
Gene Synonyms: ICE,IL1BC
2 APIs:
427 Possible Orthologues:

RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
The AIM2 inflammasome R-HSA-844615
Purinergic signaling in leishmaniasis infection R-HSA-9660826
NOD1/2 Signaling Pathway R-HSA-168638
Cytokine Signaling in Immune system R-HSA-1280215
Gene expression (Transcription) R-HSA-74160
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
The IPAF inflammasome R-HSA-844623
Pyroptosis R-HSA-5620971
Infectious disease R-HSA-5663205
Interleukin-1 processing R-HSA-448706
Signaling by Interleukins R-HSA-449147
The NLRP3 inflammasome R-HSA-844456
Inflammasomes R-HSA-622312
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV Infections R-HSA-9679506
Leishmania infection R-HSA-9658195
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Regulated Necrosis R-HSA-5218859
Programmed Cell Death R-HSA-5357801
Interleukin-37 signaling R-HSA-9008059
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-1-host interactions R-HSA-9692914
Interleukin-1 family signaling R-HSA-446652
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
Infectious disease R-HSA-5663205
The AIM2 inflammasome R-HSA-844615
Regulated Necrosis R-HSA-5218859
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Cytokine Signaling in Immune system R-HSA-1280215
Leishmania infection R-HSA-9658195
Pyroptosis R-HSA-5620971
Programmed Cell Death R-HSA-5357801
Generic Transcription Pathway R-HSA-212436
Cell recruitment (pro-inflammatory response) R-HSA-9664424
The NLRP3 inflammasome R-HSA-844456
Gene expression (Transcription) R-HSA-74160
Inflammasomes R-HSA-622312
Innate Immune System R-HSA-168249
Interleukin-1 processing R-HSA-448706
SARS-CoV-1-host interactions R-HSA-9692914
Interleukin-37 signaling R-HSA-9008059
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
The IPAF inflammasome R-HSA-844623
Disease R-HSA-1643685
Signaling by Interleukins R-HSA-449147
Interleukin-1 family signaling R-HSA-446652
SARS-CoV-1 Infection R-HSA-9678108
NOD1/2 Signaling Pathway R-HSA-168638
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV Infections R-HSA-9679506
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Immune System R-HSA-168256
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Infectious disease R-HSA-5663205
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Generic Transcription Pathway R-HSA-212436
The NLRP3 inflammasome R-HSA-844456
Cytokine Signaling in Immune system R-HSA-1280215
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV Infections R-HSA-9679506
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Innate Immune System R-HSA-168249
The IPAF inflammasome R-HSA-844623
NOD1/2 Signaling Pathway R-HSA-168638
Interleukin-37 signaling R-HSA-9008059
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Regulated Necrosis R-HSA-5218859
SARS-CoV-1-host interactions R-HSA-9692914
Leishmania infection R-HSA-9658195
SARS-CoV-1 Infection R-HSA-9678108
Inflammasomes R-HSA-622312
Disease R-HSA-1643685
The AIM2 inflammasome R-HSA-844615
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Transcriptional Regulation by TP53 R-HSA-3700989
Pyroptosis R-HSA-5620971
Interleukin-1 processing R-HSA-448706
RNA Polymerase II Transcription R-HSA-73857
Cytokine Signaling in Immune system R-HSA-1280215
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
Signaling by Interleukins R-HSA-449147
Inflammasomes R-HSA-622312
Pyroptosis R-HSA-5620971
Disease R-HSA-1643685
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Gene expression (Transcription) R-HSA-74160
SARS-CoV Infections R-HSA-9679506
SARS-CoV-1-host interactions R-HSA-9692914
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Cell recruitment (pro-inflammatory response) R-HSA-9664424
The NLRP3 inflammasome R-HSA-844456
Regulated Necrosis R-HSA-5218859
Immune System R-HSA-168256
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Programmed Cell Death R-HSA-5357801
The IPAF inflammasome R-HSA-844623
Innate Immune System R-HSA-168249
Leishmania infection R-HSA-9658195
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 processing R-HSA-448706
The AIM2 inflammasome R-HSA-844615
NOD1/2 Signaling Pathway R-HSA-168638
Interleukin-37 signaling R-HSA-9008059
SARS-CoV-1 Infection R-HSA-9678108
Transcriptional Regulation by TP53 R-HSA-3700989
The NLRP3 inflammasome R-HSA-844456
The IPAF inflammasome R-HSA-844623
NOD1/2 Signaling Pathway R-HSA-168638
Interleukin-1 processing R-HSA-448706
RNA Polymerase II Transcription R-HSA-73857
Leishmania infection R-HSA-9658195
Regulated Necrosis R-HSA-5218859
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Immune System R-HSA-168256
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Cytokine Signaling in Immune system R-HSA-1280215
The AIM2 inflammasome R-HSA-844615
Inflammasomes R-HSA-622312
Generic Transcription Pathway R-HSA-212436
Signaling by Interleukins R-HSA-449147
Pyroptosis R-HSA-5620971
Innate Immune System R-HSA-168249
SARS-CoV-1 Infection R-HSA-9678108
Gene expression (Transcription) R-HSA-74160
SARS-CoV-1-host interactions R-HSA-9692914
Infectious disease R-HSA-5663205
Interleukin-37 signaling R-HSA-9008059
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Transcriptional Regulation by TP53 R-HSA-3700989
Interleukin-1 family signaling R-HSA-446652
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Programmed Cell Death R-HSA-5357801
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Leishmania infection R-HSA-9658195
Pyroptosis R-HSA-5620971
SARS-CoV-1 Infection R-HSA-9678108
Inflammasomes R-HSA-622312
Disease R-HSA-1643685
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV Infections R-HSA-9679506
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Cytokine Signaling in Immune system R-HSA-1280215
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Generic Transcription Pathway R-HSA-212436
Regulated Necrosis R-HSA-5218859
Innate Immune System R-HSA-168249
The NLRP3 inflammasome R-HSA-844456
SARS-CoV-1-host interactions R-HSA-9692914
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Interleukin-1 processing R-HSA-448706
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Interleukin-37 signaling R-HSA-9008059
The IPAF inflammasome R-HSA-844623
Transcriptional Regulation by TP53 R-HSA-3700989
Programmed Cell Death R-HSA-5357801
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
NOD1/2 Signaling Pathway R-HSA-168638
Infectious disease R-HSA-5663205
Interleukin-1 family signaling R-HSA-446652
The AIM2 inflammasome R-HSA-844615
Cell recruitment (pro-inflammatory response) R-HSA-9664424

Expression Atlas ENSG00000137752
NCBI gene (formerly Entrezgene) 834
GeneCards 1499
HGNC Symbol HGNC:1499
MIM gene 147678
UniProtKB Gene Name Q5FBZ0
WikiGene 834
Gene: CTSS
Ensembl ID : ENSG00000163131
Description: cathepsin S
Gene Synonyms:
1 APIs:
270 Possible Orthologues:

Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
Endosomal/Vacuolar pathway R-HSA-1236977
Neutrophil degranulation R-HSA-6798695
Degradation of the extracellular matrix R-HSA-1474228
Immune System R-HSA-168256
Collagen formation R-HSA-1474290
MHC class II antigen presentation R-HSA-2132295
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Trafficking and processing of endosomal TLR R-HSA-1679131
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Trafficking and processing of endosomal TLR R-HSA-1679131
Toll-like Receptor Cascades R-HSA-168898
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
Extracellular matrix organization R-HSA-1474244
Adaptive Immune System R-HSA-1280218
Endosomal/Vacuolar pathway R-HSA-1236977
Immune System R-HSA-168256
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Collagen formation R-HSA-1474290
MHC class II antigen presentation R-HSA-2132295
Degradation of the extracellular matrix R-HSA-1474228
MHC class II antigen presentation R-HSA-2132295
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Degradation of the extracellular matrix R-HSA-1474228
Toll-like Receptor Cascades R-HSA-168898
Class I MHC mediated antigen processing & presentation R-HSA-983169
Collagen formation R-HSA-1474290
Endosomal/Vacuolar pathway R-HSA-1236977
Adaptive Immune System R-HSA-1280218
Trafficking and processing of endosomal TLR R-HSA-1679131
Immune System R-HSA-168256
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Antigen processing-Cross presentation R-HSA-1236975
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Collagen formation R-HSA-1474290
Extracellular matrix organization R-HSA-1474244
Trafficking and processing of endosomal TLR R-HSA-1679131
Endosomal/Vacuolar pathway R-HSA-1236977
MHC class II antigen presentation R-HSA-2132295
Antigen processing-Cross presentation R-HSA-1236975
Class I MHC mediated antigen processing & presentation R-HSA-983169
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Toll-like Receptor Cascades R-HSA-168898
Adaptive Immune System R-HSA-1280218
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Toll-like Receptor Cascades R-HSA-168898
Extracellular matrix organization R-HSA-1474244
Collagen formation R-HSA-1474290
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Trafficking and processing of endosomal TLR R-HSA-1679131
MHC class II antigen presentation R-HSA-2132295
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Class I MHC mediated antigen processing & presentation R-HSA-983169
Endosomal/Vacuolar pathway R-HSA-1236977
Antigen processing-Cross presentation R-HSA-1236975
Endosomal/Vacuolar pathway R-HSA-1236977
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neutrophil degranulation R-HSA-6798695
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Innate Immune System R-HSA-168249
Collagen formation R-HSA-1474290
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Adaptive Immune System R-HSA-1280218
Trafficking and processing of endosomal TLR R-HSA-1679131
MHC class II antigen presentation R-HSA-2132295
Degradation of the extracellular matrix R-HSA-1474228
Toll-like Receptor Cascades R-HSA-168898
MHC class II antigen presentation R-HSA-2132295
Class I MHC mediated antigen processing & presentation R-HSA-983169
Endosomal/Vacuolar pathway R-HSA-1236977
Adaptive Immune System R-HSA-1280218
Collagen formation R-HSA-1474290
Toll-like Receptor Cascades R-HSA-168898
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Extracellular matrix organization R-HSA-1474244
Neutrophil degranulation R-HSA-6798695
Trafficking and processing of endosomal TLR R-HSA-1679131
Degradation of the extracellular matrix R-HSA-1474228
Collagen formation R-HSA-1474290
Trafficking and processing of endosomal TLR R-HSA-1679131
Class I MHC mediated antigen processing & presentation R-HSA-983169
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Endosomal/Vacuolar pathway R-HSA-1236977
Innate Immune System R-HSA-168249
MHC class II antigen presentation R-HSA-2132295
Antigen processing-Cross presentation R-HSA-1236975
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Degradation of the extracellular matrix R-HSA-1474228
Adaptive Immune System R-HSA-1280218
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Degradation of the extracellular matrix R-HSA-1474228
Adaptive Immune System R-HSA-1280218
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Collagen formation R-HSA-1474290
MHC class II antigen presentation R-HSA-2132295
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Endosomal/Vacuolar pathway R-HSA-1236977
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Trafficking and processing of endosomal TLR R-HSA-1679131
Class I MHC mediated antigen processing & presentation R-HSA-983169
Trafficking and processing of endosomal TLR R-HSA-1679131
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
Innate Immune System R-HSA-168249
MHC class II antigen presentation R-HSA-2132295
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Degradation of the extracellular matrix R-HSA-1474228
Endosomal/Vacuolar pathway R-HSA-1236977
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Adaptive Immune System R-HSA-1280218
Collagen formation R-HSA-1474290

Expression Atlas ENSG00000163131
NCBI gene (formerly Entrezgene) 1520
GeneCards 2545
HGNC Symbol HGNC:2545
MIM gene 116845
UniProtKB Gene Name U3KQE7
WikiGene 1520
Gene: CTSK
Ensembl ID : ENSG00000143387
Description: cathepsin K
Gene Synonyms: CTSO,CTSO2,PKND,PYCD
2 APIs:
246 Possible Orthologues:

Innate Immune System R-HSA-168249
Collagen degradation R-HSA-1442490
RNA Polymerase II Transcription R-HSA-73857
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
MHC class II antigen presentation R-HSA-2132295
Trafficking and processing of endosomal TLR R-HSA-1679131
Generic Transcription Pathway R-HSA-212436
Toll-like Receptor Cascades R-HSA-168898
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of the extracellular matrix R-HSA-1474228
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Collagen degradation R-HSA-1442490
Gene expression (Transcription) R-HSA-74160
Degradation of the extracellular matrix R-HSA-1474228
Toll-like Receptor Cascades R-HSA-168898
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Trafficking and processing of endosomal TLR R-HSA-1679131
Activation of Matrix Metalloproteinases R-HSA-1592389
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
Extracellular matrix organization R-HSA-1474244
MHC class II antigen presentation R-HSA-2132295
Transcriptional regulation by RUNX1 R-HSA-8878171
RNA Polymerase II Transcription R-HSA-73857
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Gene expression (Transcription) R-HSA-74160
Collagen degradation R-HSA-1442490
Activation of Matrix Metalloproteinases R-HSA-1592389
Immune System R-HSA-168256
Trafficking and processing of endosomal TLR R-HSA-1679131
Degradation of the extracellular matrix R-HSA-1474228
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Adaptive Immune System R-HSA-1280218
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX1 R-HSA-8878171
MHC class II antigen presentation R-HSA-2132295
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Immune System R-HSA-168256
Degradation of the extracellular matrix R-HSA-1474228
Trafficking and processing of endosomal TLR R-HSA-1679131
Innate Immune System R-HSA-168249
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
Collagen degradation R-HSA-1442490
Extracellular matrix organization R-HSA-1474244
Adaptive Immune System R-HSA-1280218
Generic Transcription Pathway R-HSA-212436
Toll-like Receptor Cascades R-HSA-168898
MHC class II antigen presentation R-HSA-2132295
Activation of Matrix Metalloproteinases R-HSA-1592389
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Collagen degradation R-HSA-1442490
Adaptive Immune System R-HSA-1280218
Toll-like Receptor Cascades R-HSA-168898
Gene expression (Transcription) R-HSA-74160
Activation of Matrix Metalloproteinases R-HSA-1592389
Immune System R-HSA-168256
Degradation of the extracellular matrix R-HSA-1474228
MHC class II antigen presentation R-HSA-2132295
Trafficking and processing of endosomal TLR R-HSA-1679131
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX1 R-HSA-8878171
Extracellular matrix organization R-HSA-1474244
Generic Transcription Pathway R-HSA-212436
Innate Immune System R-HSA-168249
Collagen degradation R-HSA-1442490
Degradation of the extracellular matrix R-HSA-1474228
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
MHC class II antigen presentation R-HSA-2132295
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Activation of Matrix Metalloproteinases R-HSA-1592389
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
Trafficking and processing of endosomal TLR R-HSA-1679131
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Collagen degradation R-HSA-1442490
Trafficking and processing of endosomal TLR R-HSA-1679131
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Generic Transcription Pathway R-HSA-212436
Activation of Matrix Metalloproteinases R-HSA-1592389
Toll-like Receptor Cascades R-HSA-168898
MHC class II antigen presentation R-HSA-2132295
Transcriptional regulation by RUNX1 R-HSA-8878171
Adaptive Immune System R-HSA-1280218
Extracellular matrix organization R-HSA-1474244
RNA Polymerase II Transcription R-HSA-73857
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Trafficking and processing of endosomal TLR R-HSA-1679131
Degradation of the extracellular matrix R-HSA-1474228
RNA Polymerase II Transcription R-HSA-73857
MHC class II antigen presentation R-HSA-2132295
Adaptive Immune System R-HSA-1280218
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of Matrix Metalloproteinases R-HSA-1592389
Collagen degradation R-HSA-1442490
MHC class II antigen presentation R-HSA-2132295
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
Generic Transcription Pathway R-HSA-212436
Degradation of the extracellular matrix R-HSA-1474228
Activation of Matrix Metalloproteinases R-HSA-1592389
RNA Polymerase II Transcription R-HSA-73857
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Trafficking and processing of endosomal TLR R-HSA-1679131
Collagen degradation R-HSA-1442490
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Innate Immune System R-HSA-168249
Degradation of the extracellular matrix R-HSA-1474228
RNA Polymerase II Transcription R-HSA-73857
Toll-like Receptor Cascades R-HSA-168898
MHC class II antigen presentation R-HSA-2132295
Collagen degradation R-HSA-1442490
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of Matrix Metalloproteinases R-HSA-1592389
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Immune System R-HSA-168256
Extracellular matrix organization R-HSA-1474244
Trafficking and processing of endosomal TLR R-HSA-1679131
Adaptive Immune System R-HSA-1280218

Expression Atlas ENSG00000143387
NCBI gene (formerly Entrezgene) 1513
GeneCards 2536
HGNC Symbol HGNC:2536
MIM gene 601105
MIM morbid 265800
UniProtKB Gene Name Q5QP40
WikiGene 1513
Gene: CYP11B1
Ensembl ID : ENSG00000160882
Description: cytochrome P450 family 11 subfamily B member 1
Gene Synonyms: CPN1,CYP11B,FHI,P450C11
2 APIs:
40 Possible Orthologues:

Glucocorticoid biosynthesis R-HSA-194002
Defective CYP11B1 causes AH4 R-HSA-5579017
Cytochrome P450 - arranged by substrate type R-HSA-211897
Phase I - Functionalization of compounds R-HSA-211945
Disease R-HSA-1643685
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Diseases of metabolism R-HSA-5668914
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of steroids R-HSA-8957322
Metabolism of steroid hormones R-HSA-196071
Metabolism R-HSA-1430728
Diseases of metabolism R-HSA-5668914
Glucocorticoid biosynthesis R-HSA-194002
Biological oxidations R-HSA-211859
Endogenous sterols R-HSA-211976
Disease R-HSA-1643685
Metabolism of lipids R-HSA-556833
Cytochrome P450 - arranged by substrate type R-HSA-211897
Defective CYP11B1 causes AH4 R-HSA-5579017
Defective CYP11B1 causes AH4 R-HSA-5579017
Cytochrome P450 - arranged by substrate type R-HSA-211897
Phase I - Functionalization of compounds R-HSA-211945
Diseases of metabolism R-HSA-5668914
Glucocorticoid biosynthesis R-HSA-194002
Endogenous sterols R-HSA-211976
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Biological oxidations R-HSA-211859
Disease R-HSA-1643685
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833

Expression Atlas ENSG00000160882
NCBI gene (formerly Entrezgene) 1584
GeneCards 2591
HGNC Symbol HGNC:2591
MIM gene 610613
MIM morbid 202010
UniProtKB Gene Name Q4VAR0
WikiGene 1584
Gene: CYP17A1
Ensembl ID : ENSG00000148795
Description: cytochrome P450 family 17 subfamily A member 1
Gene Synonyms: CPT7,CYP17,P450C17,S17AH
4 APIs:
211 Possible Orthologues:

Metabolism R-HSA-1430728
Metabolism of steroid hormones R-HSA-196071
Diseases of metabolism R-HSA-5668914
Disease R-HSA-1643685
Androgen biosynthesis R-HSA-193048
Defective CYP17A1 causes AH5 R-HSA-5579028
Metabolism of lipids R-HSA-556833
Glucocorticoid biosynthesis R-HSA-194002
Metabolism of steroids R-HSA-8957322
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism R-HSA-1430728
Glucocorticoid biosynthesis R-HSA-194002
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Androgen biosynthesis R-HSA-193048
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Metabolism of steroid hormones R-HSA-196071
Disease R-HSA-1643685
Diseases of metabolism R-HSA-5668914
Defective CYP17A1 causes AH5 R-HSA-5579028
Defective CYP17A1 causes AH5 R-HSA-5579028
Glucocorticoid biosynthesis R-HSA-194002
Metabolism of steroids R-HSA-8957322
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Disease R-HSA-1643685
Metabolism of steroid hormones R-HSA-196071
Androgen biosynthesis R-HSA-193048
Diseases of metabolism R-HSA-5668914
Defective CYP17A1 causes AH5 R-HSA-5579028
Diseases of metabolism R-HSA-5668914
Androgen biosynthesis R-HSA-193048
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
Glucocorticoid biosynthesis R-HSA-194002
Disease R-HSA-1643685
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism R-HSA-1430728
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism of steroids R-HSA-8957322
Glucocorticoid biosynthesis R-HSA-194002
Disease R-HSA-1643685
Defective CYP17A1 causes AH5 R-HSA-5579028
Diseases of metabolism R-HSA-5668914
Metabolism of lipids R-HSA-556833
Androgen biosynthesis R-HSA-193048
Metabolism of steroid hormones R-HSA-196071
Diseases of metabolism R-HSA-5668914
Metabolism of steroid hormones R-HSA-196071
Androgen biosynthesis R-HSA-193048
Metabolism R-HSA-1430728
Defective CYP17A1 causes AH5 R-HSA-5579028
Disease R-HSA-1643685
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Glucocorticoid biosynthesis R-HSA-194002
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Glucocorticoid biosynthesis R-HSA-194002
Metabolism of steroid hormones R-HSA-196071
Defective CYP17A1 causes AH5 R-HSA-5579028
Metabolism R-HSA-1430728
Androgen biosynthesis R-HSA-193048
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Disease R-HSA-1643685
Diseases of metabolism R-HSA-5668914
Defective CYP17A1 causes AH5 R-HSA-5579028
Androgen biosynthesis R-HSA-193048
Metabolism R-HSA-1430728
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism of steroids R-HSA-8957322
Disease R-HSA-1643685
Glucocorticoid biosynthesis R-HSA-194002
Metabolism of lipids R-HSA-556833
Diseases of metabolism R-HSA-5668914
Metabolism of steroid hormones R-HSA-196071
Diseases of metabolism R-HSA-5668914
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism of steroid hormones R-HSA-196071
Glucocorticoid biosynthesis R-HSA-194002
Disease R-HSA-1643685
Androgen biosynthesis R-HSA-193048
Defective CYP17A1 causes AH5 R-HSA-5579028
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Diseases of metabolism R-HSA-5668914
Metabolism of steroids R-HSA-8957322
Glucocorticoid biosynthesis R-HSA-194002
Disease R-HSA-1643685
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism R-HSA-1430728
Defective CYP17A1 causes AH5 R-HSA-5579028
Androgen biosynthesis R-HSA-193048

Expression Atlas ENSG00000148795
NCBI gene (formerly Entrezgene) 1586
GeneCards 2593
HGNC Symbol HGNC:2593
MIM gene 609300
MIM morbid 202110
UniProtKB Gene Name Q1HB44
WikiGene 1586
Gene: CYP19A1
Ensembl ID : ENSG00000137869
Description: cytochrome P450 family 19 subfamily A member 1
Gene Synonyms: ARO,ARO1,AROMATASE,CPV1,CYAR,CYP19,P-450AROM
5 APIs:
319 Possible Orthologues:

Defective CYP19A1 causes AEXS R-HSA-5579030
Endogenous sterols R-HSA-211976
Metabolism of steroid hormones R-HSA-196071
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Estrogen biosynthesis R-HSA-193144
Diseases of metabolism R-HSA-5668914
Biological oxidations R-HSA-211859
Metabolism of steroids R-HSA-8957322
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of steroid hormones R-HSA-196071
Defective CYP19A1 causes AEXS R-HSA-5579030
Endogenous sterols R-HSA-211976
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Phase I - Functionalization of compounds R-HSA-211945
Disease R-HSA-1643685
Estrogen biosynthesis R-HSA-193144
Diseases of metabolism R-HSA-5668914
Metabolism of steroids R-HSA-8957322
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Cytochrome P450 - arranged by substrate type R-HSA-211897
Biological oxidations R-HSA-211859
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Diseases of metabolism R-HSA-5668914
Disease R-HSA-1643685
Estrogen biosynthesis R-HSA-193144
Phase I - Functionalization of compounds R-HSA-211945
Defective CYP19A1 causes AEXS R-HSA-5579030
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of steroid hormones R-HSA-196071
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Biological oxidations R-HSA-211859
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Defective CYP19A1 causes AEXS R-HSA-5579030
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Diseases of metabolism R-HSA-5668914
Endogenous sterols R-HSA-211976
Metabolism R-HSA-1430728
Estrogen biosynthesis R-HSA-193144
Disease R-HSA-1643685
Metabolism of steroids R-HSA-8957322
Defective CYP19A1 causes AEXS R-HSA-5579030
Estrogen biosynthesis R-HSA-193144
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Diseases of metabolism R-HSA-5668914
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism R-HSA-1430728
Metabolism of steroid hormones R-HSA-196071
Disease R-HSA-1643685
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Defective CYP19A1 causes AEXS R-HSA-5579030
Endogenous sterols R-HSA-211976
Metabolism of steroids R-HSA-8957322
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism R-HSA-1430728
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism of lipids R-HSA-556833
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Disease R-HSA-1643685
Metabolism of steroid hormones R-HSA-196071
Diseases of metabolism R-HSA-5668914
Estrogen biosynthesis R-HSA-193144
Diseases of metabolism R-HSA-5668914
Estrogen biosynthesis R-HSA-193144
Metabolism of steroid hormones R-HSA-196071
Defective CYP19A1 causes AEXS R-HSA-5579030
Biological oxidations R-HSA-211859
Disease R-HSA-1643685
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Cytochrome P450 - arranged by substrate type R-HSA-211897
Endogenous sterols R-HSA-211976
Metabolism of steroids R-HSA-8957322
Disease R-HSA-1643685
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism R-HSA-1430728
Cytochrome P450 - arranged by substrate type R-HSA-211897
Phase I - Functionalization of compounds R-HSA-211945
Endogenous sterols R-HSA-211976
Estrogen biosynthesis R-HSA-193144
Diseases of metabolism R-HSA-5668914
Defective CYP19A1 causes AEXS R-HSA-5579030
Biological oxidations R-HSA-211859
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Endogenous sterols R-HSA-211976
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism of steroids R-HSA-8957322
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Metabolism of steroid hormones R-HSA-196071
Biological oxidations R-HSA-211859
Diseases of metabolism R-HSA-5668914
Estrogen biosynthesis R-HSA-193144
Metabolism R-HSA-1430728
Defective CYP19A1 causes AEXS R-HSA-5579030
Disease R-HSA-1643685
Cytochrome P450 - arranged by substrate type R-HSA-211897
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of lipids R-HSA-556833
Phase I - Functionalization of compounds R-HSA-211945
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Diseases of metabolism R-HSA-5668914
Defective CYP19A1 causes AEXS R-HSA-5579030
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Estrogen biosynthesis R-HSA-193144
Metabolism of steroid hormones R-HSA-196071
Disease R-HSA-1643685
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728

Expression Atlas ENSG00000137869
NCBI gene (formerly Entrezgene) 1588
GeneCards 2594
HGNC Symbol HGNC:2594
MIM gene 107910
MIM morbid 613546
UniProtKB Gene Name P11511
WikiGene 1588