Gene: ITGB3
Ensembl ID : ENSG00000259207
Description: integrin subunit beta 3
Gene Synonyms: CD61,GP3A,GPIIIA
9 APIs:
268 Possible Orthologues:

Axon guidance R-HSA-422475
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
p130Cas linkage to MAPK signaling for integrins R-HSA-372708
Integrin cell surface interactions R-HSA-216083
Platelet degranulation R-HSA-114608
Developmental Biology R-HSA-1266738
Platelet Aggregation (Plug Formation) R-HSA-76009
Signaling downstream of RAS mutants R-HSA-9649948
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Molecules associated with elastic fibres R-HSA-2129379
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Integrin signaling R-HSA-354192
ECM proteoglycans R-HSA-3000178
Hemostasis R-HSA-109582
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signaling by RAF1 mutants R-HSA-9656223
Disease R-HSA-1643685
Signaling by TGFB family members R-HSA-9006936
VEGFA-VEGFR2 Pathway R-HSA-4420097
Non-integrin membrane-ECM interactions R-HSA-3000171
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Oncogenic MAPK signaling R-HSA-6802957
MAPK1/MAPK3 signaling R-HSA-5684996
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by VEGF R-HSA-194138
Elastic fibre formation R-HSA-1566948
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194
MAPK family signaling cascades R-HSA-5683057
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signal transduction by L1 R-HSA-445144
Signaling by RAS mutants R-HSA-6802949
Nervous system development R-HSA-9675108
Signaling by TGF-beta Receptor Complex R-HSA-170834
Syndecan interactions R-HSA-3000170
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Extracellular matrix organization R-HSA-1474244
MAP2K and MAPK activation R-HSA-5674135
L1CAM interactions R-HSA-373760
PECAM1 interactions R-HSA-210990
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Cell surface interactions at the vascular wall R-HSA-202733
Elastic fibre formation R-HSA-1566948
Signal Transduction R-HSA-162582
Oncogenic MAPK signaling R-HSA-6802957
Disease R-HSA-1643685
p130Cas linkage to MAPK signaling for integrins R-HSA-372708
Axon guidance R-HSA-422475
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
PECAM1 interactions R-HSA-210990
Platelet degranulation R-HSA-114608
Signaling by RAF1 mutants R-HSA-9656223
Platelet activation, signaling and aggregation R-HSA-76002
Platelet Aggregation (Plug Formation) R-HSA-76009
Syndecan interactions R-HSA-3000170
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by TGFB family members R-HSA-9006936
Integrin cell surface interactions R-HSA-216083
Signaling by BRAF and RAF1 fusions R-HSA-6802952
VEGFA-VEGFR2 Pathway R-HSA-4420097
MAPK family signaling cascades R-HSA-5683057
Extracellular matrix organization R-HSA-1474244
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by TGF-beta Receptor Complex R-HSA-170834
ECM proteoglycans R-HSA-3000178
Integrin signaling R-HSA-354192
MAP2K and MAPK activation R-HSA-5674135
Signaling downstream of RAS mutants R-HSA-9649948
Hemostasis R-HSA-109582
Signaling by RAS mutants R-HSA-6802949
Molecules associated with elastic fibres R-HSA-2129379
Non-integrin membrane-ECM interactions R-HSA-3000171
Developmental Biology R-HSA-1266738
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by VEGF R-HSA-194138
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signal transduction by L1 R-HSA-445144
Nervous system development R-HSA-9675108
L1CAM interactions R-HSA-373760
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Extracellular matrix organization R-HSA-1474244
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by TGF-beta Receptor Complex R-HSA-170834
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
p130Cas linkage to MAPK signaling for integrins R-HSA-372708
Elastic fibre formation R-HSA-1566948
Signal transduction by L1 R-HSA-445144
ECM proteoglycans R-HSA-3000178
Nervous system development R-HSA-9675108
Integrin signaling R-HSA-354192
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Platelet degranulation R-HSA-114608
Non-integrin membrane-ECM interactions R-HSA-3000171
Hemostasis R-HSA-109582
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by VEGF R-HSA-194138
RAF/MAP kinase cascade R-HSA-5673001
Disease R-HSA-1643685
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by TGFB family members R-HSA-9006936
MAPK1/MAPK3 signaling R-HSA-5684996
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194
L1CAM interactions R-HSA-373760
Signaling by RAF1 mutants R-HSA-9656223
Molecules associated with elastic fibres R-HSA-2129379
Developmental Biology R-HSA-1266738
Signaling by RAS mutants R-HSA-6802949
Oncogenic MAPK signaling R-HSA-6802957
MAP2K and MAPK activation R-HSA-5674135
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
PECAM1 interactions R-HSA-210990
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signaling downstream of RAS mutants R-HSA-9649948
Axon guidance R-HSA-422475
Platelet Aggregation (Plug Formation) R-HSA-76009
Integrin cell surface interactions R-HSA-216083
Syndecan interactions R-HSA-3000170
MAPK family signaling cascades R-HSA-5683057
Extracellular matrix organization R-HSA-1474244
Signaling by VEGF R-HSA-194138
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Disease R-HSA-1643685
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Hemostasis R-HSA-109582
Signaling by TGF-beta Receptor Complex R-HSA-170834
Developmental Biology R-HSA-1266738
PECAM1 interactions R-HSA-210990
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Integrin signaling R-HSA-354192
MAP2K and MAPK activation R-HSA-5674135
p130Cas linkage to MAPK signaling for integrins R-HSA-372708
Cell surface interactions at the vascular wall R-HSA-202733
Platelet degranulation R-HSA-114608
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signal transduction by L1 R-HSA-445144
Oncogenic MAPK signaling R-HSA-6802957
Signaling downstream of RAS mutants R-HSA-9649948
Molecules associated with elastic fibres R-HSA-2129379
L1CAM interactions R-HSA-373760
Platelet Aggregation (Plug Formation) R-HSA-76009
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194
Syndecan interactions R-HSA-3000170
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Axon guidance R-HSA-422475
Platelet activation, signaling and aggregation R-HSA-76002
Nervous system development R-HSA-9675108
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Integrin cell surface interactions R-HSA-216083
ECM proteoglycans R-HSA-3000178
Non-integrin membrane-ECM interactions R-HSA-3000171
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Elastic fibre formation R-HSA-1566948
Signaling by RAS mutants R-HSA-6802949
Signal Transduction R-HSA-162582
Signaling by RAF1 mutants R-HSA-9656223
Signaling by TGFB family members R-HSA-9006936
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF/MAP kinase cascade R-HSA-5673001
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
L1CAM interactions R-HSA-373760
Elastic fibre formation R-HSA-1566948
p130Cas linkage to MAPK signaling for integrins R-HSA-372708
Integrin signaling R-HSA-354192
Disease R-HSA-1643685
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signaling by TGFB family members R-HSA-9006936
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
MAPK family signaling cascades R-HSA-5683057
Nervous system development R-HSA-9675108
MAP2K and MAPK activation R-HSA-5674135
Extracellular matrix organization R-HSA-1474244
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by RAS mutants R-HSA-6802949
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Platelet degranulation R-HSA-114608
Signaling by VEGF R-HSA-194138
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194
PECAM1 interactions R-HSA-210990
Signaling by TGF-beta Receptor Complex R-HSA-170834
VEGFA-VEGFR2 Pathway R-HSA-4420097
ECM proteoglycans R-HSA-3000178
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Syndecan interactions R-HSA-3000170
Platelet Aggregation (Plug Formation) R-HSA-76009
Non-integrin membrane-ECM interactions R-HSA-3000171
Developmental Biology R-HSA-1266738
Integrin cell surface interactions R-HSA-216083
Signaling downstream of RAS mutants R-HSA-9649948
Molecules associated with elastic fibres R-HSA-2129379
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Oncogenic MAPK signaling R-HSA-6802957
Signal transduction by L1 R-HSA-445144
Signaling by RAF1 mutants R-HSA-9656223
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Oncogenic MAPK signaling R-HSA-6802957
MAPK family signaling cascades R-HSA-5683057
TGF-beta receptor signaling activates SMADs R-HSA-2173789
RAF/MAP kinase cascade R-HSA-5673001
L1CAM interactions R-HSA-373760
Signal Transduction R-HSA-162582
Signaling downstream of RAS mutants R-HSA-9649948
Cell surface interactions at the vascular wall R-HSA-202733
Platelet Aggregation (Plug Formation) R-HSA-76009
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194
Hemostasis R-HSA-109582
Signaling by RAS mutants R-HSA-6802949
Integrin signaling R-HSA-354192
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by VEGF R-HSA-194138
Developmental Biology R-HSA-1266738
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Syndecan interactions R-HSA-3000170
MAP2K and MAPK activation R-HSA-5674135
Integrin cell surface interactions R-HSA-216083
Molecules associated with elastic fibres R-HSA-2129379
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Platelet activation, signaling and aggregation R-HSA-76002
VEGFA-VEGFR2 Pathway R-HSA-4420097
Axon guidance R-HSA-422475
p130Cas linkage to MAPK signaling for integrins R-HSA-372708
Extracellular matrix organization R-HSA-1474244
Signaling by TGFB family members R-HSA-9006936
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by RAF1 mutants R-HSA-9656223
Elastic fibre formation R-HSA-1566948
Nervous system development R-HSA-9675108
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
PECAM1 interactions R-HSA-210990
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
ECM proteoglycans R-HSA-3000178
Signaling by TGF-beta Receptor Complex R-HSA-170834
Non-integrin membrane-ECM interactions R-HSA-3000171
Signal transduction by L1 R-HSA-445144
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Platelet degranulation R-HSA-114608
Platelet degranulation R-HSA-114608
MAP2K and MAPK activation R-HSA-5674135
ECM proteoglycans R-HSA-3000178
Signaling by RAF1 mutants R-HSA-9656223
Signaling downstream of RAS mutants R-HSA-9649948
Elastic fibre formation R-HSA-1566948
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Cell surface interactions at the vascular wall R-HSA-202733
Disease R-HSA-1643685
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194
Signal transduction by L1 R-HSA-445144
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by RAS mutants R-HSA-6802949
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
Integrin signaling R-HSA-354192
Integrin cell surface interactions R-HSA-216083
L1CAM interactions R-HSA-373760
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Hemostasis R-HSA-109582
Molecules associated with elastic fibres R-HSA-2129379
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Nervous system development R-HSA-9675108
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Syndecan interactions R-HSA-3000170
PECAM1 interactions R-HSA-210990
MAPK1/MAPK3 signaling R-HSA-5684996
Non-integrin membrane-ECM interactions R-HSA-3000171
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by TGFB family members R-HSA-9006936
Signaling by VEGF R-HSA-194138
Platelet Aggregation (Plug Formation) R-HSA-76009
MAPK family signaling cascades R-HSA-5683057
p130Cas linkage to MAPK signaling for integrins R-HSA-372708
RAF/MAP kinase cascade R-HSA-5673001
Oncogenic MAPK signaling R-HSA-6802957
Extracellular matrix organization R-HSA-1474244
Developmental Biology R-HSA-1266738
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Disease R-HSA-1643685
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Elastic fibre formation R-HSA-1566948
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194
Nervous system development R-HSA-9675108
Platelet Aggregation (Plug Formation) R-HSA-76009
Platelet activation, signaling and aggregation R-HSA-76002
p130Cas linkage to MAPK signaling for integrins R-HSA-372708
Platelet degranulation R-HSA-114608
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Integrin cell surface interactions R-HSA-216083
Molecules associated with elastic fibres R-HSA-2129379
Extracellular matrix organization R-HSA-1474244
Signal Transduction R-HSA-162582
Signaling by RAF1 mutants R-HSA-9656223
PECAM1 interactions R-HSA-210990
Oncogenic MAPK signaling R-HSA-6802957
Signal transduction by L1 R-HSA-445144
Syndecan interactions R-HSA-3000170
Signaling by BRAF and RAF1 fusions R-HSA-6802952
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by RAS mutants R-HSA-6802949
MAPK family signaling cascades R-HSA-5683057
Developmental Biology R-HSA-1266738
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by VEGF R-HSA-194138
RAF/MAP kinase cascade R-HSA-5673001
Cell surface interactions at the vascular wall R-HSA-202733
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling downstream of RAS mutants R-HSA-9649948
Integrin signaling R-HSA-354192
Signaling by TGFB family members R-HSA-9006936
Non-integrin membrane-ECM interactions R-HSA-3000171
Hemostasis R-HSA-109582
VEGFA-VEGFR2 Pathway R-HSA-4420097
MAP2K and MAPK activation R-HSA-5674135
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
L1CAM interactions R-HSA-373760
Axon guidance R-HSA-422475
ECM proteoglycans R-HSA-3000178
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
PECAM1 interactions R-HSA-210990
Platelet activation, signaling and aggregation R-HSA-76002
Signal Transduction R-HSA-162582
p130Cas linkage to MAPK signaling for integrins R-HSA-372708
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
TGF-beta receptor signaling activates SMADs R-HSA-2173789
L1CAM interactions R-HSA-373760
Oncogenic MAPK signaling R-HSA-6802957
Signaling by RAS mutants R-HSA-6802949
Elastic fibre formation R-HSA-1566948
Nervous system development R-HSA-9675108
Signaling downstream of RAS mutants R-HSA-9649948
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAP2K and MAPK activation R-HSA-5674135
Developmental Biology R-HSA-1266738
VEGFA-VEGFR2 Pathway R-HSA-4420097
MAPK1/MAPK3 signaling R-HSA-5684996
Non-integrin membrane-ECM interactions R-HSA-3000171
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194
ECM proteoglycans R-HSA-3000178
Integrin signaling R-HSA-354192
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by TGFB family members R-HSA-9006936
Signaling by TGF-beta Receptor Complex R-HSA-170834
Extracellular matrix organization R-HSA-1474244
Platelet Aggregation (Plug Formation) R-HSA-76009
MAPK family signaling cascades R-HSA-5683057
Platelet degranulation R-HSA-114608
Signaling by VEGF R-HSA-194138
Hemostasis R-HSA-109582
Integrin cell surface interactions R-HSA-216083
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Molecules associated with elastic fibres R-HSA-2129379
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Syndecan interactions R-HSA-3000170
Signal transduction by L1 R-HSA-445144
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by RAF1 mutants R-HSA-9656223
Axon guidance R-HSA-422475
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RAF/MAP kinase cascade R-HSA-5673001
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by RAF1 mutants R-HSA-9656223
Molecules associated with elastic fibres R-HSA-2129379
Platelet Aggregation (Plug Formation) R-HSA-76009
Axon guidance R-HSA-422475
Non-integrin membrane-ECM interactions R-HSA-3000171
Disease R-HSA-1643685
Signaling by TGF-beta Receptor Complex R-HSA-170834
Integrin cell surface interactions R-HSA-216083
Cell surface interactions at the vascular wall R-HSA-202733
Oncogenic MAPK signaling R-HSA-6802957
ECM proteoglycans R-HSA-3000178
p130Cas linkage to MAPK signaling for integrins R-HSA-372708
MAPK family signaling cascades R-HSA-5683057
Signaling by RAS mutants R-HSA-6802949
Extracellular matrix organization R-HSA-1474244
MAPK1/MAPK3 signaling R-HSA-5684996
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194
Syndecan interactions R-HSA-3000170
Elastic fibre formation R-HSA-1566948
Platelet activation, signaling and aggregation R-HSA-76002
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PECAM1 interactions R-HSA-210990
Signaling by VEGF R-HSA-194138
Developmental Biology R-HSA-1266738
L1CAM interactions R-HSA-373760
Signaling by TGFB family members R-HSA-9006936
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by BRAF and RAF1 fusions R-HSA-6802952
MAP2K and MAPK activation R-HSA-5674135
Nervous system development R-HSA-9675108
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
TGF-beta receptor signaling activates SMADs R-HSA-2173789
RAF/MAP kinase cascade R-HSA-5673001
Platelet degranulation R-HSA-114608
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Hemostasis R-HSA-109582
Signal transduction by L1 R-HSA-445144
Integrin signaling R-HSA-354192
Signaling downstream of RAS mutants R-HSA-9649948
VEGFA-VEGFR2 Pathway R-HSA-4420097
L1CAM interactions R-HSA-373760
Extracellular matrix organization R-HSA-1474244
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
Hemostasis R-HSA-109582
Signaling by RAF1 mutants R-HSA-9656223
Signaling by RAS mutants R-HSA-6802949
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Platelet activation, signaling and aggregation R-HSA-76002
Integrin cell surface interactions R-HSA-216083
MAPK1/MAPK3 signaling R-HSA-5684996
Axon guidance R-HSA-422475
Platelet degranulation R-HSA-114608
p130Cas linkage to MAPK signaling for integrins R-HSA-372708
Non-integrin membrane-ECM interactions R-HSA-3000171
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
Signaling by VEGF R-HSA-194138
Signaling by TGF-beta Receptor Complex R-HSA-170834
Molecules associated with elastic fibres R-HSA-2129379
Integrin signaling R-HSA-354192
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
ECM proteoglycans R-HSA-3000178
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Platelet Aggregation (Plug Formation) R-HSA-76009
MAPK family signaling cascades R-HSA-5683057
Syndecan interactions R-HSA-3000170
Elastic fibre formation R-HSA-1566948
VEGFA-VEGFR2 Pathway R-HSA-4420097
Oncogenic MAPK signaling R-HSA-6802957
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194
Disease R-HSA-1643685
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Nervous system development R-HSA-9675108
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Cell surface interactions at the vascular wall R-HSA-202733
Signal transduction by L1 R-HSA-445144
Signaling downstream of RAS mutants R-HSA-9649948
MAP2K and MAPK activation R-HSA-5674135
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
PECAM1 interactions R-HSA-210990
TGF-beta receptor signaling activates SMADs R-HSA-2173789

Expression Atlas ENSG00000259207
LRG display in Ensembl gene LRG_481
NCBI gene (formerly Entrezgene) 3690
GeneCards 6156
HGNC Symbol HGNC:6156
MIM gene 173470
MIM morbid 619271
UniProtKB Gene Name Q16157
WikiGene 3690
Gene: RPL5
Ensembl ID : ENSG00000122406
Description: ribosomal protein L5
Gene Synonyms: L5,PPP1R135,UL18
4 APIs:
217 Possible Orthologues:

Eukaryotic Translation Elongation R-HSA-156842
Infectious disease R-HSA-5663205
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Selenocysteine synthesis R-HSA-2408557
Peptide chain elongation R-HSA-156902
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Eukaryotic Translation Termination R-HSA-72764
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
rRNA processing in the nucleus and cytosol R-HSA-8868773
rRNA processing R-HSA-72312
Selenoamino acid metabolism R-HSA-2408522
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Translation R-HSA-72766
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Viral mRNA Translation R-HSA-192823
Metabolism of proteins R-HSA-392499
Eukaryotic Translation Initiation R-HSA-72613
Cellular response to starvation R-HSA-9711097
Influenza Infection R-HSA-168255
Nonsense-Mediated Decay (NMD) R-HSA-927802
Nervous system development R-HSA-9675108
Signaling by ROBO receptors R-HSA-376176
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Influenza Viral RNA Transcription and Replication R-HSA-168273
Metabolism of amino acids and derivatives R-HSA-71291
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Cellular responses to stimuli R-HSA-8953897
Metabolism of RNA R-HSA-8953854
Formation of a pool of free 40S subunits R-HSA-72689
Metabolism R-HSA-1430728
Cap-dependent Translation Initiation R-HSA-72737
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Nonsense-Mediated Decay (NMD) R-HSA-927802
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Formation of a pool of free 40S subunits R-HSA-72689
Eukaryotic Translation Elongation R-HSA-156842
Cap-dependent Translation Initiation R-HSA-72737
rRNA processing in the nucleus and cytosol R-HSA-8868773
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Signaling by ROBO receptors R-HSA-376176
Disease R-HSA-1643685
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Cellular responses to stress R-HSA-2262752
Metabolism of amino acids and derivatives R-HSA-71291
Selenocysteine synthesis R-HSA-2408557
Eukaryotic Translation Initiation R-HSA-72613
Metabolism R-HSA-1430728
Metabolism of proteins R-HSA-392499
Influenza Infection R-HSA-168255
Peptide chain elongation R-HSA-156902
Nervous system development R-HSA-9675108
Viral mRNA Translation R-HSA-192823
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Infectious disease R-HSA-5663205
Metabolism of RNA R-HSA-8953854
Eukaryotic Translation Termination R-HSA-72764
Cellular responses to stimuli R-HSA-8953897
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Translation R-HSA-72766
Selenoamino acid metabolism R-HSA-2408522
rRNA processing R-HSA-72312
Influenza Viral RNA Transcription and Replication R-HSA-168273
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular response to starvation R-HSA-9711097
Nonsense-Mediated Decay (NMD) R-HSA-927802
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Formation of a pool of free 40S subunits R-HSA-72689
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
rRNA processing R-HSA-72312
Signaling by ROBO receptors R-HSA-376176
Axon guidance R-HSA-422475
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Cap-dependent Translation Initiation R-HSA-72737
Eukaryotic Translation Termination R-HSA-72764
rRNA processing in the nucleus and cytosol R-HSA-8868773
Peptide chain elongation R-HSA-156902
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
Selenocysteine synthesis R-HSA-2408557
Influenza Viral RNA Transcription and Replication R-HSA-168273
Selenoamino acid metabolism R-HSA-2408522
Translation R-HSA-72766
Cellular responses to stimuli R-HSA-8953897
Metabolism of RNA R-HSA-8953854
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Cellular responses to stress R-HSA-2262752
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Developmental Biology R-HSA-1266738
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Eukaryotic Translation Elongation R-HSA-156842
Cellular response to starvation R-HSA-9711097
Influenza Infection R-HSA-168255
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Viral mRNA Translation R-HSA-192823
Eukaryotic Translation Initiation R-HSA-72613
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Peptide chain elongation R-HSA-156902
rRNA processing R-HSA-72312
Metabolism of RNA R-HSA-8953854
Eukaryotic Translation Initiation R-HSA-72613
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Metabolism R-HSA-1430728
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Axon guidance R-HSA-422475
Eukaryotic Translation Termination R-HSA-72764
Formation of a pool of free 40S subunits R-HSA-72689
Signaling by ROBO receptors R-HSA-376176
Selenoamino acid metabolism R-HSA-2408522
Nervous system development R-HSA-9675108
Translation R-HSA-72766
Nonsense-Mediated Decay (NMD) R-HSA-927802
Viral mRNA Translation R-HSA-192823
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Influenza Viral RNA Transcription and Replication R-HSA-168273
rRNA processing in the nucleus and cytosol R-HSA-8868773
Metabolism of amino acids and derivatives R-HSA-71291
Cap-dependent Translation Initiation R-HSA-72737
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Selenocysteine synthesis R-HSA-2408557
Disease R-HSA-1643685
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular response to starvation R-HSA-9711097
Developmental Biology R-HSA-1266738
Influenza Infection R-HSA-168255
Cellular responses to stress R-HSA-2262752
Eukaryotic Translation Elongation R-HSA-156842
Metabolism of proteins R-HSA-392499
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Nonsense-Mediated Decay (NMD) R-HSA-927802
Cellular responses to stress R-HSA-2262752
Formation of a pool of free 40S subunits R-HSA-72689
Metabolism of amino acids and derivatives R-HSA-71291
Selenocysteine synthesis R-HSA-2408557
Viral mRNA Translation R-HSA-192823
Eukaryotic Translation Elongation R-HSA-156842
Cellular response to starvation R-HSA-9711097
Metabolism of RNA R-HSA-8953854
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Developmental Biology R-HSA-1266738
Selenoamino acid metabolism R-HSA-2408522
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
rRNA processing R-HSA-72312
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Cap-dependent Translation Initiation R-HSA-72737
Influenza Viral RNA Transcription and Replication R-HSA-168273
Cellular responses to stimuli R-HSA-8953897
Nervous system development R-HSA-9675108
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
rRNA processing in the nucleus and cytosol R-HSA-8868773
Eukaryotic Translation Initiation R-HSA-72613
Infectious disease R-HSA-5663205
Influenza Infection R-HSA-168255
Metabolism R-HSA-1430728
Axon guidance R-HSA-422475
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Translation R-HSA-72766
Peptide chain elongation R-HSA-156902
Eukaryotic Translation Termination R-HSA-72764
Signaling by ROBO receptors R-HSA-376176
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Cellular responses to stress R-HSA-2262752
Metabolism of proteins R-HSA-392499
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Cellular responses to stimuli R-HSA-8953897
Influenza Viral RNA Transcription and Replication R-HSA-168273
rRNA processing R-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Cap-dependent Translation Initiation R-HSA-72737
Metabolism of amino acids and derivatives R-HSA-71291
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Formation of a pool of free 40S subunits R-HSA-72689
Metabolism of RNA R-HSA-8953854
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Selenoamino acid metabolism R-HSA-2408522
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Translation R-HSA-72766
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Eukaryotic Translation Elongation R-HSA-156842
Axon guidance R-HSA-422475
rRNA processing in the nucleus and cytosol R-HSA-8868773
Nonsense-Mediated Decay (NMD) R-HSA-927802
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Selenocysteine synthesis R-HSA-2408557
Infectious disease R-HSA-5663205
Cellular response to starvation R-HSA-9711097
Eukaryotic Translation Initiation R-HSA-72613
Viral mRNA Translation R-HSA-192823
Developmental Biology R-HSA-1266738
Signaling by ROBO receptors R-HSA-376176
Influenza Infection R-HSA-168255
Nervous system development R-HSA-9675108
Peptide chain elongation R-HSA-156902
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Eukaryotic Translation Termination R-HSA-72764
Selenoamino acid metabolism R-HSA-2408522
Eukaryotic Translation Initiation R-HSA-72613
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Infectious disease R-HSA-5663205
Metabolism of proteins R-HSA-392499
rRNA processing R-HSA-72312
Developmental Biology R-HSA-1266738
Eukaryotic Translation Termination R-HSA-72764
Cellular responses to stimuli R-HSA-8953897
Metabolism of amino acids and derivatives R-HSA-71291
Influenza Infection R-HSA-168255
Formation of a pool of free 40S subunits R-HSA-72689
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Nervous system development R-HSA-9675108
Cellular responses to stress R-HSA-2262752
Nonsense-Mediated Decay (NMD) R-HSA-927802
Metabolism of RNA R-HSA-8953854
Selenocysteine synthesis R-HSA-2408557
Cap-dependent Translation Initiation R-HSA-72737
Peptide chain elongation R-HSA-156902
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Cellular response to starvation R-HSA-9711097
Signaling by ROBO receptors R-HSA-376176
Influenza Viral RNA Transcription and Replication R-HSA-168273
rRNA processing in the nucleus and cytosol R-HSA-8868773
Viral mRNA Translation R-HSA-192823
Eukaryotic Translation Elongation R-HSA-156842
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Translation R-HSA-72766
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Viral mRNA Translation R-HSA-192823
Metabolism of amino acids and derivatives R-HSA-71291
Translation R-HSA-72766
Nervous system development R-HSA-9675108
Metabolism of RNA R-HSA-8953854
Developmental Biology R-HSA-1266738
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cap-dependent Translation Initiation R-HSA-72737
Cellular responses to stimuli R-HSA-8953897
Influenza Infection R-HSA-168255
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Disease R-HSA-1643685
rRNA processing in the nucleus and cytosol R-HSA-8868773
Cellular responses to stress R-HSA-2262752
Eukaryotic Translation Elongation R-HSA-156842
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Eukaryotic Translation Initiation R-HSA-72613
Selenocysteine synthesis R-HSA-2408557
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Cellular response to starvation R-HSA-9711097
Signaling by ROBO receptors R-HSA-376176
Metabolism of proteins R-HSA-392499
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Selenoamino acid metabolism R-HSA-2408522
Influenza Viral RNA Transcription and Replication R-HSA-168273
Eukaryotic Translation Termination R-HSA-72764
Nonsense-Mediated Decay (NMD) R-HSA-927802
Infectious disease R-HSA-5663205
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Formation of a pool of free 40S subunits R-HSA-72689
Axon guidance R-HSA-422475
rRNA processing R-HSA-72312
Peptide chain elongation R-HSA-156902
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Peptide chain elongation R-HSA-156902
Cellular response to starvation R-HSA-9711097
Signaling by ROBO receptors R-HSA-376176
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Translation R-HSA-72766
Influenza Viral RNA Transcription and Replication R-HSA-168273
Formation of a pool of free 40S subunits R-HSA-72689
Axon guidance R-HSA-422475
Selenocysteine synthesis R-HSA-2408557
Developmental Biology R-HSA-1266738
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Eukaryotic Translation Initiation R-HSA-72613
Cellular responses to stress R-HSA-2262752
Nonsense-Mediated Decay (NMD) R-HSA-927802
Eukaryotic Translation Termination R-HSA-72764
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Cellular responses to stimuli R-HSA-8953897
Metabolism of proteins R-HSA-392499
Selenoamino acid metabolism R-HSA-2408522
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Regulation of expression of SLITs and ROBOs R-HSA-9010553
rRNA processing in the nucleus and cytosol R-HSA-8868773
Infectious disease R-HSA-5663205
rRNA processing R-HSA-72312
Influenza Infection R-HSA-168255
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Metabolism R-HSA-1430728
Viral mRNA Translation R-HSA-192823
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Cap-dependent Translation Initiation R-HSA-72737
Metabolism of RNA R-HSA-8953854
Eukaryotic Translation Elongation R-HSA-156842
Metabolism of amino acids and derivatives R-HSA-71291

Expression Atlas ENSG00000122406
LRG display in Ensembl gene LRG_1155
NCBI gene (formerly Entrezgene) 6125
GeneCards 10360
HGNC Symbol HGNC:10360
MIM gene 603634
MIM morbid 612561
UniProtKB Gene Name R4GNJ2
WikiGene 6125
Gene: PNP
Ensembl ID : ENSG00000198805
Description: purine nucleoside phosphorylase
Gene Synonyms: NP,PUNP
1 APIs:
123 Possible Orthologues:

Purine salvage R-HSA-74217
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism R-HSA-8956319
Neutrophil degranulation R-HSA-6798695
Nucleotide catabolism defects R-HSA-9735786
Innate Immune System R-HSA-168249
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Diseases of nucleotide metabolism R-HSA-9735804
Ribavirin ADME R-HSA-9755088
Drug ADME R-HSA-9748784
Immune System R-HSA-168256
Disease R-HSA-1643685
Diseases of metabolism R-HSA-5668914
Nucleotide salvage R-HSA-8956321
Metabolism R-HSA-1430728
Purine catabolism R-HSA-74259
Disease R-HSA-1643685
Metabolism R-HSA-1430728
Innate Immune System R-HSA-168249
Metabolism of nucleotides R-HSA-15869
Diseases of nucleotide metabolism R-HSA-9735804
Drug ADME R-HSA-9748784
Purine catabolism R-HSA-74259
Ribavirin ADME R-HSA-9755088
Neutrophil degranulation R-HSA-6798695
Nucleotide catabolism defects R-HSA-9735786
Immune System R-HSA-168256
Nucleotide catabolism R-HSA-8956319
Nucleotide salvage R-HSA-8956321
Diseases of metabolism R-HSA-5668914
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Purine salvage R-HSA-74217
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Metabolism R-HSA-1430728
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Disease R-HSA-1643685
Nucleotide catabolism R-HSA-8956319
Nucleotide catabolism defects R-HSA-9735786
Purine catabolism R-HSA-74259
Diseases of metabolism R-HSA-5668914
Innate Immune System R-HSA-168249
Metabolism of nucleotides R-HSA-15869
Purine salvage R-HSA-74217
Nucleotide salvage R-HSA-8956321
Drug ADME R-HSA-9748784
Diseases of nucleotide metabolism R-HSA-9735804
Ribavirin ADME R-HSA-9755088
Disease R-HSA-1643685
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism defects R-HSA-9735786
Drug ADME R-HSA-9748784
Innate Immune System R-HSA-168249
Metabolism R-HSA-1430728
Diseases of nucleotide metabolism R-HSA-9735804
Immune System R-HSA-168256
Ribavirin ADME R-HSA-9755088
Purine catabolism R-HSA-74259
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Nucleotide catabolism R-HSA-8956319
Neutrophil degranulation R-HSA-6798695
Nucleotide salvage R-HSA-8956321
Diseases of metabolism R-HSA-5668914
Purine salvage R-HSA-74217
Nucleotide catabolism defects R-HSA-9735786
Disease R-HSA-1643685
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Ribavirin ADME R-HSA-9755088
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism R-HSA-8956319
Nucleotide salvage R-HSA-8956321
Innate Immune System R-HSA-168249
Diseases of metabolism R-HSA-5668914
Purine salvage R-HSA-74217
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Purine catabolism R-HSA-74259
Diseases of nucleotide metabolism R-HSA-9735804
Metabolism R-HSA-1430728
Drug ADME R-HSA-9748784
Innate Immune System R-HSA-168249
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Ribavirin ADME R-HSA-9755088
Purine catabolism R-HSA-74259
Metabolism R-HSA-1430728
Purine salvage R-HSA-74217
Nucleotide catabolism defects R-HSA-9735786
Immune System R-HSA-168256
Diseases of nucleotide metabolism R-HSA-9735804
Disease R-HSA-1643685
Nucleotide salvage R-HSA-8956321
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Drug ADME R-HSA-9748784
Diseases of metabolism R-HSA-5668914
Neutrophil degranulation R-HSA-6798695
Disease R-HSA-1643685
Metabolism of nucleotides R-HSA-15869
Nucleotide salvage R-HSA-8956321
Purine catabolism R-HSA-74259
Metabolism R-HSA-1430728
Drug ADME R-HSA-9748784
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Diseases of metabolism R-HSA-5668914
Ribavirin ADME R-HSA-9755088
Innate Immune System R-HSA-168249
Nucleotide catabolism defects R-HSA-9735786
Purine salvage R-HSA-74217
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Diseases of nucleotide metabolism R-HSA-9735804
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Purine salvage R-HSA-74217
Nucleotide catabolism defects R-HSA-9735786
Ribavirin ADME R-HSA-9755088
Metabolism R-HSA-1430728
Purine catabolism R-HSA-74259
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Drug ADME R-HSA-9748784
Diseases of nucleotide metabolism R-HSA-9735804
Diseases of metabolism R-HSA-5668914
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Nucleotide catabolism R-HSA-8956319
Nucleotide salvage R-HSA-8956321

Expression Atlas ENSG00000198805
LRG display in Ensembl gene LRG_91
NCBI gene (formerly Entrezgene) 4860
GeneCards 7892
HGNC Symbol HGNC:7892
MIM gene 164050
MIM morbid 613179
UniProtKB Gene Name V9HWH6
WikiGene 4860
Gene: IMPDH1
Ensembl ID : ENSG00000106348
Description: inosine monophosphate dehydrogenase 1
Gene Synonyms: LCA11,RP10,SWSS2608
8 APIs:
271 Possible Orthologues:

Drug ADME R-HSA-9748784
Metabolism R-HSA-1430728
Infectious disease R-HSA-5663205
Innate Immune System R-HSA-168249
SARS-CoV Infections R-HSA-9679506
Azathioprine ADME R-HSA-9748787
Neutrophil degranulation R-HSA-6798695
Disease R-HSA-1643685
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817
Nucleotide biosynthesis R-HSA-8956320
Immune System R-HSA-168256
Potential therapeutics for SARS R-HSA-9679191
Metabolism of nucleotides R-HSA-15869
Nucleotide biosynthesis R-HSA-8956320
Infectious disease R-HSA-5663205
Metabolism of nucleotides R-HSA-15869
Disease R-HSA-1643685
Metabolism R-HSA-1430728
Innate Immune System R-HSA-168249
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817
SARS-CoV Infections R-HSA-9679506
Potential therapeutics for SARS R-HSA-9679191
Immune System R-HSA-168256
Azathioprine ADME R-HSA-9748787
Neutrophil degranulation R-HSA-6798695
Drug ADME R-HSA-9748784
Azathioprine ADME R-HSA-9748787
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817
Nucleotide biosynthesis R-HSA-8956320
SARS-CoV Infections R-HSA-9679506
Immune System R-HSA-168256
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Drug ADME R-HSA-9748784
Metabolism R-HSA-1430728
Potential therapeutics for SARS R-HSA-9679191
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Metabolism of nucleotides R-HSA-15869
SARS-CoV Infections R-HSA-9679506
Azathioprine ADME R-HSA-9748787
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817
Metabolism R-HSA-1430728
Immune System R-HSA-168256
Drug ADME R-HSA-9748784
Nucleotide biosynthesis R-HSA-8956320
Metabolism of nucleotides R-HSA-15869
Neutrophil degranulation R-HSA-6798695
Potential therapeutics for SARS R-HSA-9679191
Azathioprine ADME R-HSA-9748787
Neutrophil degranulation R-HSA-6798695
Metabolism of nucleotides R-HSA-15869
Immune System R-HSA-168256
Nucleotide biosynthesis R-HSA-8956320
Disease R-HSA-1643685
Drug ADME R-HSA-9748784
Innate Immune System R-HSA-168249
Metabolism R-HSA-1430728
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817
Potential therapeutics for SARS R-HSA-9679191
Infectious disease R-HSA-5663205
SARS-CoV Infections R-HSA-9679506
Metabolism of nucleotides R-HSA-15869
Infectious disease R-HSA-5663205
Metabolism R-HSA-1430728
Innate Immune System R-HSA-168249
Nucleotide biosynthesis R-HSA-8956320
SARS-CoV Infections R-HSA-9679506
Azathioprine ADME R-HSA-9748787
Neutrophil degranulation R-HSA-6798695
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817
Disease R-HSA-1643685
Potential therapeutics for SARS R-HSA-9679191
Drug ADME R-HSA-9748784
Immune System R-HSA-168256
Metabolism R-HSA-1430728
Potential therapeutics for SARS R-HSA-9679191
Infectious disease R-HSA-5663205
Nucleotide biosynthesis R-HSA-8956320
SARS-CoV Infections R-HSA-9679506
Neutrophil degranulation R-HSA-6798695
Drug ADME R-HSA-9748784
Innate Immune System R-HSA-168249
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817
Azathioprine ADME R-HSA-9748787
Metabolism of nucleotides R-HSA-15869
Immune System R-HSA-168256
Disease R-HSA-1643685
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Potential therapeutics for SARS R-HSA-9679191
Metabolism R-HSA-1430728
Infectious disease R-HSA-5663205
SARS-CoV Infections R-HSA-9679506
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817
Drug ADME R-HSA-9748784
Azathioprine ADME R-HSA-9748787
Metabolism of nucleotides R-HSA-15869
Disease R-HSA-1643685
Immune System R-HSA-168256
Nucleotide biosynthesis R-HSA-8956320
Immune System R-HSA-168256
Nucleotide biosynthesis R-HSA-8956320
Disease R-HSA-1643685
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Azathioprine ADME R-HSA-9748787
Metabolism of nucleotides R-HSA-15869
Potential therapeutics for SARS R-HSA-9679191
Drug ADME R-HSA-9748784
Infectious disease R-HSA-5663205
Metabolism R-HSA-1430728
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
Potential therapeutics for SARS R-HSA-9679191
Immune System R-HSA-168256
SARS-CoV Infections R-HSA-9679506
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817
Metabolism R-HSA-1430728
Neutrophil degranulation R-HSA-6798695
Azathioprine ADME R-HSA-9748787
Innate Immune System R-HSA-168249
Drug ADME R-HSA-9748784
Infectious disease R-HSA-5663205
Nucleotide biosynthesis R-HSA-8956320
Metabolism of nucleotides R-HSA-15869
Immune System R-HSA-168256
SARS-CoV Infections R-HSA-9679506
Potential therapeutics for SARS R-HSA-9679191
Drug ADME R-HSA-9748784
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Innate Immune System R-HSA-168249
Nucleotide biosynthesis R-HSA-8956320
Metabolism of nucleotides R-HSA-15869
Neutrophil degranulation R-HSA-6798695
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817
Metabolism R-HSA-1430728
Azathioprine ADME R-HSA-9748787

Expression Atlas ENSG00000106348
NCBI gene (formerly Entrezgene) 3614
GeneCards 6052
HGNC Symbol HGNC:6052
MIM gene 146690
MIM morbid 613837
UniProtKB Gene Name F8WDE9
WikiGene 3614
Gene: RPL7
Ensembl ID : ENSG00000147604
Description: ribosomal protein L7
Gene Synonyms: HUML7-1,L7
4 APIs:
334 Possible Orthologues:

Translation R-HSA-72766
Influenza Viral RNA Transcription and Replication R-HSA-168273
Formation of a pool of free 40S subunits R-HSA-72689
Cap-dependent Translation Initiation R-HSA-72737
Translation R-HSA-72766
Developmental Biology R-HSA-1266738
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Metabolism of RNA R-HSA-8953854
Eukaryotic Translation Termination R-HSA-72764
Viral mRNA Translation R-HSA-192823
Influenza Infection R-HSA-168255
Infectious disease R-HSA-5663205
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
rRNA processing in the nucleus and cytosol R-HSA-8868773
Eukaryotic Translation Initiation R-HSA-72613
Signaling by ROBO receptors R-HSA-376176
Nonsense-Mediated Decay (NMD) R-HSA-927802
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Cellular responses to stimuli R-HSA-8953897
Eukaryotic Translation Elongation R-HSA-156842
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Axon guidance R-HSA-422475
Selenocysteine synthesis R-HSA-2408557
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Peptide chain elongation R-HSA-156902
Disease R-HSA-1643685
rRNA processing R-HSA-72312
Selenoamino acid metabolism R-HSA-2408522
Cellular response to starvation R-HSA-9711097
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Metabolism of amino acids and derivatives R-HSA-71291
Selenocysteine synthesis R-HSA-2408557
Axon guidance R-HSA-422475
Regulation of expression of SLITs and ROBOs R-HSA-9010553
rRNA processing R-HSA-72312
Cellular response to starvation R-HSA-9711097
Disease R-HSA-1643685
Cellular responses to stimuli R-HSA-8953897
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Influenza Infection R-HSA-168255
Nervous system development R-HSA-9675108
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Peptide chain elongation R-HSA-156902
Nonsense-Mediated Decay (NMD) R-HSA-927802
Metabolism of proteins R-HSA-392499
Influenza Viral RNA Transcription and Replication R-HSA-168273
Developmental Biology R-HSA-1266738
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Cap-dependent Translation Initiation R-HSA-72737
Cellular responses to stress R-HSA-2262752
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Infectious disease R-HSA-5663205
rRNA processing in the nucleus and cytosol R-HSA-8868773
Signaling by ROBO receptors R-HSA-376176
Viral mRNA Translation R-HSA-192823
Selenoamino acid metabolism R-HSA-2408522
Translation R-HSA-72766
Formation of a pool of free 40S subunits R-HSA-72689
Eukaryotic Translation Initiation R-HSA-72613
Eukaryotic Translation Termination R-HSA-72764
Eukaryotic Translation Elongation R-HSA-156842
Metabolism of RNA R-HSA-8953854
Metabolism R-HSA-1430728
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
rRNA processing R-HSA-72312
Eukaryotic Translation Initiation R-HSA-72613
Selenoamino acid metabolism R-HSA-2408522
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
rRNA processing in the nucleus and cytosol R-HSA-8868773
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Disease R-HSA-1643685
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Translation R-HSA-72766
Formation of a pool of free 40S subunits R-HSA-72689
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Cap-dependent Translation Initiation R-HSA-72737
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Signaling by ROBO receptors R-HSA-376176
Metabolism of RNA R-HSA-8953854
Influenza Viral RNA Transcription and Replication R-HSA-168273
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Peptide chain elongation R-HSA-156902
Selenocysteine synthesis R-HSA-2408557
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Regulation of expression of SLITs and ROBOs R-HSA-9010553
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Eukaryotic Translation Elongation R-HSA-156842
Cellular response to starvation R-HSA-9711097
Nonsense-Mediated Decay (NMD) R-HSA-927802
Developmental Biology R-HSA-1266738
Metabolism of amino acids and derivatives R-HSA-71291
Viral mRNA Translation R-HSA-192823
Metabolism R-HSA-1430728
Influenza Infection R-HSA-168255
Eukaryotic Translation Termination R-HSA-72764
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Influenza Infection R-HSA-168255
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Axon guidance R-HSA-422475
Metabolism of proteins R-HSA-392499
Nonsense-Mediated Decay (NMD) R-HSA-927802
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
rRNA processing in the nucleus and cytosol R-HSA-8868773
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Cellular responses to stimuli R-HSA-8953897
Eukaryotic Translation Initiation R-HSA-72613
Cellular response to starvation R-HSA-9711097
Cap-dependent Translation Initiation R-HSA-72737
Peptide chain elongation R-HSA-156902
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Formation of a pool of free 40S subunits R-HSA-72689
Selenoamino acid metabolism R-HSA-2408522
Cellular responses to stress R-HSA-2262752
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
Infectious disease R-HSA-5663205
rRNA processing R-HSA-72312
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Eukaryotic Translation Elongation R-HSA-156842
Eukaryotic Translation Termination R-HSA-72764
Selenocysteine synthesis R-HSA-2408557
Viral mRNA Translation R-HSA-192823
Metabolism of RNA R-HSA-8953854
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Influenza Viral RNA Transcription and Replication R-HSA-168273
Translation R-HSA-72766
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Signaling by ROBO receptors R-HSA-376176
Developmental Biology R-HSA-1266738
Metabolism of RNA R-HSA-8953854
Eukaryotic Translation Elongation R-HSA-156842
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cap-dependent Translation Initiation R-HSA-72737
Axon guidance R-HSA-422475
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
Selenoamino acid metabolism R-HSA-2408522
Eukaryotic Translation Termination R-HSA-72764
Influenza Infection R-HSA-168255
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Metabolism R-HSA-1430728
Eukaryotic Translation Initiation R-HSA-72613
Cellular response to starvation R-HSA-9711097
Selenocysteine synthesis R-HSA-2408557
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Infectious disease R-HSA-5663205
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Signaling by ROBO receptors R-HSA-376176
Nonsense-Mediated Decay (NMD) R-HSA-927802
Influenza Viral RNA Transcription and Replication R-HSA-168273
Cellular responses to stress R-HSA-2262752
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Formation of a pool of free 40S subunits R-HSA-72689
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Peptide chain elongation R-HSA-156902
Cellular responses to stimuli R-HSA-8953897
Viral mRNA Translation R-HSA-192823
rRNA processing R-HSA-72312
rRNA processing in the nucleus and cytosol R-HSA-8868773
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Metabolism R-HSA-1430728
Formation of a pool of free 40S subunits R-HSA-72689
Cellular responses to stimuli R-HSA-8953897
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Disease R-HSA-1643685
Metabolism of amino acids and derivatives R-HSA-71291
Influenza Viral RNA Transcription and Replication R-HSA-168273
Infectious disease R-HSA-5663205
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Viral mRNA Translation R-HSA-192823
rRNA processing R-HSA-72312
Axon guidance R-HSA-422475
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Metabolism of RNA R-HSA-8953854
Cellular response to starvation R-HSA-9711097
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Eukaryotic Translation Elongation R-HSA-156842
Selenocysteine synthesis R-HSA-2408557
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Eukaryotic Translation Initiation R-HSA-72613
Metabolism of proteins R-HSA-392499
Selenoamino acid metabolism R-HSA-2408522
Eukaryotic Translation Termination R-HSA-72764
rRNA processing in the nucleus and cytosol R-HSA-8868773
Cap-dependent Translation Initiation R-HSA-72737
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Nonsense-Mediated Decay (NMD) R-HSA-927802
Influenza Infection R-HSA-168255
Translation R-HSA-72766
Peptide chain elongation R-HSA-156902
Developmental Biology R-HSA-1266738
Signaling by ROBO receptors R-HSA-376176
Viral mRNA Translation R-HSA-192823
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Cellular responses to stress R-HSA-2262752
Nonsense-Mediated Decay (NMD) R-HSA-927802
Cellular responses to stimuli R-HSA-8953897
Metabolism of RNA R-HSA-8953854
Axon guidance R-HSA-422475
Influenza Infection R-HSA-168255
Selenoamino acid metabolism R-HSA-2408522
Peptide chain elongation R-HSA-156902
rRNA processing in the nucleus and cytosol R-HSA-8868773
Nervous system development R-HSA-9675108
Cellular response to starvation R-HSA-9711097
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Signaling by ROBO receptors R-HSA-376176
rRNA processing R-HSA-72312
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Eukaryotic Translation Elongation R-HSA-156842
Formation of a pool of free 40S subunits R-HSA-72689
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Influenza Viral RNA Transcription and Replication R-HSA-168273
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Translation R-HSA-72766
Cap-dependent Translation Initiation R-HSA-72737
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism R-HSA-1430728
Metabolism of proteins R-HSA-392499
Eukaryotic Translation Initiation R-HSA-72613
Selenocysteine synthesis R-HSA-2408557
Eukaryotic Translation Termination R-HSA-72764
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Developmental Biology R-HSA-1266738
Selenoamino acid metabolism R-HSA-2408522
rRNA processing in the nucleus and cytosol R-HSA-8868773
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Metabolism R-HSA-1430728
rRNA processing R-HSA-72312
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Influenza Infection R-HSA-168255
Cap-dependent Translation Initiation R-HSA-72737
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Metabolism of RNA R-HSA-8953854
Metabolism of amino acids and derivatives R-HSA-71291
Formation of a pool of free 40S subunits R-HSA-72689
Selenocysteine synthesis R-HSA-2408557
Eukaryotic Translation Elongation R-HSA-156842
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Regulation of expression of SLITs and ROBOs R-HSA-9010553
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
Eukaryotic Translation Termination R-HSA-72764
Signaling by ROBO receptors R-HSA-376176
Cellular response to starvation R-HSA-9711097
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Nonsense-Mediated Decay (NMD) R-HSA-927802
Eukaryotic Translation Initiation R-HSA-72613
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Infectious disease R-HSA-5663205
Translation R-HSA-72766
Influenza Viral RNA Transcription and Replication R-HSA-168273
Peptide chain elongation R-HSA-156902
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
Viral mRNA Translation R-HSA-192823
Cellular responses to stress R-HSA-2262752
Eukaryotic Translation Elongation R-HSA-156842
Influenza Infection R-HSA-168255
Metabolism of RNA R-HSA-8953854
Eukaryotic Translation Initiation R-HSA-72613
rRNA processing R-HSA-72312
Developmental Biology R-HSA-1266738
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Signaling by ROBO receptors R-HSA-376176
Formation of a pool of free 40S subunits R-HSA-72689
Viral mRNA Translation R-HSA-192823
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Nervous system development R-HSA-9675108
Metabolism of amino acids and derivatives R-HSA-71291
Cap-dependent Translation Initiation R-HSA-72737
Disease R-HSA-1643685
Cellular responses to stimuli R-HSA-8953897
Metabolism of proteins R-HSA-392499
rRNA processing in the nucleus and cytosol R-HSA-8868773
Eukaryotic Translation Termination R-HSA-72764
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Selenoamino acid metabolism R-HSA-2408522
Infectious disease R-HSA-5663205
Regulation of expression of SLITs and ROBOs R-HSA-9010553
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Metabolism R-HSA-1430728
Peptide chain elongation R-HSA-156902
Nonsense-Mediated Decay (NMD) R-HSA-927802
Selenocysteine synthesis R-HSA-2408557
Influenza Viral RNA Transcription and Replication R-HSA-168273
Translation R-HSA-72766
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Cellular response to starvation R-HSA-9711097
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Infectious disease R-HSA-5663205
rRNA processing in the nucleus and cytosol R-HSA-8868773
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Axon guidance R-HSA-422475
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by ROBO receptors R-HSA-376176
Influenza Viral RNA Transcription and Replication R-HSA-168273
Nonsense-Mediated Decay (NMD) R-HSA-927802
Metabolism of RNA R-HSA-8953854
rRNA processing R-HSA-72312
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Peptide chain elongation R-HSA-156902
Selenoamino acid metabolism R-HSA-2408522
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Metabolism of proteins R-HSA-392499
Translation R-HSA-72766
Developmental Biology R-HSA-1266738
Eukaryotic Translation Elongation R-HSA-156842
Influenza Infection R-HSA-168255
Nervous system development R-HSA-9675108
Eukaryotic Translation Termination R-HSA-72764
Cap-dependent Translation Initiation R-HSA-72737
Eukaryotic Translation Initiation R-HSA-72613
Formation of a pool of free 40S subunits R-HSA-72689
Cellular response to starvation R-HSA-9711097
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Selenocysteine synthesis R-HSA-2408557
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Disease R-HSA-1643685
Viral mRNA Translation R-HSA-192823
Cellular response to starvation R-HSA-9711097
Influenza Infection R-HSA-168255
Selenocysteine synthesis R-HSA-2408557
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
Viral mRNA Translation R-HSA-192823
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
rRNA processing R-HSA-72312
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
rRNA processing in the nucleus and cytosol R-HSA-8868773
Signaling by ROBO receptors R-HSA-376176
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
Cap-dependent Translation Initiation R-HSA-72737
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Disease R-HSA-1643685
Metabolism of amino acids and derivatives R-HSA-71291
Influenza Viral RNA Transcription and Replication R-HSA-168273
Metabolism R-HSA-1430728
Cellular responses to stress R-HSA-2262752
Infectious disease R-HSA-5663205
Peptide chain elongation R-HSA-156902
Nonsense-Mediated Decay (NMD) R-HSA-927802
Formation of a pool of free 40S subunits R-HSA-72689
Axon guidance R-HSA-422475
Eukaryotic Translation Elongation R-HSA-156842
Metabolism of RNA R-HSA-8953854
Translation R-HSA-72766
Selenoamino acid metabolism R-HSA-2408522
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Eukaryotic Translation Initiation R-HSA-72613
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Eukaryotic Translation Termination R-HSA-72764

Expression Atlas ENSG00000147604
NCBI gene (formerly Entrezgene) 6129
GeneCards 10363
HGNC Symbol HGNC:10363
MIM gene 604166
UniProtKB Gene Name P18124
WikiGene 6129
Gene: SPHK2
Ensembl ID : ENSG00000063176
Description: sphingosine kinase 2
Gene Synonyms:
1 APIs:
209 Possible Orthologues:

Sphingolipid metabolism R-HSA-428157
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Sphingolipid de novo biosynthesis R-HSA-1660661
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Sphingolipid metabolism R-HSA-428157
Sphingolipid de novo biosynthesis R-HSA-1660661
Sphingolipid metabolism R-HSA-428157
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Sphingolipid de novo biosynthesis R-HSA-1660661
Sphingolipid metabolism R-HSA-428157
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Sphingolipid de novo biosynthesis R-HSA-1660661
Sphingolipid de novo biosynthesis R-HSA-1660661
Metabolism of lipids R-HSA-556833
Sphingolipid metabolism R-HSA-428157
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Sphingolipid metabolism R-HSA-428157
Sphingolipid de novo biosynthesis R-HSA-1660661
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Sphingolipid de novo biosynthesis R-HSA-1660661
Metabolism of lipids R-HSA-556833
Sphingolipid metabolism R-HSA-428157
Metabolism R-HSA-1430728
Sphingolipid metabolism R-HSA-428157
Metabolism of lipids R-HSA-556833
Sphingolipid de novo biosynthesis R-HSA-1660661
Metabolism R-HSA-1430728
Sphingolipid de novo biosynthesis R-HSA-1660661
Sphingolipid metabolism R-HSA-428157
Metabolism of lipids R-HSA-556833
Sphingolipid metabolism R-HSA-428157
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Sphingolipid de novo biosynthesis R-HSA-1660661

Expression Atlas ENSG00000063176
NCBI gene (formerly Entrezgene) 56848
GeneCards 18859
HGNC Symbol HGNC:18859
MIM gene 607092
UniProtKB Gene Name Q9NRA0
WikiGene 56848
Gene: NOTCH1
Ensembl ID : ENSG00000148400
Description: notch receptor 1
Gene Synonyms: TAN1
1 APIs:
269 Possible Orthologues:

Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Cellular response to chemical stress R-HSA-9711123
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
RUNX3 regulates NOTCH signaling R-HSA-8941856
Pre-NOTCH Expression and Processing R-HSA-1912422
Cellular response to chemical stress R-HSA-9711123
Diseases associated with O-glycosylation of proteins R-HSA-3906995
Formation of paraxial mesoderm R-HSA-9793380
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Pre-NOTCH Processing in Golgi R-HSA-1912420
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826
MECP2 regulates neuronal receptors and channels R-HSA-9022699
RNA Polymerase II Transcription R-HSA-73857
Regulation of beta-cell development R-HSA-186712
Transcriptional Regulation by MECP2 R-HSA-8986944
Gastrulation R-HSA-9758941
Notch-HLH transcription pathway R-HSA-350054
Cellular responses to stress R-HSA-2262752
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
Diseases of metabolism R-HSA-5668914
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 in Cancer R-HSA-2644603
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
Generic Transcription Pathway R-HSA-212436
Regulation of NFE2L2 gene expression R-HSA-9818749
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Gene expression (Transcription) R-HSA-74160
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399
Pre-NOTCH Transcription and Translation R-HSA-1912408
Signaling by NOTCH R-HSA-157118
Cellular responses to stimuli R-HSA-8953897
Signaling by NOTCH3 R-HSA-9012852
Defective LFNG causes SCDO3 R-HSA-5083630
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508
Diseases of glycosylation R-HSA-3781865
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607
Signaling by NOTCH3 R-HSA-9012852
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Diseases associated with O-glycosylation of proteins R-HSA-3906995
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 in Cancer R-HSA-2644603
Diseases of glycosylation R-HSA-3781865
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Gene expression (Transcription) R-HSA-74160
Cellular responses to stimuli R-HSA-8953897
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
Signal Transduction R-HSA-162582
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Cellular response to chemical stress R-HSA-9711123
Regulation of NFE2L2 gene expression R-HSA-9818749
Pre-NOTCH Expression and Processing R-HSA-1912422
RNA Polymerase II Transcription R-HSA-73857
Gastrulation R-HSA-9758941
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825
Defective LFNG causes SCDO3 R-HSA-5083630
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Transcriptional Regulation by MECP2 R-HSA-8986944
Pre-NOTCH Processing in Golgi R-HSA-1912420
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605
Signaling by NOTCH4 R-HSA-9013694
Formation of paraxial mesoderm R-HSA-9793380
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826
Regulation of beta-cell development R-HSA-186712
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX3 R-HSA-8878159
RUNX3 regulates NOTCH signaling R-HSA-8941856
Pre-NOTCH Transcription and Translation R-HSA-1912408
KEAP1-NFE2L2 pathway R-HSA-9755511
Disease R-HSA-1643685
Diseases of metabolism R-HSA-5668914
Notch-HLH transcription pathway R-HSA-350054
Cellular responses to stress R-HSA-2262752
RUNX3 regulates NOTCH signaling R-HSA-8941856
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508
Regulation of NFE2L2 gene expression R-HSA-9818749
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744
Signaling by NOTCH3 R-HSA-9012852
Diseases associated with O-glycosylation of proteins R-HSA-3906995
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399
Pre-NOTCH Transcription and Translation R-HSA-1912408
Formation of paraxial mesoderm R-HSA-9793380
Defective LFNG causes SCDO3 R-HSA-5083630
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Diseases of glycosylation R-HSA-3781865
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
Signaling by NOTCH1 in Cancer R-HSA-2644603
Gene expression (Transcription) R-HSA-74160
Cellular response to chemical stress R-HSA-9711123
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Gastrulation R-HSA-9758941
Regulation of beta-cell development R-HSA-186712
Transcriptional regulation by RUNX3 R-HSA-8878159
Notch-HLH transcription pathway R-HSA-350054
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605
Developmental Biology R-HSA-1266738
Transcriptional Regulation by MECP2 R-HSA-8986944
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826
Pre-NOTCH Processing in Golgi R-HSA-1912420
Pre-NOTCH Expression and Processing R-HSA-1912422
RNA Polymerase II Transcription R-HSA-73857
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Nuclear events mediated by NFE2L2 R-HSA-9759194
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Diseases of metabolism R-HSA-5668914
MECP2 regulates neuronal receptors and channels R-HSA-9022699
KEAP1-NFE2L2 pathway R-HSA-9755511
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607
Gastrulation R-HSA-9758941
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH1 R-HSA-1980143
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Pre-NOTCH Transcription and Translation R-HSA-1912408
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744
Signaling by NOTCH1 in Cancer R-HSA-2644603
Cellular responses to stimuli R-HSA-8953897
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
Generic Transcription Pathway R-HSA-212436
Defective LFNG causes SCDO3 R-HSA-5083630
Developmental Biology R-HSA-1266738
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Diseases of metabolism R-HSA-5668914
Transcriptional Regulation by MECP2 R-HSA-8986944
Diseases of glycosylation R-HSA-3781865
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605
Notch-HLH transcription pathway R-HSA-350054
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by NOTCH R-HSA-157118
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508
RNA Polymerase II Transcription R-HSA-73857
Regulation of beta-cell development R-HSA-186712
Regulation of NFE2L2 gene expression R-HSA-9818749
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Pre-NOTCH Expression and Processing R-HSA-1912422
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Formation of paraxial mesoderm R-HSA-9793380
Signaling by NOTCH3 R-HSA-9012852
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stress R-HSA-2262752
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Diseases associated with O-glycosylation of proteins R-HSA-3906995
RUNX3 regulates NOTCH signaling R-HSA-8941856
Pre-NOTCH Processing in Golgi R-HSA-1912420
Notch-HLH transcription pathway R-HSA-350054
Signaling by NOTCH1 R-HSA-1980143
KEAP1-NFE2L2 pathway R-HSA-9755511
RNA Polymerase II Transcription R-HSA-73857
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825
Gastrulation R-HSA-9758941
Cellular responses to stimuli R-HSA-8953897
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Regulation of beta-cell development R-HSA-186712
Pre-NOTCH Transcription and Translation R-HSA-1912408
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Transcriptional regulation by RUNX3 R-HSA-8878159
Diseases of metabolism R-HSA-5668914
Transcriptional Regulation by MECP2 R-HSA-8986944
Diseases associated with O-glycosylation of proteins R-HSA-3906995
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744
Pre-NOTCH Processing in Golgi R-HSA-1912420
Cellular responses to stress R-HSA-2262752
Diseases of glycosylation R-HSA-3781865
Regulation of NFE2L2 gene expression R-HSA-9818749
Pre-NOTCH Expression and Processing R-HSA-1912422
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nuclear events mediated by NFE2L2 R-HSA-9759194
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826
Signaling by NOTCH4 R-HSA-9013694
Cellular response to chemical stress R-HSA-9711123
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
RUNX3 regulates NOTCH signaling R-HSA-8941856
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Formation of paraxial mesoderm R-HSA-9793380
Gene expression (Transcription) R-HSA-74160
MECP2 regulates neuronal receptors and channels R-HSA-9022699
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH3 R-HSA-9012852
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605
Defective LFNG causes SCDO3 R-HSA-5083630
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508
Generic Transcription Pathway R-HSA-212436
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 in Cancer R-HSA-2644603
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
Pre-NOTCH Transcription and Translation R-HSA-1912408
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Cellular response to chemical stress R-HSA-9711123
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Diseases of metabolism R-HSA-5668914
Signaling by NOTCH R-HSA-157118
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Defective LFNG causes SCDO3 R-HSA-5083630
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Cellular responses to stimuli R-HSA-8953897
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744
Notch-HLH transcription pathway R-HSA-350054
Cellular responses to stress R-HSA-2262752
Formation of paraxial mesoderm R-HSA-9793380
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of NFE2L2 gene expression R-HSA-9818749
Regulation of beta-cell development R-HSA-186712
Diseases associated with O-glycosylation of proteins R-HSA-3906995
Gastrulation R-HSA-9758941
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508
Signal Transduction R-HSA-162582
Signaling by NOTCH1 R-HSA-1980143
Pre-NOTCH Expression and Processing R-HSA-1912422
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605
RUNX3 regulates NOTCH signaling R-HSA-8941856
Diseases of glycosylation R-HSA-3781865
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH3 R-HSA-9012852
RNA Polymerase II Transcription R-HSA-73857
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Pre-NOTCH Processing in Golgi R-HSA-1912420
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607
Transcriptional Regulation by MECP2 R-HSA-8986944
Signaling by NOTCH1 in Cancer R-HSA-2644603
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
KEAP1-NFE2L2 pathway R-HSA-9755511
KEAP1-NFE2L2 pathway R-HSA-9755511
Diseases associated with O-glycosylation of proteins R-HSA-3906995
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 in Cancer R-HSA-2644603
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Defective LFNG causes SCDO3 R-HSA-5083630
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744
Notch-HLH transcription pathway R-HSA-350054
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Signaling by NOTCH3 R-HSA-9012852
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508
Signal Transduction R-HSA-162582
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Pre-NOTCH Expression and Processing R-HSA-1912422
Gastrulation R-HSA-9758941
Cellular responses to stress R-HSA-2262752
Transcriptional Regulation by MECP2 R-HSA-8986944
Regulation of beta-cell development R-HSA-186712
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX3 R-HSA-8878159
Developmental Biology R-HSA-1266738
RUNX3 regulates NOTCH signaling R-HSA-8941856
RNA Polymerase II Transcription R-HSA-73857
Regulation of NFE2L2 gene expression R-HSA-9818749
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Pre-NOTCH Processing in Golgi R-HSA-1912420
Pre-NOTCH Transcription and Translation R-HSA-1912408
Diseases of metabolism R-HSA-5668914
Diseases of glycosylation R-HSA-3781865
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Nuclear events mediated by NFE2L2 R-HSA-9759194
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399
Formation of paraxial mesoderm R-HSA-9793380
Diseases of glycosylation R-HSA-3781865
Diseases associated with O-glycosylation of proteins R-HSA-3906995
Signaling by NOTCH R-HSA-157118
Diseases of metabolism R-HSA-5668914
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Pre-NOTCH Expression and Processing R-HSA-1912422
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
RNA Polymerase II Transcription R-HSA-73857
RUNX3 regulates NOTCH signaling R-HSA-8941856
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Formation of paraxial mesoderm R-HSA-9793380
Regulation of beta-cell development R-HSA-186712
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508
Transcriptional Regulation by MECP2 R-HSA-8986944
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Pre-NOTCH Processing in Golgi R-HSA-1912420
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stimuli R-HSA-8953897
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Generic Transcription Pathway R-HSA-212436
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744
Signaling by NOTCH1 R-HSA-1980143
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by NOTCH1 in Cancer R-HSA-2644603
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
Developmental Biology R-HSA-1266738
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Gene expression (Transcription) R-HSA-74160
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Regulation of NFE2L2 gene expression R-HSA-9818749
Signaling by NOTCH4 R-HSA-9013694
Defective LFNG causes SCDO3 R-HSA-5083630
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to chemical stress R-HSA-9711123
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826
Gastrulation R-HSA-9758941
Notch-HLH transcription pathway R-HSA-350054
Signaling by NOTCH3 R-HSA-9012852
Pre-NOTCH Transcription and Translation R-HSA-1912408
Cellular responses to stress R-HSA-2262752
Diseases of glycosylation R-HSA-3781865
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Nuclear events mediated by NFE2L2 R-HSA-9759194
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
Transcriptional regulation by RUNX3 R-HSA-8878159
Notch-HLH transcription pathway R-HSA-350054
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825
Cellular responses to stress R-HSA-2262752
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Transcriptional Regulation by MECP2 R-HSA-8986944
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulation of NFE2L2 gene expression R-HSA-9818749
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
Signal Transduction R-HSA-162582
Cellular response to chemical stress R-HSA-9711123
Diseases of metabolism R-HSA-5668914
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744
RUNX3 regulates NOTCH signaling R-HSA-8941856
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gastrulation R-HSA-9758941
Pre-NOTCH Processing in Golgi R-HSA-1912420
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Regulation of beta-cell development R-HSA-186712
Gene expression (Transcription) R-HSA-74160
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH3 R-HSA-9012852
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508
RNA Polymerase II Transcription R-HSA-73857
Defective LFNG causes SCDO3 R-HSA-5083630
Cellular responses to stimuli R-HSA-8953897
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Disease R-HSA-1643685
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399
Pre-NOTCH Expression and Processing R-HSA-1912422
Diseases associated with O-glycosylation of proteins R-HSA-3906995
Pre-NOTCH Transcription and Translation R-HSA-1912408
Generic Transcription Pathway R-HSA-212436
Formation of paraxial mesoderm R-HSA-9793380
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Diseases of metabolism R-HSA-5668914
Diseases associated with O-glycosylation of proteins R-HSA-3906995
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
Pre-NOTCH Expression and Processing R-HSA-1912422
Pre-NOTCH Transcription and Translation R-HSA-1912408
Notch-HLH transcription pathway R-HSA-350054
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX3 R-HSA-8878159
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH1 R-HSA-1980143
Regulation of beta-cell development R-HSA-186712
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744
Nuclear events mediated by NFE2L2 R-HSA-9759194
RNA Polymerase II Transcription R-HSA-73857
Formation of paraxial mesoderm R-HSA-9793380
Signaling by NOTCH R-HSA-157118
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Diseases of glycosylation R-HSA-3781865
Disease R-HSA-1643685
Transcriptional Regulation by MECP2 R-HSA-8986944
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH4 R-HSA-9013694
Regulation of NFE2L2 gene expression R-HSA-9818749
Gene expression (Transcription) R-HSA-74160
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective LFNG causes SCDO3 R-HSA-5083630
Pre-NOTCH Processing in Golgi R-HSA-1912420
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
Signaling by NOTCH3 R-HSA-9012852
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
RUNX3 regulates NOTCH signaling R-HSA-8941856
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Gastrulation R-HSA-9758941

Expression Atlas ENSG00000148400
LRG display in Ensembl gene LRG_1122
NCBI gene (formerly Entrezgene) 4851
GeneCards 7881
HGNC Symbol HGNC:7881
MIM gene 190198
MIM morbid 616028
UniProtKB Gene Name P46531
WikiGene 4851
Gene: SLC9A3
Ensembl ID : ENSG00000066230
Description: solute carrier family 9 member A3
Gene Synonyms: NHE-3,NHE3
2 APIs:
238 Possible Orthologues:

Sodium/Proton exchangers R-HSA-425986
Transport of small molecules R-HSA-382551
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
SLC-mediated transmembrane transport R-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
Sodium/Proton exchangers R-HSA-425986
SLC-mediated transmembrane transport R-HSA-425407
Transport of small molecules R-HSA-382551
Transport of small molecules R-HSA-382551
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
SLC-mediated transmembrane transport R-HSA-425407
Sodium/Proton exchangers R-HSA-425986
SLC-mediated transmembrane transport R-HSA-425407
Sodium/Proton exchangers R-HSA-425986
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
Transport of small molecules R-HSA-382551
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
SLC-mediated transmembrane transport R-HSA-425407
Transport of small molecules R-HSA-382551
Sodium/Proton exchangers R-HSA-425986
Transport of small molecules R-HSA-382551
SLC-mediated transmembrane transport R-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
Sodium/Proton exchangers R-HSA-425986
Transport of small molecules R-HSA-382551
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
SLC-mediated transmembrane transport R-HSA-425407
Sodium/Proton exchangers R-HSA-425986
SLC-mediated transmembrane transport R-HSA-425407
Transport of small molecules R-HSA-382551
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
Sodium/Proton exchangers R-HSA-425986
Transport of inorganic cations/anions and amino acids/oligopeptides R-HSA-425393
Transport of small molecules R-HSA-382551
SLC-mediated transmembrane transport R-HSA-425407
Sodium/Proton exchangers R-HSA-425986

Expression Atlas ENSG00000066230
NCBI gene (formerly Entrezgene) 6550
GeneCards 11073
HGNC Symbol HGNC:11073
MIM gene 182307
MIM morbid 616868
UniProtKB Gene Name P48764
WikiGene 6550