Gene: CSNK1E
Ensembl ID : ENSG00000213923
Description: casein kinase 1 epsilon
Gene Synonyms: CKIE,CKIEPSILON,HCKIE
1 APIs:
265 Possible Orthologues:

G2/M Transition R-HSA-69275
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Anchoring of the basal body to the plasma membrane R-HSA-5620912
rRNA processing in the nucleus and cytosol R-HSA-8868773
Mitotic Prometaphase R-HSA-68877
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
WNT mediated activation of DVL R-HSA-201688
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Mitotic G2-G2/M phases R-HSA-453274
Circadian Clock R-HSA-400253
Loss of Nlp from mitotic centrosomes R-HSA-380259
Cell Cycle, Mitotic R-HSA-69278
AURKA Activation by TPX2 R-HSA-8854518
Metabolism of RNA R-HSA-8953854
Cell Cycle R-HSA-1640170
Centrosome maturation R-HSA-380287
Organelle biogenesis and maintenance R-HSA-1852241
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
rRNA processing R-HSA-72312
Cilium Assembly R-HSA-5617833
Centrosome maturation R-HSA-380287
rRNA processing in the nucleus and cytosol R-HSA-8868773
Circadian Clock R-HSA-400253
Signal Transduction R-HSA-162582
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Organelle biogenesis and maintenance R-HSA-1852241
TCF dependent signaling in response to WNT R-HSA-201681
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Cell Cycle R-HSA-1640170
Mitotic Prometaphase R-HSA-68877
rRNA processing R-HSA-72312
G2/M Transition R-HSA-69275
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Mitotic G2-G2/M phases R-HSA-453274
AURKA Activation by TPX2 R-HSA-8854518
Signaling by WNT R-HSA-195721
Metabolism of RNA R-HSA-8953854
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
M Phase R-HSA-68886
Loss of Nlp from mitotic centrosomes R-HSA-380259
Cell Cycle, Mitotic R-HSA-69278
Cilium Assembly R-HSA-5617833
WNT mediated activation of DVL R-HSA-201688
Cilium Assembly R-HSA-5617833
M Phase R-HSA-68886
rRNA processing in the nucleus and cytosol R-HSA-8868773
Circadian Clock R-HSA-400253
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Loss of Nlp from mitotic centrosomes R-HSA-380259
Organelle biogenesis and maintenance R-HSA-1852241
Centrosome maturation R-HSA-380287
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
G2/M Transition R-HSA-69275
WNT mediated activation of DVL R-HSA-201688
Mitotic Prometaphase R-HSA-68877
Signaling by WNT R-HSA-195721
rRNA processing R-HSA-72312
AURKA Activation by TPX2 R-HSA-8854518
Signal Transduction R-HSA-162582
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Metabolism of RNA R-HSA-8953854
Cell Cycle R-HSA-1640170
Anchoring of the basal body to the plasma membrane R-HSA-5620912
rRNA processing in the nucleus and cytosol R-HSA-8868773
Mitotic Prometaphase R-HSA-68877
Organelle biogenesis and maintenance R-HSA-1852241
G2/M Transition R-HSA-69275
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Cell Cycle R-HSA-1640170
WNT mediated activation of DVL R-HSA-201688
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
rRNA processing R-HSA-72312
Centrosome maturation R-HSA-380287
Signal Transduction R-HSA-162582
Mitotic G2-G2/M phases R-HSA-453274
AURKA Activation by TPX2 R-HSA-8854518
Metabolism of RNA R-HSA-8953854
M Phase R-HSA-68886
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Signaling by WNT R-HSA-195721
Circadian Clock R-HSA-400253
Cell Cycle, Mitotic R-HSA-69278
Loss of Nlp from mitotic centrosomes R-HSA-380259
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Cilium Assembly R-HSA-5617833
AURKA Activation by TPX2 R-HSA-8854518
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Signal Transduction R-HSA-162582
M Phase R-HSA-68886
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
rRNA processing R-HSA-72312
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Mitotic Prometaphase R-HSA-68877
WNT mediated activation of DVL R-HSA-201688
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Metabolism of RNA R-HSA-8953854
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Signaling by WNT R-HSA-195721
rRNA processing in the nucleus and cytosol R-HSA-8868773
Centrosome maturation R-HSA-380287
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Loss of Nlp from mitotic centrosomes R-HSA-380259
G2/M Transition R-HSA-69275
Cell Cycle R-HSA-1640170
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Circadian Clock R-HSA-400253
Organelle biogenesis and maintenance R-HSA-1852241
TCF dependent signaling in response to WNT R-HSA-201681
Cilium Assembly R-HSA-5617833
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
rRNA processing in the nucleus and cytosol R-HSA-8868773
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Signal Transduction R-HSA-162582
Organelle biogenesis and maintenance R-HSA-1852241
Anchoring of the basal body to the plasma membrane R-HSA-5620912
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by WNT R-HSA-195721
Mitotic Prometaphase R-HSA-68877
Circadian Clock R-HSA-400253
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Cell Cycle, Mitotic R-HSA-69278
Loss of Nlp from mitotic centrosomes R-HSA-380259
Cilium Assembly R-HSA-5617833
rRNA processing R-HSA-72312
Metabolism of RNA R-HSA-8953854
Mitotic G2-G2/M phases R-HSA-453274
AURKA Activation by TPX2 R-HSA-8854518
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
G2/M Transition R-HSA-69275
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Cell Cycle R-HSA-1640170
Centrosome maturation R-HSA-380287
M Phase R-HSA-68886
WNT mediated activation of DVL R-HSA-201688
Mitotic G2-G2/M phases R-HSA-453274
Signaling by WNT R-HSA-195721
TCF dependent signaling in response to WNT R-HSA-201681
Signal Transduction R-HSA-162582
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
G2/M Transition R-HSA-69275
rRNA processing in the nucleus and cytosol R-HSA-8868773
Mitotic Prometaphase R-HSA-68877
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
WNT mediated activation of DVL R-HSA-201688
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Loss of Nlp from mitotic centrosomes R-HSA-380259
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
rRNA processing R-HSA-72312
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Centrosome maturation R-HSA-380287
Cilium Assembly R-HSA-5617833
Circadian Clock R-HSA-400253
AURKA Activation by TPX2 R-HSA-8854518
M Phase R-HSA-68886
Metabolism of RNA R-HSA-8953854
Organelle biogenesis and maintenance R-HSA-1852241
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Cell Cycle R-HSA-1640170
Signaling by WNT R-HSA-195721
Cilium Assembly R-HSA-5617833
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Centrosome maturation R-HSA-380287
G2/M Transition R-HSA-69275
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Circadian Clock R-HSA-400253
Signal Transduction R-HSA-162582
AURKA Activation by TPX2 R-HSA-8854518
WNT mediated activation of DVL R-HSA-201688
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
rRNA processing R-HSA-72312
Mitotic G2-G2/M phases R-HSA-453274
Metabolism of RNA R-HSA-8953854
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Mitotic Prometaphase R-HSA-68877
M Phase R-HSA-68886
Cell Cycle, Mitotic R-HSA-69278
TCF dependent signaling in response to WNT R-HSA-201681
Organelle biogenesis and maintenance R-HSA-1852241
Loss of Nlp from mitotic centrosomes R-HSA-380259
rRNA processing in the nucleus and cytosol R-HSA-8868773
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
rRNA processing R-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Metabolism of RNA R-HSA-8953854
WNT mediated activation of DVL R-HSA-201688
AURKA Activation by TPX2 R-HSA-8854518
Mitotic Prometaphase R-HSA-68877
M Phase R-HSA-68886
Cell Cycle, Mitotic R-HSA-69278
Loss of Nlp from mitotic centrosomes R-HSA-380259
Mitotic G2-G2/M phases R-HSA-453274
G2/M Transition R-HSA-69275
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Circadian Clock R-HSA-400253
Signaling by WNT R-HSA-195721
Anchoring of the basal body to the plasma membrane R-HSA-5620912
rRNA processing in the nucleus and cytosol R-HSA-8868773
TCF dependent signaling in response to WNT R-HSA-201681
Cilium Assembly R-HSA-5617833
Signal Transduction R-HSA-162582
Organelle biogenesis and maintenance R-HSA-1852241
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Centrosome maturation R-HSA-380287
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Cell Cycle R-HSA-1640170
Organelle biogenesis and maintenance R-HSA-1852241
Circadian Clock R-HSA-400253
Signal Transduction R-HSA-162582
rRNA processing R-HSA-72312
Centrosome maturation R-HSA-380287
G2/M Transition R-HSA-69275
Signaling by WNT R-HSA-195721
M Phase R-HSA-68886
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
TCF dependent signaling in response to WNT R-HSA-201681
WNT mediated activation of DVL R-HSA-201688
Metabolism of RNA R-HSA-8953854
Loss of Nlp from mitotic centrosomes R-HSA-380259
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
AURKA Activation by TPX2 R-HSA-8854518
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Cilium Assembly R-HSA-5617833
Cell Cycle R-HSA-1640170
rRNA processing in the nucleus and cytosol R-HSA-8868773
rRNA processing in the nucleus and cytosol R-HSA-8868773
Metabolism of RNA R-HSA-8953854
Cilium Assembly R-HSA-5617833
AURKA Activation by TPX2 R-HSA-8854518
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Loss of Nlp from mitotic centrosomes R-HSA-380259
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
M Phase R-HSA-68886
WNT mediated activation of DVL R-HSA-201688
Mitotic Prometaphase R-HSA-68877
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Mitotic G2-G2/M phases R-HSA-453274
Signaling by WNT R-HSA-195721
Centrosome maturation R-HSA-380287
Signal Transduction R-HSA-162582
rRNA processing R-HSA-72312
TCF dependent signaling in response to WNT R-HSA-201681
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Organelle biogenesis and maintenance R-HSA-1852241
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Circadian Clock R-HSA-400253
Cell Cycle R-HSA-1640170

Expression Atlas ENSG00000213923
NCBI gene (formerly Entrezgene) 1454
GeneCards 2453
HGNC Symbol HGNC:2453
MIM gene 600863
UniProtKB Gene Name Q5U045
WikiGene 1454
Gene: CDK2
Ensembl ID : ENSG00000123374
Description: cyclin dependent kinase 2
Gene Synonyms:
11 APIs:
203 Possible Orthologues:

G2/M Transition R-HSA-69275
G2 Phase R-HSA-68911
Regulation of mitotic cell cycle R-HSA-453276
PTK6 Regulates Cell Cycle R-HSA-8849470
RNA Polymerase II Transcription R-HSA-73857
S Phase R-HSA-69242
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stimuli R-HSA-8953897
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Generic Transcription Pathway R-HSA-212436
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Synthesis of DNA R-HSA-69239
DNA Replication R-HSA-69306
Activation of the pre-replicative complex R-HSA-68962
Chromosome Maintenance R-HSA-73886
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Double-Strand Break Repair R-HSA-5693532
DNA Replication Pre-Initiation R-HSA-69002
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
DNA Repair R-HSA-73894
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular responses to stress R-HSA-2262752
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of TP53 Degradation R-HSA-6804757
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Switching of origins to a post-replicative state R-HSA-69052
Factors involved in megakaryocyte development and platelet production R-HSA-983231
G2/M Transition R-HSA-69275
G0 and Early G1 R-HSA-1538133
Diseases of mitotic cell cycle R-HSA-9675126
Cyclin D associated events in G1 R-HSA-69231
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
Developmental Biology R-HSA-1266738
Transcriptional regulation of granulopoiesis R-HSA-9616222
G1/S Transition R-HSA-69206
Meiosis R-HSA-1500620
Mitotic G2-G2/M phases R-HSA-453274
Regulation of TP53 Activity R-HSA-5633007
Telomere Maintenance R-HSA-157579
Meiotic recombination R-HSA-912446
Cellular Senescence R-HSA-2559583
Cell Cycle Checkpoints R-HSA-69620
Telomere Extension By Telomerase R-HSA-171319
Orc1 removal from chromatin R-HSA-68949
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Disease R-HSA-1643685
G2 Phase R-HSA-68911
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by PTK6 R-HSA-8848021
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Processing of DNA double-strand break ends R-HSA-5693607
Regulation of TP53 Expression and Degradation R-HSA-6806003
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Reproduction R-HSA-1474165
G1 Phase R-HSA-69236
G2/M Checkpoints R-HSA-69481
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Cell Cycle R-HSA-1640170
Homology Directed Repair R-HSA-5693538
Cell Cycle, Mitotic R-HSA-69278
Activation of ATR in response to replication stress R-HSA-176187
Gene expression (Transcription) R-HSA-74160
Extension of Telomeres R-HSA-180786
Telomere Maintenance R-HSA-157579
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Reproduction R-HSA-1474165
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
Regulation of TP53 Expression and Degradation R-HSA-6806003
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by PTK6 R-HSA-8848021
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Degradation R-HSA-6804757
Cyclin D associated events in G1 R-HSA-69231
G0 and Early G1 R-HSA-1538133
Factors involved in megakaryocyte development and platelet production R-HSA-983231
G1/S DNA Damage Checkpoints R-HSA-69615
Extension of Telomeres R-HSA-180786
Synthesis of DNA R-HSA-69239
DNA Repair R-HSA-73894
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
DNA Replication R-HSA-69306
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
p53-Dependent G1 DNA Damage Response R-HSA-69563
Developmental Biology R-HSA-1266738
Diseases of mitotic cell cycle R-HSA-9675126
Disease R-HSA-1643685
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G2-G2/M phases R-HSA-453274
G2/M Checkpoints R-HSA-69481
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Meiotic recombination R-HSA-912446
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Regulation of TP53 Activity R-HSA-5633007
Transcriptional regulation of granulopoiesis R-HSA-9616222
PTK6 Regulates Cell Cycle R-HSA-8849470
Cyclin E associated events during G1/S transition R-HSA-69202
Processing of DNA double-strand break ends R-HSA-5693607
Orc1 removal from chromatin R-HSA-68949
Switching of origins to a post-replicative state R-HSA-69052
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Meiosis R-HSA-1500620
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Homology Directed Repair R-HSA-5693538
Activation of the pre-replicative complex R-HSA-68962
G2 Phase R-HSA-68911
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
RNA Polymerase II Transcription R-HSA-73857
Telomere Extension By Telomerase R-HSA-171319
DNA Double-Strand Break Repair R-HSA-5693532
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
S Phase R-HSA-69242
Cell Cycle, Mitotic R-HSA-69278
Activation of ATR in response to replication stress R-HSA-176187
Cellular Senescence R-HSA-2559583
Chromosome Maintenance R-HSA-73886
G1/S Transition R-HSA-69206
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
DNA Replication Pre-Initiation R-HSA-69002
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hemostasis R-HSA-109582
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
G1 Phase R-HSA-69236
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
Cell Cycle Checkpoints R-HSA-69620
G0 and Early G1 R-HSA-1538133
Meiotic recombination R-HSA-912446
G2/M Checkpoints R-HSA-69481
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Developmental Biology R-HSA-1266738
Hemostasis R-HSA-109582
Generic Transcription Pathway R-HSA-212436
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
Mitotic G2-G2/M phases R-HSA-453274
PTK6 Regulates Cell Cycle R-HSA-8849470
G1 Phase R-HSA-69236
Signal Transduction R-HSA-162582
Orc1 removal from chromatin R-HSA-68949
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Regulation of mitotic cell cycle R-HSA-453276
S Phase R-HSA-69242
Telomere Extension By Telomerase R-HSA-171319
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Signaling by PTK6 R-HSA-8848021
DNA Replication R-HSA-69306
G1/S Transition R-HSA-69206
Mitotic G1 phase and G1/S transition R-HSA-453279
Activation of ATR in response to replication stress R-HSA-176187
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cell Cycle Checkpoints R-HSA-69620
Processing of DNA double-strand break ends R-HSA-5693607
Gene expression (Transcription) R-HSA-74160
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional Regulation by TP53 R-HSA-3700989
Meiosis R-HSA-1500620
Disease R-HSA-1643685
Switching of origins to a post-replicative state R-HSA-69052
Cyclin D associated events in G1 R-HSA-69231
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G2/M Transition R-HSA-69275
Activation of the pre-replicative complex R-HSA-68962
Regulation of TP53 Degradation R-HSA-6804757
DNA Repair R-HSA-73894
RNA Polymerase II Transcription R-HSA-73857
Telomere Maintenance R-HSA-157579
Diseases of mitotic cell cycle R-HSA-9675126
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stimuli R-HSA-8953897
Chromosome Maintenance R-HSA-73886
Extension of Telomeres R-HSA-180786
Homology Directed Repair R-HSA-5693538
Cell Cycle, Mitotic R-HSA-69278
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
DNA Double-Strand Break Repair R-HSA-5693532
Reproduction R-HSA-1474165
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Regulation of TP53 Activity R-HSA-5633007
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Transcriptional regulation of granulopoiesis R-HSA-9616222
Cell Cycle R-HSA-1640170
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Cellular responses to stress R-HSA-2262752
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Synthesis of DNA R-HSA-69239
Regulation of TP53 Expression and Degradation R-HSA-6806003
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
Diseases of mitotic cell cycle R-HSA-9675126
DNA Double-Strand Break Repair R-HSA-5693532
Cellular responses to stimuli R-HSA-8953897
Reproduction R-HSA-1474165
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signal Transduction R-HSA-162582
Cyclin D associated events in G1 R-HSA-69231
Transcriptional regulation of granulopoiesis R-HSA-9616222
DNA Repair R-HSA-73894
Gene expression (Transcription) R-HSA-74160
G2/M Checkpoints R-HSA-69481
Cell Cycle, Mitotic R-HSA-69278
Extension of Telomeres R-HSA-180786
G0 and Early G1 R-HSA-1538133
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
G1/S Transition R-HSA-69206
G2 Phase R-HSA-68911
Cell Cycle R-HSA-1640170
Meiotic recombination R-HSA-912446
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Mitotic G1 phase and G1/S transition R-HSA-453279
G1 Phase R-HSA-69236
Developmental Biology R-HSA-1266738
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
G1/S DNA Damage Checkpoints R-HSA-69615
Processing of DNA double-strand break ends R-HSA-5693607
Telomere Maintenance R-HSA-157579
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Chromosome Maintenance R-HSA-73886
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signaling by PTK6 R-HSA-8848021
Cellular Senescence R-HSA-2559583
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
Regulation of TP53 Degradation R-HSA-6804757
Cyclin E associated events during G1/S transition R-HSA-69202
Hemostasis R-HSA-109582
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Meiosis R-HSA-1500620
Telomere Extension By Telomerase R-HSA-171319
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Activation of ATR in response to replication stress R-HSA-176187
Orc1 removal from chromatin R-HSA-68949
Activation of the pre-replicative complex R-HSA-68962
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
PTK6 Regulates Cell Cycle R-HSA-8849470
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
S Phase R-HSA-69242
DNA Replication Pre-Initiation R-HSA-69002
Disease R-HSA-1643685
Regulation of mitotic cell cycle R-HSA-453276
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity R-HSA-5633007
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G2/M Transition R-HSA-69275
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Switching of origins to a post-replicative state R-HSA-69052
RNA Polymerase II Transcription R-HSA-73857
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Homology Directed Repair R-HSA-5693538
Cellular responses to stress R-HSA-2262752
Activation of the pre-replicative complex R-HSA-68962
Cyclin D associated events in G1 R-HSA-69231
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic G1 phase and G1/S transition R-HSA-453279
G2 Phase R-HSA-68911
DNA Repair R-HSA-73894
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular Senescence R-HSA-2559583
Meiotic recombination R-HSA-912446
Processing of DNA double-strand break ends R-HSA-5693607
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Extension of Telomeres R-HSA-180786
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
S Phase R-HSA-69242
Meiosis R-HSA-1500620
DNA Double-Strand Break Repair R-HSA-5693532
Transcriptional Regulation by TP53 R-HSA-3700989
G1/S DNA Damage Checkpoints R-HSA-69615
Telomere Extension By Telomerase R-HSA-171319
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Switching of origins to a post-replicative state R-HSA-69052
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cell Cycle, Mitotic R-HSA-69278
Synthesis of DNA R-HSA-69239
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
Orc1 removal from chromatin R-HSA-68949
Cellular responses to stress R-HSA-2262752
Reproduction R-HSA-1474165
Cell Cycle Checkpoints R-HSA-69620
Signaling by PTK6 R-HSA-8848021
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Activation of ATR in response to replication stress R-HSA-176187
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Replication R-HSA-69306
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Telomere Maintenance R-HSA-157579
Chromosome Maintenance R-HSA-73886
G1 Phase R-HSA-69236
Regulation of TP53 Degradation R-HSA-6804757
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Disease R-HSA-1643685
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
G2/M Transition R-HSA-69275
PTK6 Regulates Cell Cycle R-HSA-8849470
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Hemostasis R-HSA-109582
G2/M Checkpoints R-HSA-69481
Mitotic G2-G2/M phases R-HSA-453274
Cellular responses to stimuli R-HSA-8953897
Homology Directed Repair R-HSA-5693538
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Regulation of mitotic cell cycle R-HSA-453276
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Diseases of mitotic cell cycle R-HSA-9675126
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of TP53 Activity R-HSA-5633007
Transcriptional regulation of granulopoiesis R-HSA-9616222
Cyclin E associated events during G1/S transition R-HSA-69202
G0 and Early G1 R-HSA-1538133
Signal Transduction R-HSA-162582
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Orc1 removal from chromatin R-HSA-68949
Cyclin E associated events during G1/S transition R-HSA-69202
Meiosis R-HSA-1500620
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Cell Cycle R-HSA-1640170
Telomere Maintenance R-HSA-157579
Reproduction R-HSA-1474165
DNA Double-Strand Break Repair R-HSA-5693532
G2/M Transition R-HSA-69275
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Disease R-HSA-1643685
G1 Phase R-HSA-69236
S Phase R-HSA-69242
Developmental Biology R-HSA-1266738
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Diseases of mitotic cell cycle R-HSA-9675126
Cell Cycle Checkpoints R-HSA-69620
Mitotic G1 phase and G1/S transition R-HSA-453279
PTK6 Regulates Cell Cycle R-HSA-8849470
Hemostasis R-HSA-109582
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Transcriptional Regulation by TP53 R-HSA-3700989
Cellular responses to stimuli R-HSA-8953897
Telomere Extension By Telomerase R-HSA-171319
G2/M Checkpoints R-HSA-69481
Synthesis of DNA R-HSA-69239
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
DNA Replication R-HSA-69306
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Chromosome Maintenance R-HSA-73886
DNA Replication Pre-Initiation R-HSA-69002
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation of granulopoiesis R-HSA-9616222
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
Extension of Telomeres R-HSA-180786
Processing of DNA double-strand break ends R-HSA-5693607
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Homology Directed Repair R-HSA-5693538
Signal Transduction R-HSA-162582
G0 and Early G1 R-HSA-1538133
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Regulation of mitotic cell cycle R-HSA-453276
Regulation of TP53 Degradation R-HSA-6804757
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Meiotic recombination R-HSA-912446
DNA Repair R-HSA-73894
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Cyclin D associated events in G1 R-HSA-69231
Mitotic G2-G2/M phases R-HSA-453274
Generic Transcription Pathway R-HSA-212436
Cell Cycle, Mitotic R-HSA-69278
G1/S Transition R-HSA-69206
G2 Phase R-HSA-68911
Activation of ATR in response to replication stress R-HSA-176187
Signaling by PTK6 R-HSA-8848021
Regulation of TP53 Activity R-HSA-5633007
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Cellular responses to stress R-HSA-2262752
Activation of the pre-replicative complex R-HSA-68962
Regulation of TP53 Expression and Degradation R-HSA-6806003
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of mitotic cell cycle R-HSA-9675126
Activation of ATR in response to replication stress R-HSA-176187
Chromosome Maintenance R-HSA-73886
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Cellular Senescence R-HSA-2559583
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle Checkpoints R-HSA-69620
DNA Repair R-HSA-73894
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G0 and Early G1 R-HSA-1538133
PTK6 Regulates Cell Cycle R-HSA-8849470
Orc1 removal from chromatin R-HSA-68949
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stress R-HSA-2262752
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Disease R-HSA-1643685
Regulation of TP53 Degradation R-HSA-6804757
S Phase R-HSA-69242
Generic Transcription Pathway R-HSA-212436
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
G1/S Transition R-HSA-69206
Processing of DNA double-strand break ends R-HSA-5693607
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cyclin D associated events in G1 R-HSA-69231
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
DNA Replication R-HSA-69306
Synthesis of DNA R-HSA-69239
Regulation of TP53 Activity R-HSA-5633007
G1 Phase R-HSA-69236
Telomere Maintenance R-HSA-157579
DNA Double-Strand Break Repair R-HSA-5693532
Regulation of mitotic cell cycle R-HSA-453276
Meiosis R-HSA-1500620
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Meiotic recombination R-HSA-912446
Activation of the pre-replicative complex R-HSA-68962
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Cell Cycle R-HSA-1640170
Hemostasis R-HSA-109582
DNA Replication Pre-Initiation R-HSA-69002
G2 Phase R-HSA-68911
G2/M Transition R-HSA-69275
Transcriptional regulation of granulopoiesis R-HSA-9616222
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
p53-Dependent G1 DNA Damage Response R-HSA-69563
Reproduction R-HSA-1474165
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of TP53 Expression and Degradation R-HSA-6806003
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Transcriptional Regulation by TP53 R-HSA-3700989
Telomere Extension By Telomerase R-HSA-171319
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Switching of origins to a post-replicative state R-HSA-69052
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Mitotic G1 phase and G1/S transition R-HSA-453279
Homology Directed Repair R-HSA-5693538
G2/M Checkpoints R-HSA-69481
Extension of Telomeres R-HSA-180786
Cellular responses to stimuli R-HSA-8953897
Signaling by PTK6 R-HSA-8848021
PTK6 Regulates Cell Cycle R-HSA-8849470
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Dependent G1 DNA Damage Response R-HSA-69563
Extension of Telomeres R-HSA-180786
Cyclin D associated events in G1 R-HSA-69231
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Orc1 removal from chromatin R-HSA-68949
Cellular responses to stimuli R-HSA-8953897
Regulation of mitotic cell cycle R-HSA-453276
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by TP53 R-HSA-3700989
Cell Cycle, Mitotic R-HSA-69278
G0 and Early G1 R-HSA-1538133
Mitotic G2-G2/M phases R-HSA-453274
Activation of ATR in response to replication stress R-HSA-176187
Homology Directed Repair R-HSA-5693538
Meiosis R-HSA-1500620
Synthesis of DNA R-HSA-69239
Cyclin E associated events during G1/S transition R-HSA-69202
G1 Phase R-HSA-69236
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of TP53 Expression and Degradation R-HSA-6806003
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Transcriptional regulation of granulopoiesis R-HSA-9616222
Regulation of TP53 Degradation R-HSA-6804757
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
DNA Replication R-HSA-69306
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
Switching of origins to a post-replicative state R-HSA-69052
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hemostasis R-HSA-109582
Cell Cycle R-HSA-1640170
G2/M Transition R-HSA-69275
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
DNA Double-Strand Break Repair R-HSA-5693532
Chromosome Maintenance R-HSA-73886
Signal Transduction R-HSA-162582
Diseases of mitotic cell cycle R-HSA-9675126
Reproduction R-HSA-1474165
Signaling by PTK6 R-HSA-8848021
Telomere Maintenance R-HSA-157579
S Phase R-HSA-69242
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
DNA Repair R-HSA-73894
G2 Phase R-HSA-68911
Cellular Senescence R-HSA-2559583
G1/S Transition R-HSA-69206
Telomere Extension By Telomerase R-HSA-171319
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Meiotic recombination R-HSA-912446
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stress R-HSA-2262752
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
RNA Polymerase II Transcription R-HSA-73857
Processing of DNA double-strand break ends R-HSA-5693607
G1/S DNA Damage Checkpoints R-HSA-69615
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Activation of the pre-replicative complex R-HSA-68962
G2/M Checkpoints R-HSA-69481
Regulation of TP53 Activity R-HSA-5633007
DNA Replication Pre-Initiation R-HSA-69002
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
Mitotic G1 phase and G1/S transition R-HSA-453279
Hemostasis R-HSA-109582
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
G2/M Checkpoints R-HSA-69481
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
S Phase R-HSA-69242
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle Checkpoints R-HSA-69620
Diseases of mitotic cell cycle R-HSA-9675126
Cell Cycle, Mitotic R-HSA-69278
Reproduction R-HSA-1474165
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Synthesis of DNA R-HSA-69239
DNA Replication R-HSA-69306
Gene expression (Transcription) R-HSA-74160
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of ATR in response to replication stress R-HSA-176187
Cyclin E associated events during G1/S transition R-HSA-69202
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Regulation of TP53 Expression and Degradation R-HSA-6806003
Regulation of TP53 Degradation R-HSA-6804757
G0 and Early G1 R-HSA-1538133
Transcriptional regulation of granulopoiesis R-HSA-9616222
DNA Repair R-HSA-73894
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
G1 Phase R-HSA-69236
Regulation of TP53 Activity R-HSA-5633007
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Chromosome Maintenance R-HSA-73886
Orc1 removal from chromatin R-HSA-68949
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Extension of Telomeres R-HSA-180786
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Regulation of mitotic cell cycle R-HSA-453276
Activation of the pre-replicative complex R-HSA-68962
Transcriptional Regulation by TP53 R-HSA-3700989
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
Cell Cycle R-HSA-1640170
Signaling by PTK6 R-HSA-8848021
Developmental Biology R-HSA-1266738
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cellular Senescence R-HSA-2559583
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Switching of origins to a post-replicative state R-HSA-69052
Disease R-HSA-1643685
p53-Dependent G1 DNA Damage Response R-HSA-69563
Mitotic G2-G2/M phases R-HSA-453274
Meiosis R-HSA-1500620
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
DNA Double-Strand Break Repair R-HSA-5693532
Telomere Maintenance R-HSA-157579
Cyclin D associated events in G1 R-HSA-69231
Homology Directed Repair R-HSA-5693538
G2 Phase R-HSA-68911
G1/S Transition R-HSA-69206
PTK6 Regulates Cell Cycle R-HSA-8849470
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signal Transduction R-HSA-162582
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
DNA Replication Pre-Initiation R-HSA-69002
Generic Transcription Pathway R-HSA-212436
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular responses to stress R-HSA-2262752
Telomere Extension By Telomerase R-HSA-171319
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular responses to stimuli R-HSA-8953897
Meiotic recombination R-HSA-912446
Processing of DNA double-strand break ends R-HSA-5693607
G1/S DNA Damage Checkpoints R-HSA-69615
G1 Phase R-HSA-69236
Cellular responses to stress R-HSA-2262752
G2/M Transition R-HSA-69275
Orc1 removal from chromatin R-HSA-68949
Diseases of mitotic cell cycle R-HSA-9675126
Regulation of TP53 Degradation R-HSA-6804757
Cyclin D associated events in G1 R-HSA-69231
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PTK6 Regulates Cell Cycle R-HSA-8849470
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Regulation of mitotic cell cycle R-HSA-453276
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Reproduction R-HSA-1474165
Extension of Telomeres R-HSA-180786
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular Senescence R-HSA-2559583
Switching of origins to a post-replicative state R-HSA-69052
Hemostasis R-HSA-109582
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cell Cycle Checkpoints R-HSA-69620
Activation of the pre-replicative complex R-HSA-68962
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signal Transduction R-HSA-162582
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S DNA Damage Checkpoints R-HSA-69615
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
DNA Repair R-HSA-73894
Regulation of TP53 Expression and Degradation R-HSA-6806003
G0 and Early G1 R-HSA-1538133
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
DNA Double-Strand Break Repair R-HSA-5693532
Meiosis R-HSA-1500620
G2 Phase R-HSA-68911
Homology Directed Repair R-HSA-5693538
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cell Cycle R-HSA-1640170
Meiotic recombination R-HSA-912446
Telomere Extension By Telomerase R-HSA-171319
RNA Polymerase II Transcription R-HSA-73857
Cyclin E associated events during G1/S transition R-HSA-69202
G1/S Transition R-HSA-69206
Activation of ATR in response to replication stress R-HSA-176187
DNA Replication R-HSA-69306
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Mitotic G2-G2/M phases R-HSA-453274
Telomere Maintenance R-HSA-157579
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Developmental Biology R-HSA-1266738
Signaling by PTK6 R-HSA-8848021
Generic Transcription Pathway R-HSA-212436
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Disease R-HSA-1643685
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Synthesis of DNA R-HSA-69239
Chromosome Maintenance R-HSA-73886
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
G2/M Checkpoints R-HSA-69481
Transcriptional Regulation by TP53 R-HSA-3700989
Cellular responses to stimuli R-HSA-8953897
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity R-HSA-5633007
DNA Replication Pre-Initiation R-HSA-69002
S Phase R-HSA-69242
Transcriptional regulation of granulopoiesis R-HSA-9616222
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Processing of DNA double-strand break ends R-HSA-5693607
Cell Cycle, Mitotic R-HSA-69278

Expression Atlas ENSG00000123374
NCBI gene (formerly Entrezgene) 1017
GeneCards 1771
HGNC Symbol HGNC:1771
MIM gene 116953
UniProtKB Gene Name P24941
WikiGene 1017
Gene: CDK1
Ensembl ID : ENSG00000170312
Description: cyclin dependent kinase 1
Gene Synonyms: CDC2,CDC28A
9 APIs:
241 Possible Orthologues:

Mitotic Prophase R-HSA-68875
Gene expression (Transcription) R-HSA-74160
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
Mitotic G1 phase and G1/S transition R-HSA-453279
Deubiquitination R-HSA-5688426
G2/M Checkpoints R-HSA-69481
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Regulation of TP53 Degradation R-HSA-6804757
RNA Polymerase II Transcription R-HSA-73857
MAPK6/MAPK4 signaling R-HSA-5687128
Condensation of Prometaphase Chromosomes R-HSA-2514853
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Resolution of Sister Chromatid Cohesion R-HSA-2500257
E2F mediated regulation of DNA replication R-HSA-113510
Mitotic Prophase R-HSA-68875
Transcriptional Regulation by TP53 R-HSA-3700989
Ovarian tumor domain proteases R-HSA-5689896
G2/M Transition R-HSA-69275
Nuclear Envelope Breakdown R-HSA-2980766
G1/S-Specific Transcription R-HSA-69205
Phosphorylation of Emi1 R-HSA-176417
G2/M DNA replication checkpoint R-HSA-69478
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Anchoring of the basal body to the plasma membrane R-HSA-5620912
M Phase R-HSA-68886
Phosphorylation of the APC/C R-HSA-176412
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Cell Cycle, Mitotic R-HSA-69278
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Mitotic Prometaphase R-HSA-68877
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Gene expression (Transcription) R-HSA-74160
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
G1/S Transition R-HSA-69206
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Cilium Assembly R-HSA-5617833
Mitotic Anaphase R-HSA-68882
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
MAPK family signaling cascades R-HSA-5683057
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
MAPK3 (ERK1) activation R-HSA-110056
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle Checkpoints R-HSA-69620
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G2/M DNA damage checkpoint R-HSA-69473
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
MASTL Facilitates Mitotic Progression R-HSA-2465910
Centrosome maturation R-HSA-380287
Regulation of TP53 Activity R-HSA-5633007
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Condensation of Prophase Chromosomes R-HSA-2299718
RAF-independent MAPK1/3 activation R-HSA-112409
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Cell Cycle R-HSA-1640170
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
AURKA Activation by TPX2 R-HSA-8854518
Loss of Nlp from mitotic centrosomes R-HSA-380259
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G0 and Early G1 R-HSA-1538133
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic Metaphase and Anaphase R-HSA-2555396
Organelle biogenesis and maintenance R-HSA-1852241
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Regulation of mitotic cell cycle R-HSA-453276
MAPK3 (ERK1) activation R-HSA-110056
AURKA Activation by TPX2 R-HSA-8854518
G1/S Transition R-HSA-69206
Mitotic Anaphase R-HSA-68882
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Expression and Degradation R-HSA-6806003
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Loss of Nlp from mitotic centrosomes R-HSA-380259
Phosphorylation of Emi1 R-HSA-176417
Nuclear Envelope Breakdown R-HSA-2980766
G0 and Early G1 R-HSA-1538133
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
Mitotic Metaphase and Anaphase R-HSA-2555396
Ovarian tumor domain proteases R-HSA-5689896
Depolymerisation of the Nuclear Lamina R-HSA-4419969
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Mitotic G1 phase and G1/S transition R-HSA-453279
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
G2/M DNA replication checkpoint R-HSA-69478
Organelle biogenesis and maintenance R-HSA-1852241
Mitotic G2-G2/M phases R-HSA-453274
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
E2F mediated regulation of DNA replication R-HSA-113510
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
G2/M DNA damage checkpoint R-HSA-69473
MAPK1/MAPK3 signaling R-HSA-5684996
Generic Transcription Pathway R-HSA-212436
Mitotic Prophase R-HSA-68875
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Gene expression (Transcription) R-HSA-74160
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Phosphorylation of the APC/C R-HSA-176412
Regulation of TP53 Degradation R-HSA-6804757
Cilium Assembly R-HSA-5617833
Centrosome maturation R-HSA-380287
Deubiquitination R-HSA-5688426
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G2/M Checkpoints R-HSA-69481
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
M Phase R-HSA-68886
Transcriptional Regulation by TP53 R-HSA-3700989
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Cell Cycle R-HSA-1640170
Condensation of Prometaphase Chromosomes R-HSA-2514853
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Transcriptional regulation by RUNX2 R-HSA-8878166
MASTL Facilitates Mitotic Progression R-HSA-2465910
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Regulation of TP53 Activity R-HSA-5633007
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Cell Cycle Checkpoints R-HSA-69620
Metabolism of proteins R-HSA-392499
MAPK family signaling cascades R-HSA-5683057
Condensation of Prophase Chromosomes R-HSA-2299718
G1/S-Specific Transcription R-HSA-69205
RAF-independent MAPK1/3 activation R-HSA-112409
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mitotic cell cycle R-HSA-453276
Post-translational protein modification R-HSA-597592
Ovarian tumor domain proteases R-HSA-5689896
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nuclear Envelope Breakdown R-HSA-2980766
Condensation of Prometaphase Chromosomes R-HSA-2514853
Loss of Nlp from mitotic centrosomes R-HSA-380259
Deubiquitination R-HSA-5688426
AURKA Activation by TPX2 R-HSA-8854518
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Depolymerisation of the Nuclear Lamina R-HSA-4419969
RAF-independent MAPK1/3 activation R-HSA-112409
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of proteins R-HSA-392499
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Regulation of TP53 Expression and Degradation R-HSA-6806003
Mitotic Prometaphase R-HSA-68877
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
M Phase R-HSA-68886
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic Anaphase R-HSA-68882
G2/M Checkpoints R-HSA-69481
G0 and Early G1 R-HSA-1538133
G1/S Transition R-HSA-69206
Mitotic G2-G2/M phases R-HSA-453274
Anchoring of the basal body to the plasma membrane R-HSA-5620912
E2F mediated regulation of DNA replication R-HSA-113510
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Cell Cycle, Mitotic R-HSA-69278
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Degradation R-HSA-6804757
Transcriptional Regulation by TP53 R-HSA-3700989
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Mitotic Metaphase and Anaphase R-HSA-2555396
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
G2/M DNA damage checkpoint R-HSA-69473
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
MASTL Facilitates Mitotic Progression R-HSA-2465910
Signal Transduction R-HSA-162582
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Organelle biogenesis and maintenance R-HSA-1852241
G2/M DNA replication checkpoint R-HSA-69478
Phosphorylation of the APC/C R-HSA-176412
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Regulation of TP53 Activity R-HSA-5633007
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
Centrosome maturation R-HSA-380287
Phosphorylation of Emi1 R-HSA-176417
Condensation of Prophase Chromosomes R-HSA-2299718
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
MAPK3 (ERK1) activation R-HSA-110056
MAPK family signaling cascades R-HSA-5683057
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Cilium Assembly R-HSA-5617833
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S-Specific Transcription R-HSA-69205
G2/M Transition R-HSA-69275
Cell Cycle Checkpoints R-HSA-69620
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of mitotic cell cycle R-HSA-453276
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
MAPK3 (ERK1) activation R-HSA-110056
Cilium Assembly R-HSA-5617833
G1/S Transition R-HSA-69206
Gene expression (Transcription) R-HSA-74160
Condensation of Prophase Chromosomes R-HSA-2299718
AURKA Activation by TPX2 R-HSA-8854518
Resolution of Sister Chromatid Cohesion R-HSA-2500257
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
Nuclear Envelope Breakdown R-HSA-2980766
Regulation of TP53 Degradation R-HSA-6804757
Centrosome maturation R-HSA-380287
Deubiquitination R-HSA-5688426
RNA Polymerase II Transcription R-HSA-73857
RAF-independent MAPK1/3 activation R-HSA-112409
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle Checkpoints R-HSA-69620
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Phosphorylation of Emi1 R-HSA-176417
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of TP53 Expression and Degradation R-HSA-6806003
G2/M Checkpoints R-HSA-69481
MAPK1/MAPK3 signaling R-HSA-5684996
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Mitotic Metaphase and Anaphase R-HSA-2555396
Transcriptional regulation by RUNX2 R-HSA-8878166
Phosphorylation of the APC/C R-HSA-176412
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Organelle biogenesis and maintenance R-HSA-1852241
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Loss of Nlp from mitotic centrosomes R-HSA-380259
Post-translational protein modification R-HSA-597592
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle R-HSA-1640170
Mitotic Anaphase R-HSA-68882
Mitotic Prophase R-HSA-68875
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
G2/M DNA damage checkpoint R-HSA-69473
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
G1/S-Specific Transcription R-HSA-69205
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Condensation of Prometaphase Chromosomes R-HSA-2514853
Ovarian tumor domain proteases R-HSA-5689896
Mitotic Prometaphase R-HSA-68877
Regulation of TP53 Activity R-HSA-5633007
MAPK family signaling cascades R-HSA-5683057
Mitotic G2-G2/M phases R-HSA-453274
Nuclear Envelope (NE) Reassembly R-HSA-2995410
MASTL Facilitates Mitotic Progression R-HSA-2465910
G2/M Transition R-HSA-69275
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Regulation of mitotic cell cycle R-HSA-453276
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional Regulation by TP53 R-HSA-3700989
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
G0 and Early G1 R-HSA-1538133
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic G1 phase and G1/S transition R-HSA-453279
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
E2F mediated regulation of DNA replication R-HSA-113510
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
G2/M DNA replication checkpoint R-HSA-69478
Regulation of TP53 Activity R-HSA-5633007
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Deubiquitination R-HSA-5688426
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Gene expression (Transcription) R-HSA-74160
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of TP53 Degradation R-HSA-6804757
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
RAF-independent MAPK1/3 activation R-HSA-112409
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Generic Transcription Pathway R-HSA-212436
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Mitotic G2-G2/M phases R-HSA-453274
G2/M DNA damage checkpoint R-HSA-69473
Cell Cycle R-HSA-1640170
Regulation of TP53 Expression and Degradation R-HSA-6806003
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Cilium Assembly R-HSA-5617833
Loss of Nlp from mitotic centrosomes R-HSA-380259
M Phase R-HSA-68886
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Metabolism of proteins R-HSA-392499
Phosphorylation of Emi1 R-HSA-176417
Organelle biogenesis and maintenance R-HSA-1852241
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Nuclear Envelope Breakdown R-HSA-2980766
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
MAPK3 (ERK1) activation R-HSA-110056
Depolymerisation of the Nuclear Lamina R-HSA-4419969
MASTL Facilitates Mitotic Progression R-HSA-2465910
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
E2F mediated regulation of DNA replication R-HSA-113510
MAPK family signaling cascades R-HSA-5683057
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Ovarian tumor domain proteases R-HSA-5689896
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Transcriptional regulation by RUNX2 R-HSA-8878166
AURKA Activation by TPX2 R-HSA-8854518
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
Condensation of Prophase Chromosomes R-HSA-2299718
G2/M Checkpoints R-HSA-69481
Transcriptional Regulation by TP53 R-HSA-3700989
G0 and Early G1 R-HSA-1538133
Mitotic Prophase R-HSA-68875
Signal Transduction R-HSA-162582
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic Prometaphase R-HSA-68877
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
G2/M DNA replication checkpoint R-HSA-69478
G1/S-Specific Transcription R-HSA-69205
Condensation of Prometaphase Chromosomes R-HSA-2514853
Centrosome maturation R-HSA-380287
G2/M Transition R-HSA-69275
MAPK6/MAPK4 signaling R-HSA-5687128
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Anaphase R-HSA-68882
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Post-translational protein modification R-HSA-597592
Phosphorylation of the APC/C R-HSA-176412
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Cell Cycle, Mitotic R-HSA-69278
Regulation of TP53 Degradation R-HSA-6804757
Cell Cycle, Mitotic R-HSA-69278
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Mitotic Prometaphase R-HSA-68877
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
RAF-independent MAPK1/3 activation R-HSA-112409
MAPK6/MAPK4 signaling R-HSA-5687128
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Phosphorylation of the APC/C R-HSA-176412
Regulation of TP53 Expression and Degradation R-HSA-6806003
Nuclear Envelope (NE) Reassembly R-HSA-2995410
AURKA Activation by TPX2 R-HSA-8854518
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Regulation of mitotic cell cycle R-HSA-453276
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Organelle biogenesis and maintenance R-HSA-1852241
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
MASTL Facilitates Mitotic Progression R-HSA-2465910
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Centrosome maturation R-HSA-380287
Mitotic Prophase R-HSA-68875
Cell Cycle Checkpoints R-HSA-69620
G2/M DNA replication checkpoint R-HSA-69478
Metabolism of proteins R-HSA-392499
G2/M Transition R-HSA-69275
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Nuclear Envelope Breakdown R-HSA-2980766
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Condensation of Prophase Chromosomes R-HSA-2299718
Regulation of TP53 Activity R-HSA-5633007
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Deubiquitination R-HSA-5688426
G2/M Checkpoints R-HSA-69481
Mitotic G2-G2/M phases R-HSA-453274
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
MAPK family signaling cascades R-HSA-5683057
G1/S-Specific Transcription R-HSA-69205
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Cell Cycle R-HSA-1640170
Condensation of Prometaphase Chromosomes R-HSA-2514853
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Transcriptional Regulation by TP53 R-HSA-3700989
G0 and Early G1 R-HSA-1538133
Cilium Assembly R-HSA-5617833
MAPK3 (ERK1) activation R-HSA-110056
Post-translational protein modification R-HSA-597592
G1/S Transition R-HSA-69206
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
M Phase R-HSA-68886
Loss of Nlp from mitotic centrosomes R-HSA-380259
G2/M DNA damage checkpoint R-HSA-69473
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
E2F mediated regulation of DNA replication R-HSA-113510
Gene expression (Transcription) R-HSA-74160
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Metaphase and Anaphase R-HSA-2555396
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX2 R-HSA-8878166
Ovarian tumor domain proteases R-HSA-5689896
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic G1 phase and G1/S transition R-HSA-453279
Phosphorylation of Emi1 R-HSA-176417
MAPK1/MAPK3 signaling R-HSA-5684996
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Mitotic Anaphase R-HSA-68882
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX2 R-HSA-8878166
G2/M DNA damage checkpoint R-HSA-69473
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Transcriptional Regulation by TP53 R-HSA-3700989
Cell Cycle Checkpoints R-HSA-69620
G1/S-Specific Transcription R-HSA-69205
Metabolism of proteins R-HSA-392499
Phosphorylation of the APC/C R-HSA-176412
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cilium Assembly R-HSA-5617833
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Mitotic G2-G2/M phases R-HSA-453274
Condensation of Prophase Chromosomes R-HSA-2299718
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Centrosome maturation R-HSA-380287
Cell Cycle, Mitotic R-HSA-69278
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Generic Transcription Pathway R-HSA-212436
Mitotic Prophase R-HSA-68875
Cell Cycle R-HSA-1640170
Nuclear Envelope (NE) Reassembly R-HSA-2995410
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Depolymerisation of the Nuclear Lamina R-HSA-4419969
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Nuclear Envelope Breakdown R-HSA-2980766
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
RNA Polymerase II Transcription R-HSA-73857
G2/M Transition R-HSA-69275
E2F mediated regulation of DNA replication R-HSA-113510
Mitotic Anaphase R-HSA-68882
Organelle biogenesis and maintenance R-HSA-1852241
Loss of Nlp from mitotic centrosomes R-HSA-380259
Gene expression (Transcription) R-HSA-74160
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
G2/M DNA replication checkpoint R-HSA-69478
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Ovarian tumor domain proteases R-HSA-5689896
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
MASTL Facilitates Mitotic Progression R-HSA-2465910
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Signal Transduction R-HSA-162582
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of TP53 Activity R-HSA-5633007
RAF-independent MAPK1/3 activation R-HSA-112409
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
Condensation of Prometaphase Chromosomes R-HSA-2514853
Regulation of TP53 Degradation R-HSA-6804757
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
G0 and Early G1 R-HSA-1538133
Mitotic Prometaphase R-HSA-68877
Post-translational protein modification R-HSA-597592
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Phosphorylation of Emi1 R-HSA-176417
Deubiquitination R-HSA-5688426
G1/S Transition R-HSA-69206
MAPK3 (ERK1) activation R-HSA-110056
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Regulation of mitotic cell cycle R-HSA-453276
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK1/MAPK3 signaling R-HSA-5684996
AURKA Activation by TPX2 R-HSA-8854518
G2/M DNA damage checkpoint R-HSA-69473
G2/M Checkpoints R-HSA-69481
G0 and Early G1 R-HSA-1538133
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Cell Cycle Checkpoints R-HSA-69620
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Deubiquitination R-HSA-5688426
Transcriptional Regulation by TP53 R-HSA-3700989
Depolymerisation of the Nuclear Lamina R-HSA-4419969
G2/M DNA replication checkpoint R-HSA-69478
Cilium Assembly R-HSA-5617833
Regulation of TP53 Expression and Degradation R-HSA-6806003
Mitotic Prometaphase R-HSA-68877
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Condensation of Prophase Chromosomes R-HSA-2299718
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Metabolism of proteins R-HSA-392499
RAF-independent MAPK1/3 activation R-HSA-112409
Regulation of TP53 Degradation R-HSA-6804757
Mitotic Prophase R-HSA-68875
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Cell Cycle, Mitotic R-HSA-69278
Mitotic Metaphase and Anaphase R-HSA-2555396
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Mitotic G1 phase and G1/S transition R-HSA-453279
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
G1/S Transition R-HSA-69206
Nuclear Envelope Breakdown R-HSA-2980766
MASTL Facilitates Mitotic Progression R-HSA-2465910
Loss of Nlp from mitotic centrosomes R-HSA-380259
Phosphorylation of the APC/C R-HSA-176412
G2/M Transition R-HSA-69275
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
E2F mediated regulation of DNA replication R-HSA-113510
Regulation of mitotic cell cycle R-HSA-453276
RNA Polymerase II Transcription R-HSA-73857
AURKA Activation by TPX2 R-HSA-8854518
Cell Cycle R-HSA-1640170
Organelle biogenesis and maintenance R-HSA-1852241
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK family signaling cascades R-HSA-5683057
G1/S-Specific Transcription R-HSA-69205
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Centrosome maturation R-HSA-380287
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ovarian tumor domain proteases R-HSA-5689896
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Anaphase R-HSA-68882
Post-translational protein modification R-HSA-597592
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Mitotic G2-G2/M phases R-HSA-453274
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Condensation of Prometaphase Chromosomes R-HSA-2514853
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Phosphorylation of Emi1 R-HSA-176417
MAPK3 (ERK1) activation R-HSA-110056
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Regulation of TP53 Activity R-HSA-5633007
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
MAPK1/MAPK3 signaling R-HSA-5684996
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Transcriptional regulation by RUNX2 R-HSA-8878166
Signal Transduction R-HSA-162582
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulation of mitotic cell cycle R-HSA-453276
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
RNA Polymerase II Transcription R-HSA-73857
Mitotic Prometaphase R-HSA-68877
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Deubiquitination R-HSA-5688426
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
AURKA Activation by TPX2 R-HSA-8854518
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Cell Cycle Checkpoints R-HSA-69620
G1/S Transition R-HSA-69206
Signal Transduction R-HSA-162582
RAF-independent MAPK1/3 activation R-HSA-112409
M Phase R-HSA-68886
E2F mediated regulation of DNA replication R-HSA-113510
Mitotic Prophase R-HSA-68875
Regulation of TP53 Expression and Degradation R-HSA-6806003
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Degradation R-HSA-6804757
MAPK3 (ERK1) activation R-HSA-110056
G2/M DNA replication checkpoint R-HSA-69478
MAPK family signaling cascades R-HSA-5683057
Mitotic G2-G2/M phases R-HSA-453274
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Mitotic Anaphase R-HSA-68882
Regulation of TP53 Activity R-HSA-5633007
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cilium Assembly R-HSA-5617833
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Post-translational protein modification R-HSA-597592
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Loss of Nlp from mitotic centrosomes R-HSA-380259
G2/M Transition R-HSA-69275
Nuclear Envelope (NE) Reassembly R-HSA-2995410
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Phosphorylation of the APC/C R-HSA-176412
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Anchoring of the basal body to the plasma membrane R-HSA-5620912
MAPK6/MAPK4 signaling R-HSA-5687128
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Phosphorylation of Emi1 R-HSA-176417
Transcriptional Regulation by TP53 R-HSA-3700989
MASTL Facilitates Mitotic Progression R-HSA-2465910
G0 and Early G1 R-HSA-1538133
Transcriptional regulation by RUNX2 R-HSA-8878166
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Resolution of Sister Chromatid Cohesion R-HSA-2500257
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
G1/S-Specific Transcription R-HSA-69205
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Centrosome maturation R-HSA-380287
Cell Cycle, Mitotic R-HSA-69278
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Nuclear Envelope Breakdown R-HSA-2980766
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Metabolism of proteins R-HSA-392499
G2/M Checkpoints R-HSA-69481
Organelle biogenesis and maintenance R-HSA-1852241
Condensation of Prometaphase Chromosomes R-HSA-2514853
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Condensation of Prophase Chromosomes R-HSA-2299718
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M DNA damage checkpoint R-HSA-69473
Ovarian tumor domain proteases R-HSA-5689896
MAPK1/MAPK3 signaling R-HSA-5684996
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Centrosome maturation R-HSA-380287
Metabolism of proteins R-HSA-392499
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Nuclear Envelope Breakdown R-HSA-2980766
AURKA Activation by TPX2 R-HSA-8854518
Cell Cycle R-HSA-1640170
Loss of Nlp from mitotic centrosomes R-HSA-380259
MASTL Facilitates Mitotic Progression R-HSA-2465910
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Mitotic G2-G2/M phases R-HSA-453274
G2/M Checkpoints R-HSA-69481
Ovarian tumor domain proteases R-HSA-5689896
Post-translational protein modification R-HSA-597592
MAPK6/MAPK4 signaling R-HSA-5687128
Cilium Assembly R-HSA-5617833
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
G2/M DNA replication checkpoint R-HSA-69478
Resolution of Sister Chromatid Cohesion R-HSA-2500257
G0 and Early G1 R-HSA-1538133
Mitotic Prophase R-HSA-68875
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of TP53 Activity R-HSA-5633007
M Phase R-HSA-68886
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Prometaphase R-HSA-68877
Signal Transduction R-HSA-162582
Condensation of Prometaphase Chromosomes R-HSA-2514853
Phosphorylation of the APC/C R-HSA-176412
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
RAF-independent MAPK1/3 activation R-HSA-112409
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Deubiquitination R-HSA-5688426
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
Organelle biogenesis and maintenance R-HSA-1852241
G1/S-Specific Transcription R-HSA-69205
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Mitotic G1 phase and G1/S transition R-HSA-453279
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulation of TP53 Expression and Degradation R-HSA-6806003
G2/M DNA damage checkpoint R-HSA-69473
MAPK family signaling cascades R-HSA-5683057
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic Anaphase R-HSA-68882
RNA Polymerase II Transcription R-HSA-73857
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle Checkpoints R-HSA-69620
MAPK3 (ERK1) activation R-HSA-110056
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of TP53 Degradation R-HSA-6804757
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Transcriptional Regulation by TP53 R-HSA-3700989
G1/S Transition R-HSA-69206
Condensation of Prophase Chromosomes R-HSA-2299718
Phosphorylation of Emi1 R-HSA-176417
E2F mediated regulation of DNA replication R-HSA-113510
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of mitotic cell cycle R-HSA-453276
G2/M Transition R-HSA-69275
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Organelle biogenesis and maintenance R-HSA-1852241
MAPK3 (ERK1) activation R-HSA-110056
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of TP53 Degradation R-HSA-6804757
Ovarian tumor domain proteases R-HSA-5689896
RAF-independent MAPK1/3 activation R-HSA-112409
G0 and Early G1 R-HSA-1538133
G2/M DNA replication checkpoint R-HSA-69478
Signal Transduction R-HSA-162582
Nuclear Envelope (NE) Reassembly R-HSA-2995410
E2F mediated regulation of DNA replication R-HSA-113510
G1/S Transition R-HSA-69206
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Depolymerisation of the Nuclear Lamina R-HSA-4419969
G1/S-Specific Transcription R-HSA-69205
M Phase R-HSA-68886
Post-translational protein modification R-HSA-597592
Cell Cycle R-HSA-1640170
Cell Cycle Checkpoints R-HSA-69620
G2/M Transition R-HSA-69275
Regulation of TP53 Expression and Degradation R-HSA-6806003
Mitotic Anaphase R-HSA-68882
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Deubiquitination R-HSA-5688426
Condensation of Prophase Chromosomes R-HSA-2299718
Regulation of TP53 Activity R-HSA-5633007
Phosphorylation of the APC/C R-HSA-176412
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Mitotic G1 phase and G1/S transition R-HSA-453279
Condensation of Prometaphase Chromosomes R-HSA-2514853
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Loss of Nlp from mitotic centrosomes R-HSA-380259
Mitotic Prometaphase R-HSA-68877
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Centrosome maturation R-HSA-380287
Regulation of mitotic cell cycle R-HSA-453276
Cilium Assembly R-HSA-5617833
MAPK1/MAPK3 signaling R-HSA-5684996
MASTL Facilitates Mitotic Progression R-HSA-2465910
Transcriptional Regulation by TP53 R-HSA-3700989
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
MAPK6/MAPK4 signaling R-HSA-5687128
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX2 R-HSA-8878166
G2/M DNA damage checkpoint R-HSA-69473
Mitotic G2-G2/M phases R-HSA-453274
Gene expression (Transcription) R-HSA-74160
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Mitotic Prophase R-HSA-68875
MAPK family signaling cascades R-HSA-5683057
AURKA Activation by TPX2 R-HSA-8854518
Mitotic Metaphase and Anaphase R-HSA-2555396
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Nuclear Envelope Breakdown R-HSA-2980766
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Phosphorylation of Emi1 R-HSA-176417
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
G2/M Checkpoints R-HSA-69481

Expression Atlas ENSG00000170312
NCBI gene (formerly Entrezgene) 983
GeneCards 1722
HGNC Symbol HGNC:1722
MIM gene 116940
UniProtKB Gene Name P06493
WikiGene 983
Gene: CCND1
Ensembl ID : ENSG00000110092
Description: cyclin D1
Gene Synonyms: BCL1,D11S287E,PRAD1,U21B31
1 APIs:
274 Possible Orthologues:

Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Diseases of mitotic cell cycle R-HSA-9675126
Pre-NOTCH Transcription and Translation R-HSA-1912408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Chromatin organization R-HSA-4839726
Transcriptional Regulation by VENTX R-HSA-8853884
Generic Transcription Pathway R-HSA-212436
RMTs methylate histone arginines R-HSA-3214858
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Disease R-HSA-1643685
Estrogen-dependent gene expression R-HSA-9018519
Pre-NOTCH Expression and Processing R-HSA-1912422
Cytokine Signaling in Immune system R-HSA-1280215
Extra-nuclear estrogen signaling R-HSA-9009391
Immune System R-HSA-168256
ESR-mediated signaling R-HSA-8939211
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Signaling by Nuclear Receptors R-HSA-9006931
G1 Phase R-HSA-69236
Cyclin D associated events in G1 R-HSA-69231
G1/S Transition R-HSA-69206
Cell Cycle, Mitotic R-HSA-69278
S Phase R-HSA-69242
Mitotic G1 phase and G1/S transition R-HSA-453279
RNA Polymerase II Transcription R-HSA-73857
PTK6 Regulates Cell Cycle R-HSA-8849470
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cell Cycle R-HSA-1640170
Signaling by NOTCH R-HSA-157118
Signaling by PTK6 R-HSA-8848021
Chromatin modifying enzymes R-HSA-3247509
RUNX3 regulates p14-ARF R-HSA-8951936
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Gene expression (Transcription) R-HSA-74160
RUNX3 regulates WNT signaling R-HSA-8951430
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX1 R-HSA-8878171
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX3 R-HSA-8878159
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Signaling by Interleukins R-HSA-449147
Disease R-HSA-1643685
Signaling by Nuclear Receptors R-HSA-9006931
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
S Phase R-HSA-69242
Gene expression (Transcription) R-HSA-74160
PTK6 Regulates Cell Cycle R-HSA-8849470
Transcriptional Regulation by VENTX R-HSA-8853884
RMTs methylate histone arginines R-HSA-3214858
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Cell Cycle R-HSA-1640170
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RUNX3 regulates WNT signaling R-HSA-8951430
Pre-NOTCH Expression and Processing R-HSA-1912422
Transcriptional regulation by RUNX3 R-HSA-8878159
G1 Phase R-HSA-69236
Transcriptional regulation by RUNX1 R-HSA-8878171
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cyclin E associated events during G1/S transition R-HSA-69202
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Signaling by NOTCH R-HSA-157118
RNA Polymerase II Transcription R-HSA-73857
Signaling by PTK6 R-HSA-8848021
G1/S Transition R-HSA-69206
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Chromatin modifying enzymes R-HSA-3247509
Pre-NOTCH Transcription and Translation R-HSA-1912408
Cell Cycle, Mitotic R-HSA-69278
Estrogen-dependent gene expression R-HSA-9018519
Extra-nuclear estrogen signaling R-HSA-9009391
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cyclin D associated events in G1 R-HSA-69231
Chromatin organization R-HSA-4839726
Generic Transcription Pathway R-HSA-212436
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
RUNX3 regulates p14-ARF R-HSA-8951936
Mitotic G1 phase and G1/S transition R-HSA-453279
Signal Transduction R-HSA-162582
ESR-mediated signaling R-HSA-8939211
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of mitotic cell cycle R-HSA-9675126
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Chromatin modifying enzymes R-HSA-3247509
S Phase R-HSA-69242
Mitotic G1 phase and G1/S transition R-HSA-453279
RMTs methylate histone arginines R-HSA-3214858
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Transcriptional regulation by RUNX1 R-HSA-8878171
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Transcriptional Regulation by VENTX R-HSA-8853884
ESR-mediated signaling R-HSA-8939211
Transcriptional regulation by RUNX3 R-HSA-8878159
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Diseases of mitotic cell cycle R-HSA-9675126
Generic Transcription Pathway R-HSA-212436
Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cytokine Signaling in Immune system R-HSA-1280215
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin D associated events in G1 R-HSA-69231
RUNX3 regulates WNT signaling R-HSA-8951430
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RUNX3 regulates p14-ARF R-HSA-8951936
Signaling by PTK6 R-HSA-8848021
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
G1 Phase R-HSA-69236
Extra-nuclear estrogen signaling R-HSA-9009391
Estrogen-dependent gene expression R-HSA-9018519
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
RNA Polymerase II Transcription R-HSA-73857
G1/S Transition R-HSA-69206
PTK6 Regulates Cell Cycle R-HSA-8849470
Signaling by NOTCH R-HSA-157118
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Pre-NOTCH Transcription and Translation R-HSA-1912408
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
Disease R-HSA-1643685
Pre-NOTCH Expression and Processing R-HSA-1912422
Chromatin organization R-HSA-4839726
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Cyclin D associated events in G1 R-HSA-69231
ESR-mediated signaling R-HSA-8939211
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
RUNX3 regulates p14-ARF R-HSA-8951936
RNA Polymerase II Transcription R-HSA-73857
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Transcriptional regulation by RUNX1 R-HSA-8878171
Chromatin organization R-HSA-4839726
RUNX3 regulates WNT signaling R-HSA-8951430
Generic Transcription Pathway R-HSA-212436
Estrogen-dependent gene expression R-HSA-9018519
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Diseases of mitotic cell cycle R-HSA-9675126
RMTs methylate histone arginines R-HSA-3214858
Signaling by Nuclear Receptors R-HSA-9006931
Pre-NOTCH Expression and Processing R-HSA-1912422
Chromatin modifying enzymes R-HSA-3247509
Signaling by NOTCH R-HSA-157118
G1/S Transition R-HSA-69206
S Phase R-HSA-69242
Gene expression (Transcription) R-HSA-74160
PTK6 Regulates Cell Cycle R-HSA-8849470
Disease R-HSA-1643685
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Transcriptional Regulation by VENTX R-HSA-8853884
Extra-nuclear estrogen signaling R-HSA-9009391
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Pre-NOTCH Transcription and Translation R-HSA-1912408
Transcriptional regulation by RUNX2 R-HSA-8878166
G1 Phase R-HSA-69236
Signaling by PTK6 R-HSA-8848021
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cell Cycle, Mitotic R-HSA-69278
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signal Transduction R-HSA-162582
Cell Cycle R-HSA-1640170
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by Interleukins R-HSA-449147
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
G1/S Transition R-HSA-69206
PTK6 Regulates Cell Cycle R-HSA-8849470
Estrogen-dependent gene expression R-HSA-9018519
Pre-NOTCH Expression and Processing R-HSA-1912422
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Transcriptional Regulation by VENTX R-HSA-8853884
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Gene expression (Transcription) R-HSA-74160
G1 Phase R-HSA-69236
Diseases of mitotic cell cycle R-HSA-9675126
RUNX3 regulates WNT signaling R-HSA-8951430
Mitotic G1 phase and G1/S transition R-HSA-453279
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Transcriptional regulation by RUNX3 R-HSA-8878159
ESR-mediated signaling R-HSA-8939211
RMTs methylate histone arginines R-HSA-3214858
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Disease R-HSA-1643685
RUNX3 regulates p14-ARF R-HSA-8951936
Pre-NOTCH Transcription and Translation R-HSA-1912408
Chromatin modifying enzymes R-HSA-3247509
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Transcriptional regulation by RUNX2 R-HSA-8878166
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by NOTCH R-HSA-157118
Chromatin organization R-HSA-4839726
Signaling by PTK6 R-HSA-8848021
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signal Transduction R-HSA-162582
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cyclin D associated events in G1 R-HSA-69231
Signaling by Nuclear Receptors R-HSA-9006931
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
S Phase R-HSA-69242
Extra-nuclear estrogen signaling R-HSA-9009391
Cytokine Signaling in Immune system R-HSA-1280215
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Cyclin E associated events during G1/S transition R-HSA-69202
Generic Transcription Pathway R-HSA-212436
Signaling by Interleukins R-HSA-449147
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by PTK6 R-HSA-8848021
Disease R-HSA-1643685
Transcriptional regulation by RUNX1 R-HSA-8878171
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by NOTCH R-HSA-157118
Transcriptional regulation by RUNX3 R-HSA-8878159
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Transcriptional Regulation by VENTX R-HSA-8853884
Chromatin organization R-HSA-4839726
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Pre-NOTCH Expression and Processing R-HSA-1912422
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1 Phase R-HSA-69236
RUNX3 regulates p14-ARF R-HSA-8951936
S Phase R-HSA-69242
ESR-mediated signaling R-HSA-8939211
Signaling by Nuclear Receptors R-HSA-9006931
Chromatin modifying enzymes R-HSA-3247509
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Immune System R-HSA-168256
Pre-NOTCH Transcription and Translation R-HSA-1912408
RMTs methylate histone arginines R-HSA-3214858
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle, Mitotic R-HSA-69278
G1/S Transition R-HSA-69206
Extra-nuclear estrogen signaling R-HSA-9009391
Cell Cycle R-HSA-1640170
Mitotic G1 phase and G1/S transition R-HSA-453279
Cyclin D associated events in G1 R-HSA-69231
RNA Polymerase II Transcription R-HSA-73857
Diseases of mitotic cell cycle R-HSA-9675126
Estrogen-dependent gene expression R-HSA-9018519
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
RUNX3 regulates WNT signaling R-HSA-8951430
Cyclin E associated events during G1/S transition R-HSA-69202
Gene expression (Transcription) R-HSA-74160
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
PTK6 Regulates Cell Cycle R-HSA-8849470
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Transcriptional regulation by RUNX3 R-HSA-8878159
Signal Transduction R-HSA-162582
RUNX3 regulates WNT signaling R-HSA-8951430
RMTs methylate histone arginines R-HSA-3214858
S Phase R-HSA-69242
G1/S Transition R-HSA-69206
RUNX3 regulates p14-ARF R-HSA-8951936
Cyclin E associated events during G1/S transition R-HSA-69202
Chromatin modifying enzymes R-HSA-3247509
PTK6 Regulates Cell Cycle R-HSA-8849470
Cell Cycle R-HSA-1640170
Signaling by NOTCH R-HSA-157118
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Pre-NOTCH Transcription and Translation R-HSA-1912408
Transcriptional Regulation by VENTX R-HSA-8853884
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Extra-nuclear estrogen signaling R-HSA-9009391
Immune System R-HSA-168256
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Gene expression (Transcription) R-HSA-74160
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Chromatin organization R-HSA-4839726
Generic Transcription Pathway R-HSA-212436
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of mitotic cell cycle R-HSA-9675126
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
ESR-mediated signaling R-HSA-8939211
Pre-NOTCH Expression and Processing R-HSA-1912422
Transcriptional regulation by RUNX2 R-HSA-8878166
Disease R-HSA-1643685
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by PTK6 R-HSA-8848021
Cyclin D associated events in G1 R-HSA-69231
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Cell Cycle, Mitotic R-HSA-69278
RNA Polymerase II Transcription R-HSA-73857
Estrogen-dependent gene expression R-HSA-9018519
Cytokine Signaling in Immune system R-HSA-1280215
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1 Phase R-HSA-69236
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by NOTCH R-HSA-157118
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Chromatin organization R-HSA-4839726
Mitotic G1 phase and G1/S transition R-HSA-453279
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Generic Transcription Pathway R-HSA-212436
RUNX3 regulates p14-ARF R-HSA-8951936
Chromatin modifying enzymes R-HSA-3247509
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Transcriptional regulation by RUNX3 R-HSA-8878159
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Disease R-HSA-1643685
Pre-NOTCH Transcription and Translation R-HSA-1912408
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX1 R-HSA-8878171
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
PTK6 Regulates Cell Cycle R-HSA-8849470
Cell Cycle, Mitotic R-HSA-69278
Gene expression (Transcription) R-HSA-74160
Signaling by Nuclear Receptors R-HSA-9006931
Cyclin D associated events in G1 R-HSA-69231
G1/S Transition R-HSA-69206
RMTs methylate histone arginines R-HSA-3214858
Transcriptional Regulation by VENTX R-HSA-8853884
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Immune System R-HSA-168256
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
S Phase R-HSA-69242
Signaling by PTK6 R-HSA-8848021
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Cyclin E associated events during G1/S transition R-HSA-69202
Signal Transduction R-HSA-162582
Pre-NOTCH Expression and Processing R-HSA-1912422
Estrogen-dependent gene expression R-HSA-9018519
Extra-nuclear estrogen signaling R-HSA-9009391
G1 Phase R-HSA-69236
RUNX3 regulates WNT signaling R-HSA-8951430
Diseases of mitotic cell cycle R-HSA-9675126
ESR-mediated signaling R-HSA-8939211
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Pre-NOTCH Transcription and Translation R-HSA-1912408
Signaling by Nuclear Receptors R-HSA-9006931
Cell Cycle R-HSA-1640170
Signaling by Interleukins R-HSA-449147
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Transcriptional regulation by RUNX1 R-HSA-8878171
Chromatin modifying enzymes R-HSA-3247509
Generic Transcription Pathway R-HSA-212436
Chromatin organization R-HSA-4839726
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Mitotic G1 phase and G1/S transition R-HSA-453279
Pre-NOTCH Expression and Processing R-HSA-1912422
Gene expression (Transcription) R-HSA-74160
Estrogen-dependent gene expression R-HSA-9018519
Diseases of mitotic cell cycle R-HSA-9675126
Extra-nuclear estrogen signaling R-HSA-9009391
Disease R-HSA-1643685
Cyclin E associated events during G1/S transition R-HSA-69202
RUNX3 regulates p14-ARF R-HSA-8951936
PTK6 Regulates Cell Cycle R-HSA-8849470
S Phase R-HSA-69242
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RUNX3 regulates WNT signaling R-HSA-8951430
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle, Mitotic R-HSA-69278
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
G1 Phase R-HSA-69236
ESR-mediated signaling R-HSA-8939211
Signaling by PTK6 R-HSA-8848021
RNA Polymerase II Transcription R-HSA-73857
G1/S Transition R-HSA-69206
Transcriptional Regulation by VENTX R-HSA-8853884
Signaling by NOTCH R-HSA-157118
Cyclin D associated events in G1 R-HSA-69231
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
RMTs methylate histone arginines R-HSA-3214858
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Transcriptional regulation by RUNX2 R-HSA-8878166
Immune System R-HSA-168256
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000110092
LRG display in Ensembl gene LRG_990
NCBI gene (formerly Entrezgene) 595
GeneCards 1582
HGNC Symbol HGNC:1582
MIM gene 168461
MIM morbid 254500
UniProtKB Gene Name Q6FI00
WikiGene 595
Gene: CDK4
Ensembl ID : ENSG00000135446
Description: cyclin dependent kinase 4
Gene Synonyms: PSK-J3
15 APIs:
227 Possible Orthologues:

Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Developmental Biology R-HSA-1266738
PTK6 Regulates Cell Cycle R-HSA-8849470
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RMTs methylate histone arginines R-HSA-3214858
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Meiotic recombination R-HSA-912446
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stimuli R-HSA-8953897
G1/S Transition R-HSA-69206
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Transcriptional regulation of granulopoiesis R-HSA-9616222
Chromatin modifying enzymes R-HSA-3247509
Cell Cycle R-HSA-1640170
Cyclin E associated events during G1/S transition R-HSA-69202
Signal Transduction R-HSA-162582
G1 Phase R-HSA-69236
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Diseases of cellular response to stress R-HSA-9675132
Cellular responses to stress R-HSA-2262752
Oncogene Induced Senescence R-HSA-2559585
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Reproduction R-HSA-1474165
Diseases of mitotic cell cycle R-HSA-9675126
S Phase R-HSA-69242
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
RNA Polymerase II Transcription R-HSA-73857
Chromatin organization R-HSA-4839726
Diseases of Cellular Senescence R-HSA-9630747
Cyclin D associated events in G1 R-HSA-69231
Signaling by PTK6 R-HSA-8848021
Meiosis R-HSA-1500620
Oxidative Stress Induced Senescence R-HSA-2559580
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Cellular Senescence R-HSA-2559583
Generic Transcription Pathway R-HSA-212436
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Gene expression (Transcription) R-HSA-74160
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX2 R-HSA-8878166
Diseases of mitotic cell cycle R-HSA-9675126
Signal Transduction R-HSA-162582
Cyclin E associated events during G1/S transition R-HSA-69202
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
G1 Phase R-HSA-69236
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cellular responses to stimuli R-HSA-8953897
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Cell Cycle, Mitotic R-HSA-69278
Signaling by PTK6 R-HSA-8848021
Cell Cycle R-HSA-1640170
Oxidative Stress Induced Senescence R-HSA-2559580
G1/S Transition R-HSA-69206
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cyclin D associated events in G1 R-HSA-69231
Cellular Senescence R-HSA-2559583
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
PTK6 Regulates Cell Cycle R-HSA-8849470
Meiotic recombination R-HSA-912446
Transcriptional regulation of granulopoiesis R-HSA-9616222
Meiosis R-HSA-1500620
Mitotic G1 phase and G1/S transition R-HSA-453279
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
RMTs methylate histone arginines R-HSA-3214858
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Gene expression (Transcription) R-HSA-74160
Oncogene Induced Senescence R-HSA-2559585
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Disease R-HSA-1643685
S Phase R-HSA-69242
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Chromatin modifying enzymes R-HSA-3247509
Diseases of Cellular Senescence R-HSA-9630747
Chromatin organization R-HSA-4839726
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RNA Polymerase II Transcription R-HSA-73857
Reproduction R-HSA-1474165
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Diseases of cellular response to stress R-HSA-9675132
Oxidative Stress Induced Senescence R-HSA-2559580
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Diseases of mitotic cell cycle R-HSA-9675126
Mitotic G1 phase and G1/S transition R-HSA-453279
Generic Transcription Pathway R-HSA-212436
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Disease R-HSA-1643685
Chromatin modifying enzymes R-HSA-3247509
Cyclin E associated events during G1/S transition R-HSA-69202
PTK6 Regulates Cell Cycle R-HSA-8849470
G1/S Transition R-HSA-69206
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cellular Senescence R-HSA-2559583
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Chromatin organization R-HSA-4839726
Signal Transduction R-HSA-162582
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Diseases of cellular response to stress R-HSA-9675132
RMTs methylate histone arginines R-HSA-3214858
G1 Phase R-HSA-69236
Meiosis R-HSA-1500620
RNA Polymerase II Transcription R-HSA-73857
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Gene expression (Transcription) R-HSA-74160
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Signaling by PTK6 R-HSA-8848021
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Meiotic recombination R-HSA-912446
Reproduction R-HSA-1474165
Cyclin D associated events in G1 R-HSA-69231
Cell Cycle R-HSA-1640170
Transcriptional regulation of granulopoiesis R-HSA-9616222
Oncogene Induced Senescence R-HSA-2559585
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Diseases of Cellular Senescence R-HSA-9630747
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
S Phase R-HSA-69242
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Reproduction R-HSA-1474165
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Gene expression (Transcription) R-HSA-74160
Diseases of mitotic cell cycle R-HSA-9675126
Mitotic G1 phase and G1/S transition R-HSA-453279
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
PTK6 Regulates Cell Cycle R-HSA-8849470
Signal Transduction R-HSA-162582
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Disease R-HSA-1643685
Oncogene Induced Senescence R-HSA-2559585
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Diseases of cellular response to stress R-HSA-9675132
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of Cellular Senescence R-HSA-9630747
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Chromatin organization R-HSA-4839726
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cyclin D associated events in G1 R-HSA-69231
Meiosis R-HSA-1500620
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Transcriptional regulation of granulopoiesis R-HSA-9616222
RNA Polymerase II Transcription R-HSA-73857
Meiotic recombination R-HSA-912446
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stimuli R-HSA-8953897
G1/S Transition R-HSA-69206
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
S Phase R-HSA-69242
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
RMTs methylate histone arginines R-HSA-3214858
Cell Cycle R-HSA-1640170
G1 Phase R-HSA-69236
Cellular Senescence R-HSA-2559583
Chromatin modifying enzymes R-HSA-3247509
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle, Mitotic R-HSA-69278
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Signaling by PTK6 R-HSA-8848021
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Cyclin E associated events during G1/S transition R-HSA-69202
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
Reproduction R-HSA-1474165
Cyclin D associated events in G1 R-HSA-69231
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Meiotic recombination R-HSA-912446
Diseases of cellular response to stress R-HSA-9675132
Transcriptional regulation of granulopoiesis R-HSA-9616222
Cellular responses to stress R-HSA-2262752
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Oncogene Induced Senescence R-HSA-2559585
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Cell Cycle R-HSA-1640170
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of Cellular Senescence R-HSA-9630747
Chromatin modifying enzymes R-HSA-3247509
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular Senescence R-HSA-2559583
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G1 Phase R-HSA-69236
RMTs methylate histone arginines R-HSA-3214858
Signal Transduction R-HSA-162582
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
PTK6 Regulates Cell Cycle R-HSA-8849470
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S Transition R-HSA-69206
Diseases of mitotic cell cycle R-HSA-9675126
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Signaling by PTK6 R-HSA-8848021
Meiosis R-HSA-1500620
Cellular responses to stimuli R-HSA-8953897
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Chromatin organization R-HSA-4839726
Oxidative Stress Induced Senescence R-HSA-2559580
Gene expression (Transcription) R-HSA-74160
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Cyclin E associated events during G1/S transition R-HSA-69202
G1/S Transition R-HSA-69206
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cellular Senescence R-HSA-2559583
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Reproduction R-HSA-1474165
Generic Transcription Pathway R-HSA-212436
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Meiosis R-HSA-1500620
Cell Cycle R-HSA-1640170
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Chromatin organization R-HSA-4839726
Cellular responses to stimuli R-HSA-8953897
G1 Phase R-HSA-69236
Diseases of mitotic cell cycle R-HSA-9675126
Diseases of cellular response to stress R-HSA-9675132
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Developmental Biology R-HSA-1266738
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Diseases of Cellular Senescence R-HSA-9630747
Cellular responses to stress R-HSA-2262752
Signaling by PTK6 R-HSA-8848021
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX2 R-HSA-8878166
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Oncogene Induced Senescence R-HSA-2559585
Transcriptional regulation of granulopoiesis R-HSA-9616222
Meiotic recombination R-HSA-912446
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Disease R-HSA-1643685
Chromatin modifying enzymes R-HSA-3247509
Oxidative Stress Induced Senescence R-HSA-2559580
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Cyclin D associated events in G1 R-HSA-69231
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
S Phase R-HSA-69242
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PTK6 Regulates Cell Cycle R-HSA-8849470
RNA Polymerase II Transcription R-HSA-73857
RMTs methylate histone arginines R-HSA-3214858
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S Transition R-HSA-69206
Oncogene Induced Senescence R-HSA-2559585
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Gene expression (Transcription) R-HSA-74160
Mitotic G1 phase and G1/S transition R-HSA-453279
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
RMTs methylate histone arginines R-HSA-3214858
Reproduction R-HSA-1474165
Signal Transduction R-HSA-162582
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Cellular responses to stress R-HSA-2262752
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin D associated events in G1 R-HSA-69231
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Chromatin organization R-HSA-4839726
PTK6 Regulates Cell Cycle R-HSA-8849470
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Diseases of cellular response to stress R-HSA-9675132
Developmental Biology R-HSA-1266738
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Cellular Senescence R-HSA-2559583
Meiotic recombination R-HSA-912446
Cellular responses to stimuli R-HSA-8953897
Chromatin modifying enzymes R-HSA-3247509
Transcriptional regulation of granulopoiesis R-HSA-9616222
Meiosis R-HSA-1500620
Diseases of mitotic cell cycle R-HSA-9675126
Diseases of Cellular Senescence R-HSA-9630747
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
S Phase R-HSA-69242
Signaling by PTK6 R-HSA-8848021
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G1 Phase R-HSA-69236
Oxidative Stress Induced Senescence R-HSA-2559580
Oxidative Stress Induced Senescence R-HSA-2559580
Diseases of cellular response to stress R-HSA-9675132
Cell Cycle, Mitotic R-HSA-69278
Meiosis R-HSA-1500620
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Diseases of Cellular Senescence R-HSA-9630747
S Phase R-HSA-69242
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by PTK6 R-HSA-8848021
G1/S Transition R-HSA-69206
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Cellular Senescence R-HSA-2559583
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Mitotic G1 phase and G1/S transition R-HSA-453279
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Cell Cycle R-HSA-1640170
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
Oncogene Induced Senescence R-HSA-2559585
Transcriptional regulation of granulopoiesis R-HSA-9616222
Chromatin organization R-HSA-4839726
Cyclin E associated events during G1/S transition R-HSA-69202
G1 Phase R-HSA-69236
Reproduction R-HSA-1474165
PTK6 Regulates Cell Cycle R-HSA-8849470
Chromatin modifying enzymes R-HSA-3247509
Meiotic recombination R-HSA-912446
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Cyclin D associated events in G1 R-HSA-69231
Developmental Biology R-HSA-1266738
RMTs methylate histone arginines R-HSA-3214858
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX2 R-HSA-8878166
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cellular responses to stimuli R-HSA-8953897
Diseases of mitotic cell cycle R-HSA-9675126
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Gene expression (Transcription) R-HSA-74160
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Signaling by PTK6 R-HSA-8848021
Developmental Biology R-HSA-1266738
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
PTK6 Regulates Cell Cycle R-HSA-8849470
Cyclin E associated events during G1/S transition R-HSA-69202
Meiotic recombination R-HSA-912446
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle, Mitotic R-HSA-69278
Oxidative Stress Induced Senescence R-HSA-2559580
Chromatin modifying enzymes R-HSA-3247509
Reproduction R-HSA-1474165
Diseases of Cellular Senescence R-HSA-9630747
S Phase R-HSA-69242
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
G1 Phase R-HSA-69236
Cellular responses to stimuli R-HSA-8953897
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Transcriptional regulation of granulopoiesis R-HSA-9616222
RNA Polymerase II Transcription R-HSA-73857
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Cellular Senescence R-HSA-2559583
Diseases of mitotic cell cycle R-HSA-9675126
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cell Cycle R-HSA-1640170
Cellular responses to stress R-HSA-2262752
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Meiosis R-HSA-1500620
RMTs methylate histone arginines R-HSA-3214858
Chromatin organization R-HSA-4839726
Signal Transduction R-HSA-162582
Oncogene Induced Senescence R-HSA-2559585
Diseases of cellular response to stress R-HSA-9675132
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
G1/S Transition R-HSA-69206
Cyclin D associated events in G1 R-HSA-69231
Transcriptional regulation by RUNX2 R-HSA-8878166
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cell Cycle R-HSA-1640170
Meiosis R-HSA-1500620
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Diseases of Cellular Senescence R-HSA-9630747
Cell Cycle, Mitotic R-HSA-69278
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cyclin D associated events in G1 R-HSA-69231
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Oncogene Induced Senescence R-HSA-2559585
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
RNA Polymerase II Transcription R-HSA-73857
RMTs methylate histone arginines R-HSA-3214858
PTK6 Regulates Cell Cycle R-HSA-8849470
G1 Phase R-HSA-69236
Gene expression (Transcription) R-HSA-74160
Chromatin organization R-HSA-4839726
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
S Phase R-HSA-69242
Meiotic recombination R-HSA-912446
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S Transition R-HSA-69206
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Transcriptional regulation of granulopoiesis R-HSA-9616222
Chromatin modifying enzymes R-HSA-3247509
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Reproduction R-HSA-1474165
Developmental Biology R-HSA-1266738
Signaling by PTK6 R-HSA-8848021
Cellular Senescence R-HSA-2559583
Diseases of cellular response to stress R-HSA-9675132
Cellular responses to stress R-HSA-2262752
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Signal Transduction R-HSA-162582
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Mitotic G1 phase and G1/S transition R-HSA-453279
Oxidative Stress Induced Senescence R-HSA-2559580
Generic Transcription Pathway R-HSA-212436
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stimuli R-HSA-8953897
Diseases of mitotic cell cycle R-HSA-9675126
Disease R-HSA-1643685

Expression Atlas ENSG00000135446
LRG display in Ensembl gene LRG_490
NCBI gene (formerly Entrezgene) 1019
GeneCards 1773
HGNC Symbol HGNC:1773
MIM gene 123829
MIM morbid 609048
UniProtKB Gene Name Q96BE9
WikiGene 1019
Gene: MAPK8
Ensembl ID : ENSG00000107643
Description: mitogen-activated protein kinase 8
Gene Synonyms: JNK,JNK1,PRKM8,SAPK1
3 APIs:
292 Possible Orthologues:

Cellular responses to stress R-HSA-2262752
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
DSCAM interactions R-HSA-376172
Disease R-HSA-1643685
Innate Immune System R-HSA-168249
DNA Double-Strand Break Repair R-HSA-5693532
Infectious disease R-HSA-5663205
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular responses to stimuli R-HSA-8953897
Activation of BMF and translocation to mitochondria R-HSA-139910
Activation of BIM and translocation to mitochondria R-HSA-111446
Killing mechanisms R-HSA-9664420
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
NRAGE signals death through JNK R-HSA-193648
Nervous system development R-HSA-9675108
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Axon guidance R-HSA-422475
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Programmed Cell Death R-HSA-5357801
Toll-like Receptor Cascades R-HSA-168898
Cytokine Signaling in Immune system R-HSA-1280215
DNA Double Strand Break Response R-HSA-5693606
Interleukin-1 family signaling R-HSA-446652
Netrin-1 signaling R-HSA-373752
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Activation of the AP-1 family of transcription factors R-HSA-450341
Developmental Biology R-HSA-1266738
Intrinsic Pathway for Apoptosis R-HSA-109606
DNA Repair R-HSA-73894
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88 cascade initiated on plasma membrane R-HSA-975871
Immune System R-HSA-168256
Leishmania infection R-HSA-9658195
Apoptosis R-HSA-109581
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular Senescence R-HSA-2559583
MyD88 dependent cascade initiated on endosome R-HSA-975155
MAP kinase activation R-HSA-450294
FCERI mediated MAPK activation R-HSA-2871796
Activation of BH3-only proteins R-HSA-114452
p75 NTR receptor-mediated signalling R-HSA-193704
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Interleukin-38 signaling R-HSA-9007892
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Death Receptor Signaling R-HSA-73887
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
NRIF signals cell death from the nucleus R-HSA-205043
Signal Transduction R-HSA-162582
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583
Activation of BH3-only proteins R-HSA-114452
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by Interleukins R-HSA-449147
Nervous system development R-HSA-9675108
NRIF signals cell death from the nucleus R-HSA-205043
FCERI mediated MAPK activation R-HSA-2871796
DNA Repair R-HSA-73894
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Infectious disease R-HSA-5663205
DNA Double-Strand Break Repair R-HSA-5693532
Netrin-1 signaling R-HSA-373752
Activation of BIM and translocation to mitochondria R-HSA-111446
Immune System R-HSA-168256
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
NRAGE signals death through JNK R-HSA-193648
Cellular responses to stress R-HSA-2262752
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Programmed Cell Death R-HSA-5357801
Death Receptor Signaling R-HSA-73887
Leishmania infection R-HSA-9658195
Interleukin-1 family signaling R-HSA-446652
Interleukin-38 signaling R-HSA-9007892
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Intrinsic Pathway for Apoptosis R-HSA-109606
MyD88 cascade initiated on plasma membrane R-HSA-975871
MAP kinase activation R-HSA-450294
Killing mechanisms R-HSA-9664420
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Developmental Biology R-HSA-1266738
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Activation of BMF and translocation to mitochondria R-HSA-139910
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Activation of the AP-1 family of transcription factors R-HSA-450341
Innate Immune System R-HSA-168249
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
p75 NTR receptor-mediated signalling R-HSA-193704
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Axon guidance R-HSA-422475
Apoptosis R-HSA-109581
MyD88 dependent cascade initiated on endosome R-HSA-975155
DSCAM interactions R-HSA-376172
DNA Double Strand Break Response R-HSA-5693606
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll-like Receptor Cascades R-HSA-168898
Cellular responses to stimuli R-HSA-8953897
Innate Immune System R-HSA-168249
MyD88 cascade initiated on plasma membrane R-HSA-975871
DSCAM interactions R-HSA-376172
Infectious disease R-HSA-5663205
NRAGE signals death through JNK R-HSA-193648
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
NRIF signals cell death from the nucleus R-HSA-205043
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cytokine Signaling in Immune system R-HSA-1280215
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Interleukins R-HSA-449147
DNA Double Strand Break Response R-HSA-5693606
MyD88-independent TLR4 cascade R-HSA-166166
Cellular responses to stress R-HSA-2262752
DNA Repair R-HSA-73894
Netrin-1 signaling R-HSA-373752
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Cellular responses to stimuli R-HSA-8953897
Disease R-HSA-1643685
Activation of the AP-1 family of transcription factors R-HSA-450341
Cellular Senescence R-HSA-2559583
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Intrinsic Pathway for Apoptosis R-HSA-109606
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Activation of BMF and translocation to mitochondria R-HSA-139910
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
DNA Double-Strand Break Repair R-HSA-5693532
Activation of BIM and translocation to mitochondria R-HSA-111446
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
Interleukin-1 family signaling R-HSA-446652
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
FCERI mediated MAPK activation R-HSA-2871796
Apoptosis R-HSA-109581
Nervous system development R-HSA-9675108
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Activation of BH3-only proteins R-HSA-114452
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Leishmania infection R-HSA-9658195
Immune System R-HSA-168256
Interleukin-38 signaling R-HSA-9007892
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Death Receptor Signaling R-HSA-73887
Programmed Cell Death R-HSA-5357801
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MAP kinase activation R-HSA-450294
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Developmental Biology R-HSA-1266738
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Killing mechanisms R-HSA-9664420
Killing mechanisms R-HSA-9664420
Activation of BIM and translocation to mitochondria R-HSA-111446
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Disease R-HSA-1643685
MyD88 dependent cascade initiated on endosome R-HSA-975155
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
DNA Double-Strand Break Repair R-HSA-5693532
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll-like Receptor Cascades R-HSA-168898
Netrin-1 signaling R-HSA-373752
MAP kinase activation R-HSA-450294
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Cellular Senescence R-HSA-2559583
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Oxidative Stress Induced Senescence R-HSA-2559580
Infectious disease R-HSA-5663205
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Activation of BMF and translocation to mitochondria R-HSA-139910
NRAGE signals death through JNK R-HSA-193648
Cellular responses to stress R-HSA-2262752
Intrinsic Pathway for Apoptosis R-HSA-109606
Apoptosis R-HSA-109581
Interleukin-38 signaling R-HSA-9007892
DNA Double Strand Break Response R-HSA-5693606
Leishmania infection R-HSA-9658195
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Activation of BH3-only proteins R-HSA-114452
DSCAM interactions R-HSA-376172
Interleukin-17 signaling R-HSA-448424
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
DNA Repair R-HSA-73894
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
FCERI mediated MAPK activation R-HSA-2871796
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
NRIF signals cell death from the nucleus R-HSA-205043
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Nervous system development R-HSA-9675108
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cytokine Signaling in Immune system R-HSA-1280215
Activation of the AP-1 family of transcription factors R-HSA-450341
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Developmental Biology R-HSA-1266738
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Programmed Cell Death R-HSA-5357801
Cellular Senescence R-HSA-2559583
Axon guidance R-HSA-422475
Oxidative Stress Induced Senescence R-HSA-2559580
Death Receptor Signaling R-HSA-73887
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
DNA Repair R-HSA-73894
Nervous system development R-HSA-9675108
Cellular responses to stress R-HSA-2262752
Netrin-1 signaling R-HSA-373752
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Innate Immune System R-HSA-168249
Activation of BIM and translocation to mitochondria R-HSA-111446
Programmed Cell Death R-HSA-5357801
Signal Transduction R-HSA-162582
Killing mechanisms R-HSA-9664420
Immune System R-HSA-168256
FCERI mediated MAPK activation R-HSA-2871796
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Apoptosis R-HSA-109581
Interleukin-17 signaling R-HSA-448424
MyD88-independent TLR4 cascade R-HSA-166166
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Leishmania infection R-HSA-9658195
Cytokine Signaling in Immune system R-HSA-1280215
NRAGE signals death through JNK R-HSA-193648
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
p75 NTR receptor-mediated signalling R-HSA-193704
MyD88 dependent cascade initiated on endosome R-HSA-975155
MAP kinase activation R-HSA-450294
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Intrinsic Pathway for Apoptosis R-HSA-109606
Disease R-HSA-1643685
Interleukin-38 signaling R-HSA-9007892
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll-like Receptor Cascades R-HSA-168898
Signaling by Interleukins R-HSA-449147
NRIF signals cell death from the nucleus R-HSA-205043
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of BMF and translocation to mitochondria R-HSA-139910
Developmental Biology R-HSA-1266738
DNA Double-Strand Break Repair R-HSA-5693532
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Infectious disease R-HSA-5663205
Activation of BH3-only proteins R-HSA-114452
Activation of the AP-1 family of transcription factors R-HSA-450341
Cellular responses to stimuli R-HSA-8953897
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
DNA Double Strand Break Response R-HSA-5693606
DSCAM interactions R-HSA-376172
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Signaling by Interleukins R-HSA-449147
Leishmania infection R-HSA-9658195
DNA Double-Strand Break Repair R-HSA-5693532
Activation of BMF and translocation to mitochondria R-HSA-139910
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
NRAGE signals death through JNK R-HSA-193648
Toll-like Receptor Cascades R-HSA-168898
Activation of the AP-1 family of transcription factors R-HSA-450341
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Interleukin-17 signaling R-HSA-448424
Netrin-1 signaling R-HSA-373752
MyD88 cascade initiated on plasma membrane R-HSA-975871
Axon guidance R-HSA-422475
Cellular Senescence R-HSA-2559583
Activation of BH3-only proteins R-HSA-114452
Apoptosis R-HSA-109581
Interleukin-38 signaling R-HSA-9007892
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Cytokine Signaling in Immune system R-HSA-1280215
MAP kinase activation R-HSA-450294
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Interleukin-1 family signaling R-HSA-446652
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88-independent TLR4 cascade R-HSA-166166
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Developmental Biology R-HSA-1266738
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
p75 NTR receptor-mediated signalling R-HSA-193704
DNA Repair R-HSA-73894
Intrinsic Pathway for Apoptosis R-HSA-109606
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Programmed Cell Death R-HSA-5357801
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stress R-HSA-2262752
Immune System R-HSA-168256
Killing mechanisms R-HSA-9664420
Nervous system development R-HSA-9675108
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Activation of BIM and translocation to mitochondria R-HSA-111446
DSCAM interactions R-HSA-376172
NRIF signals cell death from the nucleus R-HSA-205043
Infectious disease R-HSA-5663205
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Disease R-HSA-1643685
DNA Double Strand Break Response R-HSA-5693606
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
DNA Repair R-HSA-73894
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Innate Immune System R-HSA-168249
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by Interleukins R-HSA-449147
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Leishmania infection R-HSA-9658195
NRAGE signals death through JNK R-HSA-193648
Interleukin-38 signaling R-HSA-9007892
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Immune System R-HSA-168256
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DNA Double Strand Break Response R-HSA-5693606
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MyD88 dependent cascade initiated on endosome R-HSA-975155
Netrin-1 signaling R-HSA-373752
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Interleukin-1 family signaling R-HSA-446652
MyD88-independent TLR4 cascade R-HSA-166166
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
MAP kinase activation R-HSA-450294
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
DSCAM interactions R-HSA-376172
Apoptosis R-HSA-109581
Disease R-HSA-1643685
DNA Double-Strand Break Repair R-HSA-5693532
FCERI mediated MAPK activation R-HSA-2871796
Nervous system development R-HSA-9675108
Activation of BIM and translocation to mitochondria R-HSA-111446
Activation of BMF and translocation to mitochondria R-HSA-139910
NRIF signals cell death from the nucleus R-HSA-205043
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Programmed Cell Death R-HSA-5357801
Interleukin-17 signaling R-HSA-448424
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Killing mechanisms R-HSA-9664420
Cytokine Signaling in Immune system R-HSA-1280215
Cellular Senescence R-HSA-2559583
Activation of the AP-1 family of transcription factors R-HSA-450341
Oxidative Stress Induced Senescence R-HSA-2559580
Activation of BH3-only proteins R-HSA-114452
Cellular responses to stress R-HSA-2262752
Toll-like Receptor Cascades R-HSA-168898
Infectious disease R-HSA-5663205
Killing mechanisms R-HSA-9664420
Developmental Biology R-HSA-1266738
Intrinsic Pathway for Apoptosis R-HSA-109606
Interleukin-38 signaling R-HSA-9007892
p75 NTR receptor-mediated signalling R-HSA-193704
Cellular Senescence R-HSA-2559583
Activation of BMF and translocation to mitochondria R-HSA-139910
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Nervous system development R-HSA-9675108
DNA Repair R-HSA-73894
Programmed Cell Death R-HSA-5357801
Cellular responses to stress R-HSA-2262752
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Innate Immune System R-HSA-168249
Leishmania infection R-HSA-9658195
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Axon guidance R-HSA-422475
Netrin-1 signaling R-HSA-373752
Oxidative Stress Induced Senescence R-HSA-2559580
Disease R-HSA-1643685
DNA Double Strand Break Response R-HSA-5693606
DSCAM interactions R-HSA-376172
Cellular responses to stimuli R-HSA-8953897
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
FCERI mediated MAPK activation R-HSA-2871796
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
MyD88-independent TLR4 cascade R-HSA-166166
MAP kinase activation R-HSA-450294
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
NRIF signals cell death from the nucleus R-HSA-205043
DNA Double-Strand Break Repair R-HSA-5693532
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll-like Receptor Cascades R-HSA-168898
MyD88 dependent cascade initiated on endosome R-HSA-975155
Activation of BH3-only proteins R-HSA-114452
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Interleukin-17 signaling R-HSA-448424
Death Receptor Signaling R-HSA-73887
Activation of BIM and translocation to mitochondria R-HSA-111446
Interleukin-1 family signaling R-HSA-446652
Activation of the AP-1 family of transcription factors R-HSA-450341
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal Transduction R-HSA-162582
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Immune System R-HSA-168256
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
NRAGE signals death through JNK R-HSA-193648
Apoptosis R-HSA-109581
Killing mechanisms R-HSA-9664420
NRIF signals cell death from the nucleus R-HSA-205043
NRAGE signals death through JNK R-HSA-193648
p75 NTR receptor-mediated signalling R-HSA-193704
Activation of the AP-1 family of transcription factors R-HSA-450341
Immune System R-HSA-168256
DNA Double Strand Break Response R-HSA-5693606
MAP kinase activation R-HSA-450294
Activation of BH3-only proteins R-HSA-114452
Activation of BIM and translocation to mitochondria R-HSA-111446
Death Receptor Signaling R-HSA-73887
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by Interleukins R-HSA-449147
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
MyD88 cascade initiated on plasma membrane R-HSA-975871
Infectious disease R-HSA-5663205
Oxidative Stress Induced Senescence R-HSA-2559580
Programmed Cell Death R-HSA-5357801
Intrinsic Pathway for Apoptosis R-HSA-109606
Axon guidance R-HSA-422475
FCERI mediated MAPK activation R-HSA-2871796
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Activation of BMF and translocation to mitochondria R-HSA-139910
Interleukin-17 signaling R-HSA-448424
Disease R-HSA-1643685
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signal Transduction R-HSA-162582
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Nervous system development R-HSA-9675108
Leishmania infection R-HSA-9658195
Developmental Biology R-HSA-1266738
Interleukin-38 signaling R-HSA-9007892
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular Senescence R-HSA-2559583
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DNA Double-Strand Break Repair R-HSA-5693532
Apoptosis R-HSA-109581
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
DSCAM interactions R-HSA-376172
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Toll-like Receptor Cascades R-HSA-168898
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Cellular responses to stress R-HSA-2262752
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
DNA Repair R-HSA-73894
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Netrin-1 signaling R-HSA-373752
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Innate Immune System R-HSA-168249
Activation of BMF and translocation to mitochondria R-HSA-139910
Activation of BIM and translocation to mitochondria R-HSA-111446
Interleukin-1 family signaling R-HSA-446652
p75 NTR receptor-mediated signalling R-HSA-193704
Innate Immune System R-HSA-168249
Cellular responses to stress R-HSA-2262752
Activation of BH3-only proteins R-HSA-114452
Activation of the AP-1 family of transcription factors R-HSA-450341
DNA Double-Strand Break Repair R-HSA-5693532
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Interleukins R-HSA-449147
DNA Repair R-HSA-73894
Netrin-1 signaling R-HSA-373752
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll-like Receptor Cascades R-HSA-168898
NRAGE signals death through JNK R-HSA-193648
Disease R-HSA-1643685
MAP kinase activation R-HSA-450294
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Leishmania infection R-HSA-9658195
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
DSCAM interactions R-HSA-376172
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Killing mechanisms R-HSA-9664420
Intrinsic Pathway for Apoptosis R-HSA-109606
DNA Double Strand Break Response R-HSA-5693606
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal Transduction R-HSA-162582
MyD88-independent TLR4 cascade R-HSA-166166
Cellular Senescence R-HSA-2559583
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-38 signaling R-HSA-9007892
Apoptosis R-HSA-109581
NRIF signals cell death from the nucleus R-HSA-205043
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Programmed Cell Death R-HSA-5357801
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Nervous system development R-HSA-9675108
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Infectious disease R-HSA-5663205
Immune System R-HSA-168256
Developmental Biology R-HSA-1266738
Death Receptor Signaling R-HSA-73887
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88 dependent cascade initiated on endosome R-HSA-975155
Axon guidance R-HSA-422475
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-17 signaling R-HSA-448424
WNT5:FZD7-mediated leishmania damping R-HSA-9673324

Expression Atlas ENSG00000107643
NCBI gene (formerly Entrezgene) 5599
GeneCards 6881
HGNC Symbol HGNC:6881
MIM gene 601158
UniProtKB Gene Name P45983
WikiGene 5599
Gene: CDK6
Ensembl ID : ENSG00000105810
Description: cyclin dependent kinase 6
Gene Synonyms: PLSTIRE
9 APIs:
201 Possible Orthologues:

Cell Cycle, Mitotic R-HSA-69278
Cellular Senescence R-HSA-2559583
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of mitotic cell cycle R-HSA-9675126
Cell Cycle R-HSA-1640170
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Oxidative Stress Induced Senescence R-HSA-2559580
Gene expression (Transcription) R-HSA-74160
Oncogene Induced Senescence R-HSA-2559585
RNA Polymerase II Transcription R-HSA-73857
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Diseases of Cellular Senescence R-HSA-9630747
Cellular responses to stress R-HSA-2262752
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Cyclin D associated events in G1 R-HSA-69231
Disease R-HSA-1643685
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
G1 Phase R-HSA-69236
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Diseases of cellular response to stress R-HSA-9675132
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular responses to stress R-HSA-2262752
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Cellular responses to stimuli R-HSA-8953897
Cyclin D associated events in G1 R-HSA-69231
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Gene expression (Transcription) R-HSA-74160
Diseases of Cellular Senescence R-HSA-9630747
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Diseases of mitotic cell cycle R-HSA-9675126
RNA Polymerase II Transcription R-HSA-73857
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Diseases of cellular response to stress R-HSA-9675132
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Transcriptional regulation by RUNX1 R-HSA-8878171
Oxidative Stress Induced Senescence R-HSA-2559580
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
G1 Phase R-HSA-69236
Generic Transcription Pathway R-HSA-212436
Cellular Senescence R-HSA-2559583
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Oncogene Induced Senescence R-HSA-2559585
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Oncogene Induced Senescence R-HSA-2559585
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cellular responses to stimuli R-HSA-8953897
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Mitotic G1 phase and G1/S transition R-HSA-453279
Oxidative Stress Induced Senescence R-HSA-2559580
G1 Phase R-HSA-69236
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Diseases of mitotic cell cycle R-HSA-9675126
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
RNA Polymerase II Transcription R-HSA-73857
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular Senescence R-HSA-2559583
Diseases of Cellular Senescence R-HSA-9630747
Generic Transcription Pathway R-HSA-212436
Diseases of cellular response to stress R-HSA-9675132
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Gene expression (Transcription) R-HSA-74160
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Cyclin D associated events in G1 R-HSA-69231
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
G1 Phase R-HSA-69236
Cyclin D associated events in G1 R-HSA-69231
Generic Transcription Pathway R-HSA-212436
Cell Cycle, Mitotic R-HSA-69278
RNA Polymerase II Transcription R-HSA-73857
Cellular Senescence R-HSA-2559583
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular responses to stress R-HSA-2262752
Cell Cycle R-HSA-1640170
Oxidative Stress Induced Senescence R-HSA-2559580
Gene expression (Transcription) R-HSA-74160
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Diseases of cellular response to stress R-HSA-9675132
Diseases of Cellular Senescence R-HSA-9630747
Oncogene Induced Senescence R-HSA-2559585
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Cellular responses to stimuli R-HSA-8953897
Disease R-HSA-1643685
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Mitotic G1 phase and G1/S transition R-HSA-453279
Diseases of mitotic cell cycle R-HSA-9675126
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
RNA Polymerase II Transcription R-HSA-73857
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
G1 Phase R-HSA-69236
Generic Transcription Pathway R-HSA-212436
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Diseases of Cellular Senescence R-HSA-9630747
Cellular responses to stress R-HSA-2262752
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Cellular Senescence R-HSA-2559583
Oxidative Stress Induced Senescence R-HSA-2559580
Diseases of mitotic cell cycle R-HSA-9675126
Cyclin D associated events in G1 R-HSA-69231
Cellular responses to stimuli R-HSA-8953897
Diseases of cellular response to stress R-HSA-9675132
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX1 R-HSA-8878171
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Disease R-HSA-1643685
Gene expression (Transcription) R-HSA-74160
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Oncogene Induced Senescence R-HSA-2559585
Cell Cycle, Mitotic R-HSA-69278
Mitotic G1 phase and G1/S transition R-HSA-453279
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
RNA Polymerase II Transcription R-HSA-73857
Oncogene Induced Senescence R-HSA-2559585
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Transcriptional regulation by RUNX1 R-HSA-8878171
Oxidative Stress Induced Senescence R-HSA-2559580
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Diseases of Cellular Senescence R-HSA-9630747
Gene expression (Transcription) R-HSA-74160
Cellular responses to stimuli R-HSA-8953897
Generic Transcription Pathway R-HSA-212436
Regulation of RUNX1 Expression and Activity R-HSA-8934593
G1 Phase R-HSA-69236
Cellular responses to stress R-HSA-2262752
Mitotic G1 phase and G1/S transition R-HSA-453279
Diseases of mitotic cell cycle R-HSA-9675126
Disease R-HSA-1643685
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Cellular Senescence R-HSA-2559583
Cell Cycle, Mitotic R-HSA-69278
Diseases of cellular response to stress R-HSA-9675132
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cyclin D associated events in G1 R-HSA-69231
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Cell Cycle R-HSA-1640170
Cyclin D associated events in G1 R-HSA-69231
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Disease R-HSA-1643685
Cell Cycle R-HSA-1640170
Oxidative Stress Induced Senescence R-HSA-2559580
G1 Phase R-HSA-69236
Diseases of cellular response to stress R-HSA-9675132
Oncogene Induced Senescence R-HSA-2559585
Transcriptional regulation by RUNX1 R-HSA-8878171
Generic Transcription Pathway R-HSA-212436
Cellular Senescence R-HSA-2559583
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Cellular responses to stimuli R-HSA-8953897
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Diseases of mitotic cell cycle R-HSA-9675126
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Diseases of Cellular Senescence R-HSA-9630747
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Diseases of mitotic cell cycle R-HSA-9675126
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Cell Cycle R-HSA-1640170
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Cellular responses to stress R-HSA-2262752
Mitotic G1 phase and G1/S transition R-HSA-453279
Gene expression (Transcription) R-HSA-74160
Cyclin D associated events in G1 R-HSA-69231
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
G1 Phase R-HSA-69236
Cellular Senescence R-HSA-2559583
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of cellular response to stress R-HSA-9675132
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle, Mitotic R-HSA-69278
Oncogene Induced Senescence R-HSA-2559585
Oxidative Stress Induced Senescence R-HSA-2559580
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Disease R-HSA-1643685
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Diseases of Cellular Senescence R-HSA-9630747
Cellular responses to stress R-HSA-2262752
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Diseases of cellular response to stress R-HSA-9675132
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
G1 Phase R-HSA-69236
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Cellular Senescence R-HSA-2559583
Cell Cycle, Mitotic R-HSA-69278
Mitotic G1 phase and G1/S transition R-HSA-453279
Oxidative Stress Induced Senescence R-HSA-2559580
Oncogene Induced Senescence R-HSA-2559585
Diseases of Cellular Senescence R-HSA-9630747
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Generic Transcription Pathway R-HSA-212436
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Cyclin D associated events in G1 R-HSA-69231
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX1 R-HSA-8878171
Disease R-HSA-1643685
Diseases of mitotic cell cycle R-HSA-9675126
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Cellular responses to stimuli R-HSA-8953897
G1 Phase R-HSA-69236
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Cellular Senescence R-HSA-2559583
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Cyclin D associated events in G1 R-HSA-69231
Diseases of mitotic cell cycle R-HSA-9675126
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Oxidative Stress Induced Senescence R-HSA-2559580
Mitotic G1 phase and G1/S transition R-HSA-453279
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
RNA Polymerase II Transcription R-HSA-73857
Diseases of cellular response to stress R-HSA-9675132
Disease R-HSA-1643685
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Oncogene Induced Senescence R-HSA-2559585
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Diseases of Cellular Senescence R-HSA-9630747
Transcriptional regulation by RUNX1 R-HSA-8878171
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897

Expression Atlas ENSG00000105810
LRG display in Ensembl gene LRG_991
NCBI gene (formerly Entrezgene) 1021
GeneCards 1777
HGNC Symbol HGNC:1777
MIM gene 603368
MIM morbid 616080
UniProtKB Gene Name Q00534
WikiGene 1021
Gene: MAPK3
Ensembl ID : ENSG00000102882
Description: mitogen-activated protein kinase 3
Gene Synonyms: ERK1,P44ERK1,P44MAPK,PRKM3
6 APIs:
199 Possible Orthologues:

ERK/MAPK targets R-HSA-198753
M Phase R-HSA-68886
Disease R-HSA-1643685
Signaling by RAS mutants R-HSA-6802949
Signaling by NODAL R-HSA-1181150
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
G alpha (q) signalling events R-HSA-416476
ESR-mediated signaling R-HSA-8939211
Signal attenuation R-HSA-74749
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Growth hormone receptor signaling R-HSA-982772
GPCR downstream signalling R-HSA-388396
Negative regulation of MAPK pathway R-HSA-5675221
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR3 R-HSA-5654741
Signaling by TGF-beta Receptor Complex R-HSA-170834
ISG15 antiviral mechanism R-HSA-1169408
RUNX2 regulates bone development R-HSA-8941326
Toll-like Receptor Cascades R-HSA-168898
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Negative regulation of FGFR3 signaling R-HSA-5654732
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Disease R-HSA-1643685
Signaling by Nuclear Receptors R-HSA-9006931
Activation of the AP-1 family of transcription factors R-HSA-450341
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by FGFR1 R-HSA-5654736
Signaling by Activin R-HSA-1502540
Signaling by NTRKs R-HSA-166520
L1CAM interactions R-HSA-373760
MAPK3 (ERK1) activation R-HSA-110056
Interferon Signaling R-HSA-913531
Frs2-mediated activation R-HSA-170968
Signalling to ERKs R-HSA-187687
RNA Polymerase I Promoter Opening R-HSA-73728
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ALK in cancer R-HSA-9700206
Cell Cycle, Mitotic R-HSA-69278
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
NCAM signaling for neurite out-growth R-HSA-375165
Cellular responses to stress R-HSA-2262752
Signaling downstream of RAS mutants R-HSA-9649948
Negative regulation of the PI3K/AKT network R-HSA-199418
MyD88 cascade initiated on plasma membrane R-HSA-975871
Formation of apoptosome R-HSA-111458
ERK/MAPK targets R-HSA-198753
Response of Mtb to phagocytosis R-HSA-9637690
M Phase R-HSA-68886
Post NMDA receptor activation events R-HSA-438064
Transcriptional regulation by RUNX2 R-HSA-8878166
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Suppression of apoptosis R-HSA-9635465
Cellular Senescence R-HSA-2559583
Nervous system development R-HSA-9675108
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Hemostasis R-HSA-109582
Intrinsic Pathway for Apoptosis R-HSA-109606
RNA Polymerase I Promoter Clearance R-HSA-73854
Regulation of the apoptosome activity R-HSA-9627069
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-17 signaling R-HSA-448424
Innate Immune System R-HSA-168249
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Neuronal System R-HSA-112316
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF-independent MAPK1/3 activation R-HSA-112409
Leishmania phagocytosis R-HSA-9664417
MAPK family signaling cascades R-HSA-5683057
Generic Transcription Pathway R-HSA-212436
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Immune System R-HSA-168256
Signaling by TGFB family members R-HSA-9006936
Signal transduction by L1 R-HSA-445144
Signaling by FGFR4 R-HSA-5654743
Oxidative Stress Induced Senescence R-HSA-2559580
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Cytochrome c-mediated apoptotic response R-HSA-111461
MAP kinase activation R-HSA-450294
Insulin receptor signalling cascade R-HSA-74751
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Insulin receptor R-HSA-74752
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RNA Polymerase I Transcription R-HSA-73864
MyD88-independent TLR4 cascade R-HSA-166166
Transmission across Chemical Synapses R-HSA-112315
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by Interleukins R-HSA-449147
Signaling by FGFR2 R-HSA-5654738
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Leishmania infection R-HSA-9658195
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Apoptotic factor-mediated response R-HSA-111471
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by GPCR R-HSA-372790
RHO GTPase Effectors R-HSA-195258
Oncogene Induced Senescence R-HSA-2559585
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
PTEN Regulation R-HSA-6807070
Developmental Biology R-HSA-1266738
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Cellular response to heat stress R-HSA-3371556
NPAS4 regulates expression of target genes R-HSA-9768919
ERKs are inactivated R-HSA-202670
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Programmed Cell Death R-HSA-5357801
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MAP2K and MAPK activation R-HSA-5674135
RAF/MAP kinase cascade R-HSA-5673001
FCGR3A-mediated phagocytosis R-HSA-9664422
Negative regulation of FGFR1 signaling R-HSA-5654726
Parasite infection R-HSA-9664407
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
Signaling by MAP2K mutants R-HSA-9652169
Axon guidance R-HSA-422475
Infection with Mycobacterium tuberculosis R-HSA-9635486
Oncogenic MAPK signaling R-HSA-6802957
Apoptosis R-HSA-109581
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cell Cycle R-HSA-1640170
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Prolonged ERK activation events R-HSA-169893
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Negative regulation of FGFR4 signaling R-HSA-5654733
FCERI mediated MAPK activation R-HSA-2871796
Infectious disease R-HSA-5663205
Negative regulation of FGFR2 signaling R-HSA-5654727
Mitotic Prophase R-HSA-68875
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Signaling by FGFR R-HSA-190236
Transcriptional Regulation by NPAS4 R-HSA-9634815
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by NTRK1 (TRKA) R-HSA-187037
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
RSK activation R-HSA-444257
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Frs2-mediated activation R-HSA-170968
Cell Cycle, Mitotic R-HSA-69278
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by RAS mutants R-HSA-6802949
Interleukin-17 signaling R-HSA-448424
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Signaling by GPCR R-HSA-372790
Growth hormone receptor signaling R-HSA-982772
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by FGFR3 R-HSA-5654741
Suppression of apoptosis R-HSA-9635465
Transcriptional regulation by RUNX2 R-HSA-8878166
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
M Phase R-HSA-68886
Cellular response to heat stress R-HSA-3371556
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RSK activation R-HSA-444257
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by TGFB family members R-HSA-9006936
Signal transduction by L1 R-HSA-445144
FCGR3A-mediated phagocytosis R-HSA-9664422
Response of Mtb to phagocytosis R-HSA-9637690
Regulation of PTEN gene transcription R-HSA-8943724
Negative feedback regulation of MAPK pathway R-HSA-5674499
MAP2K and MAPK activation R-HSA-5674135
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Rho GTPases R-HSA-194315
Signaling by Insulin receptor R-HSA-74752
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Axon guidance R-HSA-422475
Programmed Cell Death R-HSA-5357801
NPAS4 regulates expression of target genes R-HSA-9768919
Neuronal System R-HSA-112316
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Hemostasis R-HSA-109582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Immune System R-HSA-168256
Cytochrome c-mediated apoptotic response R-HSA-111461
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal attenuation R-HSA-74749
Formation of apoptosome R-HSA-111458
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by ALK in cancer R-HSA-9700206
Signaling by Nuclear Receptors R-HSA-9006931
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cellular Senescence R-HSA-2559583
Signaling by MAP2K mutants R-HSA-9652169
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Transmission across Chemical Synapses R-HSA-112315
Signaling by FGFR R-HSA-190236
FCERI mediated MAPK activation R-HSA-2871796
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Cellular responses to stress R-HSA-2262752
Signaling by FGFR2 R-HSA-5654738
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
ERK/MAPK targets R-HSA-198753
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by NTRKs R-HSA-166520
Transcriptional Regulation by NPAS4 R-HSA-9634815
GPCR downstream signalling R-HSA-388396
MyD88-independent TLR4 cascade R-HSA-166166
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
PTEN Regulation R-HSA-6807070
Cell Cycle R-HSA-1640170
Negative regulation of FGFR1 signaling R-HSA-5654726
L1CAM interactions R-HSA-373760
Negative regulation of FGFR3 signaling R-HSA-5654732
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signalling to ERKs R-HSA-187687
Post NMDA receptor activation events R-HSA-438064
Oncogenic MAPK signaling R-HSA-6802957
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Interferon Signaling R-HSA-913531
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
RNA Polymerase I Promoter Opening R-HSA-73728
Activation of the AP-1 family of transcription factors R-HSA-450341
RNA Polymerase I Promoter Clearance R-HSA-73854
ERKs are inactivated R-HSA-202670
MyD88 dependent cascade initiated on endosome R-HSA-975155
ESR-mediated signaling R-HSA-8939211
Negative regulation of FGFR4 signaling R-HSA-5654733
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Activin R-HSA-1502540
Signaling by NTRK1 (TRKA) R-HSA-187037
Gene expression (Transcription) R-HSA-74160
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Negative regulation of FGFR2 signaling R-HSA-5654727
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK family signaling cascades R-HSA-5683057
Signaling by Interleukins R-HSA-449147
Insulin receptor signalling cascade R-HSA-74751
G alpha (q) signalling events R-HSA-416476
Signaling by NODAL R-HSA-1181150
PIP3 activates AKT signaling R-HSA-1257604
Regulation of the apoptosome activity R-HSA-9627069
Signaling by FGFR4 R-HSA-5654743
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK1/MAPK3 signaling R-HSA-5684996
NCAM signaling for neurite out-growth R-HSA-375165
Oncogene Induced Senescence R-HSA-2559585
Apoptosis R-HSA-109581
RNA Polymerase I Transcription R-HSA-73864
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Intrinsic Pathway for Apoptosis R-HSA-109606
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Parasite infection R-HSA-9664407
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Infection with Mycobacterium tuberculosis R-HSA-9635486
RHO GTPase Effectors R-HSA-195258
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Innate Immune System R-HSA-168249
Negative regulation of MAPK pathway R-HSA-5675221
Spry regulation of FGF signaling R-HSA-1295596
Leishmania phagocytosis R-HSA-9664417
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by FGFR1 R-HSA-5654736
MAP kinase activation R-HSA-450294
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by ALK fusions and activated point mutants R-HSA-9725370
ISG15 antiviral mechanism R-HSA-1169408
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Cytokine Signaling in Immune system R-HSA-1280215
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Negative regulation of the PI3K/AKT network R-HSA-199418
Toll-like Receptor Cascades R-HSA-168898
RAF/MAP kinase cascade R-HSA-5673001
Leishmania infection R-HSA-9658195
Generic Transcription Pathway R-HSA-212436
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Apoptotic factor-mediated response R-HSA-111471
MAPK3 (ERK1) activation R-HSA-110056
Platelet activation, signaling and aggregation R-HSA-76002
RUNX2 regulates bone development R-HSA-8941326
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Prolonged ERK activation events R-HSA-169893
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Growth hormone receptor signaling R-HSA-982772
MyD88 cascade initiated on plasma membrane R-HSA-975871
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
ISG15 antiviral mechanism R-HSA-1169408
Negative regulation of FGFR4 signaling R-HSA-5654733
Platelet activation, signaling and aggregation R-HSA-76002
RNA Polymerase I Promoter Opening R-HSA-73728
Parasite infection R-HSA-9664407
Axon guidance R-HSA-422475
RNA Polymerase I Promoter Clearance R-HSA-73854
Negative feedback regulation of MAPK pathway R-HSA-5674499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Prolonged ERK activation events R-HSA-169893
Toll-like Receptor Cascades R-HSA-168898
Signal transduction by L1 R-HSA-445144
Cellular Senescence R-HSA-2559583
NCAM signaling for neurite out-growth R-HSA-375165
L1CAM interactions R-HSA-373760
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Gene expression (Transcription) R-HSA-74160
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Signaling by NTRK1 (TRKA) R-HSA-187037
Cell Cycle R-HSA-1640170
Formation of apoptosome R-HSA-111458
Interleukin-17 signaling R-HSA-448424
Transcriptional regulation by RUNX2 R-HSA-8878166
NPAS4 regulates expression of target genes R-HSA-9768919
Hemostasis R-HSA-109582
Cellular responses to stimuli R-HSA-8953897
RAF-independent MAPK1/3 activation R-HSA-112409
Signalling to ERKs R-HSA-187687
Signaling by FGFR2 R-HSA-5654738
Negative regulation of MAPK pathway R-HSA-5675221
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Transmission across Chemical Synapses R-HSA-112315
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signaling by Insulin receptor R-HSA-74752
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Cytokine Signaling in Immune system R-HSA-1280215
ERK/MAPK targets R-HSA-198753
Signaling by Activin R-HSA-1502540
Interferon Signaling R-HSA-913531
Signaling by GPCR R-HSA-372790
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stress R-HSA-2262752
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Rho GTPases R-HSA-194315
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Transcriptional Regulation by NPAS4 R-HSA-9634815
RHO GTPase Effectors R-HSA-195258
Signal attenuation R-HSA-74749
Oncogenic MAPK signaling R-HSA-6802957
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling downstream of RAS mutants R-HSA-9649948
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAP kinase activation R-HSA-450294
Signaling by RAS mutants R-HSA-6802949
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Leishmania infection R-HSA-9658195
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by FGFR4 R-HSA-5654743
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by NODAL R-HSA-1181150
RUNX2 regulates bone development R-HSA-8941326
ERKs are inactivated R-HSA-202670
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by MAP2K mutants R-HSA-9652169
Signaling by FGFR1 R-HSA-5654736
Signaling by TGF-beta Receptor Complex R-HSA-170834
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Extra-nuclear estrogen signaling R-HSA-9009391
Nervous system development R-HSA-9675108
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Oncogene Induced Senescence R-HSA-2559585
Cell Cycle, Mitotic R-HSA-69278
Disease R-HSA-1643685
Signaling by FGFR3 R-HSA-5654741
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
PIP3 activates AKT signaling R-HSA-1257604
ESR-mediated signaling R-HSA-8939211
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RSK activation R-HSA-444257
Immune System R-HSA-168256
RAF/MAP kinase cascade R-HSA-5673001
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by NTRKs R-HSA-166520
Apoptotic factor-mediated response R-HSA-111471
Negative regulation of FGFR1 signaling R-HSA-5654726
Leishmania phagocytosis R-HSA-9664417
Programmed Cell Death R-HSA-5357801
Signaling by TGFB family members R-HSA-9006936
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Innate Immune System R-HSA-168249
Neuronal System R-HSA-112316
Oxidative Stress Induced Senescence R-HSA-2559580
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RNA Polymerase II Transcription R-HSA-73857
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Cytochrome c-mediated apoptotic response R-HSA-111461
M Phase R-HSA-68886
Post NMDA receptor activation events R-HSA-438064
G alpha (q) signalling events R-HSA-416476
Spry regulation of FGF signaling R-HSA-1295596
FCERI mediated MAPK activation R-HSA-2871796
PTEN Regulation R-HSA-6807070
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Cellular response to heat stress R-HSA-3371556
Suppression of apoptosis R-HSA-9635465
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Response of Mtb to phagocytosis R-HSA-9637690
MAPK3 (ERK1) activation R-HSA-110056
Signaling by RAF1 mutants R-HSA-9656223
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MAP2K and MAPK activation R-HSA-5674135
Signaling by ALK in cancer R-HSA-9700206
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR R-HSA-190236
Intracellular signaling by second messengers R-HSA-9006925
Regulation of the apoptosome activity R-HSA-9627069
Infectious disease R-HSA-5663205
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
RNA Polymerase I Transcription R-HSA-73864
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Negative regulation of FGFR2 signaling R-HSA-5654727
FCGR3A-mediated phagocytosis R-HSA-9664422
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Developmental Biology R-HSA-1266738
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Apoptosis R-HSA-109581
Signaling by ALK fusions and activated point mutants R-HSA-9725370
MAPK family signaling cascades R-HSA-5683057
Frs2-mediated activation R-HSA-170968
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
Mitotic Prophase R-HSA-68875
Negative regulation of the PI3K/AKT network R-HSA-199418
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Regulation of the apoptosome activity R-HSA-9627069
Signaling by RAF1 mutants R-HSA-9656223
Parasite infection R-HSA-9664407
Signaling by NTRKs R-HSA-166520
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Generic Transcription Pathway R-HSA-212436
Signaling by NODAL R-HSA-1181150
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
FCGR3A-mediated phagocytosis R-HSA-9664422
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Apoptosis R-HSA-109581
Oncogenic MAPK signaling R-HSA-6802957
Signaling by MAP2K mutants R-HSA-9652169
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Signaling by FGFR4 R-HSA-5654743
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Apoptotic factor-mediated response R-HSA-111471
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by FGFR2 R-HSA-5654738
Negative feedback regulation of MAPK pathway R-HSA-5674499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NCAM signaling for neurite out-growth R-HSA-375165
RNA Polymerase I Transcription R-HSA-73864
Cellular response to heat stress R-HSA-3371556
Neuronal System R-HSA-112316
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MyD88 cascade initiated on plasma membrane R-HSA-975871
RNA Polymerase I Promoter Clearance R-HSA-73854
Cell Cycle, Mitotic R-HSA-69278
RSK activation R-HSA-444257
Programmed Cell Death R-HSA-5357801
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signal transduction by L1 R-HSA-445144
Infectious disease R-HSA-5663205
Formation of apoptosome R-HSA-111458
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RUNX2 regulates osteoblast differentiation R-HSA-8940973
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by Insulin receptor R-HSA-74752
Regulation of PTEN gene transcription R-HSA-8943724
Interferon Signaling R-HSA-913531
Oxidative Stress Induced Senescence R-HSA-2559580
NPAS4 regulates expression of target genes R-HSA-9768919
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling downstream of RAS mutants R-HSA-9649948
Frs2-mediated activation R-HSA-170968
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 dependent cascade initiated on endosome R-HSA-975155
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
MAP kinase activation R-HSA-450294
RNA Polymerase I Promoter Opening R-HSA-73728
Signaling by BRAF and RAF1 fusions R-HSA-6802952
ISG15 antiviral mechanism R-HSA-1169408
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
ERKs are inactivated R-HSA-202670
Leishmania phagocytosis R-HSA-9664417
Leishmania infection R-HSA-9658195
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FGFR R-HSA-190236
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
L1CAM interactions R-HSA-373760
Insulin receptor signalling cascade R-HSA-74751
MAPK family signaling cascades R-HSA-5683057
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular responses to stimuli R-HSA-8953897
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signal attenuation R-HSA-74749
Intracellular signaling by second messengers R-HSA-9006925
Growth hormone receptor signaling R-HSA-982772
Signaling by NTRK1 (TRKA) R-HSA-187037
Prolonged ERK activation events R-HSA-169893
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAP2K and MAPK activation R-HSA-5674135
RAF/MAP kinase cascade R-HSA-5673001
Hemostasis R-HSA-109582
Toll-like Receptor Cascades R-HSA-168898
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by Rho GTPases R-HSA-194315
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Axon guidance R-HSA-422475
MAPK3 (ERK1) activation R-HSA-110056
Signaling by FGFR3 R-HSA-5654741
ESR-mediated signaling R-HSA-8939211
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
M Phase R-HSA-68886
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RHO GTPase Effectors R-HSA-195258
Mitotic Prophase R-HSA-68875
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by RAS mutants R-HSA-6802949
Platelet activation, signaling and aggregation R-HSA-76002
Innate Immune System R-HSA-168249
Post NMDA receptor activation events R-HSA-438064
Negative regulation of FGFR3 signaling R-HSA-5654732
Oncogene Induced Senescence R-HSA-2559585
Negative regulation of FGFR2 signaling R-HSA-5654727
Signalling to ERKs R-HSA-187687
Cellular Senescence R-HSA-2559583
Signaling by ALK in cancer R-HSA-9700206
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Activin R-HSA-1502540
Transcriptional regulation by RUNX2 R-HSA-8878166
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by FGFR1 R-HSA-5654736
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Interleukins R-HSA-449147
Negative regulation of MAPK pathway R-HSA-5675221
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Transmission across Chemical Synapses R-HSA-112315
FCERI mediated MAPK activation R-HSA-2871796
Suppression of apoptosis R-HSA-9635465
RUNX2 regulates bone development R-HSA-8941326
Signaling by TGF-beta Receptor Complex R-HSA-170834
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Response of Mtb to phagocytosis R-HSA-9637690
Transcriptional Regulation by NPAS4 R-HSA-9634815
RAF-independent MAPK1/3 activation R-HSA-112409
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
ERK/MAPK targets R-HSA-198753
Signaling by TGFB family members R-HSA-9006936
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Spry regulation of FGF signaling R-HSA-1295596
PIP3 activates AKT signaling R-HSA-1257604
Activation of the AP-1 family of transcription factors R-HSA-450341
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
RNA Polymerase II Transcription R-HSA-73857
Extra-nuclear estrogen signaling R-HSA-9009391
Interleukin-17 signaling R-HSA-448424
FCERI mediated MAPK activation R-HSA-2871796
Developmental Biology R-HSA-1266738
Signaling by NTRK1 (TRKA) R-HSA-187037
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR4 signaling R-HSA-5654733
Prolonged ERK activation events R-HSA-169893
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cellular responses to stress R-HSA-2262752
Signaling by GPCR R-HSA-372790
Negative feedback regulation of MAPK pathway R-HSA-5674499
RNA Polymerase I Transcription R-HSA-73864
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by TGFB family members R-HSA-9006936
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll-like Receptor Cascades R-HSA-168898
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
M Phase R-HSA-68886
Signaling by FGFR4 R-HSA-5654743
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Apoptosis R-HSA-109581
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of NMDA receptors and postsynaptic events R-HSA-442755
ESR-mediated signaling R-HSA-8939211
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Activin R-HSA-1502540
Cytokine Signaling in Immune system R-HSA-1280215
Oncogene Induced Senescence R-HSA-2559585
MAP kinase activation R-HSA-450294
Immune System R-HSA-168256
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MAPK3 (ERK1) activation R-HSA-110056
Neuronal System R-HSA-112316
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MAPK family signaling cascades R-HSA-5683057
Signaling by TGF-beta Receptor Complex R-HSA-170834
Negative regulation of MAPK pathway R-HSA-5675221
RUNX2 regulates bone development R-HSA-8941326
Interferon Signaling R-HSA-913531
RAF-independent MAPK1/3 activation R-HSA-112409
Generic Transcription Pathway R-HSA-212436
Signaling by FGFR R-HSA-190236
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Infection with Mycobacterium tuberculosis R-HSA-9635486
Negative regulation of FGFR1 signaling R-HSA-5654726
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Cellular responses to stimuli R-HSA-8953897
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular Senescence R-HSA-2559583
MyD88 cascade initiated on plasma membrane R-HSA-975871
Intracellular signaling by second messengers R-HSA-9006925
Signalling to ERKs R-HSA-187687
Signal attenuation R-HSA-74749
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Leishmania infection R-HSA-9658195
Regulation of the apoptosome activity R-HSA-9627069
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
MyD88 dependent cascade initiated on endosome R-HSA-975155
Hemostasis R-HSA-109582
Signaling by Nuclear Receptors R-HSA-9006931
Frs2-mediated activation R-HSA-170968
Post NMDA receptor activation events R-HSA-438064
Transmission across Chemical Synapses R-HSA-112315
Signaling by NODAL R-HSA-1181150
Suppression of apoptosis R-HSA-9635465
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by FGFR3 R-HSA-5654741
Infectious disease R-HSA-5663205
Signaling by ALK in cancer R-HSA-9700206
GPCR downstream signalling R-HSA-388396
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Transcriptional regulation by RUNX2 R-HSA-8878166
RSK activation R-HSA-444257
FCGR3A-mediated phagocytosis R-HSA-9664422
Oncogenic MAPK signaling R-HSA-6802957
Formation of apoptosome R-HSA-111458
Negative regulation of FGFR2 signaling R-HSA-5654727
Regulation of PTEN gene transcription R-HSA-8943724
Programmed Cell Death R-HSA-5357801
Signal transduction by L1 R-HSA-445144
Interleukin-17 signaling R-HSA-448424
Signaling by Rho GTPases R-HSA-194315
Cell Cycle, Mitotic R-HSA-69278
Insulin receptor signalling cascade R-HSA-74751
Negative regulation of the PI3K/AKT network R-HSA-199418
MAP2K and MAPK activation R-HSA-5674135
NPAS4 regulates expression of target genes R-HSA-9768919
Transcriptional Regulation by NPAS4 R-HSA-9634815
Activation of the AP-1 family of transcription factors R-HSA-450341
Disease R-HSA-1643685
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Negative regulation of FGFR3 signaling R-HSA-5654732
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by RAF1 mutants R-HSA-9656223
Intrinsic Pathway for Apoptosis R-HSA-109606
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Extra-nuclear estrogen signaling R-HSA-9009391
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Response of Mtb to phagocytosis R-HSA-9637690
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MAPK1/MAPK3 signaling R-HSA-5684996
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Mitotic Prophase R-HSA-68875
RHO GTPase Effectors R-HSA-195258
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by MAP2K mutants R-HSA-9652169
MyD88-independent TLR4 cascade R-HSA-166166
RAF/MAP kinase cascade R-HSA-5673001
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Oxidative Stress Induced Senescence R-HSA-2559580
Apoptotic factor-mediated response R-HSA-111471
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Axon guidance R-HSA-422475
L1CAM interactions R-HSA-373760
Leishmania phagocytosis R-HSA-9664417
Signal Transduction R-HSA-162582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Spry regulation of FGF signaling R-HSA-1295596
ERKs are inactivated R-HSA-202670
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by NTRKs R-HSA-166520
Growth hormone receptor signaling R-HSA-982772
Signaling by Insulin receptor R-HSA-74752
Parasite infection R-HSA-9664407
Signaling by RAS mutants R-HSA-6802949
Innate Immune System R-HSA-168249
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by FGFR2 R-HSA-5654738
Cytochrome c-mediated apoptotic response R-HSA-111461
RNA Polymerase I Promoter Opening R-HSA-73728
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by FGFR1 R-HSA-5654736
Nervous system development R-HSA-9675108
ISG15 antiviral mechanism R-HSA-1169408
Cell Cycle R-HSA-1640170
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Transcriptional Regulation by NPAS4 R-HSA-9634815
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
ESR-mediated signaling R-HSA-8939211
MAP2K and MAPK activation R-HSA-5674135
Developmental Biology R-HSA-1266738
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
RNA Polymerase I Promoter Opening R-HSA-73728
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Interleukin-17 signaling R-HSA-448424
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Neuronal System R-HSA-112316
RSK activation R-HSA-444257
MyD88-independent TLR4 cascade R-HSA-166166
Post NMDA receptor activation events R-HSA-438064
Signaling by Insulin receptor R-HSA-74752
RUNX2 regulates bone development R-HSA-8941326
Oxidative Stress Induced Senescence R-HSA-2559580
Activation of the AP-1 family of transcription factors R-HSA-450341
Activation of NMDA receptors and postsynaptic events R-HSA-442755
M Phase R-HSA-68886
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Activin R-HSA-1502540
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signal attenuation R-HSA-74749
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Interferon Signaling R-HSA-913531
Growth hormone receptor signaling R-HSA-982772
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by FGFR4 R-HSA-5654743
Signaling by RAF1 mutants R-HSA-9656223
Oncogenic MAPK signaling R-HSA-6802957
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Spry regulation of FGF signaling R-HSA-1295596
MAP kinase activation R-HSA-450294
Apoptotic factor-mediated response R-HSA-111471
RNA Polymerase II Transcription R-HSA-73857
Infection with Mycobacterium tuberculosis R-HSA-9635486
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
FCGR3A-mediated phagocytosis R-HSA-9664422
GPCR downstream signalling R-HSA-388396
Signaling by FGFR3 R-HSA-5654741
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Innate Immune System R-HSA-168249
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR1 R-HSA-5654736
ERK/MAPK targets R-HSA-198753
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Extra-nuclear estrogen signaling R-HSA-9009391
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RUNX2 regulates osteoblast differentiation R-HSA-8940973
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by NTRKs R-HSA-166520
Leishmania infection R-HSA-9658195
Programmed Cell Death R-HSA-5357801
Parasite infection R-HSA-9664407
MyD88 dependent cascade initiated on endosome R-HSA-975155
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by TGFB family members R-HSA-9006936
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NCAM signaling for neurite out-growth R-HSA-375165
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
L1CAM interactions R-HSA-373760
Signal Transduction R-HSA-162582
Frs2-mediated activation R-HSA-170968
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll-like Receptor Cascades R-HSA-168898
Negative regulation of MAPK pathway R-HSA-5675221
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
FCERI mediated MAPK activation R-HSA-2871796
Signaling by MAP2K mutants R-HSA-9652169
Signaling by ALK in cancer R-HSA-9700206
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Cellular Senescence R-HSA-2559583
Infectious disease R-HSA-5663205
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Generic Transcription Pathway R-HSA-212436
Intrinsic Pathway for Apoptosis R-HSA-109606
Mitotic Prophase R-HSA-68875
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by GPCR R-HSA-372790
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling downstream of RAS mutants R-HSA-9649948
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RNA Polymerase I Transcription R-HSA-73864
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by RAS mutants R-HSA-6802949
ERKs are inactivated R-HSA-202670
Cell Cycle, Mitotic R-HSA-69278
Regulation of PTEN gene transcription R-HSA-8943724
Negative regulation of FGFR3 signaling R-HSA-5654732
MAPK family signaling cascades R-HSA-5683057
Negative regulation of FGFR1 signaling R-HSA-5654726
RAF/MAP kinase cascade R-HSA-5673001
Formation of apoptosome R-HSA-111458
Signaling by Nuclear Receptors R-HSA-9006931
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by NTRK1 (TRKA) R-HSA-187037
Immune System R-HSA-168256
Signaling by TGF-beta Receptor Complex R-HSA-170834
PIP3 activates AKT signaling R-HSA-1257604
MAPK3 (ERK1) activation R-HSA-110056
RAF-independent MAPK1/3 activation R-HSA-112409
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
MAPK1/MAPK3 signaling R-HSA-5684996
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cytochrome c-mediated apoptotic response R-HSA-111461
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of the apoptosome activity R-HSA-9627069
Signal transduction by L1 R-HSA-445144
Hemostasis R-HSA-109582
Oncogene Induced Senescence R-HSA-2559585
RHO GTPase Effectors R-HSA-195258
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Suppression of apoptosis R-HSA-9635465
Signaling by FGFR R-HSA-190236
Apoptosis R-HSA-109581
G alpha (q) signalling events R-HSA-416476
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Nervous system development R-HSA-9675108
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
PTEN Regulation R-HSA-6807070
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by FGFR2 R-HSA-5654738
Prolonged ERK activation events R-HSA-169893
Negative regulation of FGFR4 signaling R-HSA-5654733
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular response to heat stress R-HSA-3371556
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by Rho GTPases R-HSA-194315
Signaling by NODAL R-HSA-1181150
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Transmission across Chemical Synapses R-HSA-112315
Leishmania phagocytosis R-HSA-9664417
Response of Mtb to phagocytosis R-HSA-9637690
Cellular responses to stimuli R-HSA-8953897
Signalling to ERKs R-HSA-187687
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
FCGR3A-mediated phagocytosis R-HSA-9664422
Prolonged ERK activation events R-HSA-169893
Programmed Cell Death R-HSA-5357801
Signaling by NTRKs R-HSA-166520
Negative regulation of FGFR2 signaling R-HSA-5654727
Neuronal System R-HSA-112316
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Activin R-HSA-1502540
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by FGFR4 R-HSA-5654743
Apoptotic factor-mediated response R-HSA-111471
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Oncogene Induced Senescence R-HSA-2559585
Response of Mtb to phagocytosis R-HSA-9637690
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
ERKs are inactivated R-HSA-202670
Apoptosis R-HSA-109581
RHO GTPase Effectors R-HSA-195258
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by ALK fusions and activated point mutants R-HSA-9725370
RNA Polymerase II Transcription R-HSA-73857
MyD88 dependent cascade initiated on endosome R-HSA-975155
Formation of apoptosome R-HSA-111458
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Extra-nuclear estrogen signaling R-HSA-9009391
RSK activation R-HSA-444257
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Toll-like Receptor Cascades R-HSA-168898
Cell Cycle R-HSA-1640170
Innate Immune System R-HSA-168249
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Axon guidance R-HSA-422475
Signaling by ALK in cancer R-HSA-9700206
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
L1CAM interactions R-HSA-373760
Infection with Mycobacterium tuberculosis R-HSA-9635486
RNA Polymerase I Promoter Opening R-HSA-73728
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Frs2-mediated activation R-HSA-170968
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Hemostasis R-HSA-109582
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR3 R-HSA-5654741
ESR-mediated signaling R-HSA-8939211
Signaling by FGFR R-HSA-190236
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
RNA Polymerase I Transcription R-HSA-73864
Signaling by RAF1 mutants R-HSA-9656223
MAPK family signaling cascades R-HSA-5683057
Cellular Senescence R-HSA-2559583
Platelet activation, signaling and aggregation R-HSA-76002
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by NODAL R-HSA-1181150
Signalling to ERKs R-HSA-187687
Nervous system development R-HSA-9675108
Negative regulation of MAPK pathway R-HSA-5675221
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cell Cycle, Mitotic R-HSA-69278
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G alpha (q) signalling events R-HSA-416476
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Signaling by FGFR1 R-HSA-5654736
Insulin receptor signalling cascade R-HSA-74751
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Spry regulation of FGF signaling R-HSA-1295596
Cellular responses to stress R-HSA-2262752
GPCR downstream signalling R-HSA-388396
Intracellular signaling by second messengers R-HSA-9006925
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
MAP2K and MAPK activation R-HSA-5674135
Signaling by FGFR2 R-HSA-5654738
RUNX2 regulates bone development R-HSA-8941326
Activation of the AP-1 family of transcription factors R-HSA-450341
Suppression of apoptosis R-HSA-9635465
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-17 signaling R-HSA-448424
Disease R-HSA-1643685
Leishmania infection R-HSA-9658195
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signal attenuation R-HSA-74749
Signaling by Nuclear Receptors R-HSA-9006931
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by RAS mutants R-HSA-6802949
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK3 (ERK1) activation R-HSA-110056
Signaling by Rho GTPases R-HSA-194315
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Regulation of the apoptosome activity R-HSA-9627069
Growth hormone receptor signaling R-HSA-982772
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by MAP2K mutants R-HSA-9652169
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
ERK/MAPK targets R-HSA-198753
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Leishmania phagocytosis R-HSA-9664417
Cellular responses to stimuli R-HSA-8953897
Signaling by Interleukins R-HSA-449147
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signal transduction by L1 R-HSA-445144
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by GPCR R-HSA-372790
Negative feedback regulation of MAPK pathway R-HSA-5674499
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Negative regulation of FGFR1 signaling R-HSA-5654726
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RNA Polymerase I Promoter Clearance R-HSA-73854
Parasite infection R-HSA-9664407
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by TGFB family members R-HSA-9006936
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated MAPK activation R-HSA-2871796
MAP kinase activation R-HSA-450294
Transcriptional Regulation by NPAS4 R-HSA-9634815
Negative regulation of the PI3K/AKT network R-HSA-199418
Interferon Signaling R-HSA-913531
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intrinsic Pathway for Apoptosis R-HSA-109606
Post NMDA receptor activation events R-HSA-438064
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Infectious disease R-HSA-5663205
Transmission across Chemical Synapses R-HSA-112315
Regulation of PTEN gene transcription R-HSA-8943724
Oncogenic MAPK signaling R-HSA-6802957
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Extra-nuclear estrogen signaling R-HSA-9009391
Interferon Signaling R-HSA-913531
Transmission across Chemical Synapses R-HSA-112315
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR1 R-HSA-5654736
Apoptotic factor-mediated response R-HSA-111471
Signal transduction by L1 R-HSA-445144
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Rho GTPases R-HSA-194315
Leishmania phagocytosis R-HSA-9664417
MAPK family signaling cascades R-HSA-5683057
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
RNA Polymerase I Promoter Opening R-HSA-73728
Signaling by NODAL R-HSA-1181150
Immune System R-HSA-168256
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Post NMDA receptor activation events R-HSA-438064
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Hemostasis R-HSA-109582
Suppression of apoptosis R-HSA-9635465
Activation of the AP-1 family of transcription factors R-HSA-450341
PTEN Regulation R-HSA-6807070
Programmed Cell Death R-HSA-5357801
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by NTRKs R-HSA-166520
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Oncogenic MAPK signaling R-HSA-6802957
RNA Polymerase I Transcription R-HSA-73864
Interleukin-17 signaling R-HSA-448424
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR4 R-HSA-5654743
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Negative regulation of the PI3K/AKT network R-HSA-199418
Platelet activation, signaling and aggregation R-HSA-76002
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Insulin receptor R-HSA-74752
FCERI mediated MAPK activation R-HSA-2871796
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Frs2-mediated activation R-HSA-170968
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling downstream of RAS mutants R-HSA-9649948
Developmental Biology R-HSA-1266738
Negative regulation of FGFR1 signaling R-HSA-5654726
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Nuclear Receptors R-HSA-9006931
Mitotic Prophase R-HSA-68875
Neuronal System R-HSA-112316
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Growth hormone receptor signaling R-HSA-982772
MAP kinase activation R-HSA-450294
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll-like Receptor Cascades R-HSA-168898
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
MAPK3 (ERK1) activation R-HSA-110056
Signaling by FGFR3 R-HSA-5654741
Signaling by FGFR2 R-HSA-5654738
Parasite infection R-HSA-9664407
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by ALK in cancer R-HSA-9700206
Signaling by TGFB family members R-HSA-9006936
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by RAS mutants R-HSA-6802949
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
RUNX2 regulates bone development R-HSA-8941326
L1CAM interactions R-HSA-373760
Gene expression (Transcription) R-HSA-74160
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Prolonged ERK activation events R-HSA-169893
ERK/MAPK targets R-HSA-198753
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Oncogene Induced Senescence R-HSA-2559585
Negative feedback regulation of MAPK pathway R-HSA-5674499
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular response to heat stress R-HSA-3371556
Transcriptional regulation by RUNX2 R-HSA-8878166
Response of Mtb to phagocytosis R-HSA-9637690
Intracellular signaling by second messengers R-HSA-9006925
RAF-independent MAPK1/3 activation R-HSA-112409
RSK activation R-HSA-444257
Signaling by MAP2K mutants R-HSA-9652169
Nervous system development R-HSA-9675108
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Negative regulation of FGFR2 signaling R-HSA-5654727
MyD88 cascade initiated on plasma membrane R-HSA-975871
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of FGFR4 signaling R-HSA-5654733
Oxidative Stress Induced Senescence R-HSA-2559580
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR R-HSA-190236
Signaling by GPCR R-HSA-372790
Signaling by TGF-beta Receptor Complex R-HSA-170834
GPCR downstream signalling R-HSA-388396
Negative regulation of MAPK pathway R-HSA-5675221
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
M Phase R-HSA-68886
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Apoptosis R-HSA-109581
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Leishmania infection R-HSA-9658195
Intrinsic Pathway for Apoptosis R-HSA-109606
MyD88-independent TLR4 cascade R-HSA-166166
MAP2K and MAPK activation R-HSA-5674135
ERKs are inactivated R-HSA-202670
ESR-mediated signaling R-HSA-8939211
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
NPAS4 regulates expression of target genes R-HSA-9768919
Cellular responses to stimuli R-HSA-8953897
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Cellular Senescence R-HSA-2559583
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signalling to ERKs R-HSA-187687
Spry regulation of FGF signaling R-HSA-1295596
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Innate Immune System R-HSA-168249
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Signaling by NTRK1 (TRKA) R-HSA-187037
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
PIP3 activates AKT signaling R-HSA-1257604
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Formation of apoptosome R-HSA-111458
Regulation of the apoptosome activity R-HSA-9627069
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
RHO GTPase Effectors R-HSA-195258
MAPK1/MAPK3 signaling R-HSA-5684996
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signal attenuation R-HSA-74749
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of PTEN gene transcription R-HSA-8943724
Infection with Mycobacterium tuberculosis R-HSA-9635486
G alpha (q) signalling events R-HSA-416476
Signaling by Activin R-HSA-1502540
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR4 R-HSA-5654743
RNA Polymerase I Promoter Clearance R-HSA-73854
Activation of the AP-1 family of transcription factors R-HSA-450341
Infection with Mycobacterium tuberculosis R-HSA-9635486
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
MyD88-independent TLR4 cascade R-HSA-166166
PIP3 activates AKT signaling R-HSA-1257604
Regulation of HSF1-mediated heat shock response R-HSA-3371453
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by MAP2K mutants R-HSA-9652169
RSK activation R-HSA-444257
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MAPK family signaling cascades R-HSA-5683057
Signaling by NTRKs R-HSA-166520
Signaling by FGFR3 R-HSA-5654741
Developmental Biology R-HSA-1266738
Oncogenic MAPK signaling R-HSA-6802957
Suppression of apoptosis R-HSA-9635465
ERK/MAPK targets R-HSA-198753
Spry regulation of FGF signaling R-HSA-1295596
Disease R-HSA-1643685
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cell Cycle, Mitotic R-HSA-69278
Signaling by NTRK1 (TRKA) R-HSA-187037
Programmed Cell Death R-HSA-5357801
Axon guidance R-HSA-422475
Signaling downstream of RAS mutants R-HSA-9649948
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Oncogene Induced Senescence R-HSA-2559585
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Extra-nuclear estrogen signaling R-HSA-9009391
Signal transduction by L1 R-HSA-445144
Toll-like Receptor Cascades R-HSA-168898
Cellular response to heat stress R-HSA-3371556
Regulation of PTEN gene transcription R-HSA-8943724
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Prolonged ERK activation events R-HSA-169893
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Transmission across Chemical Synapses R-HSA-112315
Parasite infection R-HSA-9664407
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Generic Transcription Pathway R-HSA-212436
Negative regulation of the PI3K/AKT network R-HSA-199418
Cellular responses to stress R-HSA-2262752
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Frs2-mediated activation R-HSA-170968
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Intrinsic Pathway for Apoptosis R-HSA-109606
Formation of apoptosome R-HSA-111458
ISG15 antiviral mechanism R-HSA-1169408
Negative regulation of FGFR1 signaling R-HSA-5654726
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Cytokine Signaling in Immune system R-HSA-1280215
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAP kinase activation R-HSA-450294
RNA Polymerase I Promoter Opening R-HSA-73728
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
NCAM signaling for neurite out-growth R-HSA-375165
Leishmania phagocytosis R-HSA-9664417
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Interferon Signaling R-HSA-913531
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR2 signaling R-HSA-5654727
RUNX2 regulates bone development R-HSA-8941326
Interleukin-17 signaling R-HSA-448424
Immune System R-HSA-168256
Signaling by Insulin receptor R-HSA-74752
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Insulin receptor signalling cascade R-HSA-74751
Signaling by NODAL R-HSA-1181150
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Negative regulation of MAPK pathway R-HSA-5675221
Signal Transduction R-HSA-162582
Regulation of the apoptosome activity R-HSA-9627069
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Post NMDA receptor activation events R-HSA-438064
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Apoptotic factor-mediated response R-HSA-111471
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signal attenuation R-HSA-74749
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Hemostasis R-HSA-109582
MAP2K and MAPK activation R-HSA-5674135
ERKs are inactivated R-HSA-202670
Growth hormone receptor signaling R-HSA-982772
L1CAM interactions R-HSA-373760
Signaling by Rho GTPases R-HSA-194315
ESR-mediated signaling R-HSA-8939211
FCERI mediated MAPK activation R-HSA-2871796
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Response of Mtb to phagocytosis R-HSA-9637690
Neuronal System R-HSA-112316
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Cell Cycle R-HSA-1640170
RHO GTPase Effectors R-HSA-195258
Signaling by Nuclear Receptors R-HSA-9006931
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Oxidative Stress Induced Senescence R-HSA-2559580
Apoptosis R-HSA-109581
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signalling to ERKs R-HSA-187687
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
GPCR downstream signalling R-HSA-388396
RNA Polymerase I Transcription R-HSA-73864
Signaling by FGFR2 R-HSA-5654738
PTEN Regulation R-HSA-6807070
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by RAS mutants R-HSA-6802949
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by FGFR R-HSA-190236
Cytochrome c-mediated apoptotic response R-HSA-111461
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by ALK in cancer R-HSA-9700206
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by RAF1 mutants R-HSA-9656223
Cellular Senescence R-HSA-2559583
Transcriptional Regulation by NPAS4 R-HSA-9634815
Negative feedback regulation of MAPK pathway R-HSA-5674499
Cellular responses to stimuli R-HSA-8953897
Signaling by FGFR1 R-HSA-5654736
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by TGFB family members R-HSA-9006936
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Gene expression (Transcription) R-HSA-74160
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Leishmania infection R-HSA-9658195
Signaling by GPCR R-HSA-372790
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Activin R-HSA-1502540
MyD88 cascade initiated on plasma membrane R-HSA-975871
Negative regulation of FGFR3 signaling R-HSA-5654732
MAPK3 (ERK1) activation R-HSA-110056

Expression Atlas ENSG00000102882
NCBI gene (formerly Entrezgene) 5595
GeneCards 6877
HGNC Symbol HGNC:6877
MIM gene 601795
UniProtKB Gene Name P27361
WikiGene 5595