Gene: SCN9A
Ensembl ID : ENSG00000169432
Description: sodium voltage-gated channel alpha subunit 9
Gene Synonyms: ETHA,NAV1.7,NE-NA,NENA,PN1
65 APIs:
109 Possible Orthologues:

Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Sensory Perception R-HSA-9709957
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
L1CAM interactions R-HSA-373760
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207
Sensory perception of taste R-HSA-9717189
Phase 0 - rapid depolarisation R-HSA-5576892
Interaction between L1 and Ankyrins R-HSA-445095
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Sensory perception of taste R-HSA-9717189
Muscle contraction R-HSA-397014
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207
Sensory Perception R-HSA-9709957
L1CAM interactions R-HSA-373760
Nervous system development R-HSA-9675108
Cardiac conduction R-HSA-5576891
Phase 0 - rapid depolarisation R-HSA-5576892
Developmental Biology R-HSA-1266738
Interaction between L1 and Ankyrins R-HSA-445095
Sensory perception of taste R-HSA-9717189
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Nervous system development R-HSA-9675108
L1CAM interactions R-HSA-373760
Sensory Perception R-HSA-9709957
Phase 0 - rapid depolarisation R-HSA-5576892
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207
Interaction between L1 and Ankyrins R-HSA-445095
Cardiac conduction R-HSA-5576891
Phase 0 - rapid depolarisation R-HSA-5576892
Muscle contraction R-HSA-397014
Axon guidance R-HSA-422475
L1CAM interactions R-HSA-373760
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207
Interaction between L1 and Ankyrins R-HSA-445095
Sensory Perception R-HSA-9709957
Sensory perception of taste R-HSA-9717189
L1CAM interactions R-HSA-373760
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207
Interaction between L1 and Ankyrins R-HSA-445095
Axon guidance R-HSA-422475
Phase 0 - rapid depolarisation R-HSA-5576892
Sensory perception of taste R-HSA-9717189
Sensory Perception R-HSA-9709957
Developmental Biology R-HSA-1266738
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
Muscle contraction R-HSA-397014
Nervous system development R-HSA-9675108
L1CAM interactions R-HSA-373760
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207
Interaction between L1 and Ankyrins R-HSA-445095
Sensory Perception R-HSA-9709957
Phase 0 - rapid depolarisation R-HSA-5576892
Developmental Biology R-HSA-1266738
Sensory perception of taste R-HSA-9717189
Cardiac conduction R-HSA-5576891
Developmental Biology R-HSA-1266738
L1CAM interactions R-HSA-373760
Interaction between L1 and Ankyrins R-HSA-445095
Nervous system development R-HSA-9675108
Sensory Perception R-HSA-9709957
Phase 0 - rapid depolarisation R-HSA-5576892
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207
Axon guidance R-HSA-422475
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Sensory perception of taste R-HSA-9717189

Expression Atlas ENSG00000169432
LRG display in Ensembl gene LRG_369
NCBI gene (formerly Entrezgene) 6335
GeneCards 10597
HGNC Symbol HGNC:10597
MIM gene 603415
MIM morbid 243000
UniProtKB Gene Name Q15858
WikiGene 6335
Gene: SEM1
Ensembl ID : ENSG00000127922
Description: SEM1 26S proteasome subunit
Gene Synonyms: C7ORF76,DSS1,ECD,FLJ42280,PSMD15,SHFD1,SHFDG1,SHFM1,SHSF1
5 APIs:
156 Possible Orthologues:

Synthesis of DNA R-HSA-69239
Degradation of AXIN R-HSA-4641257
Metabolism R-HSA-1430728
Signaling by NOTCH R-HSA-157118
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX3 R-HSA-8878159
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism R-HSA-1430728
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Post-translational protein modification R-HSA-597592
Programmed Cell Death R-HSA-5357801
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TCR signaling R-HSA-202403
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Mitotic Metaphase and Anaphase R-HSA-2555396
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH R-HSA-157118
Signaling by WNT R-HSA-195721
Metabolism of RNA R-HSA-8953854
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream TCR signaling R-HSA-202424
Homology Directed Repair R-HSA-5693538
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX3 expression and activity R-HSA-8941858
C-type lectin receptors (CLRs) R-HSA-5621481
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Degradation of GLI1 by the proteasome R-HSA-5610780
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of amino acids and derivatives R-HSA-71291
S Phase R-HSA-69242
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Hh mutants are degraded by ERAD R-HSA-5362768
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of expression of SLITs and ROBOs R-HSA-9010553
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle, Mitotic R-HSA-69278
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Asymmetric localization of PCP proteins R-HSA-4608870
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Neddylation R-HSA-8951664
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication R-HSA-69306
PTEN Regulation R-HSA-6807070
CLEC7A (Dectin-1) signaling R-HSA-5607764
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent DNA Damage Response R-HSA-69610
DNA Double-Strand Break Repair R-HSA-5693532
Developmental Biology R-HSA-1266738
Degradation of DVL R-HSA-4641258
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Assembly of the pre-replicative complex R-HSA-68867
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
UCH proteinases R-HSA-5689603
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Cellular responses to stimuli R-HSA-8953897
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G1 phase and G1/S transition R-HSA-453279
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Defective CFTR causes cystic fibrosis R-HSA-5678895
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
HDR through Homologous Recombination (HRR) R-HSA-5685942
Intracellular signaling by second messengers R-HSA-9006925
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transport of small molecules R-HSA-382551
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of beta-catenin by the destruction complex R-HSA-195253
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Interleukin-1 family signaling R-HSA-446652
Interleukin-1 signaling R-HSA-9020702
Hh mutants abrogate ligand secretion R-HSA-5387390
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Mitotic G2-G2/M phases R-HSA-453274
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle R-HSA-1640170
Degradation of AXIN R-HSA-4641257
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
PIP3 activates AKT signaling R-HSA-1257604
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Interleukins R-HSA-449147
Infectious disease R-HSA-5663205
Ub-specific processing proteases R-HSA-5689880
Nervous system development R-HSA-9675108
Nuclear events mediated by NFE2L2 R-HSA-9759194
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ABC-family proteins mediated transport R-HSA-382556
Regulation of Apoptosis R-HSA-169911
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disease R-HSA-1643685
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
M Phase R-HSA-68886
Negative regulation of NOTCH4 signaling R-HSA-9604323
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mitotic cell cycle R-HSA-453276
Adaptive Immune System R-HSA-1280218
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of polyamines R-HSA-351202
DNA Repair R-HSA-73894
ER-Phagosome pathway R-HSA-1236974
Stabilization of p53 R-HSA-69541
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
Hedgehog 'on' state R-HSA-5632684
MAPK6/MAPK4 signaling R-HSA-5687128
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
DNA Replication Pre-Initiation R-HSA-69002
Resolution of D-Loop Structures R-HSA-5693537
G2/M Checkpoints R-HSA-69481
MAPK family signaling cascades R-HSA-5683057
Signaling by Hedgehog R-HSA-5358351
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Generic Transcription Pathway R-HSA-212436
Cell Cycle Checkpoints R-HSA-69620
Disorders of transmembrane transporters R-HSA-5619115
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Signal Transduction R-HSA-162582
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular response to chemical stress R-HSA-9711123
Cyclin E associated events during G1/S transition R-HSA-69202
Orc1 removal from chromatin R-HSA-68949
HIV Infection R-HSA-162906
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of DNA repair R-HSA-9675135
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Anaphase R-HSA-68882
Cytokine Signaling in Immune system R-HSA-1280215
p53-Dependent G1 DNA Damage Response R-HSA-69563
Assembly of the pre-replicative complex R-HSA-68867
Disorders of transmembrane transporters R-HSA-5619115
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hh mutants abrogate ligand secretion R-HSA-5387390
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G2-G2/M phases R-HSA-453274
Cellular responses to stress R-HSA-2262752
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Hedgehog R-HSA-5358351
DNA Replication R-HSA-69306
S Phase R-HSA-69242
Regulation of RAS by GAPs R-HSA-5658442
Degradation of DVL R-HSA-4641258
Cell Cycle R-HSA-1640170
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Neddylation R-HSA-8951664
DNA Replication Pre-Initiation R-HSA-69002
p53-Independent DNA Damage Response R-HSA-69610
Programmed Cell Death R-HSA-5357801
Metabolism of polyamines R-HSA-351202
Generic Transcription Pathway R-HSA-212436
RAF/MAP kinase cascade R-HSA-5673001
PCP/CE pathway R-HSA-4086400
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Apoptosis R-HSA-109581
Signaling by the B Cell Receptor (BCR) R-HSA-983705
MAPK6/MAPK4 signaling R-HSA-5687128
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of beta-catenin by the destruction complex R-HSA-195253
HIV Infection R-HSA-162906
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signal Transduction R-HSA-162582
Homology Directed Repair R-HSA-5693538
Interleukin-1 family signaling R-HSA-446652
M Phase R-HSA-68886
Vpu mediated degradation of CD4 R-HSA-180534
Developmental Biology R-HSA-1266738
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
UCH proteinases R-HSA-5689603
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G2/M Transition R-HSA-69275
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Interleukin-1 signaling R-HSA-9020702
Degradation of GLI1 by the proteasome R-HSA-5610780
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular response to hypoxia R-HSA-1234174
Innate Immune System R-HSA-168249
Axon guidance R-HSA-422475
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TCR signaling R-HSA-202403
Cell Cycle, Mitotic R-HSA-69278
Metabolism of RNA R-HSA-8953854
Cellular response to chemical stress R-HSA-9711123
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
CLEC7A (Dectin-1) signaling R-HSA-5607764
Deubiquitination R-HSA-5688426
Orc1 removal from chromatin R-HSA-68949
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of mitotic cell cycle R-HSA-453276
Disease R-HSA-1643685
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Separation of Sister Chromatids R-HSA-2467813
G1/S DNA Damage Checkpoints R-HSA-69615
Nervous system development R-HSA-9675108
Cell Cycle Checkpoints R-HSA-69620
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
FCERI mediated NF-kB activation R-HSA-2871837
Stabilization of p53 R-HSA-69541
HDR through Homologous Recombination (HRR) R-HSA-5685942
TCF dependent signaling in response to WNT R-HSA-201681
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX2 R-HSA-8878166
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of DNA repair R-HSA-9675135
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Double-Strand Break Repair R-HSA-5693532
G1/S Transition R-HSA-69206
Hh mutants are degraded by ERAD R-HSA-5362768
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
DNA Repair R-HSA-73894
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Activation of NF-kappaB in B cells R-HSA-1169091
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Resolution of D-Loop Structures R-HSA-5693537
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism R-HSA-1430728
Regulation of PTEN stability and activity R-HSA-8948751
Nuclear events mediated by NFE2L2 R-HSA-9759194
RNA Polymerase II Transcription R-HSA-73857
Antigen processing-Cross presentation R-HSA-1236975
Mitotic G1 phase and G1/S transition R-HSA-453279
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Downstream TCR signaling R-HSA-202424
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
Gene expression (Transcription) R-HSA-74160
ABC-family proteins mediated transport R-HSA-382556
Synthesis of DNA R-HSA-69239
Metabolism of proteins R-HSA-392499
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'on' state R-HSA-5632684
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
ABC transporter disorders R-HSA-5619084
Cellular responses to stimuli R-HSA-8953897
Class I MHC mediated antigen processing & presentation R-HSA-983169
Transport of small molecules R-HSA-382551
PTEN Regulation R-HSA-6807070
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Immune System R-HSA-168256
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Infectious disease R-HSA-5663205
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
ER-Phagosome pathway R-HSA-1236974
Regulation of Apoptosis R-HSA-169911
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Switching of origins to a post-replicative state R-HSA-69052
Intracellular signaling by second messengers R-HSA-9006925
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Post-translational protein modification R-HSA-597592
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'off' state R-HSA-5610787
C-type lectin receptors (CLRs) R-HSA-5621481
Adaptive Immune System R-HSA-1280218
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic Anaphase R-HSA-68882
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Ub-specific processing proteases R-HSA-5689880
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Asymmetric localization of PCP proteins R-HSA-4608870
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Signaling by WNT R-HSA-195721
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transcriptional regulation by RUNX3 R-HSA-8878159
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Regulation of RUNX2 expression and activity R-HSA-8939902
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Orc1 removal from chromatin R-HSA-68949
Developmental Biology R-HSA-1266738
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G1/S Transition R-HSA-69206
Metabolism of amino acids and derivatives R-HSA-71291
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of Apoptosis R-HSA-169911
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by WNT R-HSA-195721
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Gene expression (Transcription) R-HSA-74160
Cellular response to hypoxia R-HSA-1234174
HDR through Homologous Recombination (HRR) R-HSA-5685942
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
PTEN Regulation R-HSA-6807070
Assembly of the pre-replicative complex R-HSA-68867
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Transition R-HSA-69275
Cyclin E associated events during G1/S transition R-HSA-69202
G2/M Checkpoints R-HSA-69481
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by NOTCH R-HSA-157118
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
HIV Infection R-HSA-162906
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of RNA R-HSA-8953854
TCR signaling R-HSA-202403
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
DNA Double-Strand Break Repair R-HSA-5693532
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Diseases of DNA repair R-HSA-9675135
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
Antigen processing-Cross presentation R-HSA-1236975
MAPK6/MAPK4 signaling R-HSA-5687128
Post-translational protein modification R-HSA-597592
Class I MHC mediated antigen processing & presentation R-HSA-983169
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 family signaling R-HSA-446652
Generic Transcription Pathway R-HSA-212436
Transport of small molecules R-HSA-382551
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Intracellular signaling by second messengers R-HSA-9006925
ER-Phagosome pathway R-HSA-1236974
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
CLEC7A (Dectin-1) signaling R-HSA-5607764
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Mitotic G1 phase and G1/S transition R-HSA-453279
Innate Immune System R-HSA-168249
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream TCR signaling R-HSA-202424
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC-family proteins mediated transport R-HSA-382556
Metabolism of polyamines R-HSA-351202
Adaptive Immune System R-HSA-1280218
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Negative regulation of NOTCH4 signaling R-HSA-9604323
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle, Mitotic R-HSA-69278
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stimuli R-HSA-8953897
Regulation of mitotic cell cycle R-HSA-453276
G1/S DNA Damage Checkpoints R-HSA-69615
Host Interactions of HIV factors R-HSA-162909
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
Deubiquitination R-HSA-5688426
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
DNA Replication Pre-Initiation R-HSA-69002
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of RAS by GAPs R-HSA-5658442
Signaling by ROBO receptors R-HSA-376176
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Vpu mediated degradation of CD4 R-HSA-180534
DNA Repair R-HSA-73894
Cellular response to chemical stress R-HSA-9711123
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Apoptosis R-HSA-109581
Signaling by Hedgehog R-HSA-5358351
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G2-G2/M phases R-HSA-453274
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX3 R-HSA-8878159
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
PCP/CE pathway R-HSA-4086400
Degradation of DVL R-HSA-4641258
Degradation of AXIN R-HSA-4641257
Asymmetric localization of PCP proteins R-HSA-4608870
Synthesis of DNA R-HSA-69239
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants are degraded by ERAD R-HSA-5362768
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
DNA Replication R-HSA-69306
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of GLI2 by the proteasome R-HSA-5610783
C-type lectin receptors (CLRs) R-HSA-5621481
Infectious disease R-HSA-5663205
Resolution of D-Loop Structures R-HSA-5693537
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX1 R-HSA-8878171
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants abrogate ligand secretion R-HSA-5387390
RNA Polymerase II Transcription R-HSA-73857
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Homology Directed Repair R-HSA-5693538
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Immune System R-HSA-168256
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hedgehog 'off' state R-HSA-5610787
Disorders of transmembrane transporters R-HSA-5619115
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by NOTCH4 R-HSA-9013694
M Phase R-HSA-68886
Cellular responses to stress R-HSA-2262752
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
Nervous system development R-HSA-9675108
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Separation of Sister Chromatids R-HSA-2467813
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'on' state R-HSA-5632684
S Phase R-HSA-69242
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vif-mediated degradation of APOBEC3G R-HSA-180585
G2/M Checkpoints R-HSA-69481
PCP/CE pathway R-HSA-4086400
p53-Independent DNA Damage Response R-HSA-69610
Metabolism R-HSA-1430728
Diseases of DNA repair R-HSA-9675135
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Interleukin-1 signaling R-HSA-9020702
DNA Replication Pre-Initiation R-HSA-69002
MAPK1/MAPK3 signaling R-HSA-5684996
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Gene expression (Transcription) R-HSA-74160
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Interleukin-1 family signaling R-HSA-446652
DNA Double-Strand Break Repair R-HSA-5693532
Signaling by Interleukins R-HSA-449147
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
Adaptive Immune System R-HSA-1280218
Mitotic Anaphase R-HSA-68882
Signaling by Hedgehog R-HSA-5358351
Cellular response to chemical stress R-HSA-9711123
Signal Transduction R-HSA-162582
Post-translational protein modification R-HSA-597592
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Infectious disease R-HSA-5663205
Regulation of Apoptosis R-HSA-169911
FCERI mediated NF-kB activation R-HSA-2871837
Hedgehog 'on' state R-HSA-5632684
Hedgehog 'off' state R-HSA-5610787
HIV Infection R-HSA-162906
p53-Dependent G1 DNA Damage Response R-HSA-69563
Disorders of transmembrane transporters R-HSA-5619115
Neddylation R-HSA-8951664
Regulation of RUNX3 expression and activity R-HSA-8941858
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic G1 phase and G1/S transition R-HSA-453279
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Transcriptional regulation by RUNX2 R-HSA-8878166
PTEN Regulation R-HSA-6807070
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Separation of Sister Chromatids R-HSA-2467813
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
KEAP1-NFE2L2 pathway R-HSA-9755511
Class I MHC mediated antigen processing & presentation R-HSA-983169
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S DNA Damage Checkpoints R-HSA-69615
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Synthesis of DNA R-HSA-69239
UCH proteinases R-HSA-5689603
TCF dependent signaling in response to WNT R-HSA-201681
Downstream TCR signaling R-HSA-202424
Apoptosis R-HSA-109581
Disease R-HSA-1643685
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Innate Immune System R-HSA-168249
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Transport of small molecules R-HSA-382551
Degradation of DVL R-HSA-4641258
Nuclear events mediated by NFE2L2 R-HSA-9759194
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Mitotic G2-G2/M phases R-HSA-453274
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
Assembly of the pre-replicative complex R-HSA-68867
DNA Replication R-HSA-69306
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
RNA Polymerase II Transcription R-HSA-73857
Resolution of D-Loop Structures R-HSA-5693537
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of beta-catenin by the destruction complex R-HSA-195253
Generic Transcription Pathway R-HSA-212436
HDR through Homologous Recombination (HRR) R-HSA-5685942
G1/S Transition R-HSA-69206
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Metabolism of amino acids and derivatives R-HSA-71291
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Homology Directed Repair R-HSA-5693538
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ABC-family proteins mediated transport R-HSA-382556
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of proteins R-HSA-392499
Programmed Cell Death R-HSA-5357801
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle, Mitotic R-HSA-69278
Regulation of mitotic cell cycle R-HSA-453276
ABC transporter disorders R-HSA-5619084
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Hedgehog ligand biogenesis R-HSA-5358346
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stimuli R-HSA-8953897
C-type lectin receptors (CLRs) R-HSA-5621481
Cytokine Signaling in Immune system R-HSA-1280215
ER-Phagosome pathway R-HSA-1236974
MAPK family signaling cascades R-HSA-5683057
Negative regulation of NOTCH4 signaling R-HSA-9604323
Deubiquitination R-HSA-5688426
Stabilization of p53 R-HSA-69541
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
PIP3 activates AKT signaling R-HSA-1257604
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Intracellular signaling by second messengers R-HSA-9006925
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by NOTCH4 R-HSA-9013694
Signaling by ROBO receptors R-HSA-376176
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
M Phase R-HSA-68886
Cell Cycle Checkpoints R-HSA-69620
Regulation of RUNX2 expression and activity R-HSA-8939902
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of RNA R-HSA-8953854
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX3 R-HSA-8878159
Immune System R-HSA-168256
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of AXIN R-HSA-4641257
S Phase R-HSA-69242
Ub-specific processing proteases R-HSA-5689880
DNA Repair R-HSA-73894
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Signaling by WNT R-HSA-195721
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
RAF/MAP kinase cascade R-HSA-5673001
Switching of origins to a post-replicative state R-HSA-69052
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
G2/M Transition R-HSA-69275
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PTEN Regulation R-HSA-6807070
Apoptosis R-HSA-109581
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Separation of Sister Chromatids R-HSA-2467813
Activation of NF-kappaB in B cells R-HSA-1169091
Innate Immune System R-HSA-168249
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Interleukin-1 signaling R-HSA-9020702
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
HIV Infection R-HSA-162906
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transport of small molecules R-HSA-382551
Cellular response to hypoxia R-HSA-1234174
DNA Replication Pre-Initiation R-HSA-69002
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Host Interactions of HIV factors R-HSA-162909
Stabilization of p53 R-HSA-69541
Cellular response to chemical stress R-HSA-9711123
Metabolism of RNA R-HSA-8953854
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Deubiquitination R-HSA-5688426
Infectious disease R-HSA-5663205
FCERI mediated NF-kB activation R-HSA-2871837
KEAP1-NFE2L2 pathway R-HSA-9755511
Ub-specific processing proteases R-HSA-5689880
DNA Double-Strand Break Repair R-HSA-5693532
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
Cellular responses to stress R-HSA-2262752
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Post-translational protein modification R-HSA-597592
CLEC7A (Dectin-1) signaling R-HSA-5607764
Orc1 removal from chromatin R-HSA-68949
Homology Directed Repair R-HSA-5693538
PCP/CE pathway R-HSA-4086400
Vpu mediated degradation of CD4 R-HSA-180534
Class I MHC mediated antigen processing & presentation R-HSA-983169
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Immune System R-HSA-168256
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of DVL R-HSA-4641258
Degradation of AXIN R-HSA-4641257
Downstream TCR signaling R-HSA-202424
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Developmental Biology R-HSA-1266738
Signaling by WNT R-HSA-195721
M Phase R-HSA-68886
Mitotic G2-G2/M phases R-HSA-453274
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Generic Transcription Pathway R-HSA-212436
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
Hh mutants are degraded by ERAD R-HSA-5362768
Hedgehog 'on' state R-HSA-5632684
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
Resolution of D-Loop Structures R-HSA-5693537
Axon guidance R-HSA-422475
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle, Mitotic R-HSA-69278
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK family signaling cascades R-HSA-5683057
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Intracellular signaling by second messengers R-HSA-9006925
G2/M Checkpoints R-HSA-69481
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic Anaphase R-HSA-68882
p53-Independent DNA Damage Response R-HSA-69610
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Programmed Cell Death R-HSA-5357801
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Transcriptional regulation by RUNX3 R-HSA-8878159
DNA Repair R-HSA-73894
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of RUNX3 expression and activity R-HSA-8941858
Signal Transduction R-HSA-162582
G1/S Transition R-HSA-69206
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Switching of origins to a post-replicative state R-HSA-69052
ER-Phagosome pathway R-HSA-1236974
Antigen processing-Cross presentation R-HSA-1236975
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
NIK-->noncanonical NF-kB signaling R-HSA-5676590
PIP3 activates AKT signaling R-HSA-1257604
Regulation of Apoptosis R-HSA-169911
Metabolism of proteins R-HSA-392499
Signaling by Hedgehog R-HSA-5358351
S Phase R-HSA-69242
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Metabolism of polyamines R-HSA-351202
Diseases of DNA repair R-HSA-9675135
Cyclin E associated events during G1/S transition R-HSA-69202
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
DNA Replication R-HSA-69306
MAPK6/MAPK4 signaling R-HSA-5687128
MAPK1/MAPK3 signaling R-HSA-5684996
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Neddylation R-HSA-8951664
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
TCR signaling R-HSA-202403
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mitotic cell cycle R-HSA-453276
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by ROBO receptors R-HSA-376176
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RAF/MAP kinase cascade R-HSA-5673001
Regulation of RAS by GAPs R-HSA-5658442
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
Hedgehog 'off' state R-HSA-5610787
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Negative regulation of NOTCH4 signaling R-HSA-9604323
HDR through Homologous Recombination (HRR) R-HSA-5685942
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
Cell Cycle R-HSA-1640170
ABC-family proteins mediated transport R-HSA-382556
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Adaptive Immune System R-HSA-1280218
Hedgehog ligand biogenesis R-HSA-5358346
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic Metaphase and Anaphase R-HSA-2555396
G2/M Checkpoints R-HSA-69481
PTEN Regulation R-HSA-6807070
Mitotic G2-G2/M phases R-HSA-453274
Separation of Sister Chromatids R-HSA-2467813
Hedgehog 'off' state R-HSA-5610787
Regulation of PTEN stability and activity R-HSA-8948751
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Innate Immune System R-HSA-168249
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Degradation of AXIN R-HSA-4641257
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by NOTCH4 R-HSA-9013694
MAPK family signaling cascades R-HSA-5683057
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S Transition R-HSA-69206
Nuclear events mediated by NFE2L2 R-HSA-9759194
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ub-specific processing proteases R-HSA-5689880
PIP3 activates AKT signaling R-HSA-1257604
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stress R-HSA-2262752
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 signaling R-HSA-9020702
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Transport of small molecules R-HSA-382551
Regulation of Apoptosis R-HSA-169911
Signaling by Interleukins R-HSA-449147
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of beta-catenin by the destruction complex R-HSA-195253
Negative regulation of NOTCH4 signaling R-HSA-9604323
MAPK6/MAPK4 signaling R-HSA-5687128
Axon guidance R-HSA-422475
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Impaired BRCA2 binding to RAD51 R-HSA-9709570
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI1 by the proteasome R-HSA-5610780
Nervous system development R-HSA-9675108
Cellular response to chemical stress R-HSA-9711123
S Phase R-HSA-69242
Hedgehog 'on' state R-HSA-5632684
Class I MHC mediated antigen processing & presentation R-HSA-983169
Signaling by NOTCH R-HSA-157118
ABC transporter disorders R-HSA-5619084
Synthesis of DNA R-HSA-69239
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Stabilization of p53 R-HSA-69541
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Metabolism of RNA R-HSA-8953854
Downstream TCR signaling R-HSA-202424
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX3 R-HSA-8878159
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RAF/MAP kinase cascade R-HSA-5673001
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by ROBO receptors R-HSA-376176
Programmed Cell Death R-HSA-5357801
Regulation of RAS by GAPs R-HSA-5658442
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK1/MAPK3 signaling R-HSA-5684996
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to hypoxia R-HSA-1234174
HIV Infection R-HSA-162906
CLEC7A (Dectin-1) signaling R-HSA-5607764
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
DNA Double-Strand Break Repair R-HSA-5693532
Deubiquitination R-HSA-5688426
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Defective CFTR causes cystic fibrosis R-HSA-5678895
Adaptive Immune System R-HSA-1280218
Resolution of D-Loop Structures R-HSA-5693537
Regulation of mitotic cell cycle R-HSA-453276
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Degradation of DVL R-HSA-4641258
Disorders of transmembrane transporters R-HSA-5619115
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX2 R-HSA-8878166
Generic Transcription Pathway R-HSA-212436
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Asymmetric localization of PCP proteins R-HSA-4608870
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
DNA Replication R-HSA-69306
Orc1 removal from chromatin R-HSA-68949
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
FCERI mediated NF-kB activation R-HSA-2871837
HDR through Homologous Recombination (HRR) R-HSA-5685942
TCF dependent signaling in response to WNT R-HSA-201681
Vif-mediated degradation of APOBEC3G R-HSA-180585
DNA Replication Pre-Initiation R-HSA-69002
Host Interactions of HIV factors R-HSA-162909
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
PCP/CE pathway R-HSA-4086400
Hh mutants abrogate ligand secretion R-HSA-5387390
M Phase R-HSA-68886
Diseases of DNA repair R-HSA-9675135
Regulation of RUNX2 expression and activity R-HSA-8939902
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of polyamines R-HSA-351202
Cytokine Signaling in Immune system R-HSA-1280215
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of amino acids and derivatives R-HSA-71291
Hh mutants are degraded by ERAD R-HSA-5362768
Apoptosis R-HSA-109581
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle Checkpoints R-HSA-69620
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
C-type lectin receptors (CLRs) R-HSA-5621481
Neddylation R-HSA-8951664
Cell Cycle, Mitotic R-HSA-69278
TCR signaling R-HSA-202403
Infectious disease R-HSA-5663205
NIK-->noncanonical NF-kB signaling R-HSA-5676590
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism R-HSA-1430728
Mitotic Anaphase R-HSA-68882
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
ER-Phagosome pathway R-HSA-1236974
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX1 R-HSA-8878171
DNA Repair R-HSA-73894
Metabolism of proteins R-HSA-392499
Signaling by WNT R-HSA-195721
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Hedgehog R-HSA-5358351
Post-translational protein modification R-HSA-597592
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RNA Polymerase II Transcription R-HSA-73857
Assembly of the pre-replicative complex R-HSA-68867
Switching of origins to a post-replicative state R-HSA-69052
Homology Directed Repair R-HSA-5693538
Cyclin E associated events during G1/S transition R-HSA-69202
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Disease R-HSA-1643685
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle R-HSA-1640170
Nervous system development R-HSA-9675108
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Diseases of DNA repair R-HSA-9675135
Separation of Sister Chromatids R-HSA-2467813
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G2/M Checkpoints R-HSA-69481
Impaired BRCA2 binding to RAD51 R-HSA-9709570
ER-Phagosome pathway R-HSA-1236974
Degradation of beta-catenin by the destruction complex R-HSA-195253
Disorders of transmembrane transporters R-HSA-5619115
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Deubiquitination R-HSA-5688426
HDR through Homologous Recombination (HRR) R-HSA-5685942
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Cell Cycle Checkpoints R-HSA-69620
Signaling by WNT R-HSA-195721
M Phase R-HSA-68886
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic Metaphase and Anaphase R-HSA-2555396
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Intracellular signaling by second messengers R-HSA-9006925
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Host Interactions of HIV factors R-HSA-162909
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of proteins R-HSA-392499
Resolution of D-Loop Structures R-HSA-5693537
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G2-G2/M phases R-HSA-453274
Asymmetric localization of PCP proteins R-HSA-4608870
PTEN Regulation R-HSA-6807070
Generic Transcription Pathway R-HSA-212436
Degradation of GLI1 by the proteasome R-HSA-5610780
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vpu mediated degradation of CD4 R-HSA-180534
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of Apoptosis R-HSA-169911
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Downstream TCR signaling R-HSA-202424
Cellular response to hypoxia R-HSA-1234174
Cell Cycle, Mitotic R-HSA-69278
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to chemical stress R-HSA-9711123
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Anaphase R-HSA-68882
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
UCH proteinases R-HSA-5689603
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog 'off' state R-HSA-5610787
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of mitotic cell cycle R-HSA-453276
DNA Replication R-HSA-69306
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of amino acids and derivatives R-HSA-71291
ABC transporter disorders R-HSA-5619084
G2/M Transition R-HSA-69275
Metabolism of polyamines R-HSA-351202
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of DVL R-HSA-4641258
p53-Independent DNA Damage Response R-HSA-69610
Programmed Cell Death R-HSA-5357801
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stress R-HSA-2262752
NIK-->noncanonical NF-kB signaling R-HSA-5676590
S Phase R-HSA-69242
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cytokine Signaling in Immune system R-HSA-1280215
ABC-family proteins mediated transport R-HSA-382556
Metabolism R-HSA-1430728
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Signaling by Hedgehog R-HSA-5358351
Innate Immune System R-HSA-168249
Gene expression (Transcription) R-HSA-74160
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Assembly of the pre-replicative complex R-HSA-68867
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
HIV Infection R-HSA-162906
Degradation of AXIN R-HSA-4641257
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Repair R-HSA-73894
PCP/CE pathway R-HSA-4086400
Cellular responses to stimuli R-HSA-8953897
Class I MHC mediated antigen processing & presentation R-HSA-983169
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX3 expression and activity R-HSA-8941858
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Interleukins R-HSA-449147
Homology Directed Repair R-HSA-5693538
Disease R-HSA-1643685
TCR signaling R-HSA-202403
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
DNA Double-Strand Break Repair R-HSA-5693532
Hh mutants abrogate ligand secretion R-HSA-5387390
Transcriptional regulation by RUNX1 R-HSA-8878171
Transcriptional regulation by RUNX2 R-HSA-8878166
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Orc1 removal from chromatin R-HSA-68949
Adaptive Immune System R-HSA-1280218
Negative regulation of NOTCH4 signaling R-HSA-9604323
PIP3 activates AKT signaling R-HSA-1257604
Stabilization of p53 R-HSA-69541
Metabolism of RNA R-HSA-8953854
Apoptosis R-HSA-109581
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Transport of small molecules R-HSA-382551
Post-translational protein modification R-HSA-597592
DNA Replication Pre-Initiation R-HSA-69002
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Neddylation R-HSA-8951664
FCERI mediated NF-kB activation R-HSA-2871837
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Interleukin-1 signaling R-HSA-9020702
G1/S DNA Damage Checkpoints R-HSA-69615
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hh mutants are degraded by ERAD R-HSA-5362768
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by NOTCH4 R-HSA-9013694
Nuclear events mediated by NFE2L2 R-HSA-9759194
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of polyamines R-HSA-351202
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle R-HSA-1640170
Vif-mediated degradation of APOBEC3G R-HSA-180585
Post-translational protein modification R-HSA-597592
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Host Interactions of HIV factors R-HSA-162909
Cell Cycle Checkpoints R-HSA-69620
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transcriptional regulation by RUNX1 R-HSA-8878171
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transport of small molecules R-HSA-382551
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of proteins R-HSA-392499
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX3 R-HSA-8878159
Generic Transcription Pathway R-HSA-212436
PCP/CE pathway R-HSA-4086400
Cyclin E associated events during G1/S transition R-HSA-69202
Defective CFTR causes cystic fibrosis R-HSA-5678895
Apoptosis R-HSA-109581
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Resolution of D-Loop Structures R-HSA-5693537
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Orc1 removal from chromatin R-HSA-68949
Regulation of mitotic cell cycle R-HSA-453276
Innate Immune System R-HSA-168249
MAPK6/MAPK4 signaling R-HSA-5687128
Negative regulation of NOTCH4 signaling R-HSA-9604323
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Assembly of the pre-replicative complex R-HSA-68867
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular response to chemical stress R-HSA-9711123
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of DVL R-HSA-4641258
Antigen processing-Cross presentation R-HSA-1236975
HDR through Homologous Recombination (HRR) R-HSA-5685942
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by Interleukins R-HSA-449147
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
PTEN Regulation R-HSA-6807070
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
UCH proteinases R-HSA-5689603
G1/S Transition R-HSA-69206
Regulation of Apoptosis R-HSA-169911
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
DNA Replication R-HSA-69306
RNA Polymerase II Transcription R-HSA-73857
G1/S DNA Damage Checkpoints R-HSA-69615
Deubiquitination R-HSA-5688426
Intracellular signaling by second messengers R-HSA-9006925
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of PTEN stability and activity R-HSA-8948751
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Regulation of RUNX2 expression and activity R-HSA-8939902
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cellular responses to stress R-HSA-2262752
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Immune System R-HSA-168256
HIV Infection R-HSA-162906
Cell Cycle, Mitotic R-HSA-69278
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
DNA Double-Strand Break Repair R-HSA-5693532
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Interleukin-1 signaling R-HSA-9020702
MAPK family signaling cascades R-HSA-5683057
Adaptive Immune System R-HSA-1280218
Mitotic G1 phase and G1/S transition R-HSA-453279
Ub-specific processing proteases R-HSA-5689880
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RUNX3 expression and activity R-HSA-8941858
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
Mitotic Anaphase R-HSA-68882
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
Beta-catenin independent WNT signaling R-HSA-3858494
DNA Replication Pre-Initiation R-HSA-69002
Diseases of DNA repair R-HSA-9675135
Signaling by ROBO receptors R-HSA-376176
Cellular response to hypoxia R-HSA-1234174
Vpu mediated degradation of CD4 R-HSA-180534
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Homology Directed Repair R-HSA-5693538
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
FCERI mediated NF-kB activation R-HSA-2871837
ER-Phagosome pathway R-HSA-1236974
Degradation of AXIN R-HSA-4641257
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
Mitotic Metaphase and Anaphase R-HSA-2555396
S Phase R-HSA-69242
Class I MHC mediated antigen processing & presentation R-HSA-983169
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
DNA Repair R-HSA-73894
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by NOTCH4 R-HSA-9013694
Hedgehog 'off' state R-HSA-5610787
Downstream TCR signaling R-HSA-202424
Gene expression (Transcription) R-HSA-74160
ABC-family proteins mediated transport R-HSA-382556
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Nervous system development R-HSA-9675108
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CLEC7A (Dectin-1) signaling R-HSA-5607764
Stabilization of p53 R-HSA-69541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G2-G2/M phases R-HSA-453274
Signaling by WNT R-HSA-195721
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 family signaling R-HSA-446652
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism R-HSA-1430728
M Phase R-HSA-68886
G2/M Transition R-HSA-69275
Signaling by Hedgehog R-HSA-5358351
Axon guidance R-HSA-422475
Synthesis of DNA R-HSA-69239
ABC transporter disorders R-HSA-5619084
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of RNA R-HSA-8953854
Switching of origins to a post-replicative state R-HSA-69052
Signal Transduction R-HSA-162582
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI2 by the proteasome R-HSA-5610783
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Programmed Cell Death R-HSA-5357801
DNA Repair R-HSA-73894
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Apoptosis R-HSA-109581
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Post-translational protein modification R-HSA-597592
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of PTEN stability and activity R-HSA-8948751
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular responses to stimuli R-HSA-8953897
Hh mutants abrogate ligand secretion R-HSA-5387390
Interleukin-1 signaling R-HSA-9020702
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
M Phase R-HSA-68886
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RAS by GAPs R-HSA-5658442
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Deubiquitination R-HSA-5688426
ER-Phagosome pathway R-HSA-1236974
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vpu mediated degradation of CD4 R-HSA-180534
Cellular response to hypoxia R-HSA-1234174
MAPK1/MAPK3 signaling R-HSA-5684996
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Signaling by Interleukins R-HSA-449147
Degradation of AXIN R-HSA-4641257
Axon guidance R-HSA-422475
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Regulation of RUNX2 expression and activity R-HSA-8939902
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell Cycle R-HSA-1640170
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX1 R-HSA-8878171
Transport of small molecules R-HSA-382551
Mitotic G2-G2/M phases R-HSA-453274
Diseases of DNA repair R-HSA-9675135
Infectious disease R-HSA-5663205
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Transcriptional regulation by RUNX3 R-HSA-8878159
Developmental Biology R-HSA-1266738
Cellular response to chemical stress R-HSA-9711123
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disorders of transmembrane transporters R-HSA-5619115
C-type lectin receptors (CLRs) R-HSA-5621481
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
TCR signaling R-HSA-202403
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Nuclear events mediated by NFE2L2 R-HSA-9759194
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
Switching of origins to a post-replicative state R-HSA-69052
S Phase R-HSA-69242
Metabolism of amino acids and derivatives R-HSA-71291
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog ligand biogenesis R-HSA-5358346
DNA Double-Strand Break Repair R-HSA-5693532
DNA Replication Pre-Initiation R-HSA-69002
NIK-->noncanonical NF-kB signaling R-HSA-5676590
HIV Infection R-HSA-162906
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Intracellular signaling by second messengers R-HSA-9006925
Downstream TCR signaling R-HSA-202424
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
Stabilization of p53 R-HSA-69541
p53-Independent DNA Damage Response R-HSA-69610
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
PTEN Regulation R-HSA-6807070
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Checkpoints R-HSA-69481
G2/M Transition R-HSA-69275
Mitotic G1 phase and G1/S transition R-HSA-453279
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
Assembly of the pre-replicative complex R-HSA-68867
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hh mutants are degraded by ERAD R-HSA-5362768
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Neddylation R-HSA-8951664
Degradation of DVL R-HSA-4641258
Host Interactions of HIV factors R-HSA-162909
Homology Directed Repair R-HSA-5693538
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Disease R-HSA-1643685
Interleukin-1 family signaling R-HSA-446652
Signaling by Hedgehog R-HSA-5358351
G1/S Transition R-HSA-69206
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Metabolism of proteins R-HSA-392499
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX3 expression and activity R-HSA-8941858
PCP/CE pathway R-HSA-4086400
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Adaptive Immune System R-HSA-1280218
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cyclin E associated events during G1/S transition R-HSA-69202
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
UCH proteinases R-HSA-5689603
Resolution of D-Loop Structures R-HSA-5693537
Signaling by ROBO receptors R-HSA-376176
Cell Cycle Checkpoints R-HSA-69620
Signaling by WNT R-HSA-195721
Cell Cycle, Mitotic R-HSA-69278
HDR through Homologous Recombination (HRR) R-HSA-5685942
Regulation of Apoptosis R-HSA-169911
Gene expression (Transcription) R-HSA-74160
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Asymmetric localization of PCP proteins R-HSA-4608870
KEAP1-NFE2L2 pathway R-HSA-9755511
Separation of Sister Chromatids R-HSA-2467813
Immune System R-HSA-168256
Metabolism of polyamines R-HSA-351202
ABC-family proteins mediated transport R-HSA-382556
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Beta-catenin independent WNT signaling R-HSA-3858494
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
FCERI mediated NF-kB activation R-HSA-2871837
Nervous system development R-HSA-9675108
Vif-mediated degradation of APOBEC3G R-HSA-180585
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Synthesis of DNA R-HSA-69239
PIP3 activates AKT signaling R-HSA-1257604
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
ABC transporter disorders R-HSA-5619084
RNA Polymerase II Transcription R-HSA-73857
Mitotic Anaphase R-HSA-68882
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by Interleukins R-HSA-449147
Regulation of RAS by GAPs R-HSA-5658442
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Metabolism of amino acids and derivatives R-HSA-71291
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Regulation of mitotic cell cycle R-HSA-453276
Disease R-HSA-1643685
Signaling by NOTCH R-HSA-157118
Cellular response to hypoxia R-HSA-1234174
DNA Replication Pre-Initiation R-HSA-69002
G1/S DNA Damage Checkpoints R-HSA-69615
Adaptive Immune System R-HSA-1280218
Generic Transcription Pathway R-HSA-212436
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Separation of Sister Chromatids R-HSA-2467813
RNA Polymerase II Transcription R-HSA-73857
Homology Directed Repair R-HSA-5693538
G2/M Transition R-HSA-69275
Vif-mediated degradation of APOBEC3G R-HSA-180585
Antigen processing-Cross presentation R-HSA-1236975
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 signaling R-HSA-9020702
DNA Double-Strand Break Repair R-HSA-5693532
Neddylation R-HSA-8951664
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Cellular responses to stimuli R-HSA-8953897
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Repair R-HSA-73894
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Cell Cycle Checkpoints R-HSA-69620
Ub-specific processing proteases R-HSA-5689880
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Gene expression (Transcription) R-HSA-74160
Synthesis of DNA R-HSA-69239
Degradation of GLI1 by the proteasome R-HSA-5610780
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ABC-family proteins mediated transport R-HSA-382556
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of RNA R-HSA-8953854
Resolution of D-Loop Structures R-HSA-5693537
Signaling by NOTCH4 R-HSA-9013694
Regulation of PTEN stability and activity R-HSA-8948751
MAPK family signaling cascades R-HSA-5683057
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S Transition R-HSA-69206
Hh mutants abrogate ligand secretion R-HSA-5387390
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Switching of origins to a post-replicative state R-HSA-69052
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream TCR signaling R-HSA-202424
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Transport of small molecules R-HSA-382551
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Host Interactions of HIV factors R-HSA-162909
Mitotic G2-G2/M phases R-HSA-453274
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX2 R-HSA-8878166
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
ABC transporter disorders R-HSA-5619084
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Cytokine Signaling in Immune system R-HSA-1280215
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism R-HSA-1430728
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Diseases of DNA repair R-HSA-9675135
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
S Phase R-HSA-69242
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Mitotic G1 phase and G1/S transition R-HSA-453279
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cell Cycle, Mitotic R-HSA-69278
Assembly of the pre-replicative complex R-HSA-68867
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disorders of transmembrane transporters R-HSA-5619115
Apoptosis R-HSA-109581
Degradation of DVL R-HSA-4641258
Orc1 removal from chromatin R-HSA-68949
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog ligand biogenesis R-HSA-5358346
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of proteins R-HSA-392499
Cyclin E associated events during G1/S transition R-HSA-69202
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular responses to stress R-HSA-2262752
Signaling by Hedgehog R-HSA-5358351
Mitotic Metaphase and Anaphase R-HSA-2555396
Programmed Cell Death R-HSA-5357801
Axon guidance R-HSA-422475
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Post-translational protein modification R-HSA-597592
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by the B Cell Receptor (BCR) R-HSA-983705
M Phase R-HSA-68886
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
CLEC7A (Dectin-1) signaling R-HSA-5607764
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
UCH proteinases R-HSA-5689603
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of AXIN R-HSA-4641257
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX1 R-HSA-8878171
HIV Infection R-HSA-162906
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
HDR through Homologous Recombination (HRR) R-HSA-5685942
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
KEAP1-NFE2L2 pathway R-HSA-9755511
PCP/CE pathway R-HSA-4086400
Stabilization of p53 R-HSA-69541
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX3 R-HSA-8878159
Developmental Biology R-HSA-1266738
Hedgehog 'off' state R-HSA-5610787
DNA Replication R-HSA-69306
Hh mutants are degraded by ERAD R-HSA-5362768
Signal Transduction R-HSA-162582
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
ER-Phagosome pathway R-HSA-1236974
Signaling by ROBO receptors R-HSA-376176
Negative regulation of NOTCH4 signaling R-HSA-9604323
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
TCF dependent signaling in response to WNT R-HSA-201681
Vpu mediated degradation of CD4 R-HSA-180534
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle R-HSA-1640170
Nervous system development R-HSA-9675108
Infectious disease R-HSA-5663205
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652

Expression Atlas ENSG00000127922
NCBI gene (formerly Entrezgene) 7979
GeneCards 10845
HGNC Symbol HGNC:10845
MIM gene 601285
UniProtKB Gene Name Q6ZVN7
WikiGene 7979
Gene: ATP1B2
Ensembl ID : ENSG00000129244
Description: ATPase Na+/K+ transporting subunit beta 2
Gene Synonyms: AMOG
6 APIs:
269 Possible Orthologues:

Muscle contraction R-HSA-397014
SARS-CoV Infections R-HSA-9679506
Potential therapeutics for SARS R-HSA-9679191
Transport of small molecules R-HSA-382551
Basigin interactions R-HSA-210991
Infectious disease R-HSA-5663205
Ion homeostasis R-HSA-5578775
Hemostasis R-HSA-109582
Cell surface interactions at the vascular wall R-HSA-202733
Disease R-HSA-1643685
Cardiac conduction R-HSA-5576891
Ion transport by P-type ATPases R-HSA-936837
Ion channel transport R-HSA-983712
SARS-CoV Infections R-HSA-9679506
Ion channel transport R-HSA-983712
Basigin interactions R-HSA-210991
Disease R-HSA-1643685
Hemostasis R-HSA-109582
Potential therapeutics for SARS R-HSA-9679191
Ion transport by P-type ATPases R-HSA-936837
Muscle contraction R-HSA-397014
Ion homeostasis R-HSA-5578775
Cardiac conduction R-HSA-5576891
Transport of small molecules R-HSA-382551
Infectious disease R-HSA-5663205
Cell surface interactions at the vascular wall R-HSA-202733
Disease R-HSA-1643685
Hemostasis R-HSA-109582
Ion channel transport R-HSA-983712
Basigin interactions R-HSA-210991
SARS-CoV Infections R-HSA-9679506
Infectious disease R-HSA-5663205
Ion transport by P-type ATPases R-HSA-936837
Ion homeostasis R-HSA-5578775
Cardiac conduction R-HSA-5576891
Potential therapeutics for SARS R-HSA-9679191
Transport of small molecules R-HSA-382551
Muscle contraction R-HSA-397014
Cell surface interactions at the vascular wall R-HSA-202733
Muscle contraction R-HSA-397014
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
SARS-CoV Infections R-HSA-9679506
Potential therapeutics for SARS R-HSA-9679191
Transport of small molecules R-HSA-382551
Basigin interactions R-HSA-210991
Ion channel transport R-HSA-983712
Ion homeostasis R-HSA-5578775
Hemostasis R-HSA-109582
Ion transport by P-type ATPases R-HSA-936837
Cell surface interactions at the vascular wall R-HSA-202733
Cardiac conduction R-HSA-5576891
Ion transport by P-type ATPases R-HSA-936837
Hemostasis R-HSA-109582
Ion channel transport R-HSA-983712
Transport of small molecules R-HSA-382551
Cell surface interactions at the vascular wall R-HSA-202733
Basigin interactions R-HSA-210991
Cardiac conduction R-HSA-5576891
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
Ion homeostasis R-HSA-5578775
Potential therapeutics for SARS R-HSA-9679191
Muscle contraction R-HSA-397014
Infectious disease R-HSA-5663205
Basigin interactions R-HSA-210991
Transport of small molecules R-HSA-382551
Ion channel transport R-HSA-983712
Ion homeostasis R-HSA-5578775
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Hemostasis R-HSA-109582
SARS-CoV Infections R-HSA-9679506
Cardiac conduction R-HSA-5576891
Cell surface interactions at the vascular wall R-HSA-202733
Ion transport by P-type ATPases R-HSA-936837
Hemostasis R-HSA-109582
Disease R-HSA-1643685
Muscle contraction R-HSA-397014
Basigin interactions R-HSA-210991
Potential therapeutics for SARS R-HSA-9679191
Transport of small molecules R-HSA-382551
Cell surface interactions at the vascular wall R-HSA-202733
Ion transport by P-type ATPases R-HSA-936837
Ion homeostasis R-HSA-5578775
Infectious disease R-HSA-5663205
Ion channel transport R-HSA-983712
Cardiac conduction R-HSA-5576891
SARS-CoV Infections R-HSA-9679506
Ion transport by P-type ATPases R-HSA-936837
Infectious disease R-HSA-5663205
Transport of small molecules R-HSA-382551
Cell surface interactions at the vascular wall R-HSA-202733
Disease R-HSA-1643685
Potential therapeutics for SARS R-HSA-9679191
Ion channel transport R-HSA-983712
Cardiac conduction R-HSA-5576891
Ion homeostasis R-HSA-5578775
SARS-CoV Infections R-HSA-9679506
Basigin interactions R-HSA-210991
Muscle contraction R-HSA-397014
Hemostasis R-HSA-109582
Disease R-HSA-1643685
Muscle contraction R-HSA-397014
Hemostasis R-HSA-109582
Cell surface interactions at the vascular wall R-HSA-202733
SARS-CoV Infections R-HSA-9679506
Ion channel transport R-HSA-983712
Ion homeostasis R-HSA-5578775
Ion transport by P-type ATPases R-HSA-936837
Infectious disease R-HSA-5663205
Potential therapeutics for SARS R-HSA-9679191
Basigin interactions R-HSA-210991
Transport of small molecules R-HSA-382551
Cardiac conduction R-HSA-5576891
Disease R-HSA-1643685
Muscle contraction R-HSA-397014
Ion transport by P-type ATPases R-HSA-936837
Transport of small molecules R-HSA-382551
Infectious disease R-HSA-5663205
Ion channel transport R-HSA-983712
Ion homeostasis R-HSA-5578775
Potential therapeutics for SARS R-HSA-9679191
Hemostasis R-HSA-109582
Cell surface interactions at the vascular wall R-HSA-202733
Basigin interactions R-HSA-210991
SARS-CoV Infections R-HSA-9679506
Cardiac conduction R-HSA-5576891

Expression Atlas ENSG00000129244
NCBI gene (formerly Entrezgene) 482
GeneCards 805
HGNC Symbol HGNC:805
MIM gene 182331
UniProtKB Gene Name P14415
WikiGene 482
Gene: PSENEN
Ensembl ID : ENSG00000205155
Description: presenilin enhancer, gamma-secretase subunit
Gene Synonyms: PEN2
5 APIs:
185 Possible Orthologues:

Signaling by ERBB4 R-HSA-1236394
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH1 R-HSA-1980143
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
p75 NTR receptor-mediated signalling R-HSA-193704
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH4 R-HSA-9013694
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Regulated proteolysis of p75NTR R-HSA-193692
Amyloid fiber formation R-HSA-977225
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH2 R-HSA-1980145
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-Ephrin signaling R-HSA-2682334
Signaling by ERBB4 R-HSA-1236394
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulated proteolysis of p75NTR R-HSA-193692
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Developmental Biology R-HSA-1266738
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH2 R-HSA-1980145
Disease R-HSA-1643685
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 R-HSA-1980143
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Amyloid fiber formation R-HSA-977225
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH4 R-HSA-9013694
Noncanonical activation of NOTCH3 R-HSA-9017802
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Axon guidance R-HSA-422475
Metabolism of proteins R-HSA-392499
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
p75 NTR receptor-mediated signalling R-HSA-193704
Nervous system development R-HSA-9675108
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH2 R-HSA-1980145
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Noncanonical activation of NOTCH3 R-HSA-9017802
Death Receptor Signaling R-HSA-73887
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
Nervous system development R-HSA-9675108
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
Nuclear signaling by ERBB4 R-HSA-1251985
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 in Cancer R-HSA-2644603
NRIF signals cell death from the nucleus R-HSA-205043
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
p75 NTR receptor-mediated signalling R-HSA-193704
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH R-HSA-157118
Regulated proteolysis of p75NTR R-HSA-193692
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
EPH-Ephrin signaling R-HSA-2682334
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear signaling by ERBB4 R-HSA-1251985
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH3 R-HSA-9012852
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH2 R-HSA-1980145
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by ERBB4 R-HSA-1236394
Amyloid fiber formation R-HSA-977225
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Death Receptor Signaling R-HSA-73887
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by ERBB4 R-HSA-1236394
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH3 R-HSA-9012852
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Death Receptor Signaling R-HSA-73887
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Regulated proteolysis of p75NTR R-HSA-193692
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH4 R-HSA-9013694
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH2 R-HSA-1980145
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 R-HSA-1980143
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
EPH-Ephrin signaling R-HSA-2682334
Nuclear signaling by ERBB4 R-HSA-1251985
Nuclear signaling by ERBB4 R-HSA-1251985
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
Signaling by ERBB4 R-HSA-1236394
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH3 R-HSA-9012852
Disease R-HSA-1643685
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH4 R-HSA-9013694
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Nervous system development R-HSA-9675108
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Amyloid fiber formation R-HSA-977225
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH2 R-HSA-1980145
Axon guidance R-HSA-422475
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-Ephrin signaling R-HSA-2682334
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH R-HSA-157118
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH2 R-HSA-1980145
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH3 R-HSA-9012852
Noncanonical activation of NOTCH3 R-HSA-9017802
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nervous system development R-HSA-9675108
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Death Receptor Signaling R-HSA-73887
EPH-Ephrin signaling R-HSA-2682334
Metabolism of proteins R-HSA-392499
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Axon guidance R-HSA-422475
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NRIF signals cell death from the nucleus R-HSA-205043
Death Receptor Signaling R-HSA-73887
Disease R-HSA-1643685
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Amyloid fiber formation R-HSA-977225
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 in Cancer R-HSA-2644603
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH3 R-HSA-9012852
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signal Transduction R-HSA-162582
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by ERBB4 R-HSA-1236394
Metabolism of proteins R-HSA-392499
Signaling by NOTCH2 R-HSA-1980145
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 R-HSA-1980143
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Developmental Biology R-HSA-1266738
Noncanonical activation of NOTCH3 R-HSA-9017802
Nervous system development R-HSA-9675108
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Regulated proteolysis of p75NTR R-HSA-193692
Signal Transduction R-HSA-162582
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-Ephrin signaling R-HSA-2682334
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Death Receptor Signaling R-HSA-73887
Metabolism of proteins R-HSA-392499
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH3 R-HSA-9012852
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH R-HSA-157118
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Axon guidance R-HSA-422475
Signaling by NOTCH2 R-HSA-1980145
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 R-HSA-1980143
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 in Cancer R-HSA-2644603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by NOTCH1 in Cancer R-HSA-2644603
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
Death Receptor Signaling R-HSA-73887
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 R-HSA-1980143
Amyloid fiber formation R-HSA-977225
Disease R-HSA-1643685
Signaling by NOTCH2 R-HSA-1980145
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH3 R-HSA-9012852
Nervous system development R-HSA-9675108
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by ERBB4 R-HSA-1236394
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH4 R-HSA-9013694
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NRIF signals cell death from the nucleus R-HSA-205043
p75 NTR receptor-mediated signalling R-HSA-193704
EPH-Ephrin signaling R-HSA-2682334
Axon guidance R-HSA-422475
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Signaling by ERBB4 R-HSA-1236394
Nuclear signaling by ERBB4 R-HSA-1251985
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 in Cancer R-HSA-2644603
EPH-Ephrin signaling R-HSA-2682334
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
Disease R-HSA-1643685
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Amyloid fiber formation R-HSA-977225

Expression Atlas ENSG00000205155
LRG display in Ensembl gene LRG_222
NCBI gene (formerly Entrezgene) 55851
GeneCards 30100
HGNC Symbol HGNC:30100
MIM gene 607632
MIM morbid 613736
UniProtKB Gene Name Q9NZ42
WikiGene 55851
Gene: RPS27
Ensembl ID : ENSG00000177954
Description: ribosomal protein S27
Gene Synonyms: MPS-1,MPS1,S27
4 APIs:
111 Possible Orthologues:

Metabolism R-HSA-1430728
Cellular response to starvation R-HSA-9711097
Influenza Viral RNA Transcription and Replication R-HSA-168273
Signaling by Rho GTPases R-HSA-194315
Mitotic Anaphase R-HSA-68882
Metabolism of RNA R-HSA-8953854
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Signaling by ROBO receptors R-HSA-376176
Disease R-HSA-1643685
Translation initiation complex formation R-HSA-72649
SARS-CoV Infections R-HSA-9679506
Infectious disease R-HSA-5663205
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
SARS-CoV-1-host interactions R-HSA-9692914
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
SARS-CoV-2-host interactions R-HSA-9705683
Cellular responses to stimuli R-HSA-8953897
Formation of a pool of free 40S subunits R-HSA-72689
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Axon guidance R-HSA-422475
SARS-CoV-2 Infection R-HSA-9694516
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Eukaryotic Translation Termination R-HSA-72764
rRNA processing R-HSA-72312
Selenoamino acid metabolism R-HSA-2408522
Cell Cycle, Mitotic R-HSA-69278
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle R-HSA-1640170
Developmental Biology R-HSA-1266738
Selenocysteine synthesis R-HSA-2408557
Metabolism R-HSA-1430728
Eukaryotic Translation Initiation R-HSA-72613
Viral mRNA Translation R-HSA-192823
Cellular responses to stress R-HSA-2262752
M Phase R-HSA-68886
Peptide chain elongation R-HSA-156902
Cap-dependent Translation Initiation R-HSA-72737
Amplification of signal from the kinetochores R-HSA-141424
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Signal Transduction R-HSA-162582
Cell Cycle Checkpoints R-HSA-69620
SARS-CoV-1 Infection R-HSA-9678108
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPases Activate Formins R-HSA-5663220
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
RHO GTPase Effectors R-HSA-195258
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic Spindle Checkpoint R-HSA-69618
Nonsense-Mediated Decay (NMD) R-HSA-927802
Ribosomal scanning and start codon recognition R-HSA-72702
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
Translation R-HSA-72766
Eukaryotic Translation Elongation R-HSA-156842
Separation of Sister Chromatids R-HSA-2467813
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Influenza Infection R-HSA-168255
Mitotic Prometaphase R-HSA-68877
rRNA processing in the nucleus and cytosol R-HSA-8868773
Axon guidance R-HSA-422475
Selenoamino acid metabolism R-HSA-2408522
Cell Cycle Checkpoints R-HSA-69620
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Viral mRNA Translation R-HSA-192823
Mitotic Metaphase and Anaphase R-HSA-2555396
Influenza Infection R-HSA-168255
Peptide chain elongation R-HSA-156902
Metabolism of RNA R-HSA-8953854
Cellular responses to stimuli R-HSA-8953897
Nervous system development R-HSA-9675108
RHO GTPases Activate Formins R-HSA-5663220
Cap-dependent Translation Initiation R-HSA-72737
M Phase R-HSA-68886
Eukaryotic Translation Termination R-HSA-72764
Developmental Biology R-HSA-1266738
Translation R-HSA-72766
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
SARS-CoV-2 Infection R-HSA-9694516
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Ribosomal scanning and start codon recognition R-HSA-72702
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
rRNA processing R-HSA-72312
Signal Transduction R-HSA-162582
Cell Cycle R-HSA-1640170
Cellular response to starvation R-HSA-9711097
Disease R-HSA-1643685
Metabolism R-HSA-1430728
Separation of Sister Chromatids R-HSA-2467813
Signaling by ROBO receptors R-HSA-376176
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Eukaryotic Translation Initiation R-HSA-72613
Amplification of signal from the kinetochores R-HSA-141424
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of proteins R-HSA-392499
Mitotic Prometaphase R-HSA-68877
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Formation of a pool of free 40S subunits R-HSA-72689
rRNA processing in the nucleus and cytosol R-HSA-8868773
Mitotic Spindle Checkpoint R-HSA-69618
SARS-CoV Infections R-HSA-9679506
Selenocysteine synthesis R-HSA-2408557
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stress R-HSA-2262752
RHO GTPase Effectors R-HSA-195258
Nonsense-Mediated Decay (NMD) R-HSA-927802
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV-2-host interactions R-HSA-9705683
Influenza Viral RNA Transcription and Replication R-HSA-168273
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
SARS-CoV-1 Infection R-HSA-9678108
Signaling by Rho GTPases R-HSA-194315
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Mitotic Anaphase R-HSA-68882
Infectious disease R-HSA-5663205
Eukaryotic Translation Elongation R-HSA-156842
Translation initiation complex formation R-HSA-72649
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
SARS-CoV-1-host interactions R-HSA-9692914
Metabolism R-HSA-1430728
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Nonsense-Mediated Decay (NMD) R-HSA-927802
Cell Cycle, Mitotic R-HSA-69278
RHO GTPases Activate Formins R-HSA-5663220
Nervous system development R-HSA-9675108
Mitotic Prometaphase R-HSA-68877
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Metabolism of proteins R-HSA-392499
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
rRNA processing R-HSA-72312
Cellular response to starvation R-HSA-9711097
Viral mRNA Translation R-HSA-192823
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Translation initiation complex formation R-HSA-72649
M Phase R-HSA-68886
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Selenoamino acid metabolism R-HSA-2408522
SARS-CoV-1 Infection R-HSA-9678108
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Eukaryotic Translation Termination R-HSA-72764
SARS-CoV-2-host interactions R-HSA-9705683
rRNA processing in the nucleus and cytosol R-HSA-8868773
Formation of a pool of free 40S subunits R-HSA-72689
Cap-dependent Translation Initiation R-HSA-72737
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Signaling by ROBO receptors R-HSA-376176
Influenza Viral RNA Transcription and Replication R-HSA-168273
SARS-CoV-2 Infection R-HSA-9694516
Separation of Sister Chromatids R-HSA-2467813
Selenocysteine synthesis R-HSA-2408557
Eukaryotic Translation Initiation R-HSA-72613
Mitotic Spindle Checkpoint R-HSA-69618
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase Effectors R-HSA-195258
Influenza Infection R-HSA-168255
Signal Transduction R-HSA-162582
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Translation R-HSA-72766
Mitotic Anaphase R-HSA-68882
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic Metaphase and Anaphase R-HSA-2555396
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Metabolism of RNA R-HSA-8953854
SARS-CoV Infections R-HSA-9679506
Infectious disease R-HSA-5663205
Cell Cycle R-HSA-1640170
Ribosomal scanning and start codon recognition R-HSA-72702
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stress R-HSA-2262752
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
SARS-CoV-1-host interactions R-HSA-9692914
Peptide chain elongation R-HSA-156902
Cell Cycle Checkpoints R-HSA-69620
Amplification of signal from the kinetochores R-HSA-141424
Signaling by Rho GTPases R-HSA-194315
Eukaryotic Translation Elongation R-HSA-156842
Axon guidance R-HSA-422475
Disease R-HSA-1643685
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
Metabolism of amino acids and derivatives R-HSA-71291
Selenoamino acid metabolism R-HSA-2408522
SARS-CoV-1 Infection R-HSA-9678108
Selenocysteine synthesis R-HSA-2408557
rRNA processing R-HSA-72312
Eukaryotic Translation Initiation R-HSA-72613
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
RHO GTPase Effectors R-HSA-195258
Metabolism of RNA R-HSA-8953854
Nervous system development R-HSA-9675108
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
SARS-CoV Infections R-HSA-9679506
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Cap-dependent Translation Initiation R-HSA-72737
rRNA processing in the nucleus and cytosol R-HSA-8868773
SARS-CoV-1-host interactions R-HSA-9692914
Ribosomal scanning and start codon recognition R-HSA-72702
Resolution of Sister Chromatid Cohesion R-HSA-2500257
RHO GTPases Activate Formins R-HSA-5663220
Influenza Infection R-HSA-168255
Infectious disease R-HSA-5663205
Eukaryotic Translation Termination R-HSA-72764
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Translation initiation complex formation R-HSA-72649
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
Cellular response to starvation R-HSA-9711097
Cellular responses to stress R-HSA-2262752
Eukaryotic Translation Elongation R-HSA-156842
Formation of a pool of free 40S subunits R-HSA-72689
Mitotic Spindle Checkpoint R-HSA-69618
Separation of Sister Chromatids R-HSA-2467813
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Mitotic Prometaphase R-HSA-68877
Cell Cycle Checkpoints R-HSA-69620
Signaling by ROBO receptors R-HSA-376176
Signaling by Rho GTPases R-HSA-194315
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
SARS-CoV-2-host interactions R-HSA-9705683
M Phase R-HSA-68886
Nonsense-Mediated Decay (NMD) R-HSA-927802
SARS-CoV-2 Infection R-HSA-9694516
Translation R-HSA-72766
Mitotic Anaphase R-HSA-68882
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Viral mRNA Translation R-HSA-192823
Amplification of signal from the kinetochores R-HSA-141424
Metabolism of proteins R-HSA-392499
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Influenza Viral RNA Transcription and Replication R-HSA-168273
Metabolism R-HSA-1430728
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Peptide chain elongation R-HSA-156902
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Cell Cycle R-HSA-1640170
SARS-CoV Infections R-HSA-9679506
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism R-HSA-1430728
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Mitotic Metaphase and Anaphase R-HSA-2555396
SARS-CoV-1-host interactions R-HSA-9692914
Signaling by ROBO receptors R-HSA-376176
Viral mRNA Translation R-HSA-192823
Cellular responses to stress R-HSA-2262752
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Translation initiation complex formation R-HSA-72649
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
SARS-CoV-1 Infection R-HSA-9678108
Infectious disease R-HSA-5663205
Amplification of signal from the kinetochores R-HSA-141424
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
Formation of a pool of free 40S subunits R-HSA-72689
SARS-CoV-2 Infection R-HSA-9694516
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Metabolism of RNA R-HSA-8953854
Separation of Sister Chromatids R-HSA-2467813
Signaling by Rho GTPases R-HSA-194315
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stimuli R-HSA-8953897
Axon guidance R-HSA-422475
Translation R-HSA-72766
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
RHO GTPase Effectors R-HSA-195258
Cap-dependent Translation Initiation R-HSA-72737
Metabolism of proteins R-HSA-392499
Ribosomal scanning and start codon recognition R-HSA-72702
rRNA processing in the nucleus and cytosol R-HSA-8868773
RHO GTPases Activate Formins R-HSA-5663220
Selenoamino acid metabolism R-HSA-2408522
Selenocysteine synthesis R-HSA-2408557
Mitotic Prometaphase R-HSA-68877
Eukaryotic Translation Elongation R-HSA-156842
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Influenza Infection R-HSA-168255
Metabolism of amino acids and derivatives R-HSA-71291
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
SARS-CoV-2-host interactions R-HSA-9705683
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
Peptide chain elongation R-HSA-156902
Mitotic Spindle Checkpoint R-HSA-69618
Mitotic Anaphase R-HSA-68882
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Eukaryotic Translation Initiation R-HSA-72613
Cellular response to starvation R-HSA-9711097
Nonsense-Mediated Decay (NMD) R-HSA-927802
Eukaryotic Translation Termination R-HSA-72764
M Phase R-HSA-68886
rRNA processing R-HSA-72312
Influenza Viral RNA Transcription and Replication R-HSA-168273
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Translation R-HSA-72766
M Phase R-HSA-68886
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Amplification of signal from the kinetochores R-HSA-141424
rRNA processing in the nucleus and cytosol R-HSA-8868773
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Metabolism of amino acids and derivatives R-HSA-71291
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Signaling by ROBO receptors R-HSA-376176
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SARS-CoV Infections R-HSA-9679506
Separation of Sister Chromatids R-HSA-2467813
Disease R-HSA-1643685
Mitotic Spindle Checkpoint R-HSA-69618
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Infectious disease R-HSA-5663205
SARS-CoV-2 Infection R-HSA-9694516
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Axon guidance R-HSA-422475
Selenoamino acid metabolism R-HSA-2408522
Influenza Infection R-HSA-168255
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Eukaryotic Translation Termination R-HSA-72764
Cap-dependent Translation Initiation R-HSA-72737
Metabolism of proteins R-HSA-392499
Cellular response to starvation R-HSA-9711097
Formation of a pool of free 40S subunits R-HSA-72689
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cell Cycle Checkpoints R-HSA-69620
Selenocysteine synthesis R-HSA-2408557
Cell Cycle R-HSA-1640170
RHO GTPases Activate Formins R-HSA-5663220
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Signal Transduction R-HSA-162582
Eukaryotic Translation Initiation R-HSA-72613
SARS-CoV-1 Infection R-HSA-9678108
Metabolism R-HSA-1430728
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
rRNA processing R-HSA-72312
Nonsense-Mediated Decay (NMD) R-HSA-927802
Metabolism of RNA R-HSA-8953854
Influenza Viral RNA Transcription and Replication R-HSA-168273
Signaling by Rho GTPases R-HSA-194315
Nervous system development R-HSA-9675108
Ribosomal scanning and start codon recognition R-HSA-72702
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Cellular responses to stimuli R-HSA-8953897
Mitotic Prometaphase R-HSA-68877
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
SARS-CoV-2-host interactions R-HSA-9705683
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
SARS-CoV-1-host interactions R-HSA-9692914
Mitotic Anaphase R-HSA-68882
Peptide chain elongation R-HSA-156902
Viral mRNA Translation R-HSA-192823
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
RHO GTPase Effectors R-HSA-195258
Mitotic Metaphase and Anaphase R-HSA-2555396
Translation initiation complex formation R-HSA-72649
Eukaryotic Translation Elongation R-HSA-156842
Developmental Biology R-HSA-1266738
Cellular responses to stress R-HSA-2262752
Eukaryotic Translation Initiation R-HSA-72613
Peptide chain elongation R-HSA-156902
Eukaryotic Translation Termination R-HSA-72764
Disease R-HSA-1643685
SARS-CoV-2-host interactions R-HSA-9705683
Mitotic Spindle Checkpoint R-HSA-69618
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Metabolism of RNA R-HSA-8953854
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
Cellular response to starvation R-HSA-9711097
Cellular responses to stress R-HSA-2262752
Selenocysteine synthesis R-HSA-2408557
Eukaryotic Translation Elongation R-HSA-156842
SARS-CoV-1 Infection R-HSA-9678108
Nonsense-Mediated Decay (NMD) R-HSA-927802
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Mitotic Prometaphase R-HSA-68877
Mitotic Metaphase and Anaphase R-HSA-2555396
Translation initiation complex formation R-HSA-72649
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Nervous system development R-HSA-9675108
Influenza Infection R-HSA-168255
Amplification of signal from the kinetochores R-HSA-141424
Metabolism of proteins R-HSA-392499
Translation R-HSA-72766
Infectious disease R-HSA-5663205
Metabolism R-HSA-1430728
Ribosomal scanning and start codon recognition R-HSA-72702
Cell Cycle Checkpoints R-HSA-69620
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Mitotic Anaphase R-HSA-68882
Cellular responses to stimuli R-HSA-8953897
Viral mRNA Translation R-HSA-192823
RHO GTPases Activate Formins R-HSA-5663220
Separation of Sister Chromatids R-HSA-2467813
Cap-dependent Translation Initiation R-HSA-72737
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Influenza Viral RNA Transcription and Replication R-HSA-168273
Metabolism of amino acids and derivatives R-HSA-71291
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Cell Cycle R-HSA-1640170
Selenoamino acid metabolism R-HSA-2408522
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase Effectors R-HSA-195258
Signaling by ROBO receptors R-HSA-376176
Cell Cycle, Mitotic R-HSA-69278
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
SARS-CoV Infections R-HSA-9679506
rRNA processing R-HSA-72312
rRNA processing in the nucleus and cytosol R-HSA-8868773
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SARS-CoV-2 Infection R-HSA-9694516
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
M Phase R-HSA-68886
Developmental Biology R-HSA-1266738
Formation of a pool of free 40S subunits R-HSA-72689
Signaling by Rho GTPases R-HSA-194315
SARS-CoV-1-host interactions R-HSA-9692914
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Disease R-HSA-1643685
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Nervous system development R-HSA-9675108
Peptide chain elongation R-HSA-156902
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle, Mitotic R-HSA-69278
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
RHO GTPase Effectors R-HSA-195258
Cellular responses to stimuli R-HSA-8953897
Cell Cycle R-HSA-1640170
Translation initiation complex formation R-HSA-72649
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
Eukaryotic Translation Initiation R-HSA-72613
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of amino acids and derivatives R-HSA-71291
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Viral mRNA Translation R-HSA-192823
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Influenza Viral RNA Transcription and Replication R-HSA-168273
M Phase R-HSA-68886
Mitotic Anaphase R-HSA-68882
Axon guidance R-HSA-422475
Cellular responses to stress R-HSA-2262752
Signaling by ROBO receptors R-HSA-376176
SARS-CoV Infections R-HSA-9679506
SARS-CoV-1-host interactions R-HSA-9692914
Infectious disease R-HSA-5663205
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Cell Cycle Checkpoints R-HSA-69620
Formation of a pool of free 40S subunits R-HSA-72689
Translation R-HSA-72766
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Cap-dependent Translation Initiation R-HSA-72737
Metabolism of RNA R-HSA-8953854
Metabolism of proteins R-HSA-392499
SARS-CoV-1 Infection R-HSA-9678108
Separation of Sister Chromatids R-HSA-2467813
Ribosomal scanning and start codon recognition R-HSA-72702
Amplification of signal from the kinetochores R-HSA-141424
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
RHO GTPases Activate Formins R-HSA-5663220
Selenoamino acid metabolism R-HSA-2408522
Selenocysteine synthesis R-HSA-2408557
rRNA processing in the nucleus and cytosol R-HSA-8868773
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Eukaryotic Translation Elongation R-HSA-156842
Signaling by Rho GTPases R-HSA-194315
Developmental Biology R-HSA-1266738
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Eukaryotic Translation Termination R-HSA-72764
Cellular response to starvation R-HSA-9711097
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Influenza Infection R-HSA-168255
Signal Transduction R-HSA-162582
Nonsense-Mediated Decay (NMD) R-HSA-927802
SARS-CoV-2 Infection R-HSA-9694516
Mitotic Spindle Checkpoint R-HSA-69618
SARS-CoV-2-host interactions R-HSA-9705683
rRNA processing R-HSA-72312
Mitotic Prometaphase R-HSA-68877
RHO GTPase Effectors R-HSA-195258
Translation R-HSA-72766
RHO GTPases Activate Formins R-HSA-5663220
Eukaryotic Translation Initiation R-HSA-72613
SARS-CoV-1 Infection R-HSA-9678108
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Selenocysteine synthesis R-HSA-2408557
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Cellular response to starvation R-HSA-9711097
Cell Cycle Checkpoints R-HSA-69620
Peptide chain elongation R-HSA-156902
Developmental Biology R-HSA-1266738
Amplification of signal from the kinetochores R-HSA-141424
Translation initiation complex formation R-HSA-72649
M Phase R-HSA-68886
Signaling by ROBO receptors R-HSA-376176
SARS-CoV-1-host interactions R-HSA-9692914
Separation of Sister Chromatids R-HSA-2467813
Cellular responses to stress R-HSA-2262752
Formation of a pool of free 40S subunits R-HSA-72689
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Mitotic Anaphase R-HSA-68882
Nonsense-Mediated Decay (NMD) R-HSA-927802
Signal Transduction R-HSA-162582
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Cell Cycle, Mitotic R-HSA-69278
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Influenza Infection R-HSA-168255
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Selenoamino acid metabolism R-HSA-2408522
Ribosomal scanning and start codon recognition R-HSA-72702
Axon guidance R-HSA-422475
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
SARS-CoV Infections R-HSA-9679506
Eukaryotic Translation Termination R-HSA-72764
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Metabolism of RNA R-HSA-8953854
SARS-CoV-2-host interactions R-HSA-9705683
Viral mRNA Translation R-HSA-192823
Nervous system development R-HSA-9675108
Signaling by Rho GTPases R-HSA-194315
Regulation of expression of SLITs and ROBOs R-HSA-9010553
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Influenza Viral RNA Transcription and Replication R-HSA-168273
Eukaryotic Translation Elongation R-HSA-156842
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
rRNA processing in the nucleus and cytosol R-HSA-8868773
rRNA processing R-HSA-72312
Cell Cycle R-HSA-1640170
Metabolism of proteins R-HSA-392499
Cellular responses to stimuli R-HSA-8953897
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Cap-dependent Translation Initiation R-HSA-72737
Mitotic Spindle Checkpoint R-HSA-69618
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
SARS-CoV-2 Infection R-HSA-9694516
Mitotic Prometaphase R-HSA-68877
Translation R-HSA-72766
Eukaryotic Translation Initiation R-HSA-72613
SARS-CoV Infections R-HSA-9679506
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Cell Cycle Checkpoints R-HSA-69620
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stress R-HSA-2262752
Viral mRNA Translation R-HSA-192823
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Ribosomal scanning and start codon recognition R-HSA-72702
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Metabolism of amino acids and derivatives R-HSA-71291
Developmental Biology R-HSA-1266738
RHO GTPases Activate Formins R-HSA-5663220
Axon guidance R-HSA-422475
Cellular responses to stimuli R-HSA-8953897
Nervous system development R-HSA-9675108
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Nonsense-Mediated Decay (NMD) R-HSA-927802
Cap-dependent Translation Initiation R-HSA-72737
Mitotic Prometaphase R-HSA-68877
Influenza Infection R-HSA-168255
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444
SARS-CoV-2-host interactions R-HSA-9705683
Cellular response to starvation R-HSA-9711097
Mitotic Metaphase and Anaphase R-HSA-2555396
Peptide chain elongation R-HSA-156902
Formation of a pool of free 40S subunits R-HSA-72689
Separation of Sister Chromatids R-HSA-2467813
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Signaling by ROBO receptors R-HSA-376176
RHO GTPase Effectors R-HSA-195258
Influenza Viral RNA Transcription and Replication R-HSA-168273
Selenoamino acid metabolism R-HSA-2408522
Cell Cycle R-HSA-1640170
rRNA processing R-HSA-72312
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Selenocysteine synthesis R-HSA-2408557
Disease R-HSA-1643685
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-2 Infection R-HSA-9694516
Metabolism R-HSA-1430728
Signaling by Rho GTPases R-HSA-194315
Eukaryotic Translation Elongation R-HSA-156842
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Infectious disease R-HSA-5663205
Mitotic Spindle Checkpoint R-HSA-69618
Translation initiation complex formation R-HSA-72649
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Eukaryotic Translation Termination R-HSA-72764
SARS-CoV-1-host interactions R-HSA-9692914
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Signal Transduction R-HSA-162582
M Phase R-HSA-68886
Metabolism of proteins R-HSA-392499
Metabolism of RNA R-HSA-8953854
rRNA processing in the nucleus and cytosol R-HSA-8868773
Amplification of signal from the kinetochores R-HSA-141424
Mitotic Anaphase R-HSA-68882

Expression Atlas ENSG00000177954
LRG display in Ensembl gene LRG_1158
NCBI gene (formerly Entrezgene) 6232
GeneCards 10416
HGNC Symbol HGNC:10416
MIM gene 603702
MIM morbid 617409
UniProtKB Gene Name P42677
WikiGene 6232
Gene: PSMA2
Ensembl ID : ENSG00000106588
Description: proteasome 20S subunit alpha 2
Gene Synonyms: HC3,MU,PMSA2
6 APIs:
231 Possible Orthologues:

Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by NOTCH4 R-HSA-9013694
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Metabolism of proteins R-HSA-392499
Signaling by NOTCH R-HSA-157118
Regulation of Apoptosis R-HSA-169911
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of DVL R-HSA-4641258
Activation of NF-kappaB in B cells R-HSA-1169091
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stimuli R-HSA-8953897
ABC transporter disorders R-HSA-5619084
UCH proteinases R-HSA-5689603
Cellular responses to stress R-HSA-2262752
Regulation of PTEN stability and activity R-HSA-8948751
MAPK6/MAPK4 signaling R-HSA-5687128
Host Interactions of HIV factors R-HSA-162909
RAF/MAP kinase cascade R-HSA-5673001
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of GLI1 by the proteasome R-HSA-5610780
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Downstream TCR signaling R-HSA-202424
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of mitotic cell cycle R-HSA-453276
Innate Immune System R-HSA-168249
Ub-specific processing proteases R-HSA-5689880
Vpu mediated degradation of CD4 R-HSA-180534
G1/S DNA Damage Checkpoints R-HSA-69615
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
DNA Replication R-HSA-69306
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Hedgehog 'off' state R-HSA-5610787
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of GLI2 by the proteasome R-HSA-5610783
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FCERI mediated NF-kB activation R-HSA-2871837
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
Neddylation R-HSA-8951664
Adaptive Immune System R-HSA-1280218
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Synthesis of DNA R-HSA-69239
ER-Phagosome pathway R-HSA-1236974
Disorders of transmembrane transporters R-HSA-5619115
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of polyamines R-HSA-351202
Post-translational protein modification R-HSA-597592
Signaling by WNT R-HSA-195721
PIP3 activates AKT signaling R-HSA-1257604
S Phase R-HSA-69242
Assembly of the pre-replicative complex R-HSA-68867
Gene expression (Transcription) R-HSA-74160
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX3 expression and activity R-HSA-8941858
Neutrophil degranulation R-HSA-6798695
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Anaphase R-HSA-68882
Mitotic G2-G2/M phases R-HSA-453274
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX1 R-HSA-8878171
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
Metabolism of RNA R-HSA-8953854
Transport of small molecules R-HSA-382551
Degradation of AXIN R-HSA-4641257
G2/M Transition R-HSA-69275
Antigen processing-Cross presentation R-HSA-1236975
Programmed Cell Death R-HSA-5357801
PTEN Regulation R-HSA-6807070
Nuclear events mediated by NFE2L2 R-HSA-9759194
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
ABC-family proteins mediated transport R-HSA-382556
G1/S Transition R-HSA-69206
Class I MHC mediated antigen processing & presentation R-HSA-983169
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to hypoxia R-HSA-1234174
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
HIV Infection R-HSA-162906
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Hedgehog R-HSA-5358351
Hh mutants are degraded by ERAD R-HSA-5362768
Nervous system development R-HSA-9675108
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cellular response to chemical stress R-HSA-9711123
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
M Phase R-HSA-68886
Metabolism R-HSA-1430728
G2/M Checkpoints R-HSA-69481
Orc1 removal from chromatin R-HSA-68949
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'on' state R-HSA-5632684
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
DNA Replication Pre-Initiation R-HSA-69002
Stabilization of p53 R-HSA-69541
Axon guidance R-HSA-422475
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of amino acids and derivatives R-HSA-71291
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Deubiquitination R-HSA-5688426
Interleukin-1 family signaling R-HSA-446652
TCR signaling R-HSA-202403
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Separation of Sister Chromatids R-HSA-2467813
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of beta-catenin by the destruction complex R-HSA-195253
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of AXIN R-HSA-4641257
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Beta-catenin independent WNT signaling R-HSA-3858494
Post-translational protein modification R-HSA-597592
Axon guidance R-HSA-422475
Signaling by Hedgehog R-HSA-5358351
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Host Interactions of HIV factors R-HSA-162909
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cell Cycle R-HSA-1640170
TCF dependent signaling in response to WNT R-HSA-201681
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Vpu mediated degradation of CD4 R-HSA-180534
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Asymmetric localization of PCP proteins R-HSA-4608870
Neddylation R-HSA-8951664
p53-Independent DNA Damage Response R-HSA-69610
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of PTEN stability and activity R-HSA-8948751
G1/S DNA Damage Checkpoints R-HSA-69615
TCR signaling R-HSA-202403
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transport of small molecules R-HSA-382551
Metabolism of RNA R-HSA-8953854
ABC-family proteins mediated transport R-HSA-382556
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'off' state R-HSA-5610787
Signaling by WNT R-HSA-195721
Metabolism of amino acids and derivatives R-HSA-71291
Separation of Sister Chromatids R-HSA-2467813
Gene expression (Transcription) R-HSA-74160
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
Cellular response to hypoxia R-HSA-1234174
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle, Mitotic R-HSA-69278
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cytokine Signaling in Immune system R-HSA-1280215
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of beta-catenin by the destruction complex R-HSA-195253
DNA Replication R-HSA-69306
M Phase R-HSA-68886
Nuclear events mediated by NFE2L2 R-HSA-9759194
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of DVL R-HSA-4641258
Activation of NF-kappaB in B cells R-HSA-1169091
Innate Immune System R-HSA-168249
Apoptosis R-HSA-109581
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CLEC7A (Dectin-1) signaling R-HSA-5607764
S Phase R-HSA-69242
UCH proteinases R-HSA-5689603
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
FCERI mediated NF-kB activation R-HSA-2871837
PIP3 activates AKT signaling R-HSA-1257604
Downstream TCR signaling R-HSA-202424
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Synthesis of DNA R-HSA-69239
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
Orc1 removal from chromatin R-HSA-68949
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Metabolism of proteins R-HSA-392499
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Cellular responses to stress R-HSA-2262752
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
ABC transporter disorders R-HSA-5619084
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK family signaling cascades R-HSA-5683057
G2/M Transition R-HSA-69275
MAPK1/MAPK3 signaling R-HSA-5684996
PTEN Regulation R-HSA-6807070
Cellular responses to stimuli R-HSA-8953897
Mitotic Anaphase R-HSA-68882
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog 'on' state R-HSA-5632684
Vif-mediated degradation of APOBEC3G R-HSA-180585
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signal Transduction R-HSA-162582
Degradation of GLI1 by the proteasome R-HSA-5610780
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Interleukin-1 signaling R-HSA-9020702
DNA Replication Pre-Initiation R-HSA-69002
Neutrophil degranulation R-HSA-6798695
Ub-specific processing proteases R-HSA-5689880
Switching of origins to a post-replicative state R-HSA-69052
Nervous system development R-HSA-9675108
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
Cyclin E associated events during G1/S transition R-HSA-69202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
Deubiquitination R-HSA-5688426
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
PCP/CE pathway R-HSA-4086400
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle Checkpoints R-HSA-69620
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of polyamines R-HSA-351202
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by NOTCH R-HSA-157118
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
TCR signaling R-HSA-202403
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Beta-catenin independent WNT signaling R-HSA-3858494
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of RNA R-HSA-8953854
Separation of Sister Chromatids R-HSA-2467813
Adaptive Immune System R-HSA-1280218
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Infectious disease R-HSA-5663205
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Axon guidance R-HSA-422475
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by WNT R-HSA-195721
Metabolism of polyamines R-HSA-351202
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Developmental Biology R-HSA-1266738
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Neddylation R-HSA-8951664
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'off' state R-HSA-5610787
Metabolism of amino acids and derivatives R-HSA-71291
Disorders of transmembrane transporters R-HSA-5619115
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nuclear events mediated by NFE2L2 R-HSA-9759194
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Checkpoints R-HSA-69481
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of proteins R-HSA-392499
Cellular response to chemical stress R-HSA-9711123
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
Downstream TCR signaling R-HSA-202424
Mitotic G2-G2/M phases R-HSA-453274
Mitotic G1 phase and G1/S transition R-HSA-453279
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
HIV Infection R-HSA-162906
Transcriptional regulation by RUNX2 R-HSA-8878166
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of GLI2 by the proteasome R-HSA-5610783
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Synthesis of DNA R-HSA-69239
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transport of small molecules R-HSA-382551
Signaling by NOTCH4 R-HSA-9013694
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PTEN Regulation R-HSA-6807070
Post-translational protein modification R-HSA-597592
Intracellular signaling by second messengers R-HSA-9006925
CLEC7A (Dectin-1) signaling R-HSA-5607764
UCH proteinases R-HSA-5689603
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Defective CFTR causes cystic fibrosis R-HSA-5678895
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ABC-family proteins mediated transport R-HSA-382556
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of Apoptosis R-HSA-169911
S Phase R-HSA-69242
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 signaling R-HSA-9020702
DNA Replication R-HSA-69306
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of AXIN R-HSA-4641257
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
Cell Cycle, Mitotic R-HSA-69278
Assembly of the pre-replicative complex R-HSA-68867
Signal Transduction R-HSA-162582
PCP/CE pathway R-HSA-4086400
Regulation of RAS by GAPs R-HSA-5658442
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Programmed Cell Death R-HSA-5357801
Cellular response to hypoxia R-HSA-1234174
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH R-HSA-157118
ER-Phagosome pathway R-HSA-1236974
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Hedgehog R-HSA-5358351
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK1/MAPK3 signaling R-HSA-5684996
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cell Cycle Checkpoints R-HSA-69620
M Phase R-HSA-68886
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Gene expression (Transcription) R-HSA-74160
Neutrophil degranulation R-HSA-6798695
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
G1/S Transition R-HSA-69206
Class I MHC mediated antigen processing & presentation R-HSA-983169
RNA Polymerase II Transcription R-HSA-73857
MAPK6/MAPK4 signaling R-HSA-5687128
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX3 R-HSA-8878159
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by Interleukins R-HSA-449147
Degradation of DVL R-HSA-4641258
Vpu mediated degradation of CD4 R-HSA-180534
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
DNA Replication R-HSA-69306
Post-translational protein modification R-HSA-597592
TCF dependent signaling in response to WNT R-HSA-201681
Vpu mediated degradation of CD4 R-HSA-180534
ABC-family proteins mediated transport R-HSA-382556
Axon guidance R-HSA-422475
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Programmed Cell Death R-HSA-5357801
Asymmetric localization of PCP proteins R-HSA-4608870
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK6/MAPK4 signaling R-HSA-5687128
Deubiquitination R-HSA-5688426
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Infectious disease R-HSA-5663205
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX2 expression and activity R-HSA-8939902
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
Vif-mediated degradation of APOBEC3G R-HSA-180585
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by WNT R-HSA-195721
p53-Dependent G1 DNA Damage Response R-HSA-69563
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
Metabolism of RNA R-HSA-8953854
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S DNA Damage Checkpoints R-HSA-69615
ABC transporter disorders R-HSA-5619084
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Stabilization of p53 R-HSA-69541
MAPK1/MAPK3 signaling R-HSA-5684996
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Generic Transcription Pathway R-HSA-212436
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of PTEN stability and activity R-HSA-8948751
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular responses to stimuli R-HSA-8953897
Neutrophil degranulation R-HSA-6798695
Metabolism of polyamines R-HSA-351202
Cellular response to chemical stress R-HSA-9711123
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants are degraded by ERAD R-HSA-5362768
Hedgehog 'off' state R-HSA-5610787
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by ROBO receptors R-HSA-376176
Regulation of mitotic cell cycle R-HSA-453276
HIV Infection R-HSA-162906
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog ligand biogenesis R-HSA-5358346
Downstream TCR signaling R-HSA-202424
G1/S Transition R-HSA-69206
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX1 R-HSA-8878171
Cytokine Signaling in Immune system R-HSA-1280215
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog 'on' state R-HSA-5632684
Regulation of Apoptosis R-HSA-169911
Synthesis of DNA R-HSA-69239
TCR signaling R-HSA-202403
Metabolism of amino acids and derivatives R-HSA-71291
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G2-G2/M phases R-HSA-453274
Nervous system development R-HSA-9675108
Assembly of the pre-replicative complex R-HSA-68867
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
UCH proteinases R-HSA-5689603
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
Regulation of expression of SLITs and ROBOs R-HSA-9010553
S Phase R-HSA-69242
Mitotic Anaphase R-HSA-68882
M Phase R-HSA-68886
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Host Interactions of HIV factors R-HSA-162909
p53-Independent DNA Damage Response R-HSA-69610
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Disorders of transmembrane transporters R-HSA-5619115
PCP/CE pathway R-HSA-4086400
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Hedgehog R-HSA-5358351
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of AXIN R-HSA-4641257
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of DVL R-HSA-4641258
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transport of small molecules R-HSA-382551
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Switching of origins to a post-replicative state R-HSA-69052
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Separation of Sister Chromatids R-HSA-2467813
Cell Cycle, Mitotic R-HSA-69278
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 signaling R-HSA-9020702
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G1 phase and G1/S transition R-HSA-453279
FCERI mediated NF-kB activation R-HSA-2871837
Immune System R-HSA-168256
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH4 R-HSA-9013694
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH R-HSA-157118
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Orc1 removal from chromatin R-HSA-68949
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Orc1 removal from chromatin R-HSA-68949
G2/M Checkpoints R-HSA-69481
Separation of Sister Chromatids R-HSA-2467813
C-type lectin receptors (CLRs) R-HSA-5621481
S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Switching of origins to a post-replicative state R-HSA-69052
Synthesis of DNA R-HSA-69239
DNA Replication Pre-Initiation R-HSA-69002
PCP/CE pathway R-HSA-4086400
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Negative regulation of NOTCH4 signaling R-HSA-9604323
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Developmental Biology R-HSA-1266738
Signaling by Hedgehog R-HSA-5358351
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stimuli R-HSA-8953897
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Interleukins R-HSA-449147
Cellular response to chemical stress R-HSA-9711123
HIV Infection R-HSA-162906
TCR signaling R-HSA-202403
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle R-HSA-1640170
Signaling by WNT R-HSA-195721
p53-Dependent G1 DNA Damage Response R-HSA-69563
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Stabilization of p53 R-HSA-69541
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Regulation of Apoptosis R-HSA-169911
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RAS by GAPs R-HSA-5658442
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX2 R-HSA-8878166
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Immune System R-HSA-168256
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vpu mediated degradation of CD4 R-HSA-180534
Vif-mediated degradation of APOBEC3G R-HSA-180585
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic Metaphase and Anaphase R-HSA-2555396
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transport of small molecules R-HSA-382551
Intracellular signaling by second messengers R-HSA-9006925
Nuclear events mediated by NFE2L2 R-HSA-9759194
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
DNA Replication R-HSA-69306
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of polyamines R-HSA-351202
Neutrophil degranulation R-HSA-6798695
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ub-specific processing proteases R-HSA-5689880
Neddylation R-HSA-8951664
Cell Cycle Checkpoints R-HSA-69620
Mitotic Anaphase R-HSA-68882
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Programmed Cell Death R-HSA-5357801
Degradation of DVL R-HSA-4641258
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Post-translational protein modification R-HSA-597592
Regulation of mitotic cell cycle R-HSA-453276
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of PTEN stability and activity R-HSA-8948751
Hedgehog 'on' state R-HSA-5632684
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Independent DNA Damage Response R-HSA-69610
Interleukin-1 signaling R-HSA-9020702
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CLEC7A (Dectin-1) signaling R-HSA-5607764
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX2 expression and activity R-HSA-8939902
M Phase R-HSA-68886
Signaling by NOTCH R-HSA-157118
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of beta-catenin by the destruction complex R-HSA-195253
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G1/S Transition R-HSA-69206
Signaling by ROBO receptors R-HSA-376176
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transcriptional regulation by RUNX1 R-HSA-8878171
ABC-family proteins mediated transport R-HSA-382556
G1/S DNA Damage Checkpoints R-HSA-69615
Infectious disease R-HSA-5663205
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
ABC transporter disorders R-HSA-5619084
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 family signaling R-HSA-446652
Defective CFTR causes cystic fibrosis R-HSA-5678895
UCH proteinases R-HSA-5689603
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'off' state R-HSA-5610787
Activation of NF-kappaB in B cells R-HSA-1169091
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M Transition R-HSA-69275
PTEN Regulation R-HSA-6807070
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of RNA R-HSA-8953854
Degradation of GLI2 by the proteasome R-HSA-5610783
Apoptosis R-HSA-109581
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism R-HSA-1430728
Cellular response to hypoxia R-HSA-1234174
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
HIV Infection R-HSA-162906
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH R-HSA-157118
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PTEN Regulation R-HSA-6807070
Hh mutants are degraded by ERAD R-HSA-5362768
Separation of Sister Chromatids R-HSA-2467813
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'on' state R-HSA-5632684
Switching of origins to a post-replicative state R-HSA-69052
Synthesis of DNA R-HSA-69239
Regulation of RAS by GAPs R-HSA-5658442
Signaling by NOTCH4 R-HSA-9013694
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cyclin E associated events during G1/S transition R-HSA-69202
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants abrogate ligand secretion R-HSA-5387390
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle, Mitotic R-HSA-69278
Signaling by ROBO receptors R-HSA-376176
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
Interleukin-1 signaling R-HSA-9020702
Post-translational protein modification R-HSA-597592
Nervous system development R-HSA-9675108
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular responses to stimuli R-HSA-8953897
G2/M Checkpoints R-HSA-69481
Nuclear events mediated by NFE2L2 R-HSA-9759194
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle R-HSA-1640170
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX3 expression and activity R-HSA-8941858
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX3 R-HSA-8878159
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Defective CFTR causes cystic fibrosis R-HSA-5678895
Stabilization of p53 R-HSA-69541
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by Interleukins R-HSA-449147
ER-Phagosome pathway R-HSA-1236974
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog 'off' state R-HSA-5610787
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
S Phase R-HSA-69242
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Vpu mediated degradation of CD4 R-HSA-180534
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RAF/MAP kinase cascade R-HSA-5673001
TCF dependent signaling in response to WNT R-HSA-201681
Transport of small molecules R-HSA-382551
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Cytokine Signaling in Immune system R-HSA-1280215
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of RNA R-HSA-8953854
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular responses to stress R-HSA-2262752
DNA Replication R-HSA-69306
ABC transporter disorders R-HSA-5619084
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of polyamines R-HSA-351202
Degradation of beta-catenin by the destruction complex R-HSA-195253
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neutrophil degranulation R-HSA-6798695
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
Innate Immune System R-HSA-168249
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle Checkpoints R-HSA-69620
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ub-specific processing proteases R-HSA-5689880
KEAP1-NFE2L2 pathway R-HSA-9755511
Disorders of transmembrane transporters R-HSA-5619115
Vif-mediated degradation of APOBEC3G R-HSA-180585
Deubiquitination R-HSA-5688426
Hedgehog ligand biogenesis R-HSA-5358346
Orc1 removal from chromatin R-HSA-68949
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism R-HSA-1430728
Class I MHC mediated antigen processing & presentation R-HSA-983169
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular response to chemical stress R-HSA-9711123
Degradation of GLI2 by the proteasome R-HSA-5610783
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
ABC-family proteins mediated transport R-HSA-382556
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
M Phase R-HSA-68886
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of DVL R-HSA-4641258
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
TCR signaling R-HSA-202403
Programmed Cell Death R-HSA-5357801
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
Metabolism R-HSA-1430728
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Class I MHC mediated antigen processing & presentation R-HSA-983169
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
HIV Infection R-HSA-162906
Degradation of DVL R-HSA-4641258
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Hedgehog R-HSA-5358351
Immune System R-HSA-168256
Transcriptional regulation by RUNX1 R-HSA-8878171
ABC-family proteins mediated transport R-HSA-382556
Mitotic Anaphase R-HSA-68882
Cell Cycle R-HSA-1640170
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'on' state R-HSA-5632684
Cytokine Signaling in Immune system R-HSA-1280215
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ER-Phagosome pathway R-HSA-1236974
Apoptosis R-HSA-109581
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Switching of origins to a post-replicative state R-HSA-69052
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication Pre-Initiation R-HSA-69002
Neutrophil degranulation R-HSA-6798695
Transport of small molecules R-HSA-382551
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
M Phase R-HSA-68886
Assembly of the pre-replicative complex R-HSA-68867
G1/S Transition R-HSA-69206
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants are degraded by ERAD R-HSA-5362768
Deubiquitination R-HSA-5688426
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
Cyclin E associated events during G1/S transition R-HSA-69202
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ub-specific processing proteases R-HSA-5689880
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by Interleukins R-HSA-449147
Orc1 removal from chromatin R-HSA-68949
G2/M Transition R-HSA-69275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic G1 phase and G1/S transition R-HSA-453279
Intracellular signaling by second messengers R-HSA-9006925
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Separation of Sister Chromatids R-HSA-2467813
CLEC7A (Dectin-1) signaling R-HSA-5607764
PCP/CE pathway R-HSA-4086400
PTEN Regulation R-HSA-6807070
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication R-HSA-69306
G2/M Checkpoints R-HSA-69481
Cellular response to hypoxia R-HSA-1234174
Cell Cycle, Mitotic R-HSA-69278
Vif-mediated degradation of APOBEC3G R-HSA-180585
Disorders of transmembrane transporters R-HSA-5619115
Cellular response to chemical stress R-HSA-9711123
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of Apoptosis R-HSA-169911
p53-Independent DNA Damage Response R-HSA-69610
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of GLI2 by the proteasome R-HSA-5610783
Defective CFTR causes cystic fibrosis R-HSA-5678895
S Phase R-HSA-69242
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of GLI1 by the proteasome R-HSA-5610780
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of AXIN R-HSA-4641257
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by ROBO receptors R-HSA-376176
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RNA Polymerase II Transcription R-HSA-73857
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 signaling R-HSA-9020702
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RAS by GAPs R-HSA-5658442
Signaling by WNT R-HSA-195721
Post-translational protein modification R-HSA-597592
Disease R-HSA-1643685
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle Checkpoints R-HSA-69620
Negative regulation of NOTCH4 signaling R-HSA-9604323
Synthesis of DNA R-HSA-69239
Metabolism of RNA R-HSA-8953854
TCR signaling R-HSA-202403
UCH proteinases R-HSA-5689603
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX3 R-HSA-8878159
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
MAPK1/MAPK3 signaling R-HSA-5684996
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Gene expression (Transcription) R-HSA-74160
Cellular response to hypoxia R-HSA-1234174
Developmental Biology R-HSA-1266738
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of proteins R-HSA-392499
Antigen processing-Cross presentation R-HSA-1236975
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Neutrophil degranulation R-HSA-6798695
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Neddylation R-HSA-8951664
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S DNA Damage Checkpoints R-HSA-69615
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX2 R-HSA-8878166
Ub-specific processing proteases R-HSA-5689880
NIK-->noncanonical NF-kB signaling R-HSA-5676590
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Negative regulation of NOTCH4 signaling R-HSA-9604323
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
S Phase R-HSA-69242
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
ER-Phagosome pathway R-HSA-1236974
Mitotic G2-G2/M phases R-HSA-453274
MAPK6/MAPK4 signaling R-HSA-5687128
G2/M Checkpoints R-HSA-69481
Regulation of mitotic cell cycle R-HSA-453276
Degradation of GLI2 by the proteasome R-HSA-5610783
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
Cell Cycle R-HSA-1640170
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK1/MAPK3 signaling R-HSA-5684996
Transport of small molecules R-HSA-382551
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
Mitotic G1 phase and G1/S transition R-HSA-453279
ABC-family proteins mediated transport R-HSA-382556
Nuclear events mediated by NFE2L2 R-HSA-9759194
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX3 expression and activity R-HSA-8941858
Orc1 removal from chromatin R-HSA-68949
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Class I MHC mediated antigen processing & presentation R-HSA-983169
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
Axon guidance R-HSA-422475
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
UCH proteinases R-HSA-5689603
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin E associated events during G1/S transition R-HSA-69202
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Metabolism of RNA R-HSA-8953854
FCERI mediated NF-kB activation R-HSA-2871837
Nervous system development R-HSA-9675108
Asymmetric localization of PCP proteins R-HSA-4608870
HIV Infection R-HSA-162906
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Synthesis of DNA R-HSA-69239
Activation of NF-kappaB in B cells R-HSA-1169091
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Disorders of transmembrane transporters R-HSA-5619115
Post-translational protein modification R-HSA-597592
Cellular responses to stress R-HSA-2262752
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by WNT R-HSA-195721
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by NOTCH4 R-HSA-9013694
Metabolism R-HSA-1430728
Assembly of the pre-replicative complex R-HSA-68867
Hedgehog 'off' state R-HSA-5610787
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Stabilization of p53 R-HSA-69541
MAPK family signaling cascades R-HSA-5683057
Signaling by Hedgehog R-HSA-5358351
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hedgehog 'on' state R-HSA-5632684
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disease R-HSA-1643685
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Intracellular signaling by second messengers R-HSA-9006925
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Signaling by ROBO receptors R-HSA-376176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 family signaling R-HSA-446652
G1/S Transition R-HSA-69206
Generic Transcription Pathway R-HSA-212436
Metabolism of polyamines R-HSA-351202
Signaling by Interleukins R-HSA-449147
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
Deubiquitination R-HSA-5688426
Interleukin-1 signaling R-HSA-9020702
Separation of Sister Chromatids R-HSA-2467813
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of AXIN R-HSA-4641257
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle Checkpoints R-HSA-69620
Host Interactions of HIV factors R-HSA-162909
Innate Immune System R-HSA-168249
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Innate Immune System R-HSA-168249
Mitotic G1 phase and G1/S transition R-HSA-453279
Infectious disease R-HSA-5663205
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle, Mitotic R-HSA-69278
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Cellular response to chemical stress R-HSA-9711123
Switching of origins to a post-replicative state R-HSA-69052
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Neddylation R-HSA-8951664
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Dependent G1 DNA Damage Response R-HSA-69563
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transport of small molecules R-HSA-382551
Metabolism of polyamines R-HSA-351202
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'off' state R-HSA-5610787
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent DNA Damage Response R-HSA-69610
Disorders of transmembrane transporters R-HSA-5619115
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cell Cycle Checkpoints R-HSA-69620
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Disease R-HSA-1643685
G2/M Transition R-HSA-69275
G2/M Checkpoints R-HSA-69481
Antigen processing-Cross presentation R-HSA-1236975
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Adaptive Immune System R-HSA-1280218
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication R-HSA-69306
Immune System R-HSA-168256
Hedgehog 'on' state R-HSA-5632684
Metabolism R-HSA-1430728
Cellular responses to stress R-HSA-2262752
ABC transporter disorders R-HSA-5619084
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX3 R-HSA-8878159
Vpu mediated degradation of CD4 R-HSA-180534
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX1 R-HSA-8878171
UCH proteinases R-HSA-5689603
Signaling by Interleukins R-HSA-449147
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX2 R-HSA-8878166
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hh mutants are degraded by ERAD R-HSA-5362768
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK family signaling cascades R-HSA-5683057
Cell Cycle R-HSA-1640170
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MAPK1/MAPK3 signaling R-HSA-5684996
Separation of Sister Chromatids R-HSA-2467813
Interleukin-1 signaling R-HSA-9020702
Post-translational protein modification R-HSA-597592
HIV Infection R-HSA-162906
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Neutrophil degranulation R-HSA-6798695
Degradation of GLI1 by the proteasome R-HSA-5610780
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH4 R-HSA-9013694
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Synthesis of DNA R-HSA-69239
Metabolism of proteins R-HSA-392499
Degradation of DVL R-HSA-4641258
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by Hedgehog R-HSA-5358351
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Assembly of the pre-replicative complex R-HSA-68867
Programmed Cell Death R-HSA-5357801
Signal Transduction R-HSA-162582
DNA Replication Pre-Initiation R-HSA-69002
Signaling by NOTCH R-HSA-157118
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of GLI2 by the proteasome R-HSA-5610783
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Intracellular signaling by second messengers R-HSA-9006925
Class I MHC mediated antigen processing & presentation R-HSA-983169
Activation of NF-kappaB in B cells R-HSA-1169091
Ub-specific processing proteases R-HSA-5689880
RNA Polymerase II Transcription R-HSA-73857
Axon guidance R-HSA-422475
G1/S DNA Damage Checkpoints R-HSA-69615
PTEN Regulation R-HSA-6807070
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular responses to stimuli R-HSA-8953897
Negative regulation of NOTCH4 signaling R-HSA-9604323
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
M Phase R-HSA-68886
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mitotic cell cycle R-HSA-453276
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 family signaling R-HSA-446652
Downstream TCR signaling R-HSA-202424
ABC-family proteins mediated transport R-HSA-382556
Regulation of Apoptosis R-HSA-169911
Developmental Biology R-HSA-1266738
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
RAF/MAP kinase cascade R-HSA-5673001
G1/S Transition R-HSA-69206
Degradation of AXIN R-HSA-4641257
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by WNT R-HSA-195721
PCP/CE pathway R-HSA-4086400
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of PTEN stability and activity R-HSA-8948751
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RAS by GAPs R-HSA-5658442
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
Nervous system development R-HSA-9675108
Neddylation R-HSA-8951664
Degradation of DVL R-HSA-4641258
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signaling by Hedgehog R-HSA-5358351
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Disease R-HSA-1643685
Degradation of AXIN R-HSA-4641257
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1 DNA Damage Response R-HSA-69563
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of RNA R-HSA-8953854
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Interleukin-1 signaling R-HSA-9020702
Mitotic G1 phase and G1/S transition R-HSA-453279
Disorders of transmembrane transporters R-HSA-5619115
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Intracellular signaling by second messengers R-HSA-9006925
ABC-family proteins mediated transport R-HSA-382556
Mitotic Anaphase R-HSA-68882
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PTEN Regulation R-HSA-6807070
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Metabolism of polyamines R-HSA-351202
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
Signaling by WNT R-HSA-195721
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Vpu mediated degradation of CD4 R-HSA-180534
Innate Immune System R-HSA-168249
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Defective CFTR causes cystic fibrosis R-HSA-5678895
Axon guidance R-HSA-422475
Hh mutants are degraded by ERAD R-HSA-5362768
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
PCP/CE pathway R-HSA-4086400
Ub-specific processing proteases R-HSA-5689880
G1/S DNA Damage Checkpoints R-HSA-69615
Post-translational protein modification R-HSA-597592
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Assembly of the pre-replicative complex R-HSA-68867
G2/M Checkpoints R-HSA-69481
M Phase R-HSA-68886
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
C-type lectin receptors (CLRs) R-HSA-5621481
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of proteins R-HSA-392499
Adaptive Immune System R-HSA-1280218
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCF dependent signaling in response to WNT R-HSA-201681
Hh mutants abrogate ligand secretion R-HSA-5387390
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism R-HSA-1430728
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream TCR signaling R-HSA-202424
Cellular responses to stress R-HSA-2262752
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle Checkpoints R-HSA-69620
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vif-mediated degradation of APOBEC3G R-HSA-180585
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Asymmetric localization of PCP proteins R-HSA-4608870
Stabilization of p53 R-HSA-69541
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of Apoptosis R-HSA-169911
UCH proteinases R-HSA-5689603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC transporter disorders R-HSA-5619084
Generic Transcription Pathway R-HSA-212436
Apoptosis R-HSA-109581
Neutrophil degranulation R-HSA-6798695
Cellular responses to stimuli R-HSA-8953897
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
HIV Infection R-HSA-162906
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
DNA Replication Pre-Initiation R-HSA-69002
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH4 R-HSA-9013694
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RNA Polymerase II Transcription R-HSA-73857
Transport of small molecules R-HSA-382551
Activation of NF-kappaB in B cells R-HSA-1169091
Orc1 removal from chromatin R-HSA-68949
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by ROBO receptors R-HSA-376176
ER-Phagosome pathway R-HSA-1236974
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Signaling by NOTCH R-HSA-157118
Cellular response to chemical stress R-HSA-9711123
Signal Transduction R-HSA-162582
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog 'on' state R-HSA-5632684
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Switching of origins to a post-replicative state R-HSA-69052
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of amino acids and derivatives R-HSA-71291
Host Interactions of HIV factors R-HSA-162909
HIV Infection R-HSA-162906
PCP/CE pathway R-HSA-4086400
Separation of Sister Chromatids R-HSA-2467813
Neddylation R-HSA-8951664
Signaling by NOTCH4 R-HSA-9013694
Vpu mediated degradation of CD4 R-HSA-180534
RNA Polymerase II Transcription R-HSA-73857
Programmed Cell Death R-HSA-5357801
Regulation of expression of SLITs and ROBOs R-HSA-9010553
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Hedgehog R-HSA-5358351
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
UCH proteinases R-HSA-5689603
Orc1 removal from chromatin R-HSA-68949
Ub-specific processing proteases R-HSA-5689880
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent DNA Damage Response R-HSA-69610
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of AXIN R-HSA-4641257
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Regulation of Apoptosis R-HSA-169911
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Apoptosis R-HSA-109581
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX3 R-HSA-8878159
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of mitotic cell cycle R-HSA-453276
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of DVL R-HSA-4641258
ER-Phagosome pathway R-HSA-1236974
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Synthesis of DNA R-HSA-69239
DNA Replication R-HSA-69306
Regulation of RUNX3 expression and activity R-HSA-8941858
Beta-catenin independent WNT signaling R-HSA-3858494
Signal Transduction R-HSA-162582
Metabolism of polyamines R-HSA-351202
Neutrophil degranulation R-HSA-6798695
Asymmetric localization of PCP proteins R-HSA-4608870
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
Regulation of RAS by GAPs R-HSA-5658442
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH R-HSA-157118
Disorders of transmembrane transporters R-HSA-5619115
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular responses to stimuli R-HSA-8953897
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S DNA Damage Checkpoints R-HSA-69615
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular response to hypoxia R-HSA-1234174
Signaling by WNT R-HSA-195721
Assembly of the pre-replicative complex R-HSA-68867
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
p53-Dependent G1 DNA Damage Response R-HSA-69563
Host Interactions of HIV factors R-HSA-162909
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of NF-kappaB in B cells R-HSA-1169091
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism R-HSA-1430728
G1/S Transition R-HSA-69206
M Phase R-HSA-68886
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of beta-catenin by the destruction complex R-HSA-195253
Switching of origins to a post-replicative state R-HSA-69052
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Class I MHC mediated antigen processing & presentation R-HSA-983169
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX1 R-HSA-8878171
ABC transporter disorders R-HSA-5619084
Cellular responses to stress R-HSA-2262752
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle, Mitotic R-HSA-69278
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of GLI1 by the proteasome R-HSA-5610780
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic Metaphase and Anaphase R-HSA-2555396
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of amino acids and derivatives R-HSA-71291
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of proteins R-HSA-392499
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'on' state R-HSA-5632684
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
Axon guidance R-HSA-422475
G2/M Checkpoints R-HSA-69481
Signaling by Interleukins R-HSA-449147
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle R-HSA-1640170
S Phase R-HSA-69242
MAPK family signaling cascades R-HSA-5683057

Expression Atlas ENSG00000106588
NCBI gene (formerly Entrezgene) 5683
GeneCards 9531
HGNC Symbol HGNC:9531
MIM gene 176842
UniProtKB Gene Name P25787
WikiGene 5683
Gene: HTR1D
Ensembl ID : ENSG00000179546
Description: 5-hydroxytryptamine receptor 1D
Gene Synonyms: 5-HT1D,HT1DA,HTRL,RDC4
17 APIs:
67 Possible Orthologues:

Amine ligand-binding receptors R-HSA-375280
Serotonin receptors R-HSA-390666
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Amine ligand-binding receptors R-HSA-375280
Serotonin receptors R-HSA-390666
GPCR ligand binding R-HSA-500792
G alpha (i) signalling events R-HSA-418594
Amine ligand-binding receptors R-HSA-375280
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Serotonin receptors R-HSA-390666
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Amine ligand-binding receptors R-HSA-375280
G alpha (i) signalling events R-HSA-418594
Serotonin receptors R-HSA-390666
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Serotonin receptors R-HSA-390666
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Amine ligand-binding receptors R-HSA-375280
Amine ligand-binding receptors R-HSA-375280
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Serotonin receptors R-HSA-390666
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790

Expression Atlas ENSG00000179546
NCBI gene (formerly Entrezgene) 3352
GeneCards 5289
HGNC Symbol HGNC:5289
MIM gene 182133
UniProtKB Gene Name P28221
WikiGene 3352
Gene: PIK3R3
Ensembl ID : ENSG00000117461
Description: phosphoinositide-3-kinase regulatory subunit 3
Gene Synonyms: P55
26 APIs:
276 Possible Orthologues:

Metabolism of lipids R-HSA-556833
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases R-HSA-194315
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Metabolism R-HSA-1430728
Phospholipid metabolism R-HSA-1483257
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
PI Metabolism R-HSA-1483255
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Axon guidance R-HSA-422475
Platelet activation, signaling and aggregation R-HSA-76002
Interleukin receptor SHC signaling R-HSA-912526
Developmental Biology R-HSA-1266738
PI3K/AKT Signaling in Cancer R-HSA-2219528
Synthesis of PIPs at the plasma membrane R-HSA-1660499
GPCR downstream signalling R-HSA-388396
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAC1 GTPase cycle R-HSA-9013149
PIP3 activates AKT signaling R-HSA-1257604
Signaling by SCF-KIT R-HSA-1433557
G alpha (q) signalling events R-HSA-416476
CD28 co-stimulation R-HSA-389356
Intracellular signaling by second messengers R-HSA-9006925
Interleukin-7 signaling R-HSA-1266695
ESR-mediated signaling R-HSA-8939211
Signaling by GPCR R-HSA-372790
Extra-nuclear estrogen signaling R-HSA-9009391
Immune System R-HSA-168256
Hemostasis R-HSA-109582
Interleukin-2 family signaling R-HSA-451927
GPVI-mediated activation cascade R-HSA-114604
Adaptive Immune System R-HSA-1280218
Negative regulation of the PI3K/AKT network R-HSA-199418
RAC2 GTPase cycle R-HSA-9013404
RHO GTPase cycle R-HSA-9012999
Disease R-HSA-1643685
RET signaling R-HSA-8853659
Costimulation by the CD28 family R-HSA-388841
Regulation of signaling by CBL R-HSA-912631
CD28 dependent PI3K/Akt signaling R-HSA-389357
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by KIT in disease R-HSA-9669938
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Interleukin-2 family signaling R-HSA-451927
Signaling by Rho GTPases R-HSA-194315
ESR-mediated signaling R-HSA-8939211
Developmental Biology R-HSA-1266738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
CD28 co-stimulation R-HSA-389356
Signaling by GPCR R-HSA-372790
Interleukin receptor SHC signaling R-HSA-912526
Metabolism R-HSA-1430728
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G alpha (q) signalling events R-HSA-416476
RAC2 GTPase cycle R-HSA-9013404
Signaling by Nuclear Receptors R-HSA-9006931
GPVI-mediated activation cascade R-HSA-114604
PI Metabolism R-HSA-1483255
Interleukin-7 signaling R-HSA-1266695
GPCR downstream signalling R-HSA-388396
Extra-nuclear estrogen signaling R-HSA-9009391
Nervous system development R-HSA-9675108
Costimulation by the CD28 family R-HSA-388841
Signaling by KIT in disease R-HSA-9669938
Axon guidance R-HSA-422475
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
RHO GTPase cycle R-HSA-9012999
CD28 dependent PI3K/Akt signaling R-HSA-389357
Immune System R-HSA-168256
RET signaling R-HSA-8853659
PI3K/AKT Signaling in Cancer R-HSA-2219528
Hemostasis R-HSA-109582
RAC1 GTPase cycle R-HSA-9013149
Regulation of signaling by CBL R-HSA-912631
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by SCF-KIT R-HSA-1433557
PIP3 activates AKT signaling R-HSA-1257604
Phospholipid metabolism R-HSA-1483257
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Disease R-HSA-1643685
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism of lipids R-HSA-556833
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Phospholipid metabolism R-HSA-1483257
Interleukin-7 signaling R-HSA-1266695
RAC1 GTPase cycle R-HSA-9013149
CD28 dependent PI3K/Akt signaling R-HSA-389357
Disease R-HSA-1643685
GPCR downstream signalling R-HSA-388396
ESR-mediated signaling R-HSA-8939211
Signaling by GPCR R-HSA-372790
PI Metabolism R-HSA-1483255
Costimulation by the CD28 family R-HSA-388841
Signaling by Nuclear Receptors R-HSA-9006931
Axon guidance R-HSA-422475
CD28 co-stimulation R-HSA-389356
Adaptive Immune System R-HSA-1280218
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Interleukins R-HSA-449147
GPVI-mediated activation cascade R-HSA-114604
G alpha (q) signalling events R-HSA-416476
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
Platelet activation, signaling and aggregation R-HSA-76002
Extra-nuclear estrogen signaling R-HSA-9009391
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases R-HSA-194315
Negative regulation of the PI3K/AKT network R-HSA-199418
RHO GTPase cycle R-HSA-9012999
Interleukin receptor SHC signaling R-HSA-912526
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by KIT in disease R-HSA-9669938
Signal Transduction R-HSA-162582
Metabolism of lipids R-HSA-556833
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Hemostasis R-HSA-109582
Regulation of signaling by CBL R-HSA-912631
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Interleukin-2 family signaling R-HSA-451927
RAC2 GTPase cycle R-HSA-9013404
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RET signaling R-HSA-8853659
Signaling by SCF-KIT R-HSA-1433557
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Negative regulation of the PI3K/AKT network R-HSA-199418
Hemostasis R-HSA-109582
CD28 co-stimulation R-HSA-389356
Interleukin receptor SHC signaling R-HSA-912526
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
GPCR downstream signalling R-HSA-388396
Costimulation by the CD28 family R-HSA-388841
Immune System R-HSA-168256
Signaling by Nuclear Receptors R-HSA-9006931
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by SCF-KIT R-HSA-1433557
Signaling by GPCR R-HSA-372790
RHO GTPase cycle R-HSA-9012999
Metabolism R-HSA-1430728
PI3K/AKT Signaling in Cancer R-HSA-2219528
RET signaling R-HSA-8853659
Extra-nuclear estrogen signaling R-HSA-9009391
Platelet activation, signaling and aggregation R-HSA-76002
PI Metabolism R-HSA-1483255
Developmental Biology R-HSA-1266738
Signaling by KIT in disease R-HSA-9669938
Adaptive Immune System R-HSA-1280218
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Phospholipid metabolism R-HSA-1483257
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Rho GTPases R-HSA-194315
Interleukin-2 family signaling R-HSA-451927
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
RAC2 GTPase cycle R-HSA-9013404
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Nervous system development R-HSA-9675108
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Interleukins R-HSA-449147
CD28 dependent PI3K/Akt signaling R-HSA-389357
Interleukin-7 signaling R-HSA-1266695
Axon guidance R-HSA-422475
GPVI-mediated activation cascade R-HSA-114604
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Metabolism of lipids R-HSA-556833
Regulation of signaling by CBL R-HSA-912631
ESR-mediated signaling R-HSA-8939211
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAC1 GTPase cycle R-HSA-9013149
PIP3 activates AKT signaling R-HSA-1257604
Phospholipid metabolism R-HSA-1483257
Signaling by Interleukins R-HSA-449147
ESR-mediated signaling R-HSA-8939211
GPVI-mediated activation cascade R-HSA-114604
Interleukin receptor SHC signaling R-HSA-912526
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Interleukin-2 family signaling R-HSA-451927
GPCR downstream signalling R-HSA-388396
Immune System R-HSA-168256
Signaling by SCF-KIT R-HSA-1433557
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Interleukin-7 signaling R-HSA-1266695
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Hemostasis R-HSA-109582
Negative regulation of the PI3K/AKT network R-HSA-199418
RHO GTPase cycle R-HSA-9012999
CD28 dependent PI3K/Akt signaling R-HSA-389357
Metabolism R-HSA-1430728
Costimulation by the CD28 family R-HSA-388841
Signaling by Rho GTPases R-HSA-194315
Platelet activation, signaling and aggregation R-HSA-76002
PI Metabolism R-HSA-1483255
Signaling by Nuclear Receptors R-HSA-9006931
Intracellular signaling by second messengers R-HSA-9006925
Adaptive Immune System R-HSA-1280218
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by GPCR R-HSA-372790
CD28 co-stimulation R-HSA-389356
G alpha (q) signalling events R-HSA-416476
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
RAC2 GTPase cycle R-HSA-9013404
Developmental Biology R-HSA-1266738
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Signaling by KIT in disease R-HSA-9669938
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RAC1 GTPase cycle R-HSA-9013149
Axon guidance R-HSA-422475
Metabolism of lipids R-HSA-556833
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
RET signaling R-HSA-8853659
PIP3 activates AKT signaling R-HSA-1257604
Regulation of signaling by CBL R-HSA-912631
Extra-nuclear estrogen signaling R-HSA-9009391
PI3K/AKT Signaling in Cancer R-HSA-2219528
Nervous system development R-HSA-9675108
GPCR downstream signalling R-HSA-388396
Extra-nuclear estrogen signaling R-HSA-9009391
Platelet activation, signaling and aggregation R-HSA-76002
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
CD28 dependent PI3K/Akt signaling R-HSA-389357
RHO GTPase cycle R-HSA-9012999
Hemostasis R-HSA-109582
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Metabolism of lipids R-HSA-556833
Disease R-HSA-1643685
RET signaling R-HSA-8853659
Phospholipid metabolism R-HSA-1483257
PI3K/AKT Signaling in Cancer R-HSA-2219528
GPVI-mediated activation cascade R-HSA-114604
PI Metabolism R-HSA-1483255
Adaptive Immune System R-HSA-1280218
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Nervous system development R-HSA-9675108
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAC2 GTPase cycle R-HSA-9013404
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of signaling by CBL R-HSA-912631
Interleukin-2 family signaling R-HSA-451927
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by GPCR R-HSA-372790
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Costimulation by the CD28 family R-HSA-388841
Immune System R-HSA-168256
CD28 co-stimulation R-HSA-389356
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
Negative regulation of the PI3K/AKT network R-HSA-199418
Interleukin receptor SHC signaling R-HSA-912526
Signaling by SCF-KIT R-HSA-1433557
Interleukin-7 signaling R-HSA-1266695
Signaling by Interleukins R-HSA-449147
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
Metabolism R-HSA-1430728
Signaling by KIT in disease R-HSA-9669938
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Rho GTPases R-HSA-194315
ESR-mediated signaling R-HSA-8939211
RAC1 GTPase cycle R-HSA-9013149
Interleukin receptor SHC signaling R-HSA-912526
Synthesis of PIPs at the plasma membrane R-HSA-1660499
RET signaling R-HSA-8853659
Hemostasis R-HSA-109582
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Metabolism of lipids R-HSA-556833
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RHO GTPase cycle R-HSA-9012999
G alpha (q) signalling events R-HSA-416476
Axon guidance R-HSA-422475
Immune System R-HSA-168256
RAC1 GTPase cycle R-HSA-9013149
Signaling by Interleukins R-HSA-449147
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by SCF-KIT R-HSA-1433557
ESR-mediated signaling R-HSA-8939211
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Costimulation by the CD28 family R-HSA-388841
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
CD28 co-stimulation R-HSA-389356
Intracellular signaling by second messengers R-HSA-9006925
Adaptive Immune System R-HSA-1280218
Phospholipid metabolism R-HSA-1483257
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by GPCR R-HSA-372790
Signaling by Rho GTPases R-HSA-194315
Extra-nuclear estrogen signaling R-HSA-9009391
GPCR downstream signalling R-HSA-388396
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Interleukin-2 family signaling R-HSA-451927
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
GPVI-mediated activation cascade R-HSA-114604
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Signaling by KIT in disease R-HSA-9669938
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
PI Metabolism R-HSA-1483255
CD28 dependent PI3K/Akt signaling R-HSA-389357
RAC2 GTPase cycle R-HSA-9013404
Regulation of signaling by CBL R-HSA-912631
Interleukin-7 signaling R-HSA-1266695
Platelet activation, signaling and aggregation R-HSA-76002
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by SCF-KIT R-HSA-1433557
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Immune System R-HSA-168256
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by KIT in disease R-HSA-9669938
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
Costimulation by the CD28 family R-HSA-388841
PI Metabolism R-HSA-1483255
Signaling by GPCR R-HSA-372790
Interleukin-2 family signaling R-HSA-451927
Hemostasis R-HSA-109582
RHO GTPase cycle R-HSA-9012999
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases R-HSA-194315
Extra-nuclear estrogen signaling R-HSA-9009391
Interleukin receptor SHC signaling R-HSA-912526
Regulation of signaling by CBL R-HSA-912631
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
Platelet activation, signaling and aggregation R-HSA-76002
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RAC2 GTPase cycle R-HSA-9013404
PI3K/AKT Signaling in Cancer R-HSA-2219528
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
CD28 co-stimulation R-HSA-389356
RET signaling R-HSA-8853659
G alpha (q) signalling events R-HSA-416476
Signaling by Interleukins R-HSA-449147
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PIP3 activates AKT signaling R-HSA-1257604
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAC1 GTPase cycle R-HSA-9013149
Nervous system development R-HSA-9675108
Phospholipid metabolism R-HSA-1483257
Interleukin-7 signaling R-HSA-1266695
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Developmental Biology R-HSA-1266738
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
GPVI-mediated activation cascade R-HSA-114604
ESR-mediated signaling R-HSA-8939211
Adaptive Immune System R-HSA-1280218
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
GPCR downstream signalling R-HSA-388396
Interleukin-2 family signaling R-HSA-451927
Metabolism of lipids R-HSA-556833
Signaling by KIT in disease R-HSA-9669938
ESR-mediated signaling R-HSA-8939211
Metabolism R-HSA-1430728
Signaling by GPCR R-HSA-372790
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases R-HSA-194315
G alpha (q) signalling events R-HSA-416476
Nervous system development R-HSA-9675108
Costimulation by the CD28 family R-HSA-388841
Phospholipid metabolism R-HSA-1483257
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RAC1 GTPase cycle R-HSA-9013149
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signal Transduction R-HSA-162582
Signaling by SCF-KIT R-HSA-1433557
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Hemostasis R-HSA-109582
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Intracellular signaling by second messengers R-HSA-9006925
GPCR downstream signalling R-HSA-388396
Interleukin receptor SHC signaling R-HSA-912526
Extra-nuclear estrogen signaling R-HSA-9009391
Developmental Biology R-HSA-1266738
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Nuclear Receptors R-HSA-9006931
Regulation of signaling by CBL R-HSA-912631
RAC2 GTPase cycle R-HSA-9013404
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Platelet activation, signaling and aggregation R-HSA-76002
PI Metabolism R-HSA-1483255
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
GPVI-mediated activation cascade R-HSA-114604
RHO GTPase cycle R-HSA-9012999
RET signaling R-HSA-8853659
CD28 co-stimulation R-HSA-389356
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PI3K/AKT Signaling in Cancer R-HSA-2219528
Axon guidance R-HSA-422475
Interleukin-7 signaling R-HSA-1266695
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Rho GTPases R-HSA-194315
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by SCF-KIT R-HSA-1433557
Intracellular signaling by second messengers R-HSA-9006925
RHO GTPase cycle R-HSA-9012999
Signaling by Interleukins R-HSA-449147
Interleukin-2 family signaling R-HSA-451927
Axon guidance R-HSA-422475
PI Metabolism R-HSA-1483255
Signaling by KIT in disease R-HSA-9669938
GPVI-mediated activation cascade R-HSA-114604
Negative regulation of the PI3K/AKT network R-HSA-199418
RAC2 GTPase cycle R-HSA-9013404
G alpha (q) signalling events R-HSA-416476
Immune System R-HSA-168256
Signaling by GPCR R-HSA-372790
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Costimulation by the CD28 family R-HSA-388841
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Nuclear Receptors R-HSA-9006931
Interleukin-7 signaling R-HSA-1266695
Hemostasis R-HSA-109582
ESR-mediated signaling R-HSA-8939211
Adaptive Immune System R-HSA-1280218
GPCR downstream signalling R-HSA-388396
CD28 dependent PI3K/Akt signaling R-HSA-389357
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Cytokine Signaling in Immune system R-HSA-1280215
Developmental Biology R-HSA-1266738
Metabolism R-HSA-1430728
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Extra-nuclear estrogen signaling R-HSA-9009391
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
RET signaling R-HSA-8853659
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Regulation of signaling by CBL R-HSA-912631
PIP3 activates AKT signaling R-HSA-1257604
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism of lipids R-HSA-556833
RAC1 GTPase cycle R-HSA-9013149
Interleukin receptor SHC signaling R-HSA-912526
CD28 co-stimulation R-HSA-389356
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Phospholipid metabolism R-HSA-1483257

Expression Atlas ENSG00000117461
NCBI gene (formerly Entrezgene) 8503
GeneCards 8981
HGNC Symbol HGNC:8981
MIM gene 606076
UniProtKB Gene Name Q92569
WikiGene 8503