Gene: PSMD8
Ensembl ID : ENSG00000099341
Description: proteasome 26S subunit, non-ATPase 8
Gene Synonyms: HIP6,HYPF,NIN1P,P31,RPN12,S14
5 APIs:
200 Possible Orthologues:

Metabolism of proteins R-HSA-392499
M Phase R-HSA-68886
TCR signaling R-HSA-202403
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
UCH proteinases R-HSA-5689603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G1/S DNA Damage Checkpoints R-HSA-69615
Transport of small molecules R-HSA-382551
G1/S Transition R-HSA-69206
Regulation of RAS by GAPs R-HSA-5658442
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic G1 phase and G1/S transition R-HSA-453279
Cytokine Signaling in Immune system R-HSA-1280215
Axon guidance R-HSA-422475
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
Nervous system development R-HSA-9675108
Metabolism R-HSA-1430728
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
ER-Phagosome pathway R-HSA-1236974
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Intracellular signaling by second messengers R-HSA-9006925
S Phase R-HSA-69242
Regulation of PTEN stability and activity R-HSA-8948751
Developmental Biology R-HSA-1266738
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hedgehog 'on' state R-HSA-5632684
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Interleukins R-HSA-449147
Separation of Sister Chromatids R-HSA-2467813
Cellular responses to stress R-HSA-2262752
p53-Independent DNA Damage Response R-HSA-69610
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mitotic cell cycle R-HSA-453276
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Neddylation R-HSA-8951664
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Negative regulation of NOTCH4 signaling R-HSA-9604323
Stabilization of p53 R-HSA-69541
UCH proteinases R-HSA-5689603
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Innate Immune System R-HSA-168249
Cyclin E associated events during G1/S transition R-HSA-69202
TCR signaling R-HSA-202403
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signal Transduction R-HSA-162582
Downstream TCR signaling R-HSA-202424
DNA Replication R-HSA-69306
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of DVL R-HSA-4641258
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic Anaphase R-HSA-68882
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
ABC-family proteins mediated transport R-HSA-382556
TCF dependent signaling in response to WNT R-HSA-201681
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
RNA Polymerase II Transcription R-HSA-73857
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Interleukin-1 signaling R-HSA-9020702
Mitotic G2-G2/M phases R-HSA-453274
PCP/CE pathway R-HSA-4086400
MAPK1/MAPK3 signaling R-HSA-5684996
Antigen processing-Cross presentation R-HSA-1236975
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular response to hypoxia R-HSA-1234174
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Switching of origins to a post-replicative state R-HSA-69052
Signaling by ROBO receptors R-HSA-376176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of RNA R-HSA-8953854
Regulation of RUNX3 expression and activity R-HSA-8941858
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Replication Pre-Initiation R-HSA-69002
G2/M Checkpoints R-HSA-69481
Degradation of GLI2 by the proteasome R-HSA-5610783
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle, Mitotic R-HSA-69278
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Assembly of the pre-replicative complex R-HSA-68867
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
RAF/MAP kinase cascade R-HSA-5673001
Asymmetric localization of PCP proteins R-HSA-4608870
Gene expression (Transcription) R-HSA-74160
PTEN Regulation R-HSA-6807070
Signaling by Hedgehog R-HSA-5358351
Adaptive Immune System R-HSA-1280218
Orc1 removal from chromatin R-HSA-68949
HIV Infection R-HSA-162906
C-type lectin receptors (CLRs) R-HSA-5621481
Interleukin-1 family signaling R-HSA-446652
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Disorders of transmembrane transporters R-HSA-5619115
Apoptosis R-HSA-109581
Infectious disease R-HSA-5663205
M Phase R-HSA-68886
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of AXIN R-HSA-4641257
MAPK family signaling cascades R-HSA-5683057
Signaling by WNT R-HSA-195721
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Class I MHC mediated antigen processing & presentation R-HSA-983169
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH R-HSA-157118
Regulation of RUNX2 expression and activity R-HSA-8939902
Synthesis of DNA R-HSA-69239
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
Ub-specific processing proteases R-HSA-5689880
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Defective CFTR causes cystic fibrosis R-HSA-5678895
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of Apoptosis R-HSA-169911
ABC transporter disorders R-HSA-5619084
Cell Cycle R-HSA-1640170
Cellular responses to stimuli R-HSA-8953897
Cell Cycle Checkpoints R-HSA-69620
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Generic Transcription Pathway R-HSA-212436
Programmed Cell Death R-HSA-5357801
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
G2/M Transition R-HSA-69275
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Antigen processing-Cross presentation R-HSA-1236975
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
G1/S Transition R-HSA-69206
Switching of origins to a post-replicative state R-HSA-69052
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Programmed Cell Death R-HSA-5357801
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Generic Transcription Pathway R-HSA-212436
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PTEN Regulation R-HSA-6807070
Mitotic G1 phase and G1/S transition R-HSA-453279
Cyclin E associated events during G1/S transition R-HSA-69202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Intracellular signaling by second messengers R-HSA-9006925
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
DNA Replication R-HSA-69306
Separation of Sister Chromatids R-HSA-2467813
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by WNT R-HSA-195721
RNA Polymerase II Transcription R-HSA-73857
Orc1 removal from chromatin R-HSA-68949
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Anaphase R-HSA-68882
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
S Phase R-HSA-69242
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of AXIN R-HSA-4641257
G1/S DNA Damage Checkpoints R-HSA-69615
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cytokine Signaling in Immune system R-HSA-1280215
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream TCR signaling R-HSA-202424
Cell Cycle, Mitotic R-HSA-69278
Cellular response to hypoxia R-HSA-1234174
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by Hedgehog R-HSA-5358351
Vpu mediated degradation of CD4 R-HSA-180534
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle R-HSA-1640170
Hedgehog ligand biogenesis R-HSA-5358346
C-type lectin receptors (CLRs) R-HSA-5621481
Asymmetric localization of PCP proteins R-HSA-4608870
Developmental Biology R-HSA-1266738
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Synthesis of DNA R-HSA-69239
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle Checkpoints R-HSA-69620
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Dependent G1 DNA Damage Response R-HSA-69563
Infectious disease R-HSA-5663205
Class I MHC mediated antigen processing & presentation R-HSA-983169
Beta-catenin independent WNT signaling R-HSA-3858494
Stabilization of p53 R-HSA-69541
Metabolism of amino acids and derivatives R-HSA-71291
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of DVL R-HSA-4641258
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of RUNX3 expression and activity R-HSA-8941858
Hh mutants are degraded by ERAD R-HSA-5362768
Host Interactions of HIV factors R-HSA-162909
PIP3 activates AKT signaling R-HSA-1257604
DNA Replication Pre-Initiation R-HSA-69002
PCP/CE pathway R-HSA-4086400
Disorders of transmembrane transporters R-HSA-5619115
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by NOTCH R-HSA-157118
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
TCR signaling R-HSA-202403
Interleukin-1 signaling R-HSA-9020702
Metabolism of polyamines R-HSA-351202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of GLI2 by the proteasome R-HSA-5610783
MAPK6/MAPK4 signaling R-HSA-5687128
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of Apoptosis R-HSA-169911
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular response to chemical stress R-HSA-9711123
Immune System R-HSA-168256
UCH proteinases R-HSA-5689603
Transport of small molecules R-HSA-382551
Signaling by Interleukins R-HSA-449147
Hedgehog 'off' state R-HSA-5610787
Ub-specific processing proteases R-HSA-5689880
HIV Infection R-HSA-162906
Neddylation R-HSA-8951664
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Assembly of the pre-replicative complex R-HSA-68867
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Apoptosis R-HSA-109581
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Innate Immune System R-HSA-168249
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Checkpoints R-HSA-69481
Regulation of RAS by GAPs R-HSA-5658442
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC-family proteins mediated transport R-HSA-382556
Mitotic G2-G2/M phases R-HSA-453274
Transcriptional regulation by RUNX3 R-HSA-8878159
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular responses to stimuli R-HSA-8953897
Signaling by ROBO receptors R-HSA-376176
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular responses to stress R-HSA-2262752
Regulation of mitotic cell cycle R-HSA-453276
FCERI mediated NF-kB activation R-HSA-2871837
Deubiquitination R-HSA-5688426
Metabolism R-HSA-1430728
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'on' state R-HSA-5632684
p53-Independent DNA Damage Response R-HSA-69610
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of RAS by GAPs R-HSA-5658442
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'on' state R-HSA-5632684
M Phase R-HSA-68886
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI2 by the proteasome R-HSA-5610783
DNA Replication R-HSA-69306
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transport of small molecules R-HSA-382551
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by ROBO receptors R-HSA-376176
Cell Cycle, Mitotic R-HSA-69278
Programmed Cell Death R-HSA-5357801
Negative regulation of NOTCH4 signaling R-HSA-9604323
UCH proteinases R-HSA-5689603
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing-Cross presentation R-HSA-1236975
Innate Immune System R-HSA-168249
Interleukin-1 family signaling R-HSA-446652
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of GLI1 by the proteasome R-HSA-5610780
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
MAPK6/MAPK4 signaling R-HSA-5687128
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by WNT R-HSA-195721
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream TCR signaling R-HSA-202424
MAPK family signaling cascades R-HSA-5683057
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ABC-family proteins mediated transport R-HSA-382556
Signaling by NOTCH4 R-HSA-9013694
Orc1 removal from chromatin R-HSA-68949
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
Adaptive Immune System R-HSA-1280218
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of polyamines R-HSA-351202
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of NF-kappaB in B cells R-HSA-1169091
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of DVL R-HSA-4641258
Signaling by Hedgehog R-HSA-5358351
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional regulation by RUNX1 R-HSA-8878171
HIV Infection R-HSA-162906
Post-translational protein modification R-HSA-597592
Signaling by NOTCH R-HSA-157118
Hedgehog ligand biogenesis R-HSA-5358346
Nuclear events mediated by NFE2L2 R-HSA-9759194
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of proteins R-HSA-392499
PCP/CE pathway R-HSA-4086400
Generic Transcription Pathway R-HSA-212436
Intracellular signaling by second messengers R-HSA-9006925
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of Apoptosis R-HSA-169911
Metabolism of amino acids and derivatives R-HSA-71291
Asymmetric localization of PCP proteins R-HSA-4608870
FCERI mediated NF-kB activation R-HSA-2871837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent DNA Damage Response R-HSA-69610
S Phase R-HSA-69242
Apoptosis R-HSA-109581
Infectious disease R-HSA-5663205
Ub-specific processing proteases R-HSA-5689880
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Host Interactions of HIV factors R-HSA-162909
Synthesis of DNA R-HSA-69239
Switching of origins to a post-replicative state R-HSA-69052
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signal Transduction R-HSA-162582
Hh mutants abrogate ligand secretion R-HSA-5387390
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Interleukin-1 signaling R-HSA-9020702
Cytokine Signaling in Immune system R-HSA-1280215
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle Checkpoints R-HSA-69620
ABC transporter disorders R-HSA-5619084
ER-Phagosome pathway R-HSA-1236974
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic Anaphase R-HSA-68882
Degradation of AXIN R-HSA-4641257
Separation of Sister Chromatids R-HSA-2467813
Cellular responses to stress R-HSA-2262752
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
DNA Replication Pre-Initiation R-HSA-69002
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Disorders of transmembrane transporters R-HSA-5619115
Gene expression (Transcription) R-HSA-74160
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic Metaphase and Anaphase R-HSA-2555396
Stabilization of p53 R-HSA-69541
Disease R-HSA-1643685
Class I MHC mediated antigen processing & presentation R-HSA-983169
G1/S Transition R-HSA-69206
Signaling by Interleukins R-HSA-449147
Regulation of RUNX2 expression and activity R-HSA-8939902
Assembly of the pre-replicative complex R-HSA-68867
Beta-catenin independent WNT signaling R-HSA-3858494
KEAP1-NFE2L2 pathway R-HSA-9755511
Developmental Biology R-HSA-1266738
Hedgehog 'off' state R-HSA-5610787
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle R-HSA-1640170
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TCR signaling R-HSA-202403
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S DNA Damage Checkpoints R-HSA-69615
Immune System R-HSA-168256
Mitotic G2-G2/M phases R-HSA-453274
G2/M Checkpoints R-HSA-69481
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
Axon guidance R-HSA-422475
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Neddylation R-HSA-8951664
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK1/MAPK3 signaling R-HSA-5684996
ER-Phagosome pathway R-HSA-1236974
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
FCERI mediated NF-kB activation R-HSA-2871837
Nervous system development R-HSA-9675108
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of PTEN stability and activity R-HSA-8948751
Beta-catenin independent WNT signaling R-HSA-3858494
RAF/MAP kinase cascade R-HSA-5673001
Programmed Cell Death R-HSA-5357801
Class I MHC mediated antigen processing & presentation R-HSA-983169
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
Degradation of GLI2 by the proteasome R-HSA-5610783
Mitotic Anaphase R-HSA-68882
Metabolism of RNA R-HSA-8953854
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle Checkpoints R-HSA-69620
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of DVL R-HSA-4641258
Cellular response to hypoxia R-HSA-1234174
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
KEAP1-NFE2L2 pathway R-HSA-9755511
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Innate Immune System R-HSA-168249
Asymmetric localization of PCP proteins R-HSA-4608870
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of Apoptosis R-HSA-169911
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
HIV Infection R-HSA-162906
Interleukin-1 signaling R-HSA-9020702
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by Interleukins R-HSA-449147
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RAS by GAPs R-HSA-5658442
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G2-G2/M phases R-HSA-453274
Signaling by WNT R-HSA-195721
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PTEN Regulation R-HSA-6807070
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'off' state R-HSA-5610787
Infectious disease R-HSA-5663205
Immune System R-HSA-168256
Signaling by ROBO receptors R-HSA-376176
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by the B Cell Receptor (BCR) R-HSA-983705
DNA Replication R-HSA-69306
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Activation of NF-kappaB in B cells R-HSA-1169091
ABC transporter disorders R-HSA-5619084
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX2 R-HSA-8878166
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of RUNX3 expression and activity R-HSA-8941858
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of GLI1 by the proteasome R-HSA-5610780
Ub-specific processing proteases R-HSA-5689880
Adaptive Immune System R-HSA-1280218
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Switching of origins to a post-replicative state R-HSA-69052
TCR signaling R-HSA-202403
G2/M Checkpoints R-HSA-69481
Disorders of transmembrane transporters R-HSA-5619115
Metabolism R-HSA-1430728
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'on' state R-HSA-5632684
Signaling by Hedgehog R-HSA-5358351
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of AXIN R-HSA-4641257
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cellular response to chemical stress R-HSA-9711123
Orc1 removal from chromatin R-HSA-68949
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of polyamines R-HSA-351202
Stabilization of p53 R-HSA-69541
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by NOTCH4 R-HSA-9013694
S Phase R-HSA-69242
Transcriptional regulation by RUNX3 R-HSA-8878159
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of mitotic cell cycle R-HSA-453276
Assembly of the pre-replicative complex R-HSA-68867
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of amino acids and derivatives R-HSA-71291
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
C-type lectin receptors (CLRs) R-HSA-5621481
Synthesis of DNA R-HSA-69239
Separation of Sister Chromatids R-HSA-2467813
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Deubiquitination R-HSA-5688426
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S Transition R-HSA-69206
ABC-family proteins mediated transport R-HSA-382556
Apoptosis R-HSA-109581
Interleukin-1 family signaling R-HSA-446652
Post-translational protein modification R-HSA-597592
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent DNA Damage Response R-HSA-69610
Downstream TCR signaling R-HSA-202424
p53-Dependent G1 DNA Damage Response R-HSA-69563
Host Interactions of HIV factors R-HSA-162909
Neddylation R-HSA-8951664
Signaling by NOTCH R-HSA-157118
Cellular responses to stress R-HSA-2262752
Intracellular signaling by second messengers R-HSA-9006925
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
M Phase R-HSA-68886
G2/M Transition R-HSA-69275
TCF dependent signaling in response to WNT R-HSA-201681
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CLEC7A (Dectin-1) signaling R-HSA-5607764
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cell Cycle R-HSA-1640170
p53-Independent DNA Damage Response R-HSA-69610
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
KEAP1-NFE2L2 pathway R-HSA-9755511
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
ABC-family proteins mediated transport R-HSA-382556
Mitotic G2-G2/M phases R-HSA-453274
HIV Infection R-HSA-162906
MAPK family signaling cascades R-HSA-5683057
Interleukin-1 family signaling R-HSA-446652
Synthesis of DNA R-HSA-69239
DNA Replication R-HSA-69306
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
Cellular responses to stress R-HSA-2262752
Deubiquitination R-HSA-5688426
Signaling by NOTCH4 R-HSA-9013694
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX2 R-HSA-8878166
Axon guidance R-HSA-422475
Mitotic Anaphase R-HSA-68882
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Disorders of transmembrane transporters R-HSA-5619115
Cellular response to chemical stress R-HSA-9711123
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CLEC7A (Dectin-1) signaling R-HSA-5607764
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Cellular response to hypoxia R-HSA-1234174
Antigen processing-Cross presentation R-HSA-1236975
Signaling by Interleukins R-HSA-449147
RNA Polymerase II Transcription R-HSA-73857
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism of RNA R-HSA-8953854
Signal Transduction R-HSA-162582
Downstream TCR signaling R-HSA-202424
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Orc1 removal from chromatin R-HSA-68949
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Programmed Cell Death R-HSA-5357801
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PCP/CE pathway R-HSA-4086400
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Post-translational protein modification R-HSA-597592
Hh mutants are degraded by ERAD R-HSA-5362768
Neddylation R-HSA-8951664
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Checkpoints R-HSA-69481
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
Signaling by NOTCH R-HSA-157118
Cyclin E associated events during G1/S transition R-HSA-69202
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
Regulation of RUNX3 expression and activity R-HSA-8941858
Class I MHC mediated antigen processing & presentation R-HSA-983169
Switching of origins to a post-replicative state R-HSA-69052
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of DVL R-HSA-4641258
Regulation of RAS by GAPs R-HSA-5658442
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX1 R-HSA-8878171
PTEN Regulation R-HSA-6807070
ABC transporter disorders R-HSA-5619084
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of Apoptosis R-HSA-169911
Signaling by Hedgehog R-HSA-5358351
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Ub-specific processing proteases R-HSA-5689880
Asymmetric localization of PCP proteins R-HSA-4608870
Hh mutants abrogate ligand secretion R-HSA-5387390
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'off' state R-HSA-5610787
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Host Interactions of HIV factors R-HSA-162909
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mitotic cell cycle R-HSA-453276
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle, Mitotic R-HSA-69278
M Phase R-HSA-68886
Signaling by WNT R-HSA-195721
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Developmental Biology R-HSA-1266738
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Transition R-HSA-69275
RAF/MAP kinase cascade R-HSA-5673001
Infectious disease R-HSA-5663205
Metabolism of polyamines R-HSA-351202
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RUNX2 expression and activity R-HSA-8939902
Gene expression (Transcription) R-HSA-74160
Hedgehog ligand biogenesis R-HSA-5358346
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of AXIN R-HSA-4641257
Cellular responses to stimuli R-HSA-8953897
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Metaphase and Anaphase R-HSA-2555396
Separation of Sister Chromatids R-HSA-2467813
p53-Dependent G1 DNA Damage Response R-HSA-69563
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 signaling R-HSA-9020702
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
S Phase R-HSA-69242
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of proteins R-HSA-392499
Assembly of the pre-replicative complex R-HSA-68867
Immune System R-HSA-168256
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cytokine Signaling in Immune system R-HSA-1280215
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by ROBO receptors R-HSA-376176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
CLEC7A (Dectin-1) signaling R-HSA-5607764
Defective CFTR causes cystic fibrosis R-HSA-5678895
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ABC-family proteins mediated transport R-HSA-382556
p53-Dependent G1 DNA Damage Response R-HSA-69563
Immune System R-HSA-168256
Cell Cycle R-HSA-1640170
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by Hedgehog R-HSA-5358351
Cytokine Signaling in Immune system R-HSA-1280215
Vpu mediated degradation of CD4 R-HSA-180534
DNA Replication Pre-Initiation R-HSA-69002
Regulation of mitotic cell cycle R-HSA-453276
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Synthesis of DNA R-HSA-69239
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
p53-Independent DNA Damage Response R-HSA-69610
Infectious disease R-HSA-5663205
Asymmetric localization of PCP proteins R-HSA-4608870
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
TCF dependent signaling in response to WNT R-HSA-201681
Programmed Cell Death R-HSA-5357801
Adaptive Immune System R-HSA-1280218
RAF/MAP kinase cascade R-HSA-5673001
Activation of NF-kappaB in B cells R-HSA-1169091
Stabilization of p53 R-HSA-69541
Nervous system development R-HSA-9675108
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Class I MHC mediated antigen processing & presentation R-HSA-983169
Switching of origins to a post-replicative state R-HSA-69052
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Post-translational protein modification R-HSA-597592
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Innate Immune System R-HSA-168249
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular response to hypoxia R-HSA-1234174
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G2/M Checkpoints R-HSA-69481
TCR signaling R-HSA-202403
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Assembly of the pre-replicative complex R-HSA-68867
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX1 R-HSA-8878171
Intracellular signaling by second messengers R-HSA-9006925
Signaling by WNT R-HSA-195721
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI2 by the proteasome R-HSA-5610783
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog ligand biogenesis R-HSA-5358346
ER-Phagosome pathway R-HSA-1236974
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Developmental Biology R-HSA-1266738
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
Cell Cycle Checkpoints R-HSA-69620
Deubiquitination R-HSA-5688426
Metabolism R-HSA-1430728
Degradation of GLI1 by the proteasome R-HSA-5610780
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH4 R-HSA-9013694
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Mitotic G2-G2/M phases R-HSA-453274
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular responses to stimuli R-HSA-8953897
Antigen processing-Cross presentation R-HSA-1236975
HIV Infection R-HSA-162906
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 family signaling R-HSA-446652
Downstream TCR signaling R-HSA-202424
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Metabolism of amino acids and derivatives R-HSA-71291
Apoptosis R-HSA-109581
PIP3 activates AKT signaling R-HSA-1257604
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Host Interactions of HIV factors R-HSA-162909
UCH proteinases R-HSA-5689603
Metabolism of proteins R-HSA-392499
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of DVL R-HSA-4641258
G2/M Transition R-HSA-69275
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
S Phase R-HSA-69242
Hedgehog 'on' state R-HSA-5632684
Regulation of RUNX2 expression and activity R-HSA-8939902
ABC transporter disorders R-HSA-5619084
G1/S DNA Damage Checkpoints R-HSA-69615
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX3 R-HSA-8878159
MAPK1/MAPK3 signaling R-HSA-5684996
DNA Replication R-HSA-69306
Separation of Sister Chromatids R-HSA-2467813
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle, Mitotic R-HSA-69278
M Phase R-HSA-68886
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RAS by GAPs R-HSA-5658442
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Axon guidance R-HSA-422475
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FCERI mediated NF-kB activation R-HSA-2871837
Orc1 removal from chromatin R-HSA-68949
Signaling by NOTCH R-HSA-157118
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of Apoptosis R-HSA-169911
Hedgehog 'off' state R-HSA-5610787
Disorders of transmembrane transporters R-HSA-5619115
RNA Polymerase II Transcription R-HSA-73857
PCP/CE pathway R-HSA-4086400
Metabolism of polyamines R-HSA-351202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G1/S Transition R-HSA-69206
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK family signaling cascades R-HSA-5683057
Signaling by Interleukins R-HSA-449147
Interleukin-1 signaling R-HSA-9020702
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ub-specific processing proteases R-HSA-5689880
Mitotic Metaphase and Anaphase R-HSA-2555396
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
Degradation of beta-catenin by the destruction complex R-HSA-195253
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
G1/S Transition R-HSA-69206
Infectious disease R-HSA-5663205
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of proteins R-HSA-392499
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mitotic cell cycle R-HSA-453276
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular response to hypoxia R-HSA-1234174
RNA Polymerase II Transcription R-HSA-73857
Programmed Cell Death R-HSA-5357801
M Phase R-HSA-68886
Separation of Sister Chromatids R-HSA-2467813
Degradation of GLI2 by the proteasome R-HSA-5610783
Transcriptional regulation by RUNX1 R-HSA-8878171
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
Regulation of RAS by GAPs R-HSA-5658442
Axon guidance R-HSA-422475
Cell Cycle Checkpoints R-HSA-69620
FCERI mediated NF-kB activation R-HSA-2871837
Neddylation R-HSA-8951664
Regulation of PTEN stability and activity R-HSA-8948751
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX3 R-HSA-8878159
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vpu mediated degradation of CD4 R-HSA-180534
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle R-HSA-1640170
Mitotic G1 phase and G1/S transition R-HSA-453279
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Host Interactions of HIV factors R-HSA-162909
Intracellular signaling by second messengers R-HSA-9006925
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic Anaphase R-HSA-68882
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Metaphase and Anaphase R-HSA-2555396
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of beta-catenin by the destruction complex R-HSA-195253
Interleukin-1 signaling R-HSA-9020702
S Phase R-HSA-69242
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream TCR signaling R-HSA-202424
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Stabilization of p53 R-HSA-69541
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of RUNX2 expression and activity R-HSA-8939902
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Vif-mediated degradation of APOBEC3G R-HSA-180585
Post-translational protein modification R-HSA-597592
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK family signaling cascades R-HSA-5683057
Mitotic G2-G2/M phases R-HSA-453274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH R-HSA-157118
Immune System R-HSA-168256
Disorders of transmembrane transporters R-HSA-5619115
UCH proteinases R-HSA-5689603
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Apoptosis R-HSA-109581
Regulation of Apoptosis R-HSA-169911
DNA Replication R-HSA-69306
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of AXIN R-HSA-4641257
Nervous system development R-HSA-9675108
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by ROBO receptors R-HSA-376176
Deubiquitination R-HSA-5688426
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 family signaling R-HSA-446652
Synthesis of DNA R-HSA-69239
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog ligand biogenesis R-HSA-5358346
Cellular responses to stimuli R-HSA-8953897
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular responses to stress R-HSA-2262752
Regulation of expression of SLITs and ROBOs R-HSA-9010553
ABC transporter disorders R-HSA-5619084
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by NOTCH4 R-HSA-9013694
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of DVL R-HSA-4641258
MAPK6/MAPK4 signaling R-HSA-5687128
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism R-HSA-1430728
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
Antigen processing-Cross presentation R-HSA-1236975
ER-Phagosome pathway R-HSA-1236974
RAF/MAP kinase cascade R-HSA-5673001
Innate Immune System R-HSA-168249
Metabolism of RNA R-HSA-8953854
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ub-specific processing proteases R-HSA-5689880
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Adaptive Immune System R-HSA-1280218
Cyclin E associated events during G1/S transition R-HSA-69202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to chemical stress R-HSA-9711123
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Switching of origins to a post-replicative state R-HSA-69052
Gene expression (Transcription) R-HSA-74160
Transport of small molecules R-HSA-382551
Signaling by WNT R-HSA-195721
Hedgehog 'on' state R-HSA-5632684
PTEN Regulation R-HSA-6807070
Activation of NF-kappaB in B cells R-HSA-1169091
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signal Transduction R-HSA-162582
HIV Infection R-HSA-162906
Assembly of the pre-replicative complex R-HSA-68867
Signaling by Interleukins R-HSA-449147
PCP/CE pathway R-HSA-4086400
Asymmetric localization of PCP proteins R-HSA-4608870
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
ABC-family proteins mediated transport R-HSA-382556
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of polyamines R-HSA-351202
Cell Cycle, Mitotic R-HSA-69278
C-type lectin receptors (CLRs) R-HSA-5621481
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hh mutants abrogate ligand secretion R-HSA-5387390
TCR signaling R-HSA-202403
Hedgehog 'off' state R-HSA-5610787
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G1/S DNA Damage Checkpoints R-HSA-69615
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hh mutants are degraded by ERAD R-HSA-5362768
Cytokine Signaling in Immune system R-HSA-1280215
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Independent DNA Damage Response R-HSA-69610
Disease R-HSA-1643685
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular response to hypoxia R-HSA-1234174
Signaling by ROBO receptors R-HSA-376176
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ER-Phagosome pathway R-HSA-1236974
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Stabilization of p53 R-HSA-69541
Degradation of GLI2 by the proteasome R-HSA-5610783
Host Interactions of HIV factors R-HSA-162909
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular response to chemical stress R-HSA-9711123
Immune System R-HSA-168256
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Separation of Sister Chromatids R-HSA-2467813
Hh mutants abrogate ligand secretion R-HSA-5387390
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of RUNX2 expression and activity R-HSA-8939902
Synthesis of DNA R-HSA-69239
Orc1 removal from chromatin R-HSA-68949
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
KEAP1-NFE2L2 pathway R-HSA-9755511
Axon guidance R-HSA-422475
Metabolism of amino acids and derivatives R-HSA-71291
Generic Transcription Pathway R-HSA-212436
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic G2-G2/M phases R-HSA-453274
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
PIP3 activates AKT signaling R-HSA-1257604
Switching of origins to a post-replicative state R-HSA-69052
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
Infectious disease R-HSA-5663205
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by NOTCH4 R-HSA-9013694
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle Checkpoints R-HSA-69620
Hedgehog 'on' state R-HSA-5632684
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Nuclear events mediated by NFE2L2 R-HSA-9759194
Disease R-HSA-1643685
TCR signaling R-HSA-202403
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
S Phase R-HSA-69242
Gene expression (Transcription) R-HSA-74160
FCERI mediated NF-kB activation R-HSA-2871837
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Nervous system development R-HSA-9675108
Metabolism of polyamines R-HSA-351202
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
PCP/CE pathway R-HSA-4086400
ABC transporter disorders R-HSA-5619084
Cellular responses to stimuli R-HSA-8953897
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mitotic cell cycle R-HSA-453276
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants are degraded by ERAD R-HSA-5362768
Signal Transduction R-HSA-162582
Degradation of AXIN R-HSA-4641257
Mitotic Anaphase R-HSA-68882
Antigen processing-Cross presentation R-HSA-1236975
Downstream TCR signaling R-HSA-202424
C-type lectin receptors (CLRs) R-HSA-5621481
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Innate Immune System R-HSA-168249
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Asymmetric localization of PCP proteins R-HSA-4608870
Mitotic G1 phase and G1/S transition R-HSA-453279
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of Apoptosis R-HSA-169911
Neddylation R-HSA-8951664
TCF dependent signaling in response to WNT R-HSA-201681
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
UCH proteinases R-HSA-5689603
Vpu mediated degradation of CD4 R-HSA-180534
Transport of small molecules R-HSA-382551
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stress R-HSA-2262752
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of proteins R-HSA-392499
Degradation of DVL R-HSA-4641258
Post-translational protein modification R-HSA-597592
Signaling by Hedgehog R-HSA-5358351
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Intracellular signaling by second messengers R-HSA-9006925
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by Interleukins R-HSA-449147
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cytokine Signaling in Immune system R-HSA-1280215
Ub-specific processing proteases R-HSA-5689880
Transcriptional regulation by RUNX2 R-HSA-8878166
Deubiquitination R-HSA-5688426
DNA Replication R-HSA-69306
p53-Independent DNA Damage Response R-HSA-69610
HIV Infection R-HSA-162906
Class I MHC mediated antigen processing & presentation R-HSA-983169
Assembly of the pre-replicative complex R-HSA-68867
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cell Cycle R-HSA-1640170
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC-family proteins mediated transport R-HSA-382556
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hedgehog 'off' state R-HSA-5610787
Degradation of GLI1 by the proteasome R-HSA-5610780
CLEC7A (Dectin-1) signaling R-HSA-5607764
G2/M Transition R-HSA-69275
Developmental Biology R-HSA-1266738
Metabolism of RNA R-HSA-8953854
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
M Phase R-HSA-68886
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 signaling R-HSA-9020702
G1/S Transition R-HSA-69206
Disorders of transmembrane transporters R-HSA-5619115
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by WNT R-HSA-195721
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
PTEN Regulation R-HSA-6807070
Signaling by NOTCH R-HSA-157118
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of polyamines R-HSA-351202
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Disease R-HSA-1643685
Transcriptional regulation by RUNX2 R-HSA-8878166
Separation of Sister Chromatids R-HSA-2467813
Adaptive Immune System R-HSA-1280218
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic Metaphase and Anaphase R-HSA-2555396
Nuclear events mediated by NFE2L2 R-HSA-9759194
Host Interactions of HIV factors R-HSA-162909
HIV Infection R-HSA-162906
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RUNX2 expression and activity R-HSA-8939902
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by WNT R-HSA-195721
Hh mutants are degraded by ERAD R-HSA-5362768
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular responses to stress R-HSA-2262752
MAPK6/MAPK4 signaling R-HSA-5687128
TCF dependent signaling in response to WNT R-HSA-201681
Downstream TCR signaling R-HSA-202424
G2/M Transition R-HSA-69275
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by NOTCH R-HSA-157118
Mitotic G2-G2/M phases R-HSA-453274
Metabolism of RNA R-HSA-8953854
Signal Transduction R-HSA-162582
PCP/CE pathway R-HSA-4086400
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Hedgehog R-HSA-5358351
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Interleukin-1 signaling R-HSA-9020702
Cell Cycle Checkpoints R-HSA-69620
Deubiquitination R-HSA-5688426
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle, Mitotic R-HSA-69278
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of PTEN stability and activity R-HSA-8948751
Generic Transcription Pathway R-HSA-212436
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX3 expression and activity R-HSA-8941858
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
RAF/MAP kinase cascade R-HSA-5673001
M Phase R-HSA-68886
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
C-type lectin receptors (CLRs) R-HSA-5621481
Beta-catenin independent WNT signaling R-HSA-3858494
Synthesis of DNA R-HSA-69239
Ub-specific processing proteases R-HSA-5689880
G1/S Transition R-HSA-69206
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Apoptosis R-HSA-109581
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Metabolism of proteins R-HSA-392499
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Stabilization of p53 R-HSA-69541
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Class I MHC mediated antigen processing & presentation R-HSA-983169
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog 'off' state R-HSA-5610787
Interleukin-1 family signaling R-HSA-446652
Vif-mediated degradation of APOBEC3G R-HSA-180585
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of NF-kappaB in B cells R-HSA-1169091
Disorders of transmembrane transporters R-HSA-5619115
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ABC transporter disorders R-HSA-5619084
Degradation of DVL R-HSA-4641258
Transcriptional regulation by RUNX3 R-HSA-8878159
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RAS by GAPs R-HSA-5658442
Antigen processing-Cross presentation R-HSA-1236975
TCR signaling R-HSA-202403
S Phase R-HSA-69242
MAPK family signaling cascades R-HSA-5683057
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Transport of small molecules R-HSA-382551
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G2/M Checkpoints R-HSA-69481
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
PIP3 activates AKT signaling R-HSA-1257604
Signaling by ROBO receptors R-HSA-376176
p53-Independent DNA Damage Response R-HSA-69610
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular response to chemical stress R-HSA-9711123
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to hypoxia R-HSA-1234174
ABC-family proteins mediated transport R-HSA-382556
Innate Immune System R-HSA-168249
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
FCERI mediated NF-kB activation R-HSA-2871837
Hedgehog 'on' state R-HSA-5632684
ER-Phagosome pathway R-HSA-1236974
Developmental Biology R-HSA-1266738
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of AXIN R-HSA-4641257
Infectious disease R-HSA-5663205
Intracellular signaling by second messengers R-HSA-9006925
Vpu mediated degradation of CD4 R-HSA-180534
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cyclin E associated events during G1/S transition R-HSA-69202
UCH proteinases R-HSA-5689603
Cytokine Signaling in Immune system R-HSA-1280215
Neddylation R-HSA-8951664
Programmed Cell Death R-HSA-5357801
PTEN Regulation R-HSA-6807070
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Orc1 removal from chromatin R-HSA-68949
Assembly of the pre-replicative complex R-HSA-68867
Post-translational protein modification R-HSA-597592
G1/S DNA Damage Checkpoints R-HSA-69615
Gene expression (Transcription) R-HSA-74160
Regulation of Apoptosis R-HSA-169911
Metabolism R-HSA-1430728
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
DNA Replication Pre-Initiation R-HSA-69002
DNA Replication R-HSA-69306
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Anaphase R-HSA-68882
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mitotic cell cycle R-HSA-453276
Signaling by NOTCH4 R-HSA-9013694
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Axon guidance R-HSA-422475
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stimuli R-HSA-8953897
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Orc1 removal from chromatin R-HSA-68949
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
UCH proteinases R-HSA-5689603
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hh mutants abrogate ligand secretion R-HSA-5387390
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transport of small molecules R-HSA-382551
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by Hedgehog R-HSA-5358351
Mitotic G1 phase and G1/S transition R-HSA-453279
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Assembly of the pre-replicative complex R-HSA-68867
Innate Immune System R-HSA-168249
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
PTEN Regulation R-HSA-6807070
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to chemical stress R-HSA-9711123
Stabilization of p53 R-HSA-69541
Signal Transduction R-HSA-162582
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stress R-HSA-2262752
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by Interleukins R-HSA-449147
DNA Replication R-HSA-69306
Immune System R-HSA-168256
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
HIV Infection R-HSA-162906
Vpu mediated degradation of CD4 R-HSA-180534
ER-Phagosome pathway R-HSA-1236974
MAPK1/MAPK3 signaling R-HSA-5684996
Adaptive Immune System R-HSA-1280218
MAPK6/MAPK4 signaling R-HSA-5687128
Disease R-HSA-1643685
G1/S DNA Damage Checkpoints R-HSA-69615
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism R-HSA-1430728
Separation of Sister Chromatids R-HSA-2467813
PCP/CE pathway R-HSA-4086400
G1/S Transition R-HSA-69206
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX1 R-HSA-8878171
Developmental Biology R-HSA-1266738
Mitotic Anaphase R-HSA-68882
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of proteins R-HSA-392499
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Disorders of transmembrane transporters R-HSA-5619115
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of Apoptosis R-HSA-169911
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
DNA Replication Pre-Initiation R-HSA-69002
M Phase R-HSA-68886
Metabolism of polyamines R-HSA-351202
Deubiquitination R-HSA-5688426
Cell Cycle, Mitotic R-HSA-69278
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 signaling R-HSA-9020702
CLEC7A (Dectin-1) signaling R-HSA-5607764
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TCF dependent signaling in response to WNT R-HSA-201681
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of RNA R-HSA-8953854
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by NOTCH R-HSA-157118
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Antigen processing-Cross presentation R-HSA-1236975
Axon guidance R-HSA-422475
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of DVL R-HSA-4641258
p53-Independent DNA Damage Response R-HSA-69610
Programmed Cell Death R-HSA-5357801
Signaling by NOTCH4 R-HSA-9013694
Defective CFTR causes cystic fibrosis R-HSA-5678895
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
TCR signaling R-HSA-202403
Regulation of RAS by GAPs R-HSA-5658442
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of GLI1 by the proteasome R-HSA-5610780
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX2 expression and activity R-HSA-8939902
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Infectious disease R-HSA-5663205
Signaling by ROBO receptors R-HSA-376176
RAF/MAP kinase cascade R-HSA-5673001
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Vif-mediated degradation of APOBEC3G R-HSA-180585
Nervous system development R-HSA-9675108
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Beta-catenin independent WNT signaling R-HSA-3858494
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog ligand biogenesis R-HSA-5358346
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'on' state R-HSA-5632684
Cytokine Signaling in Immune system R-HSA-1280215
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
S Phase R-HSA-69242
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
MAPK family signaling cascades R-HSA-5683057
Signaling by WNT R-HSA-195721
Interleukin-1 family signaling R-HSA-446652
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
RNA Polymerase II Transcription R-HSA-73857
G2/M Transition R-HSA-69275
Cell Cycle Checkpoints R-HSA-69620
Mitotic G2-G2/M phases R-HSA-453274
Cellular response to hypoxia R-HSA-1234174
Ub-specific processing proteases R-HSA-5689880
Gene expression (Transcription) R-HSA-74160
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of GLI2 by the proteasome R-HSA-5610783
Apoptosis R-HSA-109581
Cell Cycle R-HSA-1640170
Post-translational protein modification R-HSA-597592
PIP3 activates AKT signaling R-HSA-1257604
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signal Transduction R-HSA-162582
Vif-mediated degradation of APOBEC3G R-HSA-180585
Neddylation R-HSA-8951664
Cell Cycle Checkpoints R-HSA-69620
Deubiquitination R-HSA-5688426
Hh mutants are degraded by ERAD R-HSA-5362768
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Anaphase R-HSA-68882
Asymmetric localization of PCP proteins R-HSA-4608870
Programmed Cell Death R-HSA-5357801
Negative regulation of NOTCH4 signaling R-HSA-9604323
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Metabolism of proteins R-HSA-392499
Hedgehog 'off' state R-HSA-5610787
Vpu mediated degradation of CD4 R-HSA-180534
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RUNX3 expression and activity R-HSA-8941858
Apoptosis R-HSA-109581
Orc1 removal from chromatin R-HSA-68949
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of NF-kappaB in B cells R-HSA-1169091
Adaptive Immune System R-HSA-1280218
Regulation of RUNX2 expression and activity R-HSA-8939902
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ER-Phagosome pathway R-HSA-1236974
Metabolism of polyamines R-HSA-351202
Antigen processing-Cross presentation R-HSA-1236975
PIP3 activates AKT signaling R-HSA-1257604
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle, Mitotic R-HSA-69278
Signaling by ROBO receptors R-HSA-376176
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ub-specific processing proteases R-HSA-5689880
S Phase R-HSA-69242
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Cyclin E associated events during G1/S transition R-HSA-69202
M Phase R-HSA-68886
Downstream TCR signaling R-HSA-202424
Nuclear events mediated by NFE2L2 R-HSA-9759194
HIV Infection R-HSA-162906
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Generic Transcription Pathway R-HSA-212436
Signaling by Interleukins R-HSA-449147
Gene expression (Transcription) R-HSA-74160
Cellular response to hypoxia R-HSA-1234174
Regulation of RAS by GAPs R-HSA-5658442
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G2/M Checkpoints R-HSA-69481
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX1 R-HSA-8878171
Innate Immune System R-HSA-168249
FCERI mediated NF-kB activation R-HSA-2871837
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX3 R-HSA-8878159
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Nervous system development R-HSA-9675108
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
DNA Replication Pre-Initiation R-HSA-69002
Signaling by WNT R-HSA-195721
Beta-catenin independent WNT signaling R-HSA-3858494
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Assembly of the pre-replicative complex R-HSA-68867
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic G2-G2/M phases R-HSA-453274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH4 R-HSA-9013694
Hedgehog 'on' state R-HSA-5632684
MAPK family signaling cascades R-HSA-5683057
Degradation of GLI1 by the proteasome R-HSA-5610780
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
Regulation of Apoptosis R-HSA-169911
Class I MHC mediated antigen processing & presentation R-HSA-983169
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
G2/M Transition R-HSA-69275
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism R-HSA-1430728
Switching of origins to a post-replicative state R-HSA-69052
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Post-translational protein modification R-HSA-597592
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCR signaling R-HSA-202403
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of amino acids and derivatives R-HSA-71291
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of AXIN R-HSA-4641257
Synthesis of DNA R-HSA-69239
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Interleukin-1 family signaling R-HSA-446652
DNA Replication R-HSA-69306
RAF/MAP kinase cascade R-HSA-5673001
Disorders of transmembrane transporters R-HSA-5619115
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of RNA R-HSA-8953854
Separation of Sister Chromatids R-HSA-2467813
Intracellular signaling by second messengers R-HSA-9006925
Signaling by NOTCH R-HSA-157118
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
G1/S DNA Damage Checkpoints R-HSA-69615
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MAPK6/MAPK4 signaling R-HSA-5687128
C-type lectin receptors (CLRs) R-HSA-5621481
ABC-family proteins mediated transport R-HSA-382556
Hedgehog ligand biogenesis R-HSA-5358346
PTEN Regulation R-HSA-6807070
Degradation of GLI2 by the proteasome R-HSA-5610783
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Host Interactions of HIV factors R-HSA-162909
Regulation of PTEN stability and activity R-HSA-8948751
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
ABC transporter disorders R-HSA-5619084
RNA Polymerase II Transcription R-HSA-73857
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Developmental Biology R-HSA-1266738
Cellular response to chemical stress R-HSA-9711123
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of DVL R-HSA-4641258
p53-Independent DNA Damage Response R-HSA-69610
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cytokine Signaling in Immune system R-HSA-1280215

Expression Atlas ENSG00000099341
NCBI gene (formerly Entrezgene) 5714
GeneCards 9566
HGNC Symbol HGNC:9566
MIM gene 617844
UniProtKB Gene Name V9HW09
WikiGene 5714
Gene: PSMB7
Ensembl ID : ENSG00000136930
Description: proteasome 20S subunit beta 7
Gene Synonyms: Z
6 APIs:
218 Possible Orthologues:

Degradation of GLI2 by the proteasome R-HSA-5610783
Disease R-HSA-1643685
Metabolism of RNA R-HSA-8953854
FCERI mediated NF-kB activation R-HSA-2871837
Neddylation R-HSA-8951664
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1 DNA Damage Response R-HSA-69563
Nervous system development R-HSA-9675108
Programmed Cell Death R-HSA-5357801
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of expression of SLITs and ROBOs R-HSA-9010553
FCERI mediated NF-kB activation R-HSA-2871837
C-type lectin receptors (CLRs) R-HSA-5621481
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of RNA R-HSA-8953854
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interleukin-1 signaling R-HSA-9020702
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to chemical stress R-HSA-9711123
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by WNT R-HSA-195721
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Negative regulation of NOTCH4 signaling R-HSA-9604323
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Ub-specific processing proteases R-HSA-5689880
HIV Infection R-HSA-162906
Orc1 removal from chromatin R-HSA-68949
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
PTEN Regulation R-HSA-6807070
Regulation of RAS by GAPs R-HSA-5658442
Gene expression (Transcription) R-HSA-74160
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Transport of small molecules R-HSA-382551
Switching of origins to a post-replicative state R-HSA-69052
Regulation of mitotic cell cycle R-HSA-453276
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RNA Polymerase II Transcription R-HSA-73857
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Synthesis of DNA R-HSA-69239
Apoptosis R-HSA-109581
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Asymmetric localization of PCP proteins R-HSA-4608870
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of RUNX2 expression and activity R-HSA-8939902
Intracellular signaling by second messengers R-HSA-9006925
Infectious disease R-HSA-5663205
Post-translational protein modification R-HSA-597592
ABC-family proteins mediated transport R-HSA-382556
Axon guidance R-HSA-422475
Regulation of Apoptosis R-HSA-169911
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of PTEN stability and activity R-HSA-8948751
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
Degradation of DVL R-HSA-4641258
Hedgehog 'on' state R-HSA-5632684
PCP/CE pathway R-HSA-4086400
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Independent DNA Damage Response R-HSA-69610
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
ER-Phagosome pathway R-HSA-1236974
Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
Hedgehog ligand biogenesis R-HSA-5358346
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH4 R-HSA-9013694
Adaptive Immune System R-HSA-1280218
Assembly of the pre-replicative complex R-HSA-68867
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by NOTCH R-HSA-157118
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX3 R-HSA-8878159
Disorders of transmembrane transporters R-HSA-5619115
Mitotic Metaphase and Anaphase R-HSA-2555396
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Disease R-HSA-1643685
Signaling by ROBO receptors R-HSA-376176
Mitotic Anaphase R-HSA-68882
ABC transporter disorders R-HSA-5619084
Degradation of AXIN R-HSA-4641257
Defective CFTR causes cystic fibrosis R-HSA-5678895
Separation of Sister Chromatids R-HSA-2467813
DNA Replication R-HSA-69306
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 family signaling R-HSA-446652
Stabilization of p53 R-HSA-69541
Hedgehog 'off' state R-HSA-5610787
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Deubiquitination R-HSA-5688426
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
UCH proteinases R-HSA-5689603
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by Interleukins R-HSA-449147
Signaling by NOTCH4 R-HSA-9013694
Orc1 removal from chromatin R-HSA-68949
Degradation of DVL R-HSA-4641258
Cellular response to hypoxia R-HSA-1234174
Axon guidance R-HSA-422475
Ub-specific processing proteases R-HSA-5689880
Switching of origins to a post-replicative state R-HSA-69052
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of polyamines R-HSA-351202
Downstream TCR signaling R-HSA-202424
Metabolism of RNA R-HSA-8953854
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neutrophil degranulation R-HSA-6798695
Synthesis of DNA R-HSA-69239
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of amino acids and derivatives R-HSA-71291
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Assembly of the pre-replicative complex R-HSA-68867
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic G2-G2/M phases R-HSA-453274
Generic Transcription Pathway R-HSA-212436
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Stabilization of p53 R-HSA-69541
Degradation of GLI2 by the proteasome R-HSA-5610783
RAF/MAP kinase cascade R-HSA-5673001
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652
PTEN Regulation R-HSA-6807070
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX1 R-HSA-8878171
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog 'off' state R-HSA-5610787
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX3 R-HSA-8878159
ABC transporter disorders R-HSA-5619084
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 signaling R-HSA-9020702
Transport of small molecules R-HSA-382551
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Metaphase and Anaphase R-HSA-2555396
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stimuli R-HSA-8953897
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
Separation of Sister Chromatids R-HSA-2467813
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of AXIN R-HSA-4641257
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S Transition R-HSA-69206
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Apoptosis R-HSA-109581
Neddylation R-HSA-8951664
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism R-HSA-1430728
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mitotic cell cycle R-HSA-453276
Mitotic Anaphase R-HSA-68882
Cell Cycle Checkpoints R-HSA-69620
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of beta-catenin by the destruction complex R-HSA-195253
DNA Replication Pre-Initiation R-HSA-69002
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular response to chemical stress R-HSA-9711123
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by ROBO receptors R-HSA-376176
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
HIV Infection R-HSA-162906
TCR signaling R-HSA-202403
Signaling by NOTCH R-HSA-157118
ER-Phagosome pathway R-HSA-1236974
S Phase R-HSA-69242
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
UCH proteinases R-HSA-5689603
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Interleukins R-HSA-449147
Regulation of RUNX3 expression and activity R-HSA-8941858
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Checkpoints R-HSA-69481
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Programmed Cell Death R-HSA-5357801
Cytokine Signaling in Immune system R-HSA-1280215
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Hedgehog R-HSA-5358351
MAPK family signaling cascades R-HSA-5683057
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants abrogate ligand secretion R-HSA-5387390
PIP3 activates AKT signaling R-HSA-1257604
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by WNT R-HSA-195721
Hedgehog 'on' state R-HSA-5632684
MAPK1/MAPK3 signaling R-HSA-5684996
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of PTEN stability and activity R-HSA-8948751
Immune System R-HSA-168256
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vif-mediated degradation of APOBEC3G R-HSA-180585
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Host Interactions of HIV factors R-HSA-162909
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK6/MAPK4 signaling R-HSA-5687128
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Innate Immune System R-HSA-168249
p53-Independent DNA Damage Response R-HSA-69610
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog 'off' state R-HSA-5610787
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of polyamines R-HSA-351202
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog ligand biogenesis R-HSA-5358346
Infectious disease R-HSA-5663205
DNA Replication R-HSA-69306
Disorders of transmembrane transporters R-HSA-5619115
G2/M Checkpoints R-HSA-69481
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Innate Immune System R-HSA-168249
M Phase R-HSA-68886
Stabilization of p53 R-HSA-69541
G2/M Transition R-HSA-69275
Antigen processing-Cross presentation R-HSA-1236975
Disease R-HSA-1643685
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH4 R-HSA-9013694
RNA Polymerase II Transcription R-HSA-73857
Downstream TCR signaling R-HSA-202424
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of Apoptosis R-HSA-169911
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCR signaling R-HSA-202403
Signal Transduction R-HSA-162582
G1/S Transition R-HSA-69206
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cyclin E associated events during G1/S transition R-HSA-69202
Assembly of the pre-replicative complex R-HSA-68867
Class I MHC mediated antigen processing & presentation R-HSA-983169
Adaptive Immune System R-HSA-1280218
Interleukin-1 family signaling R-HSA-446652
Metabolism of amino acids and derivatives R-HSA-71291
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cellular response to chemical stress R-HSA-9711123
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stress R-HSA-2262752
Signaling by Interleukins R-HSA-449147
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by ROBO receptors R-HSA-376176
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1 DNA Damage Response R-HSA-69563
Host Interactions of HIV factors R-HSA-162909
Cellular response to hypoxia R-HSA-1234174
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Post-translational protein modification R-HSA-597592
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Anaphase R-HSA-68882
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Synthesis of DNA R-HSA-69239
Transport of small molecules R-HSA-382551
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Metaphase and Anaphase R-HSA-2555396
C-type lectin receptors (CLRs) R-HSA-5621481
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PCP/CE pathway R-HSA-4086400
HIV Infection R-HSA-162906
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX3 expression and activity R-HSA-8941858
Nervous system development R-HSA-9675108
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
Axon guidance R-HSA-422475
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
Beta-catenin independent WNT signaling R-HSA-3858494
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC transporter disorders R-HSA-5619084
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of proteins R-HSA-392499
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RAF/MAP kinase cascade R-HSA-5673001
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Orc1 removal from chromatin R-HSA-68949
PTEN Regulation R-HSA-6807070
KEAP1-NFE2L2 pathway R-HSA-9755511
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Apoptosis R-HSA-109581
Signaling by NOTCH R-HSA-157118
Deubiquitination R-HSA-5688426
FCERI mediated NF-kB activation R-HSA-2871837
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of PTEN stability and activity R-HSA-8948751
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle Checkpoints R-HSA-69620
ER-Phagosome pathway R-HSA-1236974
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle R-HSA-1640170
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Immune System R-HSA-168256
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX1 R-HSA-8878171
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 signaling R-HSA-9020702
MAPK family signaling cascades R-HSA-5683057
Vif-mediated degradation of APOBEC3G R-HSA-180585
Neutrophil degranulation R-HSA-6798695
ABC-family proteins mediated transport R-HSA-382556
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S DNA Damage Checkpoints R-HSA-69615
PIP3 activates AKT signaling R-HSA-1257604
Separation of Sister Chromatids R-HSA-2467813
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
Switching of origins to a post-replicative state R-HSA-69052
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI2 by the proteasome R-HSA-5610783
Interleukin-1 family signaling R-HSA-446652
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Regulation of Apoptosis R-HSA-169911
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RUNX2 expression and activity R-HSA-8939902
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Apoptosis R-HSA-109581
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RAF/MAP kinase cascade R-HSA-5673001
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PTEN Regulation R-HSA-6807070
Signal Transduction R-HSA-162582
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC-family proteins mediated transport R-HSA-382556
RNA Polymerase II Transcription R-HSA-73857
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
G2/M Transition R-HSA-69275
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'off' state R-HSA-5610787
Deubiquitination R-HSA-5688426
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
TCF dependent signaling in response to WNT R-HSA-201681
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional regulation by RUNX1 R-HSA-8878171
G1/S DNA Damage Checkpoints R-HSA-69615
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G2-G2/M phases R-HSA-453274
MAPK family signaling cascades R-HSA-5683057
TCR signaling R-HSA-202403
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
Mitotic G1 phase and G1/S transition R-HSA-453279
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Vpu mediated degradation of CD4 R-HSA-180534
Separation of Sister Chromatids R-HSA-2467813
Metabolism R-HSA-1430728
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
CLEC7A (Dectin-1) signaling R-HSA-5607764
Axon guidance R-HSA-422475
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX3 expression and activity R-HSA-8941858
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
HIV Infection R-HSA-162906
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hh mutants are degraded by ERAD R-HSA-5362768
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
Regulation of RAS by GAPs R-HSA-5658442
G2/M Checkpoints R-HSA-69481
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
Signaling by NOTCH4 R-HSA-9013694
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cyclin E associated events during G1/S transition R-HSA-69202
UCH proteinases R-HSA-5689603
Neutrophil degranulation R-HSA-6798695
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
PCP/CE pathway R-HSA-4086400
Immune System R-HSA-168256
G1/S Transition R-HSA-69206
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle, Mitotic R-HSA-69278
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
Synthesis of DNA R-HSA-69239
Metabolism of RNA R-HSA-8953854
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transport of small molecules R-HSA-382551
Orc1 removal from chromatin R-HSA-68949
Signaling by Hedgehog R-HSA-5358351
Interleukin-1 signaling R-HSA-9020702
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of DVL R-HSA-4641258
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Cell Cycle Checkpoints R-HSA-69620
C-type lectin receptors (CLRs) R-HSA-5621481
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle R-HSA-1640170
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream TCR signaling R-HSA-202424
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Gene expression (Transcription) R-HSA-74160
Ub-specific processing proteases R-HSA-5689880
Disorders of transmembrane transporters R-HSA-5619115
Host Interactions of HIV factors R-HSA-162909
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Programmed Cell Death R-HSA-5357801
Metabolism of polyamines R-HSA-351202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
Neddylation R-HSA-8951664
DNA Replication R-HSA-69306
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ER-Phagosome pathway R-HSA-1236974
Antigen processing-Cross presentation R-HSA-1236975
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by ROBO receptors R-HSA-376176
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of DVL R-HSA-4641258
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
Cyclin E associated events during G1/S transition R-HSA-69202
ABC transporter disorders R-HSA-5619084
Signaling by Interleukins R-HSA-449147
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH4 R-HSA-9013694
Hh mutants abrogate ligand secretion R-HSA-5387390
PTEN Regulation R-HSA-6807070
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G2-G2/M phases R-HSA-453274
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Synthesis of DNA R-HSA-69239
Deubiquitination R-HSA-5688426
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TCR signaling R-HSA-202403
Regulation of RUNX2 expression and activity R-HSA-8939902
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Generic Transcription Pathway R-HSA-212436
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Beta-catenin independent WNT signaling R-HSA-3858494
Ub-specific processing proteases R-HSA-5689880
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Switching of origins to a post-replicative state R-HSA-69052
Orc1 removal from chromatin R-HSA-68949
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Programmed Cell Death R-HSA-5357801
M Phase R-HSA-68886
NIK-->noncanonical NF-kB signaling R-HSA-5676590
C-type lectin receptors (CLRs) R-HSA-5621481
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Separation of Sister Chromatids R-HSA-2467813
Assembly of the pre-replicative complex R-HSA-68867
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S DNA Damage Checkpoints R-HSA-69615
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Independent DNA Damage Response R-HSA-69610
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH R-HSA-157118
Hh mutants are degraded by ERAD R-HSA-5362768
Nervous system development R-HSA-9675108
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'off' state R-HSA-5610787
Host Interactions of HIV factors R-HSA-162909
Neutrophil degranulation R-HSA-6798695
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
RAF/MAP kinase cascade R-HSA-5673001
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
Signal Transduction R-HSA-162582
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of PTEN stability and activity R-HSA-8948751
Intracellular signaling by second messengers R-HSA-9006925
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Adaptive Immune System R-HSA-1280218
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic Metaphase and Anaphase R-HSA-2555396
HIV Infection R-HSA-162906
Downstream TCR signaling R-HSA-202424
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle, Mitotic R-HSA-69278
ABC-family proteins mediated transport R-HSA-382556
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of Apoptosis R-HSA-169911
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Axon guidance R-HSA-422475
PCP/CE pathway R-HSA-4086400
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
Developmental Biology R-HSA-1266738
Transport of small molecules R-HSA-382551
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle R-HSA-1640170
Immune System R-HSA-168256
Transcriptional regulation by RUNX2 R-HSA-8878166
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog ligand biogenesis R-HSA-5358346
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK family signaling cascades R-HSA-5683057
Cell Cycle Checkpoints R-HSA-69620
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Replication Pre-Initiation R-HSA-69002
Degradation of beta-catenin by the destruction complex R-HSA-195253
Innate Immune System R-HSA-168249
Apoptosis R-HSA-109581
Interleukin-1 family signaling R-HSA-446652
DNA Replication R-HSA-69306
Cellular response to hypoxia R-HSA-1234174
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of AXIN R-HSA-4641257
Regulation of RUNX3 expression and activity R-HSA-8941858
Post-translational protein modification R-HSA-597592
Cytokine Signaling in Immune system R-HSA-1280215
UCH proteinases R-HSA-5689603
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signaling by WNT R-HSA-195721
Neddylation R-HSA-8951664
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
Metabolism of amino acids and derivatives R-HSA-71291
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism R-HSA-1430728
Interleukin-1 signaling R-HSA-9020702
G2/M Transition R-HSA-69275
G1/S Transition R-HSA-69206
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of polyamines R-HSA-351202
Mitotic Anaphase R-HSA-68882
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Innate Immune System R-HSA-168249
Negative regulation of NOTCH4 signaling R-HSA-9604323
Gene expression (Transcription) R-HSA-74160
Degradation of GLI2 by the proteasome R-HSA-5610783
PTEN Regulation R-HSA-6807070
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by Hedgehog R-HSA-5358351
Interleukin-1 signaling R-HSA-9020702
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signal Transduction R-HSA-162582
MAPK6/MAPK4 signaling R-HSA-5687128
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
S Phase R-HSA-69242
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX1 R-HSA-8878171
G2/M Transition R-HSA-69275
Hedgehog 'on' state R-HSA-5632684
Mitotic Anaphase R-HSA-68882
Generic Transcription Pathway R-HSA-212436
Regulation of PTEN stability and activity R-HSA-8948751
KEAP1-NFE2L2 pathway R-HSA-9755511
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
Asymmetric localization of PCP proteins R-HSA-4608870
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by NOTCH R-HSA-157118
Metabolism R-HSA-1430728
Cellular response to chemical stress R-HSA-9711123
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by WNT R-HSA-195721
Regulation of mitotic cell cycle R-HSA-453276
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Switching of origins to a post-replicative state R-HSA-69052
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
Developmental Biology R-HSA-1266738
Synthesis of DNA R-HSA-69239
PCP/CE pathway R-HSA-4086400
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S Transition R-HSA-69206
Antigen processing-Cross presentation R-HSA-1236975
Class I MHC mediated antigen processing & presentation R-HSA-983169
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
M Phase R-HSA-68886
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Downstream TCR signaling R-HSA-202424
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent DNA Damage Response R-HSA-69610
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
Cyclin E associated events during G1/S transition R-HSA-69202
Deubiquitination R-HSA-5688426
G1/S DNA Damage Checkpoints R-HSA-69615
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of RAS by GAPs R-HSA-5658442
UCH proteinases R-HSA-5689603
Infectious disease R-HSA-5663205
Neutrophil degranulation R-HSA-6798695
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ub-specific processing proteases R-HSA-5689880
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK family signaling cascades R-HSA-5683057
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transport of small molecules R-HSA-382551
Hedgehog 'off' state R-HSA-5610787
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
C-type lectin receptors (CLRs) R-HSA-5621481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stress R-HSA-2262752
Degradation of beta-catenin by the destruction complex R-HSA-195253
Axon guidance R-HSA-422475
Interleukin-1 family signaling R-HSA-446652
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Adaptive Immune System R-HSA-1280218
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of DVL R-HSA-4641258
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by NOTCH4 R-HSA-9013694
MAPK1/MAPK3 signaling R-HSA-5684996
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ER-Phagosome pathway R-HSA-1236974
ABC-family proteins mediated transport R-HSA-382556
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of AXIN R-HSA-4641257
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of polyamines R-HSA-351202
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Metaphase and Anaphase R-HSA-2555396
HIV Infection R-HSA-162906
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Activation of NF-kappaB in B cells R-HSA-1169091
G2/M Checkpoints R-HSA-69481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PIP3 activates AKT signaling R-HSA-1257604
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Beta-catenin independent WNT signaling R-HSA-3858494
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by ROBO receptors R-HSA-376176
Mitotic G1 phase and G1/S transition R-HSA-453279
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by WNT R-HSA-195721
MAPK family signaling cascades R-HSA-5683057
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX3 R-HSA-8878159
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Degradation of DVL R-HSA-4641258
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle, Mitotic R-HSA-69278
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Disease R-HSA-1643685
Axon guidance R-HSA-422475
RAF/MAP kinase cascade R-HSA-5673001
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog ligand biogenesis R-HSA-5358346
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
Hedgehog 'on' state R-HSA-5632684
Nuclear events mediated by NFE2L2 R-HSA-9759194
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Cyclin E associated events during G1/S transition R-HSA-69202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RUNX2 expression and activity R-HSA-8939902
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX1 R-HSA-8878171
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants are degraded by ERAD R-HSA-5362768
Signal Transduction R-HSA-162582
G1/S Transition R-HSA-69206
Deubiquitination R-HSA-5688426
Developmental Biology R-HSA-1266738
Interleukin-1 family signaling R-HSA-446652
ABC transporter disorders R-HSA-5619084
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
C-type lectin receptors (CLRs) R-HSA-5621481
G2/M Transition R-HSA-69275
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of RAS by GAPs R-HSA-5658442
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Immune System R-HSA-168256
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of AXIN R-HSA-4641257
Synthesis of DNA R-HSA-69239
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
FCERI mediated NF-kB activation R-HSA-2871837
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Signaling by Interleukins R-HSA-449147
Neddylation R-HSA-8951664
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic G1 phase and G1/S transition R-HSA-453279
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Neutrophil degranulation R-HSA-6798695
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Apoptosis R-HSA-109581
Signaling by NOTCH4 R-HSA-9013694
Nervous system development R-HSA-9675108
Mitotic Anaphase R-HSA-68882
HIV Infection R-HSA-162906
Orc1 removal from chromatin R-HSA-68949
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of RNA R-HSA-8953854
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by ROBO receptors R-HSA-376176
Infectious disease R-HSA-5663205
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of polyamines R-HSA-351202
Cell Cycle R-HSA-1640170
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
S Phase R-HSA-69242
Ub-specific processing proteases R-HSA-5689880
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Separation of Sister Chromatids R-HSA-2467813
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Programmed Cell Death R-HSA-5357801
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RUNX3 expression and activity R-HSA-8941858
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
PCP/CE pathway R-HSA-4086400
G1/S DNA Damage Checkpoints R-HSA-69615
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK6/MAPK4 signaling R-HSA-5687128
M Phase R-HSA-68886
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Vif-mediated degradation of APOBEC3G R-HSA-180585
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI1 by the proteasome R-HSA-5610780
Disorders of transmembrane transporters R-HSA-5619115
Degradation of beta-catenin by the destruction complex R-HSA-195253
ER-Phagosome pathway R-HSA-1236974
Transport of small molecules R-HSA-382551
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TCF dependent signaling in response to WNT R-HSA-201681
Antigen processing-Cross presentation R-HSA-1236975
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G2/M Checkpoints R-HSA-69481
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
Interleukin-1 family signaling R-HSA-446652
Antigen processing-Cross presentation R-HSA-1236975
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PIP3 activates AKT signaling R-HSA-1257604
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
HIV Infection R-HSA-162906
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'on' state R-HSA-5632684
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
Regulation of Apoptosis R-HSA-169911
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
PCP/CE pathway R-HSA-4086400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S Transition R-HSA-69206
Immune System R-HSA-168256
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
Infectious disease R-HSA-5663205
Transport of small molecules R-HSA-382551
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular response to hypoxia R-HSA-1234174
Switching of origins to a post-replicative state R-HSA-69052
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent DNA Damage Response R-HSA-69610
Transcriptional regulation by RUNX3 R-HSA-8878159
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of RAS by GAPs R-HSA-5658442
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Synthesis of DNA R-HSA-69239
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
Hh mutants abrogate ligand secretion R-HSA-5387390
TCR signaling R-HSA-202403
Metabolism R-HSA-1430728
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Anaphase R-HSA-68882
Metabolism of polyamines R-HSA-351202
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular responses to stimuli R-HSA-8953897
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Deubiquitination R-HSA-5688426
Activation of NF-kappaB in B cells R-HSA-1169091
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Defective CFTR causes cystic fibrosis R-HSA-5678895
Adaptive Immune System R-HSA-1280218
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Assembly of the pre-replicative complex R-HSA-68867
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
Mitotic G1 phase and G1/S transition R-HSA-453279
Disorders of transmembrane transporters R-HSA-5619115
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by ROBO receptors R-HSA-376176
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of AXIN R-HSA-4641257
Hedgehog ligand biogenesis R-HSA-5358346
M Phase R-HSA-68886
Cellular response to chemical stress R-HSA-9711123
TCF dependent signaling in response to WNT R-HSA-201681
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle Checkpoints R-HSA-69620
Neddylation R-HSA-8951664
Hedgehog 'off' state R-HSA-5610787
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of PTEN stability and activity R-HSA-8948751
Transcriptional regulation by RUNX2 R-HSA-8878166
Vif-mediated degradation of APOBEC3G R-HSA-180585
MAPK6/MAPK4 signaling R-HSA-5687128
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 signaling R-HSA-9020702
Nervous system development R-HSA-9675108
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
C-type lectin receptors (CLRs) R-HSA-5621481
Developmental Biology R-HSA-1266738
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by NOTCH R-HSA-157118
Cell Cycle R-HSA-1640170
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
Apoptosis R-HSA-109581
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by Interleukins R-HSA-449147
DNA Replication Pre-Initiation R-HSA-69002
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
ER-Phagosome pathway R-HSA-1236974
Cell Cycle, Mitotic R-HSA-69278
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
KEAP1-NFE2L2 pathway R-HSA-9755511
Generic Transcription Pathway R-HSA-212436
Degradation of GLI2 by the proteasome R-HSA-5610783
Post-translational protein modification R-HSA-597592
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by WNT R-HSA-195721
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of RNA R-HSA-8953854
Signaling by NOTCH4 R-HSA-9013694
ABC-family proteins mediated transport R-HSA-382556
Host Interactions of HIV factors R-HSA-162909
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of proteins R-HSA-392499
Axon guidance R-HSA-422475
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of RUNX3 expression and activity R-HSA-8941858
Immune System R-HSA-168256
Signaling by NOTCH R-HSA-157118
Degradation of GLI2 by the proteasome R-HSA-5610783
TCR signaling R-HSA-202403
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication R-HSA-69306
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Transition R-HSA-69275
Axon guidance R-HSA-422475
Cell Cycle R-HSA-1640170
Signaling by Hedgehog R-HSA-5358351
Mitotic Anaphase R-HSA-68882
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Downstream TCR signaling R-HSA-202424
ABC-family proteins mediated transport R-HSA-382556
HIV Infection R-HSA-162906
Cell Cycle, Mitotic R-HSA-69278
Separation of Sister Chromatids R-HSA-2467813
S Phase R-HSA-69242
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
Adaptive Immune System R-HSA-1280218
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular response to hypoxia R-HSA-1234174
Hh mutants abrogate ligand secretion R-HSA-5387390
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent DNA Damage Response R-HSA-69610
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Gene expression (Transcription) R-HSA-74160
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
DNA Replication Pre-Initiation R-HSA-69002
Interleukin-1 family signaling R-HSA-446652
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ub-specific processing proteases R-HSA-5689880
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic G2-G2/M phases R-HSA-453274
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cyclin E associated events during G1/S transition R-HSA-69202
Switching of origins to a post-replicative state R-HSA-69052
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
KEAP1-NFE2L2 pathway R-HSA-9755511
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH4 R-HSA-9013694
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Post-translational protein modification R-HSA-597592
Nervous system development R-HSA-9675108
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle Checkpoints R-HSA-69620
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signal Transduction R-HSA-162582
Regulation of RAS by GAPs R-HSA-5658442
TCF dependent signaling in response to WNT R-HSA-201681
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 signaling R-HSA-9020702
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Metaphase and Anaphase R-HSA-2555396
G2/M Checkpoints R-HSA-69481
Deubiquitination R-HSA-5688426
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX3 R-HSA-8878159
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by ROBO receptors R-HSA-376176
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Programmed Cell Death R-HSA-5357801
Hh mutants are degraded by ERAD R-HSA-5362768
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
FCERI mediated NF-kB activation R-HSA-2871837
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PIP3 activates AKT signaling R-HSA-1257604
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Regulation of Apoptosis R-HSA-169911
Orc1 removal from chromatin R-HSA-68949
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
Activation of NF-kappaB in B cells R-HSA-1169091
Apoptosis R-HSA-109581
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of GLI1 by the proteasome R-HSA-5610780
M Phase R-HSA-68886
Defective CFTR causes cystic fibrosis R-HSA-5678895
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RUNX2 expression and activity R-HSA-8939902
Vif-mediated degradation of APOBEC3G R-HSA-180585
Stabilization of p53 R-HSA-69541
Hedgehog 'on' state R-HSA-5632684
Assembly of the pre-replicative complex R-HSA-68867
Neddylation R-HSA-8951664
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by WNT R-HSA-195721
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
Metabolism of polyamines R-HSA-351202
Neutrophil degranulation R-HSA-6798695
ABC transporter disorders R-HSA-5619084
MAPK family signaling cascades R-HSA-5683057
Hedgehog 'off' state R-HSA-5610787
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vpu mediated degradation of CD4 R-HSA-180534
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by Interleukins R-HSA-449147
Degradation of AXIN R-HSA-4641257
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by the B Cell Receptor (BCR) R-HSA-983705
S Phase R-HSA-69242
DNA Replication Pre-Initiation R-HSA-69002
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'on' state R-HSA-5632684
Regulation of PTEN stability and activity R-HSA-8948751
Vpu mediated degradation of CD4 R-HSA-180534
Generic Transcription Pathway R-HSA-212436
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by Hedgehog R-HSA-5358351
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transcriptional regulation by RUNX3 R-HSA-8878159
MAPK1/MAPK3 signaling R-HSA-5684996
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
HIV Infection R-HSA-162906
Gene expression (Transcription) R-HSA-74160
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
Regulation of mitotic cell cycle R-HSA-453276
Signaling by WNT R-HSA-195721
Cellular response to chemical stress R-HSA-9711123
Apoptosis R-HSA-109581
Metabolism of RNA R-HSA-8953854
PIP3 activates AKT signaling R-HSA-1257604
TCF dependent signaling in response to WNT R-HSA-201681
Orc1 removal from chromatin R-HSA-68949
Transport of small molecules R-HSA-382551
Programmed Cell Death R-HSA-5357801
Interleukin-1 signaling R-HSA-9020702
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Assembly of the pre-replicative complex R-HSA-68867
Signaling by NOTCH4 R-HSA-9013694
Mitotic Metaphase and Anaphase R-HSA-2555396
Interleukin-1 family signaling R-HSA-446652
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
ABC transporter disorders R-HSA-5619084
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated NF-kB activation R-HSA-2871837
Separation of Sister Chromatids R-HSA-2467813
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G1/S Transition R-HSA-69206
Cell Cycle Checkpoints R-HSA-69620
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of amino acids and derivatives R-HSA-71291
Disorders of transmembrane transporters R-HSA-5619115
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
Neutrophil degranulation R-HSA-6798695
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of DVL R-HSA-4641258
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Downstream TCR signaling R-HSA-202424
RAF/MAP kinase cascade R-HSA-5673001
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular responses to stress R-HSA-2262752
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism of polyamines R-HSA-351202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Axon guidance R-HSA-422475
PCP/CE pathway R-HSA-4086400
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to hypoxia R-HSA-1234174
Immune System R-HSA-168256
G2/M Checkpoints R-HSA-69481
Regulation of RAS by GAPs R-HSA-5658442
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Disease R-HSA-1643685
Hedgehog ligand biogenesis R-HSA-5358346
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Post-translational protein modification R-HSA-597592
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Deubiquitination R-HSA-5688426
Degradation of GLI2 by the proteasome R-HSA-5610783
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Vif-mediated degradation of APOBEC3G R-HSA-180585
Host Interactions of HIV factors R-HSA-162909
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism R-HSA-1430728
Adaptive Immune System R-HSA-1280218
Intracellular signaling by second messengers R-HSA-9006925
Regulation of Apoptosis R-HSA-169911
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Developmental Biology R-HSA-1266738
G1/S DNA Damage Checkpoints R-HSA-69615
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication R-HSA-69306
Nervous system development R-HSA-9675108
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signal Transduction R-HSA-162582
ER-Phagosome pathway R-HSA-1236974
p53-Independent DNA Damage Response R-HSA-69610
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RUNX2 expression and activity R-HSA-8939902
UCH proteinases R-HSA-5689603
Metabolism of proteins R-HSA-392499
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCR signaling R-HSA-202403
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by ROBO receptors R-HSA-376176
Signaling by Interleukins R-HSA-449147
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK family signaling cascades R-HSA-5683057
Cell Cycle, Mitotic R-HSA-69278
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ABC-family proteins mediated transport R-HSA-382556
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of NF-kappaB in B cells R-HSA-1169091
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Beta-catenin independent WNT signaling R-HSA-3858494
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX1 R-HSA-8878171
RNA Polymerase II Transcription R-HSA-73857
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX2 R-HSA-8878166

Expression Atlas ENSG00000136930
NCBI gene (formerly Entrezgene) 5695
GeneCards 9544
HGNC Symbol HGNC:9544
MIM gene 604030
UniProtKB Gene Name Q99436
WikiGene 5695
Gene: PSMB4
Ensembl ID : ENSG00000159377
Description: proteasome 20S subunit beta 4
Gene Synonyms: HN3,PROS26
6 APIs:
214 Possible Orthologues:

UCH proteinases R-HSA-5689603
Assembly of the pre-replicative complex R-HSA-68867
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
Activation of NF-kappaB in B cells R-HSA-1169091
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to chemical stress R-HSA-9711123
Negative regulation of NOTCH4 signaling R-HSA-9604323
TCR signaling R-HSA-202403
Separation of Sister Chromatids R-HSA-2467813
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of AXIN R-HSA-4641257
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ER-Phagosome pathway R-HSA-1236974
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of polyamines R-HSA-351202
Hedgehog ligand biogenesis R-HSA-5358346
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle R-HSA-1640170
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'on' state R-HSA-5632684
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX2 R-HSA-8878166
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
Disease R-HSA-1643685
Mitotic G1 phase and G1/S transition R-HSA-453279
Intracellular signaling by second messengers R-HSA-9006925
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stimuli R-HSA-8953897
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog 'off' state R-HSA-5610787
Cell Cycle, Mitotic R-HSA-69278
Synthesis of DNA R-HSA-69239
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Switching of origins to a post-replicative state R-HSA-69052
ABC transporter disorders R-HSA-5619084
G2/M Transition R-HSA-69275
Vif-mediated degradation of APOBEC3G R-HSA-180585
Vpu mediated degradation of CD4 R-HSA-180534
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of RAS by GAPs R-HSA-5658442
Developmental Biology R-HSA-1266738
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Antigen processing-Cross presentation R-HSA-1236975
Mitotic G2-G2/M phases R-HSA-453274
S Phase R-HSA-69242
Transport of small molecules R-HSA-382551
ABC-family proteins mediated transport R-HSA-382556
Infectious disease R-HSA-5663205
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH4 R-HSA-9013694
Mitotic Anaphase R-HSA-68882
Disorders of transmembrane transporters R-HSA-5619115
G2/M Checkpoints R-HSA-69481
Adaptive Immune System R-HSA-1280218
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants are degraded by ERAD R-HSA-5362768
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Asymmetric localization of PCP proteins R-HSA-4608870
Gene expression (Transcription) R-HSA-74160
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Independent DNA Damage Response R-HSA-69610
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
PTEN Regulation R-HSA-6807070
Regulation of mitotic cell cycle R-HSA-453276
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
Downstream TCR signaling R-HSA-202424
FCERI mediated NF-kB activation R-HSA-2871837
Ub-specific processing proteases R-HSA-5689880
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Post-translational protein modification R-HSA-597592
Signal Transduction R-HSA-162582
DNA Replication R-HSA-69306
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Apoptosis R-HSA-109581
Axon guidance R-HSA-422475
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of DVL R-HSA-4641258
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism R-HSA-1430728
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by NOTCH R-HSA-157118
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by ROBO receptors R-HSA-376176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
HIV Infection R-HSA-162906
Neddylation R-HSA-8951664
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Interleukins R-HSA-449147
Signaling by Hedgehog R-HSA-5358351
Cytokine Signaling in Immune system R-HSA-1280215
Negative regulation of NOTCH4 signaling R-HSA-9604323
DNA Replication Pre-Initiation R-HSA-69002
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog 'off' state R-HSA-5610787
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog ligand biogenesis R-HSA-5358346
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PCP/CE pathway R-HSA-4086400
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of PTEN stability and activity R-HSA-8948751
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Adaptive Immune System R-HSA-1280218
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle, Mitotic R-HSA-69278
Degradation of AXIN R-HSA-4641257
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
Signaling by ROBO receptors R-HSA-376176
Hh mutants abrogate ligand secretion R-HSA-5387390
Orc1 removal from chromatin R-HSA-68949
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC transporter disorders R-HSA-5619084
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
M Phase R-HSA-68886
S Phase R-HSA-69242
Synthesis of DNA R-HSA-69239
RAF/MAP kinase cascade R-HSA-5673001
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX1 R-HSA-8878171
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream TCR signaling R-HSA-202424
G2/M Checkpoints R-HSA-69481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Assembly of the pre-replicative complex R-HSA-68867
Host Interactions of HIV factors R-HSA-162909
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HIV Infection R-HSA-162906
FCERI mediated NF-kB activation R-HSA-2871837
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to hypoxia R-HSA-1234174
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Neddylation R-HSA-8951664
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of RNA R-HSA-8953854
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Hedgehog R-HSA-5358351
TCR signaling R-HSA-202403
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
C-type lectin receptors (CLRs) R-HSA-5621481
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
Axon guidance R-HSA-422475
Immune System R-HSA-168256
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of proteins R-HSA-392499
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transport of small molecules R-HSA-382551
Metabolism of polyamines R-HSA-351202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Switching of origins to a post-replicative state R-HSA-69052
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by WNT R-HSA-195721
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing-Cross presentation R-HSA-1236975
Deubiquitination R-HSA-5688426
Regulation of RUNX2 expression and activity R-HSA-8939902
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by NOTCH4 R-HSA-9013694
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle R-HSA-1640170
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
Separation of Sister Chromatids R-HSA-2467813
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of Apoptosis R-HSA-169911
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular responses to stress R-HSA-2262752
Stabilization of p53 R-HSA-69541
Degradation of DVL R-HSA-4641258
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX3 R-HSA-8878159
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
ER-Phagosome pathway R-HSA-1236974
PTEN Regulation R-HSA-6807070
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK1/MAPK3 signaling R-HSA-5684996
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Vif-mediated degradation of APOBEC3G R-HSA-180585
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cyclin E associated events during G1/S transition R-HSA-69202
Class I MHC mediated antigen processing & presentation R-HSA-983169
RAF/MAP kinase cascade R-HSA-5673001
Host Interactions of HIV factors R-HSA-162909
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Transition R-HSA-69275
Hedgehog 'on' state R-HSA-5632684
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S DNA Damage Checkpoints R-HSA-69615
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stimuli R-HSA-8953897
Neddylation R-HSA-8951664
Vif-mediated degradation of APOBEC3G R-HSA-180585
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of amino acids and derivatives R-HSA-71291
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX2 R-HSA-8878166
Ub-specific processing proteases R-HSA-5689880
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of expression of SLITs and ROBOs R-HSA-9010553
KEAP1-NFE2L2 pathway R-HSA-9755511
Disease R-HSA-1643685
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of DVL R-HSA-4641258
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PIP3 activates AKT signaling R-HSA-1257604
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Anaphase R-HSA-68882
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of DNA R-HSA-69239
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX3 R-HSA-8878159
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 signaling R-HSA-9020702
M Phase R-HSA-68886
Metabolism of polyamines R-HSA-351202
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to hypoxia R-HSA-1234174
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of proteins R-HSA-392499
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interleukin-1 family signaling R-HSA-446652
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transport of small molecules R-HSA-382551
RNA Polymerase II Transcription R-HSA-73857
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by WNT R-HSA-195721
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Regulation of RAS by GAPs R-HSA-5658442
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
HIV Infection R-HSA-162906
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by NOTCH R-HSA-157118
Stabilization of p53 R-HSA-69541
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
ABC transporter disorders R-HSA-5619084
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of AXIN R-HSA-4641257
Hh mutants are degraded by ERAD R-HSA-5362768
Immune System R-HSA-168256
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing-Cross presentation R-HSA-1236975
MAPK6/MAPK4 signaling R-HSA-5687128
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of RNA R-HSA-8953854
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'off' state R-HSA-5610787
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
ER-Phagosome pathway R-HSA-1236974
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of Apoptosis R-HSA-169911
Mitotic G2-G2/M phases R-HSA-453274
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular response to hypoxia R-HSA-1234174
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
Intracellular signaling by second messengers R-HSA-9006925
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Ub-specific processing proteases R-HSA-5689880
Hh mutants are degraded by ERAD R-HSA-5362768
Post-translational protein modification R-HSA-597592
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by WNT R-HSA-195721
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by NOTCH4 R-HSA-9013694
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of DVL R-HSA-4641258
G2/M Transition R-HSA-69275
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle Checkpoints R-HSA-69620
Signaling by ROBO receptors R-HSA-376176
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Interleukin-1 signaling R-HSA-9020702
Generic Transcription Pathway R-HSA-212436
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog ligand biogenesis R-HSA-5358346
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of PTEN stability and activity R-HSA-8948751
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Anaphase R-HSA-68882
Neddylation R-HSA-8951664
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
Axon guidance R-HSA-422475
PTEN Regulation R-HSA-6807070
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
Asymmetric localization of PCP proteins R-HSA-4608870
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
Nervous system development R-HSA-9675108
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX3 R-HSA-8878159
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
Negative regulation of NOTCH4 signaling R-HSA-9604323
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Nuclear events mediated by NFE2L2 R-HSA-9759194
ABC transporter disorders R-HSA-5619084
MAPK1/MAPK3 signaling R-HSA-5684996
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by Interleukins R-HSA-449147
Deubiquitination R-HSA-5688426
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cyclin E associated events during G1/S transition R-HSA-69202
Orc1 removal from chromatin R-HSA-68949
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
PCP/CE pathway R-HSA-4086400
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of RNA R-HSA-8953854
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of proteins R-HSA-392499
Degradation of AXIN R-HSA-4641257
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Gene expression (Transcription) R-HSA-74160
Host Interactions of HIV factors R-HSA-162909
Infectious disease R-HSA-5663205
Developmental Biology R-HSA-1266738
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Stabilization of p53 R-HSA-69541
Hedgehog 'on' state R-HSA-5632684
Innate Immune System R-HSA-168249
HIV Infection R-HSA-162906
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RAF/MAP kinase cascade R-HSA-5673001
Synthesis of DNA R-HSA-69239
Switching of origins to a post-replicative state R-HSA-69052
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent DNA Damage Response R-HSA-69610
UCH proteinases R-HSA-5689603
Metabolism R-HSA-1430728
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX2 expression and activity R-HSA-8939902
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of AXIN R-HSA-4641257
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Mitotic Anaphase R-HSA-68882
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
UCH proteinases R-HSA-5689603
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle, Mitotic R-HSA-69278
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hh mutants abrogate ligand secretion R-HSA-5387390
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX1 R-HSA-8878171
Transport of small molecules R-HSA-382551
Innate Immune System R-HSA-168249
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RUNX3 expression and activity R-HSA-8941858
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Orc1 removal from chromatin R-HSA-68949
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Cellular responses to stress R-HSA-2262752
Metabolism of RNA R-HSA-8953854
Asymmetric localization of PCP proteins R-HSA-4608870
Adaptive Immune System R-HSA-1280218
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Signaling by NOTCH4 R-HSA-9013694
CLEC7A (Dectin-1) signaling R-HSA-5607764
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog ligand biogenesis R-HSA-5358346
HIV Infection R-HSA-162906
Cellular response to chemical stress R-HSA-9711123
Synthesis of DNA R-HSA-69239
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
S Phase R-HSA-69242
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by WNT R-HSA-195721
Metabolism of proteins R-HSA-392499
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stimuli R-HSA-8953897
Axon guidance R-HSA-422475
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mitotic cell cycle R-HSA-453276
Class I MHC mediated antigen processing & presentation R-HSA-983169
Nervous system development R-HSA-9675108
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
Signaling by ROBO receptors R-HSA-376176
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of DVL R-HSA-4641258
Neddylation R-HSA-8951664
Host Interactions of HIV factors R-HSA-162909
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Vpu mediated degradation of CD4 R-HSA-180534
Stabilization of p53 R-HSA-69541
Assembly of the pre-replicative complex R-HSA-68867
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI1 by the proteasome R-HSA-5610780
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Downstream TCR signaling R-HSA-202424
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Replication R-HSA-69306
Signaling by Interleukins R-HSA-449147
G2/M Checkpoints R-HSA-69481
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Antigen processing-Cross presentation R-HSA-1236975
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX3 R-HSA-8878159
RAF/MAP kinase cascade R-HSA-5673001
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disease R-HSA-1643685
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
ER-Phagosome pathway R-HSA-1236974
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism R-HSA-1430728
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
TCR signaling R-HSA-202403
Signaling by Hedgehog R-HSA-5358351
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Interleukin-1 family signaling R-HSA-446652
Disorders of transmembrane transporters R-HSA-5619115
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
Innate Immune System R-HSA-168249
Stabilization of p53 R-HSA-69541
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Apoptosis R-HSA-109581
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
DNA Replication R-HSA-69306
Ub-specific processing proteases R-HSA-5689880
Infectious disease R-HSA-5663205
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PIP3 activates AKT signaling R-HSA-1257604
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of AXIN R-HSA-4641257
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by NOTCH4 R-HSA-9013694
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hh mutants are degraded by ERAD R-HSA-5362768
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism R-HSA-1430728
Nuclear events mediated by NFE2L2 R-HSA-9759194
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication Pre-Initiation R-HSA-69002
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PCP/CE pathway R-HSA-4086400
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stimuli R-HSA-8953897
Mitotic Anaphase R-HSA-68882
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
C-type lectin receptors (CLRs) R-HSA-5621481
Axon guidance R-HSA-422475
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
TCR signaling R-HSA-202403
Regulation of mitotic cell cycle R-HSA-453276
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'off' state R-HSA-5610787
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH R-HSA-157118
Transport of small molecules R-HSA-382551
Nervous system development R-HSA-9675108
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
KEAP1-NFE2L2 pathway R-HSA-9755511
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Programmed Cell Death R-HSA-5357801
Degradation of DVL R-HSA-4641258
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of amino acids and derivatives R-HSA-71291
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream TCR signaling R-HSA-202424
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
G1/S DNA Damage Checkpoints R-HSA-69615
Generic Transcription Pathway R-HSA-212436
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular response to hypoxia R-HSA-1234174
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle R-HSA-1640170
Metabolism of proteins R-HSA-392499
Hedgehog 'on' state R-HSA-5632684
Post-translational protein modification R-HSA-597592
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
TCF dependent signaling in response to WNT R-HSA-201681
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Antigen processing-Cross presentation R-HSA-1236975
Assembly of the pre-replicative complex R-HSA-68867
ABC transporter disorders R-HSA-5619084
ABC-family proteins mediated transport R-HSA-382556
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular response to chemical stress R-HSA-9711123
Regulation of RAS by GAPs R-HSA-5658442
UCH proteinases R-HSA-5689603
G1/S Transition R-HSA-69206
Signal Transduction R-HSA-162582
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX3 R-HSA-8878159
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of GLI2 by the proteasome R-HSA-5610783
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G1 phase and G1/S transition R-HSA-453279
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
Downstream TCR signaling R-HSA-202424
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Assembly of the pre-replicative complex R-HSA-68867
ABC transporter disorders R-HSA-5619084
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Apoptosis R-HSA-109581
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Innate Immune System R-HSA-168249
Mitotic Metaphase and Anaphase R-HSA-2555396
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
Disorders of transmembrane transporters R-HSA-5619115
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
Immune System R-HSA-168256
MAPK family signaling cascades R-HSA-5683057
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of RNA R-HSA-8953854
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
M Phase R-HSA-68886
Transport of small molecules R-HSA-382551
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vpu mediated degradation of CD4 R-HSA-180534
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants abrogate ligand secretion R-HSA-5387390
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog ligand biogenesis R-HSA-5358346
Neddylation R-HSA-8951664
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
Cellular responses to stimuli R-HSA-8953897
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
MAPK1/MAPK3 signaling R-HSA-5684996
ER-Phagosome pathway R-HSA-1236974
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
PIP3 activates AKT signaling R-HSA-1257604
HIV Infection R-HSA-162906
Signaling by WNT R-HSA-195721
G2/M Checkpoints R-HSA-69481
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Disease R-HSA-1643685
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of Apoptosis R-HSA-169911
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Deubiquitination R-HSA-5688426
Nervous system development R-HSA-9675108
Activation of NF-kappaB in B cells R-HSA-1169091
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of AXIN R-HSA-4641257
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle, Mitotic R-HSA-69278
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Synthesis of DNA R-HSA-69239
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Signaling by Interleukins R-HSA-449147
Signaling by NOTCH R-HSA-157118
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
Stabilization of p53 R-HSA-69541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PCP/CE pathway R-HSA-4086400
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
DNA Replication R-HSA-69306
Signaling by NOTCH4 R-HSA-9013694
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by the B Cell Receptor (BCR) R-HSA-983705
DNA Replication Pre-Initiation R-HSA-69002
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular responses to stress R-HSA-2262752
Separation of Sister Chromatids R-HSA-2467813
Cellular response to chemical stress R-HSA-9711123
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
Hedgehog 'on' state R-HSA-5632684
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
NIK-->noncanonical NF-kB signaling R-HSA-5676590
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by ROBO receptors R-HSA-376176
Metabolism of polyamines R-HSA-351202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX1 R-HSA-8878171
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Negative regulation of NOTCH4 signaling R-HSA-9604323
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Programmed Cell Death R-HSA-5357801
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of proteins R-HSA-392499
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to hypoxia R-HSA-1234174
Nuclear events mediated by NFE2L2 R-HSA-9759194
Neddylation R-HSA-8951664
Hedgehog 'on' state R-HSA-5632684
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RAS by GAPs R-HSA-5658442
DNA Replication R-HSA-69306
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation by RUNX2 R-HSA-8878166
Negative regulation of NOTCH4 signaling R-HSA-9604323
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hh mutants are degraded by ERAD R-HSA-5362768
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle, Mitotic R-HSA-69278
PCP/CE pathway R-HSA-4086400
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of Apoptosis R-HSA-169911
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic G2-G2/M phases R-HSA-453274
G2/M Transition R-HSA-69275
Switching of origins to a post-replicative state R-HSA-69052
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ER-Phagosome pathway R-HSA-1236974
Innate Immune System R-HSA-168249
Post-translational protein modification R-HSA-597592
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK family signaling cascades R-HSA-5683057
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M Checkpoints R-HSA-69481
Regulation of RUNX2 expression and activity R-HSA-8939902
Cytokine Signaling in Immune system R-HSA-1280215
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
C-type lectin receptors (CLRs) R-HSA-5621481
M Phase R-HSA-68886
Beta-catenin independent WNT signaling R-HSA-3858494
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Antigen processing-Cross presentation R-HSA-1236975
p53-Independent DNA Damage Response R-HSA-69610
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Synthesis of DNA R-HSA-69239
DNA Replication Pre-Initiation R-HSA-69002
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
Signaling by WNT R-HSA-195721
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Disorders of transmembrane transporters R-HSA-5619115
KEAP1-NFE2L2 pathway R-HSA-9755511
Deubiquitination R-HSA-5688426
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle Checkpoints R-HSA-69620
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Intracellular signaling by second messengers R-HSA-9006925
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Adaptive Immune System R-HSA-1280218
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of RNA R-HSA-8953854
Cellular responses to stimuli R-HSA-8953897
Degradation of DVL R-HSA-4641258
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic Anaphase R-HSA-68882
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
FCERI mediated NF-kB activation R-HSA-2871837
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog ligand biogenesis R-HSA-5358346
RAF/MAP kinase cascade R-HSA-5673001
Regulation of PTEN stability and activity R-HSA-8948751
Developmental Biology R-HSA-1266738
Cellular response to chemical stress R-HSA-9711123
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Apoptosis R-HSA-109581
Immune System R-HSA-168256
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle R-HSA-1640170
TCR signaling R-HSA-202403
Signaling by the B Cell Receptor (BCR) R-HSA-983705
HIV Infection R-HSA-162906
Regulation of RUNX3 expression and activity R-HSA-8941858
PTEN Regulation R-HSA-6807070
Metabolism R-HSA-1430728
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ub-specific processing proteases R-HSA-5689880
Signaling by Hedgehog R-HSA-5358351
Regulation of mitotic cell cycle R-HSA-453276
Signaling by NOTCH4 R-HSA-9013694
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signal Transduction R-HSA-162582
Signaling by ROBO receptors R-HSA-376176
PIP3 activates AKT signaling R-HSA-1257604
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Host Interactions of HIV factors R-HSA-162909
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of amino acids and derivatives R-HSA-71291
Programmed Cell Death R-HSA-5357801
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
CLEC7A (Dectin-1) signaling R-HSA-5607764
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by ROBO receptors R-HSA-376176
ABC-family proteins mediated transport R-HSA-382556
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to chemical stress R-HSA-9711123
Immune System R-HSA-168256
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RAS by GAPs R-HSA-5658442
G2/M Transition R-HSA-69275
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism R-HSA-1430728
Hedgehog ligand biogenesis R-HSA-5358346
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Infectious disease R-HSA-5663205
MAPK6/MAPK4 signaling R-HSA-5687128
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
Interleukin-1 signaling R-HSA-9020702
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of polyamines R-HSA-351202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'off' state R-HSA-5610787
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of amino acids and derivatives R-HSA-71291
G1/S Transition R-HSA-69206
TCR signaling R-HSA-202403
Cellular responses to stress R-HSA-2262752
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Disease R-HSA-1643685
G2/M Checkpoints R-HSA-69481
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
ABC transporter disorders R-HSA-5619084
Separation of Sister Chromatids R-HSA-2467813
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G1 phase and G1/S transition R-HSA-453279
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Programmed Cell Death R-HSA-5357801
M Phase R-HSA-68886
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
Cellular response to hypoxia R-HSA-1234174
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX1 R-HSA-8878171
Neddylation R-HSA-8951664
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Host Interactions of HIV factors R-HSA-162909
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
PCP/CE pathway R-HSA-4086400
Antigen processing-Cross presentation R-HSA-1236975
Asymmetric localization of PCP proteins R-HSA-4608870
Apoptosis R-HSA-109581
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Innate Immune System R-HSA-168249
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
Transcriptional regulation by RUNX3 R-HSA-8878159
Intracellular signaling by second messengers R-HSA-9006925
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Axon guidance R-HSA-422475
S Phase R-HSA-69242
Signaling by WNT R-HSA-195721
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of RNA R-HSA-8953854
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Stabilization of p53 R-HSA-69541
Switching of origins to a post-replicative state R-HSA-69052
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of AXIN R-HSA-4641257
Vif-mediated degradation of APOBEC3G R-HSA-180585
Defective CFTR causes cystic fibrosis R-HSA-5678895
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
PTEN Regulation R-HSA-6807070
Adaptive Immune System R-HSA-1280218
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX2 R-HSA-8878166
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cyclin E associated events during G1/S transition R-HSA-69202
Activation of NF-kappaB in B cells R-HSA-1169091
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Disease R-HSA-1643685
Asymmetric localization of PCP proteins R-HSA-4608870
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Transition R-HSA-69275
ABC-family proteins mediated transport R-HSA-382556
DNA Replication R-HSA-69306
Regulation of RAS by GAPs R-HSA-5658442
Regulation of RUNX2 expression and activity R-HSA-8939902
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Programmed Cell Death R-HSA-5357801
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent DNA Damage Response R-HSA-69610
Innate Immune System R-HSA-168249
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Beta-catenin independent WNT signaling R-HSA-3858494
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Synthesis of DNA R-HSA-69239
Signaling by Hedgehog R-HSA-5358351
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication Pre-Initiation R-HSA-69002
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCR signaling R-HSA-202403
Defective CFTR causes cystic fibrosis R-HSA-5678895
Apoptosis R-HSA-109581
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular response to chemical stress R-HSA-9711123
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Post-translational protein modification R-HSA-597592
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK family signaling cascades R-HSA-5683057
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stress R-HSA-2262752
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'on' state R-HSA-5632684
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
M Phase R-HSA-68886
Immune System R-HSA-168256
Gene expression (Transcription) R-HSA-74160
S Phase R-HSA-69242
Adaptive Immune System R-HSA-1280218
G2/M Checkpoints R-HSA-69481
Negative regulation of NOTCH4 signaling R-HSA-9604323
RNA Polymerase II Transcription R-HSA-73857
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
HIV Infection R-HSA-162906
Cell Cycle R-HSA-1640170
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Interleukins R-HSA-449147
CLEC7A (Dectin-1) signaling R-HSA-5607764
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Downstream TCR signaling R-HSA-202424
Metabolism of polyamines R-HSA-351202
Regulation of PTEN stability and activity R-HSA-8948751
Infectious disease R-HSA-5663205
Interleukin-1 signaling R-HSA-9020702
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mitotic cell cycle R-HSA-453276
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
Generic Transcription Pathway R-HSA-212436
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hedgehog 'off' state R-HSA-5610787
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Separation of Sister Chromatids R-HSA-2467813
Degradation of DVL R-HSA-4641258
Metabolism of RNA R-HSA-8953854
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of proteins R-HSA-392499
Metabolism of amino acids and derivatives R-HSA-71291
PCP/CE pathway R-HSA-4086400
Transport of small molecules R-HSA-382551
Vpu mediated degradation of CD4 R-HSA-180534
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G2-G2/M phases R-HSA-453274
Neddylation R-HSA-8951664
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism R-HSA-1430728
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing-Cross presentation R-HSA-1236975
Nervous system development R-HSA-9675108
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
C-type lectin receptors (CLRs) R-HSA-5621481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Host Interactions of HIV factors R-HSA-162909
Disorders of transmembrane transporters R-HSA-5619115
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle Checkpoints R-HSA-69620
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic Anaphase R-HSA-68882
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1 DNA Damage Response R-HSA-69563
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RNA Polymerase II Transcription R-HSA-73857
Orc1 removal from chromatin R-HSA-68949
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Nuclear events mediated by NFE2L2 R-HSA-9759194
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of AXIN R-HSA-4641257
Cell Cycle R-HSA-1640170
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by ROBO receptors R-HSA-376176
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to hypoxia R-HSA-1234174
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication Pre-Initiation R-HSA-69002
ABC transporter disorders R-HSA-5619084
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Infectious disease R-HSA-5663205
Metabolism of RNA R-HSA-8953854
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
DNA Replication R-HSA-69306
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PTEN Regulation R-HSA-6807070
Synthesis of DNA R-HSA-69239
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Post-translational protein modification R-HSA-597592
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
Metabolism R-HSA-1430728
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle, Mitotic R-HSA-69278
Signaling by NOTCH R-HSA-157118
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog ligand biogenesis R-HSA-5358346
Programmed Cell Death R-HSA-5357801
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
Disorders of transmembrane transporters R-HSA-5619115
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic Anaphase R-HSA-68882
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transport of small molecules R-HSA-382551
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
G1/S Transition R-HSA-69206
Interleukin-1 family signaling R-HSA-446652
Regulation of mitotic cell cycle R-HSA-453276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of beta-catenin by the destruction complex R-HSA-195253
Separation of Sister Chromatids R-HSA-2467813
Regulation of RUNX3 expression and activity R-HSA-8941858
ER-Phagosome pathway R-HSA-1236974
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK1/MAPK3 signaling R-HSA-5684996
HIV Infection R-HSA-162906
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'off' state R-HSA-5610787
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Apoptosis R-HSA-109581
Intracellular signaling by second messengers R-HSA-9006925
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Assembly of the pre-replicative complex R-HSA-68867
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
G2/M Checkpoints R-HSA-69481
CLEC7A (Dectin-1) signaling R-HSA-5607764
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RAS by GAPs R-HSA-5658442
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX2 R-HSA-8878166
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle Checkpoints R-HSA-69620
MAPK family signaling cascades R-HSA-5683057
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
Regulation of Apoptosis R-HSA-169911
PCP/CE pathway R-HSA-4086400
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Disease R-HSA-1643685
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Independent DNA Damage Response R-HSA-69610
Axon guidance R-HSA-422475
Mitotic G2-G2/M phases R-HSA-453274
RAF/MAP kinase cascade R-HSA-5673001
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stress R-HSA-2262752
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
Adaptive Immune System R-HSA-1280218
Deubiquitination R-HSA-5688426
Innate Immune System R-HSA-168249
Metabolism of polyamines R-HSA-351202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202

Expression Atlas ENSG00000159377
NCBI gene (formerly Entrezgene) 5692
GeneCards 9541
HGNC Symbol HGNC:9541
MIM gene 602177
MIM morbid 617591
UniProtKB Gene Name P28070
WikiGene 5692
Gene: PSMD6
Ensembl ID : ENSG00000163636
Description: proteasome 26S subunit, non-ATPase 6
Gene Synonyms: KIAA0107,P44S10,RPN7,S10
5 APIs:
212 Possible Orthologues:

Cellular responses to stress R-HSA-2262752
DNA Replication R-HSA-69306
G2/M Checkpoints R-HSA-69481
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of RNA R-HSA-8953854
Beta-catenin independent WNT signaling R-HSA-3858494
G2/M Checkpoints R-HSA-69481
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent DNA Damage Response R-HSA-69610
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism R-HSA-1430728
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 signaling R-HSA-9020702
Apoptosis R-HSA-109581
Cell Cycle, Mitotic R-HSA-69278
Regulation of RAS by GAPs R-HSA-5658442
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
UCH proteinases R-HSA-5689603
ER-Phagosome pathway R-HSA-1236974
Neutrophil degranulation R-HSA-6798695
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of Apoptosis R-HSA-169911
Separation of Sister Chromatids R-HSA-2467813
Metabolism of polyamines R-HSA-351202
Hh mutants are degraded by ERAD R-HSA-5362768
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH4 R-HSA-9013694
Signaling by ROBO receptors R-HSA-376176
Post-translational protein modification R-HSA-597592
TCR signaling R-HSA-202403
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PTEN Regulation R-HSA-6807070
Degradation of beta-catenin by the destruction complex R-HSA-195253
Disorders of transmembrane transporters R-HSA-5619115
S Phase R-HSA-69242
Switching of origins to a post-replicative state R-HSA-69052
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Host Interactions of HIV factors R-HSA-162909
DNA Replication Pre-Initiation R-HSA-69002
TCF dependent signaling in response to WNT R-HSA-201681
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of DVL R-HSA-4641258
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle Checkpoints R-HSA-69620
DNA Replication R-HSA-69306
G1/S DNA Damage Checkpoints R-HSA-69615
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Activation of NF-kappaB in B cells R-HSA-1169091
Hedgehog 'off' state R-HSA-5610787
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of PTEN stability and activity R-HSA-8948751
C-type lectin receptors (CLRs) R-HSA-5621481
ABC transporter disorders R-HSA-5619084
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Orc1 removal from chromatin R-HSA-68949
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
Mitotic G1 phase and G1/S transition R-HSA-453279
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Gene expression (Transcription) R-HSA-74160
Cellular response to chemical stress R-HSA-9711123
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transport of small molecules R-HSA-382551
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Adaptive Immune System R-HSA-1280218
Developmental Biology R-HSA-1266738
PCP/CE pathway R-HSA-4086400
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic G2-G2/M phases R-HSA-453274
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
Regulation of RUNX3 expression and activity R-HSA-8941858
Infectious disease R-HSA-5663205
Degradation of AXIN R-HSA-4641257
Metabolism of proteins R-HSA-392499
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Vpu mediated degradation of CD4 R-HSA-180534
Cellular responses to stimuli R-HSA-8953897
Hedgehog ligand biogenesis R-HSA-5358346
M Phase R-HSA-68886
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle R-HSA-1640170
Defective CFTR causes cystic fibrosis R-HSA-5678895
Neddylation R-HSA-8951664
Signal Transduction R-HSA-162582
Interleukin-1 family signaling R-HSA-446652
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI2 by the proteasome R-HSA-5610783
PIP3 activates AKT signaling R-HSA-1257604
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Interleukins R-HSA-449147
Hedgehog 'on' state R-HSA-5632684
Stabilization of p53 R-HSA-69541
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Programmed Cell Death R-HSA-5357801
G2/M Transition R-HSA-69275
Asymmetric localization of PCP proteins R-HSA-4608870
Disease R-HSA-1643685
Downstream TCR signaling R-HSA-202424
Innate Immune System R-HSA-168249
CLEC7A (Dectin-1) signaling R-HSA-5607764
Ub-specific processing proteases R-HSA-5689880
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK family signaling cascades R-HSA-5683057
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Signaling by NOTCH R-HSA-157118
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX2 R-HSA-8878166
RNA Polymerase II Transcription R-HSA-73857
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Immune System R-HSA-168256
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cyclin E associated events during G1/S transition R-HSA-69202
Deubiquitination R-HSA-5688426
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX3 R-HSA-8878159
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic G2-G2/M phases R-HSA-453274
Vif-mediated degradation of APOBEC3G R-HSA-180585
PIP3 activates AKT signaling R-HSA-1257604
Assembly of the pre-replicative complex R-HSA-68867
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of Apoptosis R-HSA-169911
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
TCR signaling R-HSA-202403
Ub-specific processing proteases R-HSA-5689880
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disorders of transmembrane transporters R-HSA-5619115
Intracellular signaling by second messengers R-HSA-9006925
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 signaling R-HSA-9020702
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Degradation of GLI1 by the proteasome R-HSA-5610780
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
CLEC7A (Dectin-1) signaling R-HSA-5607764
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular responses to stress R-HSA-2262752
Metabolism R-HSA-1430728
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Neddylation R-HSA-8951664
Hedgehog ligand biogenesis R-HSA-5358346
Transport of small molecules R-HSA-382551
Signaling by NOTCH R-HSA-157118
Activation of NF-kappaB in B cells R-HSA-1169091
G2/M Checkpoints R-HSA-69481
Switching of origins to a post-replicative state R-HSA-69052
Infectious disease R-HSA-5663205
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'off' state R-HSA-5610787
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Axon guidance R-HSA-422475
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Beta-catenin independent WNT signaling R-HSA-3858494
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by WNT R-HSA-195721
Immune System R-HSA-168256
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Mitotic Anaphase R-HSA-68882
Developmental Biology R-HSA-1266738
Regulation of PTEN stability and activity R-HSA-8948751
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
Class I MHC mediated antigen processing & presentation R-HSA-983169
Separation of Sister Chromatids R-HSA-2467813
UCH proteinases R-HSA-5689603
Neutrophil degranulation R-HSA-6798695
Hedgehog 'on' state R-HSA-5632684
Signaling by ROBO receptors R-HSA-376176
ABC-family proteins mediated transport R-HSA-382556
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Signaling by Hedgehog R-HSA-5358351
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Adaptive Immune System R-HSA-1280218
PTEN Regulation R-HSA-6807070
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
TCF dependent signaling in response to WNT R-HSA-201681
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RNA Polymerase II Transcription R-HSA-73857
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK family signaling cascades R-HSA-5683057
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to hypoxia R-HSA-1234174
HIV Infection R-HSA-162906
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of RNA R-HSA-8953854
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Stabilization of p53 R-HSA-69541
G1/S DNA Damage Checkpoints R-HSA-69615
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle, Mitotic R-HSA-69278
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of GLI2 by the proteasome R-HSA-5610783
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent DNA Damage Response R-HSA-69610
PCP/CE pathway R-HSA-4086400
Innate Immune System R-HSA-168249
S Phase R-HSA-69242
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
Apoptosis R-HSA-109581
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of RUNX3 expression and activity R-HSA-8941858
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of AXIN R-HSA-4641257
Gene expression (Transcription) R-HSA-74160
Antigen processing-Cross presentation R-HSA-1236975
Cellular response to chemical stress R-HSA-9711123
Signaling by Interleukins R-HSA-449147
Post-translational protein modification R-HSA-597592
FCERI mediated NF-kB activation R-HSA-2871837
Defective CFTR causes cystic fibrosis R-HSA-5678895
RAF/MAP kinase cascade R-HSA-5673001
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Programmed Cell Death R-HSA-5357801
Metabolism of polyamines R-HSA-351202
Regulation of RAS by GAPs R-HSA-5658442
M Phase R-HSA-68886
Regulation of mitotic cell cycle R-HSA-453276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G2/M Transition R-HSA-69275
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX3 R-HSA-8878159
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Nuclear events mediated by NFE2L2 R-HSA-9759194
Host Interactions of HIV factors R-HSA-162909
Metabolism of proteins R-HSA-392499
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of Apoptosis R-HSA-169911
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
UCH proteinases R-HSA-5689603
Asymmetric localization of PCP proteins R-HSA-4608870
Neddylation R-HSA-8951664
Hedgehog 'off' state R-HSA-5610787
Antigen processing-Cross presentation R-HSA-1236975
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Signaling by NOTCH R-HSA-157118
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle Checkpoints R-HSA-69620
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of mitotic cell cycle R-HSA-453276
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transcriptional regulation by RUNX2 R-HSA-8878166
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Adaptive Immune System R-HSA-1280218
RNA Polymerase II Transcription R-HSA-73857
Deubiquitination R-HSA-5688426
Interleukin-1 signaling R-HSA-9020702
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by ROBO receptors R-HSA-376176
CLEC7A (Dectin-1) signaling R-HSA-5607764
PIP3 activates AKT signaling R-HSA-1257604
Activation of NF-kappaB in B cells R-HSA-1169091
Post-translational protein modification R-HSA-597592
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RUNX2 expression and activity R-HSA-8939902
Cytokine Signaling in Immune system R-HSA-1280215
Downstream TCR signaling R-HSA-202424
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of polyamines R-HSA-351202
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of RNA R-HSA-8953854
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by Interleukins R-HSA-449147
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of amino acids and derivatives R-HSA-71291
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle R-HSA-1640170
Signaling by WNT R-HSA-195721
Infectious disease R-HSA-5663205
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Neutrophil degranulation R-HSA-6798695
p53-Independent DNA Damage Response R-HSA-69610
Negative regulation of NOTCH4 signaling R-HSA-9604323
Mitotic Metaphase and Anaphase R-HSA-2555396
TCR signaling R-HSA-202403
Hedgehog 'on' state R-HSA-5632684
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
ABC transporter disorders R-HSA-5619084
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stress R-HSA-2262752
Regulation of PTEN stability and activity R-HSA-8948751
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Disorders of transmembrane transporters R-HSA-5619115
Developmental Biology R-HSA-1266738
MAPK6/MAPK4 signaling R-HSA-5687128
Innate Immune System R-HSA-168249
Degradation of DVL R-HSA-4641258
Transport of small molecules R-HSA-382551
FCERI mediated NF-kB activation R-HSA-2871837
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX3 R-HSA-8878159
Gene expression (Transcription) R-HSA-74160
Cellular response to chemical stress R-HSA-9711123
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Programmed Cell Death R-HSA-5357801
Metabolism R-HSA-1430728
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Interleukin-1 family signaling R-HSA-446652
Generic Transcription Pathway R-HSA-212436
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
G2/M Checkpoints R-HSA-69481
p53-Dependent G1 DNA Damage Response R-HSA-69563
Separation of Sister Chromatids R-HSA-2467813
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
TCF dependent signaling in response to WNT R-HSA-201681
ABC-family proteins mediated transport R-HSA-382556
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Host Interactions of HIV factors R-HSA-162909
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ER-Phagosome pathway R-HSA-1236974
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle, Mitotic R-HSA-69278
Orc1 removal from chromatin R-HSA-68949
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Apoptosis R-HSA-109581
PCP/CE pathway R-HSA-4086400
G1/S Transition R-HSA-69206
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Intracellular signaling by second messengers R-HSA-9006925
S Phase R-HSA-69242
Class I MHC mediated antigen processing & presentation R-HSA-983169
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G2/M Transition R-HSA-69275
Mitotic Anaphase R-HSA-68882
Regulation of RAS by GAPs R-HSA-5658442
HIV Infection R-HSA-162906
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin E associated events during G1/S transition R-HSA-69202
Stabilization of p53 R-HSA-69541
Hedgehog ligand biogenesis R-HSA-5358346
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI1 by the proteasome R-HSA-5610780
Ub-specific processing proteases R-HSA-5689880
Degradation of AXIN R-HSA-4641257
Vpu mediated degradation of CD4 R-HSA-180534
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Interleukin-1 signaling R-HSA-9020702
Metabolism of RNA R-HSA-8953854
RAF/MAP kinase cascade R-HSA-5673001
Innate Immune System R-HSA-168249
MAPK6/MAPK4 signaling R-HSA-5687128
HIV Infection R-HSA-162906
RNA Polymerase II Transcription R-HSA-73857
Mitotic Anaphase R-HSA-68882
G1/S DNA Damage Checkpoints R-HSA-69615
Programmed Cell Death R-HSA-5357801
Infectious disease R-HSA-5663205
Cellular response to hypoxia R-HSA-1234174
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PCP/CE pathway R-HSA-4086400
Assembly of the pre-replicative complex R-HSA-68867
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Disease R-HSA-1643685
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 family signaling R-HSA-446652
Degradation of GLI2 by the proteasome R-HSA-5610783
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by ROBO receptors R-HSA-376176
Metabolism of amino acids and derivatives R-HSA-71291
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G2/M Checkpoints R-HSA-69481
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX3 R-HSA-8878159
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of polyamines R-HSA-351202
Ub-specific processing proteases R-HSA-5689880
Downstream TCR signaling R-HSA-202424
Post-translational protein modification R-HSA-597592
Signal Transduction R-HSA-162582
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX3 expression and activity R-HSA-8941858
PTEN Regulation R-HSA-6807070
Regulation of RAS by GAPs R-HSA-5658442
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Axon guidance R-HSA-422475
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCF dependent signaling in response to WNT R-HSA-201681
Intracellular signaling by second messengers R-HSA-9006925
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Vif-mediated degradation of APOBEC3G R-HSA-180585
G1/S Transition R-HSA-69206
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic G1 phase and G1/S transition R-HSA-453279
Orc1 removal from chromatin R-HSA-68949
Antigen processing-Cross presentation R-HSA-1236975
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog 'on' state R-HSA-5632684
Defective CFTR causes cystic fibrosis R-HSA-5678895
Host Interactions of HIV factors R-HSA-162909
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ABC transporter disorders R-HSA-5619084
Neutrophil degranulation R-HSA-6798695
G2/M Transition R-HSA-69275
Deubiquitination R-HSA-5688426
Degradation of DVL R-HSA-4641258
Cellular response to chemical stress R-HSA-9711123
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nervous system development R-HSA-9675108
Adaptive Immune System R-HSA-1280218
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by NOTCH R-HSA-157118
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
Transport of small molecules R-HSA-382551
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
KEAP1-NFE2L2 pathway R-HSA-9755511
Separation of Sister Chromatids R-HSA-2467813
Signaling by NOTCH4 R-HSA-9013694
Mitotic G2-G2/M phases R-HSA-453274
PIP3 activates AKT signaling R-HSA-1257604
M Phase R-HSA-68886
Developmental Biology R-HSA-1266738
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Vpu mediated degradation of CD4 R-HSA-180534
Disorders of transmembrane transporters R-HSA-5619115
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by WNT R-HSA-195721
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Apoptosis R-HSA-109581
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog ligand biogenesis R-HSA-5358346
MAPK family signaling cascades R-HSA-5683057
Metabolism of proteins R-HSA-392499
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of Apoptosis R-HSA-169911
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
S Phase R-HSA-69242
Cytokine Signaling in Immune system R-HSA-1280215
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Activation of NF-kappaB in B cells R-HSA-1169091
Switching of origins to a post-replicative state R-HSA-69052
Regulation of PTEN stability and activity R-HSA-8948751
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell Cycle Checkpoints R-HSA-69620
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle R-HSA-1640170
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
DNA Replication Pre-Initiation R-HSA-69002
TCR signaling R-HSA-202403
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
p53-Independent DNA Damage Response R-HSA-69610
Synthesis of DNA R-HSA-69239
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Class I MHC mediated antigen processing & presentation R-HSA-983169
Asymmetric localization of PCP proteins R-HSA-4608870
ER-Phagosome pathway R-HSA-1236974
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
ABC-family proteins mediated transport R-HSA-382556
Immune System R-HSA-168256
Signaling by Hedgehog R-HSA-5358351
DNA Replication R-HSA-69306
Signaling by Interleukins R-HSA-449147
CLEC7A (Dectin-1) signaling R-HSA-5607764
Asymmetric localization of PCP proteins R-HSA-4608870
HIV Infection R-HSA-162906
Signaling by NOTCH4 R-HSA-9013694
Neutrophil degranulation R-HSA-6798695
Programmed Cell Death R-HSA-5357801
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of DNA R-HSA-69239
Cellular responses to stimuli R-HSA-8953897
Neddylation R-HSA-8951664
Intracellular signaling by second messengers R-HSA-9006925
G2/M Checkpoints R-HSA-69481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Anaphase R-HSA-68882
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Vpu mediated degradation of CD4 R-HSA-180534
MAPK family signaling cascades R-HSA-5683057
Signaling by WNT R-HSA-195721
Mitotic Metaphase and Anaphase R-HSA-2555396
Transport of small molecules R-HSA-382551
Developmental Biology R-HSA-1266738
Regulation of RUNX2 expression and activity R-HSA-8939902
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX3 R-HSA-8878159
Signal Transduction R-HSA-162582
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog ligand biogenesis R-HSA-5358346
ABC-family proteins mediated transport R-HSA-382556
Negative regulation of NOTCH4 signaling R-HSA-9604323
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of beta-catenin by the destruction complex R-HSA-195253
Mitotic G2-G2/M phases R-HSA-453274
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK1/MAPK3 signaling R-HSA-5684996
Nervous system development R-HSA-9675108
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism R-HSA-1430728
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'off' state R-HSA-5610787
Downstream TCR signaling R-HSA-202424
Separation of Sister Chromatids R-HSA-2467813
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of DVL R-HSA-4641258
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G1 phase and G1/S transition R-HSA-453279
Antigen processing-Cross presentation R-HSA-1236975
Regulation of mitotic cell cycle R-HSA-453276
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Stabilization of p53 R-HSA-69541
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Regulation of Apoptosis R-HSA-169911
Regulation of PTEN stability and activity R-HSA-8948751
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Host Interactions of HIV factors R-HSA-162909
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of polyamines R-HSA-351202
Transcriptional regulation by RUNX1 R-HSA-8878171
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular response to hypoxia R-HSA-1234174
Cell Cycle Checkpoints R-HSA-69620
Immune System R-HSA-168256
PCP/CE pathway R-HSA-4086400
Signaling by NOTCH R-HSA-157118
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
CLEC7A (Dectin-1) signaling R-HSA-5607764
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Defective CFTR causes cystic fibrosis R-HSA-5678895
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of RAS by GAPs R-HSA-5658442
PIP3 activates AKT signaling R-HSA-1257604
G2/M Transition R-HSA-69275
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cyclin E associated events during G1/S transition R-HSA-69202
Ub-specific processing proteases R-HSA-5689880
Signaling by Hedgehog R-HSA-5358351
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Activation of NF-kappaB in B cells R-HSA-1169091
Axon guidance R-HSA-422475
DNA Replication R-HSA-69306
UCH proteinases R-HSA-5689603
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 signaling R-HSA-9020702
Metabolism of RNA R-HSA-8953854
Post-translational protein modification R-HSA-597592
TCR signaling R-HSA-202403
Adaptive Immune System R-HSA-1280218
S Phase R-HSA-69242
Assembly of the pre-replicative complex R-HSA-68867
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-1 family signaling R-HSA-446652
Cellular response to chemical stress R-HSA-9711123
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vif-mediated degradation of APOBEC3G R-HSA-180585
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of AXIN R-HSA-4641257
ER-Phagosome pathway R-HSA-1236974
Metabolism of proteins R-HSA-392499
Beta-catenin independent WNT signaling R-HSA-3858494
G1/S Transition R-HSA-69206
ABC transporter disorders R-HSA-5619084
Cellular responses to stress R-HSA-2262752
DNA Replication Pre-Initiation R-HSA-69002
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Innate Immune System R-HSA-168249
Disorders of transmembrane transporters R-HSA-5619115
Class I MHC mediated antigen processing & presentation R-HSA-983169
Apoptosis R-HSA-109581
Metabolism of amino acids and derivatives R-HSA-71291
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hedgehog 'on' state R-HSA-5632684
Switching of origins to a post-replicative state R-HSA-69052
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle, Mitotic R-HSA-69278
Metabolism of polyamines R-HSA-351202
Degradation of AXIN R-HSA-4641257
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX1 R-HSA-8878171
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing-Cross presentation R-HSA-1236975
Regulation of PTEN stability and activity R-HSA-8948751
ABC-family proteins mediated transport R-HSA-382556
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Mitotic Anaphase R-HSA-68882
Signaling by WNT R-HSA-195721
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of DVL R-HSA-4641258
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of RUNX3 expression and activity R-HSA-8941858
Nervous system development R-HSA-9675108
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'on' state R-HSA-5632684
DNA Replication R-HSA-69306
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation by RUNX3 R-HSA-8878159
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
Axon guidance R-HSA-422475
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
Regulation of RUNX2 expression and activity R-HSA-8939902
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ub-specific processing proteases R-HSA-5689880
Cellular response to chemical stress R-HSA-9711123
Mitotic G2-G2/M phases R-HSA-453274
Interleukin-1 signaling R-HSA-9020702
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Deubiquitination R-HSA-5688426
TCF dependent signaling in response to WNT R-HSA-201681
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of proteins R-HSA-392499
G2/M Checkpoints R-HSA-69481
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
TCR signaling R-HSA-202403
Transport of small molecules R-HSA-382551
Cellular response to hypoxia R-HSA-1234174
Regulation of RAS by GAPs R-HSA-5658442
Nuclear events mediated by NFE2L2 R-HSA-9759194
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent DNA Damage Response R-HSA-69610
Host Interactions of HIV factors R-HSA-162909
C-type lectin receptors (CLRs) R-HSA-5621481
Infectious disease R-HSA-5663205
Separation of Sister Chromatids R-HSA-2467813
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
G1/S Transition R-HSA-69206
Developmental Biology R-HSA-1266738
Apoptosis R-HSA-109581
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by NOTCH4 R-HSA-9013694
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK1/MAPK3 signaling R-HSA-5684996
HIV Infection R-HSA-162906
PTEN Regulation R-HSA-6807070
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Intracellular signaling by second messengers R-HSA-9006925
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Metaphase and Anaphase R-HSA-2555396
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Disorders of transmembrane transporters R-HSA-5619115
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of mitotic cell cycle R-HSA-453276
Defective CFTR causes cystic fibrosis R-HSA-5678895
RNA Polymerase II Transcription R-HSA-73857
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Dependent G1 DNA Damage Response R-HSA-69563
Synthesis of DNA R-HSA-69239
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
CLEC7A (Dectin-1) signaling R-HSA-5607764
ABC transporter disorders R-HSA-5619084
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Innate Immune System R-HSA-168249
Activation of NF-kappaB in B cells R-HSA-1169091
Beta-catenin independent WNT signaling R-HSA-3858494
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Post-translational protein modification R-HSA-597592
Metabolism R-HSA-1430728
FCERI mediated NF-kB activation R-HSA-2871837
Stabilization of p53 R-HSA-69541
Disease R-HSA-1643685
Neddylation R-HSA-8951664
Neutrophil degranulation R-HSA-6798695
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of expression of SLITs and ROBOs R-HSA-9010553
RAF/MAP kinase cascade R-HSA-5673001
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signal Transduction R-HSA-162582
Hh mutants are degraded by ERAD R-HSA-5362768
ER-Phagosome pathway R-HSA-1236974
Signaling by NOTCH R-HSA-157118
PCP/CE pathway R-HSA-4086400
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G2/M Transition R-HSA-69275
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Programmed Cell Death R-HSA-5357801
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Hedgehog R-HSA-5358351
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream TCR signaling R-HSA-202424
Interleukin-1 family signaling R-HSA-446652
Hedgehog 'off' state R-HSA-5610787
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Interleukins R-HSA-449147
M Phase R-HSA-68886
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle R-HSA-1640170
Regulation of Apoptosis R-HSA-169911
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
RNA Polymerase II Transcription R-HSA-73857
Cyclin E associated events during G1/S transition R-HSA-69202
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256
CLEC7A (Dectin-1) signaling R-HSA-5607764
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing-Cross presentation R-HSA-1236975
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of RNA R-HSA-8953854
MAPK family signaling cascades R-HSA-5683057
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of beta-catenin by the destruction complex R-HSA-195253
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle, Mitotic R-HSA-69278
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RUNX2 expression and activity R-HSA-8939902
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX3 R-HSA-8878159
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Anaphase R-HSA-68882
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vpu mediated degradation of CD4 R-HSA-180534
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RAS by GAPs R-HSA-5658442
Interleukin-1 family signaling R-HSA-446652
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G1 phase and G1/S transition R-HSA-453279
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
DNA Replication Pre-Initiation R-HSA-69002
ER-Phagosome pathway R-HSA-1236974
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Adaptive Immune System R-HSA-1280218
Degradation of GLI1 by the proteasome R-HSA-5610780
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of polyamines R-HSA-351202
Cellular response to chemical stress R-HSA-9711123
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of amino acids and derivatives R-HSA-71291
M Phase R-HSA-68886
Cellular responses to stimuli R-HSA-8953897
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 signaling R-HSA-9020702
FCERI mediated NF-kB activation R-HSA-2871837
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by Interleukins R-HSA-449147
Intracellular signaling by second messengers R-HSA-9006925
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RUNX3 expression and activity R-HSA-8941858
Innate Immune System R-HSA-168249
Host Interactions of HIV factors R-HSA-162909
ABC transporter disorders R-HSA-5619084
Disease R-HSA-1643685
Assembly of the pre-replicative complex R-HSA-68867
HIV Infection R-HSA-162906
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Checkpoints R-HSA-69481
Switching of origins to a post-replicative state R-HSA-69052
Vif-mediated degradation of APOBEC3G R-HSA-180585
Post-translational protein modification R-HSA-597592
Developmental Biology R-HSA-1266738
Degradation of AXIN R-HSA-4641257
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hedgehog 'off' state R-HSA-5610787
TCR signaling R-HSA-202403
Metabolism R-HSA-1430728
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by WNT R-HSA-195721
Disorders of transmembrane transporters R-HSA-5619115
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Nervous system development R-HSA-9675108
Degradation of DVL R-HSA-4641258
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH4 R-HSA-9013694
Neutrophil degranulation R-HSA-6798695
Infectious disease R-HSA-5663205
Hedgehog 'on' state R-HSA-5632684
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of Apoptosis R-HSA-169911
Cell Cycle R-HSA-1640170
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transport of small molecules R-HSA-382551
PTEN Regulation R-HSA-6807070
Activation of NF-kappaB in B cells R-HSA-1169091
G1/S Transition R-HSA-69206
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular response to hypoxia R-HSA-1234174
S Phase R-HSA-69242
DNA Replication R-HSA-69306
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
UCH proteinases R-HSA-5689603
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream TCR signaling R-HSA-202424
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PCP/CE pathway R-HSA-4086400
C-type lectin receptors (CLRs) R-HSA-5621481
Asymmetric localization of PCP proteins R-HSA-4608870
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of GLI2 by the proteasome R-HSA-5610783
Neddylation R-HSA-8951664
Deubiquitination R-HSA-5688426
ABC-family proteins mediated transport R-HSA-382556
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Apoptosis R-HSA-109581
Cellular responses to stress R-HSA-2262752
Stabilization of p53 R-HSA-69541
Ub-specific processing proteases R-HSA-5689880
G2/M Transition R-HSA-69275
Synthesis of DNA R-HSA-69239
Beta-catenin independent WNT signaling R-HSA-3858494
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle Checkpoints R-HSA-69620
Regulation of PTEN stability and activity R-HSA-8948751
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of proteins R-HSA-392499
Axon guidance R-HSA-422475
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Programmed Cell Death R-HSA-5357801
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by ROBO receptors R-HSA-376176
Signal Transduction R-HSA-162582
RAF/MAP kinase cascade R-HSA-5673001
Separation of Sister Chromatids R-HSA-2467813
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by Hedgehog R-HSA-5358351
Cytokine Signaling in Immune system R-HSA-1280215
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
TCF dependent signaling in response to WNT R-HSA-201681
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Neutrophil degranulation R-HSA-6798695
NIK-->noncanonical NF-kB signaling R-HSA-5676590
RNA Polymerase II Transcription R-HSA-73857
Signaling by WNT R-HSA-195721
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
C-type lectin receptors (CLRs) R-HSA-5621481
PTEN Regulation R-HSA-6807070
Switching of origins to a post-replicative state R-HSA-69052
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Disease R-HSA-1643685
Post-translational protein modification R-HSA-597592
Vif-mediated degradation of APOBEC3G R-HSA-180585
Activation of NF-kappaB in B cells R-HSA-1169091
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
Degradation of beta-catenin by the destruction complex R-HSA-195253
Separation of Sister Chromatids R-HSA-2467813
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication Pre-Initiation R-HSA-69002
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
Metabolism of RNA R-HSA-8953854
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of proteins R-HSA-392499
Signaling by NOTCH4 R-HSA-9013694
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle, Mitotic R-HSA-69278
PCP/CE pathway R-HSA-4086400
Disorders of transmembrane transporters R-HSA-5619115
Generic Transcription Pathway R-HSA-212436
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ABC-family proteins mediated transport R-HSA-382556
Cellular response to hypoxia R-HSA-1234174
Regulation of RAS by GAPs R-HSA-5658442
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
Stabilization of p53 R-HSA-69541
PIP3 activates AKT signaling R-HSA-1257604
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of polyamines R-HSA-351202
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stress R-HSA-2262752
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Assembly of the pre-replicative complex R-HSA-68867
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle R-HSA-1640170
TCF dependent signaling in response to WNT R-HSA-201681
Transport of small molecules R-HSA-382551
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of DVL R-HSA-4641258
Hedgehog 'on' state R-HSA-5632684
Neddylation R-HSA-8951664
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic Metaphase and Anaphase R-HSA-2555396
Intracellular signaling by second messengers R-HSA-9006925
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hh mutants abrogate ligand secretion R-HSA-5387390
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of Apoptosis R-HSA-169911
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of amino acids and derivatives R-HSA-71291
Synthesis of DNA R-HSA-69239
Ub-specific processing proteases R-HSA-5689880
Orc1 removal from chromatin R-HSA-68949
Innate Immune System R-HSA-168249
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
ABC transporter disorders R-HSA-5619084
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
G2/M Checkpoints R-HSA-69481
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stimuli R-HSA-8953897
Beta-catenin independent WNT signaling R-HSA-3858494
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular response to chemical stress R-HSA-9711123
Infectious disease R-HSA-5663205
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism R-HSA-1430728
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
UCH proteinases R-HSA-5689603
Hedgehog 'off' state R-HSA-5610787
Hedgehog ligand biogenesis R-HSA-5358346
p53-Dependent G1 DNA Damage Response R-HSA-69563
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Asymmetric localization of PCP proteins R-HSA-4608870
CLEC7A (Dectin-1) signaling R-HSA-5607764
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S Transition R-HSA-69206
DNA Replication R-HSA-69306
MAPK family signaling cascades R-HSA-5683057
Mitotic G2-G2/M phases R-HSA-453274
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Apoptosis R-HSA-109581
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vpu mediated degradation of CD4 R-HSA-180534
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of GLI2 by the proteasome R-HSA-5610783
ER-Phagosome pathway R-HSA-1236974
Deubiquitination R-HSA-5688426
Regulation of RUNX2 expression and activity R-HSA-8939902
Downstream TCR signaling R-HSA-202424
Regulation of expression of SLITs and ROBOs R-HSA-9010553
HIV Infection R-HSA-162906
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCR signaling R-HSA-202403
Antigen processing-Cross presentation R-HSA-1236975
Interleukin-1 signaling R-HSA-9020702
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Class I MHC mediated antigen processing & presentation R-HSA-983169
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
Signaling by ROBO receptors R-HSA-376176
p53-Independent DNA Damage Response R-HSA-69610
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX1 R-HSA-8878171
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin E associated events during G1/S transition R-HSA-69202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-1 family signaling R-HSA-446652
Degradation of AXIN R-HSA-4641257
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic Anaphase R-HSA-68882
FCERI mediated NF-kB activation R-HSA-2871837
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signal Transduction R-HSA-162582
Regulation of RUNX3 expression and activity R-HSA-8941858
S Phase R-HSA-69242
M Phase R-HSA-68886
Orc1 removal from chromatin R-HSA-68949
Programmed Cell Death R-HSA-5357801
Mitotic Metaphase and Anaphase R-HSA-2555396
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stimuli R-HSA-8953897
Downstream TCR signaling R-HSA-202424
Cellular response to chemical stress R-HSA-9711123
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by Hedgehog R-HSA-5358351
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Intracellular signaling by second messengers R-HSA-9006925
Generic Transcription Pathway R-HSA-212436
Neutrophil degranulation R-HSA-6798695
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Class I MHC mediated antigen processing & presentation R-HSA-983169
DNA Replication R-HSA-69306
KEAP1-NFE2L2 pathway R-HSA-9755511
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hedgehog 'on' state R-HSA-5632684
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Antigen processing-Cross presentation R-HSA-1236975
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cell Cycle, Mitotic R-HSA-69278
Signaling by NOTCH4 R-HSA-9013694
HIV Infection R-HSA-162906
Metabolism of proteins R-HSA-392499
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
Signaling by WNT R-HSA-195721
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX3 expression and activity R-HSA-8941858
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stress R-HSA-2262752
MAPK6/MAPK4 signaling R-HSA-5687128
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Metabolism of polyamines R-HSA-351202
FCERI mediated NF-kB activation R-HSA-2871837
Developmental Biology R-HSA-1266738
Immune System R-HSA-168256
Beta-catenin independent WNT signaling R-HSA-3858494
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'off' state R-HSA-5610787
Cell Cycle Checkpoints R-HSA-69620
G1/S DNA Damage Checkpoints R-HSA-69615
M Phase R-HSA-68886
Regulation of RAS by GAPs R-HSA-5658442
TCR signaling R-HSA-202403
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX2 expression and activity R-HSA-8939902
Deubiquitination R-HSA-5688426
G2/M Transition R-HSA-69275
Hh mutants abrogate ligand secretion R-HSA-5387390
G1/S Transition R-HSA-69206
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Infectious disease R-HSA-5663205
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Separation of Sister Chromatids R-HSA-2467813
Vpu mediated degradation of CD4 R-HSA-180534
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 family signaling R-HSA-446652
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mitotic cell cycle R-HSA-453276
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PIP3 activates AKT signaling R-HSA-1257604
PTEN Regulation R-HSA-6807070
DNA Replication Pre-Initiation R-HSA-69002
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of Apoptosis R-HSA-169911
Degradation of DVL R-HSA-4641258
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Post-translational protein modification R-HSA-597592
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of RNA R-HSA-8953854
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Dependent G1 DNA Damage Response R-HSA-69563
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
ABC-family proteins mediated transport R-HSA-382556
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by ROBO receptors R-HSA-376176
Nuclear events mediated by NFE2L2 R-HSA-9759194
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of AXIN R-HSA-4641257
Stabilization of p53 R-HSA-69541
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
G2/M Checkpoints R-HSA-69481
Axon guidance R-HSA-422475
ER-Phagosome pathway R-HSA-1236974
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants are degraded by ERAD R-HSA-5362768
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent DNA Damage Response R-HSA-69610
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by NOTCH R-HSA-157118
Interleukin-1 signaling R-HSA-9020702
ABC transporter disorders R-HSA-5619084
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Defective CFTR causes cystic fibrosis R-HSA-5678895
Neddylation R-HSA-8951664
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
MAPK family signaling cascades R-HSA-5683057
S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Assembly of the pre-replicative complex R-HSA-68867
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX1 R-HSA-8878171
Ub-specific processing proteases R-HSA-5689880
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transport of small molecules R-HSA-382551
Synthesis of DNA R-HSA-69239
Metabolism of amino acids and derivatives R-HSA-71291
Cyclin E associated events during G1/S transition R-HSA-69202
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic Anaphase R-HSA-68882
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by Interleukins R-HSA-449147
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of polyamines R-HSA-351202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI2 by the proteasome R-HSA-5610783
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic Anaphase R-HSA-68882
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cyclin E associated events during G1/S transition R-HSA-69202
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
Intracellular signaling by second messengers R-HSA-9006925
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Innate Immune System R-HSA-168249
Hedgehog 'off' state R-HSA-5610787
CLEC7A (Dectin-1) signaling R-HSA-5607764
Adaptive Immune System R-HSA-1280218
KEAP1-NFE2L2 pathway R-HSA-9755511
Post-translational protein modification R-HSA-597592
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK family signaling cascades R-HSA-5683057
Cell Cycle R-HSA-1640170
Regulation of RAS by GAPs R-HSA-5658442
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH4 R-HSA-9013694
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'on' state R-HSA-5632684
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Hedgehog R-HSA-5358351
HIV Infection R-HSA-162906
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-1 signaling R-HSA-9020702
Cell Cycle Checkpoints R-HSA-69620
Neutrophil degranulation R-HSA-6798695
PTEN Regulation R-HSA-6807070
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G2/M Transition R-HSA-69275
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S Transition R-HSA-69206
DNA Replication Pre-Initiation R-HSA-69002
Neddylation R-HSA-8951664
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
Downstream TCR signaling R-HSA-202424
Nuclear events mediated by NFE2L2 R-HSA-9759194
Immune System R-HSA-168256
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX1 R-HSA-8878171
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic G2-G2/M phases R-HSA-453274
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
ER-Phagosome pathway R-HSA-1236974
M Phase R-HSA-68886
Host Interactions of HIV factors R-HSA-162909
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
Disease R-HSA-1643685
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Orc1 removal from chromatin R-HSA-68949
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of proteins R-HSA-392499
Degradation of AXIN R-HSA-4641257
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
UCH proteinases R-HSA-5689603
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX2 R-HSA-8878166
Deubiquitination R-HSA-5688426
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cytokine Signaling in Immune system R-HSA-1280215
DNA Replication R-HSA-69306
Asymmetric localization of PCP proteins R-HSA-4608870
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH R-HSA-157118
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Assembly of the pre-replicative complex R-HSA-68867
Vpu mediated degradation of CD4 R-HSA-180534
RNA Polymerase II Transcription R-HSA-73857
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Stabilization of p53 R-HSA-69541
Cellular response to chemical stress R-HSA-9711123
G1/S DNA Damage Checkpoints R-HSA-69615
Defective CFTR causes cystic fibrosis R-HSA-5678895
TCR signaling R-HSA-202403
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Developmental Biology R-HSA-1266738
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
C-type lectin receptors (CLRs) R-HSA-5621481
Hh mutants abrogate ligand secretion R-HSA-5387390
Transport of small molecules R-HSA-382551
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Synthesis of DNA R-HSA-69239
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent DNA Damage Response R-HSA-69610
Mitotic G1 phase and G1/S transition R-HSA-453279
Disorders of transmembrane transporters R-HSA-5619115
Activation of NF-kappaB in B cells R-HSA-1169091
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stress R-HSA-2262752
Signal Transduction R-HSA-162582
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by Interleukins R-HSA-449147
ABC-family proteins mediated transport R-HSA-382556
Axon guidance R-HSA-422475
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
Nervous system development R-HSA-9675108
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by ROBO receptors R-HSA-376176
Regulation of RUNX2 expression and activity R-HSA-8939902
PCP/CE pathway R-HSA-4086400
Cellular responses to stimuli R-HSA-8953897
Mitotic Metaphase and Anaphase R-HSA-2555396
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX3 R-HSA-8878159
Apoptosis R-HSA-109581
Regulation of Apoptosis R-HSA-169911
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transcriptional regulation by RUNX1 R-HSA-8878171
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
Cellular responses to stimuli R-HSA-8953897
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of polyamines R-HSA-351202
Developmental Biology R-HSA-1266738
ABC transporter disorders R-HSA-5619084
Host Interactions of HIV factors R-HSA-162909
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of amino acids and derivatives R-HSA-71291
Infectious disease R-HSA-5663205
S Phase R-HSA-69242
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK6/MAPK4 signaling R-HSA-5687128
Class I MHC mediated antigen processing & presentation R-HSA-983169
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by ROBO receptors R-HSA-376176
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nervous system development R-HSA-9675108
Regulation of PTEN stability and activity R-HSA-8948751
Deubiquitination R-HSA-5688426
Cyclin E associated events during G1/S transition R-HSA-69202
DNA Replication Pre-Initiation R-HSA-69002
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
Disease R-HSA-1643685
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic G1 phase and G1/S transition R-HSA-453279
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by Interleukins R-HSA-449147
PIP3 activates AKT signaling R-HSA-1257604
Separation of Sister Chromatids R-HSA-2467813
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX2 R-HSA-8878166
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of GLI2 by the proteasome R-HSA-5610783
ABC-family proteins mediated transport R-HSA-382556
M Phase R-HSA-68886
Hh mutants are degraded by ERAD R-HSA-5362768
Cytokine Signaling in Immune system R-HSA-1280215
HIV Infection R-HSA-162906
Disorders of transmembrane transporters R-HSA-5619115
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH4 R-HSA-9013694
Orc1 removal from chromatin R-HSA-68949
Assembly of the pre-replicative complex R-HSA-68867
Regulation of RAS by GAPs R-HSA-5658442
Metabolism R-HSA-1430728
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular response to hypoxia R-HSA-1234174
Negative regulation of NOTCH4 signaling R-HSA-9604323
Generic Transcription Pathway R-HSA-212436
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of Apoptosis R-HSA-169911
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
Hedgehog 'off' state R-HSA-5610787
Regulation of RUNX3 expression and activity R-HSA-8941858
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of DVL R-HSA-4641258
ER-Phagosome pathway R-HSA-1236974
Degradation of GLI1 by the proteasome R-HSA-5610780
Synthesis of DNA R-HSA-69239
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Switching of origins to a post-replicative state R-HSA-69052
Neutrophil degranulation R-HSA-6798695
Downstream TCR signaling R-HSA-202424
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
Neddylation R-HSA-8951664
Cell Cycle R-HSA-1640170
Axon guidance R-HSA-422475
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Post-translational protein modification R-HSA-597592
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of AXIN R-HSA-4641257
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
Gene expression (Transcription) R-HSA-74160
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Innate Immune System R-HSA-168249
Interleukin-1 family signaling R-HSA-446652
Cell Cycle, Mitotic R-HSA-69278
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular responses to stress R-HSA-2262752
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ub-specific processing proteases R-HSA-5689880
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of RNA R-HSA-8953854
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle Checkpoints R-HSA-69620
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Anaphase R-HSA-68882
Nuclear events mediated by NFE2L2 R-HSA-9759194
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Apoptosis R-HSA-109581
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent DNA Damage Response R-HSA-69610
Asymmetric localization of PCP proteins R-HSA-4608870
DNA Replication R-HSA-69306
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signal Transduction R-HSA-162582
Regulation of expression of SLITs and ROBOs R-HSA-9010553
UCH proteinases R-HSA-5689603
TCF dependent signaling in response to WNT R-HSA-201681
Transport of small molecules R-HSA-382551
Stabilization of p53 R-HSA-69541
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684

Expression Atlas ENSG00000163636
NCBI gene (formerly Entrezgene) 9861
GeneCards 9564
HGNC Symbol HGNC:9564
MIM gene 617857
UniProtKB Gene Name Q15008
WikiGene 9861
Gene: PSMC4
Ensembl ID : ENSG00000013275
Description: proteasome 26S subunit, ATPase 4
Gene Synonyms: MGC13687,MGC23214,MGC8570,MIP224,RPT3,S6,TBP-7,TBP7
5 APIs:
199 Possible Orthologues:

Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
Beta-catenin independent WNT signaling R-HSA-3858494
Cell Cycle, Mitotic R-HSA-69278
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX3 R-HSA-8878159
Vpu mediated degradation of CD4 R-HSA-180534
Switching of origins to a post-replicative state R-HSA-69052
Negative regulation of NOTCH4 signaling R-HSA-9604323
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing-Cross presentation R-HSA-1236975
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
RAF/MAP kinase cascade R-HSA-5673001
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Synthesis of DNA R-HSA-69239
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Transition R-HSA-69275
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI1 by the proteasome R-HSA-5610780
Orc1 removal from chromatin R-HSA-68949
ABC transporter disorders R-HSA-5619084
Signaling by WNT R-HSA-195721
Host Interactions of HIV factors R-HSA-162909
Generic Transcription Pathway R-HSA-212436
Ub-specific processing proteases R-HSA-5689880
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of polyamines R-HSA-351202
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
Hh mutants abrogate ligand secretion R-HSA-5387390
Interleukin-1 signaling R-HSA-9020702
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by ROBO receptors R-HSA-376176
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of RUNX2 expression and activity R-HSA-8939902
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Transport of small molecules R-HSA-382551
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of Apoptosis R-HSA-169911
PTEN Regulation R-HSA-6807070
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Apoptosis R-HSA-109581
Degradation of GLI2 by the proteasome R-HSA-5610783
HIV Infection R-HSA-162906
p53-Independent DNA Damage Response R-HSA-69610
G2/M Checkpoints R-HSA-69481
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
Cellular response to chemical stress R-HSA-9711123
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular responses to stress R-HSA-2262752
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PIP3 activates AKT signaling R-HSA-1257604
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of RNA R-HSA-8953854
Innate Immune System R-HSA-168249
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Replication Pre-Initiation R-HSA-69002
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Replication R-HSA-69306
Assembly of the pre-replicative complex R-HSA-68867
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Stabilization of p53 R-HSA-69541
MAPK1/MAPK3 signaling R-HSA-5684996
PCP/CE pathway R-HSA-4086400
Signal Transduction R-HSA-162582
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Nervous system development R-HSA-9675108
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Deubiquitination R-HSA-5688426
Signaling by NOTCH R-HSA-157118
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'on' state R-HSA-5632684
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
S Phase R-HSA-69242
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Separation of Sister Chromatids R-HSA-2467813
Nuclear events mediated by NFE2L2 R-HSA-9759194
Post-translational protein modification R-HSA-597592
Degradation of DVL R-HSA-4641258
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
Disorders of transmembrane transporters R-HSA-5619115
Hedgehog 'off' state R-HSA-5610787
Cell Cycle Checkpoints R-HSA-69620
Cellular response to hypoxia R-HSA-1234174
UCH proteinases R-HSA-5689603
Programmed Cell Death R-HSA-5357801
Cellular responses to stimuli R-HSA-8953897
Cytokine Signaling in Immune system R-HSA-1280215
Hh mutants are degraded by ERAD R-HSA-5362768
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX1 R-HSA-8878171
Axon guidance R-HSA-422475
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
FCERI mediated NF-kB activation R-HSA-2871837
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G1 phase and G1/S transition R-HSA-453279
Interleukin-1 family signaling R-HSA-446652
Signaling by Hedgehog R-HSA-5358351
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
KEAP1-NFE2L2 pathway R-HSA-9755511
Cyclin E associated events during G1/S transition R-HSA-69202
Neddylation R-HSA-8951664
Gene expression (Transcription) R-HSA-74160
Downstream TCR signaling R-HSA-202424
Activation of NF-kappaB in B cells R-HSA-1169091
RNA Polymerase II Transcription R-HSA-73857
ER-Phagosome pathway R-HSA-1236974
Mitotic Anaphase R-HSA-68882
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional regulation by RUNX1 R-HSA-8878171
Stabilization of p53 R-HSA-69541
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog 'off' state R-HSA-5610787
RAF/MAP kinase cascade R-HSA-5673001
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism of amino acids and derivatives R-HSA-71291
Interleukin-1 family signaling R-HSA-446652
Axon guidance R-HSA-422475
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular responses to stimuli R-HSA-8953897
Separation of Sister Chromatids R-HSA-2467813
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic Anaphase R-HSA-68882
Switching of origins to a post-replicative state R-HSA-69052
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic Metaphase and Anaphase R-HSA-2555396
RNA Polymerase II Transcription R-HSA-73857
Degradation of beta-catenin by the destruction complex R-HSA-195253
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RUNX2 expression and activity R-HSA-8939902
Disorders of transmembrane transporters R-HSA-5619115
PTEN Regulation R-HSA-6807070
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by NOTCH R-HSA-157118
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Orc1 removal from chromatin R-HSA-68949
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
Neddylation R-HSA-8951664
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Innate Immune System R-HSA-168249
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'on' state R-HSA-5632684
TCF dependent signaling in response to WNT R-HSA-201681
Cellular response to hypoxia R-HSA-1234174
G1/S Transition R-HSA-69206
Signaling by Hedgehog R-HSA-5358351
Developmental Biology R-HSA-1266738
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCR signaling R-HSA-202403
S Phase R-HSA-69242
Defective CFTR causes cystic fibrosis R-HSA-5678895
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Gene expression (Transcription) R-HSA-74160
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
Activation of NF-kappaB in B cells R-HSA-1169091
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Generic Transcription Pathway R-HSA-212436
Antigen processing-Cross presentation R-HSA-1236975
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH4 R-HSA-9013694
Synthesis of DNA R-HSA-69239
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mitotic cell cycle R-HSA-453276
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
ER-Phagosome pathway R-HSA-1236974
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of polyamines R-HSA-351202
Interleukin-1 signaling R-HSA-9020702
Beta-catenin independent WNT signaling R-HSA-3858494
Assembly of the pre-replicative complex R-HSA-68867
Degradation of DVL R-HSA-4641258
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin E associated events during G1/S transition R-HSA-69202
Transport of small molecules R-HSA-382551
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G2/M Transition R-HSA-69275
Deubiquitination R-HSA-5688426
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of AXIN R-HSA-4641257
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ABC transporter disorders R-HSA-5619084
Adaptive Immune System R-HSA-1280218
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
DNA Replication R-HSA-69306
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PCP/CE pathway R-HSA-4086400
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
HIV Infection R-HSA-162906
UCH proteinases R-HSA-5689603
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI2 by the proteasome R-HSA-5610783
Downstream TCR signaling R-HSA-202424
G1/S DNA Damage Checkpoints R-HSA-69615
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular response to chemical stress R-HSA-9711123
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
Cell Cycle Checkpoints R-HSA-69620
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of RAS by GAPs R-HSA-5658442
Post-translational protein modification R-HSA-597592
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by WNT R-HSA-195721
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Programmed Cell Death R-HSA-5357801
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC-family proteins mediated transport R-HSA-382556
Transcriptional regulation by RUNX3 R-HSA-8878159
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of Apoptosis R-HSA-169911
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
M Phase R-HSA-68886
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ROBO receptors R-HSA-376176
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Apoptosis R-HSA-109581
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
Neddylation R-HSA-8951664
Infectious disease R-HSA-5663205
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog 'off' state R-HSA-5610787
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of RNA R-HSA-8953854
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX2 R-HSA-8878166
Nuclear events mediated by NFE2L2 R-HSA-9759194
Downstream TCR signaling R-HSA-202424
DNA Replication Pre-Initiation R-HSA-69002
Degradation of GLI1 by the proteasome R-HSA-5610780
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Beta-catenin independent WNT signaling R-HSA-3858494
Class I MHC mediated antigen processing & presentation R-HSA-983169
Apoptosis R-HSA-109581
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of amino acids and derivatives R-HSA-71291
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular responses to stimuli R-HSA-8953897
Antigen processing-Cross presentation R-HSA-1236975
Regulation of PTEN stability and activity R-HSA-8948751
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G2/M Checkpoints R-HSA-69481
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
UCH proteinases R-HSA-5689603
Cellular response to hypoxia R-HSA-1234174
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism of polyamines R-HSA-351202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
MAPK6/MAPK4 signaling R-HSA-5687128
Gene expression (Transcription) R-HSA-74160
TCR signaling R-HSA-202403
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular responses to stress R-HSA-2262752
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of AXIN R-HSA-4641257
Degradation of GLI2 by the proteasome R-HSA-5610783
PCP/CE pathway R-HSA-4086400
MAPK1/MAPK3 signaling R-HSA-5684996
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Immune System R-HSA-168256
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH4 R-HSA-9013694
ABC-family proteins mediated transport R-HSA-382556
Degradation of DVL R-HSA-4641258
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular response to chemical stress R-HSA-9711123
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S Transition R-HSA-69206
Regulation of RAS by GAPs R-HSA-5658442
Signaling by WNT R-HSA-195721
Signaling by NOTCH R-HSA-157118
Cell Cycle Checkpoints R-HSA-69620
Separation of Sister Chromatids R-HSA-2467813
Vpu mediated degradation of CD4 R-HSA-180534
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog ligand biogenesis R-HSA-5358346
Signal Transduction R-HSA-162582
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 signaling R-HSA-9020702
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent DNA Damage Response R-HSA-69610
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ABC transporter disorders R-HSA-5619084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic G2-G2/M phases R-HSA-453274
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nervous system development R-HSA-9675108
Hedgehog 'on' state R-HSA-5632684
Signaling by Interleukins R-HSA-449147
C-type lectin receptors (CLRs) R-HSA-5621481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Interleukin-1 family signaling R-HSA-446652
Transport of small molecules R-HSA-382551
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
Regulation of mitotic cell cycle R-HSA-453276
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle, Mitotic R-HSA-69278
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication R-HSA-69306
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disorders of transmembrane transporters R-HSA-5619115
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism R-HSA-1430728
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
PTEN Regulation R-HSA-6807070
HIV Infection R-HSA-162906
Deubiquitination R-HSA-5688426
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G2/M Transition R-HSA-69275
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by Hedgehog R-HSA-5358351
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle R-HSA-1640170
Regulation of RUNX2 expression and activity R-HSA-8939902
Hh mutants are degraded by ERAD R-HSA-5362768
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of beta-catenin by the destruction complex R-HSA-195253
Developmental Biology R-HSA-1266738
Hh mutants abrogate ligand secretion R-HSA-5387390
Host Interactions of HIV factors R-HSA-162909
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Vif-mediated degradation of APOBEC3G R-HSA-180585
MAPK family signaling cascades R-HSA-5683057
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G2/M Transition R-HSA-69275
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Antigen processing-Cross presentation R-HSA-1236975
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transport of small molecules R-HSA-382551
G2/M Checkpoints R-HSA-69481
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PTEN Regulation R-HSA-6807070
Metabolism of polyamines R-HSA-351202
MAPK1/MAPK3 signaling R-HSA-5684996
Infectious disease R-HSA-5663205
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of GLI1 by the proteasome R-HSA-5610780
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of Apoptosis R-HSA-169911
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Stabilization of p53 R-HSA-69541
Neddylation R-HSA-8951664
CLEC7A (Dectin-1) signaling R-HSA-5607764
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ER-Phagosome pathway R-HSA-1236974
Signaling by ROBO receptors R-HSA-376176
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of RNA R-HSA-8953854
Signaling by Interleukins R-HSA-449147
Signaling by NOTCH R-HSA-157118
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of DVL R-HSA-4641258
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to hypoxia R-HSA-1234174
ABC-family proteins mediated transport R-HSA-382556
Programmed Cell Death R-HSA-5357801
PIP3 activates AKT signaling R-HSA-1257604
DNA Replication Pre-Initiation R-HSA-69002
Signaling by Hedgehog R-HSA-5358351
MAPK family signaling cascades R-HSA-5683057
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by WNT R-HSA-195721
Signaling by NOTCH4 R-HSA-9013694
HIV Infection R-HSA-162906
Disorders of transmembrane transporters R-HSA-5619115
Vpu mediated degradation of CD4 R-HSA-180534
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'on' state R-HSA-5632684
Deubiquitination R-HSA-5688426
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G2-G2/M phases R-HSA-453274
Cellular response to chemical stress R-HSA-9711123
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Adaptive Immune System R-HSA-1280218
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX1 R-HSA-8878171
Synthesis of DNA R-HSA-69239
Cellular responses to stimuli R-HSA-8953897
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stress R-HSA-2262752
Metabolism R-HSA-1430728
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of amino acids and derivatives R-HSA-71291
Ub-specific processing proteases R-HSA-5689880
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic G1 phase and G1/S transition R-HSA-453279
Post-translational protein modification R-HSA-597592
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disease R-HSA-1643685
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
Cyclin E associated events during G1/S transition R-HSA-69202
Signal Transduction R-HSA-162582
Interleukin-1 family signaling R-HSA-446652
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RNA Polymerase II Transcription R-HSA-73857
ABC transporter disorders R-HSA-5619084
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S Transition R-HSA-69206
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX2 R-HSA-8878166
Negative regulation of NOTCH4 signaling R-HSA-9604323
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Intracellular signaling by second messengers R-HSA-9006925
Host Interactions of HIV factors R-HSA-162909
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
C-type lectin receptors (CLRs) R-HSA-5621481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of AXIN R-HSA-4641257
Innate Immune System R-HSA-168249
G1/S DNA Damage Checkpoints R-HSA-69615
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Immune System R-HSA-168256
DNA Replication R-HSA-69306
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Hedgehog 'off' state R-HSA-5610787
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of mitotic cell cycle R-HSA-453276
p53-Dependent G1 DNA Damage Response R-HSA-69563
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic Metaphase and Anaphase R-HSA-2555396
Axon guidance R-HSA-422475
Regulation of RAS by GAPs R-HSA-5658442
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 signaling R-HSA-9020702
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
FCERI mediated NF-kB activation R-HSA-2871837
Assembly of the pre-replicative complex R-HSA-68867
RAF/MAP kinase cascade R-HSA-5673001
M Phase R-HSA-68886
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cell Cycle Checkpoints R-HSA-69620
Regulation of PTEN stability and activity R-HSA-8948751
UCH proteinases R-HSA-5689603
Cell Cycle R-HSA-1640170
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disease R-HSA-1643685
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Downstream TCR signaling R-HSA-202424
UCH proteinases R-HSA-5689603
Cell Cycle Checkpoints R-HSA-69620
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by the B Cell Receptor (BCR) R-HSA-983705
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Independent DNA Damage Response R-HSA-69610
Switching of origins to a post-replicative state R-HSA-69052
G2/M Checkpoints R-HSA-69481
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of GLI1 by the proteasome R-HSA-5610780
Host Interactions of HIV factors R-HSA-162909
Assembly of the pre-replicative complex R-HSA-68867
Developmental Biology R-HSA-1266738
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
G1/S Transition R-HSA-69206
Innate Immune System R-HSA-168249
Stabilization of p53 R-HSA-69541
RAF/MAP kinase cascade R-HSA-5673001
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX1 R-HSA-8878171
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Defective CFTR causes cystic fibrosis R-HSA-5678895
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
ER-Phagosome pathway R-HSA-1236974
Degradation of AXIN R-HSA-4641257
Mitotic Anaphase R-HSA-68882
ABC-family proteins mediated transport R-HSA-382556
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
HIV Infection R-HSA-162906
Signaling by Interleukins R-HSA-449147
Separation of Sister Chromatids R-HSA-2467813
Cytokine Signaling in Immune system R-HSA-1280215
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular response to chemical stress R-HSA-9711123
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Immune System R-HSA-168256
Transport of small molecules R-HSA-382551
DNA Replication R-HSA-69306
Intracellular signaling by second messengers R-HSA-9006925
Mitotic G2-G2/M phases R-HSA-453274
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of Apoptosis R-HSA-169911
Degradation of GLI2 by the proteasome R-HSA-5610783
TCF dependent signaling in response to WNT R-HSA-201681
Gene expression (Transcription) R-HSA-74160
G1/S DNA Damage Checkpoints R-HSA-69615
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Neddylation R-HSA-8951664
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Signaling by Hedgehog R-HSA-5358351
Signaling by WNT R-HSA-195721
CLEC7A (Dectin-1) signaling R-HSA-5607764
Deubiquitination R-HSA-5688426
Cyclin E associated events during G1/S transition R-HSA-69202
S Phase R-HSA-69242
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Vif-mediated degradation of APOBEC3G R-HSA-180585
MAPK1/MAPK3 signaling R-HSA-5684996
Ub-specific processing proteases R-HSA-5689880
Hh mutants are degraded by ERAD R-HSA-5362768
Cell Cycle R-HSA-1640170
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Post-translational protein modification R-HSA-597592
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Class I MHC mediated antigen processing & presentation R-HSA-983169
PCP/CE pathway R-HSA-4086400
Orc1 removal from chromatin R-HSA-68949
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
ABC transporter disorders R-HSA-5619084
Metabolism of proteins R-HSA-392499
M Phase R-HSA-68886
PTEN Regulation R-HSA-6807070
Interleukin-1 signaling R-HSA-9020702
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular responses to stimuli R-HSA-8953897
Regulation of PTEN stability and activity R-HSA-8948751
C-type lectin receptors (CLRs) R-HSA-5621481
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activation of NF-kappaB in B cells R-HSA-1169091
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of polyamines R-HSA-351202
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RNA Polymerase II Transcription R-HSA-73857
Hedgehog 'off' state R-HSA-5610787
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Signaling by ROBO receptors R-HSA-376176
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH4 R-HSA-9013694
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle, Mitotic R-HSA-69278
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative regulation of NOTCH4 signaling R-HSA-9604323
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX3 R-HSA-8878159
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
Programmed Cell Death R-HSA-5357801
Disorders of transmembrane transporters R-HSA-5619115
Synthesis of DNA R-HSA-69239
G2/M Transition R-HSA-69275
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of DVL R-HSA-4641258
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism R-HSA-1430728
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Disorders of transmembrane transporters R-HSA-5619115
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism R-HSA-1430728
TCF dependent signaling in response to WNT R-HSA-201681
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular response to hypoxia R-HSA-1234174
PTEN Regulation R-HSA-6807070
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX2 R-HSA-8878166
Innate Immune System R-HSA-168249
Downstream TCR signaling R-HSA-202424
Antigen processing-Cross presentation R-HSA-1236975
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic G2-G2/M phases R-HSA-453274
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of DVL R-HSA-4641258
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
ABC-family proteins mediated transport R-HSA-382556
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Immune System R-HSA-168256
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
Regulation of Apoptosis R-HSA-169911
Signaling by NOTCH4 R-HSA-9013694
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication Pre-Initiation R-HSA-69002
Programmed Cell Death R-HSA-5357801
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
DNA Replication R-HSA-69306
Vpu mediated degradation of CD4 R-HSA-180534
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
G2/M Transition R-HSA-69275
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RAS by GAPs R-HSA-5658442
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Developmental Biology R-HSA-1266738
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Defective CFTR causes cystic fibrosis R-HSA-5678895
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'off' state R-HSA-5610787
Vif-mediated degradation of APOBEC3G R-HSA-180585
Asymmetric localization of PCP proteins R-HSA-4608870
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI2 by the proteasome R-HSA-5610783
Neddylation R-HSA-8951664
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
UCH proteinases R-HSA-5689603
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
KEAP1-NFE2L2 pathway R-HSA-9755511
Stabilization of p53 R-HSA-69541
Signal Transduction R-HSA-162582
Metabolism of polyamines R-HSA-351202
TCR signaling R-HSA-202403
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stimuli R-HSA-8953897
Assembly of the pre-replicative complex R-HSA-68867
Orc1 removal from chromatin R-HSA-68949
Disease R-HSA-1643685
Interleukin-1 signaling R-HSA-9020702
RNA Polymerase II Transcription R-HSA-73857
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants abrogate ligand secretion R-HSA-5387390
FCERI mediated NF-kB activation R-HSA-2871837
Activation of NF-kappaB in B cells R-HSA-1169091
HIV Infection R-HSA-162906
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Hedgehog R-HSA-5358351
Signaling by Interleukins R-HSA-449147
Post-translational protein modification R-HSA-597592
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
p53-Independent DNA Damage Response R-HSA-69610
Ub-specific processing proteases R-HSA-5689880
Synthesis of DNA R-HSA-69239
Mitotic Anaphase R-HSA-68882
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
MAPK family signaling cascades R-HSA-5683057
S Phase R-HSA-69242
Switching of origins to a post-replicative state R-HSA-69052
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transport of small molecules R-HSA-382551
Signaling by NOTCH R-HSA-157118
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Infectious disease R-HSA-5663205
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic G1 phase and G1/S transition R-HSA-453279
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog 'on' state R-HSA-5632684
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle Checkpoints R-HSA-69620
MAPK6/MAPK4 signaling R-HSA-5687128
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stress R-HSA-2262752
ER-Phagosome pathway R-HSA-1236974
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Dependent G1 DNA Damage Response R-HSA-69563
Deubiquitination R-HSA-5688426
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
Cell Cycle R-HSA-1640170
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of amino acids and derivatives R-HSA-71291
Separation of Sister Chromatids R-HSA-2467813
Class I MHC mediated antigen processing & presentation R-HSA-983169
Assembly of the pre-replicative complex R-HSA-68867
UCH proteinases R-HSA-5689603
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic G2-G2/M phases R-HSA-453274
PTEN Regulation R-HSA-6807070
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stimuli R-HSA-8953897
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Programmed Cell Death R-HSA-5357801
Neddylation R-HSA-8951664
Mitotic G1 phase and G1/S transition R-HSA-453279
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants abrogate ligand secretion R-HSA-5387390
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication Pre-Initiation R-HSA-69002
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PCP/CE pathway R-HSA-4086400
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of DVL R-HSA-4641258
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Intracellular signaling by second messengers R-HSA-9006925
Axon guidance R-HSA-422475
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism R-HSA-1430728
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-1 family signaling R-HSA-446652
Apoptosis R-HSA-109581
Signaling by WNT R-HSA-195721
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
Innate Immune System R-HSA-168249
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Checkpoints R-HSA-69481
Metabolism of amino acids and derivatives R-HSA-71291
DNA Replication R-HSA-69306
Mitotic Metaphase and Anaphase R-HSA-2555396
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
Transcriptional regulation by RUNX2 R-HSA-8878166
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Interleukin-1 signaling R-HSA-9020702
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of proteins R-HSA-392499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G1/S Transition R-HSA-69206
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog ligand biogenesis R-HSA-5358346
FCERI mediated NF-kB activation R-HSA-2871837
HIV Infection R-HSA-162906
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Separation of Sister Chromatids R-HSA-2467813
Post-translational protein modification R-HSA-597592
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
RAF/MAP kinase cascade R-HSA-5673001
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Orc1 removal from chromatin R-HSA-68949
Adaptive Immune System R-HSA-1280218
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to hypoxia R-HSA-1234174
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transcriptional regulation by RUNX3 R-HSA-8878159
Immune System R-HSA-168256
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nuclear events mediated by NFE2L2 R-HSA-9759194
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of Apoptosis R-HSA-169911
Signaling by Hedgehog R-HSA-5358351
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Synthesis of DNA R-HSA-69239
Degradation of AXIN R-HSA-4641257
Vpu mediated degradation of CD4 R-HSA-180534
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
S Phase R-HSA-69242
M Phase R-HSA-68886
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Anaphase R-HSA-68882
Regulation of RUNX3 expression and activity R-HSA-8941858
Disorders of transmembrane transporters R-HSA-5619115
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
CLEC7A (Dectin-1) signaling R-HSA-5607764
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle R-HSA-1640170
Downstream TCR signaling R-HSA-202424
Hh mutants are degraded by ERAD R-HSA-5362768
Cell Cycle, Mitotic R-HSA-69278
Switching of origins to a post-replicative state R-HSA-69052
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of GLI2 by the proteasome R-HSA-5610783
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
MAPK6/MAPK4 signaling R-HSA-5687128
C-type lectin receptors (CLRs) R-HSA-5621481
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
Deubiquitination R-HSA-5688426
Defective CFTR causes cystic fibrosis R-HSA-5678895
TCR signaling R-HSA-202403
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular response to chemical stress R-HSA-9711123
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ABC-family proteins mediated transport R-HSA-382556
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH4 R-HSA-9013694
Negative regulation of NOTCH4 signaling R-HSA-9604323
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK1/MAPK3 signaling R-HSA-5684996
KEAP1-NFE2L2 pathway R-HSA-9755511
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Ub-specific processing proteases R-HSA-5689880
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ABC transporter disorders R-HSA-5619084
G1/S DNA Damage Checkpoints R-HSA-69615
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signal Transduction R-HSA-162582
Metabolism of polyamines R-HSA-351202
p53-Independent DNA Damage Response R-HSA-69610
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Developmental Biology R-HSA-1266738
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX2 R-HSA-8878166
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PTEN Regulation R-HSA-6807070
Regulation of RUNX2 expression and activity R-HSA-8939902
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Metabolism R-HSA-1430728
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cellular responses to stress R-HSA-2262752
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interleukin-1 signaling R-HSA-9020702
Infectious disease R-HSA-5663205
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signal Transduction R-HSA-162582
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
ABC-family proteins mediated transport R-HSA-382556
Separation of Sister Chromatids R-HSA-2467813
Regulation of Apoptosis R-HSA-169911
Generic Transcription Pathway R-HSA-212436
Cell Cycle, Mitotic R-HSA-69278
MAPK6/MAPK4 signaling R-HSA-5687128
UCH proteinases R-HSA-5689603
p53-Independent DNA Damage Response R-HSA-69610
Activation of NF-kappaB in B cells R-HSA-1169091
Neddylation R-HSA-8951664
Metabolism of amino acids and derivatives R-HSA-71291
G1/S Transition R-HSA-69206
Signaling by the B Cell Receptor (BCR) R-HSA-983705
S Phase R-HSA-69242
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of proteins R-HSA-392499
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Stabilization of p53 R-HSA-69541
Signaling by Interleukins R-HSA-449147
G1/S DNA Damage Checkpoints R-HSA-69615
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Innate Immune System R-HSA-168249
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
DNA Replication Pre-Initiation R-HSA-69002
FCERI mediated NF-kB activation R-HSA-2871837
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic G2-G2/M phases R-HSA-453274
Defective CFTR causes cystic fibrosis R-HSA-5678895
M Phase R-HSA-68886
HIV Infection R-HSA-162906
Apoptosis R-HSA-109581
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX3 R-HSA-8878159
ABC transporter disorders R-HSA-5619084
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog ligand biogenesis R-HSA-5358346
Adaptive Immune System R-HSA-1280218
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by Hedgehog R-HSA-5358351
Orc1 removal from chromatin R-HSA-68949
ER-Phagosome pathway R-HSA-1236974
RNA Polymerase II Transcription R-HSA-73857
Degradation of AXIN R-HSA-4641257
Assembly of the pre-replicative complex R-HSA-68867
Cellular response to hypoxia R-HSA-1234174
Switching of origins to a post-replicative state R-HSA-69052
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of beta-catenin by the destruction complex R-HSA-195253
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Interleukin-1 family signaling R-HSA-446652
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic Anaphase R-HSA-68882
Cellular responses to stimuli R-HSA-8953897
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Intracellular signaling by second messengers R-HSA-9006925
Cellular response to chemical stress R-HSA-9711123
Cyclin E associated events during G1/S transition R-HSA-69202
Vpu mediated degradation of CD4 R-HSA-180534
Host Interactions of HIV factors R-HSA-162909
Hh mutants abrogate ligand secretion R-HSA-5387390
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of mitotic cell cycle R-HSA-453276
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RAF/MAP kinase cascade R-HSA-5673001
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
TCR signaling R-HSA-202403
Post-translational protein modification R-HSA-597592
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RAS by GAPs R-HSA-5658442
Ub-specific processing proteases R-HSA-5689880
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
G2/M Checkpoints R-HSA-69481
Signaling by NOTCH R-HSA-157118
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Negative regulation of NOTCH4 signaling R-HSA-9604323
C-type lectin receptors (CLRs) R-HSA-5621481
Downstream TCR signaling R-HSA-202424
Gene expression (Transcription) R-HSA-74160
Hedgehog 'on' state R-HSA-5632684
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by WNT R-HSA-195721
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Axon guidance R-HSA-422475
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transport of small molecules R-HSA-382551
Degradation of GLI1 by the proteasome R-HSA-5610780
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle R-HSA-1640170
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants are degraded by ERAD R-HSA-5362768
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by ROBO receptors R-HSA-376176
PCP/CE pathway R-HSA-4086400
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX3 expression and activity R-HSA-8941858
MAPK family signaling cascades R-HSA-5683057
DNA Replication R-HSA-69306
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX1 R-HSA-8878171
Asymmetric localization of PCP proteins R-HSA-4608870
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of RNA R-HSA-8953854
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of DVL R-HSA-4641258
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Vpu mediated degradation of CD4 R-HSA-180534
Signal Transduction R-HSA-162582
Metabolism of amino acids and derivatives R-HSA-71291
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of mitotic cell cycle R-HSA-453276
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of AXIN R-HSA-4641257
Ub-specific processing proteases R-HSA-5689880
Nervous system development R-HSA-9675108
Metabolism R-HSA-1430728
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Asymmetric localization of PCP proteins R-HSA-4608870
Immune System R-HSA-168256
PIP3 activates AKT signaling R-HSA-1257604
Degradation of DVL R-HSA-4641258
Cell Cycle R-HSA-1640170
MAPK family signaling cascades R-HSA-5683057
G2/M Transition R-HSA-69275
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Negative regulation of NOTCH4 signaling R-HSA-9604323
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PCP/CE pathway R-HSA-4086400
Cellular response to hypoxia R-HSA-1234174
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Cell Cycle Checkpoints R-HSA-69620
Degradation of GLI2 by the proteasome R-HSA-5610783
Mitotic Metaphase and Anaphase R-HSA-2555396
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of RNA R-HSA-8953854
ABC-family proteins mediated transport R-HSA-382556
Axon guidance R-HSA-422475
Host Interactions of HIV factors R-HSA-162909
Deubiquitination R-HSA-5688426
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
p53-Dependent G1 DNA Damage Response R-HSA-69563
FCERI mediated NF-kB activation R-HSA-2871837
Synthesis of DNA R-HSA-69239
Adaptive Immune System R-HSA-1280218
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 signaling R-HSA-9020702
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by ROBO receptors R-HSA-376176
Signaling by NOTCH4 R-HSA-9013694
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stress R-HSA-2262752
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
M Phase R-HSA-68886
Stabilization of p53 R-HSA-69541
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing-Cross presentation R-HSA-1236975
Signaling by Interleukins R-HSA-449147
G1/S Transition R-HSA-69206
Apoptosis R-HSA-109581
Mitotic Anaphase R-HSA-68882
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of polyamines R-HSA-351202
TCF dependent signaling in response to WNT R-HSA-201681
Assembly of the pre-replicative complex R-HSA-68867
Developmental Biology R-HSA-1266738
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX3 R-HSA-8878159
Downstream TCR signaling R-HSA-202424
ER-Phagosome pathway R-HSA-1236974
MAPK1/MAPK3 signaling R-HSA-5684996
Infectious disease R-HSA-5663205
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G2-G2/M phases R-HSA-453274
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog 'on' state R-HSA-5632684
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular response to chemical stress R-HSA-9711123
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
Disease R-HSA-1643685
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Innate Immune System R-HSA-168249
Separation of Sister Chromatids R-HSA-2467813
RNA Polymerase II Transcription R-HSA-73857
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by WNT R-HSA-195721
NIK-->noncanonical NF-kB signaling R-HSA-5676590
G2/M Checkpoints R-HSA-69481
Transport of small molecules R-HSA-382551
Hedgehog 'off' state R-HSA-5610787
DNA Replication R-HSA-69306
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of Apoptosis R-HSA-169911
PTEN Regulation R-HSA-6807070
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vif-mediated degradation of APOBEC3G R-HSA-180585
Post-translational protein modification R-HSA-597592
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
S Phase R-HSA-69242
Orc1 removal from chromatin R-HSA-68949
p53-Independent DNA Damage Response R-HSA-69610
Regulation of PTEN stability and activity R-HSA-8948751
DNA Replication Pre-Initiation R-HSA-69002
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of RAS by GAPs R-HSA-5658442
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hh mutants are degraded by ERAD R-HSA-5362768
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog ligand biogenesis R-HSA-5358346
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disorders of transmembrane transporters R-HSA-5619115
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Nuclear events mediated by NFE2L2 R-HSA-9759194
DNA Replication R-HSA-69306
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PTEN Regulation R-HSA-6807070
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of RNA R-HSA-8953854
MAPK family signaling cascades R-HSA-5683057
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
FCERI mediated NF-kB activation R-HSA-2871837
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by ROBO receptors R-HSA-376176
Hedgehog ligand biogenesis R-HSA-5358346
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cell Cycle, Mitotic R-HSA-69278
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by NOTCH R-HSA-157118
UCH proteinases R-HSA-5689603
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of polyamines R-HSA-351202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RAF/MAP kinase cascade R-HSA-5673001
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX2 R-HSA-8878166
Stabilization of p53 R-HSA-69541
G2/M Checkpoints R-HSA-69481
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by WNT R-HSA-195721
Intracellular signaling by second messengers R-HSA-9006925
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Developmental Biology R-HSA-1266738
G2/M Transition R-HSA-69275
Interleukin-1 family signaling R-HSA-446652
TCR signaling R-HSA-202403
Programmed Cell Death R-HSA-5357801
Separation of Sister Chromatids R-HSA-2467813
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of RAS by GAPs R-HSA-5658442
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK6/MAPK4 signaling R-HSA-5687128
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of GLI2 by the proteasome R-HSA-5610783
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX3 expression and activity R-HSA-8941858
MAPK1/MAPK3 signaling R-HSA-5684996
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by Hedgehog R-HSA-5358351
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
Infectious disease R-HSA-5663205
Cell Cycle Checkpoints R-HSA-69620
ABC-family proteins mediated transport R-HSA-382556
Nervous system development R-HSA-9675108
Hedgehog 'off' state R-HSA-5610787
Signal Transduction R-HSA-162582
Degradation of AXIN R-HSA-4641257
Mitotic G1 phase and G1/S transition R-HSA-453279
Axon guidance R-HSA-422475
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Immune System R-HSA-168256
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Adaptive Immune System R-HSA-1280218
Cellular responses to stress R-HSA-2262752
M Phase R-HSA-68886
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'on' state R-HSA-5632684
Cellular response to hypoxia R-HSA-1234174
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of DVL R-HSA-4641258
Negative regulation of NOTCH4 signaling R-HSA-9604323
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Deubiquitination R-HSA-5688426
Cellular responses to stimuli R-HSA-8953897
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX1 R-HSA-8878171
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX3 R-HSA-8878159
Asymmetric localization of PCP proteins R-HSA-4608870
Apoptosis R-HSA-109581
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular response to chemical stress R-HSA-9711123
Metabolism of proteins R-HSA-392499
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
PCP/CE pathway R-HSA-4086400
Innate Immune System R-HSA-168249
Assembly of the pre-replicative complex R-HSA-68867
Neddylation R-HSA-8951664
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH4 R-HSA-9013694
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 signaling R-HSA-9020702
Regulation of PTEN stability and activity R-HSA-8948751
DNA Replication Pre-Initiation R-HSA-69002
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ER-Phagosome pathway R-HSA-1236974
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by Interleukins R-HSA-449147
Class I MHC mediated antigen processing & presentation R-HSA-983169
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S Transition R-HSA-69206
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Downstream TCR signaling R-HSA-202424
Transport of small molecules R-HSA-382551
Switching of origins to a post-replicative state R-HSA-69052
Mitotic G2-G2/M phases R-HSA-453274
C-type lectin receptors (CLRs) R-HSA-5621481
Synthesis of DNA R-HSA-69239
Regulation of mitotic cell cycle R-HSA-453276
Gene expression (Transcription) R-HSA-74160
Disorders of transmembrane transporters R-HSA-5619115
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of GLI1 by the proteasome R-HSA-5610780
PIP3 activates AKT signaling R-HSA-1257604
Post-translational protein modification R-HSA-597592
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
Metabolism R-HSA-1430728
Axon guidance R-HSA-422475
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
HIV Infection R-HSA-162906
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of DVL R-HSA-4641258
Host Interactions of HIV factors R-HSA-162909
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Hedgehog R-HSA-5358351
Signaling by Interleukins R-HSA-449147
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
RAF/MAP kinase cascade R-HSA-5673001
Nuclear events mediated by NFE2L2 R-HSA-9759194
ABC-family proteins mediated transport R-HSA-382556
Innate Immune System R-HSA-168249
DNA Replication Pre-Initiation R-HSA-69002
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Regulation of RAS by GAPs R-HSA-5658442
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by ROBO receptors R-HSA-376176
Class I MHC mediated antigen processing & presentation R-HSA-983169
PCP/CE pathway R-HSA-4086400
p53-Dependent G1 DNA Damage Response R-HSA-69563
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of AXIN R-HSA-4641257
DNA Replication R-HSA-69306
Negative regulation of NOTCH4 signaling R-HSA-9604323
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic G2-G2/M phases R-HSA-453274
FCERI mediated NF-kB activation R-HSA-2871837
Synthesis of DNA R-HSA-69239
Signal Transduction R-HSA-162582
Infectious disease R-HSA-5663205
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Disease R-HSA-1643685
Regulation of RUNX3 expression and activity R-HSA-8941858
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Cellular responses to stimuli R-HSA-8953897
Degradation of beta-catenin by the destruction complex R-HSA-195253
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
Transcriptional regulation by RUNX3 R-HSA-8878159
Deubiquitination R-HSA-5688426
Cyclin E associated events during G1/S transition R-HSA-69202
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 signaling R-HSA-9020702
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Nervous system development R-HSA-9675108
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle, Mitotic R-HSA-69278
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by NOTCH4 R-HSA-9013694
Hh mutants are degraded by ERAD R-HSA-5362768
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Separation of Sister Chromatids R-HSA-2467813
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC transporter disorders R-HSA-5619084
Neddylation R-HSA-8951664
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream TCR signaling R-HSA-202424
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog 'on' state R-HSA-5632684
Developmental Biology R-HSA-1266738
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants abrogate ligand secretion R-HSA-5387390
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of mitotic cell cycle R-HSA-453276
Beta-catenin independent WNT signaling R-HSA-3858494
G1/S Transition R-HSA-69206
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 family signaling R-HSA-446652
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
M Phase R-HSA-68886
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by WNT R-HSA-195721
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
Cytokine Signaling in Immune system R-HSA-1280215
Vpu mediated degradation of CD4 R-HSA-180534
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Immune System R-HSA-168256
Mitotic G1 phase and G1/S transition R-HSA-453279
TCF dependent signaling in response to WNT R-HSA-201681
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Independent DNA Damage Response R-HSA-69610
Signaling by NOTCH R-HSA-157118
G2/M Transition R-HSA-69275
MAPK family signaling cascades R-HSA-5683057
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of polyamines R-HSA-351202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of PTEN stability and activity R-HSA-8948751
Switching of origins to a post-replicative state R-HSA-69052
Intracellular signaling by second messengers R-HSA-9006925
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stress R-HSA-2262752
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX1 R-HSA-8878171
PTEN Regulation R-HSA-6807070
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of amino acids and derivatives R-HSA-71291
Orc1 removal from chromatin R-HSA-68949
Adaptive Immune System R-HSA-1280218
Transport of small molecules R-HSA-382551
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of Apoptosis R-HSA-169911
S Phase R-HSA-69242
G2/M Checkpoints R-HSA-69481
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to chemical stress R-HSA-9711123
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX2 R-HSA-8878166
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to hypoxia R-HSA-1234174
ER-Phagosome pathway R-HSA-1236974
Mitotic Anaphase R-HSA-68882
Apoptosis R-HSA-109581
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle Checkpoints R-HSA-69620

Expression Atlas ENSG00000013275
NCBI gene (formerly Entrezgene) 5704
GeneCards 9551
HGNC Symbol HGNC:9551
MIM gene 602707
UniProtKB Gene Name P43686
WikiGene 5704
Gene: PSMB3
Ensembl ID : ENSG00000277791
Description: proteasome 20S subunit beta 3
Gene Synonyms: HC10-II,MGC4147
6 APIs:
240 Possible Orthologues:

Metabolism R-HSA-1430728
Disorders of transmembrane transporters R-HSA-5619115
S Phase R-HSA-69242
Metabolism of proteins R-HSA-392499
Orc1 removal from chromatin R-HSA-68949
Mitotic Anaphase R-HSA-68882
Hh mutants are degraded by ERAD R-HSA-5362768
Disease R-HSA-1643685
Programmed Cell Death R-HSA-5357801
Cyclin E associated events during G1/S transition R-HSA-69202
G1/S DNA Damage Checkpoints R-HSA-69615
Hedgehog 'off' state R-HSA-5610787
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of polyamines R-HSA-351202
ER-Phagosome pathway R-HSA-1236974
Cell Cycle Checkpoints R-HSA-69620
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 family signaling R-HSA-446652
Signaling by Interleukins R-HSA-449147
Gene expression (Transcription) R-HSA-74160
Apoptosis R-HSA-109581
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by Hedgehog R-HSA-5358351
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of Apoptosis R-HSA-169911
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle, Mitotic R-HSA-69278
Transport of small molecules R-HSA-382551
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G2-G2/M phases R-HSA-453274
Downstream TCR signaling R-HSA-202424
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of amino acids and derivatives R-HSA-71291
PTEN Regulation R-HSA-6807070
Defective CFTR causes cystic fibrosis R-HSA-5678895
PIP3 activates AKT signaling R-HSA-1257604
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
M Phase R-HSA-68886
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S Transition R-HSA-69206
Cellular responses to stress R-HSA-2262752
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hh mutants abrogate ligand secretion R-HSA-5387390
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by WNT R-HSA-195721
Interleukin-1 signaling R-HSA-9020702
RNA Polymerase II Transcription R-HSA-73857
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of RNA R-HSA-8953854
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular response to chemical stress R-HSA-9711123
Signaling by ROBO receptors R-HSA-376176
Nervous system development R-HSA-9675108
Stabilization of p53 R-HSA-69541
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of mitotic cell cycle R-HSA-453276
Regulation of RAS by GAPs R-HSA-5658442
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Beta-catenin independent WNT signaling R-HSA-3858494
C-type lectin receptors (CLRs) R-HSA-5621481
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional regulation by RUNX3 R-HSA-8878159
MAPK family signaling cascades R-HSA-5683057
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Negative regulation of NOTCH4 signaling R-HSA-9604323
TCR signaling R-HSA-202403
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
Hedgehog ligand biogenesis R-HSA-5358346
Switching of origins to a post-replicative state R-HSA-69052
Assembly of the pre-replicative complex R-HSA-68867
Regulation of RUNX2 expression and activity R-HSA-8939902
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular response to hypoxia R-HSA-1234174
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of DVL R-HSA-4641258
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic Metaphase and Anaphase R-HSA-2555396
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of beta-catenin by the destruction complex R-HSA-195253
Synthesis of DNA R-HSA-69239
Cell Cycle R-HSA-1640170
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Post-translational protein modification R-HSA-597592
TCF dependent signaling in response to WNT R-HSA-201681
Intracellular signaling by second messengers R-HSA-9006925
Separation of Sister Chromatids R-HSA-2467813
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PCP/CE pathway R-HSA-4086400
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
DNA Replication R-HSA-69306
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
ABC transporter disorders R-HSA-5619084
KEAP1-NFE2L2 pathway R-HSA-9755511
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of AXIN R-HSA-4641257
UCH proteinases R-HSA-5689603
Host Interactions of HIV factors R-HSA-162909
ABC-family proteins mediated transport R-HSA-382556
Degradation of GLI1 by the proteasome R-HSA-5610780
Antigen processing-Cross presentation R-HSA-1236975
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Developmental Biology R-HSA-1266738
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of GLI2 by the proteasome R-HSA-5610783
G2/M Checkpoints R-HSA-69481
Neddylation R-HSA-8951664
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
DNA Replication Pre-Initiation R-HSA-69002
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RAF/MAP kinase cascade R-HSA-5673001
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by NOTCH R-HSA-157118
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hedgehog 'on' state R-HSA-5632684
Signaling by NOTCH4 R-HSA-9013694
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Independent DNA Damage Response R-HSA-69610
Assembly of the pre-replicative complex R-HSA-68867
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of DVL R-HSA-4641258
PCP/CE pathway R-HSA-4086400
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of polyamines R-HSA-351202
Vpu mediated degradation of CD4 R-HSA-180534
Deubiquitination R-HSA-5688426
Hedgehog 'off' state R-HSA-5610787
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Stabilization of p53 R-HSA-69541
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Metaphase and Anaphase R-HSA-2555396
Beta-catenin independent WNT signaling R-HSA-3858494
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
ABC-family proteins mediated transport R-HSA-382556
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
Negative regulation of NOTCH4 signaling R-HSA-9604323
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI2 by the proteasome R-HSA-5610783
Developmental Biology R-HSA-1266738
G1/S Transition R-HSA-69206
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Adaptive Immune System R-HSA-1280218
Mitotic G2-G2/M phases R-HSA-453274
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signal Transduction R-HSA-162582
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Post-translational protein modification R-HSA-597592
DNA Replication R-HSA-69306
Transcriptional regulation by RUNX3 R-HSA-8878159
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by ROBO receptors R-HSA-376176
Disorders of transmembrane transporters R-HSA-5619115
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream TCR signaling R-HSA-202424
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Antigen processing-Cross presentation R-HSA-1236975
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
PTEN Regulation R-HSA-6807070
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular responses to stimuli R-HSA-8953897
Signaling by WNT R-HSA-195721
Orc1 removal from chromatin R-HSA-68949
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cell Cycle Checkpoints R-HSA-69620
S Phase R-HSA-69242
TCR signaling R-HSA-202403
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
UCH proteinases R-HSA-5689603
Switching of origins to a post-replicative state R-HSA-69052
Ub-specific processing proteases R-HSA-5689880
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to hypoxia R-HSA-1234174
Interleukin-1 family signaling R-HSA-446652
Neddylation R-HSA-8951664
Regulation of mitotic cell cycle R-HSA-453276
Gene expression (Transcription) R-HSA-74160
Cell Cycle, Mitotic R-HSA-69278
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
HIV Infection R-HSA-162906
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
Axon guidance R-HSA-422475
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
MAPK family signaling cascades R-HSA-5683057
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
FCERI mediated NF-kB activation R-HSA-2871837
Apoptosis R-HSA-109581
Mitotic Anaphase R-HSA-68882
Degradation of GLI1 by the proteasome R-HSA-5610780
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX2 R-HSA-8878166
TCF dependent signaling in response to WNT R-HSA-201681
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of RNA R-HSA-8953854
Synthesis of DNA R-HSA-69239
Signaling by NOTCH R-HSA-157118
RAF/MAP kinase cascade R-HSA-5673001
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Hedgehog 'on' state R-HSA-5632684
Nervous system development R-HSA-9675108
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH4 R-HSA-9013694
KEAP1-NFE2L2 pathway R-HSA-9755511
PIP3 activates AKT signaling R-HSA-1257604
Programmed Cell Death R-HSA-5357801
Regulation of RAS by GAPs R-HSA-5658442
DNA Replication Pre-Initiation R-HSA-69002
Generic Transcription Pathway R-HSA-212436
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MAPK6/MAPK4 signaling R-HSA-5687128
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ER-Phagosome pathway R-HSA-1236974
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transport of small molecules R-HSA-382551
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RNA Polymerase II Transcription R-HSA-73857
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Defective CFTR causes cystic fibrosis R-HSA-5678895
G2/M Checkpoints R-HSA-69481
Degradation of AXIN R-HSA-4641257
Interleukin-1 signaling R-HSA-9020702
Host Interactions of HIV factors R-HSA-162909
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of RUNX2 expression and activity R-HSA-8939902
Immune System R-HSA-168256
Disease R-HSA-1643685
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Class I MHC mediated antigen processing & presentation R-HSA-983169
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of proteins R-HSA-392499
Signaling by Interleukins R-HSA-449147
Hh mutants abrogate ligand secretion R-HSA-5387390
ABC transporter disorders R-HSA-5619084
Hedgehog 'off' state R-HSA-5610787
Generic Transcription Pathway R-HSA-212436
Disorders of transmembrane transporters R-HSA-5619115
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX2 R-HSA-8878166
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Deubiquitination R-HSA-5688426
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of GLI2 by the proteasome R-HSA-5610783
Separation of Sister Chromatids R-HSA-2467813
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of RUNX2 expression and activity R-HSA-8939902
Class I MHC mediated antigen processing & presentation R-HSA-983169
RAF/MAP kinase cascade R-HSA-5673001
Hedgehog 'on' state R-HSA-5632684
ABC-family proteins mediated transport R-HSA-382556
Host Interactions of HIV factors R-HSA-162909
Mitotic Metaphase and Anaphase R-HSA-2555396
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI1 by the proteasome R-HSA-5610780
Assembly of the pre-replicative complex R-HSA-68867
HIV Infection R-HSA-162906
Intracellular signaling by second messengers R-HSA-9006925
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH R-HSA-157118
Interleukin-1 family signaling R-HSA-446652
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of DVL R-HSA-4641258
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
C-type lectin receptors (CLRs) R-HSA-5621481
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transport of small molecules R-HSA-382551
Metabolism of polyamines R-HSA-351202
Signaling by Hedgehog R-HSA-5358351
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of beta-catenin by the destruction complex R-HSA-195253
MAPK family signaling cascades R-HSA-5683057
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hh mutants are degraded by ERAD R-HSA-5362768
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PIP3 activates AKT signaling R-HSA-1257604
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Axon guidance R-HSA-422475
Vif-mediated degradation of APOBEC3G R-HSA-180585
DNA Replication R-HSA-69306
Regulation of mitotic cell cycle R-HSA-453276
Gene expression (Transcription) R-HSA-74160
PCP/CE pathway R-HSA-4086400
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic G1 phase and G1/S transition R-HSA-453279
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transcriptional regulation by RUNX1 R-HSA-8878171
UCH proteinases R-HSA-5689603
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
PTEN Regulation R-HSA-6807070
ABC transporter disorders R-HSA-5619084
Cell Cycle Checkpoints R-HSA-69620
Synthesis of DNA R-HSA-69239
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
M Phase R-HSA-68886
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Adaptive Immune System R-HSA-1280218
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to hypoxia R-HSA-1234174
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic Anaphase R-HSA-68882
Metabolism of proteins R-HSA-392499
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stress R-HSA-2262752
Downstream TCR signaling R-HSA-202424
Interleukin-1 signaling R-HSA-9020702
Signaling by WNT R-HSA-195721
Programmed Cell Death R-HSA-5357801
Antigen processing-Cross presentation R-HSA-1236975
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of RNA R-HSA-8953854
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog ligand biogenesis R-HSA-5358346
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Stabilization of p53 R-HSA-69541
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ER-Phagosome pathway R-HSA-1236974
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants abrogate ligand secretion R-HSA-5387390
TCR signaling R-HSA-202403
Immune System R-HSA-168256
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent DNA Damage Response R-HSA-69610
Vpu mediated degradation of CD4 R-HSA-180534
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G2/M Checkpoints R-HSA-69481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S Transition R-HSA-69206
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Disease R-HSA-1643685
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of Apoptosis R-HSA-169911
Orc1 removal from chromatin R-HSA-68949
Cytokine Signaling in Immune system R-HSA-1280215
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular response to chemical stress R-HSA-9711123
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by ROBO receptors R-HSA-376176
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of AXIN R-HSA-4641257
Metabolism R-HSA-1430728
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
Signal Transduction R-HSA-162582
Neddylation R-HSA-8951664
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH R-HSA-157118
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by Interleukins R-HSA-449147
Transport of small molecules R-HSA-382551
Developmental Biology R-HSA-1266738
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of AXIN R-HSA-4641257
UCH proteinases R-HSA-5689603
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing-Cross presentation R-HSA-1236975
Deubiquitination R-HSA-5688426
G2/M Transition R-HSA-69275
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of Apoptosis R-HSA-169911
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Axon guidance R-HSA-422475
Post-translational protein modification R-HSA-597592
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK6/MAPK4 signaling R-HSA-5687128
Transcriptional regulation by RUNX1 R-HSA-8878171
ER-Phagosome pathway R-HSA-1236974
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of RAS by GAPs R-HSA-5658442
HIV Infection R-HSA-162906
Cellular response to hypoxia R-HSA-1234174
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by ROBO receptors R-HSA-376176
Synthesis of DNA R-HSA-69239
Gene expression (Transcription) R-HSA-74160
RAF/MAP kinase cascade R-HSA-5673001
Hedgehog ligand biogenesis R-HSA-5358346
Downstream TCR signaling R-HSA-202424
Infectious disease R-HSA-5663205
S Phase R-HSA-69242
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX3 R-HSA-8878159
Separation of Sister Chromatids R-HSA-2467813
FCERI mediated NF-kB activation R-HSA-2871837
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog 'on' state R-HSA-5632684
Class I MHC mediated antigen processing & presentation R-HSA-983169
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic G1 phase and G1/S transition R-HSA-453279
PIP3 activates AKT signaling R-HSA-1257604
Degradation of DVL R-HSA-4641258
MAPK family signaling cascades R-HSA-5683057
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
Cyclin E associated events during G1/S transition R-HSA-69202
Apoptosis R-HSA-109581
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
TCR signaling R-HSA-202403
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by WNT R-HSA-195721
p53-Independent DNA Damage Response R-HSA-69610
Metabolism R-HSA-1430728
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Programmed Cell Death R-HSA-5357801
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Activation of NF-kappaB in B cells R-HSA-1169091
ABC transporter disorders R-HSA-5619084
ABC-family proteins mediated transport R-HSA-382556
Hh mutants are degraded by ERAD R-HSA-5362768
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Disease R-HSA-1643685
Degradation of GLI2 by the proteasome R-HSA-5610783
Interleukin-1 family signaling R-HSA-446652
Nervous system development R-HSA-9675108
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Metaphase and Anaphase R-HSA-2555396
PCP/CE pathway R-HSA-4086400
Cell Cycle R-HSA-1640170
Neddylation R-HSA-8951664
Interleukin-1 signaling R-HSA-9020702
M Phase R-HSA-68886
Mitotic Anaphase R-HSA-68882
Signal Transduction R-HSA-162582
DNA Replication R-HSA-69306
Defective CFTR causes cystic fibrosis R-HSA-5678895
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Stabilization of p53 R-HSA-69541
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
Hedgehog 'off' state R-HSA-5610787
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Host Interactions of HIV factors R-HSA-162909
Orc1 removal from chromatin R-HSA-68949
Asymmetric localization of PCP proteins R-HSA-4608870
Innate Immune System R-HSA-168249
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular responses to stimuli R-HSA-8953897
Signaling by Hedgehog R-HSA-5358351
Vif-mediated degradation of APOBEC3G R-HSA-180585
Generic Transcription Pathway R-HSA-212436
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RNA Polymerase II Transcription R-HSA-73857
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle Checkpoints R-HSA-69620
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by NOTCH4 R-HSA-9013694
G1/S Transition R-HSA-69206
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle, Mitotic R-HSA-69278
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of polyamines R-HSA-351202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CLEC7A (Dectin-1) signaling R-HSA-5607764
Ub-specific processing proteases R-HSA-5689880
Cytokine Signaling in Immune system R-HSA-1280215
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
PTEN Regulation R-HSA-6807070
Assembly of the pre-replicative complex R-HSA-68867
G2/M Checkpoints R-HSA-69481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular response to chemical stress R-HSA-9711123
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of amino acids and derivatives R-HSA-71291
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Beta-catenin independent WNT signaling R-HSA-3858494
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stress R-HSA-2262752
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G1/S DNA Damage Checkpoints R-HSA-69615
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of AXIN R-HSA-4641257
Innate Immune System R-HSA-168249
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Synthesis of DNA R-HSA-69239
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of NF-kappaB in B cells R-HSA-1169091
G2/M Transition R-HSA-69275
Metabolism of proteins R-HSA-392499
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Orc1 removal from chromatin R-HSA-68949
PCP/CE pathway R-HSA-4086400
Neddylation R-HSA-8951664
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic G2-G2/M phases R-HSA-453274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vif-mediated degradation of APOBEC3G R-HSA-180585
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to hypoxia R-HSA-1234174
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by NOTCH R-HSA-157118
Interleukin-1 family signaling R-HSA-446652
Cellular response to chemical stress R-HSA-9711123
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Switching of origins to a post-replicative state R-HSA-69052
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G2/M Checkpoints R-HSA-69481
PTEN Regulation R-HSA-6807070
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle R-HSA-1640170
Hedgehog 'on' state R-HSA-5632684
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of DVL R-HSA-4641258
Stabilization of p53 R-HSA-69541
Interleukin-1 signaling R-HSA-9020702
Signaling by Hedgehog R-HSA-5358351
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G1/S Transition R-HSA-69206
HIV Infection R-HSA-162906
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RAF/MAP kinase cascade R-HSA-5673001
Assembly of the pre-replicative complex R-HSA-68867
Programmed Cell Death R-HSA-5357801
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX3 R-HSA-8878159
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RNA Polymerase II Transcription R-HSA-73857
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ABC transporter disorders R-HSA-5619084
Mitotic Anaphase R-HSA-68882
Nervous system development R-HSA-9675108
DNA Replication R-HSA-69306
Transcriptional regulation by RUNX2 R-HSA-8878166
ABC-family proteins mediated transport R-HSA-382556
MAPK family signaling cascades R-HSA-5683057
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Separation of Sister Chromatids R-HSA-2467813
Regulation of PTEN stability and activity R-HSA-8948751
TCR signaling R-HSA-202403
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream TCR signaling R-HSA-202424
Apoptosis R-HSA-109581
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
S Phase R-HSA-69242
Signaling by ROBO receptors R-HSA-376176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of expression of SLITs and ROBOs R-HSA-9010553
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle, Mitotic R-HSA-69278
Axon guidance R-HSA-422475
Antigen processing-Cross presentation R-HSA-1236975
ER-Phagosome pathway R-HSA-1236974
Regulation of RUNX3 expression and activity R-HSA-8941858
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'off' state R-HSA-5610787
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
KEAP1-NFE2L2 pathway R-HSA-9755511
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle Checkpoints R-HSA-69620
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Metabolism of RNA R-HSA-8953854
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Infectious disease R-HSA-5663205
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
Asymmetric localization of PCP proteins R-HSA-4608870
DNA Replication Pre-Initiation R-HSA-69002
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cyclin E associated events during G1/S transition R-HSA-69202
Intracellular signaling by second messengers R-HSA-9006925
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
Hh mutants abrogate ligand secretion R-HSA-5387390
Vpu mediated degradation of CD4 R-HSA-180534
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stress R-HSA-2262752
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Disease R-HSA-1643685
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH4 R-HSA-9013694
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ub-specific processing proteases R-HSA-5689880
Regulation of Apoptosis R-HSA-169911
Gene expression (Transcription) R-HSA-74160
Metabolism of polyamines R-HSA-351202
TCF dependent signaling in response to WNT R-HSA-201681
FCERI mediated NF-kB activation R-HSA-2871837
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RAS by GAPs R-HSA-5658442
Deubiquitination R-HSA-5688426
Metabolism R-HSA-1430728
M Phase R-HSA-68886
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by WNT R-HSA-195721
Transport of small molecules R-HSA-382551
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Adaptive Immune System R-HSA-1280218
Ub-specific processing proteases R-HSA-5689880
Regulation of RAS by GAPs R-HSA-5658442
Axon guidance R-HSA-422475
G2/M Transition R-HSA-69275
G1/S DNA Damage Checkpoints R-HSA-69615
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by Interleukins R-HSA-449147
Separation of Sister Chromatids R-HSA-2467813
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Cellular responses to stimuli R-HSA-8953897
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic G2-G2/M phases R-HSA-453274
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
DNA Replication R-HSA-69306
Vif-mediated degradation of APOBEC3G R-HSA-180585
Assembly of the pre-replicative complex R-HSA-68867
Cell Cycle, Mitotic R-HSA-69278
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants are degraded by ERAD R-HSA-5362768
Infectious disease R-HSA-5663205
ER-Phagosome pathway R-HSA-1236974
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by WNT R-HSA-195721
UCH proteinases R-HSA-5689603
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Apoptosis R-HSA-109581
RAF/MAP kinase cascade R-HSA-5673001
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of PTEN stability and activity R-HSA-8948751
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Beta-catenin independent WNT signaling R-HSA-3858494
Host Interactions of HIV factors R-HSA-162909
Mitotic G1 phase and G1/S transition R-HSA-453279
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Adaptive Immune System R-HSA-1280218
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Antigen processing-Cross presentation R-HSA-1236975
Signaling by ROBO receptors R-HSA-376176
Class I MHC mediated antigen processing & presentation R-HSA-983169
Transport of small molecules R-HSA-382551
Degradation of AXIN R-HSA-4641257
Disorders of transmembrane transporters R-HSA-5619115
Immune System R-HSA-168256
G1/S Transition R-HSA-69206
Metabolism of amino acids and derivatives R-HSA-71291
DNA Replication Pre-Initiation R-HSA-69002
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Neddylation R-HSA-8951664
TCR signaling R-HSA-202403
HIV Infection R-HSA-162906
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of polyamines R-HSA-351202
Developmental Biology R-HSA-1266738
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'on' state R-HSA-5632684
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PTEN Regulation R-HSA-6807070
G2/M Checkpoints R-HSA-69481
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of GLI1 by the proteasome R-HSA-5610780
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle Checkpoints R-HSA-69620
Cytokine Signaling in Immune system R-HSA-1280215
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of RNA R-HSA-8953854
Cyclin E associated events during G1/S transition R-HSA-69202
Interleukin-1 signaling R-HSA-9020702
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
RNA Polymerase II Transcription R-HSA-73857
S Phase R-HSA-69242
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by NOTCH R-HSA-157118
Cell Cycle R-HSA-1640170
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Deubiquitination R-HSA-5688426
Stabilization of p53 R-HSA-69541
Downstream TCR signaling R-HSA-202424
Innate Immune System R-HSA-168249
Regulation of RUNX3 expression and activity R-HSA-8941858
Activation of NF-kappaB in B cells R-HSA-1169091
Post-translational protein modification R-HSA-597592
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog ligand biogenesis R-HSA-5358346
Interleukin-1 family signaling R-HSA-446652
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Hedgehog R-HSA-5358351
Intracellular signaling by second messengers R-HSA-9006925
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Synthesis of DNA R-HSA-69239
Regulation of mitotic cell cycle R-HSA-453276
Cellular response to chemical stress R-HSA-9711123
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of Apoptosis R-HSA-169911
Asymmetric localization of PCP proteins R-HSA-4608870
M Phase R-HSA-68886
Metabolism R-HSA-1430728
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of DVL R-HSA-4641258
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Metaphase and Anaphase R-HSA-2555396
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stress R-HSA-2262752
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FCERI mediated NF-kB activation R-HSA-2871837
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disease R-HSA-1643685
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Hedgehog R-HSA-5358351
Cytokine Signaling in Immune system R-HSA-1280215
ER-Phagosome pathway R-HSA-1236974
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX3 R-HSA-8878159
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by NOTCH4 R-HSA-9013694
Metabolism R-HSA-1430728
Metabolism of RNA R-HSA-8953854
Antigen processing-Cross presentation R-HSA-1236975
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of proteins R-HSA-392499
ABC transporter disorders R-HSA-5619084
Infectious disease R-HSA-5663205
Downstream TCR signaling R-HSA-202424
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Disease R-HSA-1643685
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by WNT R-HSA-195721
Separation of Sister Chromatids R-HSA-2467813
Deubiquitination R-HSA-5688426
Signaling by ROBO receptors R-HSA-376176
G2/M Checkpoints R-HSA-69481
S Phase R-HSA-69242
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Defective CFTR causes cystic fibrosis R-HSA-5678895
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCR signaling R-HSA-202403
Regulation of expression of SLITs and ROBOs R-HSA-9010553
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1 DNA Damage Response R-HSA-69563
Gene expression (Transcription) R-HSA-74160
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic Anaphase R-HSA-68882
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hh mutants are degraded by ERAD R-HSA-5362768
Vif-mediated degradation of APOBEC3G R-HSA-180585
Asymmetric localization of PCP proteins R-HSA-4608870
DNA Replication Pre-Initiation R-HSA-69002
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog ligand biogenesis R-HSA-5358346
Post-translational protein modification R-HSA-597592
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
HIV Infection R-HSA-162906
Mitotic G2-G2/M phases R-HSA-453274
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cell Cycle, Mitotic R-HSA-69278
Cellular response to chemical stress R-HSA-9711123
Generic Transcription Pathway R-HSA-212436
Mitotic G1 phase and G1/S transition R-HSA-453279
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK1/MAPK3 signaling R-HSA-5684996
Beta-catenin independent WNT signaling R-HSA-3858494
M Phase R-HSA-68886
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of Apoptosis R-HSA-169911
Assembly of the pre-replicative complex R-HSA-68867
Cell Cycle Checkpoints R-HSA-69620
Axon guidance R-HSA-422475
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
PCP/CE pathway R-HSA-4086400
Cellular responses to stress R-HSA-2262752
Regulation of RAS by GAPs R-HSA-5658442
Programmed Cell Death R-HSA-5357801
ABC-family proteins mediated transport R-HSA-382556
Host Interactions of HIV factors R-HSA-162909
Intracellular signaling by second messengers R-HSA-9006925
Interleukin-1 family signaling R-HSA-446652
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Innate Immune System R-HSA-168249
Cell Cycle R-HSA-1640170
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'on' state R-HSA-5632684
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Neddylation R-HSA-8951664
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'off' state R-HSA-5610787
G1/S Transition R-HSA-69206
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of DVL R-HSA-4641258
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Metaphase and Anaphase R-HSA-2555396
Interleukin-1 signaling R-HSA-9020702
Transport of small molecules R-HSA-382551
Developmental Biology R-HSA-1266738
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of polyamines R-HSA-351202
Nervous system development R-HSA-9675108
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Stabilization of p53 R-HSA-69541
Degradation of AXIN R-HSA-4641257
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vpu mediated degradation of CD4 R-HSA-180534
Activation of NF-kappaB in B cells R-HSA-1169091
Apoptosis R-HSA-109581
Synthesis of DNA R-HSA-69239
Signaling by NOTCH R-HSA-157118
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mitotic cell cycle R-HSA-453276
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI1 by the proteasome R-HSA-5610780
Switching of origins to a post-replicative state R-HSA-69052
G2/M Transition R-HSA-69275
RNA Polymerase II Transcription R-HSA-73857
DNA Replication R-HSA-69306
Degradation of beta-catenin by the destruction complex R-HSA-195253
Orc1 removal from chromatin R-HSA-68949
PIP3 activates AKT signaling R-HSA-1257604
Disorders of transmembrane transporters R-HSA-5619115
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Interleukins R-HSA-449147
UCH proteinases R-HSA-5689603
PTEN Regulation R-HSA-6807070
Degradation of GLI2 by the proteasome R-HSA-5610783
Stabilization of p53 R-HSA-69541
Post-translational protein modification R-HSA-597592
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Programmed Cell Death R-HSA-5357801
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Anaphase R-HSA-68882
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog ligand biogenesis R-HSA-5358346
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Assembly of the pre-replicative complex R-HSA-68867
Switching of origins to a post-replicative state R-HSA-69052
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of RNA R-HSA-8953854
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hedgehog 'on' state R-HSA-5632684
KEAP1-NFE2L2 pathway R-HSA-9755511
PTEN Regulation R-HSA-6807070
UCH proteinases R-HSA-5689603
Regulation of Apoptosis R-HSA-169911
Signaling by NOTCH R-HSA-157118
G2/M Checkpoints R-HSA-69481
Separation of Sister Chromatids R-HSA-2467813
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Intracellular signaling by second messengers R-HSA-9006925
G1/S DNA Damage Checkpoints R-HSA-69615
TCF dependent signaling in response to WNT R-HSA-201681
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of RUNX3 expression and activity R-HSA-8941858
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of polyamines R-HSA-351202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Adaptive Immune System R-HSA-1280218
PCP/CE pathway R-HSA-4086400
Cell Cycle R-HSA-1640170
Ub-specific processing proteases R-HSA-5689880
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Interleukin-1 signaling R-HSA-9020702
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing-Cross presentation R-HSA-1236975
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Metaphase and Anaphase R-HSA-2555396
Gene expression (Transcription) R-HSA-74160
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by WNT R-HSA-195721
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stress R-HSA-2262752
Cell Cycle, Mitotic R-HSA-69278
Innate Immune System R-HSA-168249
Defective CFTR causes cystic fibrosis R-HSA-5678895
M Phase R-HSA-68886
Signaling by Hedgehog R-HSA-5358351
Immune System R-HSA-168256
Downstream TCR signaling R-HSA-202424
Signal Transduction R-HSA-162582
Apoptosis R-HSA-109581
Cell Cycle Checkpoints R-HSA-69620
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Asymmetric localization of PCP proteins R-HSA-4608870
PIP3 activates AKT signaling R-HSA-1257604
G2/M Transition R-HSA-69275
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RAS by GAPs R-HSA-5658442
TCR signaling R-HSA-202403
C-type lectin receptors (CLRs) R-HSA-5621481
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Deubiquitination R-HSA-5688426
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular response to chemical stress R-HSA-9711123
G1/S Transition R-HSA-69206
Cellular responses to stimuli R-HSA-8953897
Nervous system development R-HSA-9675108
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
Negative regulation of NOTCH4 signaling R-HSA-9604323
MAPK family signaling cascades R-HSA-5683057
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'off' state R-HSA-5610787
Orc1 removal from chromatin R-HSA-68949
Infectious disease R-HSA-5663205
Synthesis of DNA R-HSA-69239
Hh mutants abrogate ligand secretion R-HSA-5387390
Disease R-HSA-1643685
Host Interactions of HIV factors R-HSA-162909
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Developmental Biology R-HSA-1266738
Degradation of DVL R-HSA-4641258
Disorders of transmembrane transporters R-HSA-5619115
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RAF/MAP kinase cascade R-HSA-5673001
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic G2-G2/M phases R-HSA-453274
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular response to hypoxia R-HSA-1234174
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of proteins R-HSA-392499
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signaling by Interleukins R-HSA-449147
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Generic Transcription Pathway R-HSA-212436
Degradation of AXIN R-HSA-4641257
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
CLEC7A (Dectin-1) signaling R-HSA-5607764
ABC-family proteins mediated transport R-HSA-382556
HIV Infection R-HSA-162906
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ER-Phagosome pathway R-HSA-1236974
Regulation of mitotic cell cycle R-HSA-453276
Interleukin-1 family signaling R-HSA-446652
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by ROBO receptors R-HSA-376176
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism R-HSA-1430728
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by NOTCH4 R-HSA-9013694
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of PTEN stability and activity R-HSA-8948751
Transport of small molecules R-HSA-382551
Axon guidance R-HSA-422475
RNA Polymerase II Transcription R-HSA-73857
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Independent DNA Damage Response R-HSA-69610
Beta-catenin independent WNT signaling R-HSA-3858494
Ub-specific processing proteases R-HSA-5689880
Synthesis of DNA R-HSA-69239
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Vif-mediated degradation of APOBEC3G R-HSA-180585
Adaptive Immune System R-HSA-1280218
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK family signaling cascades R-HSA-5683057
TCF dependent signaling in response to WNT R-HSA-201681
Class I MHC mediated antigen processing & presentation R-HSA-983169
Infectious disease R-HSA-5663205
Intracellular signaling by second messengers R-HSA-9006925
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
HIV Infection R-HSA-162906
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication R-HSA-69306
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
ABC transporter disorders R-HSA-5619084
ER-Phagosome pathway R-HSA-1236974
Signaling by NOTCH4 R-HSA-9013694
Neddylation R-HSA-8951664
G2/M Checkpoints R-HSA-69481
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of proteins R-HSA-392499
Hedgehog 'on' state R-HSA-5632684
PIP3 activates AKT signaling R-HSA-1257604
Downstream TCR signaling R-HSA-202424
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G1/S Transition R-HSA-69206
PCP/CE pathway R-HSA-4086400
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G2-G2/M phases R-HSA-453274
Stabilization of p53 R-HSA-69541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stimuli R-HSA-8953897
Metabolism of polyamines R-HSA-351202
Mitotic Metaphase and Anaphase R-HSA-2555396
Innate Immune System R-HSA-168249
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of mitotic cell cycle R-HSA-453276
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by ROBO receptors R-HSA-376176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Mitotic G1 phase and G1/S transition R-HSA-453279
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signal Transduction R-HSA-162582
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX1 R-HSA-8878171
Orc1 removal from chromatin R-HSA-68949
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 signaling R-HSA-9020702
Degradation of DVL R-HSA-4641258
Nervous system development R-HSA-9675108
Metabolism of RNA R-HSA-8953854
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic Anaphase R-HSA-68882
p53-Dependent G1 DNA Damage Response R-HSA-69563
Antigen processing-Cross presentation R-HSA-1236975
Interleukin-1 family signaling R-HSA-446652
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by NOTCH R-HSA-157118
RNA Polymerase II Transcription R-HSA-73857
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of PTEN stability and activity R-HSA-8948751
Transport of small molecules R-HSA-382551
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of AXIN R-HSA-4641257
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
Cytokine Signaling in Immune system R-HSA-1280215
Programmed Cell Death R-HSA-5357801
ABC-family proteins mediated transport R-HSA-382556
Metabolism R-HSA-1430728
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle, Mitotic R-HSA-69278
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of Apoptosis R-HSA-169911
Signaling by Hedgehog R-HSA-5358351
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of RUNX2 expression and activity R-HSA-8939902
DNA Replication Pre-Initiation R-HSA-69002
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
FCERI mediated NF-kB activation R-HSA-2871837
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of beta-catenin by the destruction complex R-HSA-195253
PTEN Regulation R-HSA-6807070
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
Generic Transcription Pathway R-HSA-212436
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Switching of origins to a post-replicative state R-HSA-69052
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular response to chemical stress R-HSA-9711123
Cellular response to hypoxia R-HSA-1234174
Cellular responses to stress R-HSA-2262752
Hedgehog 'off' state R-HSA-5610787
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle Checkpoints R-HSA-69620
M Phase R-HSA-68886
MAPK1/MAPK3 signaling R-HSA-5684996
Apoptosis R-HSA-109581
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Axon guidance R-HSA-422475
Host Interactions of HIV factors R-HSA-162909
Degradation of GLI1 by the proteasome R-HSA-5610780
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
S Phase R-HSA-69242
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
TCR signaling R-HSA-202403
Assembly of the pre-replicative complex R-HSA-68867
Nuclear events mediated by NFE2L2 R-HSA-9759194
CLEC7A (Dectin-1) signaling R-HSA-5607764
Immune System R-HSA-168256
Ub-specific processing proteases R-HSA-5689880
Host Interactions of HIV factors R-HSA-162909
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to chemical stress R-HSA-9711123
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic Anaphase R-HSA-68882
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle R-HSA-1640170
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Metabolism of polyamines R-HSA-351202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by NOTCH4 R-HSA-9013694
MAPK1/MAPK3 signaling R-HSA-5684996
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PCP/CE pathway R-HSA-4086400
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Defective CFTR causes cystic fibrosis R-HSA-5678895
ER-Phagosome pathway R-HSA-1236974
DNA Replication R-HSA-69306
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of GLI2 by the proteasome R-HSA-5610783
Vif-mediated degradation of APOBEC3G R-HSA-180585
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Gene expression (Transcription) R-HSA-74160
Infectious disease R-HSA-5663205
Innate Immune System R-HSA-168249
Cell Cycle Checkpoints R-HSA-69620
Hedgehog ligand biogenesis R-HSA-5358346
p53-Dependent G1 DNA Damage Response R-HSA-69563
Neddylation R-HSA-8951664
Signaling by NOTCH R-HSA-157118
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
S Phase R-HSA-69242
Hedgehog 'off' state R-HSA-5610787
Cyclin E associated events during G1/S transition R-HSA-69202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
M Phase R-HSA-68886
Regulation of Apoptosis R-HSA-169911
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Orc1 removal from chromatin R-HSA-68949
Apoptosis R-HSA-109581
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Asymmetric localization of PCP proteins R-HSA-4608870
Disease R-HSA-1643685
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK6/MAPK4 signaling R-HSA-5687128
Axon guidance R-HSA-422475
ABC-family proteins mediated transport R-HSA-382556
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of DVL R-HSA-4641258
Metabolism of amino acids and derivatives R-HSA-71291
G2/M Checkpoints R-HSA-69481
Disorders of transmembrane transporters R-HSA-5619115
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'on' state R-HSA-5632684
ABC transporter disorders R-HSA-5619084
Programmed Cell Death R-HSA-5357801
Metabolism R-HSA-1430728
PIP3 activates AKT signaling R-HSA-1257604
Separation of Sister Chromatids R-HSA-2467813
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by WNT R-HSA-195721
Nuclear events mediated by NFE2L2 R-HSA-9759194
Beta-catenin independent WNT signaling R-HSA-3858494
Nervous system development R-HSA-9675108
Regulation of RAS by GAPs R-HSA-5658442
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 signaling R-HSA-9020702
PTEN Regulation R-HSA-6807070
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Activation of NF-kappaB in B cells R-HSA-1169091
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 family signaling R-HSA-446652
Signal Transduction R-HSA-162582
Hh mutants abrogate ligand secretion R-HSA-5387390
G1/S Transition R-HSA-69206
Metabolism of proteins R-HSA-392499
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stress R-HSA-2262752
Cellular response to hypoxia R-HSA-1234174
Transport of small molecules R-HSA-382551
Post-translational protein modification R-HSA-597592
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
KEAP1-NFE2L2 pathway R-HSA-9755511
G2/M Transition R-HSA-69275
Signaling by Hedgehog R-HSA-5358351
Degradation of AXIN R-HSA-4641257
Transcriptional regulation by RUNX3 R-HSA-8878159
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Generic Transcription Pathway R-HSA-212436
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G1/S DNA Damage Checkpoints R-HSA-69615
TCR signaling R-HSA-202403
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hh mutants are degraded by ERAD R-HSA-5362768
Antigen processing-Cross presentation R-HSA-1236975
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of RNA R-HSA-8953854
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Downstream TCR signaling R-HSA-202424
MAPK family signaling cascades R-HSA-5683057
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Negative regulation of NOTCH4 signaling R-HSA-9604323
Synthesis of DNA R-HSA-69239
Stabilization of p53 R-HSA-69541
Transcriptional regulation by RUNX2 R-HSA-8878166
RAF/MAP kinase cascade R-HSA-5673001
Vpu mediated degradation of CD4 R-HSA-180534
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Signaling by ROBO receptors R-HSA-376176
HIV Infection R-HSA-162906
Cellular responses to stimuli R-HSA-8953897
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic Metaphase and Anaphase R-HSA-2555396
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic G2-G2/M phases R-HSA-453274
Adaptive Immune System R-HSA-1280218
RNA Polymerase II Transcription R-HSA-73857
FCERI mediated NF-kB activation R-HSA-2871837
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cytokine Signaling in Immune system R-HSA-1280215
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of PTEN stability and activity R-HSA-8948751
Switching of origins to a post-replicative state R-HSA-69052
Cellular responses to stimuli R-HSA-8953897
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'off' state R-HSA-5610787
Disorders of transmembrane transporters R-HSA-5619115
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic G2-G2/M phases R-HSA-453274
p53-Dependent G1 DNA Damage Response R-HSA-69563
M Phase R-HSA-68886
Intracellular signaling by second messengers R-HSA-9006925
Beta-catenin independent WNT signaling R-HSA-3858494
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cell Cycle Checkpoints R-HSA-69620
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signal Transduction R-HSA-162582
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TCF dependent signaling in response to WNT R-HSA-201681
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream TCR signaling R-HSA-202424
Neddylation R-HSA-8951664
Deubiquitination R-HSA-5688426
Signaling by NOTCH R-HSA-157118
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle, Mitotic R-HSA-69278
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of mitotic cell cycle R-HSA-453276
Asymmetric localization of PCP proteins R-HSA-4608870
Cyclin E associated events during G1/S transition R-HSA-69202
Immune System R-HSA-168256
DNA Replication R-HSA-69306
Mitotic Anaphase R-HSA-68882
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of AXIN R-HSA-4641257
Metabolism of proteins R-HSA-392499
Cellular response to hypoxia R-HSA-1234174
Disease R-HSA-1643685
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent DNA Damage Response R-HSA-69610
UCH proteinases R-HSA-5689603
ABC-family proteins mediated transport R-HSA-382556
Ub-specific processing proteases R-HSA-5689880
Transcriptional regulation by RUNX1 R-HSA-8878171
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of polyamines R-HSA-351202
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
ER-Phagosome pathway R-HSA-1236974
Metabolism of amino acids and derivatives R-HSA-71291
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of PTEN stability and activity R-HSA-8948751
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Programmed Cell Death R-HSA-5357801
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Synthesis of DNA R-HSA-69239
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of expression of SLITs and ROBOs R-HSA-9010553
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
DNA Replication Pre-Initiation R-HSA-69002
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Stabilization of p53 R-HSA-69541
MAPK family signaling cascades R-HSA-5683057
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TCR signaling R-HSA-202403
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
RAF/MAP kinase cascade R-HSA-5673001
Signaling by ROBO receptors R-HSA-376176
G2/M Transition R-HSA-69275
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Nervous system development R-HSA-9675108
G2/M Checkpoints R-HSA-69481
Innate Immune System R-HSA-168249
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing-Cross presentation R-HSA-1236975
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Host Interactions of HIV factors R-HSA-162909
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
Transport of small molecules R-HSA-382551
Interleukin-1 signaling R-HSA-9020702
Adaptive Immune System R-HSA-1280218
PTEN Regulation R-HSA-6807070
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Generic Transcription Pathway R-HSA-212436
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ABC transporter disorders R-HSA-5619084
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of DVL R-HSA-4641258
Metabolism of RNA R-HSA-8953854
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Post-translational protein modification R-HSA-597592
Hedgehog ligand biogenesis R-HSA-5358346
Hedgehog 'on' state R-HSA-5632684
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Infectious disease R-HSA-5663205
Degradation of GLI2 by the proteasome R-HSA-5610783
Orc1 removal from chromatin R-HSA-68949
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by WNT R-HSA-195721
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
G1/S Transition R-HSA-69206
Signaling by NOTCH4 R-HSA-9013694
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 family signaling R-HSA-446652
Signaling by Interleukins R-HSA-449147
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of GLI1 by the proteasome R-HSA-5610780
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of Apoptosis R-HSA-169911
PCP/CE pathway R-HSA-4086400
Separation of Sister Chromatids R-HSA-2467813
Activation of NF-kappaB in B cells R-HSA-1169091

Expression Atlas ENSG00000277791
NCBI gene (formerly Entrezgene) 5691
GeneCards 9540
HGNC Symbol HGNC:9540
MIM gene 602176
UniProtKB Gene Name P49720
WikiGene 5691
Gene: KCNK9
Ensembl ID : ENSG00000169427
Description: potassium two pore domain channel subfamily K member 9
Gene Synonyms: K2P9.1,TASK-3,TASK3
6 APIs:
215 Possible Orthologues:

Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Tandem pore domain potassium channels R-HSA-1296346
Potassium Channels R-HSA-1296071
Neuronal System R-HSA-112316
Phase 4 - resting membrane potential R-HSA-5576886
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Phase 4 - resting membrane potential R-HSA-5576886
Potassium Channels R-HSA-1296071
Cardiac conduction R-HSA-5576891
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Muscle contraction R-HSA-397014
Tandem pore domain potassium channels R-HSA-1296346
Neuronal System R-HSA-112316
Tandem pore domain potassium channels R-HSA-1296346
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Potassium Channels R-HSA-1296071
Neuronal System R-HSA-112316
Phase 4 - resting membrane potential R-HSA-5576886
Potassium Channels R-HSA-1296071
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Tandem pore domain potassium channels R-HSA-1296346
Phase 4 - resting membrane potential R-HSA-5576886
Neuronal System R-HSA-112316
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Neuronal System R-HSA-112316
Potassium Channels R-HSA-1296071
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Cardiac conduction R-HSA-5576891
Phase 4 - resting membrane potential R-HSA-5576886
Tandem pore domain potassium channels R-HSA-1296346
Muscle contraction R-HSA-397014
Phase 4 - resting membrane potential R-HSA-5576886
Neuronal System R-HSA-112316
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Potassium Channels R-HSA-1296071
Tandem pore domain potassium channels R-HSA-1296346
Neuronal System R-HSA-112316
Cardiac conduction R-HSA-5576891
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Phase 4 - resting membrane potential R-HSA-5576886
Muscle contraction R-HSA-397014
Potassium Channels R-HSA-1296071
Tandem pore domain potassium channels R-HSA-1296346
Neuronal System R-HSA-112316
Muscle contraction R-HSA-397014
Potassium Channels R-HSA-1296071
Phase 4 - resting membrane potential R-HSA-5576886
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Cardiac conduction R-HSA-5576891
Tandem pore domain potassium channels R-HSA-1296346
Phase 4 - resting membrane potential R-HSA-5576886
Tandem pore domain potassium channels R-HSA-1296346
Muscle contraction R-HSA-397014
Potassium Channels R-HSA-1296071
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Cardiac conduction R-HSA-5576891
Neuronal System R-HSA-112316
Phase 4 - resting membrane potential R-HSA-5576886
Muscle contraction R-HSA-397014
Tandem pore domain potassium channels R-HSA-1296346
Neuronal System R-HSA-112316
Potassium Channels R-HSA-1296071
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Cardiac conduction R-HSA-5576891

Expression Atlas ENSG00000169427
LRG display in Ensembl gene LRG_1042
NCBI gene (formerly Entrezgene) 51305
GeneCards 6283
HGNC Symbol HGNC:6283
MIM gene 605874
MIM morbid 612292
UniProtKB Gene Name Q9NPC2
WikiGene 51305
Gene: KCNK3
Ensembl ID : ENSG00000171303
Description: potassium two pore domain channel subfamily K member 3
Gene Synonyms: K2P3.1,TASK,TASK-1,TASK1
6 APIs:
202 Possible Orthologues:

Neuronal System R-HSA-112316
Potassium Channels R-HSA-1296071
Muscle contraction R-HSA-397014
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Tandem pore domain potassium channels R-HSA-1296346
Phase 4 - resting membrane potential R-HSA-5576886
Cardiac conduction R-HSA-5576891
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Potassium Channels R-HSA-1296071
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Tandem pore domain potassium channels R-HSA-1296346
Neuronal System R-HSA-112316
Phase 4 - resting membrane potential R-HSA-5576886
Tandem pore domain potassium channels R-HSA-1296346
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Potassium Channels R-HSA-1296071
Phase 4 - resting membrane potential R-HSA-5576886
Neuronal System R-HSA-112316
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Phase 4 - resting membrane potential R-HSA-5576886
Potassium Channels R-HSA-1296071
Neuronal System R-HSA-112316
Cardiac conduction R-HSA-5576891
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Tandem pore domain potassium channels R-HSA-1296346
Potassium Channels R-HSA-1296071
Neuronal System R-HSA-112316
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Cardiac conduction R-HSA-5576891
Phase 4 - resting membrane potential R-HSA-5576886
Tandem pore domain potassium channels R-HSA-1296346
Muscle contraction R-HSA-397014
Tandem pore domain potassium channels R-HSA-1296346
Cardiac conduction R-HSA-5576891
Potassium Channels R-HSA-1296071
Phase 4 - resting membrane potential R-HSA-5576886
Neuronal System R-HSA-112316
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Muscle contraction R-HSA-397014
Potassium Channels R-HSA-1296071
Tandem pore domain potassium channels R-HSA-1296346
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Neuronal System R-HSA-112316
Phase 4 - resting membrane potential R-HSA-5576886
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Muscle contraction R-HSA-397014
Potassium Channels R-HSA-1296071
Tandem pore domain potassium channels R-HSA-1296346
Neuronal System R-HSA-112316
Phase 4 - resting membrane potential R-HSA-5576886
Cardiac conduction R-HSA-5576891
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316
Potassium Channels R-HSA-1296071
Neuronal System R-HSA-112316
Phase 4 - resting membrane potential R-HSA-5576886
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Tandem pore domain potassium channels R-HSA-1296346

Expression Atlas ENSG00000171303
NCBI gene (formerly Entrezgene) 3777
GeneCards 6278
HGNC Symbol HGNC:6278
MIM gene 603220
MIM morbid 615344
UniProtKB Gene Name O14649
WikiGene 3777