Gene: PSMD13
Ensembl ID : ENSG00000185627
Description: proteasome 26S subunit, non-ATPase 13
Gene Synonyms: P40.5,RPN9
5 APIs:
220 Possible Orthologues:

G2/M Checkpoints R-HSA-69481
Signaling by NOTCH R-HSA-157118
Gene expression (Transcription) R-HSA-74160
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of DVL R-HSA-4641258
Stabilization of p53 R-HSA-69541
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Transcriptional regulation by RUNX3 R-HSA-8878159
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH R-HSA-157118
Regulation of Apoptosis R-HSA-169911
Interleukin-1 family signaling R-HSA-446652
MAPK1/MAPK3 signaling R-HSA-5684996
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of amino acids and derivatives R-HSA-71291
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Antigen processing-Cross presentation R-HSA-1236975
Developmental Biology R-HSA-1266738
PTEN Regulation R-HSA-6807070
G1/S Transition R-HSA-69206
Switching of origins to a post-replicative state R-HSA-69052
Programmed Cell Death R-HSA-5357801
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Anaphase R-HSA-68882
Regulation of RUNX2 expression and activity R-HSA-8939902
Cell Cycle R-HSA-1640170
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular response to hypoxia R-HSA-1234174
Assembly of the pre-replicative complex R-HSA-68867
Disease R-HSA-1643685
TCR signaling R-HSA-202403
Cytokine Signaling in Immune system R-HSA-1280215
Post-translational protein modification R-HSA-597592
Metabolism R-HSA-1430728
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Apoptosis R-HSA-109581
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vif-mediated degradation of APOBEC3G R-HSA-180585
PCP/CE pathway R-HSA-4086400
Deubiquitination R-HSA-5688426
Cellular response to chemical stress R-HSA-9711123
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signal Transduction R-HSA-162582
Hedgehog 'off' state R-HSA-5610787
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ER-Phagosome pathway R-HSA-1236974
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transport of small molecules R-HSA-382551
Cellular responses to stimuli R-HSA-8953897
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic G1 phase and G1/S transition R-HSA-453279
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of GLI2 by the proteasome R-HSA-5610783
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
Neddylation R-HSA-8951664
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of polyamines R-HSA-351202
Activation of NF-kappaB in B cells R-HSA-1169091
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ub-specific processing proteases R-HSA-5689880
M Phase R-HSA-68886
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK family signaling cascades R-HSA-5683057
Synthesis of DNA R-HSA-69239
Neutrophil degranulation R-HSA-6798695
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Signaling by Interleukins R-HSA-449147
Metabolism of proteins R-HSA-392499
G2/M Transition R-HSA-69275
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog 'on' state R-HSA-5632684
Infectious disease R-HSA-5663205
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of RNA R-HSA-8953854
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Hedgehog ligand biogenesis R-HSA-5358346
FCERI mediated NF-kB activation R-HSA-2871837
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of PTEN stability and activity R-HSA-8948751
S Phase R-HSA-69242
Axon guidance R-HSA-422475
Hh mutants are degraded by ERAD R-HSA-5362768
Nervous system development R-HSA-9675108
UCH proteinases R-HSA-5689603
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stress R-HSA-2262752
Downstream TCR signaling R-HSA-202424
Gene expression (Transcription) R-HSA-74160
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by ROBO receptors R-HSA-376176
Regulation of mitotic cell cycle R-HSA-453276
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Separation of Sister Chromatids R-HSA-2467813
Host Interactions of HIV factors R-HSA-162909
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of NOTCH4 signaling R-HSA-9604323
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G2-G2/M phases R-HSA-453274
ABC transporter disorders R-HSA-5619084
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Adaptive Immune System R-HSA-1280218
Signaling by WNT R-HSA-195721
Signaling by Hedgehog R-HSA-5358351
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Independent DNA Damage Response R-HSA-69610
Defective CFTR causes cystic fibrosis R-HSA-5678895
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
HIV Infection R-HSA-162906
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH4 R-HSA-9013694
G1/S DNA Damage Checkpoints R-HSA-69615
ABC-family proteins mediated transport R-HSA-382556
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hh mutants abrogate ligand secretion R-HSA-5387390
Disorders of transmembrane transporters R-HSA-5619115
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
Innate Immune System R-HSA-168249
Interleukin-1 signaling R-HSA-9020702
Mitotic Metaphase and Anaphase R-HSA-2555396
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of AXIN R-HSA-4641257
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic Anaphase R-HSA-68882
G2/M Checkpoints R-HSA-69481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
MAPK1/MAPK3 signaling R-HSA-5684996
Ub-specific processing proteases R-HSA-5689880
Vpu mediated degradation of CD4 R-HSA-180534
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of PTEN stability and activity R-HSA-8948751
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK6/MAPK4 signaling R-HSA-5687128
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of DVL R-HSA-4641258
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants are degraded by ERAD R-HSA-5362768
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by ROBO receptors R-HSA-376176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX2 R-HSA-8878166
Defective CFTR causes cystic fibrosis R-HSA-5678895
Post-translational protein modification R-HSA-597592
Neutrophil degranulation R-HSA-6798695
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RAS by GAPs R-HSA-5658442
Metabolism R-HSA-1430728
Regulation of RUNX2 expression and activity R-HSA-8939902
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transport of small molecules R-HSA-382551
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Intracellular signaling by second messengers R-HSA-9006925
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Apoptosis R-HSA-109581
Immune System R-HSA-168256
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signal Transduction R-HSA-162582
TCF dependent signaling in response to WNT R-HSA-201681
PIP3 activates AKT signaling R-HSA-1257604
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Antigen processing-Cross presentation R-HSA-1236975
ABC-family proteins mediated transport R-HSA-382556
Gene expression (Transcription) R-HSA-74160
ABC transporter disorders R-HSA-5619084
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Synthesis of DNA R-HSA-69239
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic G2-G2/M phases R-HSA-453274
Beta-catenin independent WNT signaling R-HSA-3858494
HIV Infection R-HSA-162906
Degradation of GLI2 by the proteasome R-HSA-5610783
Separation of Sister Chromatids R-HSA-2467813
Signaling by NOTCH R-HSA-157118
Cellular responses to stimuli R-HSA-8953897
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Interleukin-1 signaling R-HSA-9020702
Signaling by Interleukins R-HSA-449147
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Assembly of the pre-replicative complex R-HSA-68867
Host Interactions of HIV factors R-HSA-162909
Degradation of GLI1 by the proteasome R-HSA-5610780
Cytokine Signaling in Immune system R-HSA-1280215
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of Apoptosis R-HSA-169911
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
UCH proteinases R-HSA-5689603
Axon guidance R-HSA-422475
Neddylation R-HSA-8951664
Signaling by Hedgehog R-HSA-5358351
Generic Transcription Pathway R-HSA-212436
Metabolism of polyamines R-HSA-351202
Signaling by WNT R-HSA-195721
Innate Immune System R-HSA-168249
Class I MHC mediated antigen processing & presentation R-HSA-983169
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S Transition R-HSA-69206
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hh mutants abrogate ligand secretion R-HSA-5387390
RAF/MAP kinase cascade R-HSA-5673001
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of RNA R-HSA-8953854
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Switching of origins to a post-replicative state R-HSA-69052
RNA Polymerase II Transcription R-HSA-73857
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FCERI mediated NF-kB activation R-HSA-2871837
Hedgehog 'on' state R-HSA-5632684
Degradation of beta-catenin by the destruction complex R-HSA-195253
Interleukin-1 family signaling R-HSA-446652
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mitotic cell cycle R-HSA-453276
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
G2/M Transition R-HSA-69275
Programmed Cell Death R-HSA-5357801
Cellular responses to stress R-HSA-2262752
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
Orc1 removal from chromatin R-HSA-68949
Cell Cycle Checkpoints R-HSA-69620
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cyclin E associated events during G1/S transition R-HSA-69202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular response to hypoxia R-HSA-1234174
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Disorders of transmembrane transporters R-HSA-5619115
PTEN Regulation R-HSA-6807070
Disease R-HSA-1643685
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK family signaling cascades R-HSA-5683057
ER-Phagosome pathway R-HSA-1236974
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cell Cycle R-HSA-1640170
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TCR signaling R-HSA-202403
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
M Phase R-HSA-68886
Deubiquitination R-HSA-5688426
Hedgehog 'off' state R-HSA-5610787
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PCP/CE pathway R-HSA-4086400
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
S Phase R-HSA-69242
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Stabilization of p53 R-HSA-69541
DNA Replication R-HSA-69306
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Programmed Cell Death R-HSA-5357801
Defective CFTR causes cystic fibrosis R-HSA-5678895
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH R-HSA-157118
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX3 expression and activity R-HSA-8941858
KEAP1-NFE2L2 pathway R-HSA-9755511
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
ABC transporter disorders R-HSA-5619084
C-type lectin receptors (CLRs) R-HSA-5621481
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle Checkpoints R-HSA-69620
Hh mutants are degraded by ERAD R-HSA-5362768
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI2 by the proteasome R-HSA-5610783
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TCR signaling R-HSA-202403
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of DVL R-HSA-4641258
Host Interactions of HIV factors R-HSA-162909
Switching of origins to a post-replicative state R-HSA-69052
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog ligand biogenesis R-HSA-5358346
Disease R-HSA-1643685
UCH proteinases R-HSA-5689603
MAPK family signaling cascades R-HSA-5683057
Hedgehog 'off' state R-HSA-5610787
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
TCF dependent signaling in response to WNT R-HSA-201681
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Regulation of Apoptosis R-HSA-169911
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cytokine Signaling in Immune system R-HSA-1280215
Neutrophil degranulation R-HSA-6798695
Interleukin-1 signaling R-HSA-9020702
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Innate Immune System R-HSA-168249
Cellular response to hypoxia R-HSA-1234174
Orc1 removal from chromatin R-HSA-68949
Downstream TCR signaling R-HSA-202424
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G2/M Checkpoints R-HSA-69481
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle, Mitotic R-HSA-69278
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to chemical stress R-HSA-9711123
DNA Replication Pre-Initiation R-HSA-69002
HIV Infection R-HSA-162906
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by WNT R-HSA-195721
Metabolism of proteins R-HSA-392499
Degradation of AXIN R-HSA-4641257
DNA Replication R-HSA-69306
Disorders of transmembrane transporters R-HSA-5619115
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of polyamines R-HSA-351202
Metabolism of RNA R-HSA-8953854
Apoptosis R-HSA-109581
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-1 family signaling R-HSA-446652
PTEN Regulation R-HSA-6807070
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell Cycle R-HSA-1640170
Transport of small molecules R-HSA-382551
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of RUNX2 expression and activity R-HSA-8939902
Gene expression (Transcription) R-HSA-74160
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by NOTCH4 R-HSA-9013694
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of PTEN stability and activity R-HSA-8948751
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Hedgehog R-HSA-5358351
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic Anaphase R-HSA-68882
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
S Phase R-HSA-69242
Negative regulation of NOTCH4 signaling R-HSA-9604323
CLEC7A (Dectin-1) signaling R-HSA-5607764
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Stabilization of p53 R-HSA-69541
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
Neddylation R-HSA-8951664
Metabolism R-HSA-1430728
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular responses to stimuli R-HSA-8953897
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Post-translational protein modification R-HSA-597592
Deubiquitination R-HSA-5688426
G1/S Transition R-HSA-69206
Ub-specific processing proteases R-HSA-5689880
Antigen processing-Cross presentation R-HSA-1236975
Signaling by ROBO receptors R-HSA-376176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G2-G2/M phases R-HSA-453274
Nervous system development R-HSA-9675108
Class I MHC mediated antigen processing & presentation R-HSA-983169
G2/M Transition R-HSA-69275
PCP/CE pathway R-HSA-4086400
Generic Transcription Pathway R-HSA-212436
ER-Phagosome pathway R-HSA-1236974
M Phase R-HSA-68886
ABC-family proteins mediated transport R-HSA-382556
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signal Transduction R-HSA-162582
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants abrogate ligand secretion R-HSA-5387390
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Assembly of the pre-replicative complex R-HSA-68867
Immune System R-HSA-168256
Vpu mediated degradation of CD4 R-HSA-180534
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Stabilization of p53 R-HSA-69541
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCR signaling R-HSA-202403
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by WNT R-HSA-195721
Cellular response to hypoxia R-HSA-1234174
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Apoptosis R-HSA-109581
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
G2/M Checkpoints R-HSA-69481
FCERI mediated NF-kB activation R-HSA-2871837
Cellular responses to stress R-HSA-2262752
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hh mutants are degraded by ERAD R-HSA-5362768
Downstream TCR signaling R-HSA-202424
Hh mutants abrogate ligand secretion R-HSA-5387390
Axon guidance R-HSA-422475
Nuclear events mediated by NFE2L2 R-HSA-9759194
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX3 expression and activity R-HSA-8941858
ER-Phagosome pathway R-HSA-1236974
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX3 R-HSA-8878159
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of beta-catenin by the destruction complex R-HSA-195253
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'off' state R-HSA-5610787
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Separation of Sister Chromatids R-HSA-2467813
Activation of NF-kappaB in B cells R-HSA-1169091
Deubiquitination R-HSA-5688426
DNA Replication R-HSA-69306
Signaling by ROBO receptors R-HSA-376176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Neddylation R-HSA-8951664
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
KEAP1-NFE2L2 pathway R-HSA-9755511
Beta-catenin independent WNT signaling R-HSA-3858494
Cyclin E associated events during G1/S transition R-HSA-69202
Disease R-HSA-1643685
Signaling by Hedgehog R-HSA-5358351
Metabolism of amino acids and derivatives R-HSA-71291
Switching of origins to a post-replicative state R-HSA-69052
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Host Interactions of HIV factors R-HSA-162909
G1/S DNA Damage Checkpoints R-HSA-69615
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK family signaling cascades R-HSA-5683057
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
Hedgehog ligand biogenesis R-HSA-5358346
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
HIV Infection R-HSA-162906
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing-Cross presentation R-HSA-1236975
UCH proteinases R-HSA-5689603
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Orc1 removal from chromatin R-HSA-68949
ABC-family proteins mediated transport R-HSA-382556
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of RNA R-HSA-8953854
Mitotic Anaphase R-HSA-68882
Cellular response to chemical stress R-HSA-9711123
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism R-HSA-1430728
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transport of small molecules R-HSA-382551
Developmental Biology R-HSA-1266738
PIP3 activates AKT signaling R-HSA-1257604
Assembly of the pre-replicative complex R-HSA-68867
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PCP/CE pathway R-HSA-4086400
Post-translational protein modification R-HSA-597592
Signaling by NOTCH4 R-HSA-9013694
CLEC7A (Dectin-1) signaling R-HSA-5607764
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of polyamines R-HSA-351202
S Phase R-HSA-69242
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of GLI1 by the proteasome R-HSA-5610780
Infectious disease R-HSA-5663205
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
Adaptive Immune System R-HSA-1280218
Vpu mediated degradation of CD4 R-HSA-180534
G1/S Transition R-HSA-69206
Gene expression (Transcription) R-HSA-74160
Degradation of DVL R-HSA-4641258
Asymmetric localization of PCP proteins R-HSA-4608870
ABC transporter disorders R-HSA-5619084
p53-Independent DNA Damage Response R-HSA-69610
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle R-HSA-1640170
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Synthesis of DNA R-HSA-69239
MAPK1/MAPK3 signaling R-HSA-5684996
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH R-HSA-157118
Hedgehog 'on' state R-HSA-5632684
Mitotic Metaphase and Anaphase R-HSA-2555396
TCF dependent signaling in response to WNT R-HSA-201681
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Interleukins R-HSA-449147
RAF/MAP kinase cascade R-HSA-5673001
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Programmed Cell Death R-HSA-5357801
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Interleukin-1 family signaling R-HSA-446652
Nervous system development R-HSA-9675108
Neutrophil degranulation R-HSA-6798695
Transcriptional regulation by RUNX1 R-HSA-8878171
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of mitotic cell cycle R-HSA-453276
Assembly of the pre-replicative complex R-HSA-68867
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK family signaling cascades R-HSA-5683057
Mitotic G2-G2/M phases R-HSA-453274
Degradation of AXIN R-HSA-4641257
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Transition R-HSA-69275
S Phase R-HSA-69242
Signaling by WNT R-HSA-195721
M Phase R-HSA-68886
Generic Transcription Pathway R-HSA-212436
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of GLI1 by the proteasome R-HSA-5610780
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Interleukins R-HSA-449147
Mitotic Metaphase and Anaphase R-HSA-2555396
Gene expression (Transcription) R-HSA-74160
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle R-HSA-1640170
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle, Mitotic R-HSA-69278
DNA Replication Pre-Initiation R-HSA-69002
Neutrophil degranulation R-HSA-6798695
G2/M Checkpoints R-HSA-69481
Interleukin-1 family signaling R-HSA-446652
Deubiquitination R-HSA-5688426
PIP3 activates AKT signaling R-HSA-1257604
Regulation of PTEN stability and activity R-HSA-8948751
Intracellular signaling by second messengers R-HSA-9006925
ER-Phagosome pathway R-HSA-1236974
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent DNA Damage Response R-HSA-69610
RAF/MAP kinase cascade R-HSA-5673001
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 signaling R-HSA-9020702
Antigen processing-Cross presentation R-HSA-1236975
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RUNX2 expression and activity R-HSA-8939902
Programmed Cell Death R-HSA-5357801
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'on' state R-HSA-5632684
Metabolism of polyamines R-HSA-351202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Ub-specific processing proteases R-HSA-5689880
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of proteins R-HSA-392499
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of RUNX3 expression and activity R-HSA-8941858
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S Transition R-HSA-69206
ABC transporter disorders R-HSA-5619084
Apoptosis R-HSA-109581
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RAS by GAPs R-HSA-5658442
DNA Replication R-HSA-69306
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of Apoptosis R-HSA-169911
Innate Immune System R-HSA-168249
Transport of small molecules R-HSA-382551
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by ROBO receptors R-HSA-376176
MAPK6/MAPK4 signaling R-HSA-5687128
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1/S DNA Damage Checkpoints R-HSA-69615
Downstream TCR signaling R-HSA-202424
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
Adaptive Immune System R-HSA-1280218
Metabolism of RNA R-HSA-8953854
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by Hedgehog R-HSA-5358351
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by NOTCH4 R-HSA-9013694
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of DVL R-HSA-4641258
Host Interactions of HIV factors R-HSA-162909
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Post-translational protein modification R-HSA-597592
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cytokine Signaling in Immune system R-HSA-1280215
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular response to hypoxia R-HSA-1234174
Asymmetric localization of PCP proteins R-HSA-4608870
TCR signaling R-HSA-202403
Signal Transduction R-HSA-162582
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Beta-catenin independent WNT signaling R-HSA-3858494
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Orc1 removal from chromatin R-HSA-68949
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX2 R-HSA-8878166
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
TCF dependent signaling in response to WNT R-HSA-201681
Nuclear events mediated by NFE2L2 R-HSA-9759194
Separation of Sister Chromatids R-HSA-2467813
Mitotic Anaphase R-HSA-68882
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism R-HSA-1430728
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by NOTCH R-HSA-157118
Infectious disease R-HSA-5663205
PCP/CE pathway R-HSA-4086400
Metabolism of amino acids and derivatives R-HSA-71291
PTEN Regulation R-HSA-6807070
Degradation of GLI2 by the proteasome R-HSA-5610783
Axon guidance R-HSA-422475
ABC-family proteins mediated transport R-HSA-382556
FCERI mediated NF-kB activation R-HSA-2871837
NIK-->noncanonical NF-kB signaling R-HSA-5676590
HIV Infection R-HSA-162906
Nervous system development R-HSA-9675108
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle Checkpoints R-HSA-69620
Hh mutants are degraded by ERAD R-HSA-5362768
Apoptosis R-HSA-109581
Asymmetric localization of PCP proteins R-HSA-4608870
M Phase R-HSA-68886
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle R-HSA-1640170
Hedgehog 'off' state R-HSA-5610787
Gene expression (Transcription) R-HSA-74160
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Axon guidance R-HSA-422475
Mitotic Anaphase R-HSA-68882
Metabolism of polyamines R-HSA-351202
DNA Replication Pre-Initiation R-HSA-69002
Defective CFTR causes cystic fibrosis R-HSA-5678895
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream TCR signaling R-HSA-202424
Signaling by WNT R-HSA-195721
Neddylation R-HSA-8951664
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle Checkpoints R-HSA-69620
Hh mutants abrogate ligand secretion R-HSA-5387390
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of RNA R-HSA-8953854
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Negative regulation of NOTCH4 signaling R-HSA-9604323
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
Orc1 removal from chromatin R-HSA-68949
Regulation of Apoptosis R-HSA-169911
S Phase R-HSA-69242
Hedgehog 'on' state R-HSA-5632684
Metabolism of amino acids and derivatives R-HSA-71291
Stabilization of p53 R-HSA-69541
ER-Phagosome pathway R-HSA-1236974
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RNA Polymerase II Transcription R-HSA-73857
Metabolism R-HSA-1430728
Mitotic G2-G2/M phases R-HSA-453274
Interleukin-1 signaling R-HSA-9020702
HIV Infection R-HSA-162906
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Programmed Cell Death R-HSA-5357801
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Developmental Biology R-HSA-1266738
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
Ub-specific processing proteases R-HSA-5689880
Cell Cycle, Mitotic R-HSA-69278
G2/M Transition R-HSA-69275
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by ROBO receptors R-HSA-376176
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 family signaling R-HSA-446652
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular responses to stimuli R-HSA-8953897
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transcriptional regulation by RUNX3 R-HSA-8878159
Antigen processing-Cross presentation R-HSA-1236975
PTEN Regulation R-HSA-6807070
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S Transition R-HSA-69206
Degradation of AXIN R-HSA-4641257
Nuclear events mediated by NFE2L2 R-HSA-9759194
UCH proteinases R-HSA-5689603
Metabolism of proteins R-HSA-392499
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI1 by the proteasome R-HSA-5610780
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of RUNX3 expression and activity R-HSA-8941858
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK family signaling cascades R-HSA-5683057
Synthesis of DNA R-HSA-69239
Host Interactions of HIV factors R-HSA-162909
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Switching of origins to a post-replicative state R-HSA-69052
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Disease R-HSA-1643685
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog ligand biogenesis R-HSA-5358346
Infectious disease R-HSA-5663205
CLEC7A (Dectin-1) signaling R-HSA-5607764
G2/M Checkpoints R-HSA-69481
Cellular responses to stress R-HSA-2262752
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
FCERI mediated NF-kB activation R-HSA-2871837
ABC-family proteins mediated transport R-HSA-382556
PCP/CE pathway R-HSA-4086400
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of beta-catenin by the destruction complex R-HSA-195253
Deubiquitination R-HSA-5688426
Immune System R-HSA-168256
Cyclin E associated events during G1/S transition R-HSA-69202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by NOTCH4 R-HSA-9013694
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Signaling by Hedgehog R-HSA-5358351
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Nervous system development R-HSA-9675108
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic G1 phase and G1/S transition R-HSA-453279
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Intracellular signaling by second messengers R-HSA-9006925
Cellular response to chemical stress R-HSA-9711123
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transport of small molecules R-HSA-382551
Separation of Sister Chromatids R-HSA-2467813
Signaling by NOTCH R-HSA-157118
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S DNA Damage Checkpoints R-HSA-69615
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Neutrophil degranulation R-HSA-6798695
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
TCR signaling R-HSA-202403
p53-Independent DNA Damage Response R-HSA-69610
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Activation of NF-kappaB in B cells R-HSA-1169091
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Innate Immune System R-HSA-168249
Post-translational protein modification R-HSA-597592
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
G2/M Checkpoints R-HSA-69481
ER-Phagosome pathway R-HSA-1236974
Assembly of the pre-replicative complex R-HSA-68867
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Adaptive Immune System R-HSA-1280218
Neutrophil degranulation R-HSA-6798695
Cellular response to chemical stress R-HSA-9711123
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCR signaling R-HSA-202403
Deubiquitination R-HSA-5688426
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
p53-Independent DNA Damage Response R-HSA-69610
Host Interactions of HIV factors R-HSA-162909
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic G1 phase and G1/S transition R-HSA-453279
Stabilization of p53 R-HSA-69541
Degradation of GLI2 by the proteasome R-HSA-5610783
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'off' state R-HSA-5610787
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Negative regulation of NOTCH4 signaling R-HSA-9604323
Generic Transcription Pathway R-HSA-212436
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by Hedgehog R-HSA-5358351
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Degradation of AXIN R-HSA-4641257
MAPK family signaling cascades R-HSA-5683057
Degradation of DVL R-HSA-4641258
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Switching of origins to a post-replicative state R-HSA-69052
Regulation of RUNX2 expression and activity R-HSA-8939902
FCERI mediated NF-kB activation R-HSA-2871837
Orc1 removal from chromatin R-HSA-68949
C-type lectin receptors (CLRs) R-HSA-5621481
Gene expression (Transcription) R-HSA-74160
Hh mutants are degraded by ERAD R-HSA-5362768
Transport of small molecules R-HSA-382551
MAPK1/MAPK3 signaling R-HSA-5684996
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cellular responses to stimuli R-HSA-8953897
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
Activation of NF-kappaB in B cells R-HSA-1169091
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Transcriptional regulation by RUNX1 R-HSA-8878171
Infectious disease R-HSA-5663205
Metabolism of polyamines R-HSA-351202
Interleukin-1 signaling R-HSA-9020702
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
Innate Immune System R-HSA-168249
Post-translational protein modification R-HSA-597592
G2/M Transition R-HSA-69275
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
DNA Replication R-HSA-69306
Regulation of RAS by GAPs R-HSA-5658442
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RAF/MAP kinase cascade R-HSA-5673001
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
HIV Infection R-HSA-162906
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Replication Pre-Initiation R-HSA-69002
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog ligand biogenesis R-HSA-5358346
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of PTEN stability and activity R-HSA-8948751
Neddylation R-HSA-8951664
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of RUNX3 expression and activity R-HSA-8941858
ABC transporter disorders R-HSA-5619084
Nervous system development R-HSA-9675108
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle Checkpoints R-HSA-69620
Apoptosis R-HSA-109581
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 family signaling R-HSA-446652
Synthesis of DNA R-HSA-69239
Cellular responses to stress R-HSA-2262752
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Nuclear events mediated by NFE2L2 R-HSA-9759194
RNA Polymerase II Transcription R-HSA-73857
Class I MHC mediated antigen processing & presentation R-HSA-983169
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX3 R-HSA-8878159
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
KEAP1-NFE2L2 pathway R-HSA-9755511
UCH proteinases R-HSA-5689603
Signaling by WNT R-HSA-195721
Mitotic Metaphase and Anaphase R-HSA-2555396
Immune System R-HSA-168256
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Downstream TCR signaling R-HSA-202424
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of mitotic cell cycle R-HSA-453276
Degradation of beta-catenin by the destruction complex R-HSA-195253
Antigen processing-Cross presentation R-HSA-1236975
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of GLI1 by the proteasome R-HSA-5610780
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism R-HSA-1430728
Separation of Sister Chromatids R-HSA-2467813
ABC-family proteins mediated transport R-HSA-382556
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hedgehog 'on' state R-HSA-5632684
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
Metabolism of RNA R-HSA-8953854
G1/S Transition R-HSA-69206
Disorders of transmembrane transporters R-HSA-5619115
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cell Cycle R-HSA-1640170
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of Apoptosis R-HSA-169911
Programmed Cell Death R-HSA-5357801
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PIP3 activates AKT signaling R-HSA-1257604
S Phase R-HSA-69242
Signaling by Interleukins R-HSA-449147
Signaling by Interleukins R-HSA-449147
p53-Dependent G1 DNA Damage Response R-HSA-69563
Immune System R-HSA-168256
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'off' state R-HSA-5610787
DNA Replication R-HSA-69306
G2/M Checkpoints R-HSA-69481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of GLI1 by the proteasome R-HSA-5610780
PTEN Regulation R-HSA-6807070
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by WNT R-HSA-195721
Regulation of RUNX3 expression and activity R-HSA-8941858
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Intracellular signaling by second messengers R-HSA-9006925
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular response to chemical stress R-HSA-9711123
CLEC7A (Dectin-1) signaling R-HSA-5607764
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic G2-G2/M phases R-HSA-453274
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
Metabolism of RNA R-HSA-8953854
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
UCH proteinases R-HSA-5689603
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by ROBO receptors R-HSA-376176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cytokine Signaling in Immune system R-HSA-1280215
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hh mutants are degraded by ERAD R-HSA-5362768
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular responses to stress R-HSA-2262752
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog ligand biogenesis R-HSA-5358346
Nervous system development R-HSA-9675108
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Interleukin-1 signaling R-HSA-9020702
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 family signaling R-HSA-446652
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of polyamines R-HSA-351202
Axon guidance R-HSA-422475
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ub-specific processing proteases R-HSA-5689880
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to hypoxia R-HSA-1234174
Programmed Cell Death R-HSA-5357801
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signal Transduction R-HSA-162582
Cell Cycle R-HSA-1640170
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle Checkpoints R-HSA-69620
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of PTEN stability and activity R-HSA-8948751
Infectious disease R-HSA-5663205
Metabolism of amino acids and derivatives R-HSA-71291
Negative regulation of NOTCH4 signaling R-HSA-9604323
Vpu mediated degradation of CD4 R-HSA-180534
Disease R-HSA-1643685
Signaling by Hedgehog R-HSA-5358351
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
DNA Replication Pre-Initiation R-HSA-69002
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of NF-kappaB in B cells R-HSA-1169091
S Phase R-HSA-69242
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of mitotic cell cycle R-HSA-453276
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
Degradation of AXIN R-HSA-4641257
Synthesis of DNA R-HSA-69239
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of expression of SLITs and ROBOs R-HSA-9010553
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ABC-family proteins mediated transport R-HSA-382556
G1/S Transition R-HSA-69206
Apoptosis R-HSA-109581
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M Transition R-HSA-69275
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Neutrophil degranulation R-HSA-6798695
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of Apoptosis R-HSA-169911
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Stabilization of p53 R-HSA-69541
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH4 R-HSA-9013694
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCF dependent signaling in response to WNT R-HSA-201681
Disorders of transmembrane transporters R-HSA-5619115
Innate Immune System R-HSA-168249
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
Deubiquitination R-HSA-5688426
HIV Infection R-HSA-162906
Switching of origins to a post-replicative state R-HSA-69052
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stimuli R-HSA-8953897
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream TCR signaling R-HSA-202424
Transport of small molecules R-HSA-382551
Assembly of the pre-replicative complex R-HSA-68867
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of proteins R-HSA-392499
Hedgehog 'on' state R-HSA-5632684
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX2 expression and activity R-HSA-8939902
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX2 R-HSA-8878166
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ER-Phagosome pathway R-HSA-1236974
M Phase R-HSA-68886
TCR signaling R-HSA-202403
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Independent DNA Damage Response R-HSA-69610
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of beta-catenin by the destruction complex R-HSA-195253
Host Interactions of HIV factors R-HSA-162909
Post-translational protein modification R-HSA-597592
Mitotic Anaphase R-HSA-68882
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle, Mitotic R-HSA-69278
KEAP1-NFE2L2 pathway R-HSA-9755511
Separation of Sister Chromatids R-HSA-2467813
C-type lectin receptors (CLRs) R-HSA-5621481
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Vif-mediated degradation of APOBEC3G R-HSA-180585
Deubiquitination R-HSA-5688426
G2/M Checkpoints R-HSA-69481
Cellular responses to stimuli R-HSA-8953897
Degradation of DVL R-HSA-4641258
ABC transporter disorders R-HSA-5619084
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by Interleukins R-HSA-449147
MAPK6/MAPK4 signaling R-HSA-5687128
Cyclin E associated events during G1/S transition R-HSA-69202
Hh mutants abrogate ligand secretion R-HSA-5387390
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vif-mediated degradation of APOBEC3G R-HSA-180585
DNA Replication R-HSA-69306
RAF/MAP kinase cascade R-HSA-5673001
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nervous system development R-HSA-9675108
Regulation of RUNX2 expression and activity R-HSA-8939902
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Adaptive Immune System R-HSA-1280218
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of polyamines R-HSA-351202
Host Interactions of HIV factors R-HSA-162909
Degradation of AXIN R-HSA-4641257
Disease R-HSA-1643685
CLEC7A (Dectin-1) signaling R-HSA-5607764
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Assembly of the pre-replicative complex R-HSA-68867
Mitotic G2-G2/M phases R-HSA-453274
Signal Transduction R-HSA-162582
TCF dependent signaling in response to WNT R-HSA-201681
Post-translational protein modification R-HSA-597592
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
UCH proteinases R-HSA-5689603
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Gene expression (Transcription) R-HSA-74160
Mitotic Metaphase and Anaphase R-HSA-2555396
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
Switching of origins to a post-replicative state R-HSA-69052
ABC-family proteins mediated transport R-HSA-382556
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RNA Polymerase II Transcription R-HSA-73857
Signaling by ROBO receptors R-HSA-376176
Transport of small molecules R-HSA-382551
Signaling by NOTCH4 R-HSA-9013694
Hedgehog ligand biogenesis R-HSA-5358346
DNA Replication Pre-Initiation R-HSA-69002
p53-Independent DNA Damage Response R-HSA-69610
ER-Phagosome pathway R-HSA-1236974
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by NOTCH R-HSA-157118
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G1 phase and G1/S transition R-HSA-453279
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of Apoptosis R-HSA-169911
Generic Transcription Pathway R-HSA-212436
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cell Cycle, Mitotic R-HSA-69278
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX3 R-HSA-8878159
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle R-HSA-1640170
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular response to chemical stress R-HSA-9711123
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Stabilization of p53 R-HSA-69541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of PTEN stability and activity R-HSA-8948751
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of RAS by GAPs R-HSA-5658442
PCP/CE pathway R-HSA-4086400
Ub-specific processing proteases R-HSA-5689880
Neutrophil degranulation R-HSA-6798695
Metabolism R-HSA-1430728
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Developmental Biology R-HSA-1266738
Beta-catenin independent WNT signaling R-HSA-3858494
Programmed Cell Death R-HSA-5357801
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disorders of transmembrane transporters R-HSA-5619115
Vpu mediated degradation of CD4 R-HSA-180534
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Separation of Sister Chromatids R-HSA-2467813
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TCR signaling R-HSA-202403
G1/S Transition R-HSA-69206
Apoptosis R-HSA-109581
Interleukin-1 family signaling R-HSA-446652
Hh mutants are degraded by ERAD R-HSA-5362768
Cell Cycle Checkpoints R-HSA-69620
Metabolism of RNA R-HSA-8953854
G2/M Transition R-HSA-69275
Cellular response to hypoxia R-HSA-1234174
Defective CFTR causes cystic fibrosis R-HSA-5678895
Interleukin-1 signaling R-HSA-9020702
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Negative regulation of NOTCH4 signaling R-HSA-9604323
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mitotic cell cycle R-HSA-453276
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
FCERI mediated NF-kB activation R-HSA-2871837
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cytokine Signaling in Immune system R-HSA-1280215
Hedgehog 'on' state R-HSA-5632684
Immune System R-HSA-168256
Signaling by Hedgehog R-HSA-5358351
PIP3 activates AKT signaling R-HSA-1257604
Axon guidance R-HSA-422475
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream TCR signaling R-HSA-202424
Asymmetric localization of PCP proteins R-HSA-4608870
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
HIV Infection R-HSA-162906
Synthesis of DNA R-HSA-69239
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Infectious disease R-HSA-5663205
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by the B Cell Receptor (BCR) R-HSA-983705
KEAP1-NFE2L2 pathway R-HSA-9755511
Innate Immune System R-HSA-168249
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of DVL R-HSA-4641258
Hedgehog 'on' state R-HSA-5632684
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disorders of transmembrane transporters R-HSA-5619115
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK6/MAPK4 signaling R-HSA-5687128
Innate Immune System R-HSA-168249
Ub-specific processing proteases R-HSA-5689880
Cell Cycle, Mitotic R-HSA-69278
Antigen processing-Cross presentation R-HSA-1236975
Host Interactions of HIV factors R-HSA-162909
ER-Phagosome pathway R-HSA-1236974
Cell Cycle Checkpoints R-HSA-69620
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Separation of Sister Chromatids R-HSA-2467813
Interleukin-1 signaling R-HSA-9020702
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular responses to stress R-HSA-2262752
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Gene expression (Transcription) R-HSA-74160
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of RNA R-HSA-8953854
G1/S Transition R-HSA-69206
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
PCP/CE pathway R-HSA-4086400
Cyclin E associated events during G1/S transition R-HSA-69202
Synthesis of DNA R-HSA-69239
p53-Independent DNA Damage Response R-HSA-69610
Regulation of Apoptosis R-HSA-169911
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to chemical stress R-HSA-9711123
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Post-translational protein modification R-HSA-597592
Intracellular signaling by second messengers R-HSA-9006925
Switching of origins to a post-replicative state R-HSA-69052
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Developmental Biology R-HSA-1266738
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle R-HSA-1640170
Nervous system development R-HSA-9675108
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Transition R-HSA-69275
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
MAPK1/MAPK3 signaling R-HSA-5684996
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog 'off' state R-HSA-5610787
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hh mutants are degraded by ERAD R-HSA-5362768
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of PTEN stability and activity R-HSA-8948751
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCF dependent signaling in response to WNT R-HSA-201681
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
DNA Replication Pre-Initiation R-HSA-69002
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK family signaling cascades R-HSA-5683057
Asymmetric localization of PCP proteins R-HSA-4608870
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of RUNX3 expression and activity R-HSA-8941858
Activation of NF-kappaB in B cells R-HSA-1169091
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of polyamines R-HSA-351202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
Neutrophil degranulation R-HSA-6798695
Degradation of GLI2 by the proteasome R-HSA-5610783
S Phase R-HSA-69242
Signaling by WNT R-HSA-195721
Signaling by NOTCH R-HSA-157118
Cellular responses to stimuli R-HSA-8953897
p53-Dependent G1 DNA Damage Response R-HSA-69563
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of AXIN R-HSA-4641257
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RAS by GAPs R-HSA-5658442
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of RUNX2 expression and activity R-HSA-8939902
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism R-HSA-1430728
Adaptive Immune System R-HSA-1280218
HIV Infection R-HSA-162906
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
Mitotic Metaphase and Anaphase R-HSA-2555396
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by Hedgehog R-HSA-5358351
FCERI mediated NF-kB activation R-HSA-2871837
Negative regulation of NOTCH4 signaling R-HSA-9604323
Deubiquitination R-HSA-5688426
Neddylation R-HSA-8951664
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream TCR signaling R-HSA-202424
Cellular response to hypoxia R-HSA-1234174
Programmed Cell Death R-HSA-5357801
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vpu mediated degradation of CD4 R-HSA-180534
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
G2/M Checkpoints R-HSA-69481
Signaling by ROBO receptors R-HSA-376176
TCR signaling R-HSA-202403
Mitotic Anaphase R-HSA-68882
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transport of small molecules R-HSA-382551
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hh mutants abrogate ligand secretion R-HSA-5387390
Apoptosis R-HSA-109581
Degradation of GLI1 by the proteasome R-HSA-5610780
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mitotic cell cycle R-HSA-453276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH4 R-HSA-9013694
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of proteins R-HSA-392499
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ABC transporter disorders R-HSA-5619084
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
KEAP1-NFE2L2 pathway R-HSA-9755511
ABC-family proteins mediated transport R-HSA-382556
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
ER-Phagosome pathway R-HSA-1236974
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by NOTCH R-HSA-157118
UCH proteinases R-HSA-5689603
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Innate Immune System R-HSA-168249
Cellular responses to stimuli R-HSA-8953897
Mitotic G2-G2/M phases R-HSA-453274
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RUNX2 expression and activity R-HSA-8939902
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of RNA R-HSA-8953854
Signaling by ROBO receptors R-HSA-376176
Hh mutants abrogate ligand secretion R-HSA-5387390
Hedgehog 'off' state R-HSA-5610787
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Axon guidance R-HSA-422475
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Stabilization of p53 R-HSA-69541
CLEC7A (Dectin-1) signaling R-HSA-5607764
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 family signaling R-HSA-446652
Switching of origins to a post-replicative state R-HSA-69052
Transport of small molecules R-HSA-382551
Ub-specific processing proteases R-HSA-5689880
HIV Infection R-HSA-162906
Neddylation R-HSA-8951664
Degradation of beta-catenin by the destruction complex R-HSA-195253
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle, Mitotic R-HSA-69278
Synthesis of DNA R-HSA-69239
Apoptosis R-HSA-109581
Signaling by NOTCH4 R-HSA-9013694
NIK-->noncanonical NF-kB signaling R-HSA-5676590
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hedgehog 'on' state R-HSA-5632684
Generic Transcription Pathway R-HSA-212436
G1/S DNA Damage Checkpoints R-HSA-69615
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
M Phase R-HSA-68886
Separation of Sister Chromatids R-HSA-2467813
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stress R-HSA-2262752
Intracellular signaling by second messengers R-HSA-9006925
Disorders of transmembrane transporters R-HSA-5619115
Mitotic Anaphase R-HSA-68882
S Phase R-HSA-69242
Cellular response to chemical stress R-HSA-9711123
Adaptive Immune System R-HSA-1280218
Host Interactions of HIV factors R-HSA-162909
Asymmetric localization of PCP proteins R-HSA-4608870
Disease R-HSA-1643685
Regulation of PTEN stability and activity R-HSA-8948751
Defective CFTR causes cystic fibrosis R-HSA-5678895
RNA Polymerase II Transcription R-HSA-73857
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism R-HSA-1430728
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent DNA Damage Response R-HSA-69610
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S Transition R-HSA-69206
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Developmental Biology R-HSA-1266738
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by WNT R-HSA-195721
PTEN Regulation R-HSA-6807070
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of proteins R-HSA-392499
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Vpu mediated degradation of CD4 R-HSA-180534
Neutrophil degranulation R-HSA-6798695
Assembly of the pre-replicative complex R-HSA-68867
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Checkpoints R-HSA-69481
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Deubiquitination R-HSA-5688426
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
DNA Replication R-HSA-69306
Degradation of DVL R-HSA-4641258
Downstream TCR signaling R-HSA-202424
ABC-family proteins mediated transport R-HSA-382556
Hedgehog ligand biogenesis R-HSA-5358346
Antigen processing-Cross presentation R-HSA-1236975
Degradation of GLI2 by the proteasome R-HSA-5610783
Gene expression (Transcription) R-HSA-74160
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vif-mediated degradation of APOBEC3G R-HSA-180585
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic Metaphase and Anaphase R-HSA-2555396
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX1 R-HSA-8878171
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of polyamines R-HSA-351202
Signaling by Interleukins R-HSA-449147
Regulation of mitotic cell cycle R-HSA-453276
Class I MHC mediated antigen processing & presentation R-HSA-983169
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK family signaling cascades R-HSA-5683057
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
RAF/MAP kinase cascade R-HSA-5673001
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of AXIN R-HSA-4641257
Cyclin E associated events during G1/S transition R-HSA-69202
PCP/CE pathway R-HSA-4086400
Signaling by Hedgehog R-HSA-5358351
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ABC transporter disorders R-HSA-5619084
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of Apoptosis R-HSA-169911

Expression Atlas ENSG00000185627
NCBI gene (formerly Entrezgene) 5719
GeneCards 9558
HGNC Symbol HGNC:9558
MIM gene 603481
UniProtKB Gene Name Q9UNM6
WikiGene 5719
Gene: PSMC6
Ensembl ID : ENSG00000100519
Description: proteasome 26S subunit, ATPase 6
Gene Synonyms: P42,RPT5
5 APIs:
229 Possible Orthologues:

DNA Replication R-HSA-69306
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
HIV Infection R-HSA-162906
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 family signaling R-HSA-446652
Assembly of the pre-replicative complex R-HSA-68867
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Generic Transcription Pathway R-HSA-212436
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by NOTCH4 R-HSA-9013694
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Anaphase R-HSA-68882
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
PCP/CE pathway R-HSA-4086400
Signaling by Interleukins R-HSA-449147
Beta-catenin independent WNT signaling R-HSA-3858494
C-type lectin receptors (CLRs) R-HSA-5621481
Infectious disease R-HSA-5663205
SARS-CoV-1 Infection R-HSA-9678108
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G2-G2/M phases R-HSA-453274
HIV Infection R-HSA-162906
p53-Independent DNA Damage Response R-HSA-69610
Signal Transduction R-HSA-162582
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Separation of Sister Chromatids R-HSA-2467813
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of GLI2 by the proteasome R-HSA-5610783
Stabilization of p53 R-HSA-69541
Transport of small molecules R-HSA-382551
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle Checkpoints R-HSA-69620
S Phase R-HSA-69242
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
Disorders of transmembrane transporters R-HSA-5619115
CLEC7A (Dectin-1) signaling R-HSA-5607764
Downstream TCR signaling R-HSA-202424
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
Vpu mediated degradation of CD4 R-HSA-180534
Activation of NF-kappaB in B cells R-HSA-1169091
Nuclear events mediated by NFE2L2 R-HSA-9759194
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hedgehog 'off' state R-HSA-5610787
Signaling by ROBO receptors R-HSA-376176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX3 R-HSA-8878159
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RNA Polymerase II Transcription R-HSA-73857
Neddylation R-HSA-8951664
Disease R-HSA-1643685
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
UCH proteinases R-HSA-5689603
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RAS by GAPs R-HSA-5658442
Axon guidance R-HSA-422475
Adaptive Immune System R-HSA-1280218
Deubiquitination R-HSA-5688426
Synthesis of DNA R-HSA-69239
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G2/M Checkpoints R-HSA-69481
ABC-family proteins mediated transport R-HSA-382556
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Hedgehog ligand biogenesis R-HSA-5358346
Nervous system development R-HSA-9675108
Regulation of PTEN stability and activity R-HSA-8948751
Innate Immune System R-HSA-168249
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism R-HSA-1430728
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cytokine Signaling in Immune system R-HSA-1280215
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of polyamines R-HSA-351202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK family signaling cascades R-HSA-5683057
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to chemical stress R-HSA-9711123
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stress R-HSA-2262752
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX2 R-HSA-8878166
Class I MHC mediated antigen processing & presentation R-HSA-983169
Programmed Cell Death R-HSA-5357801
Host Interactions of HIV factors R-HSA-162909
Hedgehog 'on' state R-HSA-5632684
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular responses to stimuli R-HSA-8953897
Cellular response to hypoxia R-HSA-1234174
ER-Phagosome pathway R-HSA-1236974
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PTEN Regulation R-HSA-6807070
MAPK1/MAPK3 signaling R-HSA-5684996
Immune System R-HSA-168256
SARS-CoV-1-host interactions R-HSA-9692914
G2/M Transition R-HSA-69275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
Orc1 removal from chromatin R-HSA-68949
Intracellular signaling by second messengers R-HSA-9006925
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of DVL R-HSA-4641258
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCR signaling R-HSA-202403
ABC transporter disorders R-HSA-5619084
Developmental Biology R-HSA-1266738
SARS-CoV Infections R-HSA-9679506
G1/S Transition R-HSA-69206
Apoptosis R-HSA-109581
Signaling by NOTCH R-HSA-157118
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
Hh mutants abrogate ligand secretion R-HSA-5387390
Ub-specific processing proteases R-HSA-5689880
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
DNA Replication Pre-Initiation R-HSA-69002
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of Apoptosis R-HSA-169911
Post-translational protein modification R-HSA-597592
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of AXIN R-HSA-4641257
Regulation of expression of SLITs and ROBOs R-HSA-9010553
S Phase R-HSA-69242
p53-Independent DNA Damage Response R-HSA-69610
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Transport of small molecules R-HSA-382551
Mitotic Metaphase and Anaphase R-HSA-2555396
M Phase R-HSA-68886
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle R-HSA-1640170
Metabolism of polyamines R-HSA-351202
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by WNT R-HSA-195721
Metabolism of RNA R-HSA-8953854
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Vpu mediated degradation of CD4 R-HSA-180534
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
Cyclin E associated events during G1/S transition R-HSA-69202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog ligand biogenesis R-HSA-5358346
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403
Hedgehog 'off' state R-HSA-5610787
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disorders of transmembrane transporters R-HSA-5619115
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neddylation R-HSA-8951664
SARS-CoV-1-host interactions R-HSA-9692914
UCH proteinases R-HSA-5689603
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of Apoptosis R-HSA-169911
Regulation of PTEN stability and activity R-HSA-8948751
Synthesis of DNA R-HSA-69239
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stress R-HSA-2262752
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Intracellular signaling by second messengers R-HSA-9006925
G2/M Transition R-HSA-69275
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Degradation of AXIN R-HSA-4641257
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of amino acids and derivatives R-HSA-71291
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants are degraded by ERAD R-HSA-5362768
Developmental Biology R-HSA-1266738
Post-translational protein modification R-HSA-597592
Separation of Sister Chromatids R-HSA-2467813
MAPK family signaling cascades R-HSA-5683057
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Negative regulation of NOTCH4 signaling R-HSA-9604323
ER-Phagosome pathway R-HSA-1236974
G2/M Checkpoints R-HSA-69481
Degradation of GLI1 by the proteasome R-HSA-5610780
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism R-HSA-1430728
Degradation of DVL R-HSA-4641258
ABC-family proteins mediated transport R-HSA-382556
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by ROBO receptors R-HSA-376176
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 signaling R-HSA-9020702
Signaling by Interleukins R-HSA-449147
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RAS by GAPs R-HSA-5658442
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream TCR signaling R-HSA-202424
Axon guidance R-HSA-422475
Cellular response to hypoxia R-HSA-1234174
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stimuli R-HSA-8953897
Disease R-HSA-1643685
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1 DNA Damage Response R-HSA-69563
SARS-CoV Infections R-HSA-9679506
SARS-CoV-1 Infection R-HSA-9678108
HIV Infection R-HSA-162906
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle, Mitotic R-HSA-69278
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PCP/CE pathway R-HSA-4086400
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle Checkpoints R-HSA-69620
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G2-G2/M phases R-HSA-453274
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants abrogate ligand secretion R-HSA-5387390
Apoptosis R-HSA-109581
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
NIK-->noncanonical NF-kB signaling R-HSA-5676590
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Beta-catenin independent WNT signaling R-HSA-3858494
DNA Replication Pre-Initiation R-HSA-69002
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Deubiquitination R-HSA-5688426
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Antigen processing-Cross presentation R-HSA-1236975
DNA Replication R-HSA-69306
S Phase R-HSA-69242
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
TCR signaling R-HSA-202403
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants are degraded by ERAD R-HSA-5362768
PTEN Regulation R-HSA-6807070
FCERI mediated NF-kB activation R-HSA-2871837
Neddylation R-HSA-8951664
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by Interleukins R-HSA-449147
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Assembly of the pre-replicative complex R-HSA-68867
Metabolism R-HSA-1430728
Separation of Sister Chromatids R-HSA-2467813
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Adaptive Immune System R-HSA-1280218
Metabolism of polyamines R-HSA-351202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle, Mitotic R-HSA-69278
ER-Phagosome pathway R-HSA-1236974
Vpu mediated degradation of CD4 R-HSA-180534
Axon guidance R-HSA-422475
Cellular responses to stress R-HSA-2262752
SARS-CoV-1-host interactions R-HSA-9692914
Interleukin-1 signaling R-HSA-9020702
Regulation of RUNX2 expression and activity R-HSA-8939902
Vif-mediated degradation of APOBEC3G R-HSA-180585
Innate Immune System R-HSA-168249
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
Mitotic G2-G2/M phases R-HSA-453274
p53-Independent DNA Damage Response R-HSA-69610
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
SARS-CoV-1 Infection R-HSA-9678108
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI1 by the proteasome R-HSA-5610780
UCH proteinases R-HSA-5689603
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'off' state R-HSA-5610787
G1/S Transition R-HSA-69206
Infectious disease R-HSA-5663205
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of beta-catenin by the destruction complex R-HSA-195253
Developmental Biology R-HSA-1266738
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to hypoxia R-HSA-1234174
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SARS-CoV Infections R-HSA-9679506
Signaling by Hedgehog R-HSA-5358351
Asymmetric localization of PCP proteins R-HSA-4608870
Stabilization of p53 R-HSA-69541
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mitotic cell cycle R-HSA-453276
G1/S DNA Damage Checkpoints R-HSA-69615
ABC transporter disorders R-HSA-5619084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Defective CFTR causes cystic fibrosis R-HSA-5678895
Gene expression (Transcription) R-HSA-74160
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 family signaling R-HSA-446652
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Host Interactions of HIV factors R-HSA-162909
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transport of small molecules R-HSA-382551
Mitotic Anaphase R-HSA-68882
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by WNT R-HSA-195721
HIV Infection R-HSA-162906
Class I MHC mediated antigen processing & presentation R-HSA-983169
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Disorders of transmembrane transporters R-HSA-5619115
Ub-specific processing proteases R-HSA-5689880
Hh mutants abrogate ligand secretion R-HSA-5387390
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCF dependent signaling in response to WNT R-HSA-201681
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
DNA Replication Pre-Initiation R-HSA-69002
Regulation of PTEN stability and activity R-HSA-8948751
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by ROBO receptors R-HSA-376176
Antigen processing-Cross presentation R-HSA-1236975
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of RNA R-HSA-8953854
Post-translational protein modification R-HSA-597592
Hedgehog 'on' state R-HSA-5632684
Synthesis of DNA R-HSA-69239
Activation of NF-kappaB in B cells R-HSA-1169091
KEAP1-NFE2L2 pathway R-HSA-9755511
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
Metabolism of proteins R-HSA-392499
Degradation of DVL R-HSA-4641258
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream TCR signaling R-HSA-202424
Beta-catenin independent WNT signaling R-HSA-3858494
G2/M Transition R-HSA-69275
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RNA Polymerase II Transcription R-HSA-73857
G2/M Checkpoints R-HSA-69481
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH R-HSA-157118
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
Deubiquitination R-HSA-5688426
Generic Transcription Pathway R-HSA-212436
Degradation of AXIN R-HSA-4641257
PCP/CE pathway R-HSA-4086400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX3 R-HSA-8878159
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Programmed Cell Death R-HSA-5357801
Apoptosis R-HSA-109581
RAF/MAP kinase cascade R-HSA-5673001
CLEC7A (Dectin-1) signaling R-HSA-5607764
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G1 phase and G1/S transition R-HSA-453279
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular response to chemical stress R-HSA-9711123
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Cellular response to chemical stress R-HSA-9711123
Cell Cycle, Mitotic R-HSA-69278
Infectious disease R-HSA-5663205
ER-Phagosome pathway R-HSA-1236974
Separation of Sister Chromatids R-HSA-2467813
Defective CFTR causes cystic fibrosis R-HSA-5678895
Gene expression (Transcription) R-HSA-74160
Mitotic Metaphase and Anaphase R-HSA-2555396
Post-translational protein modification R-HSA-597592
Degradation of AXIN R-HSA-4641257
Regulation of RAS by GAPs R-HSA-5658442
Orc1 removal from chromatin R-HSA-68949
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Dependent G1 DNA Damage Response R-HSA-69563
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Transition R-HSA-69275
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Vpu mediated degradation of CD4 R-HSA-180534
Adaptive Immune System R-HSA-1280218
Switching of origins to a post-replicative state R-HSA-69052
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
S Phase R-HSA-69242
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
DNA Replication R-HSA-69306
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of proteins R-HSA-392499
SARS-CoV-1 Infection R-HSA-9678108
Cellular responses to stimuli R-HSA-8953897
Signaling by NOTCH R-HSA-157118
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RAF/MAP kinase cascade R-HSA-5673001
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
MAPK6/MAPK4 signaling R-HSA-5687128
Synthesis of DNA R-HSA-69239
Cellular response to hypoxia R-HSA-1234174
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Downstream TCR signaling R-HSA-202424
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent DNA Damage Response R-HSA-69610
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle R-HSA-1640170
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication Pre-Initiation R-HSA-69002
Nuclear events mediated by NFE2L2 R-HSA-9759194
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Host Interactions of HIV factors R-HSA-162909
Disease R-HSA-1643685
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI1 by the proteasome R-HSA-5610780
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
TCR signaling R-HSA-202403
Interleukin-1 signaling R-HSA-9020702
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transport of small molecules R-HSA-382551
Ub-specific processing proteases R-HSA-5689880
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of Apoptosis R-HSA-169911
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
HIV Infection R-HSA-162906
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic Anaphase R-HSA-68882
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Developmental Biology R-HSA-1266738
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Generic Transcription Pathway R-HSA-212436
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
MAPK1/MAPK3 signaling R-HSA-5684996
Hh mutants are degraded by ERAD R-HSA-5362768
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
PTEN Regulation R-HSA-6807070
Signaling by Hedgehog R-HSA-5358351
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cyclin E associated events during G1/S transition R-HSA-69202
M Phase R-HSA-68886
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by NOTCH4 R-HSA-9013694
Hedgehog 'on' state R-HSA-5632684
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
Intracellular signaling by second messengers R-HSA-9006925
Neddylation R-HSA-8951664
Metabolism R-HSA-1430728
Disorders of transmembrane transporters R-HSA-5619115
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G2-G2/M phases R-HSA-453274
Stabilization of p53 R-HSA-69541
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
SARS-CoV Infections R-HSA-9679506
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hh mutants abrogate ligand secretion R-HSA-5387390
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
PCP/CE pathway R-HSA-4086400
G1/S Transition R-HSA-69206
Vif-mediated degradation of APOBEC3G R-HSA-180585
Apoptosis R-HSA-109581
Negative regulation of NOTCH4 signaling R-HSA-9604323
SARS-CoV-1-host interactions R-HSA-9692914
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC-family proteins mediated transport R-HSA-382556
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle, Mitotic R-HSA-69278
Nervous system development R-HSA-9675108
MAPK family signaling cascades R-HSA-5683057
Degradation of AXIN R-HSA-4641257
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RUNX2 expression and activity R-HSA-8939902
Transport of small molecules R-HSA-382551
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX3 expression and activity R-HSA-8941858
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
Mitotic G2-G2/M phases R-HSA-453274
Cytokine Signaling in Immune system R-HSA-1280215
Deubiquitination R-HSA-5688426
Cell Cycle R-HSA-1640170
CLEC7A (Dectin-1) signaling R-HSA-5607764
Gene expression (Transcription) R-HSA-74160
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI2 by the proteasome R-HSA-5610783
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Interleukin-1 family signaling R-HSA-446652
Beta-catenin independent WNT signaling R-HSA-3858494
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of amino acids and derivatives R-HSA-71291
Switching of origins to a post-replicative state R-HSA-69052
Host Interactions of HIV factors R-HSA-162909
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCR signaling R-HSA-202403
UCH proteinases R-HSA-5689603
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
Infectious disease R-HSA-5663205
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stress R-HSA-2262752
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of PTEN stability and activity R-HSA-8948751
RAF/MAP kinase cascade R-HSA-5673001
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to hypoxia R-HSA-1234174
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream TCR signaling R-HSA-202424
PCP/CE pathway R-HSA-4086400
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Dependent G1 DNA Damage Response R-HSA-69563
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX3 R-HSA-8878159
Orc1 removal from chromatin R-HSA-68949
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
Metabolism of proteins R-HSA-392499
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of DVL R-HSA-4641258
Signaling by ROBO receptors R-HSA-376176
Regulation of mitotic cell cycle R-HSA-453276
C-type lectin receptors (CLRs) R-HSA-5621481
M Phase R-HSA-68886
Signaling by WNT R-HSA-195721
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of polyamines R-HSA-351202
Signaling by NOTCH R-HSA-157118
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hedgehog 'off' state R-HSA-5610787
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants are degraded by ERAD R-HSA-5362768
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
G1/S DNA Damage Checkpoints R-HSA-69615
RNA Polymerase II Transcription R-HSA-73857
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of RAS by GAPs R-HSA-5658442
TCF dependent signaling in response to WNT R-HSA-201681
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Interleukin-1 signaling R-HSA-9020702
Ub-specific processing proteases R-HSA-5689880
ABC transporter disorders R-HSA-5619084
Cellular response to chemical stress R-HSA-9711123
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stimuli R-HSA-8953897
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by NOTCH4 R-HSA-9013694
Developmental Biology R-HSA-1266738
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Class I MHC mediated antigen processing & presentation R-HSA-983169
G2/M Checkpoints R-HSA-69481
SARS-CoV-1 Infection R-HSA-9678108
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
FCERI mediated NF-kB activation R-HSA-2871837
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Disorders of transmembrane transporters R-HSA-5619115
SARS-CoV-1-host interactions R-HSA-9692914
DNA Replication R-HSA-69306
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G1/S Transition R-HSA-69206
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
Cell Cycle Checkpoints R-HSA-69620
Antigen processing-Cross presentation R-HSA-1236975
Adaptive Immune System R-HSA-1280218
HIV Infection R-HSA-162906
Asymmetric localization of PCP proteins R-HSA-4608870
Apoptosis R-HSA-109581
SARS-CoV Infections R-HSA-9679506
ER-Phagosome pathway R-HSA-1236974
Intracellular signaling by second messengers R-HSA-9006925
Programmed Cell Death R-HSA-5357801
PTEN Regulation R-HSA-6807070
Metabolism of RNA R-HSA-8953854
Assembly of the pre-replicative complex R-HSA-68867
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC-family proteins mediated transport R-HSA-382556
Synthesis of DNA R-HSA-69239
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Vpu mediated degradation of CD4 R-HSA-180534
Activation of NF-kappaB in B cells R-HSA-1169091
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cyclin E associated events during G1/S transition R-HSA-69202
Metabolism R-HSA-1430728
G1/S DNA Damage Checkpoints R-HSA-69615
Interleukin-1 signaling R-HSA-9020702
SARS-CoV-1-host interactions R-HSA-9692914
Regulation of mitotic cell cycle R-HSA-453276
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G1 phase and G1/S transition R-HSA-453279
Adaptive Immune System R-HSA-1280218
Metabolism of polyamines R-HSA-351202
Cell Cycle Checkpoints R-HSA-69620
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Neddylation R-HSA-8951664
Degradation of DVL R-HSA-4641258
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
RAF/MAP kinase cascade R-HSA-5673001
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transport of small molecules R-HSA-382551
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Intracellular signaling by second messengers R-HSA-9006925
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Orc1 removal from chromatin R-HSA-68949
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of RAS by GAPs R-HSA-5658442
Switching of origins to a post-replicative state R-HSA-69052
UCH proteinases R-HSA-5689603
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transcriptional regulation by RUNX1 R-HSA-8878171
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants abrogate ligand secretion R-HSA-5387390
TCF dependent signaling in response to WNT R-HSA-201681
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of proteins R-HSA-392499
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Class I MHC mediated antigen processing & presentation R-HSA-983169
KEAP1-NFE2L2 pathway R-HSA-9755511
Post-translational protein modification R-HSA-597592
M Phase R-HSA-68886
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
MAPK6/MAPK4 signaling R-HSA-5687128
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK family signaling cascades R-HSA-5683057
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of RNA R-HSA-8953854
Antigen processing-Cross presentation R-HSA-1236975
Deubiquitination R-HSA-5688426
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
Infectious disease R-HSA-5663205
Vpu mediated degradation of CD4 R-HSA-180534
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signal Transduction R-HSA-162582
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of GLI2 by the proteasome R-HSA-5610783
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Interleukins R-HSA-449147
p53-Independent DNA Damage Response R-HSA-69610
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular responses to stimuli R-HSA-8953897
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
p53-Dependent G1 DNA Damage Response R-HSA-69563
Gene expression (Transcription) R-HSA-74160
DNA Replication R-HSA-69306
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to chemical stress R-HSA-9711123
Generic Transcription Pathway R-HSA-212436
Separation of Sister Chromatids R-HSA-2467813
Axon guidance R-HSA-422475
SARS-CoV-1 Infection R-HSA-9678108
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G2/M Checkpoints R-HSA-69481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cytokine Signaling in Immune system R-HSA-1280215
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog 'off' state R-HSA-5610787
Host Interactions of HIV factors R-HSA-162909
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic G2-G2/M phases R-HSA-453274
S Phase R-HSA-69242
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
Disorders of transmembrane transporters R-HSA-5619115
ABC transporter disorders R-HSA-5619084
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
DNA Replication Pre-Initiation R-HSA-69002
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic Metaphase and Anaphase R-HSA-2555396
Vif-mediated degradation of APOBEC3G R-HSA-180585
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stress R-HSA-2262752
Regulation of Apoptosis R-HSA-169911
Cellular response to hypoxia R-HSA-1234174
G1/S Transition R-HSA-69206
Stabilization of p53 R-HSA-69541
Signaling by NOTCH4 R-HSA-9013694
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PTEN Regulation R-HSA-6807070
Hedgehog ligand biogenesis R-HSA-5358346
ER-Phagosome pathway R-HSA-1236974
HIV Infection R-HSA-162906
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SARS-CoV Infections R-HSA-9679506
Degradation of AXIN R-HSA-4641257
Programmed Cell Death R-HSA-5357801
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Hedgehog R-HSA-5358351
Ub-specific processing proteases R-HSA-5689880
Synthesis of DNA R-HSA-69239
Asymmetric localization of PCP proteins R-HSA-4608870
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Interleukin-1 family signaling R-HSA-446652
Signaling by ROBO receptors R-HSA-376176
Hh mutants are degraded by ERAD R-HSA-5362768
TCR signaling R-HSA-202403
Signaling by NOTCH R-HSA-157118
RNA Polymerase II Transcription R-HSA-73857
Downstream TCR signaling R-HSA-202424
Hedgehog 'on' state R-HSA-5632684
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
KEAP1-NFE2L2 pathway R-HSA-9755511
Class I MHC mediated antigen processing & presentation R-HSA-983169
RNA Polymerase II Transcription R-HSA-73857
Regulation of Apoptosis R-HSA-169911
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Downstream TCR signaling R-HSA-202424
Vif-mediated degradation of APOBEC3G R-HSA-180585
Separation of Sister Chromatids R-HSA-2467813
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Negative regulation of NOTCH4 signaling R-HSA-9604323
Interleukin-1 family signaling R-HSA-446652
FCERI mediated NF-kB activation R-HSA-2871837
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of AXIN R-HSA-4641257
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic Metaphase and Anaphase R-HSA-2555396
SARS-CoV-1-host interactions R-HSA-9692914
Signaling by Hedgehog R-HSA-5358351
Transport of small molecules R-HSA-382551
Programmed Cell Death R-HSA-5357801
Degradation of GLI2 by the proteasome R-HSA-5610783
Host Interactions of HIV factors R-HSA-162909
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1 DNA Damage Response R-HSA-69563
UCH proteinases R-HSA-5689603
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hh mutants abrogate ligand secretion R-HSA-5387390
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to chemical stress R-HSA-9711123
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hh mutants are degraded by ERAD R-HSA-5362768
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Gene expression (Transcription) R-HSA-74160
RAF/MAP kinase cascade R-HSA-5673001
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
Developmental Biology R-HSA-1266738
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Synthesis of DNA R-HSA-69239
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Orc1 removal from chromatin R-HSA-68949
Signaling by ROBO receptors R-HSA-376176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'off' state R-HSA-5610787
Switching of origins to a post-replicative state R-HSA-69052
Axon guidance R-HSA-422475
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Antigen processing-Cross presentation R-HSA-1236975
C-type lectin receptors (CLRs) R-HSA-5621481
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721
MAPK1/MAPK3 signaling R-HSA-5684996
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Disease R-HSA-1643685
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of PTEN stability and activity R-HSA-8948751
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
PCP/CE pathway R-HSA-4086400
Signal Transduction R-HSA-162582
Interleukin-1 signaling R-HSA-9020702
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of beta-catenin by the destruction complex R-HSA-195253
Innate Immune System R-HSA-168249
Mitotic Anaphase R-HSA-68882
ABC transporter disorders R-HSA-5619084
p53-Independent DNA Damage Response R-HSA-69610
Assembly of the pre-replicative complex R-HSA-68867
Infectious disease R-HSA-5663205
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of polyamines R-HSA-351202
Defective CFTR causes cystic fibrosis R-HSA-5678895
G1/S DNA Damage Checkpoints R-HSA-69615
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular responses to stimuli R-HSA-8953897
Mitotic G2-G2/M phases R-HSA-453274
ABC-family proteins mediated transport R-HSA-382556
M Phase R-HSA-68886
MAPK6/MAPK4 signaling R-HSA-5687128
G2/M Checkpoints R-HSA-69481
DNA Replication R-HSA-69306
S Phase R-HSA-69242
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCR signaling R-HSA-202403
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
SARS-CoV Infections R-HSA-9679506
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH R-HSA-157118
SARS-CoV-1 Infection R-HSA-9678108
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Stabilization of p53 R-HSA-69541
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular response to hypoxia R-HSA-1234174
Ub-specific processing proteases R-HSA-5689880
Regulation of mitotic cell cycle R-HSA-453276
Regulation of RAS by GAPs R-HSA-5658442
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Apoptosis R-HSA-109581
Degradation of DVL R-HSA-4641258
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Asymmetric localization of PCP proteins R-HSA-4608870
CLEC7A (Dectin-1) signaling R-HSA-5607764
Neddylation R-HSA-8951664
Nervous system development R-HSA-9675108
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Post-translational protein modification R-HSA-597592
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stress R-HSA-2262752
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
PTEN Regulation R-HSA-6807070
Orc1 removal from chromatin R-HSA-68949
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of RNA R-HSA-8953854
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX3 expression and activity R-HSA-8941858
Cytokine Signaling in Immune system R-HSA-1280215
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TCR signaling R-HSA-202403
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'off' state R-HSA-5610787
Synthesis of DNA R-HSA-69239
Signaling by ROBO receptors R-HSA-376176
Downstream TCR signaling R-HSA-202424
S Phase R-HSA-69242
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
Disorders of transmembrane transporters R-HSA-5619115
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX3 R-HSA-8878159
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of Apoptosis R-HSA-169911
Beta-catenin independent WNT signaling R-HSA-3858494
Host Interactions of HIV factors R-HSA-162909
Separation of Sister Chromatids R-HSA-2467813
ER-Phagosome pathway R-HSA-1236974
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Regulation of RUNX2 expression and activity R-HSA-8939902
Signal Transduction R-HSA-162582
Regulation of mitotic cell cycle R-HSA-453276
Adaptive Immune System R-HSA-1280218
Nervous system development R-HSA-9675108
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SARS-CoV-1-host interactions R-HSA-9692914
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of proteins R-HSA-392499
Hedgehog ligand biogenesis R-HSA-5358346
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by WNT R-HSA-195721
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Programmed Cell Death R-HSA-5357801
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism R-HSA-1430728
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
G1/S Transition R-HSA-69206
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH R-HSA-157118
G2/M Checkpoints R-HSA-69481
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of AXIN R-HSA-4641257
RAF/MAP kinase cascade R-HSA-5673001
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of PTEN stability and activity R-HSA-8948751
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
Stabilization of p53 R-HSA-69541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PCP/CE pathway R-HSA-4086400
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 signaling R-HSA-9020702
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Assembly of the pre-replicative complex R-HSA-68867
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Anaphase R-HSA-68882
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle Checkpoints R-HSA-69620
Signaling by the B Cell Receptor (BCR) R-HSA-983705
MAPK family signaling cascades R-HSA-5683057
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to hypoxia R-HSA-1234174
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G1/S DNA Damage Checkpoints R-HSA-69615
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'on' state R-HSA-5632684
p53-Independent DNA Damage Response R-HSA-69610
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX2 R-HSA-8878166
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Axon guidance R-HSA-422475
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by NOTCH4 R-HSA-9013694
Cyclin E associated events during G1/S transition R-HSA-69202
Class I MHC mediated antigen processing & presentation R-HSA-983169
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Gene expression (Transcription) R-HSA-74160
Vif-mediated degradation of APOBEC3G R-HSA-180585
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Infectious disease R-HSA-5663205
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic G1 phase and G1/S transition R-HSA-453279
Transport of small molecules R-HSA-382551
Generic Transcription Pathway R-HSA-212436
Innate Immune System R-HSA-168249
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
Cell Cycle R-HSA-1640170
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Intracellular signaling by second messengers R-HSA-9006925
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
ABC transporter disorders R-HSA-5619084
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Hedgehog R-HSA-5358351
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of polyamines R-HSA-351202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Immune System R-HSA-168256
DNA Replication Pre-Initiation R-HSA-69002
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle, Mitotic R-HSA-69278
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Developmental Biology R-HSA-1266738
SARS-CoV-1 Infection R-HSA-9678108
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
Metabolism of RNA R-HSA-8953854
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stimuli R-HSA-8953897
Nervous system development R-HSA-9675108
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of mitotic cell cycle R-HSA-453276
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by ROBO receptors R-HSA-376176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Infectious disease R-HSA-5663205
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S DNA Damage Checkpoints R-HSA-69615
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G1 phase and G1/S transition R-HSA-453279
PCP/CE pathway R-HSA-4086400
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transcriptional regulation by RUNX1 R-HSA-8878171
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Stabilization of p53 R-HSA-69541
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by WNT R-HSA-195721
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic G2-G2/M phases R-HSA-453274
Degradation of GLI1 by the proteasome R-HSA-5610780
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cyclin E associated events during G1/S transition R-HSA-69202
Assembly of the pre-replicative complex R-HSA-68867
Beta-catenin independent WNT signaling R-HSA-3858494
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Regulation of RAS by GAPs R-HSA-5658442
Signaling by NOTCH R-HSA-157118
Mitotic Anaphase R-HSA-68882
Metabolism of polyamines R-HSA-351202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Separation of Sister Chromatids R-HSA-2467813
S Phase R-HSA-69242
Innate Immune System R-HSA-168249
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PTEN Regulation R-HSA-6807070
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of beta-catenin by the destruction complex R-HSA-195253
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Developmental Biology R-HSA-1266738
Downstream TCR signaling R-HSA-202424
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog ligand biogenesis R-HSA-5358346
ER-Phagosome pathway R-HSA-1236974
Cellular response to chemical stress R-HSA-9711123
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transport of small molecules R-HSA-382551
Ub-specific processing proteases R-HSA-5689880
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of DVL R-HSA-4641258
TCF dependent signaling in response to WNT R-HSA-201681
Deubiquitination R-HSA-5688426
Neddylation R-HSA-8951664
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 signaling R-HSA-9020702
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCR signaling R-HSA-202403
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of Apoptosis R-HSA-169911
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Vpu mediated degradation of CD4 R-HSA-180534
FCERI mediated NF-kB activation R-HSA-2871837
Adaptive Immune System R-HSA-1280218
Hedgehog 'off' state R-HSA-5610787
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Hh mutants are degraded by ERAD R-HSA-5362768
Interleukin-1 family signaling R-HSA-446652
Asymmetric localization of PCP proteins R-HSA-4608870
SARS-CoV-1 Infection R-HSA-9678108
DNA Replication R-HSA-69306
M Phase R-HSA-68886
CLEC7A (Dectin-1) signaling R-HSA-5607764
Class I MHC mediated antigen processing & presentation R-HSA-983169
SARS-CoV-1-host interactions R-HSA-9692914
Apoptosis R-HSA-109581
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
UCH proteinases R-HSA-5689603
Degradation of GLI2 by the proteasome R-HSA-5610783
Switching of origins to a post-replicative state R-HSA-69052
ABC transporter disorders R-HSA-5619084
SARS-CoV Infections R-HSA-9679506
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
p53-Independent DNA Damage Response R-HSA-69610
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC-family proteins mediated transport R-HSA-382556
Orc1 removal from chromatin R-HSA-68949
Cellular response to hypoxia R-HSA-1234174
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by Interleukins R-HSA-449147
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of AXIN R-HSA-4641257
Programmed Cell Death R-HSA-5357801
HIV Infection R-HSA-162906
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Immune System R-HSA-168256
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cell Cycle Checkpoints R-HSA-69620
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Hedgehog R-HSA-5358351
Developmental Biology R-HSA-1266738
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants are degraded by ERAD R-HSA-5362768
Programmed Cell Death R-HSA-5357801
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of beta-catenin by the destruction complex R-HSA-195253
S Phase R-HSA-69242
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX1 R-HSA-8878171
Defective CFTR causes cystic fibrosis R-HSA-5678895
Gene expression (Transcription) R-HSA-74160
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
Disorders of transmembrane transporters R-HSA-5619115
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PTEN Regulation R-HSA-6807070
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by WNT R-HSA-195721
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ER-Phagosome pathway R-HSA-1236974
Signaling by ROBO receptors R-HSA-376176
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by Hedgehog R-HSA-5358351
Synthesis of DNA R-HSA-69239
Regulation of RAS by GAPs R-HSA-5658442
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of amino acids and derivatives R-HSA-71291
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cytokine Signaling in Immune system R-HSA-1280215
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic Anaphase R-HSA-68882
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Generic Transcription Pathway R-HSA-212436
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Regulation of mitotic cell cycle R-HSA-453276
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
PIP3 activates AKT signaling R-HSA-1257604
Post-translational protein modification R-HSA-597592
Transport of small molecules R-HSA-382551
Beta-catenin independent WNT signaling R-HSA-3858494
SARS-CoV Infections R-HSA-9679506
Signal Transduction R-HSA-162582
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Vif-mediated degradation of APOBEC3G R-HSA-180585
Nuclear events mediated by NFE2L2 R-HSA-9759194
Immune System R-HSA-168256
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by Interleukins R-HSA-449147
Degradation of AXIN R-HSA-4641257
Cell Cycle Checkpoints R-HSA-69620
Metabolism of polyamines R-HSA-351202
SARS-CoV-1 Infection R-HSA-9678108
DNA Replication Pre-Initiation R-HSA-69002
Cellular responses to stimuli R-HSA-8953897
Regulation of Apoptosis R-HSA-169911
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
G1/S Transition R-HSA-69206
Hedgehog ligand biogenesis R-HSA-5358346
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RAF/MAP kinase cascade R-HSA-5673001
Orc1 removal from chromatin R-HSA-68949
Cellular response to chemical stress R-HSA-9711123
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Checkpoints R-HSA-69481
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PCP/CE pathway R-HSA-4086400
Hh mutants abrogate ligand secretion R-HSA-5387390
Neddylation R-HSA-8951664
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCR signaling R-HSA-202403
Antigen processing-Cross presentation R-HSA-1236975
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Switching of origins to a post-replicative state R-HSA-69052
Degradation of DVL R-HSA-4641258
Nervous system development R-HSA-9675108
Interleukin-1 signaling R-HSA-9020702
UCH proteinases R-HSA-5689603
HIV Infection R-HSA-162906
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Metabolism of proteins R-HSA-392499
Degradation of GLI2 by the proteasome R-HSA-5610783
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Deubiquitination R-HSA-5688426
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Host Interactions of HIV factors R-HSA-162909
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI1 by the proteasome R-HSA-5610780
SARS-CoV-1-host interactions R-HSA-9692914
RNA Polymerase II Transcription R-HSA-73857
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX2 R-HSA-8878166
M Phase R-HSA-68886
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ABC transporter disorders R-HSA-5619084
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Stabilization of p53 R-HSA-69541
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by ROBO receptors R-HSA-376176
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of proteins R-HSA-392499
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Disorders of transmembrane transporters R-HSA-5619115
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hh mutants are degraded by ERAD R-HSA-5362768
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
SARS-CoV-1 Infection R-HSA-9678108
Metabolism of amino acids and derivatives R-HSA-71291
Asymmetric localization of PCP proteins R-HSA-4608870
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by Hedgehog R-HSA-5358351
DNA Replication R-HSA-69306
RNA Polymerase II Transcription R-HSA-73857
Deubiquitination R-HSA-5688426
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
M Phase R-HSA-68886
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
Signaling by WNT R-HSA-195721
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of AXIN R-HSA-4641257
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RAS by GAPs R-HSA-5658442
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Intracellular signaling by second messengers R-HSA-9006925
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Checkpoints R-HSA-69481
FCERI mediated NF-kB activation R-HSA-2871837
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants abrogate ligand secretion R-HSA-5387390
Post-translational protein modification R-HSA-597592
Developmental Biology R-HSA-1266738
Stabilization of p53 R-HSA-69541
Interleukin-1 family signaling R-HSA-446652
Mitotic G2-G2/M phases R-HSA-453274
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
Cell Cycle R-HSA-1640170
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular responses to stimuli R-HSA-8953897
Host Interactions of HIV factors R-HSA-162909
Vpu mediated degradation of CD4 R-HSA-180534
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by NOTCH R-HSA-157118
DNA Replication Pre-Initiation R-HSA-69002
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream TCR signaling R-HSA-202424
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
HIV Infection R-HSA-162906
Axon guidance R-HSA-422475
SARS-CoV-1-host interactions R-HSA-9692914
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by NOTCH4 R-HSA-9013694
p53-Independent DNA Damage Response R-HSA-69610
ER-Phagosome pathway R-HSA-1236974
Signal Transduction R-HSA-162582
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Immune System R-HSA-168256
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX2 expression and activity R-HSA-8939902
Transport of small molecules R-HSA-382551
G2/M Transition R-HSA-69275
RAF/MAP kinase cascade R-HSA-5673001
ABC-family proteins mediated transport R-HSA-382556
Disease R-HSA-1643685
Separation of Sister Chromatids R-HSA-2467813
PCP/CE pathway R-HSA-4086400
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC transporter disorders R-HSA-5619084
Orc1 removal from chromatin R-HSA-68949
Regulation of mitotic cell cycle R-HSA-453276
Cellular response to chemical stress R-HSA-9711123
Hedgehog ligand biogenesis R-HSA-5358346
Adaptive Immune System R-HSA-1280218
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Switching of origins to a post-replicative state R-HSA-69052
PIP3 activates AKT signaling R-HSA-1257604
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of polyamines R-HSA-351202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Anaphase R-HSA-68882
Cell Cycle, Mitotic R-HSA-69278
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G1 phase and G1/S transition R-HSA-453279
Negative regulation of NOTCH4 signaling R-HSA-9604323
Assembly of the pre-replicative complex R-HSA-68867
SARS-CoV Infections R-HSA-9679506
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TCF dependent signaling in response to WNT R-HSA-201681
G1/S DNA Damage Checkpoints R-HSA-69615
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cell Cycle Checkpoints R-HSA-69620
Beta-catenin independent WNT signaling R-HSA-3858494
Neddylation R-HSA-8951664
Synthesis of DNA R-HSA-69239
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Apoptosis R-HSA-109581
C-type lectin receptors (CLRs) R-HSA-5621481
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK family signaling cascades R-HSA-5683057
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
G1/S Transition R-HSA-69206
Metabolism R-HSA-1430728
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular response to hypoxia R-HSA-1234174
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Mitotic Metaphase and Anaphase R-HSA-2555396
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
UCH proteinases R-HSA-5689603

Expression Atlas ENSG00000100519
NCBI gene (formerly Entrezgene) 5706
GeneCards 9553
HGNC Symbol HGNC:9553
MIM gene 602708
UniProtKB Gene Name P62333
WikiGene 5706
Gene: PSMD3
Ensembl ID : ENSG00000108344
Description: proteasome 26S subunit, non-ATPase 3
Gene Synonyms: P58,RPN3,S3,TSTA2
5 APIs:
94 Possible Orthologues:

Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Apoptosis R-HSA-109581
Axon guidance R-HSA-422475
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of amino acids and derivatives R-HSA-71291
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of mitotic cell cycle R-HSA-453276
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Mitotic G1 phase and G1/S transition R-HSA-453279
Disease R-HSA-1643685
Mitotic Metaphase and Anaphase R-HSA-2555396
TCR signaling R-HSA-202403
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Switching of origins to a post-replicative state R-HSA-69052
Antigen processing-Cross presentation R-HSA-1236975
S Phase R-HSA-69242
Signaling by ROBO receptors R-HSA-376176
Asymmetric localization of PCP proteins R-HSA-4608870
ABC transporter disorders R-HSA-5619084
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC-family proteins mediated transport R-HSA-382556
Ub-specific processing proteases R-HSA-5689880
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
TCF dependent signaling in response to WNT R-HSA-201681
Stabilization of p53 R-HSA-69541
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neddylation R-HSA-8951664
Hh mutants are degraded by ERAD R-HSA-5362768
RNA Polymerase II Transcription R-HSA-73857
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Programmed Cell Death R-HSA-5357801
G2/M Transition R-HSA-69275
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Synthesis of DNA R-HSA-69239
Intracellular signaling by second messengers R-HSA-9006925
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
p53-Independent DNA Damage Response R-HSA-69610
Immune System R-HSA-168256
Signaling by NOTCH R-HSA-157118
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of Apoptosis R-HSA-169911
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Neutrophil degranulation R-HSA-6798695
RAF/MAP kinase cascade R-HSA-5673001
Degradation of AXIN R-HSA-4641257
Signaling by Hedgehog R-HSA-5358351
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
Adaptive Immune System R-HSA-1280218
UCH proteinases R-HSA-5689603
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transcriptional regulation by RUNX2 R-HSA-8878166
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by NOTCH4 R-HSA-9013694
Cytokine Signaling in Immune system R-HSA-1280215
Nervous system development R-HSA-9675108
Interleukin-1 family signaling R-HSA-446652
C-type lectin receptors (CLRs) R-HSA-5621481
Assembly of the pre-replicative complex R-HSA-68867
M Phase R-HSA-68886
Downstream TCR signaling R-HSA-202424
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of proteins R-HSA-392499
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Deubiquitination R-HSA-5688426
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle R-HSA-1640170
DNA Replication R-HSA-69306
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
KEAP1-NFE2L2 pathway R-HSA-9755511
Activation of NF-kappaB in B cells R-HSA-1169091
HIV Infection R-HSA-162906
ER-Phagosome pathway R-HSA-1236974
Axon guidance R-HSA-422475
Degradation of beta-catenin by the destruction complex R-HSA-195253
Gene expression (Transcription) R-HSA-74160
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Disorders of transmembrane transporters R-HSA-5619115
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism R-HSA-1430728
Cellular responses to stress R-HSA-2262752
Mitotic Anaphase R-HSA-68882
PIP3 activates AKT signaling R-HSA-1257604
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Separation of Sister Chromatids R-HSA-2467813
Infectious disease R-HSA-5663205
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK6/MAPK4 signaling R-HSA-5687128
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Orc1 removal from chromatin R-HSA-68949
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Checkpoints R-HSA-69481
PTEN Regulation R-HSA-6807070
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by WNT R-HSA-195721
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
FCERI mediated NF-kB activation R-HSA-2871837
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'on' state R-HSA-5632684
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 signaling R-HSA-9020702
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stimuli R-HSA-8953897
Transport of small molecules R-HSA-382551
DNA Replication Pre-Initiation R-HSA-69002
Apoptosis R-HSA-109581
Degradation of DVL R-HSA-4641258
Hedgehog ligand biogenesis R-HSA-5358346
MAPK1/MAPK3 signaling R-HSA-5684996
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G1/S Transition R-HSA-69206
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular response to hypoxia R-HSA-1234174
Regulation of RUNX2 expression and activity R-HSA-8939902
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Neddylation R-HSA-8951664
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
M Phase R-HSA-68886
Stabilization of p53 R-HSA-69541
Cellular responses to stimuli R-HSA-8953897
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of proteins R-HSA-392499
RAF/MAP kinase cascade R-HSA-5673001
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCR signaling R-HSA-202403
Asymmetric localization of PCP proteins R-HSA-4608870
G1/S DNA Damage Checkpoints R-HSA-69615
Deubiquitination R-HSA-5688426
Metabolism R-HSA-1430728
Generic Transcription Pathway R-HSA-212436
Nervous system development R-HSA-9675108
HIV Infection R-HSA-162906
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Axon guidance R-HSA-422475
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle Checkpoints R-HSA-69620
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RNA Polymerase II Transcription R-HSA-73857
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of polyamines R-HSA-351202
PCP/CE pathway R-HSA-4086400
Disorders of transmembrane transporters R-HSA-5619115
Orc1 removal from chromatin R-HSA-68949
Cellular response to hypoxia R-HSA-1234174
KEAP1-NFE2L2 pathway R-HSA-9755511
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH4 R-HSA-9013694
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
S Phase R-HSA-69242
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
Metabolism of amino acids and derivatives R-HSA-71291
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Regulation of Apoptosis R-HSA-169911
Degradation of DVL R-HSA-4641258
DNA Replication R-HSA-69306
Degradation of GLI2 by the proteasome R-HSA-5610783
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
Signaling by WNT R-HSA-195721
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle, Mitotic R-HSA-69278
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hh mutants abrogate ligand secretion R-HSA-5387390
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Separation of Sister Chromatids R-HSA-2467813
p53-Independent DNA Damage Response R-HSA-69610
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stress R-HSA-2262752
Mitotic G1 phase and G1/S transition R-HSA-453279
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transport of small molecules R-HSA-382551
Transcriptional regulation by RUNX2 R-HSA-8878166
Adaptive Immune System R-HSA-1280218
Signaling by Interleukins R-HSA-449147
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of RNA R-HSA-8953854
Gene expression (Transcription) R-HSA-74160
Programmed Cell Death R-HSA-5357801
Vpu mediated degradation of CD4 R-HSA-180534
Neutrophil degranulation R-HSA-6798695
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-1 signaling R-HSA-9020702
MAPK6/MAPK4 signaling R-HSA-5687128
Synthesis of DNA R-HSA-69239
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Developmental Biology R-HSA-1266738
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK1/MAPK3 signaling R-HSA-5684996
DNA Replication Pre-Initiation R-HSA-69002
MAPK family signaling cascades R-HSA-5683057
Downstream TCR signaling R-HSA-202424
Antigen processing-Cross presentation R-HSA-1236975
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of AXIN R-HSA-4641257
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
C-type lectin receptors (CLRs) R-HSA-5621481
Ub-specific processing proteases R-HSA-5689880
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Transition R-HSA-69275
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PTEN Regulation R-HSA-6807070
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cytokine Signaling in Immune system R-HSA-1280215
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Innate Immune System R-HSA-168249
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
UCH proteinases R-HSA-5689603
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'on' state R-HSA-5632684
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
ABC-family proteins mediated transport R-HSA-382556
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 family signaling R-HSA-446652
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by NOTCH R-HSA-157118
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of mitotic cell cycle R-HSA-453276
Mitotic Anaphase R-HSA-68882
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
Vpu mediated degradation of CD4 R-HSA-180534
Nervous system development R-HSA-9675108
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Developmental Biology R-HSA-1266738
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RAS by GAPs R-HSA-5658442
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G1/S Transition R-HSA-69206
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
Signaling by NOTCH R-HSA-157118
TCR signaling R-HSA-202403
S Phase R-HSA-69242
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of GLI1 by the proteasome R-HSA-5610780
Cell Cycle Checkpoints R-HSA-69620
Signal Transduction R-HSA-162582
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of polyamines R-HSA-351202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
ABC transporter disorders R-HSA-5619084
Degradation of DVL R-HSA-4641258
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
RNA Polymerase II Transcription R-HSA-73857
PCP/CE pathway R-HSA-4086400
PTEN Regulation R-HSA-6807070
Programmed Cell Death R-HSA-5357801
Downstream TCR signaling R-HSA-202424
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of beta-catenin by the destruction complex R-HSA-195253
Ub-specific processing proteases R-HSA-5689880
Cellular response to chemical stress R-HSA-9711123
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by NOTCH4 R-HSA-9013694
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cyclin E associated events during G1/S transition R-HSA-69202
UCH proteinases R-HSA-5689603
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI2 by the proteasome R-HSA-5610783
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neddylation R-HSA-8951664
Hedgehog 'off' state R-HSA-5610787
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of AXIN R-HSA-4641257
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
p53-Dependent G1 DNA Damage Response R-HSA-69563
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
DNA Replication Pre-Initiation R-HSA-69002
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular response to hypoxia R-HSA-1234174
C-type lectin receptors (CLRs) R-HSA-5621481
Switching of origins to a post-replicative state R-HSA-69052
Mitotic Anaphase R-HSA-68882
Transport of small molecules R-HSA-382551
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by Hedgehog R-HSA-5358351
Apoptosis R-HSA-109581
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cytokine Signaling in Immune system R-HSA-1280215
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Activation of NF-kappaB in B cells R-HSA-1169091
HIV Infection R-HSA-162906
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RUNX2 expression and activity R-HSA-8939902
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Gene expression (Transcription) R-HSA-74160
DNA Replication R-HSA-69306
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Infectious disease R-HSA-5663205
Regulation of mitotic cell cycle R-HSA-453276
Intracellular signaling by second messengers R-HSA-9006925
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Axon guidance R-HSA-422475
p53-Independent DNA Damage Response R-HSA-69610
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
ER-Phagosome pathway R-HSA-1236974
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of amino acids and derivatives R-HSA-71291
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by Interleukins R-HSA-449147
Separation of Sister Chromatids R-HSA-2467813
RAF/MAP kinase cascade R-HSA-5673001
TCF dependent signaling in response to WNT R-HSA-201681
Antigen processing-Cross presentation R-HSA-1236975
Neutrophil degranulation R-HSA-6798695
Interleukin-1 signaling R-HSA-9020702
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Stabilization of p53 R-HSA-69541
Adaptive Immune System R-HSA-1280218
Assembly of the pre-replicative complex R-HSA-68867
Deubiquitination R-HSA-5688426
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of RNA R-HSA-8953854
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Mitotic G2-G2/M phases R-HSA-453274
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of proteins R-HSA-392499
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX2 R-HSA-8878166
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by ROBO receptors R-HSA-376176
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Vif-mediated degradation of APOBEC3G R-HSA-180585
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
DNA Replication R-HSA-69306
Transcriptional regulation by RUNX2 R-HSA-8878166
Antigen processing-Cross presentation R-HSA-1236975
PTEN Regulation R-HSA-6807070
Regulation of RAS by GAPs R-HSA-5658442
PCP/CE pathway R-HSA-4086400
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Separation of Sister Chromatids R-HSA-2467813
Hh mutants are degraded by ERAD R-HSA-5362768
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transport of small molecules R-HSA-382551
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
Vpu mediated degradation of CD4 R-HSA-180534
S Phase R-HSA-69242
Cellular response to hypoxia R-HSA-1234174
MAPK1/MAPK3 signaling R-HSA-5684996
Assembly of the pre-replicative complex R-HSA-68867
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Infectious disease R-HSA-5663205
Cell Cycle R-HSA-1640170
Cytokine Signaling in Immune system R-HSA-1280215
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin E associated events during G1/S transition R-HSA-69202
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
M Phase R-HSA-68886
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Generic Transcription Pathway R-HSA-212436
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog ligand biogenesis R-HSA-5358346
ABC transporter disorders R-HSA-5619084
Ub-specific processing proteases R-HSA-5689880
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by ROBO receptors R-HSA-376176
Interleukin-1 family signaling R-HSA-446652
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Synthesis of DNA R-HSA-69239
Degradation of DVL R-HSA-4641258
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Switching of origins to a post-replicative state R-HSA-69052
Programmed Cell Death R-HSA-5357801
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by Interleukins R-HSA-449147
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Adaptive Immune System R-HSA-1280218
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Independent DNA Damage Response R-HSA-69610
RAF/MAP kinase cascade R-HSA-5673001
Mitotic Anaphase R-HSA-68882
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Degradation of AXIN R-HSA-4641257
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
Degradation of beta-catenin by the destruction complex R-HSA-195253
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of GLI1 by the proteasome R-HSA-5610780
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of Apoptosis R-HSA-169911
Signaling by WNT R-HSA-195721
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
Cellular response to chemical stress R-HSA-9711123
G2/M Transition R-HSA-69275
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Asymmetric localization of PCP proteins R-HSA-4608870
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Apoptosis R-HSA-109581
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH4 R-HSA-9013694
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of polyamines R-HSA-351202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
HIV Infection R-HSA-162906
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G2/M Checkpoints R-HSA-69481
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transcriptional regulation by RUNX1 R-HSA-8878171
Post-translational protein modification R-HSA-597592
Immune System R-HSA-168256
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of proteins R-HSA-392499
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX3 R-HSA-8878159
Neutrophil degranulation R-HSA-6798695
Degradation of GLI2 by the proteasome R-HSA-5610783
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
Signaling by NOTCH R-HSA-157118
Metabolism of RNA R-HSA-8953854
Nervous system development R-HSA-9675108
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of PTEN stability and activity R-HSA-8948751
KEAP1-NFE2L2 pathway R-HSA-9755511
Signal Transduction R-HSA-162582
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stimuli R-HSA-8953897
Activation of NF-kappaB in B cells R-HSA-1169091
TCF dependent signaling in response to WNT R-HSA-201681
G1/S Transition R-HSA-69206
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'on' state R-HSA-5632684
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RUNX2 expression and activity R-HSA-8939902
Disorders of transmembrane transporters R-HSA-5619115
Neddylation R-HSA-8951664
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stress R-HSA-2262752
Defective CFTR causes cystic fibrosis R-HSA-5678895
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
Switching of origins to a post-replicative state R-HSA-69052
Regulation of RAS by GAPs R-HSA-5658442
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle, Mitotic R-HSA-69278
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular response to hypoxia R-HSA-1234174
ABC transporter disorders R-HSA-5619084
Cell Cycle R-HSA-1640170
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ER-Phagosome pathway R-HSA-1236974
Hedgehog ligand biogenesis R-HSA-5358346
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neddylation R-HSA-8951664
Cell Cycle Checkpoints R-HSA-69620
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by NOTCH R-HSA-157118
M Phase R-HSA-68886
Adaptive Immune System R-HSA-1280218
Apoptosis R-HSA-109581
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Gene expression (Transcription) R-HSA-74160
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic G1 phase and G1/S transition R-HSA-453279
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
Intracellular signaling by second messengers R-HSA-9006925
DNA Replication Pre-Initiation R-HSA-69002
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants are degraded by ERAD R-HSA-5362768
p53-Dependent G1 DNA Damage Response R-HSA-69563
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX2 R-HSA-8878166
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Class I MHC mediated antigen processing & presentation R-HSA-983169
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Post-translational protein modification R-HSA-597592
Hedgehog 'on' state R-HSA-5632684
RNA Polymerase II Transcription R-HSA-73857
Ub-specific processing proteases R-HSA-5689880
Mitotic G2-G2/M phases R-HSA-453274
Beta-catenin independent WNT signaling R-HSA-3858494
Signal Transduction R-HSA-162582
Signaling by WNT R-HSA-195721
Signaling by Hedgehog R-HSA-5358351
Disorders of transmembrane transporters R-HSA-5619115
Metabolism R-HSA-1430728
Degradation of beta-catenin by the destruction complex R-HSA-195253
Synthesis of DNA R-HSA-69239
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic Anaphase R-HSA-68882
p53-Independent DNA Damage Response R-HSA-69610
TCR signaling R-HSA-202403
Nuclear events mediated by NFE2L2 R-HSA-9759194
Downstream TCR signaling R-HSA-202424
Deubiquitination R-HSA-5688426
Signaling by ROBO receptors R-HSA-376176
MAPK6/MAPK4 signaling R-HSA-5687128
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of AXIN R-HSA-4641257
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX3 R-HSA-8878159
Infectious disease R-HSA-5663205
Regulation of RUNX2 expression and activity R-HSA-8939902
FCERI mediated NF-kB activation R-HSA-2871837
Transport of small molecules R-HSA-382551
Regulation of Apoptosis R-HSA-169911
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Nervous system development R-HSA-9675108
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Separation of Sister Chromatids R-HSA-2467813
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
PIP3 activates AKT signaling R-HSA-1257604
Axon guidance R-HSA-422475
Orc1 removal from chromatin R-HSA-68949
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Stabilization of p53 R-HSA-69541
G1/S DNA Damage Checkpoints R-HSA-69615
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PCP/CE pathway R-HSA-4086400
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hh mutants abrogate ligand secretion R-HSA-5387390
PTEN Regulation R-HSA-6807070
Mitotic Metaphase and Anaphase R-HSA-2555396
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by NOTCH4 R-HSA-9013694
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX3 expression and activity R-HSA-8941858
Programmed Cell Death R-HSA-5357801
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cytokine Signaling in Immune system R-HSA-1280215
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of RNA R-HSA-8953854
G2/M Checkpoints R-HSA-69481
Metabolism of proteins R-HSA-392499
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RAF/MAP kinase cascade R-HSA-5673001
HIV Infection R-HSA-162906
Metabolism of polyamines R-HSA-351202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
NIK-->noncanonical NF-kB signaling R-HSA-5676590
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Neutrophil degranulation R-HSA-6798695
UCH proteinases R-HSA-5689603
Cellular response to chemical stress R-HSA-9711123
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G1/S Transition R-HSA-69206
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Immune System R-HSA-168256
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1 DNA Damage Response R-HSA-69563
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by NOTCH4 R-HSA-9013694
Neddylation R-HSA-8951664
Signaling by WNT R-HSA-195721
Cell Cycle Checkpoints R-HSA-69620
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Post-translational protein modification R-HSA-597592
Signaling by ROBO receptors R-HSA-376176
Downstream TCR signaling R-HSA-202424
Signal Transduction R-HSA-162582
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Developmental Biology R-HSA-1266738
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular response to chemical stress R-HSA-9711123
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Hedgehog R-HSA-5358351
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication R-HSA-69306
Stabilization of p53 R-HSA-69541
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle, Mitotic R-HSA-69278
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
M Phase R-HSA-68886
Infectious disease R-HSA-5663205
Mitotic G2-G2/M phases R-HSA-453274
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
DNA Replication Pre-Initiation R-HSA-69002
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vif-mediated degradation of APOBEC3G R-HSA-180585
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK6/MAPK4 signaling R-HSA-5687128
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of polyamines R-HSA-351202
Defective CFTR causes cystic fibrosis R-HSA-5678895
Axon guidance R-HSA-422475
PCP/CE pathway R-HSA-4086400
Degradation of DVL R-HSA-4641258
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ub-specific processing proteases R-HSA-5689880
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RAF/MAP kinase cascade R-HSA-5673001
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Separation of Sister Chromatids R-HSA-2467813
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of amino acids and derivatives R-HSA-71291
Innate Immune System R-HSA-168249
Assembly of the pre-replicative complex R-HSA-68867
Programmed Cell Death R-HSA-5357801
Switching of origins to a post-replicative state R-HSA-69052
Deubiquitination R-HSA-5688426
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Anaphase R-HSA-68882
Disease R-HSA-1643685
Degradation of beta-catenin by the destruction complex R-HSA-195253
Mitotic G1 phase and G1/S transition R-HSA-453279
Generic Transcription Pathway R-HSA-212436
Metabolism R-HSA-1430728
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
G2/M Checkpoints R-HSA-69481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Beta-catenin independent WNT signaling R-HSA-3858494
Gene expression (Transcription) R-HSA-74160
Nuclear events mediated by NFE2L2 R-HSA-9759194
KEAP1-NFE2L2 pathway R-HSA-9755511
UCH proteinases R-HSA-5689603
Vpu mediated degradation of CD4 R-HSA-180534
ABC-family proteins mediated transport R-HSA-382556
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cytokine Signaling in Immune system R-HSA-1280215
Neutrophil degranulation R-HSA-6798695
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
MAPK family signaling cascades R-HSA-5683057
G1/S Transition R-HSA-69206
Interleukin-1 family signaling R-HSA-446652
ABC transporter disorders R-HSA-5619084
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ER-Phagosome pathway R-HSA-1236974
PTEN Regulation R-HSA-6807070
CLEC7A (Dectin-1) signaling R-HSA-5607764
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular responses to stress R-HSA-2262752
Signaling by NOTCH R-HSA-157118
Cell Cycle R-HSA-1640170
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by Interleukins R-HSA-449147
Host Interactions of HIV factors R-HSA-162909
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog ligand biogenesis R-HSA-5358346
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX1 R-HSA-8878171
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of proteins R-HSA-392499
HIV Infection R-HSA-162906
Regulation of RUNX2 expression and activity R-HSA-8939902
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX2 R-HSA-8878166
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
Cellular response to hypoxia R-HSA-1234174
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transport of small molecules R-HSA-382551
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nervous system development R-HSA-9675108
TCR signaling R-HSA-202403
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of RNA R-HSA-8953854
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of Apoptosis R-HSA-169911
Synthesis of DNA R-HSA-69239
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of AXIN R-HSA-4641257
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular responses to stress R-HSA-2262752
MAPK1/MAPK3 signaling R-HSA-5684996
ABC-family proteins mediated transport R-HSA-382556
Beta-catenin independent WNT signaling R-HSA-3858494
ABC transporter disorders R-HSA-5619084
Post-translational protein modification R-HSA-597592
Hh mutants abrogate ligand secretion R-HSA-5387390
Asymmetric localization of PCP proteins R-HSA-4608870
Mitotic G2-G2/M phases R-HSA-453274
Metabolism R-HSA-1430728
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
M Phase R-HSA-68886
MAPK family signaling cascades R-HSA-5683057
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
RNA Polymerase II Transcription R-HSA-73857
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Separation of Sister Chromatids R-HSA-2467813
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Adaptive Immune System R-HSA-1280218
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular response to chemical stress R-HSA-9711123
PCP/CE pathway R-HSA-4086400
p53-Independent DNA Damage Response R-HSA-69610
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Nervous system development R-HSA-9675108
Regulation of RUNX2 expression and activity R-HSA-8939902
Hh mutants are degraded by ERAD R-HSA-5362768
Assembly of the pre-replicative complex R-HSA-68867
DNA Replication R-HSA-69306
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S Transition R-HSA-69206
Cellular responses to stimuli R-HSA-8953897
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Negative regulation of NOTCH4 signaling R-HSA-9604323
HIV Infection R-HSA-162906
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signal Transduction R-HSA-162582
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Immune System R-HSA-168256
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Switching of origins to a post-replicative state R-HSA-69052
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 family signaling R-HSA-446652
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hedgehog 'off' state R-HSA-5610787
Transport of small molecules R-HSA-382551
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Vif-mediated degradation of APOBEC3G R-HSA-180585
Downstream TCR signaling R-HSA-202424
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
Apoptosis R-HSA-109581
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mitotic cell cycle R-HSA-453276
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RAS by GAPs R-HSA-5658442
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FCERI mediated NF-kB activation R-HSA-2871837
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog 'on' state R-HSA-5632684
TCF dependent signaling in response to WNT R-HSA-201681
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Programmed Cell Death R-HSA-5357801
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Interleukin-1 signaling R-HSA-9020702
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cell Cycle, Mitotic R-HSA-69278
Stabilization of p53 R-HSA-69541
Hedgehog ligand biogenesis R-HSA-5358346
Innate Immune System R-HSA-168249
Intracellular signaling by second messengers R-HSA-9006925
Antigen processing-Cross presentation R-HSA-1236975
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of proteins R-HSA-392499
Mitotic Anaphase R-HSA-68882
Vpu mediated degradation of CD4 R-HSA-180534
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Axon guidance R-HSA-422475
Neutrophil degranulation R-HSA-6798695
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
S Phase R-HSA-69242
Cellular response to hypoxia R-HSA-1234174
p53-Dependent G1 DNA Damage Response R-HSA-69563
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCR signaling R-HSA-202403
Cell Cycle R-HSA-1640170
Stabilization of p53 R-HSA-69541
C-type lectin receptors (CLRs) R-HSA-5621481
Deubiquitination R-HSA-5688426
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
Post-translational protein modification R-HSA-597592
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events mediated by NFE2L2 R-HSA-9759194
PTEN Regulation R-HSA-6807070
Metabolism of RNA R-HSA-8953854
Cell Cycle Checkpoints R-HSA-69620
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic Metaphase and Anaphase R-HSA-2555396
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Apoptosis R-HSA-109581
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Degradation of AXIN R-HSA-4641257
Hedgehog 'on' state R-HSA-5632684
ABC transporter disorders R-HSA-5619084
Signaling by Interleukins R-HSA-449147
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by NOTCH R-HSA-157118
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX1 R-HSA-8878171
G1/S Transition R-HSA-69206
ABC-family proteins mediated transport R-HSA-382556
Disease R-HSA-1643685
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Independent DNA Damage Response R-HSA-69610
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Assembly of the pre-replicative complex R-HSA-68867
CLEC7A (Dectin-1) signaling R-HSA-5607764
ER-Phagosome pathway R-HSA-1236974
Innate Immune System R-HSA-168249
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
G1/S DNA Damage Checkpoints R-HSA-69615
Defective CFTR causes cystic fibrosis R-HSA-5678895
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX3 expression and activity R-HSA-8941858
Adaptive Immune System R-HSA-1280218
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle, Mitotic R-HSA-69278
Metabolism of proteins R-HSA-392499
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX2 R-HSA-8878166
Disorders of transmembrane transporters R-HSA-5619115
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of Apoptosis R-HSA-169911
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of RAS by GAPs R-HSA-5658442
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neutrophil degranulation R-HSA-6798695
Infectious disease R-HSA-5663205
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
Host Interactions of HIV factors R-HSA-162909
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Developmental Biology R-HSA-1266738
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stimuli R-HSA-8953897
Downstream TCR signaling R-HSA-202424
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX3 R-HSA-8878159
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hh mutants abrogate ligand secretion R-HSA-5387390
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
DNA Replication R-HSA-69306
Regulation of mitotic cell cycle R-HSA-453276
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog 'off' state R-HSA-5610787
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of amino acids and derivatives R-HSA-71291
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
Hh mutants are degraded by ERAD R-HSA-5362768
Nervous system development R-HSA-9675108
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stress R-HSA-2262752
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Intracellular signaling by second messengers R-HSA-9006925
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
Asymmetric localization of PCP proteins R-HSA-4608870
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
TCF dependent signaling in response to WNT R-HSA-201681
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
G2/M Transition R-HSA-69275
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ub-specific processing proteases R-HSA-5689880
Activation of NF-kappaB in B cells R-HSA-1169091
Orc1 removal from chromatin R-HSA-68949
PCP/CE pathway R-HSA-4086400
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog ligand biogenesis R-HSA-5358346
Gene expression (Transcription) R-HSA-74160
Neddylation R-HSA-8951664
Signaling by WNT R-HSA-195721
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by ROBO receptors R-HSA-376176
Transport of small molecules R-HSA-382551
Separation of Sister Chromatids R-HSA-2467813
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCR signaling R-HSA-202403
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of PTEN stability and activity R-HSA-8948751
MAPK6/MAPK4 signaling R-HSA-5687128

Expression Atlas ENSG00000108344
NCBI gene (formerly Entrezgene) 5709
GeneCards 9560
HGNC Symbol HGNC:9560
MIM gene 617676
UniProtKB Gene Name O43242
WikiGene 5709
Gene: SEM1
Ensembl ID : ENSG00000127922
Description: SEM1 26S proteasome subunit
Gene Synonyms: C7ORF76,DSS1,ECD,FLJ42280,PSMD15,SHFD1,SHFDG1,SHFM1,SHSF1
5 APIs:
156 Possible Orthologues:

Synthesis of DNA R-HSA-69239
Degradation of AXIN R-HSA-4641257
Metabolism R-HSA-1430728
Signaling by NOTCH R-HSA-157118
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX3 R-HSA-8878159
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism R-HSA-1430728
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Post-translational protein modification R-HSA-597592
Programmed Cell Death R-HSA-5357801
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TCR signaling R-HSA-202403
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Mitotic Metaphase and Anaphase R-HSA-2555396
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH R-HSA-157118
Signaling by WNT R-HSA-195721
Metabolism of RNA R-HSA-8953854
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream TCR signaling R-HSA-202424
Homology Directed Repair R-HSA-5693538
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX3 expression and activity R-HSA-8941858
C-type lectin receptors (CLRs) R-HSA-5621481
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Degradation of GLI1 by the proteasome R-HSA-5610780
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of amino acids and derivatives R-HSA-71291
S Phase R-HSA-69242
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Hh mutants are degraded by ERAD R-HSA-5362768
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of expression of SLITs and ROBOs R-HSA-9010553
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle, Mitotic R-HSA-69278
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Asymmetric localization of PCP proteins R-HSA-4608870
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Neddylation R-HSA-8951664
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication R-HSA-69306
PTEN Regulation R-HSA-6807070
CLEC7A (Dectin-1) signaling R-HSA-5607764
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent DNA Damage Response R-HSA-69610
DNA Double-Strand Break Repair R-HSA-5693532
Developmental Biology R-HSA-1266738
Degradation of DVL R-HSA-4641258
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Assembly of the pre-replicative complex R-HSA-68867
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
UCH proteinases R-HSA-5689603
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Cellular responses to stimuli R-HSA-8953897
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G1 phase and G1/S transition R-HSA-453279
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Defective CFTR causes cystic fibrosis R-HSA-5678895
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
HDR through Homologous Recombination (HRR) R-HSA-5685942
Intracellular signaling by second messengers R-HSA-9006925
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transport of small molecules R-HSA-382551
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of beta-catenin by the destruction complex R-HSA-195253
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Interleukin-1 family signaling R-HSA-446652
Interleukin-1 signaling R-HSA-9020702
Hh mutants abrogate ligand secretion R-HSA-5387390
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Mitotic G2-G2/M phases R-HSA-453274
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle R-HSA-1640170
Degradation of AXIN R-HSA-4641257
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
PIP3 activates AKT signaling R-HSA-1257604
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Interleukins R-HSA-449147
Infectious disease R-HSA-5663205
Ub-specific processing proteases R-HSA-5689880
Nervous system development R-HSA-9675108
Nuclear events mediated by NFE2L2 R-HSA-9759194
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ABC-family proteins mediated transport R-HSA-382556
Regulation of Apoptosis R-HSA-169911
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disease R-HSA-1643685
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
M Phase R-HSA-68886
Negative regulation of NOTCH4 signaling R-HSA-9604323
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mitotic cell cycle R-HSA-453276
Adaptive Immune System R-HSA-1280218
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of polyamines R-HSA-351202
DNA Repair R-HSA-73894
ER-Phagosome pathway R-HSA-1236974
Stabilization of p53 R-HSA-69541
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
Hedgehog 'on' state R-HSA-5632684
MAPK6/MAPK4 signaling R-HSA-5687128
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
DNA Replication Pre-Initiation R-HSA-69002
Resolution of D-Loop Structures R-HSA-5693537
G2/M Checkpoints R-HSA-69481
MAPK family signaling cascades R-HSA-5683057
Signaling by Hedgehog R-HSA-5358351
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Generic Transcription Pathway R-HSA-212436
Cell Cycle Checkpoints R-HSA-69620
Disorders of transmembrane transporters R-HSA-5619115
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Signal Transduction R-HSA-162582
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular response to chemical stress R-HSA-9711123
Cyclin E associated events during G1/S transition R-HSA-69202
Orc1 removal from chromatin R-HSA-68949
HIV Infection R-HSA-162906
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of DNA repair R-HSA-9675135
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Anaphase R-HSA-68882
Cytokine Signaling in Immune system R-HSA-1280215
p53-Dependent G1 DNA Damage Response R-HSA-69563
Assembly of the pre-replicative complex R-HSA-68867
Disorders of transmembrane transporters R-HSA-5619115
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hh mutants abrogate ligand secretion R-HSA-5387390
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G2-G2/M phases R-HSA-453274
Cellular responses to stress R-HSA-2262752
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Hedgehog R-HSA-5358351
DNA Replication R-HSA-69306
S Phase R-HSA-69242
Regulation of RAS by GAPs R-HSA-5658442
Degradation of DVL R-HSA-4641258
Cell Cycle R-HSA-1640170
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Neddylation R-HSA-8951664
DNA Replication Pre-Initiation R-HSA-69002
p53-Independent DNA Damage Response R-HSA-69610
Programmed Cell Death R-HSA-5357801
Metabolism of polyamines R-HSA-351202
Generic Transcription Pathway R-HSA-212436
RAF/MAP kinase cascade R-HSA-5673001
PCP/CE pathway R-HSA-4086400
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Apoptosis R-HSA-109581
Signaling by the B Cell Receptor (BCR) R-HSA-983705
MAPK6/MAPK4 signaling R-HSA-5687128
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of beta-catenin by the destruction complex R-HSA-195253
HIV Infection R-HSA-162906
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signal Transduction R-HSA-162582
Homology Directed Repair R-HSA-5693538
Interleukin-1 family signaling R-HSA-446652
M Phase R-HSA-68886
Vpu mediated degradation of CD4 R-HSA-180534
Developmental Biology R-HSA-1266738
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
UCH proteinases R-HSA-5689603
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G2/M Transition R-HSA-69275
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Interleukin-1 signaling R-HSA-9020702
Degradation of GLI1 by the proteasome R-HSA-5610780
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular response to hypoxia R-HSA-1234174
Innate Immune System R-HSA-168249
Axon guidance R-HSA-422475
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TCR signaling R-HSA-202403
Cell Cycle, Mitotic R-HSA-69278
Metabolism of RNA R-HSA-8953854
Cellular response to chemical stress R-HSA-9711123
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
CLEC7A (Dectin-1) signaling R-HSA-5607764
Deubiquitination R-HSA-5688426
Orc1 removal from chromatin R-HSA-68949
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of mitotic cell cycle R-HSA-453276
Disease R-HSA-1643685
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Separation of Sister Chromatids R-HSA-2467813
G1/S DNA Damage Checkpoints R-HSA-69615
Nervous system development R-HSA-9675108
Cell Cycle Checkpoints R-HSA-69620
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
FCERI mediated NF-kB activation R-HSA-2871837
Stabilization of p53 R-HSA-69541
HDR through Homologous Recombination (HRR) R-HSA-5685942
TCF dependent signaling in response to WNT R-HSA-201681
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX2 R-HSA-8878166
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of DNA repair R-HSA-9675135
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Double-Strand Break Repair R-HSA-5693532
G1/S Transition R-HSA-69206
Hh mutants are degraded by ERAD R-HSA-5362768
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
DNA Repair R-HSA-73894
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Activation of NF-kappaB in B cells R-HSA-1169091
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Resolution of D-Loop Structures R-HSA-5693537
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism R-HSA-1430728
Regulation of PTEN stability and activity R-HSA-8948751
Nuclear events mediated by NFE2L2 R-HSA-9759194
RNA Polymerase II Transcription R-HSA-73857
Antigen processing-Cross presentation R-HSA-1236975
Mitotic G1 phase and G1/S transition R-HSA-453279
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Downstream TCR signaling R-HSA-202424
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
Gene expression (Transcription) R-HSA-74160
ABC-family proteins mediated transport R-HSA-382556
Synthesis of DNA R-HSA-69239
Metabolism of proteins R-HSA-392499
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'on' state R-HSA-5632684
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
ABC transporter disorders R-HSA-5619084
Cellular responses to stimuli R-HSA-8953897
Class I MHC mediated antigen processing & presentation R-HSA-983169
Transport of small molecules R-HSA-382551
PTEN Regulation R-HSA-6807070
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Immune System R-HSA-168256
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Infectious disease R-HSA-5663205
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
ER-Phagosome pathway R-HSA-1236974
Regulation of Apoptosis R-HSA-169911
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Switching of origins to a post-replicative state R-HSA-69052
Intracellular signaling by second messengers R-HSA-9006925
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Post-translational protein modification R-HSA-597592
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'off' state R-HSA-5610787
C-type lectin receptors (CLRs) R-HSA-5621481
Adaptive Immune System R-HSA-1280218
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic Anaphase R-HSA-68882
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Ub-specific processing proteases R-HSA-5689880
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Asymmetric localization of PCP proteins R-HSA-4608870
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Signaling by WNT R-HSA-195721
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transcriptional regulation by RUNX3 R-HSA-8878159
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Regulation of RUNX2 expression and activity R-HSA-8939902
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Orc1 removal from chromatin R-HSA-68949
Developmental Biology R-HSA-1266738
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G1/S Transition R-HSA-69206
Metabolism of amino acids and derivatives R-HSA-71291
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of Apoptosis R-HSA-169911
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by WNT R-HSA-195721
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Gene expression (Transcription) R-HSA-74160
Cellular response to hypoxia R-HSA-1234174
HDR through Homologous Recombination (HRR) R-HSA-5685942
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
PTEN Regulation R-HSA-6807070
Assembly of the pre-replicative complex R-HSA-68867
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Transition R-HSA-69275
Cyclin E associated events during G1/S transition R-HSA-69202
G2/M Checkpoints R-HSA-69481
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by NOTCH R-HSA-157118
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
HIV Infection R-HSA-162906
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of RNA R-HSA-8953854
TCR signaling R-HSA-202403
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
DNA Double-Strand Break Repair R-HSA-5693532
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Diseases of DNA repair R-HSA-9675135
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
Antigen processing-Cross presentation R-HSA-1236975
MAPK6/MAPK4 signaling R-HSA-5687128
Post-translational protein modification R-HSA-597592
Class I MHC mediated antigen processing & presentation R-HSA-983169
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 family signaling R-HSA-446652
Generic Transcription Pathway R-HSA-212436
Transport of small molecules R-HSA-382551
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Intracellular signaling by second messengers R-HSA-9006925
ER-Phagosome pathway R-HSA-1236974
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
CLEC7A (Dectin-1) signaling R-HSA-5607764
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Mitotic G1 phase and G1/S transition R-HSA-453279
Innate Immune System R-HSA-168249
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream TCR signaling R-HSA-202424
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC-family proteins mediated transport R-HSA-382556
Metabolism of polyamines R-HSA-351202
Adaptive Immune System R-HSA-1280218
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Negative regulation of NOTCH4 signaling R-HSA-9604323
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle, Mitotic R-HSA-69278
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stimuli R-HSA-8953897
Regulation of mitotic cell cycle R-HSA-453276
G1/S DNA Damage Checkpoints R-HSA-69615
Host Interactions of HIV factors R-HSA-162909
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
Deubiquitination R-HSA-5688426
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
DNA Replication Pre-Initiation R-HSA-69002
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of RAS by GAPs R-HSA-5658442
Signaling by ROBO receptors R-HSA-376176
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Vpu mediated degradation of CD4 R-HSA-180534
DNA Repair R-HSA-73894
Cellular response to chemical stress R-HSA-9711123
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Apoptosis R-HSA-109581
Signaling by Hedgehog R-HSA-5358351
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G2-G2/M phases R-HSA-453274
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX3 R-HSA-8878159
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
PCP/CE pathway R-HSA-4086400
Degradation of DVL R-HSA-4641258
Degradation of AXIN R-HSA-4641257
Asymmetric localization of PCP proteins R-HSA-4608870
Synthesis of DNA R-HSA-69239
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants are degraded by ERAD R-HSA-5362768
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
DNA Replication R-HSA-69306
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of GLI2 by the proteasome R-HSA-5610783
C-type lectin receptors (CLRs) R-HSA-5621481
Infectious disease R-HSA-5663205
Resolution of D-Loop Structures R-HSA-5693537
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX1 R-HSA-8878171
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants abrogate ligand secretion R-HSA-5387390
RNA Polymerase II Transcription R-HSA-73857
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Homology Directed Repair R-HSA-5693538
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Immune System R-HSA-168256
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hedgehog 'off' state R-HSA-5610787
Disorders of transmembrane transporters R-HSA-5619115
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by NOTCH4 R-HSA-9013694
M Phase R-HSA-68886
Cellular responses to stress R-HSA-2262752
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
Nervous system development R-HSA-9675108
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Separation of Sister Chromatids R-HSA-2467813
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'on' state R-HSA-5632684
S Phase R-HSA-69242
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vif-mediated degradation of APOBEC3G R-HSA-180585
G2/M Checkpoints R-HSA-69481
PCP/CE pathway R-HSA-4086400
p53-Independent DNA Damage Response R-HSA-69610
Metabolism R-HSA-1430728
Diseases of DNA repair R-HSA-9675135
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Interleukin-1 signaling R-HSA-9020702
DNA Replication Pre-Initiation R-HSA-69002
MAPK1/MAPK3 signaling R-HSA-5684996
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Gene expression (Transcription) R-HSA-74160
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Interleukin-1 family signaling R-HSA-446652
DNA Double-Strand Break Repair R-HSA-5693532
Signaling by Interleukins R-HSA-449147
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
Adaptive Immune System R-HSA-1280218
Mitotic Anaphase R-HSA-68882
Signaling by Hedgehog R-HSA-5358351
Cellular response to chemical stress R-HSA-9711123
Signal Transduction R-HSA-162582
Post-translational protein modification R-HSA-597592
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Infectious disease R-HSA-5663205
Regulation of Apoptosis R-HSA-169911
FCERI mediated NF-kB activation R-HSA-2871837
Hedgehog 'on' state R-HSA-5632684
Hedgehog 'off' state R-HSA-5610787
HIV Infection R-HSA-162906
p53-Dependent G1 DNA Damage Response R-HSA-69563
Disorders of transmembrane transporters R-HSA-5619115
Neddylation R-HSA-8951664
Regulation of RUNX3 expression and activity R-HSA-8941858
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic G1 phase and G1/S transition R-HSA-453279
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Transcriptional regulation by RUNX2 R-HSA-8878166
PTEN Regulation R-HSA-6807070
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Separation of Sister Chromatids R-HSA-2467813
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
KEAP1-NFE2L2 pathway R-HSA-9755511
Class I MHC mediated antigen processing & presentation R-HSA-983169
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S DNA Damage Checkpoints R-HSA-69615
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Synthesis of DNA R-HSA-69239
UCH proteinases R-HSA-5689603
TCF dependent signaling in response to WNT R-HSA-201681
Downstream TCR signaling R-HSA-202424
Apoptosis R-HSA-109581
Disease R-HSA-1643685
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Innate Immune System R-HSA-168249
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Transport of small molecules R-HSA-382551
Degradation of DVL R-HSA-4641258
Nuclear events mediated by NFE2L2 R-HSA-9759194
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Mitotic G2-G2/M phases R-HSA-453274
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
Assembly of the pre-replicative complex R-HSA-68867
DNA Replication R-HSA-69306
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
RNA Polymerase II Transcription R-HSA-73857
Resolution of D-Loop Structures R-HSA-5693537
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of beta-catenin by the destruction complex R-HSA-195253
Generic Transcription Pathway R-HSA-212436
HDR through Homologous Recombination (HRR) R-HSA-5685942
G1/S Transition R-HSA-69206
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Metabolism of amino acids and derivatives R-HSA-71291
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Homology Directed Repair R-HSA-5693538
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ABC-family proteins mediated transport R-HSA-382556
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of proteins R-HSA-392499
Programmed Cell Death R-HSA-5357801
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle, Mitotic R-HSA-69278
Regulation of mitotic cell cycle R-HSA-453276
ABC transporter disorders R-HSA-5619084
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Hedgehog ligand biogenesis R-HSA-5358346
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stimuli R-HSA-8953897
C-type lectin receptors (CLRs) R-HSA-5621481
Cytokine Signaling in Immune system R-HSA-1280215
ER-Phagosome pathway R-HSA-1236974
MAPK family signaling cascades R-HSA-5683057
Negative regulation of NOTCH4 signaling R-HSA-9604323
Deubiquitination R-HSA-5688426
Stabilization of p53 R-HSA-69541
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
PIP3 activates AKT signaling R-HSA-1257604
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Intracellular signaling by second messengers R-HSA-9006925
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by NOTCH4 R-HSA-9013694
Signaling by ROBO receptors R-HSA-376176
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
M Phase R-HSA-68886
Cell Cycle Checkpoints R-HSA-69620
Regulation of RUNX2 expression and activity R-HSA-8939902
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of RNA R-HSA-8953854
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX3 R-HSA-8878159
Immune System R-HSA-168256
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of AXIN R-HSA-4641257
S Phase R-HSA-69242
Ub-specific processing proteases R-HSA-5689880
DNA Repair R-HSA-73894
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Signaling by WNT R-HSA-195721
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
RAF/MAP kinase cascade R-HSA-5673001
Switching of origins to a post-replicative state R-HSA-69052
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
G2/M Transition R-HSA-69275
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PTEN Regulation R-HSA-6807070
Apoptosis R-HSA-109581
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Separation of Sister Chromatids R-HSA-2467813
Activation of NF-kappaB in B cells R-HSA-1169091
Innate Immune System R-HSA-168249
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Interleukin-1 signaling R-HSA-9020702
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
HIV Infection R-HSA-162906
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transport of small molecules R-HSA-382551
Cellular response to hypoxia R-HSA-1234174
DNA Replication Pre-Initiation R-HSA-69002
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Host Interactions of HIV factors R-HSA-162909
Stabilization of p53 R-HSA-69541
Cellular response to chemical stress R-HSA-9711123
Metabolism of RNA R-HSA-8953854
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Deubiquitination R-HSA-5688426
Infectious disease R-HSA-5663205
FCERI mediated NF-kB activation R-HSA-2871837
KEAP1-NFE2L2 pathway R-HSA-9755511
Ub-specific processing proteases R-HSA-5689880
DNA Double-Strand Break Repair R-HSA-5693532
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
Cellular responses to stress R-HSA-2262752
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Post-translational protein modification R-HSA-597592
CLEC7A (Dectin-1) signaling R-HSA-5607764
Orc1 removal from chromatin R-HSA-68949
Homology Directed Repair R-HSA-5693538
PCP/CE pathway R-HSA-4086400
Vpu mediated degradation of CD4 R-HSA-180534
Class I MHC mediated antigen processing & presentation R-HSA-983169
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Immune System R-HSA-168256
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of DVL R-HSA-4641258
Degradation of AXIN R-HSA-4641257
Downstream TCR signaling R-HSA-202424
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Developmental Biology R-HSA-1266738
Signaling by WNT R-HSA-195721
M Phase R-HSA-68886
Mitotic G2-G2/M phases R-HSA-453274
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Generic Transcription Pathway R-HSA-212436
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
Hh mutants are degraded by ERAD R-HSA-5362768
Hedgehog 'on' state R-HSA-5632684
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
Resolution of D-Loop Structures R-HSA-5693537
Axon guidance R-HSA-422475
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle, Mitotic R-HSA-69278
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK family signaling cascades R-HSA-5683057
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Intracellular signaling by second messengers R-HSA-9006925
G2/M Checkpoints R-HSA-69481
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic Anaphase R-HSA-68882
p53-Independent DNA Damage Response R-HSA-69610
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Programmed Cell Death R-HSA-5357801
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Transcriptional regulation by RUNX3 R-HSA-8878159
DNA Repair R-HSA-73894
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of RUNX3 expression and activity R-HSA-8941858
Signal Transduction R-HSA-162582
G1/S Transition R-HSA-69206
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Switching of origins to a post-replicative state R-HSA-69052
ER-Phagosome pathway R-HSA-1236974
Antigen processing-Cross presentation R-HSA-1236975
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
NIK-->noncanonical NF-kB signaling R-HSA-5676590
PIP3 activates AKT signaling R-HSA-1257604
Regulation of Apoptosis R-HSA-169911
Metabolism of proteins R-HSA-392499
Signaling by Hedgehog R-HSA-5358351
S Phase R-HSA-69242
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Metabolism of polyamines R-HSA-351202
Diseases of DNA repair R-HSA-9675135
Cyclin E associated events during G1/S transition R-HSA-69202
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
DNA Replication R-HSA-69306
MAPK6/MAPK4 signaling R-HSA-5687128
MAPK1/MAPK3 signaling R-HSA-5684996
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Neddylation R-HSA-8951664
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
TCR signaling R-HSA-202403
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mitotic cell cycle R-HSA-453276
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by ROBO receptors R-HSA-376176
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RAF/MAP kinase cascade R-HSA-5673001
Regulation of RAS by GAPs R-HSA-5658442
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
Hedgehog 'off' state R-HSA-5610787
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Negative regulation of NOTCH4 signaling R-HSA-9604323
HDR through Homologous Recombination (HRR) R-HSA-5685942
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
Cell Cycle R-HSA-1640170
ABC-family proteins mediated transport R-HSA-382556
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Adaptive Immune System R-HSA-1280218
Hedgehog ligand biogenesis R-HSA-5358346
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic Metaphase and Anaphase R-HSA-2555396
G2/M Checkpoints R-HSA-69481
PTEN Regulation R-HSA-6807070
Mitotic G2-G2/M phases R-HSA-453274
Separation of Sister Chromatids R-HSA-2467813
Hedgehog 'off' state R-HSA-5610787
Regulation of PTEN stability and activity R-HSA-8948751
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Innate Immune System R-HSA-168249
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Degradation of AXIN R-HSA-4641257
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by NOTCH4 R-HSA-9013694
MAPK family signaling cascades R-HSA-5683057
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S Transition R-HSA-69206
Nuclear events mediated by NFE2L2 R-HSA-9759194
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ub-specific processing proteases R-HSA-5689880
PIP3 activates AKT signaling R-HSA-1257604
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stress R-HSA-2262752
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 signaling R-HSA-9020702
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Transport of small molecules R-HSA-382551
Regulation of Apoptosis R-HSA-169911
Signaling by Interleukins R-HSA-449147
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of beta-catenin by the destruction complex R-HSA-195253
Negative regulation of NOTCH4 signaling R-HSA-9604323
MAPK6/MAPK4 signaling R-HSA-5687128
Axon guidance R-HSA-422475
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Impaired BRCA2 binding to RAD51 R-HSA-9709570
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI1 by the proteasome R-HSA-5610780
Nervous system development R-HSA-9675108
Cellular response to chemical stress R-HSA-9711123
S Phase R-HSA-69242
Hedgehog 'on' state R-HSA-5632684
Class I MHC mediated antigen processing & presentation R-HSA-983169
Signaling by NOTCH R-HSA-157118
ABC transporter disorders R-HSA-5619084
Synthesis of DNA R-HSA-69239
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Stabilization of p53 R-HSA-69541
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Metabolism of RNA R-HSA-8953854
Downstream TCR signaling R-HSA-202424
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX3 R-HSA-8878159
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RAF/MAP kinase cascade R-HSA-5673001
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by ROBO receptors R-HSA-376176
Programmed Cell Death R-HSA-5357801
Regulation of RAS by GAPs R-HSA-5658442
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK1/MAPK3 signaling R-HSA-5684996
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to hypoxia R-HSA-1234174
HIV Infection R-HSA-162906
CLEC7A (Dectin-1) signaling R-HSA-5607764
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
DNA Double-Strand Break Repair R-HSA-5693532
Deubiquitination R-HSA-5688426
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Defective CFTR causes cystic fibrosis R-HSA-5678895
Adaptive Immune System R-HSA-1280218
Resolution of D-Loop Structures R-HSA-5693537
Regulation of mitotic cell cycle R-HSA-453276
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Degradation of DVL R-HSA-4641258
Disorders of transmembrane transporters R-HSA-5619115
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX2 R-HSA-8878166
Generic Transcription Pathway R-HSA-212436
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Asymmetric localization of PCP proteins R-HSA-4608870
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
DNA Replication R-HSA-69306
Orc1 removal from chromatin R-HSA-68949
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
FCERI mediated NF-kB activation R-HSA-2871837
HDR through Homologous Recombination (HRR) R-HSA-5685942
TCF dependent signaling in response to WNT R-HSA-201681
Vif-mediated degradation of APOBEC3G R-HSA-180585
DNA Replication Pre-Initiation R-HSA-69002
Host Interactions of HIV factors R-HSA-162909
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
PCP/CE pathway R-HSA-4086400
Hh mutants abrogate ligand secretion R-HSA-5387390
M Phase R-HSA-68886
Diseases of DNA repair R-HSA-9675135
Regulation of RUNX2 expression and activity R-HSA-8939902
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of polyamines R-HSA-351202
Cytokine Signaling in Immune system R-HSA-1280215
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of amino acids and derivatives R-HSA-71291
Hh mutants are degraded by ERAD R-HSA-5362768
Apoptosis R-HSA-109581
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle Checkpoints R-HSA-69620
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
C-type lectin receptors (CLRs) R-HSA-5621481
Neddylation R-HSA-8951664
Cell Cycle, Mitotic R-HSA-69278
TCR signaling R-HSA-202403
Infectious disease R-HSA-5663205
NIK-->noncanonical NF-kB signaling R-HSA-5676590
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism R-HSA-1430728
Mitotic Anaphase R-HSA-68882
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
ER-Phagosome pathway R-HSA-1236974
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX1 R-HSA-8878171
DNA Repair R-HSA-73894
Metabolism of proteins R-HSA-392499
Signaling by WNT R-HSA-195721
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Hedgehog R-HSA-5358351
Post-translational protein modification R-HSA-597592
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RNA Polymerase II Transcription R-HSA-73857
Assembly of the pre-replicative complex R-HSA-68867
Switching of origins to a post-replicative state R-HSA-69052
Homology Directed Repair R-HSA-5693538
Cyclin E associated events during G1/S transition R-HSA-69202
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Disease R-HSA-1643685
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle R-HSA-1640170
Nervous system development R-HSA-9675108
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Diseases of DNA repair R-HSA-9675135
Separation of Sister Chromatids R-HSA-2467813
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G2/M Checkpoints R-HSA-69481
Impaired BRCA2 binding to RAD51 R-HSA-9709570
ER-Phagosome pathway R-HSA-1236974
Degradation of beta-catenin by the destruction complex R-HSA-195253
Disorders of transmembrane transporters R-HSA-5619115
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Deubiquitination R-HSA-5688426
HDR through Homologous Recombination (HRR) R-HSA-5685942
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Cell Cycle Checkpoints R-HSA-69620
Signaling by WNT R-HSA-195721
M Phase R-HSA-68886
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic Metaphase and Anaphase R-HSA-2555396
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Intracellular signaling by second messengers R-HSA-9006925
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Host Interactions of HIV factors R-HSA-162909
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of proteins R-HSA-392499
Resolution of D-Loop Structures R-HSA-5693537
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G2-G2/M phases R-HSA-453274
Asymmetric localization of PCP proteins R-HSA-4608870
PTEN Regulation R-HSA-6807070
Generic Transcription Pathway R-HSA-212436
Degradation of GLI1 by the proteasome R-HSA-5610780
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vpu mediated degradation of CD4 R-HSA-180534
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of Apoptosis R-HSA-169911
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Downstream TCR signaling R-HSA-202424
Cellular response to hypoxia R-HSA-1234174
Cell Cycle, Mitotic R-HSA-69278
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to chemical stress R-HSA-9711123
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Anaphase R-HSA-68882
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
UCH proteinases R-HSA-5689603
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog 'off' state R-HSA-5610787
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of mitotic cell cycle R-HSA-453276
DNA Replication R-HSA-69306
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of amino acids and derivatives R-HSA-71291
ABC transporter disorders R-HSA-5619084
G2/M Transition R-HSA-69275
Metabolism of polyamines R-HSA-351202
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of DVL R-HSA-4641258
p53-Independent DNA Damage Response R-HSA-69610
Programmed Cell Death R-HSA-5357801
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stress R-HSA-2262752
NIK-->noncanonical NF-kB signaling R-HSA-5676590
S Phase R-HSA-69242
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cytokine Signaling in Immune system R-HSA-1280215
ABC-family proteins mediated transport R-HSA-382556
Metabolism R-HSA-1430728
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Signaling by Hedgehog R-HSA-5358351
Innate Immune System R-HSA-168249
Gene expression (Transcription) R-HSA-74160
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Assembly of the pre-replicative complex R-HSA-68867
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
HIV Infection R-HSA-162906
Degradation of AXIN R-HSA-4641257
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Repair R-HSA-73894
PCP/CE pathway R-HSA-4086400
Cellular responses to stimuli R-HSA-8953897
Class I MHC mediated antigen processing & presentation R-HSA-983169
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX3 expression and activity R-HSA-8941858
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Interleukins R-HSA-449147
Homology Directed Repair R-HSA-5693538
Disease R-HSA-1643685
TCR signaling R-HSA-202403
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
DNA Double-Strand Break Repair R-HSA-5693532
Hh mutants abrogate ligand secretion R-HSA-5387390
Transcriptional regulation by RUNX1 R-HSA-8878171
Transcriptional regulation by RUNX2 R-HSA-8878166
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Orc1 removal from chromatin R-HSA-68949
Adaptive Immune System R-HSA-1280218
Negative regulation of NOTCH4 signaling R-HSA-9604323
PIP3 activates AKT signaling R-HSA-1257604
Stabilization of p53 R-HSA-69541
Metabolism of RNA R-HSA-8953854
Apoptosis R-HSA-109581
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Transport of small molecules R-HSA-382551
Post-translational protein modification R-HSA-597592
DNA Replication Pre-Initiation R-HSA-69002
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Neddylation R-HSA-8951664
FCERI mediated NF-kB activation R-HSA-2871837
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Interleukin-1 signaling R-HSA-9020702
G1/S DNA Damage Checkpoints R-HSA-69615
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hh mutants are degraded by ERAD R-HSA-5362768
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by NOTCH4 R-HSA-9013694
Nuclear events mediated by NFE2L2 R-HSA-9759194
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of polyamines R-HSA-351202
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle R-HSA-1640170
Vif-mediated degradation of APOBEC3G R-HSA-180585
Post-translational protein modification R-HSA-597592
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Host Interactions of HIV factors R-HSA-162909
Cell Cycle Checkpoints R-HSA-69620
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transcriptional regulation by RUNX1 R-HSA-8878171
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transport of small molecules R-HSA-382551
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of proteins R-HSA-392499
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX3 R-HSA-8878159
Generic Transcription Pathway R-HSA-212436
PCP/CE pathway R-HSA-4086400
Cyclin E associated events during G1/S transition R-HSA-69202
Defective CFTR causes cystic fibrosis R-HSA-5678895
Apoptosis R-HSA-109581
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Resolution of D-Loop Structures R-HSA-5693537
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Orc1 removal from chromatin R-HSA-68949
Regulation of mitotic cell cycle R-HSA-453276
Innate Immune System R-HSA-168249
MAPK6/MAPK4 signaling R-HSA-5687128
Negative regulation of NOTCH4 signaling R-HSA-9604323
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Assembly of the pre-replicative complex R-HSA-68867
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular response to chemical stress R-HSA-9711123
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of DVL R-HSA-4641258
Antigen processing-Cross presentation R-HSA-1236975
HDR through Homologous Recombination (HRR) R-HSA-5685942
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by Interleukins R-HSA-449147
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
PTEN Regulation R-HSA-6807070
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
UCH proteinases R-HSA-5689603
G1/S Transition R-HSA-69206
Regulation of Apoptosis R-HSA-169911
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
DNA Replication R-HSA-69306
RNA Polymerase II Transcription R-HSA-73857
G1/S DNA Damage Checkpoints R-HSA-69615
Deubiquitination R-HSA-5688426
Intracellular signaling by second messengers R-HSA-9006925
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of PTEN stability and activity R-HSA-8948751
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Regulation of RUNX2 expression and activity R-HSA-8939902
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cellular responses to stress R-HSA-2262752
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Immune System R-HSA-168256
HIV Infection R-HSA-162906
Cell Cycle, Mitotic R-HSA-69278
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
DNA Double-Strand Break Repair R-HSA-5693532
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Interleukin-1 signaling R-HSA-9020702
MAPK family signaling cascades R-HSA-5683057
Adaptive Immune System R-HSA-1280218
Mitotic G1 phase and G1/S transition R-HSA-453279
Ub-specific processing proteases R-HSA-5689880
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RUNX3 expression and activity R-HSA-8941858
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
Mitotic Anaphase R-HSA-68882
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
Beta-catenin independent WNT signaling R-HSA-3858494
DNA Replication Pre-Initiation R-HSA-69002
Diseases of DNA repair R-HSA-9675135
Signaling by ROBO receptors R-HSA-376176
Cellular response to hypoxia R-HSA-1234174
Vpu mediated degradation of CD4 R-HSA-180534
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Homology Directed Repair R-HSA-5693538
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
FCERI mediated NF-kB activation R-HSA-2871837
ER-Phagosome pathway R-HSA-1236974
Degradation of AXIN R-HSA-4641257
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
Mitotic Metaphase and Anaphase R-HSA-2555396
S Phase R-HSA-69242
Class I MHC mediated antigen processing & presentation R-HSA-983169
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
DNA Repair R-HSA-73894
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by NOTCH4 R-HSA-9013694
Hedgehog 'off' state R-HSA-5610787
Downstream TCR signaling R-HSA-202424
Gene expression (Transcription) R-HSA-74160
ABC-family proteins mediated transport R-HSA-382556
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Nervous system development R-HSA-9675108
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CLEC7A (Dectin-1) signaling R-HSA-5607764
Stabilization of p53 R-HSA-69541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G2-G2/M phases R-HSA-453274
Signaling by WNT R-HSA-195721
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 family signaling R-HSA-446652
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism R-HSA-1430728
M Phase R-HSA-68886
G2/M Transition R-HSA-69275
Signaling by Hedgehog R-HSA-5358351
Axon guidance R-HSA-422475
Synthesis of DNA R-HSA-69239
ABC transporter disorders R-HSA-5619084
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of RNA R-HSA-8953854
Switching of origins to a post-replicative state R-HSA-69052
Signal Transduction R-HSA-162582
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI2 by the proteasome R-HSA-5610783
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Programmed Cell Death R-HSA-5357801
DNA Repair R-HSA-73894
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Apoptosis R-HSA-109581
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Post-translational protein modification R-HSA-597592
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of PTEN stability and activity R-HSA-8948751
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular responses to stimuli R-HSA-8953897
Hh mutants abrogate ligand secretion R-HSA-5387390
Interleukin-1 signaling R-HSA-9020702
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
M Phase R-HSA-68886
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RAS by GAPs R-HSA-5658442
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Deubiquitination R-HSA-5688426
ER-Phagosome pathway R-HSA-1236974
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vpu mediated degradation of CD4 R-HSA-180534
Cellular response to hypoxia R-HSA-1234174
MAPK1/MAPK3 signaling R-HSA-5684996
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Signaling by Interleukins R-HSA-449147
Degradation of AXIN R-HSA-4641257
Axon guidance R-HSA-422475
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Regulation of RUNX2 expression and activity R-HSA-8939902
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell Cycle R-HSA-1640170
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX1 R-HSA-8878171
Transport of small molecules R-HSA-382551
Mitotic G2-G2/M phases R-HSA-453274
Diseases of DNA repair R-HSA-9675135
Infectious disease R-HSA-5663205
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Transcriptional regulation by RUNX3 R-HSA-8878159
Developmental Biology R-HSA-1266738
Cellular response to chemical stress R-HSA-9711123
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disorders of transmembrane transporters R-HSA-5619115
C-type lectin receptors (CLRs) R-HSA-5621481
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
TCR signaling R-HSA-202403
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Nuclear events mediated by NFE2L2 R-HSA-9759194
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
Switching of origins to a post-replicative state R-HSA-69052
S Phase R-HSA-69242
Metabolism of amino acids and derivatives R-HSA-71291
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog ligand biogenesis R-HSA-5358346
DNA Double-Strand Break Repair R-HSA-5693532
DNA Replication Pre-Initiation R-HSA-69002
NIK-->noncanonical NF-kB signaling R-HSA-5676590
HIV Infection R-HSA-162906
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Intracellular signaling by second messengers R-HSA-9006925
Downstream TCR signaling R-HSA-202424
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
Stabilization of p53 R-HSA-69541
p53-Independent DNA Damage Response R-HSA-69610
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
PTEN Regulation R-HSA-6807070
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Checkpoints R-HSA-69481
G2/M Transition R-HSA-69275
Mitotic G1 phase and G1/S transition R-HSA-453279
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
Assembly of the pre-replicative complex R-HSA-68867
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hh mutants are degraded by ERAD R-HSA-5362768
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Neddylation R-HSA-8951664
Degradation of DVL R-HSA-4641258
Host Interactions of HIV factors R-HSA-162909
Homology Directed Repair R-HSA-5693538
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Disease R-HSA-1643685
Interleukin-1 family signaling R-HSA-446652
Signaling by Hedgehog R-HSA-5358351
G1/S Transition R-HSA-69206
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Metabolism of proteins R-HSA-392499
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX3 expression and activity R-HSA-8941858
PCP/CE pathway R-HSA-4086400
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Adaptive Immune System R-HSA-1280218
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cyclin E associated events during G1/S transition R-HSA-69202
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
UCH proteinases R-HSA-5689603
Resolution of D-Loop Structures R-HSA-5693537
Signaling by ROBO receptors R-HSA-376176
Cell Cycle Checkpoints R-HSA-69620
Signaling by WNT R-HSA-195721
Cell Cycle, Mitotic R-HSA-69278
HDR through Homologous Recombination (HRR) R-HSA-5685942
Regulation of Apoptosis R-HSA-169911
Gene expression (Transcription) R-HSA-74160
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Asymmetric localization of PCP proteins R-HSA-4608870
KEAP1-NFE2L2 pathway R-HSA-9755511
Separation of Sister Chromatids R-HSA-2467813
Immune System R-HSA-168256
Metabolism of polyamines R-HSA-351202
ABC-family proteins mediated transport R-HSA-382556
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Beta-catenin independent WNT signaling R-HSA-3858494
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
FCERI mediated NF-kB activation R-HSA-2871837
Nervous system development R-HSA-9675108
Vif-mediated degradation of APOBEC3G R-HSA-180585
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Synthesis of DNA R-HSA-69239
PIP3 activates AKT signaling R-HSA-1257604
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
ABC transporter disorders R-HSA-5619084
RNA Polymerase II Transcription R-HSA-73857
Mitotic Anaphase R-HSA-68882
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by Interleukins R-HSA-449147
Regulation of RAS by GAPs R-HSA-5658442
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Metabolism of amino acids and derivatives R-HSA-71291
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Regulation of mitotic cell cycle R-HSA-453276
Disease R-HSA-1643685
Signaling by NOTCH R-HSA-157118
Cellular response to hypoxia R-HSA-1234174
DNA Replication Pre-Initiation R-HSA-69002
G1/S DNA Damage Checkpoints R-HSA-69615
Adaptive Immune System R-HSA-1280218
Generic Transcription Pathway R-HSA-212436
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Separation of Sister Chromatids R-HSA-2467813
RNA Polymerase II Transcription R-HSA-73857
Homology Directed Repair R-HSA-5693538
G2/M Transition R-HSA-69275
Vif-mediated degradation of APOBEC3G R-HSA-180585
Antigen processing-Cross presentation R-HSA-1236975
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 signaling R-HSA-9020702
DNA Double-Strand Break Repair R-HSA-5693532
Neddylation R-HSA-8951664
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Cellular responses to stimuli R-HSA-8953897
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Repair R-HSA-73894
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Cell Cycle Checkpoints R-HSA-69620
Ub-specific processing proteases R-HSA-5689880
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Gene expression (Transcription) R-HSA-74160
Synthesis of DNA R-HSA-69239
Degradation of GLI1 by the proteasome R-HSA-5610780
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ABC-family proteins mediated transport R-HSA-382556
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of RNA R-HSA-8953854
Resolution of D-Loop Structures R-HSA-5693537
Signaling by NOTCH4 R-HSA-9013694
Regulation of PTEN stability and activity R-HSA-8948751
MAPK family signaling cascades R-HSA-5683057
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S Transition R-HSA-69206
Hh mutants abrogate ligand secretion R-HSA-5387390
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Switching of origins to a post-replicative state R-HSA-69052
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream TCR signaling R-HSA-202424
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Transport of small molecules R-HSA-382551
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Host Interactions of HIV factors R-HSA-162909
Mitotic G2-G2/M phases R-HSA-453274
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX2 R-HSA-8878166
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
ABC transporter disorders R-HSA-5619084
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Cytokine Signaling in Immune system R-HSA-1280215
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism R-HSA-1430728
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Diseases of DNA repair R-HSA-9675135
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
S Phase R-HSA-69242
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Mitotic G1 phase and G1/S transition R-HSA-453279
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cell Cycle, Mitotic R-HSA-69278
Assembly of the pre-replicative complex R-HSA-68867
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disorders of transmembrane transporters R-HSA-5619115
Apoptosis R-HSA-109581
Degradation of DVL R-HSA-4641258
Orc1 removal from chromatin R-HSA-68949
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog ligand biogenesis R-HSA-5358346
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of proteins R-HSA-392499
Cyclin E associated events during G1/S transition R-HSA-69202
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular responses to stress R-HSA-2262752
Signaling by Hedgehog R-HSA-5358351
Mitotic Metaphase and Anaphase R-HSA-2555396
Programmed Cell Death R-HSA-5357801
Axon guidance R-HSA-422475
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Post-translational protein modification R-HSA-597592
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by the B Cell Receptor (BCR) R-HSA-983705
M Phase R-HSA-68886
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
CLEC7A (Dectin-1) signaling R-HSA-5607764
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
UCH proteinases R-HSA-5689603
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of AXIN R-HSA-4641257
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX1 R-HSA-8878171
HIV Infection R-HSA-162906
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
HDR through Homologous Recombination (HRR) R-HSA-5685942
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
KEAP1-NFE2L2 pathway R-HSA-9755511
PCP/CE pathway R-HSA-4086400
Stabilization of p53 R-HSA-69541
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX3 R-HSA-8878159
Developmental Biology R-HSA-1266738
Hedgehog 'off' state R-HSA-5610787
DNA Replication R-HSA-69306
Hh mutants are degraded by ERAD R-HSA-5362768
Signal Transduction R-HSA-162582
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
ER-Phagosome pathway R-HSA-1236974
Signaling by ROBO receptors R-HSA-376176
Negative regulation of NOTCH4 signaling R-HSA-9604323
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
TCF dependent signaling in response to WNT R-HSA-201681
Vpu mediated degradation of CD4 R-HSA-180534
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle R-HSA-1640170
Nervous system development R-HSA-9675108
Infectious disease R-HSA-5663205
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652

Expression Atlas ENSG00000127922
NCBI gene (formerly Entrezgene) 7979
GeneCards 10845
HGNC Symbol HGNC:10845
MIM gene 601285
UniProtKB Gene Name Q6ZVN7
WikiGene 7979
Gene: PSMB2
Ensembl ID : ENSG00000126067
Description: proteasome 20S subunit beta 2
Gene Synonyms: HC7-I
6 APIs:
218 Possible Orthologues:

G1/S Transition R-HSA-69206
Signaling by NOTCH R-HSA-157118
PIP3 activates AKT signaling R-HSA-1257604
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog 'off' state R-HSA-5610787
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of PTEN stability and activity R-HSA-8948751
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PCP/CE pathway R-HSA-4086400
Neddylation R-HSA-8951664
Transport of small molecules R-HSA-382551
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle Checkpoints R-HSA-69620
HIV Infection R-HSA-162906
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of RNA R-HSA-8953854
MAPK1/MAPK3 signaling R-HSA-5684996
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signal Transduction R-HSA-162582
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by NOTCH R-HSA-157118
Degradation of GLI2 by the proteasome R-HSA-5610783
Separation of Sister Chromatids R-HSA-2467813
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Apoptosis R-HSA-109581
Activation of NF-kappaB in B cells R-HSA-1169091
DNA Replication R-HSA-69306
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Host Interactions of HIV factors R-HSA-162909
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
Innate Immune System R-HSA-168249
Antigen processing-Cross presentation R-HSA-1236975
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of proteins R-HSA-392499
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX1 R-HSA-8878171
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
Downstream TCR signaling R-HSA-202424
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RAF/MAP kinase cascade R-HSA-5673001
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
Assembly of the pre-replicative complex R-HSA-68867
Signaling by Interleukins R-HSA-449147
Metabolism of polyamines R-HSA-351202
Metabolism R-HSA-1430728
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK family signaling cascades R-HSA-5683057
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by WNT R-HSA-195721
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PTEN Regulation R-HSA-6807070
FCERI mediated NF-kB activation R-HSA-2871837
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
CLEC7A (Dectin-1) signaling R-HSA-5607764
UCH proteinases R-HSA-5689603
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of RAS by GAPs R-HSA-5658442
TCR signaling R-HSA-202403
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G2-G2/M phases R-HSA-453274
ABC transporter disorders R-HSA-5619084
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Orc1 removal from chromatin R-HSA-68949
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular response to chemical stress R-HSA-9711123
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RUNX2 expression and activity R-HSA-8939902
Immune System R-HSA-168256
M Phase R-HSA-68886
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G2/M Checkpoints R-HSA-69481
Adaptive Immune System R-HSA-1280218
Gene expression (Transcription) R-HSA-74160
Disorders of transmembrane transporters R-HSA-5619115
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cyclin E associated events during G1/S transition R-HSA-69202
Synthesis of DNA R-HSA-69239
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of AXIN R-HSA-4641257
Mitotic Metaphase and Anaphase R-HSA-2555396
Beta-catenin independent WNT signaling R-HSA-3858494
Disease R-HSA-1643685
Stabilization of p53 R-HSA-69541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle, Mitotic R-HSA-69278
Mitotic G1 phase and G1/S transition R-HSA-453279
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'on' state R-HSA-5632684
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Hedgehog R-HSA-5358351
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 signaling R-HSA-9020702
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of beta-catenin by the destruction complex R-HSA-195253
Negative regulation of NOTCH4 signaling R-HSA-9604323
Interleukin-1 family signaling R-HSA-446652
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Deubiquitination R-HSA-5688426
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent DNA Damage Response R-HSA-69610
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
Infectious disease R-HSA-5663205
DNA Replication Pre-Initiation R-HSA-69002
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle R-HSA-1640170
G1/S DNA Damage Checkpoints R-HSA-69615
Programmed Cell Death R-HSA-5357801
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of Apoptosis R-HSA-169911
Developmental Biology R-HSA-1266738
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
G1/S Transition R-HSA-69206
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic Anaphase R-HSA-68882
Infectious disease R-HSA-5663205
Cell Cycle Checkpoints R-HSA-69620
Neddylation R-HSA-8951664
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 family signaling R-HSA-446652
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of proteins R-HSA-392499
Apoptosis R-HSA-109581
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
Antigen processing-Cross presentation R-HSA-1236975
UCH proteinases R-HSA-5689603
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disease R-HSA-1643685
p53-Independent DNA Damage Response R-HSA-69610
Regulation of expression of SLITs and ROBOs R-HSA-9010553
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RAS by GAPs R-HSA-5658442
Signaling by WNT R-HSA-195721
Hh mutants abrogate ligand secretion R-HSA-5387390
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cytokine Signaling in Immune system R-HSA-1280215
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Innate Immune System R-HSA-168249
Intracellular signaling by second messengers R-HSA-9006925
DNA Replication R-HSA-69306
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH4 R-HSA-9013694
Regulation of mitotic cell cycle R-HSA-453276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Deubiquitination R-HSA-5688426
MAPK6/MAPK4 signaling R-HSA-5687128
Cell Cycle, Mitotic R-HSA-69278
Separation of Sister Chromatids R-HSA-2467813
Disorders of transmembrane transporters R-HSA-5619115
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of GLI1 by the proteasome R-HSA-5610780
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism of RNA R-HSA-8953854
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Beta-catenin independent WNT signaling R-HSA-3858494
Programmed Cell Death R-HSA-5357801
ABC-family proteins mediated transport R-HSA-382556
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ub-specific processing proteases R-HSA-5689880
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Developmental Biology R-HSA-1266738
Metabolism of polyamines R-HSA-351202
ER-Phagosome pathway R-HSA-1236974
Cellular response to chemical stress R-HSA-9711123
Activation of NF-kappaB in B cells R-HSA-1169091
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Interleukins R-HSA-449147
DNA Replication Pre-Initiation R-HSA-69002
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle R-HSA-1640170
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PCP/CE pathway R-HSA-4086400
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
Signal Transduction R-HSA-162582
Metabolism of amino acids and derivatives R-HSA-71291
Gene expression (Transcription) R-HSA-74160
Hedgehog 'on' state R-HSA-5632684
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular responses to stimuli R-HSA-8953897
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transport of small molecules R-HSA-382551
TCR signaling R-HSA-202403
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX3 expression and activity R-HSA-8941858
RAF/MAP kinase cascade R-HSA-5673001
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism R-HSA-1430728
Host Interactions of HIV factors R-HSA-162909
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Immune System R-HSA-168256
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Axon guidance R-HSA-422475
G1/S DNA Damage Checkpoints R-HSA-69615
Post-translational protein modification R-HSA-597592
HIV Infection R-HSA-162906
Cyclin E associated events during G1/S transition R-HSA-69202
S Phase R-HSA-69242
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Checkpoints R-HSA-69481
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of Apoptosis R-HSA-169911
Cellular responses to stress R-HSA-2262752
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
C-type lectin receptors (CLRs) R-HSA-5621481
PTEN Regulation R-HSA-6807070
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of AXIN R-HSA-4641257
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
CLEC7A (Dectin-1) signaling R-HSA-5607764
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Nervous system development R-HSA-9675108
G1/S Transition R-HSA-69206
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Synthesis of DNA R-HSA-69239
Class I MHC mediated antigen processing & presentation R-HSA-983169
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Generic Transcription Pathway R-HSA-212436
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of DVL R-HSA-4641258
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX2 R-HSA-8878166
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
Activation of NF-kappaB in B cells R-HSA-1169091
Synthesis of DNA R-HSA-69239
Regulation of Apoptosis R-HSA-169911
Hedgehog 'off' state R-HSA-5610787
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
Regulation of RAS by GAPs R-HSA-5658442
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 family signaling R-HSA-446652
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Interleukins R-HSA-449147
Nuclear events mediated by NFE2L2 R-HSA-9759194
Intracellular signaling by second messengers R-HSA-9006925
Vpu mediated degradation of CD4 R-HSA-180534
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ABC-family proteins mediated transport R-HSA-382556
G2/M Checkpoints R-HSA-69481
Transport of small molecules R-HSA-382551
Host Interactions of HIV factors R-HSA-162909
Cellular response to chemical stress R-HSA-9711123
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX2 R-HSA-8878166
Disorders of transmembrane transporters R-HSA-5619115
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of DVL R-HSA-4641258
Immune System R-HSA-168256
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by NOTCH R-HSA-157118
TCR signaling R-HSA-202403
Neddylation R-HSA-8951664
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Programmed Cell Death R-HSA-5357801
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Beta-catenin independent WNT signaling R-HSA-3858494
Cell Cycle, Mitotic R-HSA-69278
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX1 R-HSA-8878171
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
HIV Infection R-HSA-162906
RAF/MAP kinase cascade R-HSA-5673001
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
DNA Replication R-HSA-69306
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Separation of Sister Chromatids R-HSA-2467813
DNA Replication Pre-Initiation R-HSA-69002
Antigen processing-Cross presentation R-HSA-1236975
MAPK family signaling cascades R-HSA-5683057
Metabolism of polyamines R-HSA-351202
Defective CFTR causes cystic fibrosis R-HSA-5678895
KEAP1-NFE2L2 pathway R-HSA-9755511
ER-Phagosome pathway R-HSA-1236974
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by WNT R-HSA-195721
Gene expression (Transcription) R-HSA-74160
Class I MHC mediated antigen processing & presentation R-HSA-983169
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PIP3 activates AKT signaling R-HSA-1257604
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to hypoxia R-HSA-1234174
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Hedgehog R-HSA-5358351
Metabolism of RNA R-HSA-8953854
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of GLI2 by the proteasome R-HSA-5610783
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ub-specific processing proteases R-HSA-5689880
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of amino acids and derivatives R-HSA-71291
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Switching of origins to a post-replicative state R-HSA-69052
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by ROBO receptors R-HSA-376176
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of AXIN R-HSA-4641257
Innate Immune System R-HSA-168249
Downstream TCR signaling R-HSA-202424
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signal Transduction R-HSA-162582
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Anaphase R-HSA-68882
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
p53-Independent DNA Damage Response R-HSA-69610
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism R-HSA-1430728
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog 'on' state R-HSA-5632684
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Transition R-HSA-69275
Cytokine Signaling in Immune system R-HSA-1280215
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH4 R-HSA-9013694
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cell Cycle Checkpoints R-HSA-69620
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Metaphase and Anaphase R-HSA-2555396
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of GLI1 by the proteasome R-HSA-5610780
C-type lectin receptors (CLRs) R-HSA-5621481
Synthesis of DNA R-HSA-69239
Cellular response to hypoxia R-HSA-1234174
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular responses to stress R-HSA-2262752
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK family signaling cascades R-HSA-5683057
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI2 by the proteasome R-HSA-5610783
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
PCP/CE pathway R-HSA-4086400
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cyclin E associated events during G1/S transition R-HSA-69202
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Signal Transduction R-HSA-162582
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Interleukin-1 family signaling R-HSA-446652
Degradation of GLI1 by the proteasome R-HSA-5610780
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stimuli R-HSA-8953897
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
KEAP1-NFE2L2 pathway R-HSA-9755511
Ub-specific processing proteases R-HSA-5689880
p53-Independent DNA Damage Response R-HSA-69610
Disease R-HSA-1643685
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Downstream TCR signaling R-HSA-202424
ER-Phagosome pathway R-HSA-1236974
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Infectious disease R-HSA-5663205
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by ROBO receptors R-HSA-376176
ABC transporter disorders R-HSA-5619084
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transcriptional regulation by RUNX3 R-HSA-8878159
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Axon guidance R-HSA-422475
Beta-catenin independent WNT signaling R-HSA-3858494
Hh mutants are degraded by ERAD R-HSA-5362768
PTEN Regulation R-HSA-6807070
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle, Mitotic R-HSA-69278
FCERI mediated NF-kB activation R-HSA-2871837
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Stabilization of p53 R-HSA-69541
Programmed Cell Death R-HSA-5357801
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Antigen processing-Cross presentation R-HSA-1236975
C-type lectin receptors (CLRs) R-HSA-5621481
Negative regulation of NOTCH4 signaling R-HSA-9604323
Mitotic Metaphase and Anaphase R-HSA-2555396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Nervous system development R-HSA-9675108
Switching of origins to a post-replicative state R-HSA-69052
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Regulation of RAS by GAPs R-HSA-5658442
G1/S Transition R-HSA-69206
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Interleukin-1 signaling R-HSA-9020702
Degradation of DVL R-HSA-4641258
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of polyamines R-HSA-351202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Generic Transcription Pathway R-HSA-212436
Mitotic Anaphase R-HSA-68882
G2/M Transition R-HSA-69275
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cell Cycle R-HSA-1640170
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Apoptosis R-HSA-109581
Regulation of mitotic cell cycle R-HSA-453276
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX1 R-HSA-8878171
HIV Infection R-HSA-162906
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
TCF dependent signaling in response to WNT R-HSA-201681
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G1/S DNA Damage Checkpoints R-HSA-69615
Disorders of transmembrane transporters R-HSA-5619115
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
Signaling by Hedgehog R-HSA-5358351
Metabolism of proteins R-HSA-392499
Mitotic G1 phase and G1/S transition R-HSA-453279
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Neddylation R-HSA-8951664
RAF/MAP kinase cascade R-HSA-5673001
RNA Polymerase II Transcription R-HSA-73857
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of amino acids and derivatives R-HSA-71291
DNA Replication Pre-Initiation R-HSA-69002
G2/M Checkpoints R-HSA-69481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK1/MAPK3 signaling R-HSA-5684996
Class I MHC mediated antigen processing & presentation R-HSA-983169
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of Apoptosis R-HSA-169911
M Phase R-HSA-68886
Signaling by WNT R-HSA-195721
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by Interleukins R-HSA-449147
Hedgehog 'off' state R-HSA-5610787
Metabolism of RNA R-HSA-8953854
Immune System R-HSA-168256
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transport of small molecules R-HSA-382551
Host Interactions of HIV factors R-HSA-162909
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX1 R-HSA-8878171
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Axon guidance R-HSA-422475
Degradation of GLI2 by the proteasome R-HSA-5610783
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Apoptosis R-HSA-109581
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ABC-family proteins mediated transport R-HSA-382556
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK1/MAPK3 signaling R-HSA-5684996
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX3 R-HSA-8878159
Immune System R-HSA-168256
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Separation of Sister Chromatids R-HSA-2467813
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism R-HSA-1430728
Stabilization of p53 R-HSA-69541
Deubiquitination R-HSA-5688426
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of Apoptosis R-HSA-169911
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
CLEC7A (Dectin-1) signaling R-HSA-5607764
Ub-specific processing proteases R-HSA-5689880
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ER-Phagosome pathway R-HSA-1236974
Synthesis of DNA R-HSA-69239
PCP/CE pathway R-HSA-4086400
Cell Cycle, Mitotic R-HSA-69278
Cellular response to hypoxia R-HSA-1234174
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
C-type lectin receptors (CLRs) R-HSA-5621481
Signal Transduction R-HSA-162582
HIV Infection R-HSA-162906
G2/M Checkpoints R-HSA-69481
Regulation of RUNX2 expression and activity R-HSA-8939902
Host Interactions of HIV factors R-HSA-162909
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Activation of NF-kappaB in B cells R-HSA-1169091
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nervous system development R-HSA-9675108
Metabolism of polyamines R-HSA-351202
Disorders of transmembrane transporters R-HSA-5619115
Signaling by WNT R-HSA-195721
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Disease R-HSA-1643685
Degradation of beta-catenin by the destruction complex R-HSA-195253
Assembly of the pre-replicative complex R-HSA-68867
Cyclin E associated events during G1/S transition R-HSA-69202
Interleukin-1 signaling R-HSA-9020702
Downstream TCR signaling R-HSA-202424
Infectious disease R-HSA-5663205
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of RNA R-HSA-8953854
Generic Transcription Pathway R-HSA-212436
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog 'on' state R-HSA-5632684
Programmed Cell Death R-HSA-5357801
Cellular responses to stress R-HSA-2262752
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cytokine Signaling in Immune system R-HSA-1280215
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Gene expression (Transcription) R-HSA-74160
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Anaphase R-HSA-68882
TCR signaling R-HSA-202403
MAPK family signaling cascades R-HSA-5683057
KEAP1-NFE2L2 pathway R-HSA-9755511
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
Transport of small molecules R-HSA-382551
Defective CFTR causes cystic fibrosis R-HSA-5678895
G1/S Transition R-HSA-69206
Hh mutants are degraded by ERAD R-HSA-5362768
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
DNA Replication R-HSA-69306
p53-Dependent G1 DNA Damage Response R-HSA-69563
Vpu mediated degradation of CD4 R-HSA-180534
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Metaphase and Anaphase R-HSA-2555396
Switching of origins to a post-replicative state R-HSA-69052
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Post-translational protein modification R-HSA-597592
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing-Cross presentation R-HSA-1236975
Developmental Biology R-HSA-1266738
Neddylation R-HSA-8951664
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
DNA Replication Pre-Initiation R-HSA-69002
ABC transporter disorders R-HSA-5619084
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle R-HSA-1640170
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI1 by the proteasome R-HSA-5610780
PIP3 activates AKT signaling R-HSA-1257604
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
S Phase R-HSA-69242
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G2/M Transition R-HSA-69275
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by ROBO receptors R-HSA-376176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stimuli R-HSA-8953897
Metabolism of proteins R-HSA-392499
Cellular response to chemical stress R-HSA-9711123
MAPK1/MAPK3 signaling R-HSA-5684996
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle, Mitotic R-HSA-69278
Intracellular signaling by second messengers R-HSA-9006925
G1/S Transition R-HSA-69206
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nervous system development R-HSA-9675108
Infectious disease R-HSA-5663205
Cell Cycle R-HSA-1640170
PCP/CE pathway R-HSA-4086400
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of PTEN stability and activity R-HSA-8948751
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog ligand biogenesis R-HSA-5358346
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle Checkpoints R-HSA-69620
Signaling by Hedgehog R-HSA-5358351
Apoptosis R-HSA-109581
DNA Replication Pre-Initiation R-HSA-69002
Metabolism R-HSA-1430728
Disorders of transmembrane transporters R-HSA-5619115
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
Metabolism of polyamines R-HSA-351202
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Independent DNA Damage Response R-HSA-69610
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Anaphase R-HSA-68882
Activation of NF-kappaB in B cells R-HSA-1169091
Separation of Sister Chromatids R-HSA-2467813
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FCERI mediated NF-kB activation R-HSA-2871837
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by WNT R-HSA-195721
Regulation of RUNX3 expression and activity R-HSA-8941858
Cytokine Signaling in Immune system R-HSA-1280215
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
UCH proteinases R-HSA-5689603
Synthesis of DNA R-HSA-69239
Deubiquitination R-HSA-5688426
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stress R-HSA-2262752
TCR signaling R-HSA-202403
HIV Infection R-HSA-162906
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
TCF dependent signaling in response to WNT R-HSA-201681
Neddylation R-HSA-8951664
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vpu mediated degradation of CD4 R-HSA-180534
Disease R-HSA-1643685
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 signaling R-HSA-9020702
Signaling by NOTCH4 R-HSA-9013694
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cyclin E associated events during G1/S transition R-HSA-69202
Defective CFTR causes cystic fibrosis R-HSA-5678895
M Phase R-HSA-68886
Metabolism of proteins R-HSA-392499
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX2 R-HSA-8878166
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog 'on' state R-HSA-5632684
Gene expression (Transcription) R-HSA-74160
Degradation of DVL R-HSA-4641258
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Asymmetric localization of PCP proteins R-HSA-4608870
Stabilization of p53 R-HSA-69541
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of amino acids and derivatives R-HSA-71291
ABC transporter disorders R-HSA-5619084
ABC-family proteins mediated transport R-HSA-382556
Adaptive Immune System R-HSA-1280218
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI2 by the proteasome R-HSA-5610783
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of RNA R-HSA-8953854
Mitotic G2-G2/M phases R-HSA-453274
Signaling by ROBO receptors R-HSA-376176
Regulation of RAS by GAPs R-HSA-5658442
Antigen processing-Cross presentation R-HSA-1236975
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Innate Immune System R-HSA-168249
Hedgehog 'off' state R-HSA-5610787
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ER-Phagosome pathway R-HSA-1236974
Signaling by Interleukins R-HSA-449147
RAF/MAP kinase cascade R-HSA-5673001
Class I MHC mediated antigen processing & presentation R-HSA-983169
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX3 R-HSA-8878159
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1 DNA Damage Response R-HSA-69563
G2/M Checkpoints R-HSA-69481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hh mutants are degraded by ERAD R-HSA-5362768
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of Apoptosis R-HSA-169911
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PIP3 activates AKT signaling R-HSA-1257604
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to chemical stress R-HSA-9711123
Post-translational protein modification R-HSA-597592
Signaling by NOTCH R-HSA-157118
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 family signaling R-HSA-446652
S Phase R-HSA-69242
Developmental Biology R-HSA-1266738
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Assembly of the pre-replicative complex R-HSA-68867
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
Transport of small molecules R-HSA-382551
Intracellular signaling by second messengers R-HSA-9006925
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
Infectious disease R-HSA-5663205
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Assembly of the pre-replicative complex R-HSA-68867
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
ABC-family proteins mediated transport R-HSA-382556
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by Interleukins R-HSA-449147
Signaling by WNT R-HSA-195721
Downstream TCR signaling R-HSA-202424
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Post-translational protein modification R-HSA-597592
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stimuli R-HSA-8953897
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
Interleukin-1 signaling R-HSA-9020702
Regulation of PTEN stability and activity R-HSA-8948751
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
CLEC7A (Dectin-1) signaling R-HSA-5607764
Host Interactions of HIV factors R-HSA-162909
S Phase R-HSA-69242
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RAS by GAPs R-HSA-5658442
Innate Immune System R-HSA-168249
PTEN Regulation R-HSA-6807070
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
Orc1 removal from chromatin R-HSA-68949
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by ROBO receptors R-HSA-376176
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX3 R-HSA-8878159
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent DNA Damage Response R-HSA-69610
Nervous system development R-HSA-9675108
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog 'off' state R-HSA-5610787
DNA Replication R-HSA-69306
UCH proteinases R-HSA-5689603
Separation of Sister Chromatids R-HSA-2467813
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic G2-G2/M phases R-HSA-453274
FCERI mediated NF-kB activation R-HSA-2871837
Cyclin E associated events during G1/S transition R-HSA-69202
Programmed Cell Death R-HSA-5357801
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Anaphase R-HSA-68882
Hh mutants abrogate ligand secretion R-HSA-5387390
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of RNA R-HSA-8953854
Regulation of Apoptosis R-HSA-169911
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PIP3 activates AKT signaling R-HSA-1257604
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle R-HSA-1640170
Cellular response to hypoxia R-HSA-1234174
Regulation of RUNX3 expression and activity R-HSA-8941858
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RUNX2 expression and activity R-HSA-8939902
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
Regulation of mitotic cell cycle R-HSA-453276
Synthesis of DNA R-HSA-69239
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of polyamines R-HSA-351202
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Deubiquitination R-HSA-5688426
ER-Phagosome pathway R-HSA-1236974
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Hedgehog 'on' state R-HSA-5632684
Ub-specific processing proteases R-HSA-5689880
Cellular responses to stress R-HSA-2262752
Disorders of transmembrane transporters R-HSA-5619115
Cell Cycle Checkpoints R-HSA-69620
G2/M Checkpoints R-HSA-69481
DNA Replication Pre-Initiation R-HSA-69002
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of proteins R-HSA-392499
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of AXIN R-HSA-4641257
Mitotic Metaphase and Anaphase R-HSA-2555396
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of DVL R-HSA-4641258
PCP/CE pathway R-HSA-4086400
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Transition R-HSA-69275
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism R-HSA-1430728
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
HIV Infection R-HSA-162906
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cell Cycle, Mitotic R-HSA-69278
Neddylation R-HSA-8951664
Generic Transcription Pathway R-HSA-212436
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional regulation by RUNX1 R-HSA-8878171
Apoptosis R-HSA-109581
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Hedgehog R-HSA-5358351
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Defective CFTR causes cystic fibrosis R-HSA-5678895
TCR signaling R-HSA-202403
Antigen processing-Cross presentation R-HSA-1236975
Adaptive Immune System R-HSA-1280218
Mitotic G1 phase and G1/S transition R-HSA-453279
Switching of origins to a post-replicative state R-HSA-69052
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
HIV Infection R-HSA-162906
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stress R-HSA-2262752
Separation of Sister Chromatids R-HSA-2467813
Metabolism of RNA R-HSA-8953854
PIP3 activates AKT signaling R-HSA-1257604
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
FCERI mediated NF-kB activation R-HSA-2871837
Innate Immune System R-HSA-168249
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cytokine Signaling in Immune system R-HSA-1280215
Axon guidance R-HSA-422475
DNA Replication R-HSA-69306
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by ROBO receptors R-HSA-376176
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Host Interactions of HIV factors R-HSA-162909
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Vpu mediated degradation of CD4 R-HSA-180534
Infectious disease R-HSA-5663205
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by WNT R-HSA-195721
Transport of small molecules R-HSA-382551
Signaling by Interleukins R-HSA-449147
Hh mutants abrogate ligand secretion R-HSA-5387390
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
Regulation of mitotic cell cycle R-HSA-453276
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cyclin E associated events during G1/S transition R-HSA-69202
ABC-family proteins mediated transport R-HSA-382556
Disease R-HSA-1643685
Apoptosis R-HSA-109581
Metabolism of polyamines R-HSA-351202
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of DVL R-HSA-4641258
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Programmed Cell Death R-HSA-5357801
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH4 R-HSA-9013694
Interleukin-1 family signaling R-HSA-446652
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Metabolism R-HSA-1430728
M Phase R-HSA-68886
S Phase R-HSA-69242
Beta-catenin independent WNT signaling R-HSA-3858494
Antigen processing-Cross presentation R-HSA-1236975
Cellular response to chemical stress R-HSA-9711123
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
Neddylation R-HSA-8951664
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle R-HSA-1640170
Regulation of PTEN stability and activity R-HSA-8948751
Nervous system development R-HSA-9675108
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transcriptional regulation by RUNX2 R-HSA-8878166
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
C-type lectin receptors (CLRs) R-HSA-5621481
Immune System R-HSA-168256
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of AXIN R-HSA-4641257
Signaling by Hedgehog R-HSA-5358351
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
Adaptive Immune System R-HSA-1280218
G2/M Transition R-HSA-69275
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of amino acids and derivatives R-HSA-71291
TCR signaling R-HSA-202403
G1/S Transition R-HSA-69206
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
DNA Replication Pre-Initiation R-HSA-69002
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Negative regulation of NOTCH4 signaling R-HSA-9604323
ER-Phagosome pathway R-HSA-1236974
ABC transporter disorders R-HSA-5619084
Hedgehog 'off' state R-HSA-5610787
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PCP/CE pathway R-HSA-4086400
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX1 R-HSA-8878171
TCF dependent signaling in response to WNT R-HSA-201681
PTEN Regulation R-HSA-6807070
G2/M Checkpoints R-HSA-69481
Activation of NF-kappaB in B cells R-HSA-1169091
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of Apoptosis R-HSA-169911
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI1 by the proteasome R-HSA-5610780
CLEC7A (Dectin-1) signaling R-HSA-5607764
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic G1 phase and G1/S transition R-HSA-453279
Assembly of the pre-replicative complex R-HSA-68867
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RAS by GAPs R-HSA-5658442
Hh mutants are degraded by ERAD R-HSA-5362768
Disorders of transmembrane transporters R-HSA-5619115
Developmental Biology R-HSA-1266738
Stabilization of p53 R-HSA-69541
Switching of origins to a post-replicative state R-HSA-69052
Ub-specific processing proteases R-HSA-5689880
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 signaling R-HSA-9020702
RAF/MAP kinase cascade R-HSA-5673001
Intracellular signaling by second messengers R-HSA-9006925
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disorders of transmembrane transporters R-HSA-5619115
Immune System R-HSA-168256
Cellular responses to stress R-HSA-2262752
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by ROBO receptors R-HSA-376176
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nuclear events mediated by NFE2L2 R-HSA-9759194
Infectious disease R-HSA-5663205
PCP/CE pathway R-HSA-4086400
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stimuli R-HSA-8953897
Apoptosis R-HSA-109581
Cellular response to hypoxia R-HSA-1234174
Regulation of RUNX3 expression and activity R-HSA-8941858
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCR signaling R-HSA-202403
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
ABC transporter disorders R-HSA-5619084
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of RNA R-HSA-8953854
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Dependent G1 DNA Damage Response R-HSA-69563
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle R-HSA-1640170
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G2-G2/M phases R-HSA-453274
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Mitotic Anaphase R-HSA-68882
Switching of origins to a post-replicative state R-HSA-69052
HIV Infection R-HSA-162906
RNA Polymerase II Transcription R-HSA-73857
DNA Replication Pre-Initiation R-HSA-69002
Signaling by Interleukins R-HSA-449147
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog 'on' state R-HSA-5632684
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 signaling R-HSA-9020702
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Programmed Cell Death R-HSA-5357801
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
MAPK6/MAPK4 signaling R-HSA-5687128
Neddylation R-HSA-8951664
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TCF dependent signaling in response to WNT R-HSA-201681
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX3 R-HSA-8878159
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Generic Transcription Pathway R-HSA-212436
Signaling by WNT R-HSA-195721
Antigen processing-Cross presentation R-HSA-1236975
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of GLI1 by the proteasome R-HSA-5610780
Ub-specific processing proteases R-HSA-5689880
PTEN Regulation R-HSA-6807070
G2/M Transition R-HSA-69275
S Phase R-HSA-69242
RAF/MAP kinase cascade R-HSA-5673001
Deubiquitination R-HSA-5688426
Degradation of DVL R-HSA-4641258
Axon guidance R-HSA-422475
UCH proteinases R-HSA-5689603
Orc1 removal from chromatin R-HSA-68949
Hedgehog 'off' state R-HSA-5610787
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S Transition R-HSA-69206
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Developmental Biology R-HSA-1266738
Metabolism of proteins R-HSA-392499
p53-Independent DNA Damage Response R-HSA-69610
M Phase R-HSA-68886
Metabolism of polyamines R-HSA-351202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH R-HSA-157118
Separation of Sister Chromatids R-HSA-2467813
Cell Cycle, Mitotic R-HSA-69278
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Vif-mediated degradation of APOBEC3G R-HSA-180585
Interleukin-1 family signaling R-HSA-446652
ER-Phagosome pathway R-HSA-1236974
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Innate Immune System R-HSA-168249
Vpu mediated degradation of CD4 R-HSA-180534
Assembly of the pre-replicative complex R-HSA-68867
G2/M Checkpoints R-HSA-69481
Intracellular signaling by second messengers R-HSA-9006925
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Stabilization of p53 R-HSA-69541
Signaling by NOTCH4 R-HSA-9013694
Cyclin E associated events during G1/S transition R-HSA-69202
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
DNA Replication R-HSA-69306
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by Hedgehog R-HSA-5358351
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Activation of NF-kappaB in B cells R-HSA-1169091
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle Checkpoints R-HSA-69620
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G2/M Checkpoints R-HSA-69481
Degradation of beta-catenin by the destruction complex R-HSA-195253
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing-Cross presentation R-HSA-1236975
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of polyamines R-HSA-351202
Signaling by NOTCH R-HSA-157118
Programmed Cell Death R-HSA-5357801
Apoptosis R-HSA-109581
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Stabilization of p53 R-HSA-69541
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Metaphase and Anaphase R-HSA-2555396
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
UCH proteinases R-HSA-5689603
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
M Phase R-HSA-68886
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
PCP/CE pathway R-HSA-4086400
Innate Immune System R-HSA-168249
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of Apoptosis R-HSA-169911
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Degradation of DVL R-HSA-4641258
G2/M Transition R-HSA-69275
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent DNA Damage Response R-HSA-69610
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Anaphase R-HSA-68882
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Nuclear events mediated by NFE2L2 R-HSA-9759194
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of proteins R-HSA-392499
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism R-HSA-1430728
Signaling by ROBO receptors R-HSA-376176
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Regulation of RAS by GAPs R-HSA-5658442
Generic Transcription Pathway R-HSA-212436
Vif-mediated degradation of APOBEC3G R-HSA-180585
G1/S DNA Damage Checkpoints R-HSA-69615
Deubiquitination R-HSA-5688426
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Negative regulation of NOTCH4 signaling R-HSA-9604323
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular response to hypoxia R-HSA-1234174
MAPK6/MAPK4 signaling R-HSA-5687128
Switching of origins to a post-replicative state R-HSA-69052
Signaling by WNT R-HSA-195721
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S Transition R-HSA-69206
Activation of NF-kappaB in B cells R-HSA-1169091
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stimuli R-HSA-8953897
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Interleukins R-HSA-449147
Ub-specific processing proteases R-HSA-5689880
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Hedgehog 'off' state R-HSA-5610787
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Orc1 removal from chromatin R-HSA-68949
KEAP1-NFE2L2 pathway R-HSA-9755511
Assembly of the pre-replicative complex R-HSA-68867
Axon guidance R-HSA-422475
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Immune System R-HSA-168256
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by NOTCH4 R-HSA-9013694
Degradation of GLI2 by the proteasome R-HSA-5610783
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cell Cycle R-HSA-1640170
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HIV Infection R-HSA-162906
Signaling by Hedgehog R-HSA-5358351
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
Hh mutants abrogate ligand secretion R-HSA-5387390
Signal Transduction R-HSA-162582
Cellular response to chemical stress R-HSA-9711123
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RUNX2 expression and activity R-HSA-8939902
Downstream TCR signaling R-HSA-202424
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of AXIN R-HSA-4641257
Separation of Sister Chromatids R-HSA-2467813
Disorders of transmembrane transporters R-HSA-5619115
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of RUNX3 expression and activity R-HSA-8941858
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of RNA R-HSA-8953854
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle R-HSA-1640170
DNA Replication R-HSA-69306
Transport of small molecules R-HSA-382551
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of polyamines R-HSA-351202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by WNT R-HSA-195721
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle, Mitotic R-HSA-69278
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Checkpoints R-HSA-69481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
Apoptosis R-HSA-109581
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
Innate Immune System R-HSA-168249
G1/S Transition R-HSA-69206
Metabolism of proteins R-HSA-392499
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Hh mutants are degraded by ERAD R-HSA-5362768
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
Signaling by the B Cell Receptor (BCR) R-HSA-983705
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK family signaling cascades R-HSA-5683057
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ER-Phagosome pathway R-HSA-1236974
Infectious disease R-HSA-5663205
PTEN Regulation R-HSA-6807070
ABC transporter disorders R-HSA-5619084
HIV Infection R-HSA-162906
PCP/CE pathway R-HSA-4086400
Orc1 removal from chromatin R-HSA-68949
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
M Phase R-HSA-68886
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism R-HSA-1430728
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX1 R-HSA-8878171
KEAP1-NFE2L2 pathway R-HSA-9755511
Switching of origins to a post-replicative state R-HSA-69052
Degradation of GLI1 by the proteasome R-HSA-5610780
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
TCR signaling R-HSA-202403
Regulation of PTEN stability and activity R-HSA-8948751
Cellular responses to stress R-HSA-2262752
G2/M Transition R-HSA-69275
Signal Transduction R-HSA-162582
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular response to chemical stress R-HSA-9711123
Host Interactions of HIV factors R-HSA-162909
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Assembly of the pre-replicative complex R-HSA-68867
RAF/MAP kinase cascade R-HSA-5673001
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of Apoptosis R-HSA-169911
Disorders of transmembrane transporters R-HSA-5619115
Stabilization of p53 R-HSA-69541
Hedgehog ligand biogenesis R-HSA-5358346
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by NOTCH R-HSA-157118
Intracellular signaling by second messengers R-HSA-9006925
Programmed Cell Death R-HSA-5357801
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
UCH proteinases R-HSA-5689603
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC-family proteins mediated transport R-HSA-382556
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 signaling R-HSA-9020702
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH4 R-HSA-9013694
Regulation of RAS by GAPs R-HSA-5658442
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vpu mediated degradation of CD4 R-HSA-180534
Gene expression (Transcription) R-HSA-74160
Ub-specific processing proteases R-HSA-5689880
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Anaphase R-HSA-68882
Degradation of AXIN R-HSA-4641257
Signaling by Interleukins R-HSA-449147
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX3 expression and activity R-HSA-8941858
Developmental Biology R-HSA-1266738
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK1/MAPK3 signaling R-HSA-5684996
FCERI mediated NF-kB activation R-HSA-2871837
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by ROBO receptors R-HSA-376176
Degradation of DVL R-HSA-4641258
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
p53-Independent DNA Damage Response R-HSA-69610
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK6/MAPK4 signaling R-HSA-5687128
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Generic Transcription Pathway R-HSA-212436
Synthesis of DNA R-HSA-69239
Deubiquitination R-HSA-5688426
Cellular responses to stimuli R-HSA-8953897
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Post-translational protein modification R-HSA-597592
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
Neddylation R-HSA-8951664
DNA Replication Pre-Initiation R-HSA-69002
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin E associated events during G1/S transition R-HSA-69202
Axon guidance R-HSA-422475
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Downstream TCR signaling R-HSA-202424
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Negative regulation of NOTCH4 signaling R-HSA-9604323

Expression Atlas ENSG00000126067
NCBI gene (formerly Entrezgene) 5690
GeneCards 9539
HGNC Symbol HGNC:9539
MIM gene 602175
UniProtKB Gene Name P49721
WikiGene 5690
Gene: PSMB9
Ensembl ID : ENSG00000240065
Description: proteasome 20S subunit beta 9
Gene Synonyms: BETA1I,LMP2,PSMB6I,RING12
6 APIs:
214 Possible Orthologues:

HIV Infection R-HSA-162906
HIV Infection R-HSA-162906
Disease R-HSA-1643685
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PIP3 activates AKT signaling R-HSA-1257604
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of amino acids and derivatives R-HSA-71291
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G2/M Checkpoints R-HSA-69481
Hh mutants are degraded by ERAD R-HSA-5362768
Apoptosis R-HSA-109581
DNA Replication R-HSA-69306
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
ER-Phagosome pathway R-HSA-1236974
Switching of origins to a post-replicative state R-HSA-69052
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular responses to stimuli R-HSA-8953897
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC-family proteins mediated transport R-HSA-382556
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Immune System R-HSA-168256
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of RNA R-HSA-8953854
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
RNA Polymerase II Transcription R-HSA-73857
Signaling by Hedgehog R-HSA-5358351
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of GLI1 by the proteasome R-HSA-5610780
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by WNT R-HSA-195721
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Metaphase and Anaphase R-HSA-2555396
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 family signaling R-HSA-446652
Ub-specific processing proteases R-HSA-5689880
Cell Cycle R-HSA-1640170
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by NOTCH4 R-HSA-9013694
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of DVL R-HSA-4641258
Downstream TCR signaling R-HSA-202424
MAPK family signaling cascades R-HSA-5683057
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
Defective CFTR causes cystic fibrosis R-HSA-5678895
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disease R-HSA-1643685
G2/M Transition R-HSA-69275
Neddylation R-HSA-8951664
Hedgehog ligand biogenesis R-HSA-5358346
Generic Transcription Pathway R-HSA-212436
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog 'on' state R-HSA-5632684
G1/S Transition R-HSA-69206
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Regulation of RUNX3 expression and activity R-HSA-8941858
Host Interactions of HIV factors R-HSA-162909
Nervous system development R-HSA-9675108
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by NOTCH R-HSA-157118
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
S Phase R-HSA-69242
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of AXIN R-HSA-4641257
UCH proteinases R-HSA-5689603
Assembly of the pre-replicative complex R-HSA-68867
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Interleukin-1 signaling R-HSA-9020702
TCR signaling R-HSA-202403
p53-Dependent G1 DNA Damage Response R-HSA-69563
PTEN Regulation R-HSA-6807070
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic Anaphase R-HSA-68882
Separation of Sister Chromatids R-HSA-2467813
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to hypoxia R-HSA-1234174
Transport of small molecules R-HSA-382551
Gene expression (Transcription) R-HSA-74160
TCF dependent signaling in response to WNT R-HSA-201681
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
Metabolism of polyamines R-HSA-351202
Programmed Cell Death R-HSA-5357801
Intracellular signaling by second messengers R-HSA-9006925
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
M Phase R-HSA-68886
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of GLI2 by the proteasome R-HSA-5610783
Class I MHC mediated antigen processing & presentation R-HSA-983169
Developmental Biology R-HSA-1266738
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RAF/MAP kinase cascade R-HSA-5673001
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of RAS by GAPs R-HSA-5658442
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Hedgehog 'off' state R-HSA-5610787
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular response to chemical stress R-HSA-9711123
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
HIV Infection R-HSA-162906
KEAP1-NFE2L2 pathway R-HSA-9755511
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of Apoptosis R-HSA-169911
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK1/MAPK3 signaling R-HSA-5684996
ABC transporter disorders R-HSA-5619084
Cell Cycle, Mitotic R-HSA-69278
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stress R-HSA-2262752
Antigen processing-Cross presentation R-HSA-1236975
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX3 R-HSA-8878159
Post-translational protein modification R-HSA-597592
Metabolism R-HSA-1430728
Mitotic G2-G2/M phases R-HSA-453274
Stabilization of p53 R-HSA-69541
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
Hh mutants abrogate ligand secretion R-HSA-5387390
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism R-HSA-1430728
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Vif-mediated degradation of APOBEC3G R-HSA-180585
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of RNA R-HSA-8953854
DNA Replication R-HSA-69306
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S Transition R-HSA-69206
Programmed Cell Death R-HSA-5357801
Adaptive Immune System R-HSA-1280218
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Hedgehog 'off' state R-HSA-5610787
Asymmetric localization of PCP proteins R-HSA-4608870
ER-Phagosome pathway R-HSA-1236974
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle Checkpoints R-HSA-69620
Disorders of transmembrane transporters R-HSA-5619115
Interleukin-1 family signaling R-HSA-446652
Stabilization of p53 R-HSA-69541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
G2/M Checkpoints R-HSA-69481
Cell Cycle, Mitotic R-HSA-69278
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PIP3 activates AKT signaling R-HSA-1257604
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK6/MAPK4 signaling R-HSA-5687128
RAF/MAP kinase cascade R-HSA-5673001
Vpu mediated degradation of CD4 R-HSA-180534
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Cellular response to chemical stress R-HSA-9711123
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by ROBO receptors R-HSA-376176
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signal Transduction R-HSA-162582
Mitotic Metaphase and Anaphase R-HSA-2555396
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing-Cross presentation R-HSA-1236975
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
Switching of origins to a post-replicative state R-HSA-69052
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RUNX3 expression and activity R-HSA-8941858
PCP/CE pathway R-HSA-4086400
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G2/M Transition R-HSA-69275
Nuclear events mediated by NFE2L2 R-HSA-9759194
C-type lectin receptors (CLRs) R-HSA-5621481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Orc1 removal from chromatin R-HSA-68949
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
Signaling by Interleukins R-HSA-449147
Signaling by WNT R-HSA-195721
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog ligand biogenesis R-HSA-5358346
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Separation of Sister Chromatids R-HSA-2467813
Hedgehog 'on' state R-HSA-5632684
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle R-HSA-1640170
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI2 by the proteasome R-HSA-5610783
ABC transporter disorders R-HSA-5619084
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stress R-HSA-2262752
UCH proteinases R-HSA-5689603
Hh mutants are degraded by ERAD R-HSA-5362768
Disease R-HSA-1643685
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic Anaphase R-HSA-68882
Apoptosis R-HSA-109581
S Phase R-HSA-69242
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Metabolism of proteins R-HSA-392499
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of polyamines R-HSA-351202
Downstream TCR signaling R-HSA-202424
Hh mutants abrogate ligand secretion R-HSA-5387390
Deubiquitination R-HSA-5688426
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Immune System R-HSA-168256
TCF dependent signaling in response to WNT R-HSA-201681
Developmental Biology R-HSA-1266738
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mitotic cell cycle R-HSA-453276
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
Synthesis of DNA R-HSA-69239
Regulation of PTEN stability and activity R-HSA-8948751
KEAP1-NFE2L2 pathway R-HSA-9755511
Host Interactions of HIV factors R-HSA-162909
Nervous system development R-HSA-9675108
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Generic Transcription Pathway R-HSA-212436
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Axon guidance R-HSA-422475
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular response to hypoxia R-HSA-1234174
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
TCR signaling R-HSA-202403
Signaling by NOTCH R-HSA-157118
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Interleukin-1 signaling R-HSA-9020702
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by NOTCH4 R-HSA-9013694
RNA Polymerase II Transcription R-HSA-73857
Degradation of DVL R-HSA-4641258
Innate Immune System R-HSA-168249
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX3 R-HSA-8878159
Post-translational protein modification R-HSA-597592
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transport of small molecules R-HSA-382551
FCERI mediated NF-kB activation R-HSA-2871837
G1/S DNA Damage Checkpoints R-HSA-69615
PTEN Regulation R-HSA-6807070
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
M Phase R-HSA-68886
MAPK1/MAPK3 signaling R-HSA-5684996
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Activation of NF-kappaB in B cells R-HSA-1169091
Synthesis of DNA R-HSA-69239
Mitotic G1 phase and G1/S transition R-HSA-453279
Hh mutants are degraded by ERAD R-HSA-5362768
Class I MHC mediated antigen processing & presentation R-HSA-983169
M Phase R-HSA-68886
Regulation of PTEN stability and activity R-HSA-8948751
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Neddylation R-HSA-8951664
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
ABC transporter disorders R-HSA-5619084
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Axon guidance R-HSA-422475
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
Antigen processing-Cross presentation R-HSA-1236975
p53-Dependent G1 DNA Damage Response R-HSA-69563
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Separation of Sister Chromatids R-HSA-2467813
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
p53-Independent DNA Damage Response R-HSA-69610
DNA Replication R-HSA-69306
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of RNA R-HSA-8953854
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX3 R-HSA-8878159
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of RUNX3 expression and activity R-HSA-8941858
Disease R-HSA-1643685
G2/M Transition R-HSA-69275
Transcriptional regulation by RUNX1 R-HSA-8878171
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Innate Immune System R-HSA-168249
Hedgehog 'on' state R-HSA-5632684
Metabolism R-HSA-1430728
Regulation of RUNX2 expression and activity R-HSA-8939902
Cytokine Signaling in Immune system R-HSA-1280215
DNA Replication Pre-Initiation R-HSA-69002
Degradation of AXIN R-HSA-4641257
Generic Transcription Pathway R-HSA-212436
Transport of small molecules R-HSA-382551
PIP3 activates AKT signaling R-HSA-1257604
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle R-HSA-1640170
Cellular responses to stimuli R-HSA-8953897
Cell Cycle Checkpoints R-HSA-69620
Metabolism of proteins R-HSA-392499
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ER-Phagosome pathway R-HSA-1236974
Signaling by NOTCH4 R-HSA-9013694
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Apoptosis R-HSA-109581
Interleukin-1 signaling R-HSA-9020702
Degradation of GLI2 by the proteasome R-HSA-5610783
RNA Polymerase II Transcription R-HSA-73857
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RAS by GAPs R-HSA-5658442
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Negative regulation of NOTCH4 signaling R-HSA-9604323
Vif-mediated degradation of APOBEC3G R-HSA-180585
Infectious disease R-HSA-5663205
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PCP/CE pathway R-HSA-4086400
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of Apoptosis R-HSA-169911
Assembly of the pre-replicative complex R-HSA-68867
Signaling by Hedgehog R-HSA-5358351
Signaling by ROBO receptors R-HSA-376176
PTEN Regulation R-HSA-6807070
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to chemical stress R-HSA-9711123
Signaling by Interleukins R-HSA-449147
Hh mutants abrogate ligand secretion R-HSA-5387390
FCERI mediated NF-kB activation R-HSA-2871837
Beta-catenin independent WNT signaling R-HSA-3858494
RAF/MAP kinase cascade R-HSA-5673001
Disorders of transmembrane transporters R-HSA-5619115
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Deubiquitination R-HSA-5688426
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
S Phase R-HSA-69242
Signal Transduction R-HSA-162582
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of GLI1 by the proteasome R-HSA-5610780
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle, Mitotic R-HSA-69278
Degradation of DVL R-HSA-4641258
Adaptive Immune System R-HSA-1280218
Signaling by WNT R-HSA-195721
ABC-family proteins mediated transport R-HSA-382556
MAPK6/MAPK4 signaling R-HSA-5687128
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular responses to stress R-HSA-2262752
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
Gene expression (Transcription) R-HSA-74160
G1/S Transition R-HSA-69206
Immune System R-HSA-168256
Ub-specific processing proteases R-HSA-5689880
TCF dependent signaling in response to WNT R-HSA-201681
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-1 family signaling R-HSA-446652
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Orc1 removal from chromatin R-HSA-68949
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of amino acids and derivatives R-HSA-71291
Nervous system development R-HSA-9675108
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic Anaphase R-HSA-68882
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Post-translational protein modification R-HSA-597592
Hedgehog 'off' state R-HSA-5610787
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Stabilization of p53 R-HSA-69541
UCH proteinases R-HSA-5689603
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism of polyamines R-HSA-351202
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by NOTCH R-HSA-157118
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G2-G2/M phases R-HSA-453274
G2/M Checkpoints R-HSA-69481
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Programmed Cell Death R-HSA-5357801
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
FCERI mediated NF-kB activation R-HSA-2871837
G1/S DNA Damage Checkpoints R-HSA-69615
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
C-type lectin receptors (CLRs) R-HSA-5621481
Synthesis of DNA R-HSA-69239
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stress R-HSA-2262752
Transport of small molecules R-HSA-382551
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 family signaling R-HSA-446652
Mitotic G1 phase and G1/S transition R-HSA-453279
Axon guidance R-HSA-422475
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'on' state R-HSA-5632684
Vpu mediated degradation of CD4 R-HSA-180534
Disease R-HSA-1643685
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PTEN Regulation R-HSA-6807070
Beta-catenin independent WNT signaling R-HSA-3858494
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of AXIN R-HSA-4641257
Host Interactions of HIV factors R-HSA-162909
G2/M Transition R-HSA-69275
Developmental Biology R-HSA-1266738
TCF dependent signaling in response to WNT R-HSA-201681
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
Post-translational protein modification R-HSA-597592
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism R-HSA-1430728
MAPK family signaling cascades R-HSA-5683057
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
Signaling by ROBO receptors R-HSA-376176
Regulation of RAS by GAPs R-HSA-5658442
Asymmetric localization of PCP proteins R-HSA-4608870
Assembly of the pre-replicative complex R-HSA-68867
Signaling by NOTCH R-HSA-157118
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular response to chemical stress R-HSA-9711123
Mitotic G2-G2/M phases R-HSA-453274
Cellular responses to stimuli R-HSA-8953897
Nervous system development R-HSA-9675108
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
KEAP1-NFE2L2 pathway R-HSA-9755511
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Interleukin-1 signaling R-HSA-9020702
Metabolism of polyamines R-HSA-351202
Downstream TCR signaling R-HSA-202424
Degradation of DVL R-HSA-4641258
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Innate Immune System R-HSA-168249
Antigen processing-Cross presentation R-HSA-1236975
Hh mutants abrogate ligand secretion R-HSA-5387390
Disorders of transmembrane transporters R-HSA-5619115
Apoptosis R-HSA-109581
PCP/CE pathway R-HSA-4086400
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by NOTCH4 R-HSA-9013694
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1 DNA Damage Response R-HSA-69563
Intracellular signaling by second messengers R-HSA-9006925
DNA Replication Pre-Initiation R-HSA-69002
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Activation of NF-kappaB in B cells R-HSA-1169091
UCH proteinases R-HSA-5689603
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Hh mutants are degraded by ERAD R-HSA-5362768
G1/S Transition R-HSA-69206
ER-Phagosome pathway R-HSA-1236974
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RUNX2 expression and activity R-HSA-8939902
Programmed Cell Death R-HSA-5357801
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G2/M Checkpoints R-HSA-69481
Deubiquitination R-HSA-5688426
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by Hedgehog R-HSA-5358351
Immune System R-HSA-168256
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
M Phase R-HSA-68886
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
DNA Replication R-HSA-69306
Signaling by WNT R-HSA-195721
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle, Mitotic R-HSA-69278
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neddylation R-HSA-8951664
MAPK6/MAPK4 signaling R-HSA-5687128
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Anaphase R-HSA-68882
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle Checkpoints R-HSA-69620
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of Apoptosis R-HSA-169911
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism of RNA R-HSA-8953854
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of GLI2 by the proteasome R-HSA-5610783
Ub-specific processing proteases R-HSA-5689880
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of mitotic cell cycle R-HSA-453276
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
MAPK family signaling cascades R-HSA-5683057
Hedgehog 'on' state R-HSA-5632684
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
ABC transporter disorders R-HSA-5619084
Regulation of Apoptosis R-HSA-169911
Transport of small molecules R-HSA-382551
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
Ub-specific processing proteases R-HSA-5689880
PIP3 activates AKT signaling R-HSA-1257604
PCP/CE pathway R-HSA-4086400
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hedgehog ligand biogenesis R-HSA-5358346
Beta-catenin independent WNT signaling R-HSA-3858494
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vif-mediated degradation of APOBEC3G R-HSA-180585
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants are degraded by ERAD R-HSA-5362768
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nervous system development R-HSA-9675108
Deubiquitination R-HSA-5688426
Antigen processing-Cross presentation R-HSA-1236975
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Host Interactions of HIV factors R-HSA-162909
Negative regulation of NOTCH4 signaling R-HSA-9604323
Stabilization of p53 R-HSA-69541
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by NOTCH R-HSA-157118
RNA Polymerase II Transcription R-HSA-73857
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Programmed Cell Death R-HSA-5357801
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mitotic cell cycle R-HSA-453276
Regulation of RUNX2 expression and activity R-HSA-8939902
Interleukin-1 family signaling R-HSA-446652
S Phase R-HSA-69242
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
DNA Replication Pre-Initiation R-HSA-69002
UCH proteinases R-HSA-5689603
Signaling by Hedgehog R-HSA-5358351
Signaling by ROBO receptors R-HSA-376176
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic Anaphase R-HSA-68882
HIV Infection R-HSA-162906
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
TCR signaling R-HSA-202403
Adaptive Immune System R-HSA-1280218
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of expression of SLITs and ROBOs R-HSA-9010553
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Synthesis of DNA R-HSA-69239
Neddylation R-HSA-8951664
DNA Replication R-HSA-69306
Asymmetric localization of PCP proteins R-HSA-4608870
CLEC7A (Dectin-1) signaling R-HSA-5607764
Axon guidance R-HSA-422475
G2/M Transition R-HSA-69275
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
Hh mutants abrogate ligand secretion R-HSA-5387390
ABC-family proteins mediated transport R-HSA-382556
Gene expression (Transcription) R-HSA-74160
Degradation of DVL R-HSA-4641258
Intracellular signaling by second messengers R-HSA-9006925
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent DNA Damage Response R-HSA-69610
Degradation of AXIN R-HSA-4641257
Switching of origins to a post-replicative state R-HSA-69052
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH4 R-HSA-9013694
ER-Phagosome pathway R-HSA-1236974
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Interleukin-1 signaling R-HSA-9020702
Mitotic Metaphase and Anaphase R-HSA-2555396
Cyclin E associated events during G1/S transition R-HSA-69202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK1/MAPK3 signaling R-HSA-5684996
C-type lectin receptors (CLRs) R-HSA-5621481
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle, Mitotic R-HSA-69278
Metabolism of polyamines R-HSA-351202
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
M Phase R-HSA-68886
Separation of Sister Chromatids R-HSA-2467813
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by WNT R-HSA-195721
G1/S DNA Damage Checkpoints R-HSA-69615
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of RNA R-HSA-8953854
Regulation of PTEN stability and activity R-HSA-8948751
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle Checkpoints R-HSA-69620
G1/S Transition R-HSA-69206
Developmental Biology R-HSA-1266738
Hedgehog 'off' state R-HSA-5610787
KEAP1-NFE2L2 pathway R-HSA-9755511
Disorders of transmembrane transporters R-HSA-5619115
Cellular response to hypoxia R-HSA-1234174
Defective CFTR causes cystic fibrosis R-HSA-5678895
PTEN Regulation R-HSA-6807070
MAPK6/MAPK4 signaling R-HSA-5687128
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cytokine Signaling in Immune system R-HSA-1280215
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Downstream TCR signaling R-HSA-202424
Regulation of RAS by GAPs R-HSA-5658442
G2/M Checkpoints R-HSA-69481
Degradation of GLI2 by the proteasome R-HSA-5610783
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Post-translational protein modification R-HSA-597592
Nuclear events mediated by NFE2L2 R-HSA-9759194
Orc1 removal from chromatin R-HSA-68949
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Nervous system development R-HSA-9675108
Signaling by Hedgehog R-HSA-5358351
DNA Replication Pre-Initiation R-HSA-69002
Separation of Sister Chromatids R-HSA-2467813
Gene expression (Transcription) R-HSA-74160
Degradation of beta-catenin by the destruction complex R-HSA-195253
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by Interleukins R-HSA-449147
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of Apoptosis R-HSA-169911
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX1 R-HSA-8878171
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
Transport of small molecules R-HSA-382551
DNA Replication R-HSA-69306
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream TCR signaling R-HSA-202424
Mitotic G1 phase and G1/S transition R-HSA-453279
KEAP1-NFE2L2 pathway R-HSA-9755511
G1/S DNA Damage Checkpoints R-HSA-69615
TCR signaling R-HSA-202403
MAPK1/MAPK3 signaling R-HSA-5684996
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Vpu mediated degradation of CD4 R-HSA-180534
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'on' state R-HSA-5632684
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular response to chemical stress R-HSA-9711123
PCP/CE pathway R-HSA-4086400
Signaling by NOTCH R-HSA-157118
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of RUNX2 expression and activity R-HSA-8939902
Orc1 removal from chromatin R-HSA-68949
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of RNA R-HSA-8953854
Transcriptional regulation by RUNX3 R-HSA-8878159
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G2/M Checkpoints R-HSA-69481
Degradation of AXIN R-HSA-4641257
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular response to hypoxia R-HSA-1234174
Assembly of the pre-replicative complex R-HSA-68867
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ub-specific processing proteases R-HSA-5689880
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Interleukin-1 signaling R-HSA-9020702
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Disease R-HSA-1643685
M Phase R-HSA-68886
C-type lectin receptors (CLRs) R-HSA-5621481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-1 family signaling R-HSA-446652
Apoptosis R-HSA-109581
G1/S Transition R-HSA-69206
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cyclin E associated events during G1/S transition R-HSA-69202
Deubiquitination R-HSA-5688426
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Switching of origins to a post-replicative state R-HSA-69052
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI1 by the proteasome R-HSA-5610780
Innate Immune System R-HSA-168249
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Adaptive Immune System R-HSA-1280218
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Post-translational protein modification R-HSA-597592
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle Checkpoints R-HSA-69620
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by ROBO receptors R-HSA-376176
Stabilization of p53 R-HSA-69541
Mitotic Anaphase R-HSA-68882
Mitotic G2-G2/M phases R-HSA-453274
PTEN Regulation R-HSA-6807070
UCH proteinases R-HSA-5689603
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'off' state R-HSA-5610787
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle, Mitotic R-HSA-69278
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
Metabolism R-HSA-1430728
Regulation of RAS by GAPs R-HSA-5658442
Signaling by NOTCH4 R-HSA-9013694
Regulation of mitotic cell cycle R-HSA-453276
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
ABC-family proteins mediated transport R-HSA-382556
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants are degraded by ERAD R-HSA-5362768
RNA Polymerase II Transcription R-HSA-73857
G2/M Transition R-HSA-69275
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog ligand biogenesis R-HSA-5358346
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of NF-kappaB in B cells R-HSA-1169091
ABC transporter disorders R-HSA-5619084
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Nuclear events mediated by NFE2L2 R-HSA-9759194
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cytokine Signaling in Immune system R-HSA-1280215
Axon guidance R-HSA-422475
Programmed Cell Death R-HSA-5357801
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of proteins R-HSA-392499
Synthesis of DNA R-HSA-69239
Signaling by WNT R-HSA-195721
Intracellular signaling by second messengers R-HSA-9006925
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Generic Transcription Pathway R-HSA-212436
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Host Interactions of HIV factors R-HSA-162909
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Metaphase and Anaphase R-HSA-2555396
Disorders of transmembrane transporters R-HSA-5619115
Disease R-HSA-1643685
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of proteins R-HSA-392499
Class I MHC mediated antigen processing & presentation R-HSA-983169
Innate Immune System R-HSA-168249
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Switching of origins to a post-replicative state R-HSA-69052
Separation of Sister Chromatids R-HSA-2467813
Cellular response to hypoxia R-HSA-1234174
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
Vpu mediated degradation of CD4 R-HSA-180534
C-type lectin receptors (CLRs) R-HSA-5621481
M Phase R-HSA-68886
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog ligand biogenesis R-HSA-5358346
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PCP/CE pathway R-HSA-4086400
Regulation of RUNX2 expression and activity R-HSA-8939902
Developmental Biology R-HSA-1266738
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX1 R-HSA-8878171
PTEN Regulation R-HSA-6807070
ABC transporter disorders R-HSA-5619084
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX3 R-HSA-8878159
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of PTEN stability and activity R-HSA-8948751
ABC-family proteins mediated transport R-HSA-382556
Regulation of mitotic cell cycle R-HSA-453276
MAPK family signaling cascades R-HSA-5683057
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog 'on' state R-HSA-5632684
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
MAPK1/MAPK3 signaling R-HSA-5684996
S Phase R-HSA-69242
Degradation of AXIN R-HSA-4641257
Beta-catenin independent WNT signaling R-HSA-3858494
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by Hedgehog R-HSA-5358351
Cell Cycle Checkpoints R-HSA-69620
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of RAS by GAPs R-HSA-5658442
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cytokine Signaling in Immune system R-HSA-1280215
Nervous system development R-HSA-9675108
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of RNA R-HSA-8953854
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Nuclear events mediated by NFE2L2 R-HSA-9759194
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH R-HSA-157118
RAF/MAP kinase cascade R-HSA-5673001
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Activation of NF-kappaB in B cells R-HSA-1169091
UCH proteinases R-HSA-5689603
Ub-specific processing proteases R-HSA-5689880
Deubiquitination R-HSA-5688426
TCF dependent signaling in response to WNT R-HSA-201681
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
G1/S DNA Damage Checkpoints R-HSA-69615
KEAP1-NFE2L2 pathway R-HSA-9755511
Transport of small molecules R-HSA-382551
Cellular responses to stimuli R-HSA-8953897
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Programmed Cell Death R-HSA-5357801
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog 'off' state R-HSA-5610787
Interleukin-1 family signaling R-HSA-446652
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Interleukins R-HSA-449147
Metabolism of polyamines R-HSA-351202
Assembly of the pre-replicative complex R-HSA-68867
Stabilization of p53 R-HSA-69541
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
Orc1 removal from chromatin R-HSA-68949
Cell Cycle, Mitotic R-HSA-69278
Degradation of DVL R-HSA-4641258
NIK-->noncanonical NF-kB signaling R-HSA-5676590
DNA Replication R-HSA-69306
Cellular response to chemical stress R-HSA-9711123
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hh mutants are degraded by ERAD R-HSA-5362768
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Axon guidance R-HSA-422475
G2/M Transition R-HSA-69275
DNA Replication Pre-Initiation R-HSA-69002
Asymmetric localization of PCP proteins R-HSA-4608870
Signal Transduction R-HSA-162582
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G1 phase and G1/S transition R-HSA-453279
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Immune System R-HSA-168256
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Anaphase R-HSA-68882
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Post-translational protein modification R-HSA-597592
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
ER-Phagosome pathway R-HSA-1236974
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
p53-Independent DNA Damage Response R-HSA-69610
Intracellular signaling by second messengers R-HSA-9006925
Signaling by NOTCH4 R-HSA-9013694
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of Apoptosis R-HSA-169911
Synthesis of DNA R-HSA-69239
MAPK6/MAPK4 signaling R-HSA-5687128
Neddylation R-HSA-8951664
Interleukin-1 signaling R-HSA-9020702
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
HIV Infection R-HSA-162906
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by WNT R-HSA-195721
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of AXIN R-HSA-4641257
Degradation of GLI1 by the proteasome R-HSA-5610780
Switching of origins to a post-replicative state R-HSA-69052
Gene expression (Transcription) R-HSA-74160
Cellular response to chemical stress R-HSA-9711123
Assembly of the pre-replicative complex R-HSA-68867
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Nervous system development R-HSA-9675108
UCH proteinases R-HSA-5689603
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Generic Transcription Pathway R-HSA-212436
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hedgehog ligand biogenesis R-HSA-5358346
Cytokine Signaling in Immune system R-HSA-1280215
Infectious disease R-HSA-5663205
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX1 R-HSA-8878171
G2/M Checkpoints R-HSA-69481
DNA Replication R-HSA-69306
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of RNA R-HSA-8953854
Defective CFTR causes cystic fibrosis R-HSA-5678895
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism of polyamines R-HSA-351202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RNA Polymerase II Transcription R-HSA-73857
DNA Replication Pre-Initiation R-HSA-69002
Orc1 removal from chromatin R-HSA-68949
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing-Cross presentation R-HSA-1236975
TCF dependent signaling in response to WNT R-HSA-201681
Developmental Biology R-HSA-1266738
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
Mitotic G2-G2/M phases R-HSA-453274
Signal Transduction R-HSA-162582
PCP/CE pathway R-HSA-4086400
Stabilization of p53 R-HSA-69541
Nuclear events mediated by NFE2L2 R-HSA-9759194
S Phase R-HSA-69242
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hedgehog 'on' state R-HSA-5632684
Signaling by NOTCH4 R-HSA-9013694
Host Interactions of HIV factors R-HSA-162909
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PTEN Regulation R-HSA-6807070
M Phase R-HSA-68886
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle Checkpoints R-HSA-69620
Cellular response to hypoxia R-HSA-1234174
Transport of small molecules R-HSA-382551
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
Degradation of beta-catenin by the destruction complex R-HSA-195253
Axon guidance R-HSA-422475
Separation of Sister Chromatids R-HSA-2467813
ABC-family proteins mediated transport R-HSA-382556
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by the B Cell Receptor (BCR) R-HSA-983705
MAPK1/MAPK3 signaling R-HSA-5684996
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by ROBO receptors R-HSA-376176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of GLI2 by the proteasome R-HSA-5610783
Adaptive Immune System R-HSA-1280218
HIV Infection R-HSA-162906
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle R-HSA-1640170
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic Anaphase R-HSA-68882
NIK-->noncanonical NF-kB signaling R-HSA-5676590
G1/S DNA Damage Checkpoints R-HSA-69615
Downstream TCR signaling R-HSA-202424
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
Disease R-HSA-1643685
G2/M Transition R-HSA-69275
Cellular responses to stimuli R-HSA-8953897
Degradation of DVL R-HSA-4641258
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Synthesis of DNA R-HSA-69239
Interleukin-1 family signaling R-HSA-446652
Disorders of transmembrane transporters R-HSA-5619115
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle, Mitotic R-HSA-69278
Vpu mediated degradation of CD4 R-HSA-180534
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of Apoptosis R-HSA-169911
Negative regulation of NOTCH4 signaling R-HSA-9604323
TCR signaling R-HSA-202403
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
ER-Phagosome pathway R-HSA-1236974
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog 'off' state R-HSA-5610787
Regulation of RAS by GAPs R-HSA-5658442
G1/S Transition R-HSA-69206
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of proteins R-HSA-392499
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stress R-HSA-2262752
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX2 R-HSA-8878166
ABC transporter disorders R-HSA-5619084
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Neddylation R-HSA-8951664
Intracellular signaling by second messengers R-HSA-9006925
CLEC7A (Dectin-1) signaling R-HSA-5607764
Ub-specific processing proteases R-HSA-5689880
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Apoptosis R-HSA-109581
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by NOTCH R-HSA-157118
RAF/MAP kinase cascade R-HSA-5673001
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK family signaling cascades R-HSA-5683057
C-type lectin receptors (CLRs) R-HSA-5621481
Assembly of the pre-replicative complex R-HSA-68867
Cellular response to hypoxia R-HSA-1234174
Regulation of expression of SLITs and ROBOs R-HSA-9010553
p53-Independent DNA Damage Response R-HSA-69610
MAPK1/MAPK3 signaling R-HSA-5684996
ABC transporter disorders R-HSA-5619084
PCP/CE pathway R-HSA-4086400
Signaling by WNT R-HSA-195721
Antigen processing-Cross presentation R-HSA-1236975
Beta-catenin independent WNT signaling R-HSA-3858494
Cytokine Signaling in Immune system R-HSA-1280215
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
S Phase R-HSA-69242
Disease R-HSA-1643685
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
HIV Infection R-HSA-162906
Signal Transduction R-HSA-162582
DNA Replication Pre-Initiation R-HSA-69002
DNA Replication R-HSA-69306
Signaling by Interleukins R-HSA-449147
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ABC-family proteins mediated transport R-HSA-382556
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream TCR signaling R-HSA-202424
UCH proteinases R-HSA-5689603
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Deubiquitination R-HSA-5688426
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
C-type lectin receptors (CLRs) R-HSA-5621481
Gene expression (Transcription) R-HSA-74160
Asymmetric localization of PCP proteins R-HSA-4608870
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of beta-catenin by the destruction complex R-HSA-195253
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
Host Interactions of HIV factors R-HSA-162909
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
M Phase R-HSA-68886
Ub-specific processing proteases R-HSA-5689880
Regulation of Apoptosis R-HSA-169911
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Class I MHC mediated antigen processing & presentation R-HSA-983169
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Nuclear events mediated by NFE2L2 R-HSA-9759194
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of amino acids and derivatives R-HSA-71291
PIP3 activates AKT signaling R-HSA-1257604
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
G2/M Checkpoints R-HSA-69481
Degradation of DVL R-HSA-4641258
Hedgehog 'off' state R-HSA-5610787
Separation of Sister Chromatids R-HSA-2467813
Axon guidance R-HSA-422475
Degradation of AXIN R-HSA-4641257
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX3 R-HSA-8878159
Interleukin-1 signaling R-HSA-9020702
Transport of small molecules R-HSA-382551
Negative regulation of NOTCH4 signaling R-HSA-9604323
Mitotic Anaphase R-HSA-68882
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic G1 phase and G1/S transition R-HSA-453279
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog 'on' state R-HSA-5632684
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Switching of origins to a post-replicative state R-HSA-69052
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S Transition R-HSA-69206
Hedgehog ligand biogenesis R-HSA-5358346
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH R-HSA-157118
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Stabilization of p53 R-HSA-69541
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism R-HSA-1430728
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Infectious disease R-HSA-5663205
Regulation of mitotic cell cycle R-HSA-453276
Nervous system development R-HSA-9675108
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Transition R-HSA-69275
Regulation of RAS by GAPs R-HSA-5658442
Signaling by ROBO receptors R-HSA-376176
Signaling by NOTCH4 R-HSA-9013694
Disorders of transmembrane transporters R-HSA-5619115
Orc1 removal from chromatin R-HSA-68949
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCR signaling R-HSA-202403
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
RAF/MAP kinase cascade R-HSA-5673001
Cellular response to chemical stress R-HSA-9711123
Mitotic G2-G2/M phases R-HSA-453274
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle R-HSA-1640170
Cyclin E associated events during G1/S transition R-HSA-69202
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Post-translational protein modification R-HSA-597592
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX1 R-HSA-8878171
Vif-mediated degradation of APOBEC3G R-HSA-180585
Developmental Biology R-HSA-1266738
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle, Mitotic R-HSA-69278
Interleukin-1 family signaling R-HSA-446652
Programmed Cell Death R-HSA-5357801
Generic Transcription Pathway R-HSA-212436
Signaling by the B Cell Receptor (BCR) R-HSA-983705
MAPK family signaling cascades R-HSA-5683057
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
TCF dependent signaling in response to WNT R-HSA-201681
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of proteins R-HSA-392499
Metabolism of polyamines R-HSA-351202
Apoptosis R-HSA-109581
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of PTEN stability and activity R-HSA-8948751
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of RNA R-HSA-8953854
Neddylation R-HSA-8951664
Immune System R-HSA-168256
ER-Phagosome pathway R-HSA-1236974
Adaptive Immune System R-HSA-1280218
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic Anaphase R-HSA-68882
Disease R-HSA-1643685
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular response to chemical stress R-HSA-9711123
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
M Phase R-HSA-68886
Signaling by ROBO receptors R-HSA-376176
Assembly of the pre-replicative complex R-HSA-68867
Hh mutants abrogate ligand secretion R-HSA-5387390
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 signaling R-HSA-9020702
Regulation of RUNX2 expression and activity R-HSA-8939902
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream TCR signaling R-HSA-202424
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog ligand biogenesis R-HSA-5358346
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of GLI2 by the proteasome R-HSA-5610783
G2/M Checkpoints R-HSA-69481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of GLI1 by the proteasome R-HSA-5610780
Antigen processing-Cross presentation R-HSA-1236975
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle, Mitotic R-HSA-69278
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular response to hypoxia R-HSA-1234174
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Host Interactions of HIV factors R-HSA-162909
Disorders of transmembrane transporters R-HSA-5619115
Transcriptional regulation by RUNX3 R-HSA-8878159
Vpu mediated degradation of CD4 R-HSA-180534
Innate Immune System R-HSA-168249
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Infectious disease R-HSA-5663205
Regulation of Apoptosis R-HSA-169911
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Axon guidance R-HSA-422475
Immune System R-HSA-168256
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ABC-family proteins mediated transport R-HSA-382556
Regulation of RAS by GAPs R-HSA-5658442
Neddylation R-HSA-8951664
Adaptive Immune System R-HSA-1280218
Defective CFTR causes cystic fibrosis R-HSA-5678895
G1/S Transition R-HSA-69206
Negative regulation of NOTCH4 signaling R-HSA-9604323
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nervous system development R-HSA-9675108
ABC transporter disorders R-HSA-5619084
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ER-Phagosome pathway R-HSA-1236974
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PTEN Regulation R-HSA-6807070
Signaling by the B Cell Receptor (BCR) R-HSA-983705
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent DNA Damage Response R-HSA-69610
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism R-HSA-1430728
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ub-specific processing proteases R-HSA-5689880
Metabolism of polyamines R-HSA-351202
Regulation of PTEN stability and activity R-HSA-8948751
NIK-->noncanonical NF-kB signaling R-HSA-5676590
HIV Infection R-HSA-162906
Stabilization of p53 R-HSA-69541
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle Checkpoints R-HSA-69620
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic Metaphase and Anaphase R-HSA-2555396
PIP3 activates AKT signaling R-HSA-1257604
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Switching of origins to a post-replicative state R-HSA-69052
Orc1 removal from chromatin R-HSA-68949
Metabolism of RNA R-HSA-8953854
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Post-translational protein modification R-HSA-597592
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stress R-HSA-2262752
Regulation of mitotic cell cycle R-HSA-453276
Programmed Cell Death R-HSA-5357801
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of proteins R-HSA-392499
Signaling by Interleukins R-HSA-449147
Signaling by WNT R-HSA-195721
Interleukin-1 family signaling R-HSA-446652
Apoptosis R-HSA-109581
FCERI mediated NF-kB activation R-HSA-2871837
TCR signaling R-HSA-202403
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by NOTCH4 R-HSA-9013694
Transport of small molecules R-HSA-382551
Hh mutants are degraded by ERAD R-HSA-5362768
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hedgehog 'off' state R-HSA-5610787
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX2 R-HSA-8878166
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Asymmetric localization of PCP proteins R-HSA-4608870
PCP/CE pathway R-HSA-4086400
DNA Replication R-HSA-69306
Signal Transduction R-HSA-162582
Hedgehog 'on' state R-HSA-5632684
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Gene expression (Transcription) R-HSA-74160
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of DVL R-HSA-4641258
Beta-catenin independent WNT signaling R-HSA-3858494
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCF dependent signaling in response to WNT R-HSA-201681
Synthesis of DNA R-HSA-69239
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
UCH proteinases R-HSA-5689603
Regulation of RUNX3 expression and activity R-HSA-8941858
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX1 R-HSA-8878171
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle R-HSA-1640170
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Intracellular signaling by second messengers R-HSA-9006925
Cellular responses to stimuli R-HSA-8953897
Signaling by Hedgehog R-HSA-5358351
MAPK family signaling cascades R-HSA-5683057
Degradation of AXIN R-HSA-4641257
Signaling by NOTCH R-HSA-157118
Mitotic G2-G2/M phases R-HSA-453274

Expression Atlas ENSG00000240065
NCBI gene (formerly Entrezgene) 5698
GeneCards 9546
HGNC Symbol HGNC:9546
MIM gene 177045
MIM morbid 617591
UniProtKB Gene Name P28065
WikiGene 5698
Gene: PSMD11
Ensembl ID : ENSG00000108671
Description: proteasome 26S subunit, non-ATPase 11
Gene Synonyms: MGC3844,P44.5,RPN6,S9
5 APIs:
283 Possible Orthologues:

DNA Replication R-HSA-69306
Metabolism R-HSA-1430728
Programmed Cell Death R-HSA-5357801
Adaptive Immune System R-HSA-1280218
Activation of NF-kappaB in B cells R-HSA-1169091
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nuclear events mediated by NFE2L2 R-HSA-9759194
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of GLI1 by the proteasome R-HSA-5610780
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
MAPK family signaling cascades R-HSA-5683057
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'on' state R-HSA-5632684
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX1 R-HSA-8878171
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
Intracellular signaling by second messengers R-HSA-9006925
Separation of Sister Chromatids R-HSA-2467813
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle, Mitotic R-HSA-69278
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by WNT R-HSA-195721
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RAF/MAP kinase cascade R-HSA-5673001
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Hedgehog R-HSA-5358351
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
S Phase R-HSA-69242
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Immune System R-HSA-168256
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of RNA R-HSA-8953854
Stabilization of p53 R-HSA-69541
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular response to hypoxia R-HSA-1234174
Mitotic G1 phase and G1/S transition R-HSA-453279
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Downstream TCR signaling R-HSA-202424
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vpu mediated degradation of CD4 R-HSA-180534
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog 'off' state R-HSA-5610787
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism R-HSA-1430728
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
HIV Infection R-HSA-162906
ER-Phagosome pathway R-HSA-1236974
Apoptosis R-HSA-109581
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by NOTCH4 R-HSA-9013694
Neutrophil degranulation R-HSA-6798695
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
p53-Dependent G1 DNA Damage Response R-HSA-69563
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disease R-HSA-1643685
G1/S DNA Damage Checkpoints R-HSA-69615
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
Metabolism of polyamines R-HSA-351202
Deubiquitination R-HSA-5688426
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Metaphase and Anaphase R-HSA-2555396
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cyclin E associated events during G1/S transition R-HSA-69202
G2/M Transition R-HSA-69275
Degradation of AXIN R-HSA-4641257
Assembly of the pre-replicative complex R-HSA-68867
Hh mutants are degraded by ERAD R-HSA-5362768
Vif-mediated degradation of APOBEC3G R-HSA-180585
Generic Transcription Pathway R-HSA-212436
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stress R-HSA-2262752
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
Signal Transduction R-HSA-162582
Mitotic Anaphase R-HSA-68882
Ub-specific processing proteases R-HSA-5689880
TCR signaling R-HSA-202403
Cell Cycle Checkpoints R-HSA-69620
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RUNX3 expression and activity R-HSA-8941858
DNA Replication Pre-Initiation R-HSA-69002
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI2 by the proteasome R-HSA-5610783
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX2 R-HSA-8878166
ABC transporter disorders R-HSA-5619084
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX3 R-HSA-8878159
Defective CFTR causes cystic fibrosis R-HSA-5678895
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Gene expression (Transcription) R-HSA-74160
Signaling by ROBO receptors R-HSA-376176
Regulation of Apoptosis R-HSA-169911
UCH proteinases R-HSA-5689603
Cytokine Signaling in Immune system R-HSA-1280215
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
Hh mutants abrogate ligand secretion R-HSA-5387390
Synthesis of DNA R-HSA-69239
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of amino acids and derivatives R-HSA-71291
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Host Interactions of HIV factors R-HSA-162909
Nervous system development R-HSA-9675108
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Neddylation R-HSA-8951664
Negative regulation of NOTCH4 signaling R-HSA-9604323
MAPK6/MAPK4 signaling R-HSA-5687128
M Phase R-HSA-68886
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Dependent G1 DNA Damage Response R-HSA-69563
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI2 by the proteasome R-HSA-5610783
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
FCERI mediated NF-kB activation R-HSA-2871837
Programmed Cell Death R-HSA-5357801
DNA Replication R-HSA-69306
C-type lectin receptors (CLRs) R-HSA-5621481
Host Interactions of HIV factors R-HSA-162909
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCR signaling R-HSA-202403
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
Hedgehog 'on' state R-HSA-5632684
Mitotic Metaphase and Anaphase R-HSA-2555396
M Phase R-HSA-68886
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
Apoptosis R-HSA-109581
Disease R-HSA-1643685
Transcriptional regulation by RUNX3 R-HSA-8878159
Assembly of the pre-replicative complex R-HSA-68867
Deubiquitination R-HSA-5688426
Downstream TCR signaling R-HSA-202424
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Anaphase R-HSA-68882
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of DVL R-HSA-4641258
MAPK family signaling cascades R-HSA-5683057
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI1 by the proteasome R-HSA-5610780
RAF/MAP kinase cascade R-HSA-5673001
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle R-HSA-1640170
Metabolism of RNA R-HSA-8953854
Activation of NF-kappaB in B cells R-HSA-1169091
Hedgehog 'off' state R-HSA-5610787
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by NOTCH R-HSA-157118
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S DNA Damage Checkpoints R-HSA-69615
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Negative regulation of NOTCH4 signaling R-HSA-9604323
Neutrophil degranulation R-HSA-6798695
Gene expression (Transcription) R-HSA-74160
ABC transporter disorders R-HSA-5619084
Transport of small molecules R-HSA-382551
ER-Phagosome pathway R-HSA-1236974
Developmental Biology R-HSA-1266738
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Generic Transcription Pathway R-HSA-212436
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Interleukins R-HSA-449147
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
PIP3 activates AKT signaling R-HSA-1257604
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
Neddylation R-HSA-8951664
Vif-mediated degradation of APOBEC3G R-HSA-180585
Nervous system development R-HSA-9675108
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of proteins R-HSA-392499
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
Disorders of transmembrane transporters R-HSA-5619115
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle Checkpoints R-HSA-69620
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Cellular responses to stimuli R-HSA-8953897
Orc1 removal from chromatin R-HSA-68949
Metabolism of amino acids and derivatives R-HSA-71291
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle, Mitotic R-HSA-69278
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of polyamines R-HSA-351202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants are degraded by ERAD R-HSA-5362768
HIV Infection R-HSA-162906
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RAS by GAPs R-HSA-5658442
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
Cellular response to hypoxia R-HSA-1234174
Cellular response to chemical stress R-HSA-9711123
S Phase R-HSA-69242
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
Adaptive Immune System R-HSA-1280218
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Post-translational protein modification R-HSA-597592
Cellular responses to stress R-HSA-2262752
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S Transition R-HSA-69206
Synthesis of DNA R-HSA-69239
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Class I MHC mediated antigen processing & presentation R-HSA-983169
Intracellular signaling by second messengers R-HSA-9006925
PCP/CE pathway R-HSA-4086400
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by ROBO receptors R-HSA-376176
Mitotic G2-G2/M phases R-HSA-453274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH4 R-HSA-9013694
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mitotic cell cycle R-HSA-453276
Orc1 removal from chromatin R-HSA-68949
Vif-mediated degradation of APOBEC3G R-HSA-180585
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'on' state R-HSA-5632684
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Innate Immune System R-HSA-168249
Degradation of DVL R-HSA-4641258
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Cell Cycle, Mitotic R-HSA-69278
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by the B Cell Receptor (BCR) R-HSA-983705
KEAP1-NFE2L2 pathway R-HSA-9755511
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI2 by the proteasome R-HSA-5610783
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
Infectious disease R-HSA-5663205
Mitotic Metaphase and Anaphase R-HSA-2555396
DNA Replication Pre-Initiation R-HSA-69002
Class I MHC mediated antigen processing & presentation R-HSA-983169
Gene expression (Transcription) R-HSA-74160
Regulation of Apoptosis R-HSA-169911
Cellular response to chemical stress R-HSA-9711123
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Asymmetric localization of PCP proteins R-HSA-4608870
Neutrophil degranulation R-HSA-6798695
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ER-Phagosome pathway R-HSA-1236974
Signal Transduction R-HSA-162582
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by ROBO receptors R-HSA-376176
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RNA Polymerase II Transcription R-HSA-73857
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
TCR signaling R-HSA-202403
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX1 R-HSA-8878171
Intracellular signaling by second messengers R-HSA-9006925
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of proteins R-HSA-392499
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX3 expression and activity R-HSA-8941858
p53-Dependent G1 DNA Damage Response R-HSA-69563
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Independent DNA Damage Response R-HSA-69610
G1/S DNA Damage Checkpoints R-HSA-69615
Deubiquitination R-HSA-5688426
M Phase R-HSA-68886
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
Generic Transcription Pathway R-HSA-212436
Downstream TCR signaling R-HSA-202424
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Vpu mediated degradation of CD4 R-HSA-180534
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'off' state R-HSA-5610787
Nervous system development R-HSA-9675108
Cellular responses to stimuli R-HSA-8953897
Hedgehog ligand biogenesis R-HSA-5358346
Interleukin-1 signaling R-HSA-9020702
Separation of Sister Chromatids R-HSA-2467813
MAPK1/MAPK3 signaling R-HSA-5684996
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of GLI1 by the proteasome R-HSA-5610780
Mitotic G2-G2/M phases R-HSA-453274
UCH proteinases R-HSA-5689603
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of RNA R-HSA-8953854
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Stabilization of p53 R-HSA-69541
Regulation of RUNX2 expression and activity R-HSA-8939902
Programmed Cell Death R-HSA-5357801
Cell Cycle R-HSA-1640170
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cytokine Signaling in Immune system R-HSA-1280215
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
G2/M Transition R-HSA-69275
Disease R-HSA-1643685
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1/S Transition R-HSA-69206
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC-family proteins mediated transport R-HSA-382556
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic G1 phase and G1/S transition R-HSA-453279
Ub-specific processing proteases R-HSA-5689880
Disorders of transmembrane transporters R-HSA-5619115
Signaling by WNT R-HSA-195721
DNA Replication R-HSA-69306
ABC transporter disorders R-HSA-5619084
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to hypoxia R-HSA-1234174
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
Synthesis of DNA R-HSA-69239
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PCP/CE pathway R-HSA-4086400
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Interleukin-1 family signaling R-HSA-446652
Disorders of transmembrane transporters R-HSA-5619115
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
Mitotic Anaphase R-HSA-68882
Hh mutants are degraded by ERAD R-HSA-5362768
Adaptive Immune System R-HSA-1280218
MAPK6/MAPK4 signaling R-HSA-5687128
Asymmetric localization of PCP proteins R-HSA-4608870
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of AXIN R-HSA-4641257
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Defective CFTR causes cystic fibrosis R-HSA-5678895
HIV Infection R-HSA-162906
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
DNA Replication R-HSA-69306
Cellular responses to stimuli R-HSA-8953897
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of polyamines R-HSA-351202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
ABC-family proteins mediated transport R-HSA-382556
Activation of NF-kappaB in B cells R-HSA-1169091
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Developmental Biology R-HSA-1266738
Deubiquitination R-HSA-5688426
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by ROBO receptors R-HSA-376176
Separation of Sister Chromatids R-HSA-2467813
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by NOTCH R-HSA-157118
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Programmed Cell Death R-HSA-5357801
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
Class I MHC mediated antigen processing & presentation R-HSA-983169
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RUNX3 expression and activity R-HSA-8941858
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 signaling R-HSA-9020702
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated NF-kB activation R-HSA-2871837
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Generic Transcription Pathway R-HSA-212436
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Signaling by Interleukins R-HSA-449147
MAPK family signaling cascades R-HSA-5683057
Degradation of DVL R-HSA-4641258
Beta-catenin independent WNT signaling R-HSA-3858494
Innate Immune System R-HSA-168249
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Apoptosis R-HSA-109581
Intracellular signaling by second messengers R-HSA-9006925
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vpu mediated degradation of CD4 R-HSA-180534
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH4 R-HSA-9013694
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
RNA Polymerase II Transcription R-HSA-73857
Assembly of the pre-replicative complex R-HSA-68867
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Transition R-HSA-69275
Gene expression (Transcription) R-HSA-74160
Mitotic G1 phase and G1/S transition R-HSA-453279
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Synthesis of DNA R-HSA-69239
Cellular response to chemical stress R-HSA-9711123
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Axon guidance R-HSA-422475
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of Apoptosis R-HSA-169911
Immune System R-HSA-168256
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC transporter disorders R-HSA-5619084
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by WNT R-HSA-195721
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Hedgehog R-HSA-5358351
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Neddylation R-HSA-8951664
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Orc1 removal from chromatin R-HSA-68949
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
Stabilization of p53 R-HSA-69541
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
PIP3 activates AKT signaling R-HSA-1257604
G1/S DNA Damage Checkpoints R-HSA-69615
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog ligand biogenesis R-HSA-5358346
PCP/CE pathway R-HSA-4086400
Neutrophil degranulation R-HSA-6798695
Hedgehog 'on' state R-HSA-5632684
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Disease R-HSA-1643685
PTEN Regulation R-HSA-6807070
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S Transition R-HSA-69206
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of amino acids and derivatives R-HSA-71291
UCH proteinases R-HSA-5689603
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Switching of origins to a post-replicative state R-HSA-69052
Downstream TCR signaling R-HSA-202424
Cell Cycle Checkpoints R-HSA-69620
Post-translational protein modification R-HSA-597592
M Phase R-HSA-68886
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle R-HSA-1640170
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Neddylation R-HSA-8951664
Switching of origins to a post-replicative state R-HSA-69052
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle Checkpoints R-HSA-69620
ABC-family proteins mediated transport R-HSA-382556
Neutrophil degranulation R-HSA-6798695
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hh mutants are degraded by ERAD R-HSA-5362768
HIV Infection R-HSA-162906
Hedgehog 'on' state R-HSA-5632684
Mitotic G2-G2/M phases R-HSA-453274
Degradation of beta-catenin by the destruction complex R-HSA-195253
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 signaling R-HSA-9020702
Degradation of AXIN R-HSA-4641257
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of GLI2 by the proteasome R-HSA-5610783
Downstream TCR signaling R-HSA-202424
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle R-HSA-1640170
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
DNA Replication R-HSA-69306
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'off' state R-HSA-5610787
Regulation of Apoptosis R-HSA-169911
Generic Transcription Pathway R-HSA-212436
Programmed Cell Death R-HSA-5357801
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to chemical stress R-HSA-9711123
Intracellular signaling by second messengers R-HSA-9006925
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
Signal Transduction R-HSA-162582
Regulation of expression of SLITs and ROBOs R-HSA-9010553
UCH proteinases R-HSA-5689603
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Adaptive Immune System R-HSA-1280218
PTEN Regulation R-HSA-6807070
Degradation of GLI1 by the proteasome R-HSA-5610780
M Phase R-HSA-68886
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX3 R-HSA-8878159
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Disease R-HSA-1643685
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic Metaphase and Anaphase R-HSA-2555396
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of mitotic cell cycle R-HSA-453276
p53-Independent DNA Damage Response R-HSA-69610
Nervous system development R-HSA-9675108
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TCR signaling R-HSA-202403
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ER-Phagosome pathway R-HSA-1236974
Orc1 removal from chromatin R-HSA-68949
Cytokine Signaling in Immune system R-HSA-1280215
MAPK family signaling cascades R-HSA-5683057
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Nuclear events mediated by NFE2L2 R-HSA-9759194
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ub-specific processing proteases R-HSA-5689880
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Interleukins R-HSA-449147
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Developmental Biology R-HSA-1266738
Immune System R-HSA-168256
Disorders of transmembrane transporters R-HSA-5619115
Cyclin E associated events during G1/S transition R-HSA-69202
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic Anaphase R-HSA-68882
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants abrogate ligand secretion R-HSA-5387390
Deubiquitination R-HSA-5688426
PIP3 activates AKT signaling R-HSA-1257604
Host Interactions of HIV factors R-HSA-162909
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC transporter disorders R-HSA-5619084
Signaling by WNT R-HSA-195721
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX2 expression and activity R-HSA-8939902
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RAS by GAPs R-HSA-5658442
Innate Immune System R-HSA-168249
CLEC7A (Dectin-1) signaling R-HSA-5607764
G2/M Checkpoints R-HSA-69481
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by ROBO receptors R-HSA-376176
Signaling by NOTCH4 R-HSA-9013694
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
S Phase R-HSA-69242
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Post-translational protein modification R-HSA-597592
Synthesis of DNA R-HSA-69239
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
Cellular responses to stress R-HSA-2262752
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular responses to stimuli R-HSA-8953897
G2/M Transition R-HSA-69275
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Asymmetric localization of PCP proteins R-HSA-4608870
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of polyamines R-HSA-351202
Transport of small molecules R-HSA-382551
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S Transition R-HSA-69206
Gene expression (Transcription) R-HSA-74160
Interleukin-1 family signaling R-HSA-446652
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Assembly of the pre-replicative complex R-HSA-68867
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RNA Polymerase II Transcription R-HSA-73857
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Axon guidance R-HSA-422475
Apoptosis R-HSA-109581
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of RNA R-HSA-8953854
Metabolism of proteins R-HSA-392499
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX3 expression and activity R-HSA-8941858
Programmed Cell Death R-HSA-5357801
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of AXIN R-HSA-4641257
Axon guidance R-HSA-422475
Hedgehog 'on' state R-HSA-5632684
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of RUNX2 expression and activity R-HSA-8939902
Generic Transcription Pathway R-HSA-212436
Downstream TCR signaling R-HSA-202424
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by Hedgehog R-HSA-5358351
p53-Independent DNA Damage Response R-HSA-69610
Gene expression (Transcription) R-HSA-74160
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH4 R-HSA-9013694
ER-Phagosome pathway R-HSA-1236974
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI1 by the proteasome R-HSA-5610780
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
FCERI mediated NF-kB activation R-HSA-2871837
Class I MHC mediated antigen processing & presentation R-HSA-983169
Assembly of the pre-replicative complex R-HSA-68867
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Disorders of transmembrane transporters R-HSA-5619115
Negative regulation of NOTCH4 signaling R-HSA-9604323
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Adaptive Immune System R-HSA-1280218
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Activation of NF-kappaB in B cells R-HSA-1169091
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Post-translational protein modification R-HSA-597592
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Nuclear events mediated by NFE2L2 R-HSA-9759194
DNA Replication R-HSA-69306
Infectious disease R-HSA-5663205
HIV Infection R-HSA-162906
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX1 R-HSA-8878171
C-type lectin receptors (CLRs) R-HSA-5621481
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle, Mitotic R-HSA-69278
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'off' state R-HSA-5610787
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of DVL R-HSA-4641258
Signaling by WNT R-HSA-195721
Ub-specific processing proteases R-HSA-5689880
Neddylation R-HSA-8951664
Apoptosis R-HSA-109581
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
ABC transporter disorders R-HSA-5619084
Interleukin-1 signaling R-HSA-9020702
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Transition R-HSA-69275
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stimuli R-HSA-8953897
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
ABC-family proteins mediated transport R-HSA-382556
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by Interleukins R-HSA-449147
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
TCF dependent signaling in response to WNT R-HSA-201681
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Developmental Biology R-HSA-1266738
G2/M Checkpoints R-HSA-69481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RAS by GAPs R-HSA-5658442
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle R-HSA-1640170
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle Checkpoints R-HSA-69620
Neutrophil degranulation R-HSA-6798695
Metabolism R-HSA-1430728
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by ROBO receptors R-HSA-376176
Antigen processing-Cross presentation R-HSA-1236975
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
M Phase R-HSA-68886
Intracellular signaling by second messengers R-HSA-9006925
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Regulation of Apoptosis R-HSA-169911
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Anaphase R-HSA-68882
Regulation of PTEN stability and activity R-HSA-8948751
Switching of origins to a post-replicative state R-HSA-69052
Immune System R-HSA-168256
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
TCR signaling R-HSA-202403
Synthesis of DNA R-HSA-69239
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic Metaphase and Anaphase R-HSA-2555396
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX3 R-HSA-8878159
Host Interactions of HIV factors R-HSA-162909
Disease R-HSA-1643685
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vpu mediated degradation of CD4 R-HSA-180534
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nervous system development R-HSA-9675108
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G1/S Transition R-HSA-69206
Metabolism of polyamines R-HSA-351202
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of RNA R-HSA-8953854
Signaling by WNT R-HSA-195721
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of GLI2 by the proteasome R-HSA-5610783
Nervous system development R-HSA-9675108
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of amino acids and derivatives R-HSA-71291
TCR signaling R-HSA-202403
Synthesis of DNA R-HSA-69239
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
MAPK family signaling cascades R-HSA-5683057
Degradation of DVL R-HSA-4641258
Adaptive Immune System R-HSA-1280218
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
FCERI mediated NF-kB activation R-HSA-2871837
Activation of NF-kappaB in B cells R-HSA-1169091
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Axon guidance R-HSA-422475
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle, Mitotic R-HSA-69278
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Innate Immune System R-HSA-168249
Regulation of Apoptosis R-HSA-169911
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX3 R-HSA-8878159
Intracellular signaling by second messengers R-HSA-9006925
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of PTEN stability and activity R-HSA-8948751
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
Transport of small molecules R-HSA-382551
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
Deubiquitination R-HSA-5688426
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of RUNX2 expression and activity R-HSA-8939902
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Switching of origins to a post-replicative state R-HSA-69052
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
Separation of Sister Chromatids R-HSA-2467813
Defective CFTR causes cystic fibrosis R-HSA-5678895
Class I MHC mediated antigen processing & presentation R-HSA-983169
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Signaling by Interleukins R-HSA-449147
Signaling by ROBO receptors R-HSA-376176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PCP/CE pathway R-HSA-4086400
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog 'on' state R-HSA-5632684
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Neddylation R-HSA-8951664
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Gene expression (Transcription) R-HSA-74160
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
Ub-specific processing proteases R-HSA-5689880
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
HIV Infection R-HSA-162906
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Dependent G1 DNA Damage Response R-HSA-69563
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Neutrophil degranulation R-HSA-6798695
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Vif-mediated degradation of APOBEC3G R-HSA-180585
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent DNA Damage Response R-HSA-69610
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Cell Cycle Checkpoints R-HSA-69620
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Generic Transcription Pathway R-HSA-212436
Mitotic Metaphase and Anaphase R-HSA-2555396
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stimuli R-HSA-8953897
C-type lectin receptors (CLRs) R-HSA-5621481
S Phase R-HSA-69242
M Phase R-HSA-68886
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Mitotic Anaphase R-HSA-68882
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to hypoxia R-HSA-1234174
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
G2/M Checkpoints R-HSA-69481
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Cellular response to chemical stress R-HSA-9711123
Disease R-HSA-1643685
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic G1 phase and G1/S transition R-HSA-453279
Antigen processing-Cross presentation R-HSA-1236975
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
Vpu mediated degradation of CD4 R-HSA-180534
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of AXIN R-HSA-4641257
Metabolism R-HSA-1430728
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Generic Transcription Pathway R-HSA-212436
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle R-HSA-1640170
C-type lectin receptors (CLRs) R-HSA-5621481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog ligand biogenesis R-HSA-5358346
Apoptosis R-HSA-109581
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of PTEN stability and activity R-HSA-8948751
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Stabilization of p53 R-HSA-69541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ub-specific processing proteases R-HSA-5689880
G2/M Checkpoints R-HSA-69481
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by Hedgehog R-HSA-5358351
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cellular response to hypoxia R-HSA-1234174
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by NOTCH4 R-HSA-9013694
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
G2/M Transition R-HSA-69275
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC-family proteins mediated transport R-HSA-382556
Immune System R-HSA-168256
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
NIK-->noncanonical NF-kB signaling R-HSA-5676590
DNA Replication Pre-Initiation R-HSA-69002
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
S Phase R-HSA-69242
Transport of small molecules R-HSA-382551
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Deubiquitination R-HSA-5688426
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
Neddylation R-HSA-8951664
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stress R-HSA-2262752
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PTEN Regulation R-HSA-6807070
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle Checkpoints R-HSA-69620
Beta-catenin independent WNT signaling R-HSA-3858494
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Cyclin E associated events during G1/S transition R-HSA-69202
Axon guidance R-HSA-422475
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of Apoptosis R-HSA-169911
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of RNA R-HSA-8953854
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic Anaphase R-HSA-68882
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of polyamines R-HSA-351202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
HIV Infection R-HSA-162906
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Independent DNA Damage Response R-HSA-69610
PCP/CE pathway R-HSA-4086400
Nervous system development R-HSA-9675108
TCF dependent signaling in response to WNT R-HSA-201681
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Synthesis of DNA R-HSA-69239
Interleukin-1 family signaling R-HSA-446652
Signaling by ROBO receptors R-HSA-376176
M Phase R-HSA-68886
Hh mutants are degraded by ERAD R-HSA-5362768
Assembly of the pre-replicative complex R-HSA-68867
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
ABC transporter disorders R-HSA-5619084
Hedgehog 'off' state R-HSA-5610787
PIP3 activates AKT signaling R-HSA-1257604
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle, Mitotic R-HSA-69278
Adaptive Immune System R-HSA-1280218
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Cellular responses to stimuli R-HSA-8953897
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Dependent G1 DNA Damage Response R-HSA-69563
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Neutrophil degranulation R-HSA-6798695
Orc1 removal from chromatin R-HSA-68949
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hh mutants abrogate ligand secretion R-HSA-5387390
Signal Transduction R-HSA-162582
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication R-HSA-69306
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK6/MAPK4 signaling R-HSA-5687128
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI1 by the proteasome R-HSA-5610780
MAPK family signaling cascades R-HSA-5683057
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ub-specific processing proteases R-HSA-5689880
M Phase R-HSA-68886
Transcriptional regulation by RUNX3 R-HSA-8878159
Neddylation R-HSA-8951664
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of AXIN R-HSA-4641257
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream TCR signaling R-HSA-202424
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by ROBO receptors R-HSA-376176
Metabolism of proteins R-HSA-392499
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic Anaphase R-HSA-68882
Hh mutants are degraded by ERAD R-HSA-5362768
ABC transporter disorders R-HSA-5619084
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by WNT R-HSA-195721
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing-Cross presentation R-HSA-1236975
PTEN Regulation R-HSA-6807070
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of DVL R-HSA-4641258
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cell Cycle, Mitotic R-HSA-69278
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by NOTCH R-HSA-157118
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
p53-Independent DNA Damage Response R-HSA-69610
Cyclin E associated events during G1/S transition R-HSA-69202
ER-Phagosome pathway R-HSA-1236974
Neutrophil degranulation R-HSA-6798695
KEAP1-NFE2L2 pathway R-HSA-9755511
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G2/M Checkpoints R-HSA-69481
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of amino acids and derivatives R-HSA-71291
TCF dependent signaling in response to WNT R-HSA-201681
TCR signaling R-HSA-202403
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
Stabilization of p53 R-HSA-69541
PCP/CE pathway R-HSA-4086400
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
Orc1 removal from chromatin R-HSA-68949
Gene expression (Transcription) R-HSA-74160
Adaptive Immune System R-HSA-1280218
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Interleukin-1 signaling R-HSA-9020702
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G2-G2/M phases R-HSA-453274
UCH proteinases R-HSA-5689603
Innate Immune System R-HSA-168249
Separation of Sister Chromatids R-HSA-2467813
S Phase R-HSA-69242
Beta-catenin independent WNT signaling R-HSA-3858494
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Host Interactions of HIV factors R-HSA-162909
Transport of small molecules R-HSA-382551
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Vif-mediated degradation of APOBEC3G R-HSA-180585
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of beta-catenin by the destruction complex R-HSA-195253
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
RNA Polymerase II Transcription R-HSA-73857
Cellular response to hypoxia R-HSA-1234174
Assembly of the pre-replicative complex R-HSA-68867
Post-translational protein modification R-HSA-597592
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular response to chemical stress R-HSA-9711123
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stimuli R-HSA-8953897
Signaling by Interleukins R-HSA-449147
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK6/MAPK4 signaling R-HSA-5687128
Disease R-HSA-1643685
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by Hedgehog R-HSA-5358351
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle R-HSA-1640170
Deubiquitination R-HSA-5688426
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Axon guidance R-HSA-422475
ABC-family proteins mediated transport R-HSA-382556
Metabolism of RNA R-HSA-8953854
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Interleukin-1 family signaling R-HSA-446652
Hedgehog 'off' state R-HSA-5610787
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stress R-HSA-2262752
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
DNA Replication R-HSA-69306
Nuclear events mediated by NFE2L2 R-HSA-9759194
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Disorders of transmembrane transporters R-HSA-5619115
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G1/S Transition R-HSA-69206
Regulation of mitotic cell cycle R-HSA-453276
Regulation of RUNX3 expression and activity R-HSA-8941858
HIV Infection R-HSA-162906
Immune System R-HSA-168256
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism R-HSA-1430728
Orc1 removal from chromatin R-HSA-68949
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX1 R-HSA-8878171
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
Mitotic Metaphase and Anaphase R-HSA-2555396
Class I MHC mediated antigen processing & presentation R-HSA-983169
Stabilization of p53 R-HSA-69541
Synthesis of DNA R-HSA-69239
Apoptosis R-HSA-109581
Assembly of the pre-replicative complex R-HSA-68867
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic Anaphase R-HSA-68882
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle, Mitotic R-HSA-69278
Cyclin E associated events during G1/S transition R-HSA-69202
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing-Cross presentation R-HSA-1236975
Metabolism R-HSA-1430728
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX2 expression and activity R-HSA-8939902
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
Nervous system development R-HSA-9675108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle Checkpoints R-HSA-69620
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'on' state R-HSA-5632684
Neddylation R-HSA-8951664
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G1 phase and G1/S transition R-HSA-453279
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Infectious disease R-HSA-5663205
Programmed Cell Death R-HSA-5357801
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Disease R-HSA-1643685
Hedgehog 'off' state R-HSA-5610787
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PCP/CE pathway R-HSA-4086400
UCH proteinases R-HSA-5689603
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transcriptional regulation by RUNX2 R-HSA-8878166
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of DVL R-HSA-4641258
Degradation of GLI2 by the proteasome R-HSA-5610783
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G2/M Transition R-HSA-69275
Generic Transcription Pathway R-HSA-212436
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream TCR signaling R-HSA-202424
MAPK family signaling cascades R-HSA-5683057
Signaling by ROBO receptors R-HSA-376176
Separation of Sister Chromatids R-HSA-2467813
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
DNA Replication R-HSA-69306
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
S Phase R-HSA-69242
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Gene expression (Transcription) R-HSA-74160
Degradation of AXIN R-HSA-4641257
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by NOTCH R-HSA-157118
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stress R-HSA-2262752
ER-Phagosome pathway R-HSA-1236974
TCR signaling R-HSA-202403
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Axon guidance R-HSA-422475
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of RNA R-HSA-8953854
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
Cell Cycle R-HSA-1640170
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of beta-catenin by the destruction complex R-HSA-195253
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Interleukin-1 signaling R-HSA-9020702
HIV Infection R-HSA-162906
Cellular responses to stimuli R-HSA-8953897
Hedgehog ligand biogenesis R-HSA-5358346
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of PTEN stability and activity R-HSA-8948751
ABC transporter disorders R-HSA-5619084
Intracellular signaling by second messengers R-HSA-9006925
PTEN Regulation R-HSA-6807070
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Host Interactions of HIV factors R-HSA-162909
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neutrophil degranulation R-HSA-6798695
Transcriptional regulation by RUNX3 R-HSA-8878159
Signal Transduction R-HSA-162582
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of polyamines R-HSA-351202
Metabolism of proteins R-HSA-392499
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Adaptive Immune System R-HSA-1280218
Deubiquitination R-HSA-5688426
G1/S DNA Damage Checkpoints R-HSA-69615
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1 DNA Damage Response R-HSA-69563
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH4 R-HSA-9013694
Cytokine Signaling in Immune system R-HSA-1280215
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Cellular responses to stress R-HSA-2262752
Neddylation R-HSA-8951664
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Class I MHC mediated antigen processing & presentation R-HSA-983169
TCR signaling R-HSA-202403
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by ROBO receptors R-HSA-376176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
Hedgehog 'on' state R-HSA-5632684
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by NOTCH R-HSA-157118
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Synthesis of DNA R-HSA-69239
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Neutrophil degranulation R-HSA-6798695
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
Adaptive Immune System R-HSA-1280218
Signaling by the B Cell Receptor (BCR) R-HSA-983705
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Degradation of GLI1 by the proteasome R-HSA-5610780
ABC-family proteins mediated transport R-HSA-382556
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Host Interactions of HIV factors R-HSA-162909
FCERI mediated NF-kB activation R-HSA-2871837
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
Developmental Biology R-HSA-1266738
Metabolism of RNA R-HSA-8953854
UCH proteinases R-HSA-5689603
Cytokine Signaling in Immune system R-HSA-1280215
Vpu mediated degradation of CD4 R-HSA-180534
RNA Polymerase II Transcription R-HSA-73857
Signaling by NOTCH4 R-HSA-9013694
Innate Immune System R-HSA-168249
PIP3 activates AKT signaling R-HSA-1257604
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Gene expression (Transcription) R-HSA-74160
Transport of small molecules R-HSA-382551
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle Checkpoints R-HSA-69620
Hh mutants are degraded by ERAD R-HSA-5362768
M Phase R-HSA-68886
Interleukin-1 family signaling R-HSA-446652
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK family signaling cascades R-HSA-5683057
PCP/CE pathway R-HSA-4086400
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of DVL R-HSA-4641258
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of polyamines R-HSA-351202
G2/M Checkpoints R-HSA-69481
C-type lectin receptors (CLRs) R-HSA-5621481
ABC transporter disorders R-HSA-5619084
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ub-specific processing proteases R-HSA-5689880
Hedgehog 'off' state R-HSA-5610787
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RAS by GAPs R-HSA-5658442
Stabilization of p53 R-HSA-69541
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Independent DNA Damage Response R-HSA-69610
Beta-catenin independent WNT signaling R-HSA-3858494
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Immune System R-HSA-168256
TCF dependent signaling in response to WNT R-HSA-201681
Cellular response to chemical stress R-HSA-9711123
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Axon guidance R-HSA-422475
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic Anaphase R-HSA-68882
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
Cell Cycle R-HSA-1640170
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transcriptional regulation by RUNX3 R-HSA-8878159
Generic Transcription Pathway R-HSA-212436
Activation of NF-kappaB in B cells R-HSA-1169091
S Phase R-HSA-69242
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Programmed Cell Death R-HSA-5357801
Intracellular signaling by second messengers R-HSA-9006925
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
Nervous system development R-HSA-9675108
Downstream TCR signaling R-HSA-202424
Post-translational protein modification R-HSA-597592
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism R-HSA-1430728
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
HIV Infection R-HSA-162906
Cellular response to hypoxia R-HSA-1234174
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
KEAP1-NFE2L2 pathway R-HSA-9755511
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vif-mediated degradation of APOBEC3G R-HSA-180585
Assembly of the pre-replicative complex R-HSA-68867
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hedgehog ligand biogenesis R-HSA-5358346
G1/S Transition R-HSA-69206
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of PTEN stability and activity R-HSA-8948751
PTEN Regulation R-HSA-6807070
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by WNT R-HSA-195721
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent G1/S DNA damage checkpoint R-HSA-69613

Expression Atlas ENSG00000108671
NCBI gene (formerly Entrezgene) 5717
GeneCards 9556
HGNC Symbol HGNC:9556
MIM gene 604449
UniProtKB Gene Name O00231
WikiGene 5717
Gene: PSMC3
Ensembl ID : ENSG00000165916
Description: proteasome 26S subunit, ATPase 3
Gene Synonyms: RPT5,TBP-1,TBP1
5 APIs:
218 Possible Orthologues:

Mitotic Anaphase R-HSA-68882
Apoptosis R-HSA-109581
Infectious disease R-HSA-5663205
G2/M Checkpoints R-HSA-69481
Hh mutants are degraded by ERAD R-HSA-5362768
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX2 R-HSA-8878166
Orc1 removal from chromatin R-HSA-68949
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Independent DNA Damage Response R-HSA-69610
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Innate Immune System R-HSA-168249
Negative regulation of NOTCH4 signaling R-HSA-9604323
S Phase R-HSA-69242
Cell Cycle, Mitotic R-HSA-69278
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic G2-G2/M phases R-HSA-453274
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog 'off' state R-HSA-5610787
p53-Dependent G1 DNA Damage Response R-HSA-69563
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
UCH proteinases R-HSA-5689603
Neutrophil degranulation R-HSA-6798695
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 signaling R-HSA-9020702
ABC transporter disorders R-HSA-5619084
Regulation of RAS by GAPs R-HSA-5658442
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Developmental Biology R-HSA-1266738
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of GLI1 by the proteasome R-HSA-5610780
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism R-HSA-1430728
Downstream TCR signaling R-HSA-202424
G1/S DNA Damage Checkpoints R-HSA-69615
FCERI mediated NF-kB activation R-HSA-2871837
G1/S Transition R-HSA-69206
Separation of Sister Chromatids R-HSA-2467813
MAPK6/MAPK4 signaling R-HSA-5687128
Post-translational protein modification R-HSA-597592
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of RNA R-HSA-8953854
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of AXIN R-HSA-4641257
Cellular responses to stimuli R-HSA-8953897
PTEN Regulation R-HSA-6807070
Disorders of transmembrane transporters R-HSA-5619115
M Phase R-HSA-68886
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Vpu mediated degradation of CD4 R-HSA-180534
Cellular response to hypoxia R-HSA-1234174
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PCP/CE pathway R-HSA-4086400
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
Axon guidance R-HSA-422475
Degradation of GLI2 by the proteasome R-HSA-5610783
Mitotic G1 phase and G1/S transition R-HSA-453279
HIV Infection R-HSA-162906
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of Apoptosis R-HSA-169911
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PIP3 activates AKT signaling R-HSA-1257604
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of NF-kappaB in B cells R-HSA-1169091
Hh mutants abrogate ligand secretion R-HSA-5387390
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by ROBO receptors R-HSA-376176
Cyclin E associated events during G1/S transition R-HSA-69202
Adaptive Immune System R-HSA-1280218
Hedgehog 'on' state R-HSA-5632684
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
KEAP1-NFE2L2 pathway R-HSA-9755511
Nuclear events mediated by NFE2L2 R-HSA-9759194
RAF/MAP kinase cascade R-HSA-5673001
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Switching of origins to a post-replicative state R-HSA-69052
Assembly of the pre-replicative complex R-HSA-68867
Signaling by Hedgehog R-HSA-5358351
DNA Replication R-HSA-69306
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Synthesis of DNA R-HSA-69239
Immune System R-HSA-168256
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Transition R-HSA-69275
ABC-family proteins mediated transport R-HSA-382556
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nervous system development R-HSA-9675108
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
DNA Replication Pre-Initiation R-HSA-69002
Transport of small molecules R-HSA-382551
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX1 R-HSA-8878171
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stimuli R-HSA-8953897
Signaling by ROBO receptors R-HSA-376176
Post-translational protein modification R-HSA-597592
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH4 R-HSA-9013694
DNA Replication R-HSA-69306
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Regulation of Apoptosis R-HSA-169911
RNA Polymerase II Transcription R-HSA-73857
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of DVL R-HSA-4641258
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G2-G2/M phases R-HSA-453274
Transcriptional regulation by RUNX1 R-HSA-8878171
UCH proteinases R-HSA-5689603
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX2 expression and activity R-HSA-8939902
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Axon guidance R-HSA-422475
G1/S DNA Damage Checkpoints R-HSA-69615
Neutrophil degranulation R-HSA-6798695
Disorders of transmembrane transporters R-HSA-5619115
TCR signaling R-HSA-202403
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
ABC transporter disorders R-HSA-5619084
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
PCP/CE pathway R-HSA-4086400
Switching of origins to a post-replicative state R-HSA-69052
Deubiquitination R-HSA-5688426
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Beta-catenin independent WNT signaling R-HSA-3858494
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transport of small molecules R-HSA-382551
Neddylation R-HSA-8951664
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
ABC-family proteins mediated transport R-HSA-382556
Downstream TCR signaling R-HSA-202424
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants are degraded by ERAD R-HSA-5362768
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RAF/MAP kinase cascade R-HSA-5673001
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stress R-HSA-2262752
Interleukin-1 signaling R-HSA-9020702
MAPK6/MAPK4 signaling R-HSA-5687128
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of polyamines R-HSA-351202
Apoptosis R-HSA-109581
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Immune System R-HSA-168256
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
MAPK family signaling cascades R-HSA-5683057
Disease R-HSA-1643685
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Mitotic Anaphase R-HSA-68882
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 family signaling R-HSA-446652
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH R-HSA-157118
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
M Phase R-HSA-68886
Regulation of PTEN stability and activity R-HSA-8948751
Ub-specific processing proteases R-HSA-5689880
Antigen processing-Cross presentation R-HSA-1236975
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
TCF dependent signaling in response to WNT R-HSA-201681
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of RNA R-HSA-8953854
Metabolism R-HSA-1430728
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by WNT R-HSA-195721
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'off' state R-HSA-5610787
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Class I MHC mediated antigen processing & presentation R-HSA-983169
ER-Phagosome pathway R-HSA-1236974
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
Stabilization of p53 R-HSA-69541
p53-Independent DNA Damage Response R-HSA-69610
Synthesis of DNA R-HSA-69239
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle, Mitotic R-HSA-69278
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of AXIN R-HSA-4641257
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Hedgehog R-HSA-5358351
Degradation of beta-catenin by the destruction complex R-HSA-195253
Generic Transcription Pathway R-HSA-212436
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
HIV Infection R-HSA-162906
Programmed Cell Death R-HSA-5357801
Negative regulation of NOTCH4 signaling R-HSA-9604323
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX3 R-HSA-8878159
Gene expression (Transcription) R-HSA-74160
Hh mutants abrogate ligand secretion R-HSA-5387390
Separation of Sister Chromatids R-HSA-2467813
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog 'on' state R-HSA-5632684
ER-Phagosome pathway R-HSA-1236974
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Generic Transcription Pathway R-HSA-212436
Degradation of GLI1 by the proteasome R-HSA-5610780
Mitotic Anaphase R-HSA-68882
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by Hedgehog R-HSA-5358351
Synthesis of DNA R-HSA-69239
RAF/MAP kinase cascade R-HSA-5673001
Disorders of transmembrane transporters R-HSA-5619115
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Developmental Biology R-HSA-1266738
Degradation of beta-catenin by the destruction complex R-HSA-195253
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PIP3 activates AKT signaling R-HSA-1257604
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transcriptional regulation by RUNX1 R-HSA-8878171
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular response to chemical stress R-HSA-9711123
Axon guidance R-HSA-422475
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Neddylation R-HSA-8951664
Mitotic G2-G2/M phases R-HSA-453274
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Infectious disease R-HSA-5663205
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Gene expression (Transcription) R-HSA-74160
Downstream TCR signaling R-HSA-202424
Class I MHC mediated antigen processing & presentation R-HSA-983169
Host Interactions of HIV factors R-HSA-162909
Intracellular signaling by second messengers R-HSA-9006925
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
PCP/CE pathway R-HSA-4086400
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular response to hypoxia R-HSA-1234174
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of Apoptosis R-HSA-169911
Metabolism of proteins R-HSA-392499
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism R-HSA-1430728
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S Transition R-HSA-69206
Signaling by NOTCH4 R-HSA-9013694
ABC transporter disorders R-HSA-5619084
Beta-catenin independent WNT signaling R-HSA-3858494
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RAS by GAPs R-HSA-5658442
Activation of NF-kappaB in B cells R-HSA-1169091
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
Assembly of the pre-replicative complex R-HSA-68867
Immune System R-HSA-168256
Transcriptional regulation by RUNX3 R-HSA-8878159
Hh mutants abrogate ligand secretion R-HSA-5387390
M Phase R-HSA-68886
Signaling by WNT R-HSA-195721
Deubiquitination R-HSA-5688426
Cellular responses to stimuli R-HSA-8953897
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
HIV Infection R-HSA-162906
Adaptive Immune System R-HSA-1280218
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
Hh mutants are degraded by ERAD R-HSA-5362768
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Nervous system development R-HSA-9675108
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of polyamines R-HSA-351202
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
Cytokine Signaling in Immune system R-HSA-1280215
UCH proteinases R-HSA-5689603
TCR signaling R-HSA-202403
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'on' state R-HSA-5632684
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of RUNX2 expression and activity R-HSA-8939902
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Vpu mediated degradation of CD4 R-HSA-180534
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Signaling by ROBO receptors R-HSA-376176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Interleukins R-HSA-449147
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle R-HSA-1640170
DNA Replication R-HSA-69306
Regulation of PTEN stability and activity R-HSA-8948751
MAPK1/MAPK3 signaling R-HSA-5684996
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Degradation of DVL R-HSA-4641258
Ub-specific processing proteases R-HSA-5689880
Hedgehog 'off' state R-HSA-5610787
Innate Immune System R-HSA-168249
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Neutrophil degranulation R-HSA-6798695
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK family signaling cascades R-HSA-5683057
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
G1/S DNA Damage Checkpoints R-HSA-69615
Disease R-HSA-1643685
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Cell Cycle Checkpoints R-HSA-69620
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Asymmetric localization of PCP proteins R-HSA-4608870
RNA Polymerase II Transcription R-HSA-73857
Orc1 removal from chromatin R-HSA-68949
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PTEN Regulation R-HSA-6807070
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of AXIN R-HSA-4641257
MAPK family signaling cascades R-HSA-5683057
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'off' state R-HSA-5610787
ABC-family proteins mediated transport R-HSA-382556
Signaling by NOTCH4 R-HSA-9013694
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hedgehog ligand biogenesis R-HSA-5358346
Disorders of transmembrane transporters R-HSA-5619115
Transcriptional regulation by RUNX1 R-HSA-8878171
Downstream TCR signaling R-HSA-202424
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Interleukin-1 signaling R-HSA-9020702
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Assembly of the pre-replicative complex R-HSA-68867
Intracellular signaling by second messengers R-HSA-9006925
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Hedgehog R-HSA-5358351
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX3 R-HSA-8878159
Developmental Biology R-HSA-1266738
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle Checkpoints R-HSA-69620
Cellular response to chemical stress R-HSA-9711123
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mitotic cell cycle R-HSA-453276
G1/S Transition R-HSA-69206
MAPK1/MAPK3 signaling R-HSA-5684996
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Neutrophil degranulation R-HSA-6798695
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
G2/M Transition R-HSA-69275
Hh mutants are degraded by ERAD R-HSA-5362768
Post-translational protein modification R-HSA-597592
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
C-type lectin receptors (CLRs) R-HSA-5621481
FCERI mediated NF-kB activation R-HSA-2871837
Synthesis of DNA R-HSA-69239
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Dependent G1 DNA Damage Response R-HSA-69563
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hh mutants abrogate ligand secretion R-HSA-5387390
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'on' state R-HSA-5632684
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
Interleukin-1 family signaling R-HSA-446652
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transport of small molecules R-HSA-382551
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of AXIN R-HSA-4641257
Cellular response to hypoxia R-HSA-1234174
p53-Independent DNA Damage Response R-HSA-69610
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Gene expression (Transcription) R-HSA-74160
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
Host Interactions of HIV factors R-HSA-162909
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of NF-kappaB in B cells R-HSA-1169091
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Switching of origins to a post-replicative state R-HSA-69052
Programmed Cell Death R-HSA-5357801
Metabolism of RNA R-HSA-8953854
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Signaling by the B Cell Receptor (BCR) R-HSA-983705
UCH proteinases R-HSA-5689603
Cell Cycle R-HSA-1640170
Cellular responses to stimuli R-HSA-8953897
Regulation of Apoptosis R-HSA-169911
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of RUNX3 expression and activity R-HSA-8941858
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Defective CFTR causes cystic fibrosis R-HSA-5678895
Orc1 removal from chromatin R-HSA-68949
Class I MHC mediated antigen processing & presentation R-HSA-983169
Stabilization of p53 R-HSA-69541
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of DVL R-HSA-4641258
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of polyamines R-HSA-351202
Apoptosis R-HSA-109581
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transcriptional regulation by RUNX2 R-HSA-8878166
ABC transporter disorders R-HSA-5619084
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Adaptive Immune System R-HSA-1280218
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI2 by the proteasome R-HSA-5610783
Cellular responses to stress R-HSA-2262752
HIV Infection R-HSA-162906
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G2/M Checkpoints R-HSA-69481
Signaling by WNT R-HSA-195721
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
Separation of Sister Chromatids R-HSA-2467813
Antigen processing-Cross presentation R-HSA-1236975
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication Pre-Initiation R-HSA-69002
PCP/CE pathway R-HSA-4086400
Nuclear events mediated by NFE2L2 R-HSA-9759194
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of polyamines R-HSA-351202
Intracellular signaling by second messengers R-HSA-9006925
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of AXIN R-HSA-4641257
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Neutrophil degranulation R-HSA-6798695
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
Generic Transcription Pathway R-HSA-212436
ER-Phagosome pathway R-HSA-1236974
Disorders of transmembrane transporters R-HSA-5619115
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Gene expression (Transcription) R-HSA-74160
Degradation of beta-catenin by the destruction complex R-HSA-195253
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transport of small molecules R-HSA-382551
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism of amino acids and derivatives R-HSA-71291
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RAS by GAPs R-HSA-5658442
Signaling by ROBO receptors R-HSA-376176
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by Interleukins R-HSA-449147
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Signaling by WNT R-HSA-195721
RNA Polymerase II Transcription R-HSA-73857
Programmed Cell Death R-HSA-5357801
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signal Transduction R-HSA-162582
Switching of origins to a post-replicative state R-HSA-69052
TCF dependent signaling in response to WNT R-HSA-201681
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FCERI mediated NF-kB activation R-HSA-2871837
TCR signaling R-HSA-202403
G2/M Checkpoints R-HSA-69481
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
S Phase R-HSA-69242
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'on' state R-HSA-5632684
PCP/CE pathway R-HSA-4086400
Negative regulation of NOTCH4 signaling R-HSA-9604323
HIV Infection R-HSA-162906
DNA Replication R-HSA-69306
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle, Mitotic R-HSA-69278
Signaling by Hedgehog R-HSA-5358351
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RUNX3 expression and activity R-HSA-8941858
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
M Phase R-HSA-68886
Adaptive Immune System R-HSA-1280218
Cell Cycle R-HSA-1640170
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI2 by the proteasome R-HSA-5610783
Infectious disease R-HSA-5663205
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
Assembly of the pre-replicative complex R-HSA-68867
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transcriptional regulation by RUNX3 R-HSA-8878159
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC transporter disorders R-HSA-5619084
Interleukin-1 family signaling R-HSA-446652
Mitotic G2-G2/M phases R-HSA-453274
Activation of NF-kappaB in B cells R-HSA-1169091
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Mitotic Anaphase R-HSA-68882
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism R-HSA-1430728
Signaling by NOTCH R-HSA-157118
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI1 by the proteasome R-HSA-5610780
Degradation of DVL R-HSA-4641258
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog ligand biogenesis R-HSA-5358346
Developmental Biology R-HSA-1266738
p53-Independent DNA Damage Response R-HSA-69610
G2/M Transition R-HSA-69275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Post-translational protein modification R-HSA-597592
MAPK1/MAPK3 signaling R-HSA-5684996
Axon guidance R-HSA-422475
Regulation of mitotic cell cycle R-HSA-453276
Vpu mediated degradation of CD4 R-HSA-180534
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX1 R-HSA-8878171
Stabilization of p53 R-HSA-69541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cell Cycle Checkpoints R-HSA-69620
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to hypoxia R-HSA-1234174
G1/S Transition R-HSA-69206
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Immune System R-HSA-168256
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism of RNA R-HSA-8953854
Hh mutants abrogate ligand secretion R-HSA-5387390
Nervous system development R-HSA-9675108
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK family signaling cascades R-HSA-5683057
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
PTEN Regulation R-HSA-6807070
Innate Immune System R-HSA-168249
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of proteins R-HSA-392499
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of Apoptosis R-HSA-169911
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G1/S DNA Damage Checkpoints R-HSA-69615
C-type lectin receptors (CLRs) R-HSA-5621481
DNA Replication Pre-Initiation R-HSA-69002
Cyclin E associated events during G1/S transition R-HSA-69202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
Disease R-HSA-1643685
Hedgehog 'off' state R-HSA-5610787
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cytokine Signaling in Immune system R-HSA-1280215
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
HIV Infection R-HSA-162906
DNA Replication R-HSA-69306
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by ROBO receptors R-HSA-376176
Apoptosis R-HSA-109581
Ub-specific processing proteases R-HSA-5689880
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of RNA R-HSA-8953854
Hedgehog 'on' state R-HSA-5632684
M Phase R-HSA-68886
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic Anaphase R-HSA-68882
Cellular response to chemical stress R-HSA-9711123
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Transition R-HSA-69275
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by NOTCH R-HSA-157118
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G2-G2/M phases R-HSA-453274
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing-Cross presentation R-HSA-1236975
Downstream TCR signaling R-HSA-202424
RAF/MAP kinase cascade R-HSA-5673001
Programmed Cell Death R-HSA-5357801
Stabilization of p53 R-HSA-69541
Cell Cycle Checkpoints R-HSA-69620
Gene expression (Transcription) R-HSA-74160
Separation of Sister Chromatids R-HSA-2467813
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ER-Phagosome pathway R-HSA-1236974
Asymmetric localization of PCP proteins R-HSA-4608870
Axon guidance R-HSA-422475
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX3 R-HSA-8878159
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle, Mitotic R-HSA-69278
Regulation of mitotic cell cycle R-HSA-453276
UCH proteinases R-HSA-5689603
TCR signaling R-HSA-202403
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
ABC-family proteins mediated transport R-HSA-382556
Signaling by Hedgehog R-HSA-5358351
Transport of small molecules R-HSA-382551
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX2 R-HSA-8878166
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Degradation of AXIN R-HSA-4641257
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Neutrophil degranulation R-HSA-6798695
Infectious disease R-HSA-5663205
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Independent DNA Damage Response R-HSA-69610
Orc1 removal from chromatin R-HSA-68949
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of RAS by GAPs R-HSA-5658442
Signal Transduction R-HSA-162582
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'off' state R-HSA-5610787
MAPK1/MAPK3 signaling R-HSA-5684996
Generic Transcription Pathway R-HSA-212436
ABC transporter disorders R-HSA-5619084
Post-translational protein modification R-HSA-597592
Regulation of PTEN stability and activity R-HSA-8948751
MAPK family signaling cascades R-HSA-5683057
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of Apoptosis R-HSA-169911
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of polyamines R-HSA-351202
Signaling by Interleukins R-HSA-449147
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vif-mediated degradation of APOBEC3G R-HSA-180585
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI2 by the proteasome R-HSA-5610783
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH4 R-HSA-9013694
Innate Immune System R-HSA-168249
G1/S Transition R-HSA-69206
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants abrogate ligand secretion R-HSA-5387390
Nervous system development R-HSA-9675108
Degradation of DVL R-HSA-4641258
PTEN Regulation R-HSA-6807070
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
FCERI mediated NF-kB activation R-HSA-2871837
Cellular responses to stress R-HSA-2262752
Hedgehog ligand biogenesis R-HSA-5358346
CLEC7A (Dectin-1) signaling R-HSA-5607764
Immune System R-HSA-168256
Regulation of RUNX2 expression and activity R-HSA-8939902
Developmental Biology R-HSA-1266738
Deubiquitination R-HSA-5688426
Interleukin-1 signaling R-HSA-9020702
Synthesis of DNA R-HSA-69239
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
p53-Dependent G1 DNA Damage Response R-HSA-69563
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Assembly of the pre-replicative complex R-HSA-68867
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of Apoptosis R-HSA-169911
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Intracellular signaling by second messengers R-HSA-9006925
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of AXIN R-HSA-4641257
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of proteins R-HSA-392499
ABC-family proteins mediated transport R-HSA-382556
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
Generic Transcription Pathway R-HSA-212436
Cyclin E associated events during G1/S transition R-HSA-69202
HIV Infection R-HSA-162906
Cellular response to hypoxia R-HSA-1234174
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX2 R-HSA-8878166
Disorders of transmembrane transporters R-HSA-5619115
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Post-translational protein modification R-HSA-597592
Degradation of DVL R-HSA-4641258
Separation of Sister Chromatids R-HSA-2467813
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G1/S DNA Damage Checkpoints R-HSA-69615
UCH proteinases R-HSA-5689603
Mitotic Anaphase R-HSA-68882
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Neutrophil degranulation R-HSA-6798695
RNA Polymerase II Transcription R-HSA-73857
G1/S Transition R-HSA-69206
Regulation of RUNX2 expression and activity R-HSA-8939902
DNA Replication Pre-Initiation R-HSA-69002
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Nervous system development R-HSA-9675108
Transport of small molecules R-HSA-382551
Developmental Biology R-HSA-1266738
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
Orc1 removal from chromatin R-HSA-68949
Cell Cycle Checkpoints R-HSA-69620
S Phase R-HSA-69242
Hh mutants abrogate ligand secretion R-HSA-5387390
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX3 expression and activity R-HSA-8941858
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by ROBO receptors R-HSA-376176
Stabilization of p53 R-HSA-69541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
Degradation of beta-catenin by the destruction complex R-HSA-195253
M Phase R-HSA-68886
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream TCR signaling R-HSA-202424
Antigen processing-Cross presentation R-HSA-1236975
Hh mutants are degraded by ERAD R-HSA-5362768
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PIP3 activates AKT signaling R-HSA-1257604
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK1/MAPK3 signaling R-HSA-5684996
ABC transporter disorders R-HSA-5619084
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mitotic cell cycle R-HSA-453276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
CLEC7A (Dectin-1) signaling R-HSA-5607764
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
Transcriptional regulation by RUNX3 R-HSA-8878159
Hedgehog 'off' state R-HSA-5610787
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH4 R-HSA-9013694
Hedgehog 'on' state R-HSA-5632684
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
Neddylation R-HSA-8951664
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to chemical stress R-HSA-9711123
Metabolism of RNA R-HSA-8953854
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
Gene expression (Transcription) R-HSA-74160
Metabolism of polyamines R-HSA-351202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Hedgehog R-HSA-5358351
Cell Cycle, Mitotic R-HSA-69278
ER-Phagosome pathway R-HSA-1236974
Host Interactions of HIV factors R-HSA-162909
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RAS by GAPs R-HSA-5658442
Cytokine Signaling in Immune system R-HSA-1280215
Deubiquitination R-HSA-5688426
PTEN Regulation R-HSA-6807070
Signaling by NOTCH R-HSA-157118
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by Interleukins R-HSA-449147
Degradation of GLI1 by the proteasome R-HSA-5610780
TCR signaling R-HSA-202403
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Innate Immune System R-HSA-168249
Beta-catenin independent WNT signaling R-HSA-3858494
Interleukin-1 signaling R-HSA-9020702
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Ub-specific processing proteases R-HSA-5689880
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle R-HSA-1640170
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'on' state R-HSA-5632684
Metabolism of RNA R-HSA-8953854
G2/M Checkpoints R-HSA-69481
ABC transporter disorders R-HSA-5619084
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RUNX2 expression and activity R-HSA-8939902
Assembly of the pre-replicative complex R-HSA-68867
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MAPK1/MAPK3 signaling R-HSA-5684996
Deubiquitination R-HSA-5688426
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX3 R-HSA-8878159
Developmental Biology R-HSA-1266738
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic Anaphase R-HSA-68882
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Beta-catenin independent WNT signaling R-HSA-3858494
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of GLI2 by the proteasome R-HSA-5610783
Disorders of transmembrane transporters R-HSA-5619115
Neutrophil degranulation R-HSA-6798695
Cell Cycle Checkpoints R-HSA-69620
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Apoptosis R-HSA-109581
Asymmetric localization of PCP proteins R-HSA-4608870
Axon guidance R-HSA-422475
Orc1 removal from chromatin R-HSA-68949
Cell Cycle, Mitotic R-HSA-69278
Hh mutants abrogate ligand secretion R-HSA-5387390
Nuclear events mediated by NFE2L2 R-HSA-9759194
Immune System R-HSA-168256
Regulation of Apoptosis R-HSA-169911
Disease R-HSA-1643685
Cellular response to hypoxia R-HSA-1234174
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cytokine Signaling in Immune system R-HSA-1280215
TCR signaling R-HSA-202403
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ER-Phagosome pathway R-HSA-1236974
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
FCERI mediated NF-kB activation R-HSA-2871837
Generic Transcription Pathway R-HSA-212436
p53-Independent DNA Damage Response R-HSA-69610
Degradation of DVL R-HSA-4641258
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog 'off' state R-HSA-5610787
Signaling by ROBO receptors R-HSA-376176
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stress R-HSA-2262752
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S DNA Damage Checkpoints R-HSA-69615
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
HIV Infection R-HSA-162906
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Nervous system development R-HSA-9675108
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Switching of origins to a post-replicative state R-HSA-69052
Degradation of AXIN R-HSA-4641257
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mitotic cell cycle R-HSA-453276
Signaling by NOTCH R-HSA-157118
Stabilization of p53 R-HSA-69541
Ub-specific processing proteases R-HSA-5689880
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
C-type lectin receptors (CLRs) R-HSA-5621481
Downstream TCR signaling R-HSA-202424
Metabolism of polyamines R-HSA-351202
Cyclin E associated events during G1/S transition R-HSA-69202
RAF/MAP kinase cascade R-HSA-5673001
S Phase R-HSA-69242
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by WNT R-HSA-195721
Signaling by NOTCH4 R-HSA-9013694
Synthesis of DNA R-HSA-69239
Class I MHC mediated antigen processing & presentation R-HSA-983169
Post-translational protein modification R-HSA-597592
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog ligand biogenesis R-HSA-5358346
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hh mutants are degraded by ERAD R-HSA-5362768
Gene expression (Transcription) R-HSA-74160
Regulation of PTEN stability and activity R-HSA-8948751
M Phase R-HSA-68886
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
UCH proteinases R-HSA-5689603
Interleukin-1 family signaling R-HSA-446652
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular responses to stimuli R-HSA-8953897
Regulation of RAS by GAPs R-HSA-5658442
G1/S Transition R-HSA-69206
PCP/CE pathway R-HSA-4086400
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cell Cycle R-HSA-1640170
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G2/M Transition R-HSA-69275
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1 DNA Damage Response R-HSA-69563
Infectious disease R-HSA-5663205
Antigen processing-Cross presentation R-HSA-1236975
Signal Transduction R-HSA-162582
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transport of small molecules R-HSA-382551
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RUNX3 expression and activity R-HSA-8941858
G2/M Transition R-HSA-69275
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
Interleukin-1 signaling R-HSA-9020702
Regulation of RUNX2 expression and activity R-HSA-8939902
TCR signaling R-HSA-202403
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of GLI2 by the proteasome R-HSA-5610783
Infectious disease R-HSA-5663205
Signaling by ROBO receptors R-HSA-376176
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cytokine Signaling in Immune system R-HSA-1280215
Orc1 removal from chromatin R-HSA-68949
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PTEN Regulation R-HSA-6807070
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Developmental Biology R-HSA-1266738
G2/M Checkpoints R-HSA-69481
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
G1/S Transition R-HSA-69206
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog ligand biogenesis R-HSA-5358346
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Disease R-HSA-1643685
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH R-HSA-157118
UCH proteinases R-HSA-5689603
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing-Cross presentation R-HSA-1236975
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cell Cycle R-HSA-1640170
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
RAF/MAP kinase cascade R-HSA-5673001
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ABC-family proteins mediated transport R-HSA-382556
M Phase R-HSA-68886
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Generic Transcription Pathway R-HSA-212436
Synthesis of DNA R-HSA-69239
Cell Cycle, Mitotic R-HSA-69278
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signal Transduction R-HSA-162582
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of RNA R-HSA-8953854
PIP3 activates AKT signaling R-HSA-1257604
DNA Replication R-HSA-69306
Assembly of the pre-replicative complex R-HSA-68867
Regulation of Apoptosis R-HSA-169911
Disorders of transmembrane transporters R-HSA-5619115
Programmed Cell Death R-HSA-5357801
CLEC7A (Dectin-1) signaling R-HSA-5607764
Nuclear events mediated by NFE2L2 R-HSA-9759194
Stabilization of p53 R-HSA-69541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stimuli R-HSA-8953897
Cellular response to chemical stress R-HSA-9711123
Innate Immune System R-HSA-168249
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Downstream TCR signaling R-HSA-202424
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hedgehog 'off' state R-HSA-5610787
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Asymmetric localization of PCP proteins R-HSA-4608870
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Independent DNA Damage Response R-HSA-69610
Transcriptional regulation by RUNX3 R-HSA-8878159
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HIV Infection R-HSA-162906
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Class I MHC mediated antigen processing & presentation R-HSA-983169
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Neutrophil degranulation R-HSA-6798695
Mitotic G1 phase and G1/S transition R-HSA-453279
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH4 R-HSA-9013694
Signaling by WNT R-HSA-195721
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular response to hypoxia R-HSA-1234174
MAPK1/MAPK3 signaling R-HSA-5684996
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle Checkpoints R-HSA-69620
ER-Phagosome pathway R-HSA-1236974
Transport of small molecules R-HSA-382551
Degradation of AXIN R-HSA-4641257
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Mitotic Anaphase R-HSA-68882
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of polyamines R-HSA-351202
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX2 R-HSA-8878166
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
C-type lectin receptors (CLRs) R-HSA-5621481
Beta-catenin independent WNT signaling R-HSA-3858494
Neddylation R-HSA-8951664
MAPK family signaling cascades R-HSA-5683057
Post-translational protein modification R-HSA-597592
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
S Phase R-HSA-69242
Regulation of PTEN stability and activity R-HSA-8948751
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Defective CFTR causes cystic fibrosis R-HSA-5678895
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RAS by GAPs R-HSA-5658442
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
ABC transporter disorders R-HSA-5619084
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
UCH proteinases R-HSA-5689603
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of PTEN stability and activity R-HSA-8948751
MAPK1/MAPK3 signaling R-HSA-5684996
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
HIV Infection R-HSA-162906
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle, Mitotic R-HSA-69278
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of AXIN R-HSA-4641257
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication Pre-Initiation R-HSA-69002
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Beta-catenin independent WNT signaling R-HSA-3858494
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Apoptosis R-HSA-109581
Signaling by ROBO receptors R-HSA-376176
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Nervous system development R-HSA-9675108
Mitotic G2-G2/M phases R-HSA-453274
TCR signaling R-HSA-202403
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'on' state R-HSA-5632684
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH R-HSA-157118
Hedgehog ligand biogenesis R-HSA-5358346
Transport of small molecules R-HSA-382551
Cyclin E associated events during G1/S transition R-HSA-69202
Metabolism of amino acids and derivatives R-HSA-71291
M Phase R-HSA-68886
Cellular responses to stress R-HSA-2262752
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Orc1 removal from chromatin R-HSA-68949
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX3 R-HSA-8878159
Class I MHC mediated antigen processing & presentation R-HSA-983169
Deubiquitination R-HSA-5688426
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
Separation of Sister Chromatids R-HSA-2467813
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Checkpoints R-HSA-69481
ER-Phagosome pathway R-HSA-1236974
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Neddylation R-HSA-8951664
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Post-translational protein modification R-HSA-597592
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of DVL R-HSA-4641258
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PTEN Regulation R-HSA-6807070
FCERI mediated NF-kB activation R-HSA-2871837
Defective CFTR causes cystic fibrosis R-HSA-5678895
Programmed Cell Death R-HSA-5357801
PCP/CE pathway R-HSA-4086400
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by WNT R-HSA-195721
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PIP3 activates AKT signaling R-HSA-1257604
G2/M Transition R-HSA-69275
Infectious disease R-HSA-5663205
C-type lectin receptors (CLRs) R-HSA-5621481
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Innate Immune System R-HSA-168249
Regulation of mitotic cell cycle R-HSA-453276
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cell Cycle Checkpoints R-HSA-69620
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Hedgehog R-HSA-5358351
Host Interactions of HIV factors R-HSA-162909
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of polyamines R-HSA-351202
Metabolism of RNA R-HSA-8953854
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Stabilization of p53 R-HSA-69541
Interleukin-1 signaling R-HSA-9020702
Asymmetric localization of PCP proteins R-HSA-4608870
Generic Transcription Pathway R-HSA-212436
G1/S Transition R-HSA-69206
Signal Transduction R-HSA-162582
DNA Replication R-HSA-69306
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
S Phase R-HSA-69242
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of proteins R-HSA-392499
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by NOTCH4 R-HSA-9013694
Switching of origins to a post-replicative state R-HSA-69052
Metabolism R-HSA-1430728
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transcriptional regulation by RUNX2 R-HSA-8878166
Hedgehog 'off' state R-HSA-5610787
Signaling by Interleukins R-HSA-449147
Vpu mediated degradation of CD4 R-HSA-180534
Developmental Biology R-HSA-1266738
CLEC7A (Dectin-1) signaling R-HSA-5607764
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Dependent G1 DNA Damage Response R-HSA-69563
Disease R-HSA-1643685
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Ub-specific processing proteases R-HSA-5689880
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing-Cross presentation R-HSA-1236975
Degradation of GLI1 by the proteasome R-HSA-5610780
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Synthesis of DNA R-HSA-69239
Adaptive Immune System R-HSA-1280218
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of DVL R-HSA-4641258
Antigen processing-Cross presentation R-HSA-1236975
Mitotic Metaphase and Anaphase R-HSA-2555396
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic G1 phase and G1/S transition R-HSA-453279
Separation of Sister Chromatids R-HSA-2467813
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic Anaphase R-HSA-68882
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Generic Transcription Pathway R-HSA-212436
Regulation of mitotic cell cycle R-HSA-453276
Infectious disease R-HSA-5663205
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of AXIN R-HSA-4641257
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX2 R-HSA-8878166
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stimuli R-HSA-8953897
Transport of small molecules R-HSA-382551
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transcriptional regulation by RUNX3 R-HSA-8878159
C-type lectin receptors (CLRs) R-HSA-5621481
Synthesis of DNA R-HSA-69239
Stabilization of p53 R-HSA-69541
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1 DNA Damage Response R-HSA-69563
Programmed Cell Death R-HSA-5357801
Cell Cycle, Mitotic R-HSA-69278
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Deubiquitination R-HSA-5688426
Cellular responses to stress R-HSA-2262752
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
Metabolism of polyamines R-HSA-351202
Cyclin E associated events during G1/S transition R-HSA-69202
Intracellular signaling by second messengers R-HSA-9006925
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
Downstream TCR signaling R-HSA-202424
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of RUNX2 expression and activity R-HSA-8939902
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCR signaling R-HSA-202403
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle R-HSA-1640170
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH4 R-HSA-9013694
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'on' state R-HSA-5632684
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vpu mediated degradation of CD4 R-HSA-180534
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to chemical stress R-HSA-9711123
KEAP1-NFE2L2 pathway R-HSA-9755511
Innate Immune System R-HSA-168249
Beta-catenin independent WNT signaling R-HSA-3858494
p53-Independent DNA Damage Response R-HSA-69610
Immune System R-HSA-168256
ABC transporter disorders R-HSA-5619084
Metabolism R-HSA-1430728
Degradation of GLI2 by the proteasome R-HSA-5610783
MAPK6/MAPK4 signaling R-HSA-5687128
Orc1 removal from chromatin R-HSA-68949
Gene expression (Transcription) R-HSA-74160
Neddylation R-HSA-8951664
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Post-translational protein modification R-HSA-597592
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Neutrophil degranulation R-HSA-6798695
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
MAPK family signaling cascades R-HSA-5683057
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G1/S Transition R-HSA-69206
Hh mutants abrogate ligand secretion R-HSA-5387390
DNA Replication R-HSA-69306
RAF/MAP kinase cascade R-HSA-5673001
Cytokine Signaling in Immune system R-HSA-1280215
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of proteins R-HSA-392499
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RAS by GAPs R-HSA-5658442
Hh mutants are degraded by ERAD R-HSA-5362768
Hedgehog ligand biogenesis R-HSA-5358346
PCP/CE pathway R-HSA-4086400
ABC-family proteins mediated transport R-HSA-382556
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to hypoxia R-HSA-1234174
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
Interleukin-1 signaling R-HSA-9020702
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle Checkpoints R-HSA-69620
S Phase R-HSA-69242
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by Interleukins R-HSA-449147
Switching of origins to a post-replicative state R-HSA-69052
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
HIV Infection R-HSA-162906
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ub-specific processing proteases R-HSA-5689880
DNA Replication Pre-Initiation R-HSA-69002
Nuclear events mediated by NFE2L2 R-HSA-9759194
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721

Expression Atlas ENSG00000165916
NCBI gene (formerly Entrezgene) 5702
GeneCards 9549
HGNC Symbol HGNC:9549
MIM gene 186852
MIM morbid 619354
UniProtKB Gene Name R4GNH3
WikiGene 5702