Gene: ATP1A2
Ensembl ID : ENSG00000018625
Description: ATPase Na+/K+ transporting subunit alpha 2
Gene Synonyms: FHM2,MHP2
6 APIs:
207 Possible Orthologues:

Potential therapeutics for SARS R-HSA-9679191
Transport of small molecules R-HSA-382551
Ion channel transport R-HSA-983712
Cardiac conduction R-HSA-5576891
SARS-CoV Infections R-HSA-9679506
Ion transport by P-type ATPases R-HSA-936837
Infectious disease R-HSA-5663205
Muscle contraction R-HSA-397014
Disease R-HSA-1643685
Ion homeostasis R-HSA-5578775
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV Infections R-HSA-9679506
Ion channel transport R-HSA-983712
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
Ion transport by P-type ATPases R-HSA-936837
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Infectious disease R-HSA-5663205
Ion homeostasis R-HSA-5578775
Cardiac conduction R-HSA-5576891
Transport of small molecules R-HSA-382551
Ion channel transport R-HSA-983712
Ion transport by P-type ATPases R-HSA-936837
Cardiac conduction R-HSA-5576891
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV Infections R-HSA-9679506
Muscle contraction R-HSA-397014
Ion homeostasis R-HSA-5578775
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Muscle contraction R-HSA-397014
SARS-CoV Infections R-HSA-9679506
Ion transport by P-type ATPases R-HSA-936837
Cardiac conduction R-HSA-5576891
Ion homeostasis R-HSA-5578775
Potential therapeutics for SARS R-HSA-9679191
Ion channel transport R-HSA-983712
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Potential therapeutics for SARS R-HSA-9679191
Transport of small molecules R-HSA-382551
Ion homeostasis R-HSA-5578775
SARS-CoV Infections R-HSA-9679506
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Infectious disease R-HSA-5663205
Ion channel transport R-HSA-983712
Disease R-HSA-1643685
Ion transport by P-type ATPases R-HSA-936837
Muscle contraction R-HSA-397014
Disease R-HSA-1643685
Ion channel transport R-HSA-983712
Ion transport by P-type ATPases R-HSA-936837
Cardiac conduction R-HSA-5576891
SARS-CoV Infections R-HSA-9679506
Ion homeostasis R-HSA-5578775
Transport of small molecules R-HSA-382551
Infectious disease R-HSA-5663205
Ion homeostasis R-HSA-5578775
Transport of small molecules R-HSA-382551
Potential therapeutics for SARS R-HSA-9679191
Ion transport by P-type ATPases R-HSA-936837
Infectious disease R-HSA-5663205
Cardiac conduction R-HSA-5576891
Ion channel transport R-HSA-983712
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
Muscle contraction R-HSA-397014
Ion transport by P-type ATPases R-HSA-936837
Infectious disease R-HSA-5663205
Cardiac conduction R-HSA-5576891
Transport of small molecules R-HSA-382551
Ion homeostasis R-HSA-5578775
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
Ion channel transport R-HSA-983712
Disease R-HSA-1643685
SARS-CoV Infections R-HSA-9679506
Muscle contraction R-HSA-397014
Ion transport by P-type ATPases R-HSA-936837
Ion channel transport R-HSA-983712
Ion homeostasis R-HSA-5578775
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
Cardiac conduction R-HSA-5576891
Infectious disease R-HSA-5663205
Transport of small molecules R-HSA-382551
Potential therapeutics for SARS R-HSA-9679191
Ion channel transport R-HSA-983712
Infectious disease R-HSA-5663205
Ion transport by P-type ATPases R-HSA-936837
Muscle contraction R-HSA-397014
SARS-CoV Infections R-HSA-9679506
Cardiac conduction R-HSA-5576891
Potential therapeutics for SARS R-HSA-9679191
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Ion homeostasis R-HSA-5578775

Expression Atlas ENSG00000018625
LRG display in Ensembl gene LRG_6
NCBI gene (formerly Entrezgene) 477
GeneCards 800
HGNC Symbol HGNC:800
MIM gene 182340
MIM morbid 619605
UniProtKB Gene Name P50993
WikiGene 477
Gene: PSMC5
Ensembl ID : ENSG00000087191
Description: proteasome 26S subunit, ATPase 5
Gene Synonyms: P45,P45/SUG,RPT6,S8,SUG-1,SUG1,TBP10,TRIP1
5 APIs:
219 Possible Orthologues:

G1/S Transition R-HSA-69206
G2/M Checkpoints R-HSA-69481
Hedgehog 'on' state R-HSA-5632684
S Phase R-HSA-69242
Degradation of DVL R-HSA-4641258
Signaling by NOTCH R-HSA-157118
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TCR signaling R-HSA-202403
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK family signaling cascades R-HSA-5683057
UCH proteinases R-HSA-5689603
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Deubiquitination R-HSA-5688426
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of amino acids and derivatives R-HSA-71291
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular responses to stimuli R-HSA-8953897
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
ABC-family proteins mediated transport R-HSA-382556
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle, Mitotic R-HSA-69278
Cytokine Signaling in Immune system R-HSA-1280215
Generic Transcription Pathway R-HSA-212436
Degradation of DVL R-HSA-4641258
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of Apoptosis R-HSA-169911
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK6/MAPK4 signaling R-HSA-5687128
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH4 R-HSA-9013694
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
Cell Cycle R-HSA-1640170
Programmed Cell Death R-HSA-5357801
Regulation of RAS by GAPs R-HSA-5658442
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog 'on' state R-HSA-5632684
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by ROBO receptors R-HSA-376176
Mitotic Anaphase R-HSA-68882
Regulation of RUNX3 expression and activity R-HSA-8941858
Negative regulation of NOTCH4 signaling R-HSA-9604323
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX2 expression and activity R-HSA-8939902
Beta-catenin independent WNT signaling R-HSA-3858494
Apoptosis R-HSA-109581
p53-Independent DNA Damage Response R-HSA-69610
Degradation of beta-catenin by the destruction complex R-HSA-195253
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
Cyclin E associated events during G1/S transition R-HSA-69202
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 signaling R-HSA-9020702
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by the B Cell Receptor (BCR) R-HSA-983705
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular response to chemical stress R-HSA-9711123
Orc1 removal from chromatin R-HSA-68949
Metabolism of RNA R-HSA-8953854
Transcriptional regulation by RUNX2 R-HSA-8878166
PIP3 activates AKT signaling R-HSA-1257604
Hh mutants are degraded by ERAD R-HSA-5362768
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ABC transporter disorders R-HSA-5619084
ER-Phagosome pathway R-HSA-1236974
MAPK1/MAPK3 signaling R-HSA-5684996
Host Interactions of HIV factors R-HSA-162909
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX1 R-HSA-8878171
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stress R-HSA-2262752
HIV Infection R-HSA-162906
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by NOTCH R-HSA-157118
Stabilization of p53 R-HSA-69541
Immune System R-HSA-168256
Metabolism of proteins R-HSA-392499
Developmental Biology R-HSA-1266738
Innate Immune System R-HSA-168249
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants abrogate ligand secretion R-HSA-5387390
S Phase R-HSA-69242
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle Checkpoints R-HSA-69620
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
PTEN Regulation R-HSA-6807070
Switching of origins to a post-replicative state R-HSA-69052
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Asymmetric localization of PCP proteins R-HSA-4608870
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication Pre-Initiation R-HSA-69002
Infectious disease R-HSA-5663205
PCP/CE pathway R-HSA-4086400
FCERI mediated NF-kB activation R-HSA-2871837
Activation of NF-kappaB in B cells R-HSA-1169091
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mitotic cell cycle R-HSA-453276
Signaling by WNT R-HSA-195721
Metabolism of polyamines R-HSA-351202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ub-specific processing proteases R-HSA-5689880
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by Interleukins R-HSA-449147
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Mitotic G2-G2/M phases R-HSA-453274
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog 'off' state R-HSA-5610787
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
Class I MHC mediated antigen processing & presentation R-HSA-983169
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Deubiquitination R-HSA-5688426
Programmed Cell Death R-HSA-5357801
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nuclear events mediated by NFE2L2 R-HSA-9759194
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Signaling by Interleukins R-HSA-449147
HIV Infection R-HSA-162906
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism R-HSA-1430728
Ub-specific processing proteases R-HSA-5689880
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'off' state R-HSA-5610787
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle R-HSA-1640170
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
Transport of small molecules R-HSA-382551
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin E associated events during G1/S transition R-HSA-69202
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream TCR signaling R-HSA-202424
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
TCR signaling R-HSA-202403
Synthesis of DNA R-HSA-69239
Signaling by NOTCH R-HSA-157118
Cellular responses to stress R-HSA-2262752
FCERI mediated NF-kB activation R-HSA-2871837
Beta-catenin independent WNT signaling R-HSA-3858494
Neddylation R-HSA-8951664
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Gene expression (Transcription) R-HSA-74160
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Post-translational protein modification R-HSA-597592
p53-Dependent G1 DNA Damage Response R-HSA-69563
PCP/CE pathway R-HSA-4086400
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
DNA Replication R-HSA-69306
G2/M Transition R-HSA-69275
Stabilization of p53 R-HSA-69541
Signaling by WNT R-HSA-195721
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing-Cross presentation R-HSA-1236975
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of AXIN R-HSA-4641257
Disorders of transmembrane transporters R-HSA-5619115
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
G2/M Checkpoints R-HSA-69481
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mitotic cell cycle R-HSA-453276
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of RNA R-HSA-8953854
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular response to hypoxia R-HSA-1234174
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'on' state R-HSA-5632684
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
ABC-family proteins mediated transport R-HSA-382556
Regulation of RAS by GAPs R-HSA-5658442
Immune System R-HSA-168256
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stimuli R-HSA-8953897
ER-Phagosome pathway R-HSA-1236974
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Class I MHC mediated antigen processing & presentation R-HSA-983169
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Mitotic Anaphase R-HSA-68882
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 family signaling R-HSA-446652
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Adaptive Immune System R-HSA-1280218
Vif-mediated degradation of APOBEC3G R-HSA-180585
Apoptosis R-HSA-109581
G1/S Transition R-HSA-69206
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by ROBO receptors R-HSA-376176
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of Apoptosis R-HSA-169911
Regulation of RUNX3 expression and activity R-HSA-8941858
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 signaling R-HSA-9020702
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of PTEN stability and activity R-HSA-8948751
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Generic Transcription Pathway R-HSA-212436
S Phase R-HSA-69242
Axon guidance R-HSA-422475
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Mitotic G2-G2/M phases R-HSA-453274
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic G1 phase and G1/S transition R-HSA-453279
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PIP3 activates AKT signaling R-HSA-1257604
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of DVL R-HSA-4641258
Nervous system development R-HSA-9675108
p53-Independent DNA Damage Response R-HSA-69610
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ABC-family proteins mediated transport R-HSA-382556
Infectious disease R-HSA-5663205
Metabolism R-HSA-1430728
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of RUNX3 expression and activity R-HSA-8941858
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Mitotic Metaphase and Anaphase R-HSA-2555396
ABC transporter disorders R-HSA-5619084
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Innate Immune System R-HSA-168249
G2/M Checkpoints R-HSA-69481
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RAS by GAPs R-HSA-5658442
RAF/MAP kinase cascade R-HSA-5673001
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by WNT R-HSA-195721
Stabilization of p53 R-HSA-69541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Activation of NF-kappaB in B cells R-HSA-1169091
Axon guidance R-HSA-422475
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hedgehog ligand biogenesis R-HSA-5358346
Cytokine Signaling in Immune system R-HSA-1280215
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX2 R-HSA-8878166
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RNA Polymerase II Transcription R-HSA-73857
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
CLEC7A (Dectin-1) signaling R-HSA-5607764
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream TCR signaling R-HSA-202424
Immune System R-HSA-168256
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MAPK family signaling cascades R-HSA-5683057
Nervous system development R-HSA-9675108
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Disorders of transmembrane transporters R-HSA-5619115
Regulation of mitotic cell cycle R-HSA-453276
Developmental Biology R-HSA-1266738
Hedgehog 'off' state R-HSA-5610787
Adaptive Immune System R-HSA-1280218
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PCP/CE pathway R-HSA-4086400
Assembly of the pre-replicative complex R-HSA-68867
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog 'on' state R-HSA-5632684
UCH proteinases R-HSA-5689603
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Independent DNA Damage Response R-HSA-69610
TCR signaling R-HSA-202403
Regulation of expression of SLITs and ROBOs R-HSA-9010553
C-type lectin receptors (CLRs) R-HSA-5621481
Generic Transcription Pathway R-HSA-212436
Deubiquitination R-HSA-5688426
Cellular responses to stress R-HSA-2262752
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX3 R-HSA-8878159
HIV Infection R-HSA-162906
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of polyamines R-HSA-351202
Cell Cycle Checkpoints R-HSA-69620
Defective CFTR causes cystic fibrosis R-HSA-5678895
Neddylation R-HSA-8951664
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of RNA R-HSA-8953854
Signaling by Hedgehog R-HSA-5358351
Separation of Sister Chromatids R-HSA-2467813
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S Transition R-HSA-69206
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Synthesis of DNA R-HSA-69239
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G2-G2/M phases R-HSA-453274
PTEN Regulation R-HSA-6807070
Regulation of Apoptosis R-HSA-169911
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of proteins R-HSA-392499
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication R-HSA-69306
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI2 by the proteasome R-HSA-5610783
Vif-mediated degradation of APOBEC3G R-HSA-180585
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stimuli R-HSA-8953897
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
Mitotic G1 phase and G1/S transition R-HSA-453279
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of amino acids and derivatives R-HSA-71291
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
S Phase R-HSA-69242
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Antigen processing-Cross presentation R-HSA-1236975
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI1 by the proteasome R-HSA-5610780
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to hypoxia R-HSA-1234174
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle, Mitotic R-HSA-69278
PIP3 activates AKT signaling R-HSA-1257604
Host Interactions of HIV factors R-HSA-162909
FCERI mediated NF-kB activation R-HSA-2871837
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX3 R-HSA-8878159
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of polyamines R-HSA-351202
Assembly of the pre-replicative complex R-HSA-68867
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
ER-Phagosome pathway R-HSA-1236974
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
Neddylation R-HSA-8951664
Degradation of AXIN R-HSA-4641257
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hedgehog 'on' state R-HSA-5632684
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
Synthesis of DNA R-HSA-69239
Degradation of DVL R-HSA-4641258
Hh mutants abrogate ligand secretion R-HSA-5387390
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
Signaling by NOTCH R-HSA-157118
Mitotic G2-G2/M phases R-HSA-453274
Metabolism R-HSA-1430728
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
Cell Cycle R-HSA-1640170
RAF/MAP kinase cascade R-HSA-5673001
Cellular response to hypoxia R-HSA-1234174
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by NOTCH4 R-HSA-9013694
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signal Transduction R-HSA-162582
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mitotic cell cycle R-HSA-453276
ABC transporter disorders R-HSA-5619084
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCR signaling R-HSA-202403
Regulation of Apoptosis R-HSA-169911
S Phase R-HSA-69242
Signaling by Interleukins R-HSA-449147
DNA Replication R-HSA-69306
Class I MHC mediated antigen processing & presentation R-HSA-983169
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
Cyclin E associated events during G1/S transition R-HSA-69202
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disease R-HSA-1643685
Signaling by Hedgehog R-HSA-5358351
Mitotic Metaphase and Anaphase R-HSA-2555396
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
HIV Infection R-HSA-162906
Degradation of GLI1 by the proteasome R-HSA-5610780
Programmed Cell Death R-HSA-5357801
Metabolism of RNA R-HSA-8953854
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transcriptional regulation by RUNX1 R-HSA-8878171
Post-translational protein modification R-HSA-597592
Regulation of RAS by GAPs R-HSA-5658442
Deubiquitination R-HSA-5688426
Adaptive Immune System R-HSA-1280218
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ub-specific processing proteases R-HSA-5689880
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
Signaling by ROBO receptors R-HSA-376176
Cell Cycle, Mitotic R-HSA-69278
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
M Phase R-HSA-68886
Hh mutants are degraded by ERAD R-HSA-5362768
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stimuli R-HSA-8953897
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by WNT R-HSA-195721
PCP/CE pathway R-HSA-4086400
PIP3 activates AKT signaling R-HSA-1257604
Cellular response to chemical stress R-HSA-9711123
Vpu mediated degradation of CD4 R-HSA-180534
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of PTEN stability and activity R-HSA-8948751
Stabilization of p53 R-HSA-69541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Transition R-HSA-69275
Regulation of expression of SLITs and ROBOs R-HSA-9010553
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of amino acids and derivatives R-HSA-71291
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Anaphase R-HSA-68882
Downstream TCR signaling R-HSA-202424
Host Interactions of HIV factors R-HSA-162909
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'off' state R-HSA-5610787
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing-Cross presentation R-HSA-1236975
FCERI mediated NF-kB activation R-HSA-2871837
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
KEAP1-NFE2L2 pathway R-HSA-9755511
Cytokine Signaling in Immune system R-HSA-1280215
Hedgehog ligand biogenesis R-HSA-5358346
C-type lectin receptors (CLRs) R-HSA-5621481
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Transport of small molecules R-HSA-382551
G1/S Transition R-HSA-69206
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX2 R-HSA-8878166
Interleukin-1 signaling R-HSA-9020702
Innate Immune System R-HSA-168249
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
PCP/CE pathway R-HSA-4086400
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
Mitotic G1 phase and G1/S transition R-HSA-453279
TCR signaling R-HSA-202403
p53-Dependent G1 DNA Damage Response R-HSA-69563
Axon guidance R-HSA-422475
ABC transporter disorders R-HSA-5619084
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Generic Transcription Pathway R-HSA-212436
Cell Cycle Checkpoints R-HSA-69620
PTEN Regulation R-HSA-6807070
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent DNA Damage Response R-HSA-69610
Asymmetric localization of PCP proteins R-HSA-4608870
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Stabilization of p53 R-HSA-69541
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'on' state R-HSA-5632684
Immune System R-HSA-168256
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of PTEN stability and activity R-HSA-8948751
RAF/MAP kinase cascade R-HSA-5673001
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of AXIN R-HSA-4641257
Metabolism of amino acids and derivatives R-HSA-71291
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vpu mediated degradation of CD4 R-HSA-180534
G1/S DNA Damage Checkpoints R-HSA-69615
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH R-HSA-157118
Signaling by the B Cell Receptor (BCR) R-HSA-983705
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mitotic cell cycle R-HSA-453276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Class I MHC mediated antigen processing & presentation R-HSA-983169
Programmed Cell Death R-HSA-5357801
Separation of Sister Chromatids R-HSA-2467813
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Nuclear events mediated by NFE2L2 R-HSA-9759194
Interleukin-1 signaling R-HSA-9020702
G2/M Checkpoints R-HSA-69481
Metabolism of proteins R-HSA-392499
Orc1 removal from chromatin R-HSA-68949
Defective CFTR causes cystic fibrosis R-HSA-5678895
HIV Infection R-HSA-162906
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Cyclin E associated events during G1/S transition R-HSA-69202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of Apoptosis R-HSA-169911
Adaptive Immune System R-HSA-1280218
Disorders of transmembrane transporters R-HSA-5619115
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by ROBO receptors R-HSA-376176
Metabolism of polyamines R-HSA-351202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Synthesis of DNA R-HSA-69239
Switching of origins to a post-replicative state R-HSA-69052
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
KEAP1-NFE2L2 pathway R-HSA-9755511
Ub-specific processing proteases R-HSA-5689880
Signaling by Interleukins R-HSA-449147
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Hedgehog ligand biogenesis R-HSA-5358346
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH4 R-HSA-9013694
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX3 R-HSA-8878159
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of RUNX3 expression and activity R-HSA-8941858
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing-Cross presentation R-HSA-1236975
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic G2-G2/M phases R-HSA-453274
ER-Phagosome pathway R-HSA-1236974
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Host Interactions of HIV factors R-HSA-162909
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
Cell Cycle R-HSA-1640170
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Cytokine Signaling in Immune system R-HSA-1280215
Vif-mediated degradation of APOBEC3G R-HSA-180585
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of RNA R-HSA-8953854
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S Transition R-HSA-69206
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
Interleukin-1 family signaling R-HSA-446652
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Anaphase R-HSA-68882
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX1 R-HSA-8878171
G2/M Checkpoints R-HSA-69481
Downstream TCR signaling R-HSA-202424
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants are degraded by ERAD R-HSA-5362768
Orc1 removal from chromatin R-HSA-68949
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Generic Transcription Pathway R-HSA-212436
S Phase R-HSA-69242
Ub-specific processing proteases R-HSA-5689880
Negative regulation of NOTCH4 signaling R-HSA-9604323
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FCERI mediated NF-kB activation R-HSA-2871837
Nuclear events mediated by NFE2L2 R-HSA-9759194
PCP/CE pathway R-HSA-4086400
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
UCH proteinases R-HSA-5689603
Cellular responses to stimuli R-HSA-8953897
Neddylation R-HSA-8951664
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Vpu mediated degradation of CD4 R-HSA-180534
Antigen processing-Cross presentation R-HSA-1236975
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of AXIN R-HSA-4641257
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RAS by GAPs R-HSA-5658442
Immune System R-HSA-168256
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signal Transduction R-HSA-162582
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of DVL R-HSA-4641258
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Intracellular signaling by second messengers R-HSA-9006925
HIV Infection R-HSA-162906
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
Disease R-HSA-1643685
Signaling by Interleukins R-HSA-449147
Metabolism of RNA R-HSA-8953854
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Synthesis of DNA R-HSA-69239
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Metaphase and Anaphase R-HSA-2555396
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCF dependent signaling in response to WNT R-HSA-201681
C-type lectin receptors (CLRs) R-HSA-5621481
ABC transporter disorders R-HSA-5619084
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH R-HSA-157118
Cyclin E associated events during G1/S transition R-HSA-69202
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Separation of Sister Chromatids R-HSA-2467813
Metabolism R-HSA-1430728
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by ROBO receptors R-HSA-376176
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Interleukin-1 signaling R-HSA-9020702
Mitotic Anaphase R-HSA-68882
ABC-family proteins mediated transport R-HSA-382556
Programmed Cell Death R-HSA-5357801
MAPK family signaling cascades R-HSA-5683057
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to chemical stress R-HSA-9711123
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by NOTCH4 R-HSA-9013694
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent DNA Damage Response R-HSA-69610
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stress R-HSA-2262752
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transport of small molecules R-HSA-382551
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Hedgehog R-HSA-5358351
Metabolism of amino acids and derivatives R-HSA-71291
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic G2-G2/M phases R-HSA-453274
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
Developmental Biology R-HSA-1266738
Regulation of RUNX2 expression and activity R-HSA-8939902
Adaptive Immune System R-HSA-1280218
Post-translational protein modification R-HSA-597592
Apoptosis R-HSA-109581
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog ligand biogenesis R-HSA-5358346
Gene expression (Transcription) R-HSA-74160
TCR signaling R-HSA-202403
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of NF-kappaB in B cells R-HSA-1169091
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 family signaling R-HSA-446652
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
HIV Infection R-HSA-162906
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of polyamines R-HSA-351202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Class I MHC mediated antigen processing & presentation R-HSA-983169
ABC-family proteins mediated transport R-HSA-382556
Metabolism R-HSA-1430728
PCP/CE pathway R-HSA-4086400
FCERI mediated NF-kB activation R-HSA-2871837
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Gene expression (Transcription) R-HSA-74160
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK6/MAPK4 signaling R-HSA-5687128
G2/M Transition R-HSA-69275
Transport of small molecules R-HSA-382551
Cell Cycle Checkpoints R-HSA-69620
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Ub-specific processing proteases R-HSA-5689880
Degradation of AXIN R-HSA-4641257
Developmental Biology R-HSA-1266738
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic G2-G2/M phases R-HSA-453274
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'on' state R-HSA-5632684
Degradation of DVL R-HSA-4641258
Cell Cycle R-HSA-1640170
Cellular responses to stimuli R-HSA-8953897
Post-translational protein modification R-HSA-597592
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
UCH proteinases R-HSA-5689603
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
Interleukin-1 signaling R-HSA-9020702
Signaling by Interleukins R-HSA-449147
Negative regulation of NOTCH4 signaling R-HSA-9604323
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
KEAP1-NFE2L2 pathway R-HSA-9755511
Neddylation R-HSA-8951664
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disorders of transmembrane transporters R-HSA-5619115
Synthesis of DNA R-HSA-69239
Regulation of PTEN stability and activity R-HSA-8948751
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Hh mutants are degraded by ERAD R-HSA-5362768
ABC transporter disorders R-HSA-5619084
Signaling by ROBO receptors R-HSA-376176
Axon guidance R-HSA-422475
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of mitotic cell cycle R-HSA-453276
TCR signaling R-HSA-202403
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Independent DNA Damage Response R-HSA-69610
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Deubiquitination R-HSA-5688426
Separation of Sister Chromatids R-HSA-2467813
M Phase R-HSA-68886
Hedgehog 'off' state R-HSA-5610787
PTEN Regulation R-HSA-6807070
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX3 R-HSA-8878159
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
RAF/MAP kinase cascade R-HSA-5673001
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of expression of SLITs and ROBOs R-HSA-9010553
C-type lectin receptors (CLRs) R-HSA-5621481
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
DNA Replication R-HSA-69306
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Anaphase R-HSA-68882
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to hypoxia R-HSA-1234174
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
Downstream TCR signaling R-HSA-202424
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX2 R-HSA-8878166
Antigen processing-Cross presentation R-HSA-1236975
Cellular response to chemical stress R-HSA-9711123
Nervous system development R-HSA-9675108
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by WNT R-HSA-195721
Regulation of RUNX3 expression and activity R-HSA-8941858
Immune System R-HSA-168256
G1/S Transition R-HSA-69206
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
MAPK family signaling cascades R-HSA-5683057
DNA Replication Pre-Initiation R-HSA-69002
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH4 R-HSA-9013694
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
Assembly of the pre-replicative complex R-HSA-68867
G2/M Checkpoints R-HSA-69481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
Beta-catenin independent WNT signaling R-HSA-3858494
Nuclear events mediated by NFE2L2 R-HSA-9759194
Programmed Cell Death R-HSA-5357801
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G1 phase and G1/S transition R-HSA-453279
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
Hedgehog 'off' state R-HSA-5610787
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Infectious disease R-HSA-5663205
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of beta-catenin by the destruction complex R-HSA-195253
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
p53-Independent DNA Damage Response R-HSA-69610
G2/M Checkpoints R-HSA-69481
Regulation of Apoptosis R-HSA-169911
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Transition R-HSA-69275
FCERI mediated NF-kB activation R-HSA-2871837
Asymmetric localization of PCP proteins R-HSA-4608870
UCH proteinases R-HSA-5689603
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Gene expression (Transcription) R-HSA-74160
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hh mutants abrogate ligand secretion R-HSA-5387390
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH R-HSA-157118
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Innate Immune System R-HSA-168249
Defective CFTR causes cystic fibrosis R-HSA-5678895
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog ligand biogenesis R-HSA-5358346
Adaptive Immune System R-HSA-1280218
Signaling by the B Cell Receptor (BCR) R-HSA-983705
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism R-HSA-1430728
PTEN Regulation R-HSA-6807070
MAPK family signaling cascades R-HSA-5683057
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of RNA R-HSA-8953854
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX3 R-HSA-8878159
Axon guidance R-HSA-422475
Assembly of the pre-replicative complex R-HSA-68867
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Apoptosis R-HSA-109581
Signaling by WNT R-HSA-195721
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of PTEN stability and activity R-HSA-8948751
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
TCF dependent signaling in response to WNT R-HSA-201681
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Class I MHC mediated antigen processing & presentation R-HSA-983169
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stress R-HSA-2262752
TCR signaling R-HSA-202403
DNA Replication R-HSA-69306
Cellular response to hypoxia R-HSA-1234174
Metabolism of proteins R-HSA-392499
HIV Infection R-HSA-162906
Signaling by Hedgehog R-HSA-5358351
Cell Cycle Checkpoints R-HSA-69620
Vif-mediated degradation of APOBEC3G R-HSA-180585
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Switching of origins to a post-replicative state R-HSA-69052
S Phase R-HSA-69242
Programmed Cell Death R-HSA-5357801
Mitotic G2-G2/M phases R-HSA-453274
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 family signaling R-HSA-446652
Degradation of AXIN R-HSA-4641257
RNA Polymerase II Transcription R-HSA-73857
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Transport of small molecules R-HSA-382551
Signaling by Interleukins R-HSA-449147
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of amino acids and derivatives R-HSA-71291
ABC transporter disorders R-HSA-5619084
PCP/CE pathway R-HSA-4086400
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Synthesis of DNA R-HSA-69239
Intracellular signaling by second messengers R-HSA-9006925
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Developmental Biology R-HSA-1266738
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of RAS by GAPs R-HSA-5658442
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
ABC-family proteins mediated transport R-HSA-382556
DNA Replication Pre-Initiation R-HSA-69002
Disease R-HSA-1643685
Separation of Sister Chromatids R-HSA-2467813
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants are degraded by ERAD R-HSA-5362768
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic Anaphase R-HSA-68882
G1/S Transition R-HSA-69206
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Nervous system development R-HSA-9675108
Cell Cycle, Mitotic R-HSA-69278
ER-Phagosome pathway R-HSA-1236974
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Immune System R-HSA-168256
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism of polyamines R-HSA-351202
PTEN Regulation R-HSA-6807070
Metabolism R-HSA-1430728
Infectious disease R-HSA-5663205
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
Signaling by ROBO receptors R-HSA-376176
Immune System R-HSA-168256
Assembly of the pre-replicative complex R-HSA-68867
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to hypoxia R-HSA-1234174
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of AXIN R-HSA-4641257
Apoptosis R-HSA-109581
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Axon guidance R-HSA-422475
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Interleukin-1 signaling R-HSA-9020702
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transcriptional regulation by RUNX2 R-HSA-8878166
Deubiquitination R-HSA-5688426
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ABC transporter disorders R-HSA-5619084
Signal Transduction R-HSA-162582
Cellular response to chemical stress R-HSA-9711123
Switching of origins to a post-replicative state R-HSA-69052
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
S Phase R-HSA-69242
Degradation of GLI2 by the proteasome R-HSA-5610783
G2/M Transition R-HSA-69275
Metabolism of RNA R-HSA-8953854
Synthesis of DNA R-HSA-69239
Hedgehog 'on' state R-HSA-5632684
DNA Replication R-HSA-69306
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Interleukins R-HSA-449147
Cellular responses to stress R-HSA-2262752
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
ABC-family proteins mediated transport R-HSA-382556
Metabolism of proteins R-HSA-392499
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CLEC7A (Dectin-1) signaling R-HSA-5607764
Orc1 removal from chromatin R-HSA-68949
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Beta-catenin independent WNT signaling R-HSA-3858494
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Transport of small molecules R-HSA-382551
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Hedgehog R-HSA-5358351
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
HIV Infection R-HSA-162906
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G1/S Transition R-HSA-69206
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle R-HSA-1640170
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog 'off' state R-HSA-5610787
ER-Phagosome pathway R-HSA-1236974
Separation of Sister Chromatids R-HSA-2467813
Mitotic G1 phase and G1/S transition R-HSA-453279
TCR signaling R-HSA-202403
G2/M Checkpoints R-HSA-69481
M Phase R-HSA-68886
Neddylation R-HSA-8951664
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hh mutants abrogate ligand secretion R-HSA-5387390
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of polyamines R-HSA-351202
Defective CFTR causes cystic fibrosis R-HSA-5678895
PCP/CE pathway R-HSA-4086400
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Adaptive Immune System R-HSA-1280218
Activation of NF-kappaB in B cells R-HSA-1169091
DNA Replication Pre-Initiation R-HSA-69002
p53-Dependent G1 DNA Damage Response R-HSA-69563
UCH proteinases R-HSA-5689603
p53-Independent DNA Damage Response R-HSA-69610
Generic Transcription Pathway R-HSA-212436
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of DVL R-HSA-4641258
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Innate Immune System R-HSA-168249
Regulation of mitotic cell cycle R-HSA-453276
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stimuli R-HSA-8953897
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by NOTCH R-HSA-157118
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Asymmetric localization of PCP proteins R-HSA-4608870
Programmed Cell Death R-HSA-5357801
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
Hedgehog ligand biogenesis R-HSA-5358346
ER-Phagosome pathway R-HSA-1236974
Signal Transduction R-HSA-162582
Signaling by NOTCH4 R-HSA-9013694
Stabilization of p53 R-HSA-69541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
Cyclin E associated events during G1/S transition R-HSA-69202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Assembly of the pre-replicative complex R-HSA-68867
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI2 by the proteasome R-HSA-5610783
C-type lectin receptors (CLRs) R-HSA-5621481
Intracellular signaling by second messengers R-HSA-9006925
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by Interleukins R-HSA-449147
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Independent DNA Damage Response R-HSA-69610
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic Metaphase and Anaphase R-HSA-2555396
FCERI mediated NF-kB activation R-HSA-2871837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism R-HSA-1430728
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of NF-kappaB in B cells R-HSA-1169091
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Synthesis of DNA R-HSA-69239
Metabolism of amino acids and derivatives R-HSA-71291
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by Hedgehog R-HSA-5358351
Gene expression (Transcription) R-HSA-74160
Regulation of mitotic cell cycle R-HSA-453276
Nuclear events mediated by NFE2L2 R-HSA-9759194
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'off' state R-HSA-5610787
Metabolism of RNA R-HSA-8953854
KEAP1-NFE2L2 pathway R-HSA-9755511
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
Cellular response to chemical stress R-HSA-9711123
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Innate Immune System R-HSA-168249
Transport of small molecules R-HSA-382551
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
PCP/CE pathway R-HSA-4086400
Regulation of expression of SLITs and ROBOs R-HSA-9010553
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cell Cycle Checkpoints R-HSA-69620
Degradation of AXIN R-HSA-4641257
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
Downstream TCR signaling R-HSA-202424
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication Pre-Initiation R-HSA-69002
Beta-catenin independent WNT signaling R-HSA-3858494
MAPK6/MAPK4 signaling R-HSA-5687128
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ABC transporter disorders R-HSA-5619084
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disorders of transmembrane transporters R-HSA-5619115
Immune System R-HSA-168256
Apoptosis R-HSA-109581
Regulation of Apoptosis R-HSA-169911
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Adaptive Immune System R-HSA-1280218
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX2 R-HSA-8878166
Orc1 removal from chromatin R-HSA-68949
Infectious disease R-HSA-5663205
ABC-family proteins mediated transport R-HSA-382556
DNA Replication R-HSA-69306
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCF dependent signaling in response to WNT R-HSA-201681
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
Interleukin-1 family signaling R-HSA-446652
G2/M Checkpoints R-HSA-69481
Cellular response to hypoxia R-HSA-1234174
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants abrogate ligand secretion R-HSA-5387390
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S Transition R-HSA-69206
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
UCH proteinases R-HSA-5689603
TCR signaling R-HSA-202403
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
Axon guidance R-HSA-422475
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by ROBO receptors R-HSA-376176
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Antigen processing-Cross presentation R-HSA-1236975
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog 'on' state R-HSA-5632684
HIV Infection R-HSA-162906
Deubiquitination R-HSA-5688426
Host Interactions of HIV factors R-HSA-162909
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
M Phase R-HSA-68886
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
Class I MHC mediated antigen processing & presentation R-HSA-983169
DNA Replication R-HSA-69306
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCF dependent signaling in response to WNT R-HSA-201681
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
S Phase R-HSA-69242
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Cyclin E associated events during G1/S transition R-HSA-69202
Intracellular signaling by second messengers R-HSA-9006925
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC-family proteins mediated transport R-HSA-382556
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Dependent G1 DNA Damage Response R-HSA-69563
Synthesis of DNA R-HSA-69239
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX3 R-HSA-8878159
Infectious disease R-HSA-5663205
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
ER-Phagosome pathway R-HSA-1236974
Immune System R-HSA-168256
Hedgehog 'on' state R-HSA-5632684
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cellular response to chemical stress R-HSA-9711123
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Neddylation R-HSA-8951664
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK family signaling cascades R-HSA-5683057
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G1 phase and G1/S transition R-HSA-453279
Deubiquitination R-HSA-5688426
Mitotic Anaphase R-HSA-68882
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Programmed Cell Death R-HSA-5357801
Hedgehog 'off' state R-HSA-5610787
Interleukin-1 family signaling R-HSA-446652
Developmental Biology R-HSA-1266738
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of proteins R-HSA-392499
Apoptosis R-HSA-109581
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants are degraded by ERAD R-HSA-5362768
Axon guidance R-HSA-422475
Disorders of transmembrane transporters R-HSA-5619115
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stress R-HSA-2262752
Disease R-HSA-1643685
Signaling by WNT R-HSA-195721
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
TCR signaling R-HSA-202403
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RAS by GAPs R-HSA-5658442
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of polyamines R-HSA-351202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to hypoxia R-HSA-1234174
G2/M Checkpoints R-HSA-69481
Ub-specific processing proteases R-HSA-5689880
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Hedgehog R-HSA-5358351
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of AXIN R-HSA-4641257
Mitotic G2-G2/M phases R-HSA-453274
Regulation of Apoptosis R-HSA-169911
p53-Independent DNA Damage Response R-HSA-69610
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism R-HSA-1430728
G1/S Transition R-HSA-69206
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle R-HSA-1640170
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
PTEN Regulation R-HSA-6807070
G2/M Transition R-HSA-69275
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
FCERI mediated NF-kB activation R-HSA-2871837
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Interleukin-1 signaling R-HSA-9020702
Antigen processing-Cross presentation R-HSA-1236975
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Orc1 removal from chromatin R-HSA-68949
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX2 expression and activity R-HSA-8939902
Post-translational protein modification R-HSA-597592
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of DVL R-HSA-4641258
Switching of origins to a post-replicative state R-HSA-69052
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH R-HSA-157118
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX1 R-HSA-8878171
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Innate Immune System R-HSA-168249
Cell Cycle Checkpoints R-HSA-69620
RAF/MAP kinase cascade R-HSA-5673001
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of PTEN stability and activity R-HSA-8948751
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000087191
NCBI gene (formerly Entrezgene) 5705
GeneCards 9552
HGNC Symbol HGNC:9552
MIM gene 601681
UniProtKB Gene Name P62195
WikiGene 5705
Gene: CA9
Ensembl ID : ENSG00000107159
Description: carbonic anhydrase 9
Gene Synonyms: CAIX,MN
6 APIs:
283 Possible Orthologues:

Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
Cellular response to hypoxia R-HSA-1234174
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Cellular responses to stress R-HSA-2262752
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Cellular response to hypoxia R-HSA-1234174
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Cellular responses to stress R-HSA-2262752
Reversible hydration of carbon dioxide R-HSA-1475029
Cellular response to hypoxia R-HSA-1234174
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Reversible hydration of carbon dioxide R-HSA-1475029
Cellular responses to stress R-HSA-2262752
Cellular response to hypoxia R-HSA-1234174
Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Cellular response to hypoxia R-HSA-1234174
Cellular responses to stress R-HSA-2262752
Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
Reversible hydration of carbon dioxide R-HSA-1475029
Cellular responses to stress R-HSA-2262752
Cellular response to hypoxia R-HSA-1234174
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Cellular responses to stimuli R-HSA-8953897
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Cellular responses to stress R-HSA-2262752
Cellular response to hypoxia R-HSA-1234174
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Cellular responses to stimuli R-HSA-8953897
Reversible hydration of carbon dioxide R-HSA-1475029
Cellular response to hypoxia R-HSA-1234174
Cellular responses to stress R-HSA-2262752
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Cellular response to hypoxia R-HSA-1234174
Metabolism R-HSA-1430728

Expression Atlas ENSG00000107159
NCBI gene (formerly Entrezgene) 768
GeneCards 1383
HGNC Symbol HGNC:1383
MIM gene 603179
UniProtKB Gene Name Q16790
WikiGene 768
Ensembl ID : ENSG00000157445
Description: calcium voltage-gated channel auxiliary subunit alpha2delta 3
Gene Synonyms: ALPHA2DELTA-3,HSA272268
8 APIs:
213 Possible Orthologues:

Neuronal System R-HSA-112316
Presynaptic depolarization and calcium channel opening R-HSA-112308
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Transmission across Chemical Synapses R-HSA-112315
Presynaptic depolarization and calcium channel opening R-HSA-112308
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Presynaptic depolarization and calcium channel opening R-HSA-112308
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Presynaptic depolarization and calcium channel opening R-HSA-112308
Transmission across Chemical Synapses R-HSA-112315
Presynaptic depolarization and calcium channel opening R-HSA-112308
Neuronal System R-HSA-112316
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Presynaptic depolarization and calcium channel opening R-HSA-112308
Presynaptic depolarization and calcium channel opening R-HSA-112308
Neuronal System R-HSA-112316
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Presynaptic depolarization and calcium channel opening R-HSA-112308
Transmission across Chemical Synapses R-HSA-112315
Transmission across Chemical Synapses R-HSA-112315
Presynaptic depolarization and calcium channel opening R-HSA-112308
Neuronal System R-HSA-112316
Neuronal System R-HSA-112316
Transmission across Chemical Synapses R-HSA-112315
Presynaptic depolarization and calcium channel opening R-HSA-112308

Expression Atlas ENSG00000157445
NCBI gene (formerly Entrezgene) 55799
GeneCards 15460
HGNC Symbol HGNC:15460
MIM gene 606399
UniProtKB Gene Name Q8IZS8
WikiGene 55799
Gene: CACNA1S
Ensembl ID : ENSG00000081248
Description: calcium voltage-gated channel subunit alpha1 S
Gene Synonyms: CACNL1A3,CAV1.1,HOKPP,HYPOPP,MHS5
32 APIs:
266 Possible Orthologues:

NCAM1 interactions R-HSA-419037
NCAM1 interactions R-HSA-419037
NCAM signaling for neurite out-growth R-HSA-375165
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Developmental Biology R-HSA-1266738
NCAM1 interactions R-HSA-419037
NCAM signaling for neurite out-growth R-HSA-375165
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
NCAM1 interactions R-HSA-419037
NCAM signaling for neurite out-growth R-HSA-375165
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
NCAM signaling for neurite out-growth R-HSA-375165
NCAM1 interactions R-HSA-419037
Developmental Biology R-HSA-1266738
Developmental Biology R-HSA-1266738
NCAM1 interactions R-HSA-419037
NCAM signaling for neurite out-growth R-HSA-375165
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
NCAM signaling for neurite out-growth R-HSA-375165
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
NCAM signaling for neurite out-growth R-HSA-375165
NCAM1 interactions R-HSA-419037
Developmental Biology R-HSA-1266738
NCAM signaling for neurite out-growth R-HSA-375165
NCAM1 interactions R-HSA-419037
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
NCAM signaling for neurite out-growth R-HSA-375165
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
NCAM1 interactions R-HSA-419037
Axon guidance R-HSA-422475
NCAM signaling for neurite out-growth R-HSA-375165
Developmental Biology R-HSA-1266738
NCAM1 interactions R-HSA-419037
Nervous system development R-HSA-9675108

Expression Atlas ENSG00000081248
NCBI gene (formerly Entrezgene) 779
GeneCards 1397
HGNC Symbol HGNC:1397
MIM gene 114208
MIM morbid 601887
UniProtKB Gene Name Q13698
WikiGene 779
Gene: HTR3D
Ensembl ID : ENSG00000186090
Description: 5-hydroxytryptamine receptor 3D
Gene Synonyms:
10 APIs:
57 Possible Orthologues:

Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neuronal System R-HSA-112316
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Transmission across Chemical Synapses R-HSA-112315
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Neuronal System R-HSA-112316
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transmission across Chemical Synapses R-HSA-112315
Transmission across Chemical Synapses R-HSA-112315
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neuronal System R-HSA-112316

Expression Atlas ENSG00000186090
NCBI gene (formerly Entrezgene) 200909
GeneCards 24004
HGNC Symbol HGNC:24004
MIM gene 610122
UniProtKB Gene Name Q70Z44
WikiGene 200909
Gene: CA2
Ensembl ID : ENSG00000104267
Description: carbonic anhydrase 2
Gene Synonyms: CA-II,CAII,CAR2
10 APIs:
285 Possible Orthologues:

Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
O2/CO2 exchange in erythrocytes R-HSA-1480926
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
Reversible hydration of carbon dioxide R-HSA-1475029
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
O2/CO2 exchange in erythrocytes R-HSA-1480926
Transport of small molecules R-HSA-382551
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Transport of small molecules R-HSA-382551
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
O2/CO2 exchange in erythrocytes R-HSA-1480926
Reversible hydration of carbon dioxide R-HSA-1475029
Transport of small molecules R-HSA-382551
Metabolism R-HSA-1430728
O2/CO2 exchange in erythrocytes R-HSA-1480926
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
Reversible hydration of carbon dioxide R-HSA-1475029
O2/CO2 exchange in erythrocytes R-HSA-1480926
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
O2/CO2 exchange in erythrocytes R-HSA-1480926
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
Reversible hydration of carbon dioxide R-HSA-1475029
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
Transport of small molecules R-HSA-382551
Reversible hydration of carbon dioxide R-HSA-1475029
O2/CO2 exchange in erythrocytes R-HSA-1480926
Metabolism R-HSA-1430728
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
O2/CO2 exchange in erythrocytes R-HSA-1480926
Reversible hydration of carbon dioxide R-HSA-1475029
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
O2/CO2 exchange in erythrocytes R-HSA-1480926
Transport of small molecules R-HSA-382551
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
Metabolism R-HSA-1430728
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
O2/CO2 exchange in erythrocytes R-HSA-1480926
Reversible hydration of carbon dioxide R-HSA-1475029
Transport of small molecules R-HSA-382551

Expression Atlas ENSG00000104267
NCBI gene (formerly Entrezgene) 760
GeneCards 1373
HGNC Symbol HGNC:1373
MIM gene 611492
MIM morbid 259730
UniProtKB Gene Name V9HW21
WikiGene 760
Gene: RPS27A
Ensembl ID : ENSG00000143947
Description: ribosomal protein S27a
Gene Synonyms: S27A,UBA80,UBCEP80
4 APIs:
127 Possible Orthologues:

Autophagy R-HSA-9612973
Regulation of signaling by CBL R-HSA-912631
Toll-like Receptor Cascades R-HSA-168898
Aggrephagy R-HSA-9646399
PCP/CE pathway R-HSA-4086400
Regulation of Apoptosis R-HSA-169911
Class I MHC mediated antigen processing & presentation R-HSA-983169
Switching of origins to a post-replicative state R-HSA-69052
NF-kB is activated and signals survival R-HSA-209560
Adaptive Immune System R-HSA-1280218
Regulation of NF-kappa B signaling R-HSA-9758274
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional Regulation by TP53 R-HSA-3700989
Ion channel transport R-HSA-983712
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism R-HSA-1430728
Suppression of phagosomal maturation R-HSA-9637687
UCH proteinases R-HSA-5689603
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
DNA Replication R-HSA-69306
Disorders of transmembrane transporters R-HSA-5619115
Axon guidance R-HSA-422475
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by TGF-beta Receptor Complex R-HSA-170834
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Membrane Trafficking R-HSA-199991
Budding and maturation of HIV virion R-HSA-162588
Metabolism of carbohydrates R-HSA-71387
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
rRNA processing R-HSA-72312
Eukaryotic Translation Termination R-HSA-72764
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
MyD88 cascade initiated on plasma membrane R-HSA-975871
ABC-family proteins mediated transport R-HSA-382556
Maturation of protein E R-HSA-9694493
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by WNT R-HSA-195721
Diseases of metabolism R-HSA-5668914
IRAK2 mediated activation of TAK1 complex R-HSA-937042
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of TNFR1 signaling R-HSA-5357905
Cellular response to chemical stress R-HSA-9711123
Peptide chain elongation R-HSA-156902
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440
KEAP1-NFE2L2 pathway R-HSA-9755511
Fanconi Anemia Pathway R-HSA-6783310
Cellular Senescence R-HSA-2559583
Homology Directed Repair R-HSA-5693538
Ub-specific processing proteases R-HSA-5689880
Negative regulation of MAPK pathway R-HSA-5675221
DNA Repair R-HSA-73894
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Iron uptake and transport R-HSA-917937
Asparagine N-linked glycosylation R-HSA-446203
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by ROBO receptors R-HSA-376176
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Transcriptional regulation by RUNX3 R-HSA-8878159
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
G1/S DNA Damage Checkpoints R-HSA-69615
Dual Incision in GG-NER R-HSA-5696400
Regulation of mitotic cell cycle R-HSA-453276
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
p75NTR signals via NF-kB R-HSA-193639
SARS-CoV-2 Infection R-HSA-9694516
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metalloprotease DUBs R-HSA-5689901
Diseases of carbohydrate metabolism R-HSA-5663084
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
NRIF signals cell death from the nucleus R-HSA-205043
Ovarian tumor domain proteases R-HSA-5689896
Response of Mtb to phagocytosis R-HSA-9637690
G2/M Checkpoints R-HSA-69481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Influenza Infection R-HSA-168255
Programmed Cell Death R-HSA-5357801
Signaling by NOTCH4 R-HSA-9013694
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Translation R-HSA-72766
Degradation of AXIN R-HSA-4641257
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Regulation of TP53 Degradation R-HSA-6804757
SARS-CoV Infections R-HSA-9679506
Oncogene Induced Senescence R-HSA-2559585
Hedgehog 'off' state R-HSA-5610787
Translesion Synthesis by POLH R-HSA-110320
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
FLT3 Signaling R-HSA-9607240
Post-translational protein modification R-HSA-597592
p53-Independent DNA Damage Response R-HSA-69610
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Viral mRNA Translation R-HSA-192823
ISG15 antiviral mechanism R-HSA-1169408
MyD88 dependent cascade initiated on endosome R-HSA-975155
Transcriptional regulation by RUNX2 R-HSA-8878166
Vif-mediated degradation of APOBEC3G R-HSA-180585
Translation of Structural Proteins R-HSA-9683701
SARS-CoV-2-host interactions R-HSA-9705683
ER Quality Control Compartment (ERQC) R-HSA-901032
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of signaling by CBL R-HSA-912631
NOD1/2 Signaling Pathway R-HSA-168638
Metabolism of amino acids and derivatives R-HSA-71291
Plasma lipoprotein clearance R-HSA-8964043
SARS-CoV-1-host interactions R-HSA-9692914
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Aggrephagy R-HSA-9646399
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495
activated TAK1 mediates p38 MAPK activation R-HSA-450302
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cellular response to starvation R-HSA-9711097
HDR through Homologous Recombination (HRR) R-HSA-5685942
Chaperone Mediated Autophagy R-HSA-9613829
FLT3 signaling by CBL mutants R-HSA-9706377
TNF signaling R-HSA-75893
Listeria monocytogenes entry into host cells R-HSA-8876384
Downregulation of TGF-beta receptor signaling R-HSA-2173788
RNA Polymerase II Transcription R-HSA-73857
Formation of TC-NER Pre-Incision Complex R-HSA-6781823
ABC transporter disorders R-HSA-5619084
MAPK1/MAPK3 signaling R-HSA-5684996
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
Regulated Necrosis R-HSA-5218859
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Myoclonic epilepsy of Lafora R-HSA-3785653
Nervous system development R-HSA-9675108
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Alpha-protein kinase 1 signaling pathway R-HSA-9645460
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX1 R-HSA-8878171
Synthesis of DNA R-HSA-69239
Josephin domain DUBs R-HSA-5689877
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Formation of Incision Complex in GG-NER R-HSA-5696395
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of beta-catenin by the destruction complex R-HSA-195253
Processing of DNA double-strand break ends R-HSA-5693607
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Selective autophagy R-HSA-9663891
Oxidative Stress Induced Senescence R-HSA-2559580
RAS processing R-HSA-9648002
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827
Signaling by NOTCH2 R-HSA-1980145
Host Interactions of HIV factors R-HSA-162909
Cell Cycle R-HSA-1640170
Pexophagy R-HSA-9664873
Immune System R-HSA-168256
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
p75 NTR receptor-mediated signalling R-HSA-193704
Formation of a pool of free 40S subunits R-HSA-72689
Selenocysteine synthesis R-HSA-2408557
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Downregulation of ERBB2 signaling R-HSA-8863795
Generic Transcription Pathway R-HSA-212436
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-1 family signaling R-HSA-446652
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of GLI1 by the proteasome R-HSA-5610780
Vesicle-mediated transport R-HSA-5653656
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
FLT3 signaling in disease R-HSA-9682385
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Deubiquitination R-HSA-5688426
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by ERBB4 R-HSA-1236394
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of RNA R-HSA-8953854
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Signaling by FGFR3 R-HSA-5654741
Clathrin-mediated endocytosis R-HSA-8856828
Negative regulation of FGFR2 signaling R-HSA-5654727
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Selenoamino acid metabolism R-HSA-2408522
RAF/MAP kinase cascade R-HSA-5673001
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
S Phase R-HSA-69242
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Circadian Clock R-HSA-400253
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Regulation of necroptotic cell death R-HSA-5675482
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
Translesion synthesis by POLK R-HSA-5655862
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729
Signaling by NOTCH R-HSA-157118
Glycogen synthesis R-HSA-3322077
Hh mutants are degraded by ERAD R-HSA-5362768
Disease R-HSA-1643685
Stabilization of p53 R-HSA-69541
Amyloid fiber formation R-HSA-977225
Signaling by ERBB2 R-HSA-1227986
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Translesion synthesis by REV1 R-HSA-110312
Vpu mediated degradation of CD4 R-HSA-180534
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
rRNA processing in the nucleus and cytosol R-HSA-8868773
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652
Prevention of phagosomal-lysosomal fusion R-HSA-9636383
Signaling by NOTCH3 R-HSA-9012852
MAPK family signaling cascades R-HSA-5683057
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PCP/CE pathway R-HSA-4086400
Macroautophagy R-HSA-1632852
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stimuli R-HSA-8953897
Death Receptor Signaling R-HSA-73887
G1/S Transition R-HSA-69206
Calnexin/calreticulin cycle R-HSA-901042
Dual incision in TC-NER R-HSA-6782135
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Regulation of FZD by ubiquitination R-HSA-4641263
RIPK1-mediated regulated necrosis R-HSA-5213460
Regulation of RUNX3 expression and activity R-HSA-8941858
Translation initiation complex formation R-HSA-72649
Mitotic Anaphase R-HSA-68882
DNA Double-Strand Break Repair R-HSA-5693532
IRAK1 recruits IKK complex R-HSA-937039
Downregulation of ERBB4 signaling R-HSA-1253288
Termination of translesion DNA synthesis R-HSA-5656169
Transport of small molecules R-HSA-382551
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Spry regulation of FGF signaling R-HSA-1295596
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Cellular response to hypoxia R-HSA-1234174
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by FGFR4 R-HSA-5654743
Maturation of protein E R-HSA-9683683
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by Interleukins R-HSA-449147
Interleukin-1 signaling R-HSA-9020702
Regulation of TP53 Expression and Degradation R-HSA-6806003
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
Defective CFTR causes cystic fibrosis R-HSA-5678895
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Late endosomal microautophagy R-HSA-9615710
Cell Cycle Checkpoints R-HSA-69620
Modulation by Mtb of host immune system R-HSA-9637628
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by EGFR R-HSA-177929
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by Hedgehog R-HSA-5358351
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409
Activation of NF-kappaB in B cells R-HSA-1169091
Late Phase of HIV Life Cycle R-HSA-162599
Toll-like Receptor Cascades R-HSA-168898
Orc1 removal from chromatin R-HSA-68949
Influenza Viral RNA Transcription and Replication R-HSA-168273
Negative regulation of FGFR1 signaling R-HSA-5654726
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313
Assembly of the pre-replicative complex R-HSA-68867
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Interleukin-17 signaling R-HSA-448424
Downstream TCR signaling R-HSA-202424
Separation of Sister Chromatids R-HSA-2467813
HIV Infection R-HSA-162906
TCF dependent signaling in response to WNT R-HSA-201681
DNA Double Strand Break Response R-HSA-5693606
Gene expression (Transcription) R-HSA-74160
Negative regulation of FLT3 R-HSA-9706369
Mitotic G1 phase and G1/S transition R-HSA-453279
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic Metaphase and Anaphase R-HSA-2555396
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
Signaling by MET R-HSA-6806834
DNA Damage Bypass R-HSA-73893
Cyclin D associated events in G1 R-HSA-69231
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Neddylation R-HSA-8951664
Innate Immune System R-HSA-168249
Regulation of PTEN localization R-HSA-8948747
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493
Degradation of DVL R-HSA-4641258
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FCERI mediated NF-kB activation R-HSA-2871837
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Negative regulation of FGFR4 signaling R-HSA-5654733
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cell Cycle, Mitotic R-HSA-69278
Signaling by EGFR in Cancer R-HSA-1643713
DNA Replication Pre-Initiation R-HSA-69002
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by FGFR2 R-HSA-5654738
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Peroxisomal protein import R-HSA-9033241
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Asymmetric localization of PCP proteins R-HSA-4608870
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by PTK6 R-HSA-8848021
Cap-dependent Translation Initiation R-HSA-72737
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Late SARS-CoV-2 Infection Events R-HSA-9772573
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Eukaryotic Translation Initiation R-HSA-72613
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Intracellular signaling by second messengers R-HSA-9006925
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Translation of Structural Proteins R-HSA-9694635
Regulation of TP53 Activity R-HSA-5633007
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Damage Recognition in GG-NER R-HSA-5696394
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
SARS-CoV-1 Infection R-HSA-9678108
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Assembly Of The HIV Virion R-HSA-175474
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Translesion synthesis by POLI R-HSA-5656121
p75NTR recruits signalling complexes R-HSA-209543
Negative regulation of FGFR3 signaling R-HSA-5654732
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Metabolism of proteins R-HSA-392499
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Apoptosis R-HSA-109581
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic G2-G2/M phases R-HSA-453274
Ribosomal scanning and start codon recognition R-HSA-72702
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Interferon Signaling R-HSA-913531
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
G2/M Transition R-HSA-69275
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Protein ubiquitination R-HSA-8852135
Regulation of BACH1 activity R-HSA-9708530
Glycogen storage diseases R-HSA-3229121
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
VLDLR internalisation and degradation R-HSA-8866427
Negative regulation of MET activity R-HSA-6807004
Stimuli-sensing channels R-HSA-2672351
Signaling by FGFR R-HSA-190236
Infectious disease R-HSA-5663205
Developmental Biology R-HSA-1266738
Autophagy R-HSA-9612973
Regulation of PTEN stability and activity R-HSA-8948751
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Nucleotide Excision Repair R-HSA-5696398
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by FGFR1 R-HSA-5654736
HIV Life Cycle R-HSA-162587
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Nonsense-Mediated Decay (NMD) R-HSA-927802
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCR signaling R-HSA-202403
M Phase R-HSA-68886
PTEN Regulation R-HSA-6807070
IKK complex recruitment mediated by RIP1 R-HSA-937041
Cellular responses to stress R-HSA-2262752
Signaling by NOTCH1 R-HSA-1980143
Mitophagy R-HSA-5205647
TGF-beta receptor signaling activates SMADs R-HSA-2173789
MAP kinase activation R-HSA-450294
ER-Phagosome pathway R-HSA-1236974
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Membrane binding and targetting of GAG proteins R-HSA-174490
G1 Phase R-HSA-69236
Protein localization R-HSA-9609507
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PINK1-PRKN Mediated Mitophagy R-HSA-5205685
Glycogen metabolism R-HSA-8982491
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Regulation of TP53 Activity through Methylation R-HSA-6804760
MAPK6/MAPK4 signaling R-HSA-5687128
Eukaryotic Translation Elongation R-HSA-156842
Signaling by NOTCH1 in Cancer R-HSA-2644603
EGFR downregulation R-HSA-182971
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973
Negative regulation of FGFR1 signaling R-HSA-5654726
Circadian Clock R-HSA-400253
Mitophagy R-HSA-5205647
Peroxisomal protein import R-HSA-9033241
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
Stimuli-sensing channels R-HSA-2672351
Signaling by EGFR R-HSA-177929
Translesion synthesis by POLK R-HSA-5655862
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314
DNA Repair R-HSA-73894
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Generic Transcription Pathway R-HSA-212436
Homology Directed Repair R-HSA-5693538
Signaling by Interleukins R-HSA-449147
Vpu mediated degradation of CD4 R-HSA-180534
rRNA processing R-HSA-72312
Intracellular signaling by second messengers R-HSA-9006925
Hh mutants are degraded by ERAD R-HSA-5362768
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
Hedgehog 'off' state R-HSA-5610787
DNA Replication R-HSA-69306
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
p53-Independent DNA Damage Response R-HSA-69610
Signaling by CSF3 (G-CSF) R-HSA-9674555
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Eukaryotic Translation Initiation R-HSA-72613
ER Quality Control Compartment (ERQC) R-HSA-901032
Negative regulation of MET activity R-HSA-6807004
MAP kinase activation R-HSA-450294
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disorders of transmembrane transporters R-HSA-5619115
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle Checkpoints R-HSA-69620
Cyclin D associated events in G1 R-HSA-69231
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110
Mitotic Anaphase R-HSA-68882
Oxidative Stress Induced Senescence R-HSA-2559580
Negative regulation of FLT3 R-HSA-9706369
Negative regulation of FGFR3 signaling R-HSA-5654732
Developmental Biology R-HSA-1266738
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH1 in Cancer R-HSA-2644603
Budding and maturation of HIV virion R-HSA-162588
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Neddylation R-HSA-8951664
Translation initiation complex formation R-HSA-72649
Downstream TCR signaling R-HSA-202424
TNF signaling R-HSA-75893
Signal Transduction R-HSA-162582
Selenocysteine synthesis R-HSA-2408557
Plasma lipoprotein clearance R-HSA-8964043
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Pexophagy R-HSA-9664873
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Damage Recognition in GG-NER R-HSA-5696394
SARS-CoV-2 Infection R-HSA-9694516
Cap-dependent Translation Initiation R-HSA-72737
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Eukaryotic Translation Elongation R-HSA-156842
Toll-like Receptor Cascades R-HSA-168898
Metalloprotease DUBs R-HSA-5689901
Formation of Incision Complex in GG-NER R-HSA-5696395
Infection with Mycobacterium tuberculosis R-HSA-9635486
FCERI mediated NF-kB activation R-HSA-2871837
Maturation of protein E R-HSA-9683683
Regulation of mitotic cell cycle R-HSA-453276
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652
Dual Incision in GG-NER R-HSA-5696400
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stimuli R-HSA-8953897
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Maturation of protein E R-HSA-9694493
Processing of DNA double-strand break ends R-HSA-5693607
Signaling by FGFR2 R-HSA-5654738
Regulation of TP53 Degradation R-HSA-6804757
FLT3 signaling by CBL mutants R-HSA-9706377
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
Membrane binding and targetting of GAG proteins R-HSA-174490
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Gene expression (Transcription) R-HSA-74160
Myoclonic epilepsy of Lafora R-HSA-3785653
Activation of NF-kappaB in B cells R-HSA-1169091
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Ribosomal scanning and start codon recognition R-HSA-72702
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
PTEN Regulation R-HSA-6807070
Signaling by ERBB2 R-HSA-1227986
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Fanconi Anemia Pathway R-HSA-6783310
G1 Phase R-HSA-69236
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by PTK6 R-HSA-8848021
Downregulation of TGF-beta receptor signaling R-HSA-2173788
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Host Interactions of HIV factors R-HSA-162909
Assembly Of The HIV Virion R-HSA-175474
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Regulation of TP53 Activity R-HSA-5633007
Infectious disease R-HSA-5663205
Oncogene Induced Senescence R-HSA-2559585
Response of Mtb to phagocytosis R-HSA-9637690
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Transport of small molecules R-HSA-382551
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by TGFB family members R-HSA-9006936
Regulation of PTEN stability and activity R-HSA-8948751
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Separation of Sister Chromatids R-HSA-2467813
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
S Phase R-HSA-69242
Ion channel transport R-HSA-983712
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
FLT3 signaling in disease R-HSA-9682385
Transcriptional Regulation by TP53 R-HSA-3700989
G2/M Transition R-HSA-69275
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Protein ubiquitination R-HSA-8852135
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Influenza Viral RNA Transcription and Replication R-HSA-168273
Vesicle-mediated transport R-HSA-5653656
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210
Regulation of necroptotic cell death R-HSA-5675482
Regulation of RUNX3 expression and activity R-HSA-8941858
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Listeria monocytogenes entry into host cells R-HSA-8876384
Interleukin-1 signaling R-HSA-9020702
Calnexin/calreticulin cycle R-HSA-901042
Apoptosis R-HSA-109581
Macroautophagy R-HSA-1632852
Immune System R-HSA-168256
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Nucleotide Excision Repair R-HSA-5696398
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI2 by the proteasome R-HSA-5610783
DNA Double Strand Break Response R-HSA-5693606
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Peptide chain elongation R-HSA-156902
Regulation of PTEN localization R-HSA-8948747
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493
Signaling by NOTCH3 R-HSA-9012852
Signaling by MET R-HSA-6806834
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
Late endosomal microautophagy R-HSA-9615710
Downregulation of ERBB4 signaling R-HSA-1253288
NOD1/2 Signaling Pathway R-HSA-168638
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Mitotic Metaphase and Anaphase R-HSA-2555396
Selenoamino acid metabolism R-HSA-2408522
G1/S Transition R-HSA-69206
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
HDR through Homologous Recombination (HRR) R-HSA-5685942
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Orc1 removal from chromatin R-HSA-68949
Diseases of metabolism R-HSA-5668914
Axon guidance R-HSA-422475
Translesion synthesis by POLI R-HSA-5656121
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Death Receptor Signaling R-HSA-73887
Negative regulation of FGFR2 signaling R-HSA-5654727
Cell Cycle, Mitotic R-HSA-69278
Signaling by FGFR3 R-HSA-5654741
Glycogen metabolism R-HSA-8982491
RAS processing R-HSA-9648002
FLT3 Signaling R-HSA-9607240
Degradation of beta-catenin by the destruction complex R-HSA-195253
ABC transporter disorders R-HSA-5619084
Signaling by EGFR in Cancer R-HSA-1643713
Cellular responses to stress R-HSA-2262752
Vif-mediated degradation of APOBEC3G R-HSA-180585
SARS-CoV-1 Infection R-HSA-9678108
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Adaptive Immune System R-HSA-1280218
DNA Replication Pre-Initiation R-HSA-69002
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Regulation of BACH1 activity R-HSA-9708530
Late SARS-CoV-2 Infection Events R-HSA-9772573
p75NTR signals via NF-kB R-HSA-193639
IRAK2 mediated activation of TAK1 complex R-HSA-937042
Regulation of TP53 Activity through Methylation R-HSA-6804760
Ub-specific processing proteases R-HSA-5689880
Innate Immune System R-HSA-168249
Signaling by Hedgehog R-HSA-5358351
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
MAPK family signaling cascades R-HSA-5683057
Signaling by WNT R-HSA-195721
PINK1-PRKN Mediated Mitophagy R-HSA-5205685
Stabilization of p53 R-HSA-69541
DNA Double-Strand Break Repair R-HSA-5693532
Protein localization R-HSA-9609507
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
DNA Damage Bypass R-HSA-73893
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular Senescence R-HSA-2559583
Ovarian tumor domain proteases R-HSA-5689896
ABC-family proteins mediated transport R-HSA-382556
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Eukaryotic Translation Termination R-HSA-72764
Mitotic G2-G2/M phases R-HSA-453274
Diseases of carbohydrate metabolism R-HSA-5663084
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Translesion Synthesis by POLH R-HSA-110320
Suppression of phagosomal maturation R-HSA-9637687
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CLEC7A (Dectin-1) signaling R-HSA-5607764
Aggrephagy R-HSA-9646399
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Signaling by ROBO receptors R-HSA-376176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409
Regulation of FZD by ubiquitination R-HSA-4641263
Metabolism of carbohydrates R-HSA-71387
Signaling by NOTCH1 R-HSA-1980143
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Degradation of DVL R-HSA-4641258
Asparagine N-linked glycosylation R-HSA-446203
MyD88-independent TLR4 cascade R-HSA-166166
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Synthesis of DNA R-HSA-69239
Selective autophagy R-HSA-9663891
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Assembly of the pre-replicative complex R-HSA-68867
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCF dependent signaling in response to WNT R-HSA-201681
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Translation R-HSA-72766
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
ISG15 antiviral mechanism R-HSA-1169408
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle R-HSA-1640170
Signaling by NOTCH2 R-HSA-1980145
Regulation of Apoptosis R-HSA-169911
Membrane Trafficking R-HSA-199991
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Metabolism of RNA R-HSA-8953854
Glycogen synthesis R-HSA-3322077
NRIF signals cell death from the nucleus R-HSA-205043
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
C-type lectin receptors (CLRs) R-HSA-5621481
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827
TCR signaling R-HSA-202403
Signaling by FGFR R-HSA-190236
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
Cellular response to starvation R-HSA-9711097
EGFR downregulation R-HSA-182971
Regulation of TNFR1 signaling R-HSA-5357905
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Cyclin E associated events during G1/S transition R-HSA-69202
HIV Life Cycle R-HSA-162587
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397
Interleukin-17 signaling R-HSA-448424
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Disease R-HSA-1643685
Nonsense-Mediated Decay (NMD) R-HSA-927802
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of TP53 Expression and Degradation R-HSA-6806003
Downregulation of ERBB2 signaling R-HSA-8863795
MyD88 cascade initiated on plasma membrane R-HSA-975871
Translation of Structural Proteins R-HSA-9694635
Nervous system development R-HSA-9675108
Dual incision in TC-NER R-HSA-6782135
Metabolism of amino acids and derivatives R-HSA-71291
ER-Phagosome pathway R-HSA-1236974
Programmed Cell Death R-HSA-5357801
RIPK1-mediated regulated necrosis R-HSA-5213460
Metabolism of proteins R-HSA-392499
rRNA processing in the nucleus and cytosol R-HSA-8868773
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Spry regulation of FGF signaling R-HSA-1295596
PCP/CE pathway R-HSA-4086400
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RAS by GAPs R-HSA-5658442
Influenza Infection R-HSA-168255
Regulation of signaling by CBL R-HSA-912631
Hedgehog 'on' state R-HSA-5632684
Translesion synthesis by REV1 R-HSA-110312
Transcriptional regulation by RUNX1 R-HSA-8878171
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of NF-kappa B signaling R-HSA-9758274
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by ERBB4 R-HSA-1236394
Late Phase of HIV Life Cycle R-HSA-162599
Termination of translesion DNA synthesis R-HSA-5656169
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Post-translational protein modification R-HSA-597592
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Clathrin-mediated endocytosis R-HSA-8856828
Alpha-protein kinase 1 signaling pathway R-HSA-9645460
SARS-CoV-2-host interactions R-HSA-9705683
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Negative regulation of FGFR4 signaling R-HSA-5654733
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
p75 NTR receptor-mediated signalling R-HSA-193704
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Transcriptional regulation by RUNX3 R-HSA-8878159
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Modulation by Mtb of host immune system R-HSA-9637628
IKK complex recruitment mediated by RIP1 R-HSA-937041
Regulation of RUNX2 expression and activity R-HSA-8939902
Formation of a pool of free 40S subunits R-HSA-72689
Degradation of GLI1 by the proteasome R-HSA-5610780
Interferon Signaling R-HSA-913531
SARS-CoV-1-host interactions R-HSA-9692914
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Amyloid fiber formation R-HSA-977225
Iron uptake and transport R-HSA-917937
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
MyD88 dependent cascade initiated on endosome R-HSA-975155
Regulated Necrosis R-HSA-5218859
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Prevention of phagosomal-lysosomal fusion R-HSA-9636383
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by FGFR1 R-HSA-5654736
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Signaling by TGF-beta Receptor Complex R-HSA-170834
Glycogen storage diseases R-HSA-3229121
Viral mRNA Translation R-HSA-192823
Hh mutants abrogate ligand secretion R-HSA-5387390
Chaperone Mediated Autophagy R-HSA-9613829
Josephin domain DUBs R-HSA-5689877
Transcriptional regulation by RUNX2 R-HSA-8878166
IRAK1 recruits IKK complex R-HSA-937039
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
Negative regulation of MAPK pathway R-HSA-5675221
RNA Polymerase II Transcription R-HSA-73857
Translation of Structural Proteins R-HSA-9683701
SARS-CoV Infections R-HSA-9679506
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975
Cellular response to chemical stress R-HSA-9711123
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by FGFR4 R-HSA-5654743
Signaling by NOTCH4 R-HSA-9013694
p75NTR recruits signalling complexes R-HSA-209543
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Switching of origins to a post-replicative state R-HSA-69052
PIP3 activates AKT signaling R-HSA-1257604
NF-kB is activated and signals survival R-HSA-209560
Defective CFTR causes cystic fibrosis R-HSA-5678895
Formation of TC-NER Pre-Incision Complex R-HSA-6781823
HIV Infection R-HSA-162906
VLDLR internalisation and degradation R-HSA-8866427
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
G2/M Checkpoints R-HSA-69481
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to hypoxia R-HSA-1234174
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
Vesicle-mediated transport R-HSA-5653656
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Cell Cycle Checkpoints R-HSA-69620
KEAP1-NFE2L2 pathway R-HSA-9755511
Macroautophagy R-HSA-1632852
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973
Ion channel transport R-HSA-983712
Cyclin E associated events during G1/S transition R-HSA-69202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Axon guidance R-HSA-422475
Membrane binding and targetting of GAG proteins R-HSA-174490
Regulation of NF-kappa B signaling R-HSA-9758274
Host Interactions of HIV factors R-HSA-162909
Signaling by ROBO receptors R-HSA-376176
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Eukaryotic Translation Initiation R-HSA-72613
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
PIP3 activates AKT signaling R-HSA-1257604
Immune System R-HSA-168256
Translation R-HSA-72766
Alpha-protein kinase 1 signaling pathway R-HSA-9645460
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110
Downstream TCR signaling R-HSA-202424
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Intracellular signaling by second messengers R-HSA-9006925
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Clathrin-mediated endocytosis R-HSA-8856828
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of AXIN R-HSA-4641257
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH1 R-HSA-1980143
Nuclear events mediated by NFE2L2 R-HSA-9759194
Formation of Incision Complex in GG-NER R-HSA-5696395
Signaling by FGFR R-HSA-190236
Generic Transcription Pathway R-HSA-212436
PCP/CE pathway R-HSA-4086400
Signaling by FGFR1 R-HSA-5654736
TNF signaling R-HSA-75893
Regulation of PTEN stability and activity R-HSA-8948751
Listeria monocytogenes entry into host cells R-HSA-8876384
activated TAK1 mediates p38 MAPK activation R-HSA-450302
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Late SARS-CoV-2 Infection Events R-HSA-9772573
Cell Cycle, Mitotic R-HSA-69278
p53-Dependent G1 DNA Damage Response R-HSA-69563
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Signaling by CSF3 (G-CSF) R-HSA-9674555
Degradation of GLI2 by the proteasome R-HSA-5610783
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493
IRAK1 recruits IKK complex R-HSA-937039
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Cellular response to starvation R-HSA-9711097
Processing of DNA double-strand break ends R-HSA-5693607
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
NRIF signals cell death from the nucleus R-HSA-205043
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
DNA Double Strand Break Response R-HSA-5693606
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Peptide chain elongation R-HSA-156902
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
FLT3 signaling in disease R-HSA-9682385
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
S Phase R-HSA-69242
Downregulation of ERBB2 signaling R-HSA-8863795
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Signaling by ERBB4 R-HSA-1236394
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
UCH proteinases R-HSA-5689603
Neddylation R-HSA-8951664
Stabilization of p53 R-HSA-69541
TGF-beta receptor signaling activates SMADs R-HSA-2173789
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Cap-dependent Translation Initiation R-HSA-72737
Spry regulation of FGF signaling R-HSA-1295596
MAP kinase activation R-HSA-450294
Signaling by PTK6 R-HSA-8848021
IRAK2 mediated activation of TAK1 complex R-HSA-937042
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of RNA R-HSA-8953854
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Signaling by FGFR4 R-HSA-5654743
rRNA processing R-HSA-72312
Autophagy R-HSA-9612973
Signaling by Interleukins R-HSA-449147
FLT3 Signaling R-HSA-9607240
Membrane Trafficking R-HSA-199991
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Post-translational protein modification R-HSA-597592
Mitotic Metaphase and Anaphase R-HSA-2555396
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Gene expression (Transcription) R-HSA-74160
G1/S Transition R-HSA-69206
FLT3 signaling by CBL mutants R-HSA-9706377
SARS-CoV Infections R-HSA-9679506
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Interleukin-1 family signaling R-HSA-446652
Defective CFTR causes cystic fibrosis R-HSA-5678895
Amyloid fiber formation R-HSA-977225
Signaling by TGF-beta Receptor Complex R-HSA-170834
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cell Cycle R-HSA-1640170
Translesion synthesis by POLK R-HSA-5655862
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Ovarian tumor domain proteases R-HSA-5689896
Myoclonic epilepsy of Lafora R-HSA-3785653
Beta-catenin independent WNT signaling R-HSA-3858494
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of TP53 Expression and Degradation R-HSA-6806003
TCR signaling R-HSA-202403
Asymmetric localization of PCP proteins R-HSA-4608870
Hh mutants are degraded by ERAD R-HSA-5362768
Chaperone Mediated Autophagy R-HSA-9613829
Signaling by ERBB2 R-HSA-1227986
DNA Repair R-HSA-73894
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Synthesis of DNA R-HSA-69239
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495
Cellular responses to stimuli R-HSA-8953897
Ribosomal scanning and start codon recognition R-HSA-72702
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
NF-kB is activated and signals survival R-HSA-209560
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Translesion Synthesis by POLH R-HSA-110320
Peroxisomal protein import R-HSA-9033241
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH2 R-HSA-1980145
DNA Replication R-HSA-69306
Negative regulation of FGFR3 signaling R-HSA-5654732
Transport of small molecules R-HSA-382551
Metabolism of amino acids and derivatives R-HSA-71291
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Interleukin-1 signaling R-HSA-9020702
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Downregulation of ERBB4 signaling R-HSA-1253288
NOD1/2 Signaling Pathway R-HSA-168638
Negative regulation of FGFR4 signaling R-HSA-5654733
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'on' state R-HSA-5632684
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
RAS processing R-HSA-9648002
Signaling by FGFR2 R-HSA-5654738
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Signaling by TGFB family members R-HSA-9006936
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RAS by GAPs R-HSA-5658442
SARS-CoV-2-host interactions R-HSA-9705683
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
Selective autophagy R-HSA-9663891
Signaling by WNT R-HSA-195721
Regulation of Apoptosis R-HSA-169911
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stress R-HSA-2262752
Signaling by NOTCH R-HSA-157118
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Degradation of DVL R-HSA-4641258
Regulated Necrosis R-HSA-5218859
Mitophagy R-HSA-5205647
Translesion synthesis by POLI R-HSA-5656121
Influenza Infection R-HSA-168255
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by MET R-HSA-6806834
Regulation of signaling by CBL R-HSA-912631
SARS-CoV-2 Infection R-HSA-9694516
Hedgehog 'off' state R-HSA-5610787
VLDLR internalisation and degradation R-HSA-8866427
Modulation by Mtb of host immune system R-HSA-9637628
Antigen processing-Cross presentation R-HSA-1236975
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729
Diseases of metabolism R-HSA-5668914
Metabolism of carbohydrates R-HSA-71387
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by FGFR3 R-HSA-5654741
PTEN Regulation R-HSA-6807070
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
HIV Infection R-HSA-162906
Interleukin-17 signaling R-HSA-448424
ABC transporter disorders R-HSA-5619084
Late endosomal microautophagy R-HSA-9615710
p75NTR signals via NF-kB R-HSA-193639
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
DNA Damage Recognition in GG-NER R-HSA-5696394
Suppression of phagosomal maturation R-HSA-9637687
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular response to hypoxia R-HSA-1234174
Downregulation of TGF-beta receptor signaling R-HSA-2173788
Switching of origins to a post-replicative state R-HSA-69052
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Metabolism R-HSA-1430728
Homology Directed Repair R-HSA-5693538
Translation of Structural Proteins R-HSA-9683701
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
Deubiquitination R-HSA-5688426
Mitotic Anaphase R-HSA-68882
Formation of a pool of free 40S subunits R-HSA-72689
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Mitotic G1 phase and G1/S transition R-HSA-453279
Negative regulation of FGFR2 signaling R-HSA-5654727
SARS-CoV-1 Infection R-HSA-9678108
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
HIV Life Cycle R-HSA-162587
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Oncogene Induced Senescence R-HSA-2559585
Negative regulation of NOTCH4 signaling R-HSA-9604323
Separation of Sister Chromatids R-HSA-2467813
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
G2/M Checkpoints R-HSA-69481
Regulation of PTEN localization R-HSA-8948747
MAPK6/MAPK4 signaling R-HSA-5687128
G2/M Transition R-HSA-69275
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Nonsense-Mediated Decay (NMD) R-HSA-927802
SARS-CoV-1-host interactions R-HSA-9692914
Pexophagy R-HSA-9664873
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210
Transcriptional regulation by RUNX1 R-HSA-8878171
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Fanconi Anemia Pathway R-HSA-6783310
Regulation of TP53 Degradation R-HSA-6804757
C-type lectin receptors (CLRs) R-HSA-5621481
EGFR downregulation R-HSA-182971
Signal Transduction R-HSA-162582
Regulation of RUNX2 expression and activity R-HSA-8939902
Prevention of phagosomal-lysosomal fusion R-HSA-9636383
ABC-family proteins mediated transport R-HSA-382556
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Late Phase of HIV Life Cycle R-HSA-162599
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCF dependent signaling in response to WNT R-HSA-201681
Termination of translesion DNA synthesis R-HSA-5656169
Regulation of BACH1 activity R-HSA-9708530
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Assembly of the pre-replicative complex R-HSA-68867
Stimuli-sensing channels R-HSA-2672351
Maturation of protein E R-HSA-9683683
Plasma lipoprotein clearance R-HSA-8964043
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Negative regulation of FGFR1 signaling R-HSA-5654726
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
DNA Replication Pre-Initiation R-HSA-69002
Interferon Signaling R-HSA-913531
Translation of Structural Proteins R-HSA-9694635
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Response of Mtb to phagocytosis R-HSA-9637690
MyD88 dependent cascade initiated on endosome R-HSA-975155
ER Quality Control Compartment (ERQC) R-HSA-901032
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314
Infection with Mycobacterium tuberculosis R-HSA-9635486
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by EGFR R-HSA-177929
Glycogen storage diseases R-HSA-3229121
Formation of TC-NER Pre-Incision Complex R-HSA-6781823
RIPK1-mediated regulated necrosis R-HSA-5213460
Ub-specific processing proteases R-HSA-5689880
Regulation of TP53 Activity through Methylation R-HSA-6804760
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Maturation of protein E R-HSA-9694493
Disease R-HSA-1643685
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
HDR through Homologous Recombination (HRR) R-HSA-5685942
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827
p75NTR recruits signalling complexes R-HSA-209543
Negative regulation of MAPK pathway R-HSA-5675221
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Calnexin/calreticulin cycle R-HSA-901042
Activation of NF-kappaB in B cells R-HSA-1169091
ISG15 antiviral mechanism R-HSA-1169408
Dual Incision in GG-NER R-HSA-5696400
Regulation of FZD by ubiquitination R-HSA-4641263
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
rRNA processing in the nucleus and cytosol R-HSA-8868773
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Orc1 removal from chromatin R-HSA-68949
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by EGFR in Cancer R-HSA-1643713
Regulation of TP53 Activity R-HSA-5633007
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Hh mutants abrogate ligand secretion R-HSA-5387390
PINK1-PRKN Mediated Mitophagy R-HSA-5205685
Circadian Clock R-HSA-400253
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of GLI1 by the proteasome R-HSA-5610780
Glycogen synthesis R-HSA-3322077
FCERI mediated NF-kB activation R-HSA-2871837
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
Eukaryotic Translation Termination R-HSA-72764
Negative regulation of FLT3 R-HSA-9706369
M Phase R-HSA-68886
Translation initiation complex formation R-HSA-72649
Dual incision in TC-NER R-HSA-6782135
Selenocysteine synthesis R-HSA-2408557
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of mitotic cell cycle R-HSA-453276
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88-independent TLR4 cascade R-HSA-166166
Transcriptional regulation by RUNX3 R-HSA-8878159
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652
G1/S DNA Damage Checkpoints R-HSA-69615
ER-Phagosome pathway R-HSA-1236974
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Programmed Cell Death R-HSA-5357801
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
Protein ubiquitination R-HSA-8852135
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Translesion synthesis by REV1 R-HSA-110312
Cellular Senescence R-HSA-2559583
Disorders of transmembrane transporters R-HSA-5619115
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Adaptive Immune System R-HSA-1280218
Hedgehog ligand biogenesis R-HSA-5358346
DNA Double-Strand Break Repair R-HSA-5693532
Cyclin D associated events in G1 R-HSA-69231
Josephin domain DUBs R-HSA-5689877
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Negative regulation of MET activity R-HSA-6807004
Aggrephagy R-HSA-9646399
Iron uptake and transport R-HSA-917937
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313
Selenoamino acid metabolism R-HSA-2408522
Toll-like Receptor Cascades R-HSA-168898
G1 Phase R-HSA-69236
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Viral mRNA Translation R-HSA-192823
DNA Damage Bypass R-HSA-73893
Class I MHC mediated antigen processing & presentation R-HSA-983169
Death Receptor Signaling R-HSA-73887
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Budding and maturation of HIV virion R-HSA-162588
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440
Regulation of TNFR1 signaling R-HSA-5357905
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
IKK complex recruitment mediated by RIP1 R-HSA-937041
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Metalloprotease DUBs R-HSA-5689901
Protein localization R-HSA-9609507
Assembly Of The HIV Virion R-HSA-175474
p53-Independent DNA Damage Response R-HSA-69610
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Asparagine N-linked glycosylation R-HSA-446203
MyD88 cascade initiated on plasma membrane R-HSA-975871
Eukaryotic Translation Elongation R-HSA-156842
Diseases of carbohydrate metabolism R-HSA-5663084
Signaling by NOTCH3 R-HSA-9012852
Cellular response to chemical stress R-HSA-9711123
Infectious disease R-HSA-5663205
Glycogen metabolism R-HSA-8982491
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Regulation of necroptotic cell death R-HSA-5675482
Signaling by NOTCH4 R-HSA-9013694
Influenza Viral RNA Transcription and Replication R-HSA-168273
Metabolism of proteins R-HSA-392499
Nucleotide Excision Repair R-HSA-5696398
Macroautophagy R-HSA-1632852
p75NTR recruits signalling complexes R-HSA-209543
Membrane binding and targetting of GAG proteins R-HSA-174490
Metabolism R-HSA-1430728
Signaling by FGFR1 R-HSA-5654736
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Deubiquitination R-HSA-5688426
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
UCH proteinases R-HSA-5689603
Interferon Signaling R-HSA-913531
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cap-dependent Translation Initiation R-HSA-72737
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by TGF-beta Receptor Complex R-HSA-170834
Circadian Clock R-HSA-400253
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by NOTCH1 R-HSA-1980143
Disorders of transmembrane transporters R-HSA-5619115
HDR through Homologous Recombination (HRR) R-HSA-5685942
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Chaperone Mediated Autophagy R-HSA-9613829
Signaling by FGFR3 R-HSA-5654741
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Intracellular signaling by second messengers R-HSA-9006925
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Apoptosis R-HSA-109581
Signaling by ERBB2 R-HSA-1227986
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Influenza Infection R-HSA-168255
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Interleukin-1 signaling R-HSA-9020702
DNA Double-Strand Break Repair R-HSA-5693532
Negative regulation of MET activity R-HSA-6807004
Ion channel transport R-HSA-983712
MyD88-independent TLR4 cascade R-HSA-166166
Cell Cycle Checkpoints R-HSA-69620
Downregulation of ERBB4 signaling R-HSA-1253288
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
Prevention of phagosomal-lysosomal fusion R-HSA-9636383
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Translesion synthesis by POLI R-HSA-5656121
Metabolism of carbohydrates R-HSA-71387
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by FGFR R-HSA-190236
Processing of DNA double-strand break ends R-HSA-5693607
Termination of translesion DNA synthesis R-HSA-5656169
TCF dependent signaling in response to WNT R-HSA-201681
FLT3 signaling in disease R-HSA-9682385
Ub-specific processing proteases R-HSA-5689880
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Listeria monocytogenes entry into host cells R-HSA-8876384
Translesion synthesis by REV1 R-HSA-110312
Nuclear events mediated by NFE2L2 R-HSA-9759194
Formation of a pool of free 40S subunits R-HSA-72689
Influenza Viral RNA Transcription and Replication R-HSA-168273
KEAP1-NFE2L2 pathway R-HSA-9755511
FCERI mediated NF-kB activation R-HSA-2871837
SARS-CoV-1-host interactions R-HSA-9692914
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314
Degradation of beta-catenin by the destruction complex R-HSA-195253
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Signaling by NOTCH1 in Cancer R-HSA-2644603
Negative regulation of NOTCH4 signaling R-HSA-9604323
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
ER-Phagosome pathway R-HSA-1236974
Negative regulation of FLT3 R-HSA-9706369
Regulation of PTEN localization R-HSA-8948747
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Degradation of GLI1 by the proteasome R-HSA-5610780
TNF signaling R-HSA-75893
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Formation of TC-NER Pre-Incision Complex R-HSA-6781823
Signaling by FGFR2 R-HSA-5654738
NIK-->noncanonical NF-kB signaling R-HSA-5676590
FLT3 Signaling R-HSA-9607240
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Dual incision in TC-NER R-HSA-6782135
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
Glycogen synthesis R-HSA-3322077
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G1 Phase R-HSA-69236
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
NOD1/2 Signaling Pathway R-HSA-168638
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397
Maturation of protein E R-HSA-9683683
Cell Cycle, Mitotic R-HSA-69278
Assembly of the pre-replicative complex R-HSA-68867
Cell Cycle R-HSA-1640170
Death Receptor Signaling R-HSA-73887
Homology Directed Repair R-HSA-5693538
Vesicle-mediated transport R-HSA-5653656
Cellular responses to stress R-HSA-2262752
Alpha-protein kinase 1 signaling pathway R-HSA-9645460
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
IKK complex recruitment mediated by RIP1 R-HSA-937041
Negative regulation of MAPK pathway R-HSA-5675221
Negative regulation of FGFR2 signaling R-HSA-5654727
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by MET R-HSA-6806834
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
SARS-CoV Infections R-HSA-9679506
Hedgehog 'on' state R-HSA-5632684
Regulation of necroptotic cell death R-HSA-5675482
DNA Repair R-HSA-73894
Signaling by NOTCH R-HSA-157118
p53-Dependent G1 DNA Damage Response R-HSA-69563
Neddylation R-HSA-8951664
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Mitotic Metaphase and Anaphase R-HSA-2555396
ABC-family proteins mediated transport R-HSA-382556
Formation of Incision Complex in GG-NER R-HSA-5696395
Suppression of phagosomal maturation R-HSA-9637687
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Eukaryotic Translation Termination R-HSA-72764
Late SARS-CoV-2 Infection Events R-HSA-9772573
Ribosomal scanning and start codon recognition R-HSA-72702
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
HIV Infection R-HSA-162906
Regulation of FZD by ubiquitination R-HSA-4641263
Beta-catenin independent WNT signaling R-HSA-3858494
Protein ubiquitination R-HSA-8852135
Selenocysteine synthesis R-HSA-2408557
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Transcriptional regulation by RUNX1 R-HSA-8878171
Synthesis of DNA R-HSA-69239
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mitotic cell cycle R-HSA-453276
DNA Replication Pre-Initiation R-HSA-69002
Maturation of protein E R-HSA-9694493
CLEC7A (Dectin-1) signaling R-HSA-5607764
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by EGFR in Cancer R-HSA-1643713
Regulation of BACH1 activity R-HSA-9708530
Hedgehog 'off' state R-HSA-5610787
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
Transport of small molecules R-HSA-382551
IRAK2 mediated activation of TAK1 complex R-HSA-937042
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitophagy R-HSA-5205647
EGFR downregulation R-HSA-182971
ISG15 antiviral mechanism R-HSA-1169408
Selenoamino acid metabolism R-HSA-2408522
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Hh mutants abrogate ligand secretion R-HSA-5387390
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313
Gene expression (Transcription) R-HSA-74160
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of NF-kappa B signaling R-HSA-9758274
Degradation of DVL R-HSA-4641258
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
M Phase R-HSA-68886
Regulation of TP53 Expression and Degradation R-HSA-6806003
Defective CFTR causes cystic fibrosis R-HSA-5678895
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Antigen processing-Cross presentation R-HSA-1236975
Peptide chain elongation R-HSA-156902
Dual Incision in GG-NER R-HSA-5696400
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Regulation of TP53 Activity R-HSA-5633007
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Negative regulation of FGFR1 signaling R-HSA-5654726
p75NTR signals via NF-kB R-HSA-193639
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Translation of Structural Proteins R-HSA-9694635
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by WNT R-HSA-195721
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409
Cyclin D associated events in G1 R-HSA-69231
p53-Independent DNA Damage Response R-HSA-69610
Spry regulation of FGF signaling R-HSA-1295596
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by Hedgehog R-HSA-5358351
C-type lectin receptors (CLRs) R-HSA-5621481
Switching of origins to a post-replicative state R-HSA-69052
Class I MHC mediated antigen processing & presentation R-HSA-983169
Iron uptake and transport R-HSA-917937
MAP kinase activation R-HSA-450294
MAPK family signaling cascades R-HSA-5683057
rRNA processing in the nucleus and cytosol R-HSA-8868773
Signaling by PTK6 R-HSA-8848021
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210
Separation of Sister Chromatids R-HSA-2467813
Transcriptional Regulation by TP53 R-HSA-3700989
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
Translation initiation complex formation R-HSA-72649
ER Quality Control Compartment (ERQC) R-HSA-901032
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
G1/S Transition R-HSA-69206
Plasma lipoprotein clearance R-HSA-8964043
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
PCP/CE pathway R-HSA-4086400
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Myoclonic epilepsy of Lafora R-HSA-3785653
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
DNA Double Strand Break Response R-HSA-5693606
Diseases of metabolism R-HSA-5668914
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
PINK1-PRKN Mediated Mitophagy R-HSA-5205685
Cellular response to starvation R-HSA-9711097
Immune System R-HSA-168256
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827
Metalloprotease DUBs R-HSA-5689901
Generic Transcription Pathway R-HSA-212436
Assembly Of The HIV Virion R-HSA-175474
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Vpu mediated degradation of CD4 R-HSA-180534
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
MyD88 cascade initiated on plasma membrane R-HSA-975871
Ovarian tumor domain proteases R-HSA-5689896
Translation of Structural Proteins R-HSA-9683701
Budding and maturation of HIV virion R-HSA-162588
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
Stabilization of p53 R-HSA-69541
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by ERBB4 R-HSA-1236394
Axon guidance R-HSA-422475
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Negative regulation of FGFR3 signaling R-HSA-5654732
Infectious disease R-HSA-5663205
Signaling by NOTCH2 R-HSA-1980145
Josephin domain DUBs R-HSA-5689877
VLDLR internalisation and degradation R-HSA-8866427
Late Phase of HIV Life Cycle R-HSA-162599
Amyloid fiber formation R-HSA-977225
HIV Life Cycle R-HSA-162587
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by EGFR R-HSA-177929
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
IRAK1 recruits IKK complex R-HSA-937039
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK6/MAPK4 signaling R-HSA-5687128
Diseases of carbohydrate metabolism R-HSA-5663084
RAF/MAP kinase cascade R-HSA-5673001
Membrane Trafficking R-HSA-199991
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
Regulation of RAS by GAPs R-HSA-5658442
Mitotic G2-G2/M phases R-HSA-453274
Glycogen metabolism R-HSA-8982491
Interleukin-17 signaling R-HSA-448424
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493
Signaling by ROBO receptors R-HSA-376176
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Oxidative Stress Induced Senescence R-HSA-2559580
Selective autophagy R-HSA-9663891
Programmed Cell Death R-HSA-5357801
G2/M Checkpoints R-HSA-69481
Metabolism of proteins R-HSA-392499
Downstream TCR signaling R-HSA-202424
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973
Translesion synthesis by POLK R-HSA-5655862
ABC transporter disorders R-HSA-5619084
PTEN Regulation R-HSA-6807070
Downregulation of TGF-beta receptor signaling R-HSA-2173788
Regulation of Apoptosis R-HSA-169911
Cellular responses to stimuli R-HSA-8953897
Post-translational protein modification R-HSA-597592
Clathrin-mediated endocytosis R-HSA-8856828
Regulation of TP53 Degradation R-HSA-6804757
Adaptive Immune System R-HSA-1280218
Eukaryotic Translation Initiation R-HSA-72613
NF-kB is activated and signals survival R-HSA-209560
Cellular Senescence R-HSA-2559583
Late endosomal microautophagy R-HSA-9615710
Regulation of TNFR1 signaling R-HSA-5357905
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by FGFR4 R-HSA-5654743
Degradation of AXIN R-HSA-4641257
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Metabolism of amino acids and derivatives R-HSA-71291
S Phase R-HSA-69242
Regulated Necrosis R-HSA-5218859
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Orc1 removal from chromatin R-HSA-68949
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Downregulation of ERBB2 signaling R-HSA-8863795
Cytokine Signaling in Immune system R-HSA-1280215
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Stimuli-sensing channels R-HSA-2672351
RIPK1-mediated regulated necrosis R-HSA-5213460
Translation R-HSA-72766
Autophagy R-HSA-9612973
Signaling by TGFB family members R-HSA-9006936
Signaling by NOTCH3 R-HSA-9012852
Calnexin/calreticulin cycle R-HSA-901042
Viral mRNA Translation R-HSA-192823
Hedgehog ligand biogenesis R-HSA-5358346
SARS-CoV-1 Infection R-HSA-9678108
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SARS-CoV-2-host interactions R-HSA-9705683
Pexophagy R-HSA-9664873
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
rRNA processing R-HSA-72312
Mitotic G1 phase and G1/S transition R-HSA-453279
Response of Mtb to phagocytosis R-HSA-9637690
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440
G1/S DNA Damage Checkpoints R-HSA-69615
Signal Transduction R-HSA-162582
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Glycogen storage diseases R-HSA-3229121
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Oncogene Induced Senescence R-HSA-2559585
Cyclin E associated events during G1/S transition R-HSA-69202
Nonsense-Mediated Decay (NMD) R-HSA-927802
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of PTEN stability and activity R-HSA-8948751
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Innate Immune System R-HSA-168249
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of RNA R-HSA-8953854
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
DNA Damage Recognition in GG-NER R-HSA-5696394
RAS processing R-HSA-9648002
Host Interactions of HIV factors R-HSA-162909
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Fanconi Anemia Pathway R-HSA-6783310
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
DNA Damage Bypass R-HSA-73893
Hh mutants are degraded by ERAD R-HSA-5362768
TCR signaling R-HSA-202403
FLT3 signaling by CBL mutants R-HSA-9706377
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652
Nucleotide Excision Repair R-HSA-5696398
Signaling by NOTCH4 R-HSA-9013694
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Peroxisomal protein import R-HSA-9033241
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by CSF3 (G-CSF) R-HSA-9674555
Regulation of RUNX2 expression and activity R-HSA-8939902
Activation of NF-kappaB in B cells R-HSA-1169091
Eukaryotic Translation Elongation R-HSA-156842
Protein localization R-HSA-9609507
Regulation of TP53 Activity through Methylation R-HSA-6804760
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI2 by the proteasome R-HSA-5610783
Modulation by Mtb of host immune system R-HSA-9637628
Cellular response to chemical stress R-HSA-9711123
Mitotic Anaphase R-HSA-68882
Asparagine N-linked glycosylation R-HSA-446203
SARS-CoV-2 Infection R-HSA-9694516
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Interleukin-1 family signaling R-HSA-446652
Aggrephagy R-HSA-9646399
Translesion Synthesis by POLH R-HSA-110320
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RNA Polymerase II Transcription R-HSA-73857
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Negative regulation of FGFR4 signaling R-HSA-5654733
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Expression and Degradation R-HSA-6806003
SARS-CoV-1 Infection R-HSA-9678108
Amyloid fiber formation R-HSA-977225
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Plasma lipoprotein clearance R-HSA-8964043
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Degradation of beta-catenin by the destruction complex R-HSA-195253
Glycogen synthesis R-HSA-3322077
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Regulation of FZD by ubiquitination R-HSA-4641263
Innate Immune System R-HSA-168249
Translesion Synthesis by POLH R-HSA-110320
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Homology Directed Repair R-HSA-5693538
Ribosomal scanning and start codon recognition R-HSA-72702
Glycogen metabolism R-HSA-8982491
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of NF-kappa B signaling R-HSA-9758274
Switching of origins to a post-replicative state R-HSA-69052
Processing of DNA double-strand break ends R-HSA-5693607
Signaling by EGFR in Cancer R-HSA-1643713
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Mitotic G2-G2/M phases R-HSA-453274
IKK complex recruitment mediated by RIP1 R-HSA-937041
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
Degradation of AXIN R-HSA-4641257
Degradation of DVL R-HSA-4641258
Adaptive Immune System R-HSA-1280218
Vesicle-mediated transport R-HSA-5653656
Cell Cycle R-HSA-1640170
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Regulation of PTEN stability and activity R-HSA-8948751
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of FGFR1 signaling R-HSA-5654726
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Eukaryotic Translation Initiation R-HSA-72613
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
ER-Phagosome pathway R-HSA-1236974
Regulation of TP53 Activity R-HSA-5633007
Regulation of expression of SLITs and ROBOs R-HSA-9010553
rRNA processing R-HSA-72312
EGFR downregulation R-HSA-182971
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Signaling by MET R-HSA-6806834
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
RIPK1-mediated regulated necrosis R-HSA-5213460
Signaling by EGFR R-HSA-177929
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hh mutants are degraded by ERAD R-HSA-5362768
MAP kinase activation R-HSA-450294
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by WNT R-HSA-195721
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Listeria monocytogenes entry into host cells R-HSA-8876384
ABC-family proteins mediated transport R-HSA-382556
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
SARS-CoV-1-host interactions R-HSA-9692914
Cyclin D associated events in G1 R-HSA-69231
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110
Formation of a pool of free 40S subunits R-HSA-72689
Regulation of Apoptosis R-HSA-169911
MAPK6/MAPK4 signaling R-HSA-5687128
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by PTK6 R-HSA-8848021
DNA Double Strand Break Response R-HSA-5693606
Signaling by Interleukins R-HSA-449147
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Ub-specific processing proteases R-HSA-5689880
Infectious disease R-HSA-5663205
Membrane binding and targetting of GAG proteins R-HSA-174490
Regulation of TP53 Degradation R-HSA-6804757
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Signaling by ERBB2 R-HSA-1227986
Nucleotide Excision Repair R-HSA-5696398
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
NIK-->noncanonical NF-kB signaling R-HSA-5676590
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Cytokine Signaling in Immune system R-HSA-1280215
G1/S Transition R-HSA-69206
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of GLI2 by the proteasome R-HSA-5610783
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Glycogen storage diseases R-HSA-3229121
Neddylation R-HSA-8951664
p75NTR signals via NF-kB R-HSA-193639
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Diseases of carbohydrate metabolism R-HSA-5663084
MyD88 dependent cascade initiated on endosome R-HSA-975155
Defective CFTR causes cystic fibrosis R-HSA-5678895
Translation of Structural Proteins R-HSA-9694635
NF-kB is activated and signals survival R-HSA-209560
Gene expression (Transcription) R-HSA-74160
Diseases of metabolism R-HSA-5668914
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by FGFR2 R-HSA-5654738
G2/M Checkpoints R-HSA-69481
Cell Cycle Checkpoints R-HSA-69620
Influenza Infection R-HSA-168255
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Late SARS-CoV-2 Infection Events R-HSA-9772573
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by FGFR1 R-HSA-5654736
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Peptide chain elongation R-HSA-156902
Asparagine N-linked glycosylation R-HSA-446203
Nervous system development R-HSA-9675108
Negative regulation of MAPK pathway R-HSA-5675221
Signal Transduction R-HSA-162582
Signaling by FGFR4 R-HSA-5654743
Suppression of phagosomal maturation R-HSA-9637687
Negative regulation of FLT3 R-HSA-9706369
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of PTEN localization R-HSA-8948747
Signaling by CSF3 (G-CSF) R-HSA-9674555
Late endosomal microautophagy R-HSA-9615710
Hedgehog ligand biogenesis R-HSA-5358346
Translesion synthesis by POLK R-HSA-5655862
Mitotic Anaphase R-HSA-68882
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495
Transport of small molecules R-HSA-382551
Cellular response to chemical stress R-HSA-9711123
Generic Transcription Pathway R-HSA-212436
Asymmetric localization of PCP proteins R-HSA-4608870
FLT3 Signaling R-HSA-9607240
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88-independent TLR4 cascade R-HSA-166166
Metabolism of RNA R-HSA-8953854
Transcriptional regulation by RUNX3 R-HSA-8878159
SARS-CoV-2-host interactions R-HSA-9705683
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by FGFR R-HSA-190236
Maturation of protein E R-HSA-9683683
Metabolism of carbohydrates R-HSA-71387
Modulation by Mtb of host immune system R-HSA-9637628
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Ion channel transport R-HSA-983712
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH1 R-HSA-1980143
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
MAPK1/MAPK3 signaling R-HSA-5684996
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210
Mitophagy R-HSA-5205647
Eukaryotic Translation Elongation R-HSA-156842
Late Phase of HIV Life Cycle R-HSA-162599
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by NOTCH3 R-HSA-9012852
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
RAS processing R-HSA-9648002
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
Cellular responses to stimuli R-HSA-8953897
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Mitotic Metaphase and Anaphase R-HSA-2555396
Post-translational protein modification R-HSA-597592
Influenza Viral RNA Transcription and Replication R-HSA-168273
IRAK2 mediated activation of TAK1 complex R-HSA-937042
Transcriptional regulation by RUNX1 R-HSA-8878171
Negative regulation of FGFR3 signaling R-HSA-5654732
Deubiquitination R-HSA-5688426
FLT3 signaling in disease R-HSA-9682385
Negative regulation of FGFR4 signaling R-HSA-5654733
Interleukin-1 family signaling R-HSA-446652
DNA Replication Pre-Initiation R-HSA-69002
Hedgehog 'on' state R-HSA-5632684
Disorders of transmembrane transporters R-HSA-5619115
Toll-like Receptor Cascades R-HSA-168898
Spry regulation of FGF signaling R-HSA-1295596
Assembly Of The HIV Virion R-HSA-175474
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Iron uptake and transport R-HSA-917937
HIV Life Cycle R-HSA-162587
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulation of RUNX2 expression and activity R-HSA-8939902
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Infection with Mycobacterium tuberculosis R-HSA-9635486
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle, Mitotic R-HSA-69278
Prevention of phagosomal-lysosomal fusion R-HSA-9636383
TCF dependent signaling in response to WNT R-HSA-201681
Josephin domain DUBs R-HSA-5689877
Autophagy R-HSA-9612973
Dual Incision in GG-NER R-HSA-5696400
PCP/CE pathway R-HSA-4086400
Calnexin/calreticulin cycle R-HSA-901042
TNF signaling R-HSA-75893
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
G2/M Transition R-HSA-69275
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of mitotic cell cycle R-HSA-453276
PINK1-PRKN Mediated Mitophagy R-HSA-5205685
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Negative regulation of FGFR2 signaling R-HSA-5654727
Downregulation of TGF-beta receptor signaling R-HSA-2173788
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Maturation of protein E R-HSA-9694493
HDR through Homologous Recombination (HRR) R-HSA-5685942
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FCERI mediated NF-kB activation R-HSA-2871837
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
KEAP1-NFE2L2 pathway R-HSA-9755511
Death Receptor Signaling R-HSA-73887
Budding and maturation of HIV virion R-HSA-162588
Cellular response to starvation R-HSA-9711097
Selenocysteine synthesis R-HSA-2408557
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Apoptosis R-HSA-109581
DNA Damage Bypass R-HSA-73893
Regulation of signaling by CBL R-HSA-912631
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Antigen processing-Cross presentation R-HSA-1236975
Formation of Incision Complex in GG-NER R-HSA-5696395
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by NOTCH2 R-HSA-1980145
Regulation of TNFR1 signaling R-HSA-5357905
Downregulation of ERBB4 signaling R-HSA-1253288
Mitotic G1 phase and G1/S transition R-HSA-453279
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Beta-catenin independent WNT signaling R-HSA-3858494
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Dual incision in TC-NER R-HSA-6782135
Activation of NF-kappaB in B cells R-HSA-1169091
Disease R-HSA-1643685
Clathrin-mediated endocytosis R-HSA-8856828
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Alpha-protein kinase 1 signaling pathway R-HSA-9645460
Signaling by Hedgehog R-HSA-5358351
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975
S Phase R-HSA-69242
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Regulation of BACH1 activity R-HSA-9708530
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Downregulation of ERBB2 signaling R-HSA-8863795
M Phase R-HSA-68886
Protein ubiquitination R-HSA-8852135
Cellular Senescence R-HSA-2559583
Circadian Clock R-HSA-400253
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Regulation of RAS by GAPs R-HSA-5658442
Metabolism R-HSA-1430728
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
rRNA processing in the nucleus and cytosol R-HSA-8868773
Synthesis of DNA R-HSA-69239
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Host Interactions of HIV factors R-HSA-162909
Pexophagy R-HSA-9664873
NOD1/2 Signaling Pathway R-HSA-168638
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Hh mutants abrogate ligand secretion R-HSA-5387390
Chaperone Mediated Autophagy R-HSA-9613829
DNA Repair R-HSA-73894
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Metabolism of proteins R-HSA-392499
Peroxisomal protein import R-HSA-9033241
Signaling by TGFB family members R-HSA-9006936
PIP3 activates AKT signaling R-HSA-1257604
Regulation of necroptotic cell death R-HSA-5675482
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
Selenoamino acid metabolism R-HSA-2408522
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
PTEN Regulation R-HSA-6807070
Nuclear events mediated by NFE2L2 R-HSA-9759194
C-type lectin receptors (CLRs) R-HSA-5621481
Downstream TCR signaling R-HSA-202424
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Regulation of TP53 Activity through Methylation R-HSA-6804760
Intracellular signaling by second messengers R-HSA-9006925
Protein localization R-HSA-9609507
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397
Termination of translesion DNA synthesis R-HSA-5656169
DNA Replication R-HSA-69306
FLT3 signaling by CBL mutants R-HSA-9706377
Macroautophagy R-HSA-1632852
DNA Damage Recognition in GG-NER R-HSA-5696394
VLDLR internalisation and degradation R-HSA-8866427
Negative regulation of NOTCH4 signaling R-HSA-9604323
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of amino acids and derivatives R-HSA-71291
p53-Independent DNA Damage Response R-HSA-69610
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Translation R-HSA-72766
SARS-CoV Infections R-HSA-9679506
Oncogene Induced Senescence R-HSA-2559585
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
DNA Double-Strand Break Repair R-HSA-5693532
RAF/MAP kinase cascade R-HSA-5673001
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by FGFR3 R-HSA-5654741
UCH proteinases R-HSA-5689603
SARS-CoV-2 Infection R-HSA-9694516
Interferon Signaling R-HSA-913531
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Interleukin-1 signaling R-HSA-9020702
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
RNA Polymerase II Transcription R-HSA-73857
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827
Regulated Necrosis R-HSA-5218859
Vpu mediated degradation of CD4 R-HSA-180534
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409
Fanconi Anemia Pathway R-HSA-6783310
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Stimuli-sensing channels R-HSA-2672351
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Assembly of the pre-replicative complex R-HSA-68867
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Translesion synthesis by POLI R-HSA-5656121
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Immune System R-HSA-168256
Translation initiation complex formation R-HSA-72649
Negative regulation of MET activity R-HSA-6807004
HIV Infection R-HSA-162906
Response of Mtb to phagocytosis R-HSA-9637690
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Viral mRNA Translation R-HSA-192823
Nonsense-Mediated Decay (NMD) R-HSA-927802
Interleukin-17 signaling R-HSA-448424
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
Membrane Trafficking R-HSA-199991
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular response to hypoxia R-HSA-1234174
Ovarian tumor domain proteases R-HSA-5689896
Cellular responses to stress R-HSA-2262752
Signaling by ROBO receptors R-HSA-376176
Translation of Structural Proteins R-HSA-9683701
ER Quality Control Compartment (ERQC) R-HSA-901032
Orc1 removal from chromatin R-HSA-68949
Myoclonic epilepsy of Lafora R-HSA-3785653
TCR signaling R-HSA-202403
MAPK family signaling cascades R-HSA-5683057
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Eukaryotic Translation Termination R-HSA-72764
Metalloprotease DUBs R-HSA-5689901
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by ERBB4 R-HSA-1236394
G1 Phase R-HSA-69236
Translesion synthesis by REV1 R-HSA-110312
Formation of TC-NER Pre-Incision Complex R-HSA-6781823
IRAK1 recruits IKK complex R-HSA-937039
Selective autophagy R-HSA-9663891
Developmental Biology R-HSA-1266738
Cap-dependent Translation Initiation R-HSA-72737
ISG15 antiviral mechanism R-HSA-1169408
p75NTR recruits signalling complexes R-HSA-209543
Metabolism R-HSA-1430728
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional Regulation by TP53 R-HSA-3700989
Budding and maturation of HIV virion R-HSA-162588
Metalloprotease DUBs R-HSA-5689901
Cellular response to starvation R-HSA-9711097
Signaling by NOTCH R-HSA-157118
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Hh mutants are degraded by ERAD R-HSA-5362768
DNA Damage Recognition in GG-NER R-HSA-5696394
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Late endosomal microautophagy R-HSA-9615710
Regulation of signaling by CBL R-HSA-912631
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Gene expression (Transcription) R-HSA-74160
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
PINK1-PRKN Mediated Mitophagy R-HSA-5205685
Protein localization R-HSA-9609507
Dual incision in TC-NER R-HSA-6782135
Disease R-HSA-1643685
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
Downregulation of ERBB2 signaling R-HSA-8863795
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Signaling by MET R-HSA-6806834
Negative regulation of FGFR3 signaling R-HSA-5654732
SARS-CoV Infections R-HSA-9679506
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Post-translational protein modification R-HSA-597592
RAS processing R-HSA-9648002
Translation of Structural Proteins R-HSA-9694635
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Negative regulation of MET activity R-HSA-6807004
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210
Maturation of protein E R-HSA-9683683
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by EGFR R-HSA-177929
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Synthesis of DNA R-HSA-69239
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
FLT3 signaling in disease R-HSA-9682385
Suppression of phagosomal maturation R-HSA-9637687
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Cellular response to hypoxia R-HSA-1234174
Glycogen storage diseases R-HSA-3229121
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Asymmetric localization of PCP proteins R-HSA-4608870
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
rRNA processing in the nucleus and cytosol R-HSA-8868773
Maturation of protein E R-HSA-9694493
IRAK1 recruits IKK complex R-HSA-937039
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Spry regulation of FGF signaling R-HSA-1295596
Negative regulation of MAPK pathway R-HSA-5675221
Immune System R-HSA-168256
DNA Repair R-HSA-73894
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by ERBB2 R-HSA-1227986
TCF dependent signaling in response to WNT R-HSA-201681
Eukaryotic Translation Elongation R-HSA-156842
Plasma lipoprotein clearance R-HSA-8964043
Signaling by NOTCH2 R-HSA-1980145
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Chaperone Mediated Autophagy R-HSA-9613829
Peptide chain elongation R-HSA-156902
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Circadian Clock R-HSA-400253
Regulation of PTEN localization R-HSA-8948747
Transcriptional regulation by RUNX1 R-HSA-8878171
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Calnexin/calreticulin cycle R-HSA-901042
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
TCR signaling R-HSA-202403
Generic Transcription Pathway R-HSA-212436
Macroautophagy R-HSA-1632852
p75 NTR receptor-mediated signalling R-HSA-193704
Modulation by Mtb of host immune system R-HSA-9637628
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
Glycogen metabolism R-HSA-8982491
Viral mRNA Translation R-HSA-192823
Regulation of NF-kappa B signaling R-HSA-9758274
p53-Independent DNA Damage Response R-HSA-69610
Iron uptake and transport R-HSA-917937
RNA Polymerase II Transcription R-HSA-73857
EGFR downregulation R-HSA-182971
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by PTK6 R-HSA-8848021
Peroxisomal protein import R-HSA-9033241
Signaling by CSF3 (G-CSF) R-HSA-9674555
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Influenza Infection R-HSA-168255
Axon guidance R-HSA-422475
M Phase R-HSA-68886
VLDLR internalisation and degradation R-HSA-8866427
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973
Nucleotide Excision Repair R-HSA-5696398
G2/M Transition R-HSA-69275
NOD1/2 Signaling Pathway R-HSA-168638
activated TAK1 mediates p38 MAPK activation R-HSA-450302
p75NTR signals via NF-kB R-HSA-193639
DNA Damage Bypass R-HSA-73893
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Translesion Synthesis by POLH R-HSA-110320
Hedgehog 'off' state R-HSA-5610787
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
p75NTR recruits signalling complexes R-HSA-209543
Cyclin D associated events in G1 R-HSA-69231
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Neddylation R-HSA-8951664
Prevention of phagosomal-lysosomal fusion R-HSA-9636383
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440
Negative regulation of FGFR4 signaling R-HSA-5654733
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729
Cell Cycle R-HSA-1640170
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of TP53 Activity R-HSA-5633007
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Glycogen synthesis R-HSA-3322077
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Josephin domain DUBs R-HSA-5689877
Transcriptional regulation by RUNX3 R-HSA-8878159
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Regulation of RAS by GAPs R-HSA-5658442
Processing of DNA double-strand break ends R-HSA-5693607
HIV Infection R-HSA-162906
Signaling by TGF-beta Receptor Complex R-HSA-170834
Asparagine N-linked glycosylation R-HSA-446203
Metabolism of RNA R-HSA-8953854
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by Interleukins R-HSA-449147
Alpha-protein kinase 1 signaling pathway R-HSA-9645460
FLT3 Signaling R-HSA-9607240
Regulation of Apoptosis R-HSA-169911
Signaling by ERBB4 R-HSA-1236394
G2/M Checkpoints R-HSA-69481
Formation of TC-NER Pre-Incision Complex R-HSA-6781823
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493
DNA Double Strand Break Response R-HSA-5693606
Degradation of beta-catenin by the destruction complex R-HSA-195253
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Selenocysteine synthesis R-HSA-2408557
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397
Eukaryotic Translation Termination R-HSA-72764
Signaling by NOTCH1 R-HSA-1980143
Downregulation of TGF-beta receptor signaling R-HSA-2173788
Aggrephagy R-HSA-9646399
Interleukin-17 signaling R-HSA-448424
ABC transporter disorders R-HSA-5619084
Signaling by FGFR R-HSA-190236
Signaling by ROBO receptors R-HSA-376176
Mitotic Anaphase R-HSA-68882
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Clathrin-mediated endocytosis R-HSA-8856828
Myoclonic epilepsy of Lafora R-HSA-3785653
DNA Replication R-HSA-69306
Hedgehog ligand biogenesis R-HSA-5358346
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
MAPK family signaling cascades R-HSA-5683057
Antigen processing-Cross presentation R-HSA-1236975
Host Interactions of HIV factors R-HSA-162909
ER-Phagosome pathway R-HSA-1236974
G1 Phase R-HSA-69236
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827
Negative regulation of FGFR2 signaling R-HSA-5654727
MyD88-independent TLR4 cascade R-HSA-166166
Diseases of carbohydrate metabolism R-HSA-5663084
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of PTEN stability and activity R-HSA-8948751
Stabilization of p53 R-HSA-69541
Selective autophagy R-HSA-9663891
Vesicle-mediated transport R-HSA-5653656
Cellular response to chemical stress R-HSA-9711123
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of GLI2 by the proteasome R-HSA-5610783
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Assembly of the pre-replicative complex R-HSA-68867
Cell Cycle, Mitotic R-HSA-69278
Pexophagy R-HSA-9664873
Regulation of mitotic cell cycle R-HSA-453276
Developmental Biology R-HSA-1266738
Apoptosis R-HSA-109581
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulation of TP53 Activity through Methylation R-HSA-6804760
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Infection with Mycobacterium tuberculosis R-HSA-9635486
Regulation of TNFR1 signaling R-HSA-5357905
Cellular responses to stimuli R-HSA-8953897
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
RAF/MAP kinase cascade R-HSA-5673001
Oxidative Stress Induced Senescence R-HSA-2559580
Regulation of BACH1 activity R-HSA-9708530
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Autophagy R-HSA-9612973
Degradation of AXIN R-HSA-4641257
MAPK6/MAPK4 signaling R-HSA-5687128
Negative regulation of FGFR1 signaling R-HSA-5654726
SARS-CoV-2 Infection R-HSA-9694516
HIV Life Cycle R-HSA-162587
Mitotic Metaphase and Anaphase R-HSA-2555396
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
TGF-beta receptor signaling activates SMADs R-HSA-2173789
FLT3 signaling by CBL mutants R-HSA-9706377
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
HDR through Homologous Recombination (HRR) R-HSA-5685942
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975
MAPK1/MAPK3 signaling R-HSA-5684996
NRIF signals cell death from the nucleus R-HSA-205043
Late Phase of HIV Life Cycle R-HSA-162599
Eukaryotic Translation Initiation R-HSA-72613
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
PTEN Regulation R-HSA-6807070
Downstream TCR signaling R-HSA-202424
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
rRNA processing R-HSA-72312
CLEC7A (Dectin-1) signaling R-HSA-5607764
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of amino acids and derivatives R-HSA-71291
Hh mutants abrogate ligand secretion R-HSA-5387390
Interferon Signaling R-HSA-913531
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
S Phase R-HSA-69242
Ion channel transport R-HSA-983712
Assembly Of The HIV Virion R-HSA-175474
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Deubiquitination R-HSA-5688426
Cell Cycle Checkpoints R-HSA-69620
Signaling by FGFR2 R-HSA-5654738
IRAK2 mediated activation of TAK1 complex R-HSA-937042
Toll-like Receptor Cascades R-HSA-168898
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Double-Strand Break Repair R-HSA-5693532
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TNF signaling R-HSA-75893
Programmed Cell Death R-HSA-5357801
UCH proteinases R-HSA-5689603
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Formation of a pool of free 40S subunits R-HSA-72689
Translesion synthesis by REV1 R-HSA-110312
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitophagy R-HSA-5205647
Class I MHC mediated antigen processing & presentation R-HSA-983169
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Hedgehog 'on' state R-HSA-5632684
Listeria monocytogenes entry into host cells R-HSA-8876384
Nonsense-Mediated Decay (NMD) R-HSA-927802
Formation of Incision Complex in GG-NER R-HSA-5696395
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Oncogene Induced Senescence R-HSA-2559585
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Orc1 removal from chromatin R-HSA-68949
Translesion synthesis by POLI R-HSA-5656121
Amyloid fiber formation R-HSA-977225
Diseases of metabolism R-HSA-5668914
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Signaling by FGFR3 R-HSA-5654741
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Late SARS-CoV-2 Infection Events R-HSA-9772573
Homology Directed Repair R-HSA-5693538
Influenza Viral RNA Transcription and Replication R-HSA-168273
Metabolism of carbohydrates R-HSA-71387
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110
ER Quality Control Compartment (ERQC) R-HSA-901032
PCP/CE pathway R-HSA-4086400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downregulation of ERBB4 signaling R-HSA-1253288
Negative regulation of FLT3 R-HSA-9706369
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495
Response of Mtb to phagocytosis R-HSA-9637690
Termination of translesion DNA synthesis R-HSA-5656169
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular responses to stress R-HSA-2262752
ABC-family proteins mediated transport R-HSA-382556
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
Disorders of transmembrane transporters R-HSA-5619115
Selenoamino acid metabolism R-HSA-2408522
Signaling by FGFR1 R-HSA-5654736
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Membrane binding and targetting of GAG proteins R-HSA-174490
Separation of Sister Chromatids R-HSA-2467813
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409
Regulation of TP53 Expression and Degradation R-HSA-6806003
SARS-CoV-1 Infection R-HSA-9678108
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by TGFB family members R-HSA-9006936
Ribosomal scanning and start codon recognition R-HSA-72702
Transport of small molecules R-HSA-382551
SARS-CoV-2-host interactions R-HSA-9705683
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
MAP kinase activation R-HSA-450294
Interleukin-1 signaling R-HSA-9020702
Fanconi Anemia Pathway R-HSA-6783310
Transcriptional regulation by RUNX2 R-HSA-8878166
NF-kB is activated and signals survival R-HSA-209560
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Vif-mediated degradation of APOBEC3G R-HSA-180585
Translation of Structural Proteins R-HSA-9683701
Translation initiation complex formation R-HSA-72649
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Nuclear events mediated by NFE2L2 R-HSA-9759194
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Regulation of TP53 Degradation R-HSA-6804757
Intracellular signaling by second messengers R-HSA-9006925
Stimuli-sensing channels R-HSA-2672351
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of DVL R-HSA-4641258
Metabolism of proteins R-HSA-392499
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cyclin E associated events during G1/S transition R-HSA-69202
Protein ubiquitination R-HSA-8852135
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic G2-G2/M phases R-HSA-453274
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1 DNA Damage Response R-HSA-69563
MyD88 cascade initiated on plasma membrane R-HSA-975871
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
SARS-CoV-1-host interactions R-HSA-9692914
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Membrane Trafficking R-HSA-199991
Signaling by FGFR4 R-HSA-5654743
Signaling by NOTCH4 R-HSA-9013694
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Regulation of necroptotic cell death R-HSA-5675482
Signaling by NOTCH3 R-HSA-9012852
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
RIPK1-mediated regulated necrosis R-HSA-5213460
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of FZD by ubiquitination R-HSA-4641263
Signaling by WNT R-HSA-195721
Translation R-HSA-72766
Nervous system development R-HSA-9675108
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signaling by Hedgehog R-HSA-5358351
Cellular Senescence R-HSA-2559583
FCERI mediated NF-kB activation R-HSA-2871837
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
G1/S Transition R-HSA-69206
Ovarian tumor domain proteases R-HSA-5689896
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Beta-catenin independent WNT signaling R-HSA-3858494
Regulated Necrosis R-HSA-5218859
DNA Replication Pre-Initiation R-HSA-69002
Cap-dependent Translation Initiation R-HSA-72737
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
Translesion synthesis by POLK R-HSA-5655862
Death Receptor Signaling R-HSA-73887
ISG15 antiviral mechanism R-HSA-1169408
Activation of NF-kappaB in B cells R-HSA-1169091
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Dual Incision in GG-NER R-HSA-5696400
IKK complex recruitment mediated by RIP1 R-HSA-937041
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
DNA Damage Recognition in GG-NER R-HSA-5696394
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397
Mitotic G2-G2/M phases R-HSA-453274
Influenza Viral RNA Transcription and Replication R-HSA-168273
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Regulation of mitotic cell cycle R-HSA-453276
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Developmental Biology R-HSA-1266738
Cyclin E associated events during G1/S transition R-HSA-69202
Membrane binding and targetting of GAG proteins R-HSA-174490
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Ovarian tumor domain proteases R-HSA-5689896
Asymmetric localization of PCP proteins R-HSA-4608870
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of RNA R-HSA-8953854
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Translesion synthesis by POLK R-HSA-5655862
Assembly of the pre-replicative complex R-HSA-68867
Cellular responses to stress R-HSA-2262752
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210
Myoclonic epilepsy of Lafora R-HSA-3785653
Formation of a pool of free 40S subunits R-HSA-72689
DNA Double Strand Break Response R-HSA-5693606
TCF dependent signaling in response to WNT R-HSA-201681
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G2/M Transition R-HSA-69275
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Aggrephagy R-HSA-9646399
NF-kB is activated and signals survival R-HSA-209560
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PIP3 activates AKT signaling R-HSA-1257604
Regulation of TP53 Expression and Degradation R-HSA-6806003
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
p53-Independent DNA Damage Response R-HSA-69610
Eukaryotic Translation Elongation R-HSA-156842
Translesion Synthesis by POLH R-HSA-110320
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Ion channel transport R-HSA-983712
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Synthesis of DNA R-HSA-69239
Class I MHC mediated antigen processing & presentation R-HSA-983169
Late endosomal microautophagy R-HSA-9615710
Disease R-HSA-1643685
Negative regulation of FLT3 R-HSA-9706369
Degradation of GLI2 by the proteasome R-HSA-5610783
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
MAPK1/MAPK3 signaling R-HSA-5684996
Axon guidance R-HSA-422475
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
M Phase R-HSA-68886
Regulation of TP53 Degradation R-HSA-6804757
Metabolism of proteins R-HSA-392499
Maturation of protein E R-HSA-9683683
Metabolism of amino acids and derivatives R-HSA-71291
Vesicle-mediated transport R-HSA-5653656
G1/S DNA Damage Checkpoints R-HSA-69615
Negative regulation of MET activity R-HSA-6807004
Response of Mtb to phagocytosis R-HSA-9637690
Signaling by TGFB family members R-HSA-9006936
NRIF signals cell death from the nucleus R-HSA-205043
Translesion synthesis by POLI R-HSA-5656121
Signal Transduction R-HSA-162582
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Negative regulation of MAPK pathway R-HSA-5675221
Generic Transcription Pathway R-HSA-212436
Antigen processing-Cross presentation R-HSA-1236975
Downregulation of ERBB4 signaling R-HSA-1253288
Peptide chain elongation R-HSA-156902
Nucleotide Excision Repair R-HSA-5696398
Mitotic G1 phase and G1/S transition R-HSA-453279
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Cap-dependent Translation Initiation R-HSA-72737
DNA Double-Strand Break Repair R-HSA-5693532
Formation of TC-NER Pre-Incision Complex R-HSA-6781823
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Homology Directed Repair R-HSA-5693538
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Switching of origins to a post-replicative state R-HSA-69052
Selective autophagy R-HSA-9663891
Cellular responses to stimuli R-HSA-8953897
Degradation of DVL R-HSA-4641258
FCERI mediated NF-kB activation R-HSA-2871837
Negative regulation of FGFR4 signaling R-HSA-5654733
Host Interactions of HIV factors R-HSA-162909
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
Gene expression (Transcription) R-HSA-74160
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Iron uptake and transport R-HSA-917937
Regulation of RUNX2 expression and activity R-HSA-8939902
Ribosomal scanning and start codon recognition R-HSA-72702
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409
Downregulation of ERBB2 signaling R-HSA-8863795
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Programmed Cell Death R-HSA-5357801
Glycogen metabolism R-HSA-8982491
Metabolism of carbohydrates R-HSA-71387
SARS-CoV-2 Infection R-HSA-9694516
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
rRNA processing in the nucleus and cytosol R-HSA-8868773
Fanconi Anemia Pathway R-HSA-6783310
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Chaperone Mediated Autophagy R-HSA-9613829
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of TP53 Activity through Methylation R-HSA-6804760
Signaling by ERBB4 R-HSA-1236394
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signaling by TGF-beta Receptor Complex R-HSA-170834
ER Quality Control Compartment (ERQC) R-HSA-901032
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
SARS-CoV-1 Infection R-HSA-9678108
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652
Signaling by FGFR R-HSA-190236
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Nonsense-Mediated Decay (NMD) R-HSA-927802
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Cellular response to starvation R-HSA-9711097
SARS-CoV-1-host interactions R-HSA-9692914
FLT3 signaling by CBL mutants R-HSA-9706377
VLDLR internalisation and degradation R-HSA-8866427
G1/S Transition R-HSA-69206
Regulation of signaling by CBL R-HSA-912631
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by FGFR1 R-HSA-5654736
DNA Replication Pre-Initiation R-HSA-69002
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493
Selenoamino acid metabolism R-HSA-2408522
Defective CFTR causes cystic fibrosis R-HSA-5678895
Prevention of phagosomal-lysosomal fusion R-HSA-9636383
Signaling by FGFR3 R-HSA-5654741
Transcriptional regulation by RUNX2 R-HSA-8878166
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Infection with Mycobacterium tuberculosis R-HSA-9635486
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Regulation of PTEN localization R-HSA-8948747
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Budding and maturation of HIV virion R-HSA-162588
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cytokine Signaling in Immune system R-HSA-1280215
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314
Plasma lipoprotein clearance R-HSA-8964043
DNA Repair R-HSA-73894
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 signaling R-HSA-9020702
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Dual incision in TC-NER R-HSA-6782135
Signaling by NOTCH1 R-HSA-1980143
Transport of small molecules R-HSA-382551
Oncogene Induced Senescence R-HSA-2559585
MAPK family signaling cascades R-HSA-5683057
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional Regulation by TP53 R-HSA-3700989
Disorders of transmembrane transporters R-HSA-5619115
NOD1/2 Signaling Pathway R-HSA-168638
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Selenocysteine synthesis R-HSA-2408557
Metabolism R-HSA-1430728
Signaling by PTK6 R-HSA-8848021
Diseases of carbohydrate metabolism R-HSA-5663084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
MyD88-independent TLR4 cascade R-HSA-166166
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313
HIV Infection R-HSA-162906
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Regulation of FZD by ubiquitination R-HSA-4641263
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
G2/M Checkpoints R-HSA-69481
Cellular response to hypoxia R-HSA-1234174
Cellular Senescence R-HSA-2559583
Calnexin/calreticulin cycle R-HSA-901042
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Peroxisomal protein import R-HSA-9033241
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Nervous system development R-HSA-9675108
Hedgehog 'on' state R-HSA-5632684
Translesion synthesis by REV1 R-HSA-110312
Regulation of TNFR1 signaling R-HSA-5357905
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
RNA Polymerase II Transcription R-HSA-73857
Regulation of Apoptosis R-HSA-169911
Cellular response to chemical stress R-HSA-9711123
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Regulation of TP53 Activity R-HSA-5633007
Signaling by FGFR2 R-HSA-5654738
Neddylation R-HSA-8951664
SARS-CoV-2-host interactions R-HSA-9705683
Apoptosis R-HSA-109581
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
KEAP1-NFE2L2 pathway R-HSA-9755511
G1 Phase R-HSA-69236
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cell Cycle, Mitotic R-HSA-69278
IRAK2 mediated activation of TAK1 complex R-HSA-937042
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Translation R-HSA-72766
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Dual Incision in GG-NER R-HSA-5696400
Signaling by ERBB2 R-HSA-1227986
Regulation of necroptotic cell death R-HSA-5675482
Ub-specific processing proteases R-HSA-5689880
Assembly Of The HIV Virion R-HSA-175474
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Eukaryotic Translation Termination R-HSA-72764
Separation of Sister Chromatids R-HSA-2467813
Viral mRNA Translation R-HSA-192823
Late SARS-CoV-2 Infection Events R-HSA-9772573
Modulation by Mtb of host immune system R-HSA-9637628
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
EGFR downregulation R-HSA-182971
Mitotic Anaphase R-HSA-68882
IRAK1 recruits IKK complex R-HSA-937039
Signaling by CSF3 (G-CSF) R-HSA-9674555
Death Receptor Signaling R-HSA-73887
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p75 NTR receptor-mediated signalling R-HSA-193704
Macroautophagy R-HSA-1632852
MyD88 cascade initiated on plasma membrane R-HSA-975871
Orc1 removal from chromatin R-HSA-68949
HDR through Homologous Recombination (HRR) R-HSA-5685942
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Pexophagy R-HSA-9664873
Signaling by NOTCH4 R-HSA-9013694
Signaling by EGFR R-HSA-177929
TNF signaling R-HSA-75893
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Interferon Signaling R-HSA-913531
Cyclin D associated events in G1 R-HSA-69231
Innate Immune System R-HSA-168249
Vpu mediated degradation of CD4 R-HSA-180534
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Protein ubiquitination R-HSA-8852135
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by Interleukins R-HSA-449147
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
FLT3 signaling in disease R-HSA-9682385
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Stabilization of p53 R-HSA-69541
Spry regulation of FGF signaling R-HSA-1295596
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by NOTCH2 R-HSA-1980145
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495
Immune System R-HSA-168256
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Hedgehog ligand biogenesis R-HSA-5358346
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973
Diseases of metabolism R-HSA-5668914
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Membrane Trafficking R-HSA-199991
Termination of translesion DNA synthesis R-HSA-5656169
Downregulation of TGF-beta receptor signaling R-HSA-2173788
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitophagy R-HSA-5205647
Mitotic Metaphase and Anaphase R-HSA-2555396
Hedgehog 'off' state R-HSA-5610787
Eukaryotic Translation Initiation R-HSA-72613
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by WNT R-HSA-195721
Regulation of RAS by GAPs R-HSA-5658442
RIPK1-mediated regulated necrosis R-HSA-5213460
Negative regulation of FGFR2 signaling R-HSA-5654727
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Josephin domain DUBs R-HSA-5689877
Protein localization R-HSA-9609507
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Infectious disease R-HSA-5663205
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Translation of Structural Proteins R-HSA-9683701
Hh mutants abrogate ligand secretion R-HSA-5387390
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
rRNA processing R-HSA-72312
MAP kinase activation R-HSA-450294
ABC transporter disorders R-HSA-5619084
p75NTR signals via NF-kB R-HSA-193639
Formation of Incision Complex in GG-NER R-HSA-5696395
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Regulation of NF-kappa B signaling R-HSA-9758274
Degradation of AXIN R-HSA-4641257
Signaling by NOTCH R-HSA-157118
ISG15 antiviral mechanism R-HSA-1169408
Transcriptional regulation by RUNX3 R-HSA-8878159
CLEC7A (Dectin-1) signaling R-HSA-5607764
Negative regulation of FGFR1 signaling R-HSA-5654726
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
Asparagine N-linked glycosylation R-HSA-446203
Stimuli-sensing channels R-HSA-2672351
Regulated Necrosis R-HSA-5218859
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
IKK complex recruitment mediated by RIP1 R-HSA-937041
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Listeria monocytogenes entry into host cells R-HSA-8876384
Late Phase of HIV Life Cycle R-HSA-162599
Circadian Clock R-HSA-400253
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Signaling by NOTCH3 R-HSA-9012852
Influenza Infection R-HSA-168255
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Interleukin-17 signaling R-HSA-448424
PTEN Regulation R-HSA-6807070
Vif-mediated degradation of APOBEC3G R-HSA-180585
ER-Phagosome pathway R-HSA-1236974
Maturation of protein E R-HSA-9694493
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
FLT3 Signaling R-HSA-9607240
Autophagy R-HSA-9612973
Glycogen synthesis R-HSA-3322077
Signaling by ROBO receptors R-HSA-376176
Deubiquitination R-HSA-5688426
Amyloid fiber formation R-HSA-977225
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Post-translational protein modification R-HSA-597592
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Clathrin-mediated endocytosis R-HSA-8856828
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by Hedgehog R-HSA-5358351
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
Intracellular signaling by second messengers R-HSA-9006925
Signaling by MET R-HSA-6806834
Suppression of phagosomal maturation R-HSA-9637687
TCR signaling R-HSA-202403
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RAS processing R-HSA-9648002
DNA Replication R-HSA-69306
Negative regulation of FGFR3 signaling R-HSA-5654732
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Interleukin-1 family signaling R-HSA-446652
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
HIV Life Cycle R-HSA-162587
p75NTR recruits signalling complexes R-HSA-209543
UCH proteinases R-HSA-5689603
Glycogen storage diseases R-HSA-3229121
SARS-CoV Infections R-HSA-9679506
PINK1-PRKN Mediated Mitophagy R-HSA-5205685
PCP/CE pathway R-HSA-4086400
Processing of DNA double-strand break ends R-HSA-5693607
Signaling by FGFR4 R-HSA-5654743
Alpha-protein kinase 1 signaling pathway R-HSA-9645460
Hh mutants are degraded by ERAD R-HSA-5362768
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Translation initiation complex formation R-HSA-72649
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Downstream TCR signaling R-HSA-202424
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle Checkpoints R-HSA-69620
Beta-catenin independent WNT signaling R-HSA-3858494
Cell Cycle R-HSA-1640170
Metalloprotease DUBs R-HSA-5689901
S Phase R-HSA-69242
DNA Damage Bypass R-HSA-73893
ABC-family proteins mediated transport R-HSA-382556
Regulation of BACH1 activity R-HSA-9708530
Translation of Structural Proteins R-HSA-9694635
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Adaptive Immune System R-HSA-1280218
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH1 R-HSA-1980143
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Clathrin-mediated endocytosis R-HSA-8856828
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Metabolism of carbohydrates R-HSA-71387
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Transcriptional regulation by RUNX3 R-HSA-8878159
Hh mutants are degraded by ERAD R-HSA-5362768
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll-like Receptor Cascades R-HSA-168898
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Response of Mtb to phagocytosis R-HSA-9637690
Post-translational protein modification R-HSA-597592
Signaling by FGFR4 R-HSA-5654743
Diseases of carbohydrate metabolism R-HSA-5663084
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Iron uptake and transport R-HSA-917937
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
Alpha-protein kinase 1 signaling pathway R-HSA-9645460
PTEN Regulation R-HSA-6807070
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of Apoptosis R-HSA-169911
Chaperone Mediated Autophagy R-HSA-9613829
Signaling by EGFR in Cancer R-HSA-1643713
Transcriptional regulation by RUNX2 R-HSA-8878166
Ub-specific processing proteases R-HSA-5689880
Signaling by NOTCH1 in Cancer R-HSA-2644603
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by NOTCH3 R-HSA-9012852
Amyloid fiber formation R-HSA-977225
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by Hedgehog R-HSA-5358351
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Eukaryotic Translation Initiation R-HSA-72613
Interleukin-1 signaling R-HSA-9020702
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Vpu mediated degradation of CD4 R-HSA-180534
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Regulation of RAS by GAPs R-HSA-5658442
Metabolism R-HSA-1430728
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
Negative regulation of FGFR3 signaling R-HSA-5654732
Regulation of TP53 Expression and Degradation R-HSA-6806003
SARS-CoV-1-host interactions R-HSA-9692914
Adaptive Immune System R-HSA-1280218
Asparagine N-linked glycosylation R-HSA-446203
Diseases of metabolism R-HSA-5668914
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495
Intracellular signaling by second messengers R-HSA-9006925
Peptide chain elongation R-HSA-156902
FLT3 signaling by CBL mutants R-HSA-9706377
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Oncogene Induced Senescence R-HSA-2559585
Formation of Incision Complex in GG-NER R-HSA-5696395
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of TP53 Activity R-HSA-5633007
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Defective CFTR causes cystic fibrosis R-HSA-5678895
Autophagy R-HSA-9612973
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Calnexin/calreticulin cycle R-HSA-901042
RAF/MAP kinase cascade R-HSA-5673001
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Generic Transcription Pathway R-HSA-212436
Signaling by FGFR1 R-HSA-5654736
DNA Damage Recognition in GG-NER R-HSA-5696394
PINK1-PRKN Mediated Mitophagy R-HSA-5205685
Orc1 removal from chromatin R-HSA-68949
TCF dependent signaling in response to WNT R-HSA-201681
MAPK1/MAPK3 signaling R-HSA-5684996
HIV Infection R-HSA-162906
EGFR downregulation R-HSA-182971
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of signaling by CBL R-HSA-912631
Transport of small molecules R-HSA-382551
Influenza Viral RNA Transcription and Replication R-HSA-168273
SARS-CoV-2 Infection R-HSA-9694516
Cell Cycle, Mitotic R-HSA-69278
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210
Negative regulation of FGFR1 signaling R-HSA-5654726
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
CLEC7A (Dectin-1) signaling R-HSA-5607764
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SARS-CoV-2-host interactions R-HSA-9705683
Translesion synthesis by REV1 R-HSA-110312
Negative regulation of FLT3 R-HSA-9706369
Regulation of TNFR1 signaling R-HSA-5357905
NF-kB is activated and signals survival R-HSA-209560
Myoclonic epilepsy of Lafora R-HSA-3785653
Neddylation R-HSA-8951664
Apoptosis R-HSA-109581
Protein localization R-HSA-9609507
Late Phase of HIV Life Cycle R-HSA-162599
Suppression of phagosomal maturation R-HSA-9637687
Cell Cycle R-HSA-1640170
Translesion synthesis by POLK R-HSA-5655862
Synthesis of DNA R-HSA-69239
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
RIPK1-mediated regulated necrosis R-HSA-5213460
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Signaling by TGF-beta Receptor Complex R-HSA-170834
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110
Infection with Mycobacterium tuberculosis R-HSA-9635486
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Programmed Cell Death R-HSA-5357801
Cellular response to starvation R-HSA-9711097
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493
Mitotic Metaphase and Anaphase R-HSA-2555396
IRAK2 mediated activation of TAK1 complex R-HSA-937042
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
PCP/CE pathway R-HSA-4086400
Peroxisomal protein import R-HSA-9033241
Signaling by NOTCH R-HSA-157118
Innate Immune System R-HSA-168249
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by ROBO receptors R-HSA-376176
Dual Incision in GG-NER R-HSA-5696400
Nucleotide Excision Repair R-HSA-5696398
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409
Vesicle-mediated transport R-HSA-5653656
Switching of origins to a post-replicative state R-HSA-69052
Disorders of transmembrane transporters R-HSA-5619115
Downstream TCR signaling R-HSA-202424
Membrane Trafficking R-HSA-199991
Formation of a pool of free 40S subunits R-HSA-72689
Translation R-HSA-72766
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
Signaling by FGFR2 R-HSA-5654738
FLT3 Signaling R-HSA-9607240
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Signaling by TGFB family members R-HSA-9006936
NOD1/2 Signaling Pathway R-HSA-168638
Viral mRNA Translation R-HSA-192823
Cyclin E associated events during G1/S transition R-HSA-69202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Separation of Sister Chromatids R-HSA-2467813
Homology Directed Repair R-HSA-5693538
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
IRAK1 recruits IKK complex R-HSA-937039
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cellular response to chemical stress R-HSA-9711123
Selenoamino acid metabolism R-HSA-2408522
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
HDR through Homologous Recombination (HRR) R-HSA-5685942
Regulation of mitotic cell cycle R-HSA-453276
Cyclin D associated events in G1 R-HSA-69231
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
Ribosomal scanning and start codon recognition R-HSA-72702
Signaling by WNT R-HSA-195721
Metabolism of proteins R-HSA-392499
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ion channel transport R-HSA-983712
DNA Replication Pre-Initiation R-HSA-69002
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Cellular response to hypoxia R-HSA-1234174
Death Receptor Signaling R-HSA-73887
PIP3 activates AKT signaling R-HSA-1257604
Translesion synthesis by POLI R-HSA-5656121
Fanconi Anemia Pathway R-HSA-6783310
HIV Life Cycle R-HSA-162587
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
Transcriptional regulation by RUNX1 R-HSA-8878171
Immune System R-HSA-168256
Regulation of PTEN stability and activity R-HSA-8948751
Stabilization of p53 R-HSA-69541
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by Interleukins R-HSA-449147
Signaling by EGFR R-HSA-177929
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
Signaling by FGFR R-HSA-190236
G1/S DNA Damage Checkpoints R-HSA-69615
ER Quality Control Compartment (ERQC) R-HSA-901032
Deubiquitination R-HSA-5688426
RNA Polymerase II Transcription R-HSA-73857
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Macroautophagy R-HSA-1632852
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
Cellular responses to stress R-HSA-2262752
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729
Assembly Of The HIV Virion R-HSA-175474
G2/M Checkpoints R-HSA-69481
Josephin domain DUBs R-HSA-5689877
Plasma lipoprotein clearance R-HSA-8964043
Vif-mediated degradation of APOBEC3G R-HSA-180585
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
SARS-CoV Infections R-HSA-9679506
Negative regulation of MET activity R-HSA-6807004
Hedgehog 'off' state R-HSA-5610787
DNA Double-Strand Break Repair R-HSA-5693532
Circadian Clock R-HSA-400253
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Infectious disease R-HSA-5663205
Cellular Senescence R-HSA-2559583
Listeria monocytogenes entry into host cells R-HSA-8876384
Modulation by Mtb of host immune system R-HSA-9637628
Late SARS-CoV-2 Infection Events R-HSA-9772573
Influenza Infection R-HSA-168255
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of RNA R-HSA-8953854
Developmental Biology R-HSA-1266738
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
Interferon Signaling R-HSA-913531
MyD88 cascade initiated on plasma membrane R-HSA-975871
Eukaryotic Translation Elongation R-HSA-156842
Metalloprotease DUBs R-HSA-5689901
Maturation of protein E R-HSA-9683683
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by the B Cell Receptor (BCR) R-HSA-983705
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
rRNA processing in the nucleus and cytosol R-HSA-8868773
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440
DNA Repair R-HSA-73894
Degradation of GLI2 by the proteasome R-HSA-5610783
Protein ubiquitination R-HSA-8852135
Negative regulation of FGFR2 signaling R-HSA-5654727
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Signaling by MET R-HSA-6806834
Mitotic Anaphase R-HSA-68882
Degradation of AXIN R-HSA-4641257
Signaling by NOTCH4 R-HSA-9013694
Regulation of necroptotic cell death R-HSA-5675482
Signaling by PTK6 R-HSA-8848021
Interleukin-1 family signaling R-HSA-446652
Regulation of TP53 Activity through Methylation R-HSA-6804760
Maturation of protein E R-HSA-9694493
VLDLR internalisation and degradation R-HSA-8866427
Disease R-HSA-1643685
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314
IKK complex recruitment mediated by RIP1 R-HSA-937041
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Selective autophagy R-HSA-9663891
FCERI mediated NF-kB activation R-HSA-2871837
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652
Signaling by FGFR3 R-HSA-5654741
Ovarian tumor domain proteases R-HSA-5689896
DNA Replication R-HSA-69306
Termination of translesion DNA synthesis R-HSA-5656169
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313
Regulation of PTEN localization R-HSA-8948747
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Translation initiation complex formation R-HSA-72649
p53-Independent DNA Damage Response R-HSA-69610
UCH proteinases R-HSA-5689603
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Metabolism of amino acids and derivatives R-HSA-71291
Beta-catenin independent WNT signaling R-HSA-3858494
Asymmetric localization of PCP proteins R-HSA-4608870
RAS processing R-HSA-9648002
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional Regulation by TP53 R-HSA-3700989
ER-Phagosome pathway R-HSA-1236974
Glycogen synthesis R-HSA-3322077
Downregulation of ERBB4 signaling R-HSA-1253288
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
ISG15 antiviral mechanism R-HSA-1169408
Nuclear events mediated by NFE2L2 R-HSA-9759194
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of FZD by ubiquitination R-HSA-4641263
Spry regulation of FGF signaling R-HSA-1295596
Regulation of BACH1 activity R-HSA-9708530
Signal Transduction R-HSA-162582
NRIF signals cell death from the nucleus R-HSA-205043
Activation of NF-kappaB in B cells R-HSA-1169091
M Phase R-HSA-68886
Cellular responses to stimuli R-HSA-8953897
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Signaling by ERBB2 R-HSA-1227986
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975
Negative regulation of MAPK pathway R-HSA-5675221
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Eukaryotic Translation Termination R-HSA-72764
Hedgehog 'on' state R-HSA-5632684
G1 Phase R-HSA-69236
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Late endosomal microautophagy R-HSA-9615710
G1/S Transition R-HSA-69206
Pexophagy R-HSA-9664873
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Signaling by CSF3 (G-CSF) R-HSA-9674555
TNF signaling R-HSA-75893
MyD88-independent TLR4 cascade R-HSA-166166
p75NTR signals via NF-kB R-HSA-193639
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Prevention of phagosomal-lysosomal fusion R-HSA-9636383
p75 NTR receptor-mediated signalling R-HSA-193704
Degradation of DVL R-HSA-4641258
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Aggrephagy R-HSA-9646399
rRNA processing R-HSA-72312
Translation of Structural Proteins R-HSA-9694635
Translesion Synthesis by POLH R-HSA-110320
Assembly of the pre-replicative complex R-HSA-68867
Stimuli-sensing channels R-HSA-2672351
DNA Damage Bypass R-HSA-73893
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
ABC transporter disorders R-HSA-5619084
Cytokine Signaling in Immune system R-HSA-1280215
Antigen processing-Cross presentation R-HSA-1236975
Downregulation of ERBB2 signaling R-HSA-8863795
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Cap-dependent Translation Initiation R-HSA-72737
Signaling by ERBB4 R-HSA-1236394
Processing of DNA double-strand break ends R-HSA-5693607
S Phase R-HSA-69242
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Negative regulation of NOTCH4 signaling R-HSA-9604323
DNA Double Strand Break Response R-HSA-5693606
p75NTR recruits signalling complexes R-HSA-209543
Gene expression (Transcription) R-HSA-74160
Degradation of beta-catenin by the destruction complex R-HSA-195253
Dual incision in TC-NER R-HSA-6782135
Nonsense-Mediated Decay (NMD) R-HSA-927802
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Membrane binding and targetting of GAG proteins R-HSA-174490
Oxidative Stress Induced Senescence R-HSA-2559580
Regulation of TP53 Degradation R-HSA-6804757
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
FLT3 signaling in disease R-HSA-9682385
Regulation of RUNX2 expression and activity R-HSA-8939902
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Formation of TC-NER Pre-Incision Complex R-HSA-6781823
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Negative regulation of FGFR4 signaling R-HSA-5654733
ABC-family proteins mediated transport R-HSA-382556
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Selenocysteine synthesis R-HSA-2408557
Cell Cycle Checkpoints R-HSA-69620
Glycogen metabolism R-HSA-8982491
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of NF-kappa B signaling R-HSA-9758274
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic G2-G2/M phases R-HSA-453274
Mitophagy R-HSA-5205647
Translation of Structural Proteins R-HSA-9683701
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Interleukin-17 signaling R-HSA-448424
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
G2/M Transition R-HSA-69275
Downregulation of TGF-beta receptor signaling R-HSA-2173788
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Host Interactions of HIV factors R-HSA-162909
Regulated Necrosis R-HSA-5218859
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK family signaling cascades R-HSA-5683057
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
MAP kinase activation R-HSA-450294
Budding and maturation of HIV virion R-HSA-162588
Glycogen storage diseases R-HSA-3229121
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Mitotic G1 phase and G1/S transition R-HSA-453279
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Signaling by NOTCH2 R-HSA-1980145
TCR signaling R-HSA-202403
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Membrane Trafficking R-HSA-199991
DNA Double-Strand Break Repair R-HSA-5693532
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
SARS-CoV Infections R-HSA-9679506
Cell Cycle, Mitotic R-HSA-69278
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
HIV Infection R-HSA-162906
Cellular Senescence R-HSA-2559583
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Suppression of phagosomal maturation R-HSA-9637687
Signaling by CSF3 (G-CSF) R-HSA-9674555
Axon guidance R-HSA-422475
Maturation of protein E R-HSA-9683683
NOD1/2 Signaling Pathway R-HSA-168638
Translation initiation complex formation R-HSA-72649
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Signaling by NOTCH3 R-HSA-9012852
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110
FCERI mediated NF-kB activation R-HSA-2871837
Membrane binding and targetting of GAG proteins R-HSA-174490
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973
Metalloprotease DUBs R-HSA-5689901
Signaling by FGFR3 R-HSA-5654741
Nervous system development R-HSA-9675108
FLT3 signaling by CBL mutants R-HSA-9706377
ISG15 antiviral mechanism R-HSA-1169408
MAPK6/MAPK4 signaling R-HSA-5687128
TCF dependent signaling in response to WNT R-HSA-201681
Selenoamino acid metabolism R-HSA-2408522
S Phase R-HSA-69242
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827
Iron uptake and transport R-HSA-917937
Response of Mtb to phagocytosis R-HSA-9637690
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Glycogen metabolism R-HSA-8982491
Switching of origins to a post-replicative state R-HSA-69052
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Translation of Structural Proteins R-HSA-9694635
rRNA processing in the nucleus and cytosol R-HSA-8868773
MAPK family signaling cascades R-HSA-5683057
Regulation of Apoptosis R-HSA-169911
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314
SARS-CoV-2-host interactions R-HSA-9705683
CLEC7A (Dectin-1) signaling R-HSA-5607764
Diseases of carbohydrate metabolism R-HSA-5663084
Cell Cycle R-HSA-1640170
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Selective autophagy R-HSA-9663891
EGFR downregulation R-HSA-182971
Signaling by MET R-HSA-6806834
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325
Synthesis of DNA R-HSA-69239
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MyD88 cascade initiated on plasma membrane R-HSA-975871
Downregulation of ERBB4 signaling R-HSA-1253288
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Death Receptor Signaling R-HSA-73887
Separation of Sister Chromatids R-HSA-2467813
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Listeria monocytogenes entry into host cells R-HSA-8876384
Oxidative Stress Induced Senescence R-HSA-2559580
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Cellular responses to stress R-HSA-2262752
Negative regulation of MET activity R-HSA-6807004
DNA Repair R-HSA-73894
HDR through Homologous Recombination (HRR) R-HSA-5685942
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
ABC-family proteins mediated transport R-HSA-382556
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Eukaryotic Translation Elongation R-HSA-156842
Adaptive Immune System R-HSA-1280218
Degradation of beta-catenin by the destruction complex R-HSA-195253
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210
Selenocysteine synthesis R-HSA-2408557
Hedgehog 'on' state R-HSA-5632684
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695
Signaling by EGFR R-HSA-177929
Signaling by ERBB2 R-HSA-1227986
Regulation of PTEN localization R-HSA-8948747
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Stimuli-sensing channels R-HSA-2672351
MyD88-independent TLR4 cascade R-HSA-166166
Nucleotide Excision Repair R-HSA-5696398
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity R-HSA-5633007
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Prevention of phagosomal-lysosomal fusion R-HSA-9636383
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Circadian Clock R-HSA-400253
Aggrephagy R-HSA-9646399
PIP3 activates AKT signaling R-HSA-1257604
RIPK1-mediated regulated necrosis R-HSA-5213460
Glycogen storage diseases R-HSA-3229121
DNA Damage Bypass R-HSA-73893
Late Phase of HIV Life Cycle R-HSA-162599
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Eukaryotic Translation Termination R-HSA-72764
Ub-specific processing proteases R-HSA-5689880
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Eukaryotic Translation Initiation R-HSA-72613
Stabilization of p53 R-HSA-69541
Hedgehog 'off' state R-HSA-5610787
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956
G2/M Checkpoints R-HSA-69481
G1 Phase R-HSA-69236
Macroautophagy R-HSA-1632852
Translesion synthesis by POLK R-HSA-5655862
Asymmetric localization of PCP proteins R-HSA-4608870
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012
G1/S Transition R-HSA-69206
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Intracellular signaling by second messengers R-HSA-9006925
Asparagine N-linked glycosylation R-HSA-446203
Innate Immune System R-HSA-168249
Cellular response to chemical stress R-HSA-9711123
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Cyclin D associated events in G1 R-HSA-69231
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440
IRAK1 recruits IKK complex R-HSA-937039
Degradation of AXIN R-HSA-4641257
NF-kB is activated and signals survival R-HSA-209560
Metabolism R-HSA-1430728
Late endosomal microautophagy R-HSA-9615710
DNA Replication R-HSA-69306
Downstream TCR signaling R-HSA-202424
M Phase R-HSA-68886
Generic Transcription Pathway R-HSA-212436
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Peptide chain elongation R-HSA-156902
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Signaling by ERBB4 R-HSA-1236394
Termination of translesion DNA synthesis R-HSA-5656169
Protein localization R-HSA-9609507
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729
Ribosomal scanning and start codon recognition R-HSA-72702
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Metabolism of carbohydrates R-HSA-71387
Transcriptional regulation by RUNX3 R-HSA-8878159
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by NOTCH4 R-HSA-9013694
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Negative regulation of FGFR1 signaling R-HSA-5654726
Glycogen synthesis R-HSA-3322077
Ion channel transport R-HSA-983712
UCH proteinases R-HSA-5689603
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Budding and maturation of HIV virion R-HSA-162588
Dual incision in TC-NER R-HSA-6782135
Assembly Of The HIV Virion R-HSA-175474
MyD88 dependent cascade initiated on endosome R-HSA-975155
Mitophagy R-HSA-5205647
Antigen processing-Cross presentation R-HSA-1236975
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Regulation of RAS by GAPs R-HSA-5658442
Spry regulation of FGF signaling R-HSA-1295596
Translesion synthesis by REV1 R-HSA-110312
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autophagy R-HSA-9612973
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transport of small molecules R-HSA-382551
SARS-CoV-2 modulates host translation machinery R-HSA-9754678
Translation of Structural Proteins R-HSA-9683701
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493
Regulation of BACH1 activity R-HSA-9708530
TNF signaling R-HSA-75893
ER Quality Control Compartment (ERQC) R-HSA-901032
Alpha-protein kinase 1 signaling pathway R-HSA-9645460
Diseases of metabolism R-HSA-5668914
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of RNA R-HSA-8953854
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Vesicle-mediated transport R-HSA-5653656
Apoptosis R-HSA-109581
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Translesion synthesis by POLI R-HSA-5656121
Signaling by PTK6 R-HSA-8848021
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975
TCR signaling R-HSA-202403
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Cytokine Signaling in Immune system R-HSA-1280215
VLDLR internalisation and degradation R-HSA-8866427
DNA Replication Pre-Initiation R-HSA-69002
Regulation of PTEN stability and activity R-HSA-8948751
Orc1 removal from chromatin R-HSA-68949
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Negative regulation of FGFR2 signaling R-HSA-5654727
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
SARS-CoV-1-host interactions R-HSA-9692914
PTEN Regulation R-HSA-6807070
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Disorders of transmembrane transporters R-HSA-5619115
Signaling by FGFR1 R-HSA-5654736
Signal Transduction R-HSA-162582
Mitotic Anaphase R-HSA-68882
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Late SARS-CoV-2 Infection Events R-HSA-9772573
HIV Life Cycle R-HSA-162587
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Independent DNA Damage Response R-HSA-69610
SARS-CoV-1 modulates host translation machinery R-HSA-9735869
Clathrin-mediated endocytosis R-HSA-8856828
Plasma lipoprotein clearance R-HSA-8964043
Neddylation R-HSA-8951664
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706
Vif-mediated degradation of APOBEC3G R-HSA-180585
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
RNA Polymerase II Transcription R-HSA-73857
Formation of Incision Complex in GG-NER R-HSA-5696395
Transcriptional regulation by RUNX1 R-HSA-8878171
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Modulation by Mtb of host immune system R-HSA-9637628
Regulation of FZD by ubiquitination R-HSA-4641263
Calnexin/calreticulin cycle R-HSA-901042
Regulation of NF-kappa B signaling R-HSA-9758274
Metabolism of proteins R-HSA-392499
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by Interleukins R-HSA-449147
Vpu mediated degradation of CD4 R-HSA-180534
Formation of a pool of free 40S subunits R-HSA-72689
Interleukin-1 family signaling R-HSA-446652
DNA Double Strand Break Response R-HSA-5693606
Assembly of the pre-replicative complex R-HSA-68867
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by FGFR2 R-HSA-5654738
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Mitotic Metaphase and Anaphase R-HSA-2555396
Pexophagy R-HSA-9664873
Activation of NF-kappaB in B cells R-HSA-1169091
Dual Incision in GG-NER R-HSA-5696400
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957
Regulation of TNFR1 signaling R-HSA-5357905
SARS-CoV-2 Infection R-HSA-9694516
Interleukin-1 signaling R-HSA-9020702
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Host Interactions of HIV factors R-HSA-162909
Transcriptional Regulation by TP53 R-HSA-3700989
p75 NTR receptor-mediated signalling R-HSA-193704
Homology Directed Repair R-HSA-5693538
Protein ubiquitination R-HSA-8852135
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Interleukin-17 signaling R-HSA-448424
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
NRIF signals cell death from the nucleus R-HSA-205043
FLT3 signaling in disease R-HSA-9682385
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397
Downregulation of TGF-beta receptor signaling R-HSA-2173788
Regulation of necroptotic cell death R-HSA-5675482
Regulation of TP53 Activity through Methylation R-HSA-6804760
Cap-dependent Translation Initiation R-HSA-72737
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
Regulation of RUNX3 expression and activity R-HSA-8941858
Developmental Biology R-HSA-1266738
Signaling by TGF-beta Receptor Complex R-HSA-170834
Defective CFTR causes cystic fibrosis R-HSA-5678895
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hh mutants are degraded by ERAD R-HSA-5362768
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Signaling by NOTCH2 R-HSA-1980145
Amyloid fiber formation R-HSA-977225
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by WNT R-HSA-195721
Infectious disease R-HSA-5663205
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
DNA Damage Recognition in GG-NER R-HSA-5696394
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
Cellular response to starvation R-HSA-9711097
IKK complex recruitment mediated by RIP1 R-HSA-937041
Influenza Viral RNA Transcription and Replication R-HSA-168273
Regulated Necrosis R-HSA-5218859
ABC transporter disorders R-HSA-5619084
Deubiquitination R-HSA-5688426
Viral mRNA Translation R-HSA-192823
Nonsense-Mediated Decay (NMD) R-HSA-927802
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
IRAK2 mediated activation of TAK1 complex R-HSA-937042
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Chaperone Mediated Autophagy R-HSA-9613829
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Maturation of protein E R-HSA-9694493
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Nuclear events mediated by NFE2L2 R-HSA-9759194
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Negative regulation of FGFR3 signaling R-HSA-5654732
Cyclin E associated events during G1/S transition R-HSA-69202
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Regulation of TP53 Expression and Degradation R-HSA-6806003
FLT3 Signaling R-HSA-9607240
Ovarian tumor domain proteases R-HSA-5689896
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stimuli R-HSA-8953897
Downregulation of ERBB2 signaling R-HSA-8863795
Oncogene Induced Senescence R-HSA-2559585
p75NTR signals via NF-kB R-HSA-193639
Signaling by TGFB family members R-HSA-9006936
Hedgehog ligand biogenesis R-HSA-5358346
Cellular response to hypoxia R-HSA-1234174
Processing of DNA double-strand break ends R-HSA-5693607
Mitotic G2-G2/M phases R-HSA-453274
MAP kinase activation R-HSA-450294
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232
Toll-like Receptor Cascades R-HSA-168898
RAS processing R-HSA-9648002
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
G2/M Transition R-HSA-69275
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Regulation of TP53 Degradation R-HSA-6804757
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hh mutants abrogate ligand secretion R-HSA-5387390
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by FGFR R-HSA-190236
Regulation of mitotic cell cycle R-HSA-453276
Negative regulation of FLT3 R-HSA-9706369
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Formation of TC-NER Pre-Incision Complex R-HSA-6781823
Signaling by EGFR in Cancer R-HSA-1643713
Influenza Infection R-HSA-168255
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Peroxisomal protein import R-HSA-9033241
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
ER-Phagosome pathway R-HSA-1236974
Translesion Synthesis by POLH R-HSA-110320
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of amino acids and derivatives R-HSA-71291
Interferon Signaling R-HSA-913531
Regulation of signaling by CBL R-HSA-912631
Class I MHC mediated antigen processing & presentation R-HSA-983169
Fanconi Anemia Pathway R-HSA-6783310
RAF/MAP kinase cascade R-HSA-5673001
Programmed Cell Death R-HSA-5357801
PINK1-PRKN Mediated Mitophagy R-HSA-5205685
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Degradation of DVL R-HSA-4641258
Signaling by FGFR4 R-HSA-5654743
C-type lectin receptors (CLRs) R-HSA-5621481
Translation R-HSA-72766
Negative regulation of FGFR4 signaling R-HSA-5654733
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
Disease R-HSA-1643685
Signaling by ROBO receptors R-HSA-376176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Immune System R-HSA-168256
p75NTR recruits signalling complexes R-HSA-209543
Signaling by NOTCH1 R-HSA-1980143
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK1/MAPK3 signaling R-HSA-5684996
SARS-CoV-1 Infection R-HSA-9678108
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Myoclonic epilepsy of Lafora R-HSA-3785653
Josephin domain DUBs R-HSA-5689877
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Negative regulation of MAPK pathway R-HSA-5675221
rRNA processing R-HSA-72312
Signaling by Hedgehog R-HSA-5358351
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by NOTCH R-HSA-157118

Expression Atlas ENSG00000143947
NCBI gene (formerly Entrezgene) 6233
GeneCards 10417
HGNC Symbol HGNC:10417
MIM gene 191343
UniProtKB Gene Name P62979
WikiGene 6233