Ensembl ID :
ENSG00000100823
Description: apurinic/apyrimidinic endodeoxyribonuclease 1
Gene Synonyms: APE,APE-1,APEN,APEX,APX,HAP1,REF-1,REF1
1 APIs:
214 Possible Orthologues:
DNA Repair
R-HSA-73894
PCNA-Dependent Long Patch Base Excision Repair
R-HSA-5651801
Resolution of AP sites via the single-nucleotide replacement pathway
R-HSA-110381
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
R-HSA-73930
Resolution of AP sites via the multiple-nucleotide patch replacement pathway
R-HSA-110373
Displacement of DNA glycosylase by APEX1
R-HSA-110357
POLB-Dependent Long Patch Base Excision Repair
R-HSA-110362
Resolution of Abasic Sites (AP sites)
R-HSA-73933
Base Excision Repair
R-HSA-73884
Resolution of AP sites via the multiple-nucleotide patch replacement pathway
R-HSA-110373
POLB-Dependent Long Patch Base Excision Repair
R-HSA-110362
PCNA-Dependent Long Patch Base Excision Repair
R-HSA-5651801
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
R-HSA-73930
Resolution of Abasic Sites (AP sites)
R-HSA-73933
Resolution of AP sites via the single-nucleotide replacement pathway
R-HSA-110381
Displacement of DNA glycosylase by APEX1
R-HSA-110357
Base Excision Repair
R-HSA-73884
DNA Repair
R-HSA-73894
PCNA-Dependent Long Patch Base Excision Repair
R-HSA-5651801
DNA Repair
R-HSA-73894
Resolution of AP sites via the multiple-nucleotide patch replacement pathway
R-HSA-110373
Resolution of AP sites via the single-nucleotide replacement pathway
R-HSA-110381
Resolution of Abasic Sites (AP sites)
R-HSA-73933
POLB-Dependent Long Patch Base Excision Repair
R-HSA-110362
Base Excision Repair
R-HSA-73884
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
R-HSA-73930
Displacement of DNA glycosylase by APEX1
R-HSA-110357
POLB-Dependent Long Patch Base Excision Repair
R-HSA-110362
DNA Repair
R-HSA-73894
Resolution of AP sites via the multiple-nucleotide patch replacement pathway
R-HSA-110373
Base Excision Repair
R-HSA-73884
Displacement of DNA glycosylase by APEX1
R-HSA-110357
Resolution of AP sites via the single-nucleotide replacement pathway
R-HSA-110381
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
R-HSA-73930
PCNA-Dependent Long Patch Base Excision Repair
R-HSA-5651801
Resolution of Abasic Sites (AP sites)
R-HSA-73933
Resolution of Abasic Sites (AP sites)
R-HSA-73933
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
R-HSA-73930
Resolution of AP sites via the multiple-nucleotide patch replacement pathway
R-HSA-110373
Base Excision Repair
R-HSA-73884
PCNA-Dependent Long Patch Base Excision Repair
R-HSA-5651801
Resolution of AP sites via the single-nucleotide replacement pathway
R-HSA-110381
DNA Repair
R-HSA-73894
POLB-Dependent Long Patch Base Excision Repair
R-HSA-110362
Displacement of DNA glycosylase by APEX1
R-HSA-110357
DNA Repair
R-HSA-73894
POLB-Dependent Long Patch Base Excision Repair
R-HSA-110362
Base Excision Repair
R-HSA-73884
PCNA-Dependent Long Patch Base Excision Repair
R-HSA-5651801
Displacement of DNA glycosylase by APEX1
R-HSA-110357
Resolution of AP sites via the single-nucleotide replacement pathway
R-HSA-110381
Resolution of Abasic Sites (AP sites)
R-HSA-73933
Resolution of AP sites via the multiple-nucleotide patch replacement pathway
R-HSA-110373
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
R-HSA-73930
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
R-HSA-73930
Displacement of DNA glycosylase by APEX1
R-HSA-110357
Resolution of AP sites via the single-nucleotide replacement pathway
R-HSA-110381
Resolution of AP sites via the multiple-nucleotide patch replacement pathway
R-HSA-110373
PCNA-Dependent Long Patch Base Excision Repair
R-HSA-5651801
DNA Repair
R-HSA-73894
POLB-Dependent Long Patch Base Excision Repair
R-HSA-110362
Resolution of Abasic Sites (AP sites)
R-HSA-73933
Base Excision Repair
R-HSA-73884
Base Excision Repair
R-HSA-73884
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
R-HSA-73930
DNA Repair
R-HSA-73894
Resolution of AP sites via the single-nucleotide replacement pathway
R-HSA-110381
Resolution of AP sites via the multiple-nucleotide patch replacement pathway
R-HSA-110373
Displacement of DNA glycosylase by APEX1
R-HSA-110357
Resolution of Abasic Sites (AP sites)
R-HSA-73933
PCNA-Dependent Long Patch Base Excision Repair
R-HSA-5651801
POLB-Dependent Long Patch Base Excision Repair
R-HSA-110362
Base Excision Repair
R-HSA-73884
DNA Repair
R-HSA-73894
POLB-Dependent Long Patch Base Excision Repair
R-HSA-110362
Resolution of AP sites via the multiple-nucleotide patch replacement pathway
R-HSA-110373
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
R-HSA-73930
PCNA-Dependent Long Patch Base Excision Repair
R-HSA-5651801
Resolution of Abasic Sites (AP sites)
R-HSA-73933
Displacement of DNA glycosylase by APEX1
R-HSA-110357
Resolution of AP sites via the single-nucleotide replacement pathway
R-HSA-110381
DNA Repair
R-HSA-73894
Displacement of DNA glycosylase by APEX1
R-HSA-110357
PCNA-Dependent Long Patch Base Excision Repair
R-HSA-5651801
Resolution of AP sites via the single-nucleotide replacement pathway
R-HSA-110381
POLB-Dependent Long Patch Base Excision Repair
R-HSA-110362
Base Excision Repair
R-HSA-73884
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
R-HSA-73930
Resolution of AP sites via the multiple-nucleotide patch replacement pathway
R-HSA-110373
Resolution of Abasic Sites (AP sites)
R-HSA-73933
DNA Repair
R-HSA-73894
Resolution of Abasic Sites (AP sites)
R-HSA-73933
Base Excision Repair
R-HSA-73884
PCNA-Dependent Long Patch Base Excision Repair
R-HSA-5651801
Displacement of DNA glycosylase by APEX1
R-HSA-110357
Resolution of AP sites via the single-nucleotide replacement pathway
R-HSA-110381
Resolution of AP sites via the multiple-nucleotide patch replacement pathway
R-HSA-110373
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
R-HSA-73930
POLB-Dependent Long Patch Base Excision Repair
R-HSA-110362
Ensembl ID :
ENSG00000149806
Description: FAU ubiquitin like and ribosomal protein S30 fusion
Gene Synonyms: ASR1,FLJ22986,FUB1,FUBI,MNSFBETA,RPS30,S30
4 APIs:
246 Possible Orthologues:
Ensembl ID :
ENSG00000080824
Description: heat shock protein 90 alpha family class A member 1
Gene Synonyms: FLJ31884,HSP89,HSP90,HSP90N,HSPC1,HSPCA
9 APIs:
263 Possible Orthologues:
Fergal J Martin, M Ridwan Amode, Alisha Aneja, Olanrewaju Austine-Orimoloye, Andrey G Azov,
If Barnes, Arne Becker, Ruth Bennett, Andrew Berry, Jyothish Bhai, Simarpreet Kaur Bhurji,
Alexandra Bignell, Sanjay Boddu, Paulo R Branco Lins, Lucy Brooks, Shashank Budhanuru Ramaraju,
Mehrnaz Charkhchi, Alexander Cockburn, Luca Da Rin Fiorretto, Claire Davidson, Kamalkumar Dodiya,
Sarah Donaldson, Bilal El Houdaigui, Tamara El Naboulsi, Reham Fatima, Carlos Garcia Giron,
Thiago Genez, Gurpreet S Ghattaoraya, Jose Gonzalez Martinez, Cristi Guijarro, Matthew Hardy,
Zoe Hollis, Thibaut Hourlier, Toby Hunt, Mike Kay, Vinay Kaykala, Tuan Le, Diana Lemos,
Diego Marques-Coelho, José Carlos Marugán, Gabriela Alejandra Merino, Louisse Paola Mirabueno,
Aleena Mushtaq, Syed Nakib Hossain, Denye N Ogeh, Manoj Pandian Sakthivel, Anne Parker, Malcolm Perry,
Ivana Piližota, Irina Prosovetskaia, José G Pérez-Silva, Ahamed Imran Abdul Salam, Nuno Saraiva-Agostinho,
Helen Schuilenburg, Dan Sheppard, Swati Sinha, Botond Sipos, William Stark, Emily Steed, Ranjit Sukumaran,
Dulika Sumathipala, Marie-Marthe Suner, Likhitha Surapaneni, Kyösti Sutinen, Michal Szpak,
Francesca Floriana Tricomi, David Urbina-Gómez, Andres Veidenberg, Thomas A Walsh,
Brandon Walts, Elizabeth Wass, Natalie Willhoft, Jamie Allen, Jorge Alvarez-Jarreta,
Marc Chakiachvili, Bethany Flint, Stefano Giorgetti, Leanne Haggerty, Garth R Ilsley,
Jane E Loveland, Benjamin Moore, Jonathan M Mudge, John Tate, David Thybert,
Stephen J Trevanion, Andrea Winterbottom, Adam Frankish, Sarah E Hunt, Magali Ruffier,
Fiona Cunningham, Sarah Dyer, Robert D Finn, Kevin L Howe, Peter W Harrison, Andrew D Yates,
Paul Flicek, Ensembl 2023, Nucleic Acids Research, Volume 51, Issue D1, 6 January 2023,
Pages D933–D941, Read...
2. ChEMBL:
Barbara Zdrazil, Eloy Felix, Fiona Hunter, Emma J Manners, James Blackshaw, Sybilla Corbett,
Marleen de Veij, Harris Ioannidis, David Mendez Lopez, Juan F Mosquera, Maria Paula Magarinos,
Nicolas Bosc, Ricardo Arcila, Tevfik Kizilören, Anna Gaulton, A Patrícia Bento,
Melissa F Adasme, Peter Monecke, Gregory A Landrum, Andrew R Leach,
The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods,
Nucleic Acids Research, Volume 52, Issue D1, 5 January 2024, Pages D1180–D1192,
Read...
3. UniProt:
Elisabeth Coudert, Sebastien Gehant, Edouard de Castro, Monica Pozzato, Delphine Baratin,
Teresa Neto, Christian J A Sigrist, Nicole Redaschi, Alan Bridge, The UniProt Consortium ,
Annotation of biologically relevant ligands in UniProtKB using ChEBI,
Bioinformatics, Volume 39, Issue 1, January 2023, btac793,
Read...
4. IUPHAR/BPS guide to pharmacology:
Simon D Harding, Jane F Armstrong, Elena Faccenda, Christopher Southan, Stephen P H Alexander,
Anthony P Davenport, Michael Spedding, Jamie A Davies, The IUPHAR/BPS Guide to PHARMACOLOGY in 2024,
Nucleic Acids Research, Volume 52, Issue D1, 5 January 2024, Pages D1438–D1449,
Read...
5. IUPHAR/BPS guide to pharmacology:
Simon D Harding, Jane F Armstrong, Elena Faccenda, Christopher Southan, Stephen P H Alexander,
Anthony P Davenport, Michael Spedding, Jamie A Davies, The IUPHAR/BPS Guide to PHARMACOLOGY in 2024,
Nucleic Acids Research, Volume 52, Issue D1, 5 January 2024, Pages D1438–D1449,
Read...
6. Reactome:
Marija Milacic, Deidre Beavers, Patrick Conley, Chuqiao Gong, Marc Gillespie, Johannes Griss,
Robin Haw, Bijay Jassal, Lisa Matthews, Bruce May, Robert Petryszak, Eliot Ragueneau,
Karen Rothfels, Cristoffer Sevilla, Veronica Shamovsky, Ralf Stephan, Krishna Tiwari,
Thawfeek Varusai, Joel Weiser, Adam Wright, Guanming Wu, Lincoln Stein, Henning Hermjakob,
Peter D’Eustachio, The Reactome Pathway Knowledgebase 2024, Nucleic Acids Research,
Volume 52, Issue D1, 5 January 2024, Pages D672–D678,
Read...
7. HUGO Gene Nomenclature Committee:
Ruth L Seal, Bryony Braschi, Kristian Gray, Tamsin E M Jones, Susan Tweedie, Liora Haim-Vilmovsky,
Elspeth A Bruford, Genenames.org: the HGNC resources in 2023, Nucleic Acids Research,
Volume 51, Issue D1, 6 January 2023, Pages D1003–D1009,
Read...
8. NORMAN SUSDAT
NORMAN Network, Aalizadeh, R., Alygizakis, N., Schymanski, E., Slobodnik, J., Fischer, S.,
Cirka, L., & Mohammed Taha, H. (2024). S0 | SUSDAT | Merged NORMAN Suspect List:
SusDat (NORMAN-SLE-S0.0.5.1) [Data set]. Zenodo.
Read...