Gene: PSMA8
Ensembl ID : ENSG00000154611
Description: proteasome 20S subunit alpha 8
Gene Synonyms: MGC26605,PSMA7L
6 APIs:
197 Possible Orthologues:

S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by WNT R-HSA-195721
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
TCF dependent signaling in response to WNT R-HSA-201681
Synthesis of DNA R-HSA-69239
NIK-->noncanonical NF-kB signaling R-HSA-5676590
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
FCERI mediated NF-kB activation R-HSA-2871837
Cellular response to hypoxia R-HSA-1234174
Regulation of RAS by GAPs R-HSA-5658442
Innate Immune System R-HSA-168249
Metabolism of amino acids and derivatives R-HSA-71291
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of DVL R-HSA-4641258
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Antigen processing-Cross presentation R-HSA-1236975
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
CLEC7A (Dectin-1) signaling R-HSA-5607764
UCH proteinases R-HSA-5689603
DNA Replication R-HSA-69306
Deubiquitination R-HSA-5688426
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic Anaphase R-HSA-68882
Apoptosis R-HSA-109581
Metabolism of RNA R-HSA-8953854
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
ABC-family proteins mediated transport R-HSA-382556
Cytokine Signaling in Immune system R-HSA-1280215
Transport of small molecules R-HSA-382551
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Separation of Sister Chromatids R-HSA-2467813
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Post-translational protein modification R-HSA-597592
Degradation of GLI2 by the proteasome R-HSA-5610783
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of polyamines R-HSA-351202
ABC transporter disorders R-HSA-5619084
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK family signaling cascades R-HSA-5683057
Hh mutants abrogate ligand secretion R-HSA-5387390
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
G2/M Transition R-HSA-69275
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
Hedgehog ligand biogenesis R-HSA-5358346
Activation of NF-kappaB in B cells R-HSA-1169091
Developmental Biology R-HSA-1266738
Neddylation R-HSA-8951664
Infectious disease R-HSA-5663205
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RUNX2 expression and activity R-HSA-8939902
Defective CFTR causes cystic fibrosis R-HSA-5678895
Axon guidance R-HSA-422475
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Hedgehog 'off' state R-HSA-5610787
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Asymmetric localization of PCP proteins R-HSA-4608870
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
Orc1 removal from chromatin R-HSA-68949
Host Interactions of HIV factors R-HSA-162909
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent DNA Damage Response R-HSA-69610
Immune System R-HSA-168256
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Signaling by ROBO receptors R-HSA-376176
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX2 R-HSA-8878166
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by Hedgehog R-HSA-5358351
G2/M Checkpoints R-HSA-69481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of Apoptosis R-HSA-169911
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Interleukins R-HSA-449147
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
Stabilization of p53 R-HSA-69541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
M Phase R-HSA-68886
G1/S DNA Damage Checkpoints R-HSA-69615
Hedgehog 'on' state R-HSA-5632684
Cellular response to chemical stress R-HSA-9711123
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
PTEN Regulation R-HSA-6807070
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX1 R-HSA-8878171
PIP3 activates AKT signaling R-HSA-1257604
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ub-specific processing proteases R-HSA-5689880
Infectious disease R-HSA-5663205
Downstream TCR signaling R-HSA-202424
Ub-specific processing proteases R-HSA-5689880
Signaling by ROBO receptors R-HSA-376176
Disease R-HSA-1643685
Metabolism of polyamines R-HSA-351202
Nervous system development R-HSA-9675108
Antigen processing-Cross presentation R-HSA-1236975
Synthesis of DNA R-HSA-69239
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stress R-HSA-2262752
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
PCP/CE pathway R-HSA-4086400
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by Interleukins R-HSA-449147
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RAS by GAPs R-HSA-5658442
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Deubiquitination R-HSA-5688426
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Host Interactions of HIV factors R-HSA-162909
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic Metaphase and Anaphase R-HSA-2555396
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
M Phase R-HSA-68886
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G2/M Checkpoints R-HSA-69481
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic G2-G2/M phases R-HSA-453274
Innate Immune System R-HSA-168249
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by WNT R-HSA-195721
Cell Cycle R-HSA-1640170
Programmed Cell Death R-HSA-5357801
MAPK family signaling cascades R-HSA-5683057
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ABC transporter disorders R-HSA-5619084
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
Interleukin-1 signaling R-HSA-9020702
Regulation of mitotic cell cycle R-HSA-453276
Cellular response to chemical stress R-HSA-9711123
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular response to hypoxia R-HSA-1234174
G2/M Transition R-HSA-69275
RAF/MAP kinase cascade R-HSA-5673001
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism R-HSA-1430728
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
DNA Replication R-HSA-69306
ABC-family proteins mediated transport R-HSA-382556
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants abrogate ligand secretion R-HSA-5387390
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Stabilization of p53 R-HSA-69541
Degradation of AXIN R-HSA-4641257
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Hedgehog R-HSA-5358351
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX1 R-HSA-8878171
Apoptosis R-HSA-109581
Degradation of beta-catenin by the destruction complex R-HSA-195253
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
ER-Phagosome pathway R-HSA-1236974
CLEC7A (Dectin-1) signaling R-HSA-5607764
RNA Polymerase II Transcription R-HSA-73857
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1 DNA Damage Response R-HSA-69563
PTEN Regulation R-HSA-6807070
Regulation of PTEN stability and activity R-HSA-8948751
Developmental Biology R-HSA-1266738
Hedgehog 'off' state R-HSA-5610787
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TCF dependent signaling in response to WNT R-HSA-201681
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK6/MAPK4 signaling R-HSA-5687128
HIV Infection R-HSA-162906
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
Intracellular signaling by second messengers R-HSA-9006925
Degradation of DVL R-HSA-4641258
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of Apoptosis R-HSA-169911
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transport of small molecules R-HSA-382551
Hedgehog 'on' state R-HSA-5632684
Hedgehog ligand biogenesis R-HSA-5358346
Generic Transcription Pathway R-HSA-212436
Degradation of GLI2 by the proteasome R-HSA-5610783
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Axon guidance R-HSA-422475
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Mitotic Anaphase R-HSA-68882
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PCP/CE pathway R-HSA-4086400
Activation of NF-kappaB in B cells R-HSA-1169091
Asymmetric localization of PCP proteins R-HSA-4608870
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Disorders of transmembrane transporters R-HSA-5619115
Host Interactions of HIV factors R-HSA-162909
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX2 R-HSA-8878166
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by WNT R-HSA-195721
Post-translational protein modification R-HSA-597592
C-type lectin receptors (CLRs) R-HSA-5621481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'off' state R-HSA-5610787
Metabolism of proteins R-HSA-392499
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by ROBO receptors R-HSA-376176
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX1 R-HSA-8878171
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Dependent G1 DNA Damage Response R-HSA-69563
G2/M Checkpoints R-HSA-69481
HIV Infection R-HSA-162906
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of AXIN R-HSA-4641257
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
Cellular responses to stress R-HSA-2262752
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants abrogate ligand secretion R-HSA-5387390
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
Metabolism of polyamines R-HSA-351202
PTEN Regulation R-HSA-6807070
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Deubiquitination R-HSA-5688426
MAPK1/MAPK3 signaling R-HSA-5684996
Vif-mediated degradation of APOBEC3G R-HSA-180585
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic Anaphase R-HSA-68882
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
Disease R-HSA-1643685
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Programmed Cell Death R-HSA-5357801
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX2 expression and activity R-HSA-8939902
Neddylation R-HSA-8951664
Downstream TCR signaling R-HSA-202424
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
M Phase R-HSA-68886
Interleukin-1 signaling R-HSA-9020702
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
Infectious disease R-HSA-5663205
Separation of Sister Chromatids R-HSA-2467813
Signaling by Hedgehog R-HSA-5358351
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle R-HSA-1640170
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication R-HSA-69306
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to hypoxia R-HSA-1234174
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of Apoptosis R-HSA-169911
Regulation of mitotic cell cycle R-HSA-453276
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Intracellular signaling by second messengers R-HSA-9006925
G2/M Transition R-HSA-69275
Regulation of PTEN stability and activity R-HSA-8948751
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RAS by GAPs R-HSA-5658442
PIP3 activates AKT signaling R-HSA-1257604
Degradation of beta-catenin by the destruction complex R-HSA-195253
ABC-family proteins mediated transport R-HSA-382556
Hedgehog ligand biogenesis R-HSA-5358346
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
UCH proteinases R-HSA-5689603
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Stabilization of p53 R-HSA-69541
G1/S DNA Damage Checkpoints R-HSA-69615
Nervous system development R-HSA-9675108
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'on' state R-HSA-5632684
Developmental Biology R-HSA-1266738
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Axon guidance R-HSA-422475
Switching of origins to a post-replicative state R-HSA-69052
Signal Transduction R-HSA-162582
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ub-specific processing proteases R-HSA-5689880
ER-Phagosome pathway R-HSA-1236974
Cell Cycle Checkpoints R-HSA-69620
Vpu mediated degradation of CD4 R-HSA-180534
RAF/MAP kinase cascade R-HSA-5673001
TCR signaling R-HSA-202403
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 family signaling R-HSA-446652
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PCP/CE pathway R-HSA-4086400
G1/S DNA Damage Checkpoints R-HSA-69615
Orc1 removal from chromatin R-HSA-68949
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCF dependent signaling in response to WNT R-HSA-201681
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
ER-Phagosome pathway R-HSA-1236974
Adaptive Immune System R-HSA-1280218
Antigen processing-Cross presentation R-HSA-1236975
Beta-catenin independent WNT signaling R-HSA-3858494
Vif-mediated degradation of APOBEC3G R-HSA-180585
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 family signaling R-HSA-446652
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Independent DNA Damage Response R-HSA-69610
RAF/MAP kinase cascade R-HSA-5673001
Regulation of RAS by GAPs R-HSA-5658442
Apoptosis R-HSA-109581
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
MAPK family signaling cascades R-HSA-5683057
CLEC7A (Dectin-1) signaling R-HSA-5607764
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'off' state R-HSA-5610787
S Phase R-HSA-69242
Axon guidance R-HSA-422475
Cell Cycle R-HSA-1640170
MAPK1/MAPK3 signaling R-HSA-5684996
ABC transporter disorders R-HSA-5619084
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to chemical stress R-HSA-9711123
Metabolism of polyamines R-HSA-351202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK6/MAPK4 signaling R-HSA-5687128
Deubiquitination R-HSA-5688426
Hh mutants are degraded by ERAD R-HSA-5362768
G2/M Checkpoints R-HSA-69481
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by WNT R-HSA-195721
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ub-specific processing proteases R-HSA-5689880
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signal Transduction R-HSA-162582
Downstream TCR signaling R-HSA-202424
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
Degradation of AXIN R-HSA-4641257
Nervous system development R-HSA-9675108
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TCR signaling R-HSA-202403
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
Transport of small molecules R-HSA-382551
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular responses to stimuli R-HSA-8953897
HIV Infection R-HSA-162906
G2/M Transition R-HSA-69275
ABC-family proteins mediated transport R-HSA-382556
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Innate Immune System R-HSA-168249
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cytokine Signaling in Immune system R-HSA-1280215
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of GLI1 by the proteasome R-HSA-5610780
Programmed Cell Death R-HSA-5357801
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of DVL R-HSA-4641258
Degradation of beta-catenin by the destruction complex R-HSA-195253
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic Metaphase and Anaphase R-HSA-2555396
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX2 R-HSA-8878166
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
PIP3 activates AKT signaling R-HSA-1257604
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Defective CFTR causes cystic fibrosis R-HSA-5678895
Interleukin-1 signaling R-HSA-9020702
Neddylation R-HSA-8951664
Cell Cycle, Mitotic R-HSA-69278
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PTEN Regulation R-HSA-6807070
Hedgehog 'on' state R-HSA-5632684
Post-translational protein modification R-HSA-597592
Separation of Sister Chromatids R-HSA-2467813
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of RNA R-HSA-8953854
Mitotic Anaphase R-HSA-68882
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism R-HSA-1430728
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Developmental Biology R-HSA-1266738
Cellular response to hypoxia R-HSA-1234174
Regulation of PTEN stability and activity R-HSA-8948751
Degradation of GLI2 by the proteasome R-HSA-5610783
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of expression of SLITs and ROBOs R-HSA-9010553
M Phase R-HSA-68886
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication R-HSA-69306
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of amino acids and derivatives R-HSA-71291
Immune System R-HSA-168256
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle Checkpoints R-HSA-69620
PCP/CE pathway R-HSA-4086400
Cell Cycle Checkpoints R-HSA-69620
UCH proteinases R-HSA-5689603
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of polyamines R-HSA-351202
TCR signaling R-HSA-202403
M Phase R-HSA-68886
Infectious disease R-HSA-5663205
Degradation of GLI2 by the proteasome R-HSA-5610783
Separation of Sister Chromatids R-HSA-2467813
Cellular response to hypoxia R-HSA-1234174
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants abrogate ligand secretion R-HSA-5387390
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by ROBO receptors R-HSA-376176
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of amino acids and derivatives R-HSA-71291
S Phase R-HSA-69242
Axon guidance R-HSA-422475
Signaling by Interleukins R-HSA-449147
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic G2-G2/M phases R-HSA-453274
Class I MHC mediated antigen processing & presentation R-HSA-983169
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic Anaphase R-HSA-68882
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle R-HSA-1640170
Degradation of AXIN R-HSA-4641257
G2/M Checkpoints R-HSA-69481
Apoptosis R-HSA-109581
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stimuli R-HSA-8953897
Post-translational protein modification R-HSA-597592
Regulation of mitotic cell cycle R-HSA-453276
Defective CFTR causes cystic fibrosis R-HSA-5678895
G2/M Transition R-HSA-69275
HIV Infection R-HSA-162906
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of PTEN stability and activity R-HSA-8948751
Immune System R-HSA-168256
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Metaphase and Anaphase R-HSA-2555396
Antigen processing-Cross presentation R-HSA-1236975
Interleukin-1 family signaling R-HSA-446652
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
Metabolism R-HSA-1430728
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
ER-Phagosome pathway R-HSA-1236974
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stress R-HSA-2262752
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
Adaptive Immune System R-HSA-1280218
Hedgehog ligand biogenesis R-HSA-5358346
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Gene expression (Transcription) R-HSA-74160
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cytokine Signaling in Immune system R-HSA-1280215
C-type lectin receptors (CLRs) R-HSA-5621481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by WNT R-HSA-195721
Disorders of transmembrane transporters R-HSA-5619115
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Signaling by Hedgehog R-HSA-5358351
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RAS by GAPs R-HSA-5658442
Degradation of DVL R-HSA-4641258
Cellular response to chemical stress R-HSA-9711123
DNA Replication R-HSA-69306
Hh mutants are degraded by ERAD R-HSA-5362768
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
RAF/MAP kinase cascade R-HSA-5673001
Degradation of beta-catenin by the destruction complex R-HSA-195253
MAPK family signaling cascades R-HSA-5683057
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog 'off' state R-HSA-5610787
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
Metabolism of proteins R-HSA-392499
MAPK6/MAPK4 signaling R-HSA-5687128
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
ABC transporter disorders R-HSA-5619084
Generic Transcription Pathway R-HSA-212436
Innate Immune System R-HSA-168249
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Intracellular signaling by second messengers R-HSA-9006925
Downstream TCR signaling R-HSA-202424
Metabolism R-HSA-1430728
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RAS by GAPs R-HSA-5658442
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Switching of origins to a post-replicative state R-HSA-69052
Adaptive Immune System R-HSA-1280218
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Generic Transcription Pathway R-HSA-212436
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Separation of Sister Chromatids R-HSA-2467813
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TCR signaling R-HSA-202403
Interleukin-1 signaling R-HSA-9020702
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic Anaphase R-HSA-68882
UCH proteinases R-HSA-5689603
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of PTEN stability and activity R-HSA-8948751
Ub-specific processing proteases R-HSA-5689880
Deubiquitination R-HSA-5688426
Signaling by Hedgehog R-HSA-5358351
Synthesis of DNA R-HSA-69239
ER-Phagosome pathway R-HSA-1236974
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle Checkpoints R-HSA-69620
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of proteins R-HSA-392499
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Class I MHC mediated antigen processing & presentation R-HSA-983169
Nervous system development R-HSA-9675108
Activation of NF-kappaB in B cells R-HSA-1169091
Infectious disease R-HSA-5663205
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of mitotic cell cycle R-HSA-453276
Downstream TCR signaling R-HSA-202424
KEAP1-NFE2L2 pathway R-HSA-9755511
G2/M Checkpoints R-HSA-69481
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Axon guidance R-HSA-422475
Cell Cycle, Mitotic R-HSA-69278
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PCP/CE pathway R-HSA-4086400
Signaling by WNT R-HSA-195721
Antigen processing-Cross presentation R-HSA-1236975
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
NIK-->noncanonical NF-kB signaling R-HSA-5676590
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle R-HSA-1640170
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hh mutants abrogate ligand secretion R-HSA-5387390
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog 'on' state R-HSA-5632684
Vpu mediated degradation of CD4 R-HSA-180534
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Mitotic Metaphase and Anaphase R-HSA-2555396
Immune System R-HSA-168256
Regulation of Apoptosis R-HSA-169911
Hh mutants are degraded by ERAD R-HSA-5362768
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of AXIN R-HSA-4641257
p53-Independent DNA Damage Response R-HSA-69610
Host Interactions of HIV factors R-HSA-162909
RNA Polymerase II Transcription R-HSA-73857
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Apoptosis R-HSA-109581
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of polyamines R-HSA-351202
p53-Dependent G1 DNA Damage Response R-HSA-69563
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
Post-translational protein modification R-HSA-597592
Metabolism of amino acids and derivatives R-HSA-71291
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of DVL R-HSA-4641258
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
HIV Infection R-HSA-162906
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
Disease R-HSA-1643685
Programmed Cell Death R-HSA-5357801
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular response to hypoxia R-HSA-1234174
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Stabilization of p53 R-HSA-69541
Gene expression (Transcription) R-HSA-74160
Transport of small molecules R-HSA-382551
Disorders of transmembrane transporters R-HSA-5619115
Cellular response to chemical stress R-HSA-9711123
Intracellular signaling by second messengers R-HSA-9006925
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of proteins R-HSA-392499
Cellular response to hypoxia R-HSA-1234174
Nervous system development R-HSA-9675108
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
ABC-family proteins mediated transport R-HSA-382556
Downstream TCR signaling R-HSA-202424
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RAS by GAPs R-HSA-5658442
Regulation of mitotic cell cycle R-HSA-453276
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular responses to stimuli R-HSA-8953897
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle R-HSA-1640170
Innate Immune System R-HSA-168249
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent DNA Damage Response R-HSA-69610
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
Neddylation R-HSA-8951664
Post-translational protein modification R-HSA-597592
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of AXIN R-HSA-4641257
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of Apoptosis R-HSA-169911
Degradation of DVL R-HSA-4641258
MAPK1/MAPK3 signaling R-HSA-5684996
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
ER-Phagosome pathway R-HSA-1236974
Metabolism R-HSA-1430728
Synthesis of DNA R-HSA-69239
Cellular response to chemical stress R-HSA-9711123
Degradation of GLI1 by the proteasome R-HSA-5610780
RNA Polymerase II Transcription R-HSA-73857
Signaling by ROBO receptors R-HSA-376176
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by WNT R-HSA-195721
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by Hedgehog R-HSA-5358351
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular responses to stress R-HSA-2262752
Hedgehog 'on' state R-HSA-5632684
G1/S DNA Damage Checkpoints R-HSA-69615
Hedgehog 'off' state R-HSA-5610787
S Phase R-HSA-69242
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Programmed Cell Death R-HSA-5357801
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
M Phase R-HSA-68886
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
UCH proteinases R-HSA-5689603
PIP3 activates AKT signaling R-HSA-1257604
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Generic Transcription Pathway R-HSA-212436
Cell Cycle, Mitotic R-HSA-69278
Separation of Sister Chromatids R-HSA-2467813
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of polyamines R-HSA-351202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic Anaphase R-HSA-68882
Deubiquitination R-HSA-5688426
Mitotic G2-G2/M phases R-HSA-453274
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
G2/M Transition R-HSA-69275
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Stabilization of p53 R-HSA-69541
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
PTEN Regulation R-HSA-6807070
MAPK6/MAPK4 signaling R-HSA-5687128
TCR signaling R-HSA-202403
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Orc1 removal from chromatin R-HSA-68949
HIV Infection R-HSA-162906
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Infectious disease R-HSA-5663205
Hh mutants are degraded by ERAD R-HSA-5362768
Cytokine Signaling in Immune system R-HSA-1280215
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
Metabolism of RNA R-HSA-8953854
Transport of small molecules R-HSA-382551
Metabolism of amino acids and derivatives R-HSA-71291
Vpu mediated degradation of CD4 R-HSA-180534
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Regulation of RUNX2 expression and activity R-HSA-8939902
Ub-specific processing proteases R-HSA-5689880
Vif-mediated degradation of APOBEC3G R-HSA-180585
G2/M Checkpoints R-HSA-69481
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication R-HSA-69306
Asymmetric localization of PCP proteins R-HSA-4608870
Intracellular signaling by second messengers R-HSA-9006925
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TCR signaling R-HSA-202403
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of RAS by GAPs R-HSA-5658442
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 family signaling R-HSA-446652
Hedgehog 'on' state R-HSA-5632684
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of PTEN stability and activity R-HSA-8948751
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G1/S DNA Damage Checkpoints R-HSA-69615
ABC transporter disorders R-HSA-5619084
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by Interleukins R-HSA-449147
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK family signaling cascades R-HSA-5683057
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by WNT R-HSA-195721
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle Checkpoints R-HSA-69620
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Orc1 removal from chromatin R-HSA-68949
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of Apoptosis R-HSA-169911
Neddylation R-HSA-8951664
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FCERI mediated NF-kB activation R-HSA-2871837
Transport of small molecules R-HSA-382551
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by Hedgehog R-HSA-5358351
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 signaling R-HSA-9020702
Cellular response to chemical stress R-HSA-9711123
Degradation of DVL R-HSA-4641258
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
UCH proteinases R-HSA-5689603
Immune System R-HSA-168256
p53-Independent DNA Damage Response R-HSA-69610
G2/M Transition R-HSA-69275
Hedgehog 'off' state R-HSA-5610787
Degradation of AXIN R-HSA-4641257
MAPK6/MAPK4 signaling R-HSA-5687128
Nervous system development R-HSA-9675108
Gene expression (Transcription) R-HSA-74160
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle R-HSA-1640170
HIV Infection R-HSA-162906
Infectious disease R-HSA-5663205
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Checkpoints R-HSA-69481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ER-Phagosome pathway R-HSA-1236974
PCP/CE pathway R-HSA-4086400
Vif-mediated degradation of APOBEC3G R-HSA-180585
Programmed Cell Death R-HSA-5357801
Synthesis of DNA R-HSA-69239
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism R-HSA-1430728
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular responses to stimuli R-HSA-8953897
M Phase R-HSA-68886
Axon guidance R-HSA-422475
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Developmental Biology R-HSA-1266738
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
Ub-specific processing proteases R-HSA-5689880
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hh mutants abrogate ligand secretion R-HSA-5387390
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
PTEN Regulation R-HSA-6807070
Metabolism of RNA R-HSA-8953854
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
Vpu mediated degradation of CD4 R-HSA-180534
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to hypoxia R-HSA-1234174
S Phase R-HSA-69242
Signal Transduction R-HSA-162582
Mitotic Metaphase and Anaphase R-HSA-2555396
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Post-translational protein modification R-HSA-597592
DNA Replication R-HSA-69306
Switching of origins to a post-replicative state R-HSA-69052
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Adaptive Immune System R-HSA-1280218
Metabolism of proteins R-HSA-392499
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of beta-catenin by the destruction complex R-HSA-195253
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Downstream TCR signaling R-HSA-202424
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Innate Immune System R-HSA-168249
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
Beta-catenin independent WNT signaling R-HSA-3858494
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Metaphase and Anaphase R-HSA-2555396
ER-Phagosome pathway R-HSA-1236974
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Post-translational protein modification R-HSA-597592
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
RNA Polymerase II Transcription R-HSA-73857
G2/M Transition R-HSA-69275
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by Interleukins R-HSA-449147
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PIP3 activates AKT signaling R-HSA-1257604
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
UCH proteinases R-HSA-5689603
Nervous system development R-HSA-9675108
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Generic Transcription Pathway R-HSA-212436
Switching of origins to a post-replicative state R-HSA-69052
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of RAS by GAPs R-HSA-5658442
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by WNT R-HSA-195721
Degradation of GLI1 by the proteasome R-HSA-5610780
Separation of Sister Chromatids R-HSA-2467813
HIV Infection R-HSA-162906
Antigen processing-Cross presentation R-HSA-1236975
FCERI mediated NF-kB activation R-HSA-2871837
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
p53-Dependent G1 DNA Damage Response R-HSA-69563
TCF dependent signaling in response to WNT R-HSA-201681
PTEN Regulation R-HSA-6807070
Synthesis of DNA R-HSA-69239
Axon guidance R-HSA-422475
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular response to chemical stress R-HSA-9711123
RAF/MAP kinase cascade R-HSA-5673001
PCP/CE pathway R-HSA-4086400
Metabolism of amino acids and derivatives R-HSA-71291
M Phase R-HSA-68886
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to hypoxia R-HSA-1234174
Neddylation R-HSA-8951664
Mitotic Anaphase R-HSA-68882
Cell Cycle Checkpoints R-HSA-69620
Infectious disease R-HSA-5663205
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Orc1 removal from chromatin R-HSA-68949
Class I MHC mediated antigen processing & presentation R-HSA-983169
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hedgehog 'off' state R-HSA-5610787
Hedgehog 'on' state R-HSA-5632684
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of beta-catenin by the destruction complex R-HSA-195253
MAPK family signaling cascades R-HSA-5683057
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Intracellular signaling by second messengers R-HSA-9006925
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Gene expression (Transcription) R-HSA-74160
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of proteins R-HSA-392499
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of AXIN R-HSA-4641257
Beta-catenin independent WNT signaling R-HSA-3858494
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of RNA R-HSA-8953854
Vif-mediated degradation of APOBEC3G R-HSA-180585
DNA Replication R-HSA-69306
Adaptive Immune System R-HSA-1280218
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cell Cycle, Mitotic R-HSA-69278
Metabolism of polyamines R-HSA-351202
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 signaling R-HSA-9020702
Interleukin-1 family signaling R-HSA-446652
ABC-family proteins mediated transport R-HSA-382556
Signaling by Hedgehog R-HSA-5358351
Transport of small molecules R-HSA-382551
Signal Transduction R-HSA-162582
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disease R-HSA-1643685
Disorders of transmembrane transporters R-HSA-5619115
ABC transporter disorders R-HSA-5619084
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
Hh mutants are degraded by ERAD R-HSA-5362768
Programmed Cell Death R-HSA-5357801
Vpu mediated degradation of CD4 R-HSA-180534
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX2 R-HSA-8878166
Deubiquitination R-HSA-5688426
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream TCR signaling R-HSA-202424
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle R-HSA-1640170
G2/M Checkpoints R-HSA-69481

Expression Atlas ENSG00000154611
NCBI gene (formerly Entrezgene) 143471
GeneCards 22985
HGNC Symbol HGNC:22985
MIM gene 617841
UniProtKB Gene Name Q8TAA3
WikiGene 143471
Gene: PSMB4
Ensembl ID : ENSG00000159377
Description: proteasome 20S subunit beta 4
Gene Synonyms: HN3,PROS26
6 APIs:
214 Possible Orthologues:

UCH proteinases R-HSA-5689603
Assembly of the pre-replicative complex R-HSA-68867
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
Activation of NF-kappaB in B cells R-HSA-1169091
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to chemical stress R-HSA-9711123
Negative regulation of NOTCH4 signaling R-HSA-9604323
TCR signaling R-HSA-202403
Separation of Sister Chromatids R-HSA-2467813
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of AXIN R-HSA-4641257
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ER-Phagosome pathway R-HSA-1236974
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of polyamines R-HSA-351202
Hedgehog ligand biogenesis R-HSA-5358346
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle R-HSA-1640170
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'on' state R-HSA-5632684
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX2 R-HSA-8878166
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
Disease R-HSA-1643685
Mitotic G1 phase and G1/S transition R-HSA-453279
Intracellular signaling by second messengers R-HSA-9006925
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stimuli R-HSA-8953897
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog 'off' state R-HSA-5610787
Cell Cycle, Mitotic R-HSA-69278
Synthesis of DNA R-HSA-69239
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Switching of origins to a post-replicative state R-HSA-69052
ABC transporter disorders R-HSA-5619084
G2/M Transition R-HSA-69275
Vif-mediated degradation of APOBEC3G R-HSA-180585
Vpu mediated degradation of CD4 R-HSA-180534
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of RAS by GAPs R-HSA-5658442
Developmental Biology R-HSA-1266738
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Antigen processing-Cross presentation R-HSA-1236975
Mitotic G2-G2/M phases R-HSA-453274
S Phase R-HSA-69242
Transport of small molecules R-HSA-382551
ABC-family proteins mediated transport R-HSA-382556
Infectious disease R-HSA-5663205
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH4 R-HSA-9013694
Mitotic Anaphase R-HSA-68882
Disorders of transmembrane transporters R-HSA-5619115
G2/M Checkpoints R-HSA-69481
Adaptive Immune System R-HSA-1280218
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants are degraded by ERAD R-HSA-5362768
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Asymmetric localization of PCP proteins R-HSA-4608870
Gene expression (Transcription) R-HSA-74160
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Independent DNA Damage Response R-HSA-69610
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
PTEN Regulation R-HSA-6807070
Regulation of mitotic cell cycle R-HSA-453276
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
Downstream TCR signaling R-HSA-202424
FCERI mediated NF-kB activation R-HSA-2871837
Ub-specific processing proteases R-HSA-5689880
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Post-translational protein modification R-HSA-597592
Signal Transduction R-HSA-162582
DNA Replication R-HSA-69306
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Apoptosis R-HSA-109581
Axon guidance R-HSA-422475
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of DVL R-HSA-4641258
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism R-HSA-1430728
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by NOTCH R-HSA-157118
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by ROBO receptors R-HSA-376176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
HIV Infection R-HSA-162906
Neddylation R-HSA-8951664
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Interleukins R-HSA-449147
Signaling by Hedgehog R-HSA-5358351
Cytokine Signaling in Immune system R-HSA-1280215
Negative regulation of NOTCH4 signaling R-HSA-9604323
DNA Replication Pre-Initiation R-HSA-69002
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog 'off' state R-HSA-5610787
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog ligand biogenesis R-HSA-5358346
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PCP/CE pathway R-HSA-4086400
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of PTEN stability and activity R-HSA-8948751
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Adaptive Immune System R-HSA-1280218
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle, Mitotic R-HSA-69278
Degradation of AXIN R-HSA-4641257
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
Signaling by ROBO receptors R-HSA-376176
Hh mutants abrogate ligand secretion R-HSA-5387390
Orc1 removal from chromatin R-HSA-68949
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC transporter disorders R-HSA-5619084
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
M Phase R-HSA-68886
S Phase R-HSA-69242
Synthesis of DNA R-HSA-69239
RAF/MAP kinase cascade R-HSA-5673001
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX1 R-HSA-8878171
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream TCR signaling R-HSA-202424
G2/M Checkpoints R-HSA-69481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Assembly of the pre-replicative complex R-HSA-68867
Host Interactions of HIV factors R-HSA-162909
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HIV Infection R-HSA-162906
FCERI mediated NF-kB activation R-HSA-2871837
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to hypoxia R-HSA-1234174
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Neddylation R-HSA-8951664
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of RNA R-HSA-8953854
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Hedgehog R-HSA-5358351
TCR signaling R-HSA-202403
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
C-type lectin receptors (CLRs) R-HSA-5621481
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
Axon guidance R-HSA-422475
Immune System R-HSA-168256
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of proteins R-HSA-392499
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transport of small molecules R-HSA-382551
Metabolism of polyamines R-HSA-351202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Switching of origins to a post-replicative state R-HSA-69052
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by WNT R-HSA-195721
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing-Cross presentation R-HSA-1236975
Deubiquitination R-HSA-5688426
Regulation of RUNX2 expression and activity R-HSA-8939902
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by NOTCH4 R-HSA-9013694
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle R-HSA-1640170
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
Separation of Sister Chromatids R-HSA-2467813
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of Apoptosis R-HSA-169911
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular responses to stress R-HSA-2262752
Stabilization of p53 R-HSA-69541
Degradation of DVL R-HSA-4641258
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX3 R-HSA-8878159
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
ER-Phagosome pathway R-HSA-1236974
PTEN Regulation R-HSA-6807070
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK1/MAPK3 signaling R-HSA-5684996
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Vif-mediated degradation of APOBEC3G R-HSA-180585
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cyclin E associated events during G1/S transition R-HSA-69202
Class I MHC mediated antigen processing & presentation R-HSA-983169
RAF/MAP kinase cascade R-HSA-5673001
Host Interactions of HIV factors R-HSA-162909
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Transition R-HSA-69275
Hedgehog 'on' state R-HSA-5632684
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S DNA Damage Checkpoints R-HSA-69615
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stimuli R-HSA-8953897
Neddylation R-HSA-8951664
Vif-mediated degradation of APOBEC3G R-HSA-180585
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of amino acids and derivatives R-HSA-71291
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX2 R-HSA-8878166
Ub-specific processing proteases R-HSA-5689880
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of expression of SLITs and ROBOs R-HSA-9010553
KEAP1-NFE2L2 pathway R-HSA-9755511
Disease R-HSA-1643685
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of DVL R-HSA-4641258
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PIP3 activates AKT signaling R-HSA-1257604
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Anaphase R-HSA-68882
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of DNA R-HSA-69239
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX3 R-HSA-8878159
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 signaling R-HSA-9020702
M Phase R-HSA-68886
Metabolism of polyamines R-HSA-351202
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to hypoxia R-HSA-1234174
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of proteins R-HSA-392499
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interleukin-1 family signaling R-HSA-446652
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transport of small molecules R-HSA-382551
RNA Polymerase II Transcription R-HSA-73857
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by WNT R-HSA-195721
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Regulation of RAS by GAPs R-HSA-5658442
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
HIV Infection R-HSA-162906
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by NOTCH R-HSA-157118
Stabilization of p53 R-HSA-69541
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
ABC transporter disorders R-HSA-5619084
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of AXIN R-HSA-4641257
Hh mutants are degraded by ERAD R-HSA-5362768
Immune System R-HSA-168256
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing-Cross presentation R-HSA-1236975
MAPK6/MAPK4 signaling R-HSA-5687128
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of RNA R-HSA-8953854
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'off' state R-HSA-5610787
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
ER-Phagosome pathway R-HSA-1236974
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of Apoptosis R-HSA-169911
Mitotic G2-G2/M phases R-HSA-453274
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular response to hypoxia R-HSA-1234174
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
Intracellular signaling by second messengers R-HSA-9006925
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Ub-specific processing proteases R-HSA-5689880
Hh mutants are degraded by ERAD R-HSA-5362768
Post-translational protein modification R-HSA-597592
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by WNT R-HSA-195721
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by NOTCH4 R-HSA-9013694
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of DVL R-HSA-4641258
G2/M Transition R-HSA-69275
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle Checkpoints R-HSA-69620
Signaling by ROBO receptors R-HSA-376176
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Interleukin-1 signaling R-HSA-9020702
Generic Transcription Pathway R-HSA-212436
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog ligand biogenesis R-HSA-5358346
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of PTEN stability and activity R-HSA-8948751
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Anaphase R-HSA-68882
Neddylation R-HSA-8951664
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
Axon guidance R-HSA-422475
PTEN Regulation R-HSA-6807070
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
Asymmetric localization of PCP proteins R-HSA-4608870
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
Nervous system development R-HSA-9675108
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX3 R-HSA-8878159
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
Negative regulation of NOTCH4 signaling R-HSA-9604323
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Nuclear events mediated by NFE2L2 R-HSA-9759194
ABC transporter disorders R-HSA-5619084
MAPK1/MAPK3 signaling R-HSA-5684996
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by Interleukins R-HSA-449147
Deubiquitination R-HSA-5688426
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cyclin E associated events during G1/S transition R-HSA-69202
Orc1 removal from chromatin R-HSA-68949
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
PCP/CE pathway R-HSA-4086400
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of RNA R-HSA-8953854
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of proteins R-HSA-392499
Degradation of AXIN R-HSA-4641257
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Gene expression (Transcription) R-HSA-74160
Host Interactions of HIV factors R-HSA-162909
Infectious disease R-HSA-5663205
Developmental Biology R-HSA-1266738
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Stabilization of p53 R-HSA-69541
Hedgehog 'on' state R-HSA-5632684
Innate Immune System R-HSA-168249
HIV Infection R-HSA-162906
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RAF/MAP kinase cascade R-HSA-5673001
Synthesis of DNA R-HSA-69239
Switching of origins to a post-replicative state R-HSA-69052
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent DNA Damage Response R-HSA-69610
UCH proteinases R-HSA-5689603
Metabolism R-HSA-1430728
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX2 expression and activity R-HSA-8939902
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of AXIN R-HSA-4641257
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Mitotic Anaphase R-HSA-68882
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
UCH proteinases R-HSA-5689603
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle, Mitotic R-HSA-69278
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hh mutants abrogate ligand secretion R-HSA-5387390
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX1 R-HSA-8878171
Transport of small molecules R-HSA-382551
Innate Immune System R-HSA-168249
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RUNX3 expression and activity R-HSA-8941858
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Orc1 removal from chromatin R-HSA-68949
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Cellular responses to stress R-HSA-2262752
Metabolism of RNA R-HSA-8953854
Asymmetric localization of PCP proteins R-HSA-4608870
Adaptive Immune System R-HSA-1280218
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Signaling by NOTCH4 R-HSA-9013694
CLEC7A (Dectin-1) signaling R-HSA-5607764
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog ligand biogenesis R-HSA-5358346
HIV Infection R-HSA-162906
Cellular response to chemical stress R-HSA-9711123
Synthesis of DNA R-HSA-69239
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
S Phase R-HSA-69242
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by WNT R-HSA-195721
Metabolism of proteins R-HSA-392499
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stimuli R-HSA-8953897
Axon guidance R-HSA-422475
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mitotic cell cycle R-HSA-453276
Class I MHC mediated antigen processing & presentation R-HSA-983169
Nervous system development R-HSA-9675108
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
Signaling by ROBO receptors R-HSA-376176
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of DVL R-HSA-4641258
Neddylation R-HSA-8951664
Host Interactions of HIV factors R-HSA-162909
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Vpu mediated degradation of CD4 R-HSA-180534
Stabilization of p53 R-HSA-69541
Assembly of the pre-replicative complex R-HSA-68867
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI1 by the proteasome R-HSA-5610780
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Downstream TCR signaling R-HSA-202424
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Replication R-HSA-69306
Signaling by Interleukins R-HSA-449147
G2/M Checkpoints R-HSA-69481
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Antigen processing-Cross presentation R-HSA-1236975
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX3 R-HSA-8878159
RAF/MAP kinase cascade R-HSA-5673001
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disease R-HSA-1643685
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
ER-Phagosome pathway R-HSA-1236974
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism R-HSA-1430728
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
TCR signaling R-HSA-202403
Signaling by Hedgehog R-HSA-5358351
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Interleukin-1 family signaling R-HSA-446652
Disorders of transmembrane transporters R-HSA-5619115
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
Innate Immune System R-HSA-168249
Stabilization of p53 R-HSA-69541
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Apoptosis R-HSA-109581
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
DNA Replication R-HSA-69306
Ub-specific processing proteases R-HSA-5689880
Infectious disease R-HSA-5663205
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PIP3 activates AKT signaling R-HSA-1257604
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of AXIN R-HSA-4641257
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by NOTCH4 R-HSA-9013694
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hh mutants are degraded by ERAD R-HSA-5362768
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism R-HSA-1430728
Nuclear events mediated by NFE2L2 R-HSA-9759194
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication Pre-Initiation R-HSA-69002
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PCP/CE pathway R-HSA-4086400
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stimuli R-HSA-8953897
Mitotic Anaphase R-HSA-68882
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
C-type lectin receptors (CLRs) R-HSA-5621481
Axon guidance R-HSA-422475
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
TCR signaling R-HSA-202403
Regulation of mitotic cell cycle R-HSA-453276
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'off' state R-HSA-5610787
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH R-HSA-157118
Transport of small molecules R-HSA-382551
Nervous system development R-HSA-9675108
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
KEAP1-NFE2L2 pathway R-HSA-9755511
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Programmed Cell Death R-HSA-5357801
Degradation of DVL R-HSA-4641258
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of amino acids and derivatives R-HSA-71291
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream TCR signaling R-HSA-202424
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
G1/S DNA Damage Checkpoints R-HSA-69615
Generic Transcription Pathway R-HSA-212436
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular response to hypoxia R-HSA-1234174
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle R-HSA-1640170
Metabolism of proteins R-HSA-392499
Hedgehog 'on' state R-HSA-5632684
Post-translational protein modification R-HSA-597592
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
TCF dependent signaling in response to WNT R-HSA-201681
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Antigen processing-Cross presentation R-HSA-1236975
Assembly of the pre-replicative complex R-HSA-68867
ABC transporter disorders R-HSA-5619084
ABC-family proteins mediated transport R-HSA-382556
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular response to chemical stress R-HSA-9711123
Regulation of RAS by GAPs R-HSA-5658442
UCH proteinases R-HSA-5689603
G1/S Transition R-HSA-69206
Signal Transduction R-HSA-162582
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX3 R-HSA-8878159
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of GLI2 by the proteasome R-HSA-5610783
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G1 phase and G1/S transition R-HSA-453279
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
Downstream TCR signaling R-HSA-202424
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Assembly of the pre-replicative complex R-HSA-68867
ABC transporter disorders R-HSA-5619084
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Apoptosis R-HSA-109581
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Innate Immune System R-HSA-168249
Mitotic Metaphase and Anaphase R-HSA-2555396
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
Disorders of transmembrane transporters R-HSA-5619115
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
Immune System R-HSA-168256
MAPK family signaling cascades R-HSA-5683057
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of RNA R-HSA-8953854
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
M Phase R-HSA-68886
Transport of small molecules R-HSA-382551
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vpu mediated degradation of CD4 R-HSA-180534
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants abrogate ligand secretion R-HSA-5387390
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog ligand biogenesis R-HSA-5358346
Neddylation R-HSA-8951664
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
Cellular responses to stimuli R-HSA-8953897
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
MAPK1/MAPK3 signaling R-HSA-5684996
ER-Phagosome pathway R-HSA-1236974
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
PIP3 activates AKT signaling R-HSA-1257604
HIV Infection R-HSA-162906
Signaling by WNT R-HSA-195721
G2/M Checkpoints R-HSA-69481
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Disease R-HSA-1643685
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of Apoptosis R-HSA-169911
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Deubiquitination R-HSA-5688426
Nervous system development R-HSA-9675108
Activation of NF-kappaB in B cells R-HSA-1169091
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of AXIN R-HSA-4641257
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle, Mitotic R-HSA-69278
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Synthesis of DNA R-HSA-69239
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Signaling by Interleukins R-HSA-449147
Signaling by NOTCH R-HSA-157118
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
Stabilization of p53 R-HSA-69541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PCP/CE pathway R-HSA-4086400
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
DNA Replication R-HSA-69306
Signaling by NOTCH4 R-HSA-9013694
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by the B Cell Receptor (BCR) R-HSA-983705
DNA Replication Pre-Initiation R-HSA-69002
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular responses to stress R-HSA-2262752
Separation of Sister Chromatids R-HSA-2467813
Cellular response to chemical stress R-HSA-9711123
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
Hedgehog 'on' state R-HSA-5632684
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
NIK-->noncanonical NF-kB signaling R-HSA-5676590
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by ROBO receptors R-HSA-376176
Metabolism of polyamines R-HSA-351202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX1 R-HSA-8878171
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Negative regulation of NOTCH4 signaling R-HSA-9604323
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Programmed Cell Death R-HSA-5357801
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of proteins R-HSA-392499
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to hypoxia R-HSA-1234174
Nuclear events mediated by NFE2L2 R-HSA-9759194
Neddylation R-HSA-8951664
Hedgehog 'on' state R-HSA-5632684
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RAS by GAPs R-HSA-5658442
DNA Replication R-HSA-69306
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation by RUNX2 R-HSA-8878166
Negative regulation of NOTCH4 signaling R-HSA-9604323
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hh mutants are degraded by ERAD R-HSA-5362768
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle, Mitotic R-HSA-69278
PCP/CE pathway R-HSA-4086400
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of Apoptosis R-HSA-169911
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic G2-G2/M phases R-HSA-453274
G2/M Transition R-HSA-69275
Switching of origins to a post-replicative state R-HSA-69052
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ER-Phagosome pathway R-HSA-1236974
Innate Immune System R-HSA-168249
Post-translational protein modification R-HSA-597592
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK family signaling cascades R-HSA-5683057
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M Checkpoints R-HSA-69481
Regulation of RUNX2 expression and activity R-HSA-8939902
Cytokine Signaling in Immune system R-HSA-1280215
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
C-type lectin receptors (CLRs) R-HSA-5621481
M Phase R-HSA-68886
Beta-catenin independent WNT signaling R-HSA-3858494
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Antigen processing-Cross presentation R-HSA-1236975
p53-Independent DNA Damage Response R-HSA-69610
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Synthesis of DNA R-HSA-69239
DNA Replication Pre-Initiation R-HSA-69002
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
Signaling by WNT R-HSA-195721
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Disorders of transmembrane transporters R-HSA-5619115
KEAP1-NFE2L2 pathway R-HSA-9755511
Deubiquitination R-HSA-5688426
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle Checkpoints R-HSA-69620
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Intracellular signaling by second messengers R-HSA-9006925
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Adaptive Immune System R-HSA-1280218
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of RNA R-HSA-8953854
Cellular responses to stimuli R-HSA-8953897
Degradation of DVL R-HSA-4641258
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic Anaphase R-HSA-68882
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
FCERI mediated NF-kB activation R-HSA-2871837
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog ligand biogenesis R-HSA-5358346
RAF/MAP kinase cascade R-HSA-5673001
Regulation of PTEN stability and activity R-HSA-8948751
Developmental Biology R-HSA-1266738
Cellular response to chemical stress R-HSA-9711123
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Apoptosis R-HSA-109581
Immune System R-HSA-168256
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle R-HSA-1640170
TCR signaling R-HSA-202403
Signaling by the B Cell Receptor (BCR) R-HSA-983705
HIV Infection R-HSA-162906
Regulation of RUNX3 expression and activity R-HSA-8941858
PTEN Regulation R-HSA-6807070
Metabolism R-HSA-1430728
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ub-specific processing proteases R-HSA-5689880
Signaling by Hedgehog R-HSA-5358351
Regulation of mitotic cell cycle R-HSA-453276
Signaling by NOTCH4 R-HSA-9013694
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signal Transduction R-HSA-162582
Signaling by ROBO receptors R-HSA-376176
PIP3 activates AKT signaling R-HSA-1257604
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Host Interactions of HIV factors R-HSA-162909
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of amino acids and derivatives R-HSA-71291
Programmed Cell Death R-HSA-5357801
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
CLEC7A (Dectin-1) signaling R-HSA-5607764
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by ROBO receptors R-HSA-376176
ABC-family proteins mediated transport R-HSA-382556
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to chemical stress R-HSA-9711123
Immune System R-HSA-168256
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RAS by GAPs R-HSA-5658442
G2/M Transition R-HSA-69275
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism R-HSA-1430728
Hedgehog ligand biogenesis R-HSA-5358346
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Infectious disease R-HSA-5663205
MAPK6/MAPK4 signaling R-HSA-5687128
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
Interleukin-1 signaling R-HSA-9020702
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of polyamines R-HSA-351202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'off' state R-HSA-5610787
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of amino acids and derivatives R-HSA-71291
G1/S Transition R-HSA-69206
TCR signaling R-HSA-202403
Cellular responses to stress R-HSA-2262752
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Disease R-HSA-1643685
G2/M Checkpoints R-HSA-69481
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
ABC transporter disorders R-HSA-5619084
Separation of Sister Chromatids R-HSA-2467813
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G1 phase and G1/S transition R-HSA-453279
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Programmed Cell Death R-HSA-5357801
M Phase R-HSA-68886
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
Cellular response to hypoxia R-HSA-1234174
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX1 R-HSA-8878171
Neddylation R-HSA-8951664
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Host Interactions of HIV factors R-HSA-162909
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
PCP/CE pathway R-HSA-4086400
Antigen processing-Cross presentation R-HSA-1236975
Asymmetric localization of PCP proteins R-HSA-4608870
Apoptosis R-HSA-109581
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Innate Immune System R-HSA-168249
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
Transcriptional regulation by RUNX3 R-HSA-8878159
Intracellular signaling by second messengers R-HSA-9006925
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Axon guidance R-HSA-422475
S Phase R-HSA-69242
Signaling by WNT R-HSA-195721
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of RNA R-HSA-8953854
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Stabilization of p53 R-HSA-69541
Switching of origins to a post-replicative state R-HSA-69052
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of AXIN R-HSA-4641257
Vif-mediated degradation of APOBEC3G R-HSA-180585
Defective CFTR causes cystic fibrosis R-HSA-5678895
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
PTEN Regulation R-HSA-6807070
Adaptive Immune System R-HSA-1280218
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX2 R-HSA-8878166
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cyclin E associated events during G1/S transition R-HSA-69202
Activation of NF-kappaB in B cells R-HSA-1169091
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Disease R-HSA-1643685
Asymmetric localization of PCP proteins R-HSA-4608870
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Transition R-HSA-69275
ABC-family proteins mediated transport R-HSA-382556
DNA Replication R-HSA-69306
Regulation of RAS by GAPs R-HSA-5658442
Regulation of RUNX2 expression and activity R-HSA-8939902
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Programmed Cell Death R-HSA-5357801
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent DNA Damage Response R-HSA-69610
Innate Immune System R-HSA-168249
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Beta-catenin independent WNT signaling R-HSA-3858494
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Synthesis of DNA R-HSA-69239
Signaling by Hedgehog R-HSA-5358351
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication Pre-Initiation R-HSA-69002
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCR signaling R-HSA-202403
Defective CFTR causes cystic fibrosis R-HSA-5678895
Apoptosis R-HSA-109581
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular response to chemical stress R-HSA-9711123
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Post-translational protein modification R-HSA-597592
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK family signaling cascades R-HSA-5683057
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stress R-HSA-2262752
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'on' state R-HSA-5632684
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
M Phase R-HSA-68886
Immune System R-HSA-168256
Gene expression (Transcription) R-HSA-74160
S Phase R-HSA-69242
Adaptive Immune System R-HSA-1280218
G2/M Checkpoints R-HSA-69481
Negative regulation of NOTCH4 signaling R-HSA-9604323
RNA Polymerase II Transcription R-HSA-73857
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
HIV Infection R-HSA-162906
Cell Cycle R-HSA-1640170
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Interleukins R-HSA-449147
CLEC7A (Dectin-1) signaling R-HSA-5607764
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Downstream TCR signaling R-HSA-202424
Metabolism of polyamines R-HSA-351202
Regulation of PTEN stability and activity R-HSA-8948751
Infectious disease R-HSA-5663205
Interleukin-1 signaling R-HSA-9020702
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mitotic cell cycle R-HSA-453276
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
Generic Transcription Pathway R-HSA-212436
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hedgehog 'off' state R-HSA-5610787
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Separation of Sister Chromatids R-HSA-2467813
Degradation of DVL R-HSA-4641258
Metabolism of RNA R-HSA-8953854
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of proteins R-HSA-392499
Metabolism of amino acids and derivatives R-HSA-71291
PCP/CE pathway R-HSA-4086400
Transport of small molecules R-HSA-382551
Vpu mediated degradation of CD4 R-HSA-180534
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G2-G2/M phases R-HSA-453274
Neddylation R-HSA-8951664
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism R-HSA-1430728
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing-Cross presentation R-HSA-1236975
Nervous system development R-HSA-9675108
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
C-type lectin receptors (CLRs) R-HSA-5621481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Host Interactions of HIV factors R-HSA-162909
Disorders of transmembrane transporters R-HSA-5619115
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle Checkpoints R-HSA-69620
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic Anaphase R-HSA-68882
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1 DNA Damage Response R-HSA-69563
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RNA Polymerase II Transcription R-HSA-73857
Orc1 removal from chromatin R-HSA-68949
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Nuclear events mediated by NFE2L2 R-HSA-9759194
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of AXIN R-HSA-4641257
Cell Cycle R-HSA-1640170
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by ROBO receptors R-HSA-376176
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to hypoxia R-HSA-1234174
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication Pre-Initiation R-HSA-69002
ABC transporter disorders R-HSA-5619084
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Infectious disease R-HSA-5663205
Metabolism of RNA R-HSA-8953854
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
DNA Replication R-HSA-69306
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PTEN Regulation R-HSA-6807070
Synthesis of DNA R-HSA-69239
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Post-translational protein modification R-HSA-597592
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
Metabolism R-HSA-1430728
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle, Mitotic R-HSA-69278
Signaling by NOTCH R-HSA-157118
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog ligand biogenesis R-HSA-5358346
Programmed Cell Death R-HSA-5357801
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
Disorders of transmembrane transporters R-HSA-5619115
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic Anaphase R-HSA-68882
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transport of small molecules R-HSA-382551
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
G1/S Transition R-HSA-69206
Interleukin-1 family signaling R-HSA-446652
Regulation of mitotic cell cycle R-HSA-453276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of beta-catenin by the destruction complex R-HSA-195253
Separation of Sister Chromatids R-HSA-2467813
Regulation of RUNX3 expression and activity R-HSA-8941858
ER-Phagosome pathway R-HSA-1236974
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK1/MAPK3 signaling R-HSA-5684996
HIV Infection R-HSA-162906
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'off' state R-HSA-5610787
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Apoptosis R-HSA-109581
Intracellular signaling by second messengers R-HSA-9006925
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Assembly of the pre-replicative complex R-HSA-68867
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
G2/M Checkpoints R-HSA-69481
CLEC7A (Dectin-1) signaling R-HSA-5607764
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RAS by GAPs R-HSA-5658442
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX2 R-HSA-8878166
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle Checkpoints R-HSA-69620
MAPK family signaling cascades R-HSA-5683057
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
Regulation of Apoptosis R-HSA-169911
PCP/CE pathway R-HSA-4086400
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Disease R-HSA-1643685
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Independent DNA Damage Response R-HSA-69610
Axon guidance R-HSA-422475
Mitotic G2-G2/M phases R-HSA-453274
RAF/MAP kinase cascade R-HSA-5673001
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stress R-HSA-2262752
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
Adaptive Immune System R-HSA-1280218
Deubiquitination R-HSA-5688426
Innate Immune System R-HSA-168249
Metabolism of polyamines R-HSA-351202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202

Expression Atlas ENSG00000159377
NCBI gene (formerly Entrezgene) 5692
GeneCards 9541
HGNC Symbol HGNC:9541
MIM gene 602177
MIM morbid 617591
UniProtKB Gene Name P28070
WikiGene 5692
Gene: PSMD11
Ensembl ID : ENSG00000108671
Description: proteasome 26S subunit, non-ATPase 11
Gene Synonyms: MGC3844,P44.5,RPN6,S9
5 APIs:
283 Possible Orthologues:

DNA Replication R-HSA-69306
Metabolism R-HSA-1430728
Programmed Cell Death R-HSA-5357801
Adaptive Immune System R-HSA-1280218
Activation of NF-kappaB in B cells R-HSA-1169091
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nuclear events mediated by NFE2L2 R-HSA-9759194
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of GLI1 by the proteasome R-HSA-5610780
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
MAPK family signaling cascades R-HSA-5683057
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'on' state R-HSA-5632684
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX1 R-HSA-8878171
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
Intracellular signaling by second messengers R-HSA-9006925
Separation of Sister Chromatids R-HSA-2467813
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle, Mitotic R-HSA-69278
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by WNT R-HSA-195721
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RAF/MAP kinase cascade R-HSA-5673001
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Hedgehog R-HSA-5358351
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
S Phase R-HSA-69242
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Immune System R-HSA-168256
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of RNA R-HSA-8953854
Stabilization of p53 R-HSA-69541
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular response to hypoxia R-HSA-1234174
Mitotic G1 phase and G1/S transition R-HSA-453279
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Downstream TCR signaling R-HSA-202424
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vpu mediated degradation of CD4 R-HSA-180534
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog 'off' state R-HSA-5610787
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism R-HSA-1430728
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
HIV Infection R-HSA-162906
ER-Phagosome pathway R-HSA-1236974
Apoptosis R-HSA-109581
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by NOTCH4 R-HSA-9013694
Neutrophil degranulation R-HSA-6798695
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
p53-Dependent G1 DNA Damage Response R-HSA-69563
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disease R-HSA-1643685
G1/S DNA Damage Checkpoints R-HSA-69615
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
Metabolism of polyamines R-HSA-351202
Deubiquitination R-HSA-5688426
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Metaphase and Anaphase R-HSA-2555396
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cyclin E associated events during G1/S transition R-HSA-69202
G2/M Transition R-HSA-69275
Degradation of AXIN R-HSA-4641257
Assembly of the pre-replicative complex R-HSA-68867
Hh mutants are degraded by ERAD R-HSA-5362768
Vif-mediated degradation of APOBEC3G R-HSA-180585
Generic Transcription Pathway R-HSA-212436
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stress R-HSA-2262752
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
Signal Transduction R-HSA-162582
Mitotic Anaphase R-HSA-68882
Ub-specific processing proteases R-HSA-5689880
TCR signaling R-HSA-202403
Cell Cycle Checkpoints R-HSA-69620
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RUNX3 expression and activity R-HSA-8941858
DNA Replication Pre-Initiation R-HSA-69002
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI2 by the proteasome R-HSA-5610783
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX2 R-HSA-8878166
ABC transporter disorders R-HSA-5619084
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX3 R-HSA-8878159
Defective CFTR causes cystic fibrosis R-HSA-5678895
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Gene expression (Transcription) R-HSA-74160
Signaling by ROBO receptors R-HSA-376176
Regulation of Apoptosis R-HSA-169911
UCH proteinases R-HSA-5689603
Cytokine Signaling in Immune system R-HSA-1280215
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
Hh mutants abrogate ligand secretion R-HSA-5387390
Synthesis of DNA R-HSA-69239
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of amino acids and derivatives R-HSA-71291
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Host Interactions of HIV factors R-HSA-162909
Nervous system development R-HSA-9675108
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Neddylation R-HSA-8951664
Negative regulation of NOTCH4 signaling R-HSA-9604323
MAPK6/MAPK4 signaling R-HSA-5687128
M Phase R-HSA-68886
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Dependent G1 DNA Damage Response R-HSA-69563
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI2 by the proteasome R-HSA-5610783
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
FCERI mediated NF-kB activation R-HSA-2871837
Programmed Cell Death R-HSA-5357801
DNA Replication R-HSA-69306
C-type lectin receptors (CLRs) R-HSA-5621481
Host Interactions of HIV factors R-HSA-162909
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCR signaling R-HSA-202403
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
Hedgehog 'on' state R-HSA-5632684
Mitotic Metaphase and Anaphase R-HSA-2555396
M Phase R-HSA-68886
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
Apoptosis R-HSA-109581
Disease R-HSA-1643685
Transcriptional regulation by RUNX3 R-HSA-8878159
Assembly of the pre-replicative complex R-HSA-68867
Deubiquitination R-HSA-5688426
Downstream TCR signaling R-HSA-202424
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Anaphase R-HSA-68882
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of DVL R-HSA-4641258
MAPK family signaling cascades R-HSA-5683057
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI1 by the proteasome R-HSA-5610780
RAF/MAP kinase cascade R-HSA-5673001
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle R-HSA-1640170
Metabolism of RNA R-HSA-8953854
Activation of NF-kappaB in B cells R-HSA-1169091
Hedgehog 'off' state R-HSA-5610787
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by NOTCH R-HSA-157118
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S DNA Damage Checkpoints R-HSA-69615
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Negative regulation of NOTCH4 signaling R-HSA-9604323
Neutrophil degranulation R-HSA-6798695
Gene expression (Transcription) R-HSA-74160
ABC transporter disorders R-HSA-5619084
Transport of small molecules R-HSA-382551
ER-Phagosome pathway R-HSA-1236974
Developmental Biology R-HSA-1266738
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Generic Transcription Pathway R-HSA-212436
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Interleukins R-HSA-449147
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
PIP3 activates AKT signaling R-HSA-1257604
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
Neddylation R-HSA-8951664
Vif-mediated degradation of APOBEC3G R-HSA-180585
Nervous system development R-HSA-9675108
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of proteins R-HSA-392499
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
Disorders of transmembrane transporters R-HSA-5619115
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle Checkpoints R-HSA-69620
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Cellular responses to stimuli R-HSA-8953897
Orc1 removal from chromatin R-HSA-68949
Metabolism of amino acids and derivatives R-HSA-71291
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle, Mitotic R-HSA-69278
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of polyamines R-HSA-351202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants are degraded by ERAD R-HSA-5362768
HIV Infection R-HSA-162906
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RAS by GAPs R-HSA-5658442
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
Cellular response to hypoxia R-HSA-1234174
Cellular response to chemical stress R-HSA-9711123
S Phase R-HSA-69242
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
Adaptive Immune System R-HSA-1280218
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Post-translational protein modification R-HSA-597592
Cellular responses to stress R-HSA-2262752
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S Transition R-HSA-69206
Synthesis of DNA R-HSA-69239
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Class I MHC mediated antigen processing & presentation R-HSA-983169
Intracellular signaling by second messengers R-HSA-9006925
PCP/CE pathway R-HSA-4086400
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by ROBO receptors R-HSA-376176
Mitotic G2-G2/M phases R-HSA-453274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH4 R-HSA-9013694
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mitotic cell cycle R-HSA-453276
Orc1 removal from chromatin R-HSA-68949
Vif-mediated degradation of APOBEC3G R-HSA-180585
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'on' state R-HSA-5632684
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Innate Immune System R-HSA-168249
Degradation of DVL R-HSA-4641258
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Cell Cycle, Mitotic R-HSA-69278
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by the B Cell Receptor (BCR) R-HSA-983705
KEAP1-NFE2L2 pathway R-HSA-9755511
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI2 by the proteasome R-HSA-5610783
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
Infectious disease R-HSA-5663205
Mitotic Metaphase and Anaphase R-HSA-2555396
DNA Replication Pre-Initiation R-HSA-69002
Class I MHC mediated antigen processing & presentation R-HSA-983169
Gene expression (Transcription) R-HSA-74160
Regulation of Apoptosis R-HSA-169911
Cellular response to chemical stress R-HSA-9711123
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Asymmetric localization of PCP proteins R-HSA-4608870
Neutrophil degranulation R-HSA-6798695
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ER-Phagosome pathway R-HSA-1236974
Signal Transduction R-HSA-162582
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by ROBO receptors R-HSA-376176
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RNA Polymerase II Transcription R-HSA-73857
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
TCR signaling R-HSA-202403
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX1 R-HSA-8878171
Intracellular signaling by second messengers R-HSA-9006925
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of proteins R-HSA-392499
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX3 expression and activity R-HSA-8941858
p53-Dependent G1 DNA Damage Response R-HSA-69563
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Independent DNA Damage Response R-HSA-69610
G1/S DNA Damage Checkpoints R-HSA-69615
Deubiquitination R-HSA-5688426
M Phase R-HSA-68886
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
Generic Transcription Pathway R-HSA-212436
Downstream TCR signaling R-HSA-202424
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Vpu mediated degradation of CD4 R-HSA-180534
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'off' state R-HSA-5610787
Nervous system development R-HSA-9675108
Cellular responses to stimuli R-HSA-8953897
Hedgehog ligand biogenesis R-HSA-5358346
Interleukin-1 signaling R-HSA-9020702
Separation of Sister Chromatids R-HSA-2467813
MAPK1/MAPK3 signaling R-HSA-5684996
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of GLI1 by the proteasome R-HSA-5610780
Mitotic G2-G2/M phases R-HSA-453274
UCH proteinases R-HSA-5689603
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of RNA R-HSA-8953854
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Stabilization of p53 R-HSA-69541
Regulation of RUNX2 expression and activity R-HSA-8939902
Programmed Cell Death R-HSA-5357801
Cell Cycle R-HSA-1640170
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cytokine Signaling in Immune system R-HSA-1280215
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
G2/M Transition R-HSA-69275
Disease R-HSA-1643685
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1/S Transition R-HSA-69206
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC-family proteins mediated transport R-HSA-382556
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic G1 phase and G1/S transition R-HSA-453279
Ub-specific processing proteases R-HSA-5689880
Disorders of transmembrane transporters R-HSA-5619115
Signaling by WNT R-HSA-195721
DNA Replication R-HSA-69306
ABC transporter disorders R-HSA-5619084
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to hypoxia R-HSA-1234174
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
Synthesis of DNA R-HSA-69239
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PCP/CE pathway R-HSA-4086400
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Interleukin-1 family signaling R-HSA-446652
Disorders of transmembrane transporters R-HSA-5619115
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
Mitotic Anaphase R-HSA-68882
Hh mutants are degraded by ERAD R-HSA-5362768
Adaptive Immune System R-HSA-1280218
MAPK6/MAPK4 signaling R-HSA-5687128
Asymmetric localization of PCP proteins R-HSA-4608870
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of AXIN R-HSA-4641257
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Defective CFTR causes cystic fibrosis R-HSA-5678895
HIV Infection R-HSA-162906
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
DNA Replication R-HSA-69306
Cellular responses to stimuli R-HSA-8953897
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of polyamines R-HSA-351202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
ABC-family proteins mediated transport R-HSA-382556
Activation of NF-kappaB in B cells R-HSA-1169091
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Developmental Biology R-HSA-1266738
Deubiquitination R-HSA-5688426
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by ROBO receptors R-HSA-376176
Separation of Sister Chromatids R-HSA-2467813
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by NOTCH R-HSA-157118
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Programmed Cell Death R-HSA-5357801
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
Class I MHC mediated antigen processing & presentation R-HSA-983169
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RUNX3 expression and activity R-HSA-8941858
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 signaling R-HSA-9020702
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated NF-kB activation R-HSA-2871837
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Generic Transcription Pathway R-HSA-212436
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Signaling by Interleukins R-HSA-449147
MAPK family signaling cascades R-HSA-5683057
Degradation of DVL R-HSA-4641258
Beta-catenin independent WNT signaling R-HSA-3858494
Innate Immune System R-HSA-168249
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Apoptosis R-HSA-109581
Intracellular signaling by second messengers R-HSA-9006925
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vpu mediated degradation of CD4 R-HSA-180534
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH4 R-HSA-9013694
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
RNA Polymerase II Transcription R-HSA-73857
Assembly of the pre-replicative complex R-HSA-68867
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Transition R-HSA-69275
Gene expression (Transcription) R-HSA-74160
Mitotic G1 phase and G1/S transition R-HSA-453279
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Synthesis of DNA R-HSA-69239
Cellular response to chemical stress R-HSA-9711123
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Axon guidance R-HSA-422475
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of Apoptosis R-HSA-169911
Immune System R-HSA-168256
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC transporter disorders R-HSA-5619084
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by WNT R-HSA-195721
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Hedgehog R-HSA-5358351
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Neddylation R-HSA-8951664
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Orc1 removal from chromatin R-HSA-68949
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
Stabilization of p53 R-HSA-69541
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
PIP3 activates AKT signaling R-HSA-1257604
G1/S DNA Damage Checkpoints R-HSA-69615
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog ligand biogenesis R-HSA-5358346
PCP/CE pathway R-HSA-4086400
Neutrophil degranulation R-HSA-6798695
Hedgehog 'on' state R-HSA-5632684
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Disease R-HSA-1643685
PTEN Regulation R-HSA-6807070
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S Transition R-HSA-69206
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of amino acids and derivatives R-HSA-71291
UCH proteinases R-HSA-5689603
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Switching of origins to a post-replicative state R-HSA-69052
Downstream TCR signaling R-HSA-202424
Cell Cycle Checkpoints R-HSA-69620
Post-translational protein modification R-HSA-597592
M Phase R-HSA-68886
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle R-HSA-1640170
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Neddylation R-HSA-8951664
Switching of origins to a post-replicative state R-HSA-69052
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle Checkpoints R-HSA-69620
ABC-family proteins mediated transport R-HSA-382556
Neutrophil degranulation R-HSA-6798695
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hh mutants are degraded by ERAD R-HSA-5362768
HIV Infection R-HSA-162906
Hedgehog 'on' state R-HSA-5632684
Mitotic G2-G2/M phases R-HSA-453274
Degradation of beta-catenin by the destruction complex R-HSA-195253
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 signaling R-HSA-9020702
Degradation of AXIN R-HSA-4641257
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of GLI2 by the proteasome R-HSA-5610783
Downstream TCR signaling R-HSA-202424
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle R-HSA-1640170
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
DNA Replication R-HSA-69306
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'off' state R-HSA-5610787
Regulation of Apoptosis R-HSA-169911
Generic Transcription Pathway R-HSA-212436
Programmed Cell Death R-HSA-5357801
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to chemical stress R-HSA-9711123
Intracellular signaling by second messengers R-HSA-9006925
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
Signal Transduction R-HSA-162582
Regulation of expression of SLITs and ROBOs R-HSA-9010553
UCH proteinases R-HSA-5689603
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Adaptive Immune System R-HSA-1280218
PTEN Regulation R-HSA-6807070
Degradation of GLI1 by the proteasome R-HSA-5610780
M Phase R-HSA-68886
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX3 R-HSA-8878159
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Disease R-HSA-1643685
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic Metaphase and Anaphase R-HSA-2555396
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of mitotic cell cycle R-HSA-453276
p53-Independent DNA Damage Response R-HSA-69610
Nervous system development R-HSA-9675108
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TCR signaling R-HSA-202403
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ER-Phagosome pathway R-HSA-1236974
Orc1 removal from chromatin R-HSA-68949
Cytokine Signaling in Immune system R-HSA-1280215
MAPK family signaling cascades R-HSA-5683057
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Nuclear events mediated by NFE2L2 R-HSA-9759194
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ub-specific processing proteases R-HSA-5689880
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Interleukins R-HSA-449147
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Developmental Biology R-HSA-1266738
Immune System R-HSA-168256
Disorders of transmembrane transporters R-HSA-5619115
Cyclin E associated events during G1/S transition R-HSA-69202
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic Anaphase R-HSA-68882
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants abrogate ligand secretion R-HSA-5387390
Deubiquitination R-HSA-5688426
PIP3 activates AKT signaling R-HSA-1257604
Host Interactions of HIV factors R-HSA-162909
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC transporter disorders R-HSA-5619084
Signaling by WNT R-HSA-195721
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX2 expression and activity R-HSA-8939902
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RAS by GAPs R-HSA-5658442
Innate Immune System R-HSA-168249
CLEC7A (Dectin-1) signaling R-HSA-5607764
G2/M Checkpoints R-HSA-69481
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by ROBO receptors R-HSA-376176
Signaling by NOTCH4 R-HSA-9013694
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
S Phase R-HSA-69242
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Post-translational protein modification R-HSA-597592
Synthesis of DNA R-HSA-69239
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
Cellular responses to stress R-HSA-2262752
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular responses to stimuli R-HSA-8953897
G2/M Transition R-HSA-69275
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Asymmetric localization of PCP proteins R-HSA-4608870
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of polyamines R-HSA-351202
Transport of small molecules R-HSA-382551
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S Transition R-HSA-69206
Gene expression (Transcription) R-HSA-74160
Interleukin-1 family signaling R-HSA-446652
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Assembly of the pre-replicative complex R-HSA-68867
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RNA Polymerase II Transcription R-HSA-73857
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Axon guidance R-HSA-422475
Apoptosis R-HSA-109581
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of RNA R-HSA-8953854
Metabolism of proteins R-HSA-392499
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX3 expression and activity R-HSA-8941858
Programmed Cell Death R-HSA-5357801
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of AXIN R-HSA-4641257
Axon guidance R-HSA-422475
Hedgehog 'on' state R-HSA-5632684
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of RUNX2 expression and activity R-HSA-8939902
Generic Transcription Pathway R-HSA-212436
Downstream TCR signaling R-HSA-202424
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by Hedgehog R-HSA-5358351
p53-Independent DNA Damage Response R-HSA-69610
Gene expression (Transcription) R-HSA-74160
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH4 R-HSA-9013694
ER-Phagosome pathway R-HSA-1236974
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI1 by the proteasome R-HSA-5610780
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
FCERI mediated NF-kB activation R-HSA-2871837
Class I MHC mediated antigen processing & presentation R-HSA-983169
Assembly of the pre-replicative complex R-HSA-68867
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Disorders of transmembrane transporters R-HSA-5619115
Negative regulation of NOTCH4 signaling R-HSA-9604323
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Adaptive Immune System R-HSA-1280218
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Activation of NF-kappaB in B cells R-HSA-1169091
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Post-translational protein modification R-HSA-597592
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Nuclear events mediated by NFE2L2 R-HSA-9759194
DNA Replication R-HSA-69306
Infectious disease R-HSA-5663205
HIV Infection R-HSA-162906
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX1 R-HSA-8878171
C-type lectin receptors (CLRs) R-HSA-5621481
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle, Mitotic R-HSA-69278
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'off' state R-HSA-5610787
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of DVL R-HSA-4641258
Signaling by WNT R-HSA-195721
Ub-specific processing proteases R-HSA-5689880
Neddylation R-HSA-8951664
Apoptosis R-HSA-109581
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
ABC transporter disorders R-HSA-5619084
Interleukin-1 signaling R-HSA-9020702
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Transition R-HSA-69275
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stimuli R-HSA-8953897
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
ABC-family proteins mediated transport R-HSA-382556
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by Interleukins R-HSA-449147
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
TCF dependent signaling in response to WNT R-HSA-201681
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Developmental Biology R-HSA-1266738
G2/M Checkpoints R-HSA-69481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RAS by GAPs R-HSA-5658442
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle R-HSA-1640170
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle Checkpoints R-HSA-69620
Neutrophil degranulation R-HSA-6798695
Metabolism R-HSA-1430728
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by ROBO receptors R-HSA-376176
Antigen processing-Cross presentation R-HSA-1236975
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
M Phase R-HSA-68886
Intracellular signaling by second messengers R-HSA-9006925
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Regulation of Apoptosis R-HSA-169911
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Anaphase R-HSA-68882
Regulation of PTEN stability and activity R-HSA-8948751
Switching of origins to a post-replicative state R-HSA-69052
Immune System R-HSA-168256
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
TCR signaling R-HSA-202403
Synthesis of DNA R-HSA-69239
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic Metaphase and Anaphase R-HSA-2555396
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX3 R-HSA-8878159
Host Interactions of HIV factors R-HSA-162909
Disease R-HSA-1643685
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vpu mediated degradation of CD4 R-HSA-180534
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nervous system development R-HSA-9675108
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G1/S Transition R-HSA-69206
Metabolism of polyamines R-HSA-351202
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of RNA R-HSA-8953854
Signaling by WNT R-HSA-195721
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of GLI2 by the proteasome R-HSA-5610783
Nervous system development R-HSA-9675108
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of amino acids and derivatives R-HSA-71291
TCR signaling R-HSA-202403
Synthesis of DNA R-HSA-69239
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
MAPK family signaling cascades R-HSA-5683057
Degradation of DVL R-HSA-4641258
Adaptive Immune System R-HSA-1280218
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
FCERI mediated NF-kB activation R-HSA-2871837
Activation of NF-kappaB in B cells R-HSA-1169091
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Axon guidance R-HSA-422475
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle, Mitotic R-HSA-69278
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Innate Immune System R-HSA-168249
Regulation of Apoptosis R-HSA-169911
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX3 R-HSA-8878159
Intracellular signaling by second messengers R-HSA-9006925
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of PTEN stability and activity R-HSA-8948751
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
Transport of small molecules R-HSA-382551
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
Deubiquitination R-HSA-5688426
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of RUNX2 expression and activity R-HSA-8939902
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Switching of origins to a post-replicative state R-HSA-69052
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
Separation of Sister Chromatids R-HSA-2467813
Defective CFTR causes cystic fibrosis R-HSA-5678895
Class I MHC mediated antigen processing & presentation R-HSA-983169
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Signaling by Interleukins R-HSA-449147
Signaling by ROBO receptors R-HSA-376176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PCP/CE pathway R-HSA-4086400
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog 'on' state R-HSA-5632684
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Neddylation R-HSA-8951664
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Gene expression (Transcription) R-HSA-74160
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
Ub-specific processing proteases R-HSA-5689880
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
HIV Infection R-HSA-162906
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Dependent G1 DNA Damage Response R-HSA-69563
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Neutrophil degranulation R-HSA-6798695
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Vif-mediated degradation of APOBEC3G R-HSA-180585
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent DNA Damage Response R-HSA-69610
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Cell Cycle Checkpoints R-HSA-69620
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Generic Transcription Pathway R-HSA-212436
Mitotic Metaphase and Anaphase R-HSA-2555396
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stimuli R-HSA-8953897
C-type lectin receptors (CLRs) R-HSA-5621481
S Phase R-HSA-69242
M Phase R-HSA-68886
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Mitotic Anaphase R-HSA-68882
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to hypoxia R-HSA-1234174
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
G2/M Checkpoints R-HSA-69481
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Cellular response to chemical stress R-HSA-9711123
Disease R-HSA-1643685
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic G1 phase and G1/S transition R-HSA-453279
Antigen processing-Cross presentation R-HSA-1236975
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
Vpu mediated degradation of CD4 R-HSA-180534
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of AXIN R-HSA-4641257
Metabolism R-HSA-1430728
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Generic Transcription Pathway R-HSA-212436
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle R-HSA-1640170
C-type lectin receptors (CLRs) R-HSA-5621481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog ligand biogenesis R-HSA-5358346
Apoptosis R-HSA-109581
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of PTEN stability and activity R-HSA-8948751
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Stabilization of p53 R-HSA-69541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ub-specific processing proteases R-HSA-5689880
G2/M Checkpoints R-HSA-69481
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by Hedgehog R-HSA-5358351
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cellular response to hypoxia R-HSA-1234174
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by NOTCH4 R-HSA-9013694
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
G2/M Transition R-HSA-69275
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC-family proteins mediated transport R-HSA-382556
Immune System R-HSA-168256
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
NIK-->noncanonical NF-kB signaling R-HSA-5676590
DNA Replication Pre-Initiation R-HSA-69002
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
S Phase R-HSA-69242
Transport of small molecules R-HSA-382551
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Deubiquitination R-HSA-5688426
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
Neddylation R-HSA-8951664
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stress R-HSA-2262752
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PTEN Regulation R-HSA-6807070
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle Checkpoints R-HSA-69620
Beta-catenin independent WNT signaling R-HSA-3858494
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Cyclin E associated events during G1/S transition R-HSA-69202
Axon guidance R-HSA-422475
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of Apoptosis R-HSA-169911
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of RNA R-HSA-8953854
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic Anaphase R-HSA-68882
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of polyamines R-HSA-351202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
HIV Infection R-HSA-162906
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Independent DNA Damage Response R-HSA-69610
PCP/CE pathway R-HSA-4086400
Nervous system development R-HSA-9675108
TCF dependent signaling in response to WNT R-HSA-201681
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Synthesis of DNA R-HSA-69239
Interleukin-1 family signaling R-HSA-446652
Signaling by ROBO receptors R-HSA-376176
M Phase R-HSA-68886
Hh mutants are degraded by ERAD R-HSA-5362768
Assembly of the pre-replicative complex R-HSA-68867
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
ABC transporter disorders R-HSA-5619084
Hedgehog 'off' state R-HSA-5610787
PIP3 activates AKT signaling R-HSA-1257604
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle, Mitotic R-HSA-69278
Adaptive Immune System R-HSA-1280218
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Cellular responses to stimuli R-HSA-8953897
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Dependent G1 DNA Damage Response R-HSA-69563
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Neutrophil degranulation R-HSA-6798695
Orc1 removal from chromatin R-HSA-68949
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hh mutants abrogate ligand secretion R-HSA-5387390
Signal Transduction R-HSA-162582
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication R-HSA-69306
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK6/MAPK4 signaling R-HSA-5687128
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI1 by the proteasome R-HSA-5610780
MAPK family signaling cascades R-HSA-5683057
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ub-specific processing proteases R-HSA-5689880
M Phase R-HSA-68886
Transcriptional regulation by RUNX3 R-HSA-8878159
Neddylation R-HSA-8951664
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of AXIN R-HSA-4641257
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream TCR signaling R-HSA-202424
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by ROBO receptors R-HSA-376176
Metabolism of proteins R-HSA-392499
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic Anaphase R-HSA-68882
Hh mutants are degraded by ERAD R-HSA-5362768
ABC transporter disorders R-HSA-5619084
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by WNT R-HSA-195721
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing-Cross presentation R-HSA-1236975
PTEN Regulation R-HSA-6807070
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of DVL R-HSA-4641258
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cell Cycle, Mitotic R-HSA-69278
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by NOTCH R-HSA-157118
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
p53-Independent DNA Damage Response R-HSA-69610
Cyclin E associated events during G1/S transition R-HSA-69202
ER-Phagosome pathway R-HSA-1236974
Neutrophil degranulation R-HSA-6798695
KEAP1-NFE2L2 pathway R-HSA-9755511
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G2/M Checkpoints R-HSA-69481
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of amino acids and derivatives R-HSA-71291
TCF dependent signaling in response to WNT R-HSA-201681
TCR signaling R-HSA-202403
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
Stabilization of p53 R-HSA-69541
PCP/CE pathway R-HSA-4086400
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
Orc1 removal from chromatin R-HSA-68949
Gene expression (Transcription) R-HSA-74160
Adaptive Immune System R-HSA-1280218
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Interleukin-1 signaling R-HSA-9020702
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G2-G2/M phases R-HSA-453274
UCH proteinases R-HSA-5689603
Innate Immune System R-HSA-168249
Separation of Sister Chromatids R-HSA-2467813
S Phase R-HSA-69242
Beta-catenin independent WNT signaling R-HSA-3858494
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Host Interactions of HIV factors R-HSA-162909
Transport of small molecules R-HSA-382551
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Vif-mediated degradation of APOBEC3G R-HSA-180585
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of beta-catenin by the destruction complex R-HSA-195253
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
RNA Polymerase II Transcription R-HSA-73857
Cellular response to hypoxia R-HSA-1234174
Assembly of the pre-replicative complex R-HSA-68867
Post-translational protein modification R-HSA-597592
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular response to chemical stress R-HSA-9711123
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stimuli R-HSA-8953897
Signaling by Interleukins R-HSA-449147
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK6/MAPK4 signaling R-HSA-5687128
Disease R-HSA-1643685
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by Hedgehog R-HSA-5358351
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle R-HSA-1640170
Deubiquitination R-HSA-5688426
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Axon guidance R-HSA-422475
ABC-family proteins mediated transport R-HSA-382556
Metabolism of RNA R-HSA-8953854
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Interleukin-1 family signaling R-HSA-446652
Hedgehog 'off' state R-HSA-5610787
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stress R-HSA-2262752
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
DNA Replication R-HSA-69306
Nuclear events mediated by NFE2L2 R-HSA-9759194
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Disorders of transmembrane transporters R-HSA-5619115
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G1/S Transition R-HSA-69206
Regulation of mitotic cell cycle R-HSA-453276
Regulation of RUNX3 expression and activity R-HSA-8941858
HIV Infection R-HSA-162906
Immune System R-HSA-168256
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism R-HSA-1430728
Orc1 removal from chromatin R-HSA-68949
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX1 R-HSA-8878171
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
Mitotic Metaphase and Anaphase R-HSA-2555396
Class I MHC mediated antigen processing & presentation R-HSA-983169
Stabilization of p53 R-HSA-69541
Synthesis of DNA R-HSA-69239
Apoptosis R-HSA-109581
Assembly of the pre-replicative complex R-HSA-68867
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic Anaphase R-HSA-68882
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle, Mitotic R-HSA-69278
Cyclin E associated events during G1/S transition R-HSA-69202
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing-Cross presentation R-HSA-1236975
Metabolism R-HSA-1430728
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX2 expression and activity R-HSA-8939902
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
Nervous system development R-HSA-9675108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle Checkpoints R-HSA-69620
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'on' state R-HSA-5632684
Neddylation R-HSA-8951664
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G1 phase and G1/S transition R-HSA-453279
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Infectious disease R-HSA-5663205
Programmed Cell Death R-HSA-5357801
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Disease R-HSA-1643685
Hedgehog 'off' state R-HSA-5610787
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PCP/CE pathway R-HSA-4086400
UCH proteinases R-HSA-5689603
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transcriptional regulation by RUNX2 R-HSA-8878166
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of DVL R-HSA-4641258
Degradation of GLI2 by the proteasome R-HSA-5610783
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G2/M Transition R-HSA-69275
Generic Transcription Pathway R-HSA-212436
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream TCR signaling R-HSA-202424
MAPK family signaling cascades R-HSA-5683057
Signaling by ROBO receptors R-HSA-376176
Separation of Sister Chromatids R-HSA-2467813
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
DNA Replication R-HSA-69306
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
S Phase R-HSA-69242
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Gene expression (Transcription) R-HSA-74160
Degradation of AXIN R-HSA-4641257
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by NOTCH R-HSA-157118
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stress R-HSA-2262752
ER-Phagosome pathway R-HSA-1236974
TCR signaling R-HSA-202403
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Axon guidance R-HSA-422475
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of RNA R-HSA-8953854
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
Cell Cycle R-HSA-1640170
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of beta-catenin by the destruction complex R-HSA-195253
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Interleukin-1 signaling R-HSA-9020702
HIV Infection R-HSA-162906
Cellular responses to stimuli R-HSA-8953897
Hedgehog ligand biogenesis R-HSA-5358346
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of PTEN stability and activity R-HSA-8948751
ABC transporter disorders R-HSA-5619084
Intracellular signaling by second messengers R-HSA-9006925
PTEN Regulation R-HSA-6807070
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Host Interactions of HIV factors R-HSA-162909
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neutrophil degranulation R-HSA-6798695
Transcriptional regulation by RUNX3 R-HSA-8878159
Signal Transduction R-HSA-162582
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of polyamines R-HSA-351202
Metabolism of proteins R-HSA-392499
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Adaptive Immune System R-HSA-1280218
Deubiquitination R-HSA-5688426
G1/S DNA Damage Checkpoints R-HSA-69615
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1 DNA Damage Response R-HSA-69563
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH4 R-HSA-9013694
Cytokine Signaling in Immune system R-HSA-1280215
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Cellular responses to stress R-HSA-2262752
Neddylation R-HSA-8951664
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Class I MHC mediated antigen processing & presentation R-HSA-983169
TCR signaling R-HSA-202403
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by ROBO receptors R-HSA-376176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
Hedgehog 'on' state R-HSA-5632684
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by NOTCH R-HSA-157118
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Synthesis of DNA R-HSA-69239
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Neutrophil degranulation R-HSA-6798695
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
Adaptive Immune System R-HSA-1280218
Signaling by the B Cell Receptor (BCR) R-HSA-983705
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Degradation of GLI1 by the proteasome R-HSA-5610780
ABC-family proteins mediated transport R-HSA-382556
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Host Interactions of HIV factors R-HSA-162909
FCERI mediated NF-kB activation R-HSA-2871837
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
Developmental Biology R-HSA-1266738
Metabolism of RNA R-HSA-8953854
UCH proteinases R-HSA-5689603
Cytokine Signaling in Immune system R-HSA-1280215
Vpu mediated degradation of CD4 R-HSA-180534
RNA Polymerase II Transcription R-HSA-73857
Signaling by NOTCH4 R-HSA-9013694
Innate Immune System R-HSA-168249
PIP3 activates AKT signaling R-HSA-1257604
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Gene expression (Transcription) R-HSA-74160
Transport of small molecules R-HSA-382551
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle Checkpoints R-HSA-69620
Hh mutants are degraded by ERAD R-HSA-5362768
M Phase R-HSA-68886
Interleukin-1 family signaling R-HSA-446652
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK family signaling cascades R-HSA-5683057
PCP/CE pathway R-HSA-4086400
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of DVL R-HSA-4641258
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of polyamines R-HSA-351202
G2/M Checkpoints R-HSA-69481
C-type lectin receptors (CLRs) R-HSA-5621481
ABC transporter disorders R-HSA-5619084
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ub-specific processing proteases R-HSA-5689880
Hedgehog 'off' state R-HSA-5610787
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RAS by GAPs R-HSA-5658442
Stabilization of p53 R-HSA-69541
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Independent DNA Damage Response R-HSA-69610
Beta-catenin independent WNT signaling R-HSA-3858494
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Immune System R-HSA-168256
TCF dependent signaling in response to WNT R-HSA-201681
Cellular response to chemical stress R-HSA-9711123
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Axon guidance R-HSA-422475
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic Anaphase R-HSA-68882
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
Cell Cycle R-HSA-1640170
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transcriptional regulation by RUNX3 R-HSA-8878159
Generic Transcription Pathway R-HSA-212436
Activation of NF-kappaB in B cells R-HSA-1169091
S Phase R-HSA-69242
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Programmed Cell Death R-HSA-5357801
Intracellular signaling by second messengers R-HSA-9006925
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
Nervous system development R-HSA-9675108
Downstream TCR signaling R-HSA-202424
Post-translational protein modification R-HSA-597592
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism R-HSA-1430728
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
HIV Infection R-HSA-162906
Cellular response to hypoxia R-HSA-1234174
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
KEAP1-NFE2L2 pathway R-HSA-9755511
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vif-mediated degradation of APOBEC3G R-HSA-180585
Assembly of the pre-replicative complex R-HSA-68867
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hedgehog ligand biogenesis R-HSA-5358346
G1/S Transition R-HSA-69206
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of PTEN stability and activity R-HSA-8948751
PTEN Regulation R-HSA-6807070
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by WNT R-HSA-195721
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent G1/S DNA damage checkpoint R-HSA-69613

Expression Atlas ENSG00000108671
NCBI gene (formerly Entrezgene) 5717
GeneCards 9556
HGNC Symbol HGNC:9556
MIM gene 604449
UniProtKB Gene Name O00231
WikiGene 5717
Gene: PSMD1
Ensembl ID : ENSG00000173692
Description: proteasome 26S subunit, non-ATPase 1
Gene Synonyms: P112,RPN2,S1
5 APIs:
211 Possible Orthologues:

Degradation of DVL R-HSA-4641258
Separation of Sister Chromatids R-HSA-2467813
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog ligand biogenesis R-HSA-5358346
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
Hedgehog 'off' state R-HSA-5610787
Metabolism R-HSA-1430728
MAPK family signaling cascades R-HSA-5683057
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
S Phase R-HSA-69242
Metabolism of proteins R-HSA-392499
PCP/CE pathway R-HSA-4086400
PTEN Regulation R-HSA-6807070
Transport of small molecules R-HSA-382551
Immune System R-HSA-168256
Programmed Cell Death R-HSA-5357801
Activation of NF-kappaB in B cells R-HSA-1169091
Stabilization of p53 R-HSA-69541
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'on' state R-HSA-5632684
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-1 signaling R-HSA-9020702
Assembly of the pre-replicative complex R-HSA-68867
Signaling by ROBO receptors R-HSA-376176
Nuclear events mediated by NFE2L2 R-HSA-9759194
ABC-family proteins mediated transport R-HSA-382556
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of polyamines R-HSA-351202
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Interleukins R-HSA-449147
M Phase R-HSA-68886
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Vpu mediated degradation of CD4 R-HSA-180534
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
Downstream TCR signaling R-HSA-202424
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of mitotic cell cycle R-HSA-453276
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S Transition R-HSA-69206
Neutrophil degranulation R-HSA-6798695
TCF dependent signaling in response to WNT R-HSA-201681
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
Orc1 removal from chromatin R-HSA-68949
MAPK1/MAPK3 signaling R-HSA-5684996
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ER-Phagosome pathway R-HSA-1236974
Cellular responses to stress R-HSA-2262752
MAPK6/MAPK4 signaling R-HSA-5687128
Disease R-HSA-1643685
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent DNA Damage Response R-HSA-69610
PIP3 activates AKT signaling R-HSA-1257604
Cellular response to hypoxia R-HSA-1234174
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Axon guidance R-HSA-422475
Degradation of AXIN R-HSA-4641257
Signaling by NOTCH R-HSA-157118
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of Apoptosis R-HSA-169911
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of RNA R-HSA-8953854
Switching of origins to a post-replicative state R-HSA-69052
Gene expression (Transcription) R-HSA-74160
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
CLEC7A (Dectin-1) signaling R-HSA-5607764
Synthesis of DNA R-HSA-69239
DNA Replication R-HSA-69306
TCR signaling R-HSA-202403
Regulation of RAS by GAPs R-HSA-5658442
Interleukin-1 family signaling R-HSA-446652
G2/M Transition R-HSA-69275
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Class I MHC mediated antigen processing & presentation R-HSA-983169
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Antigen processing-Cross presentation R-HSA-1236975
C-type lectin receptors (CLRs) R-HSA-5621481
Cytokine Signaling in Immune system R-HSA-1280215
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of DVL R-HSA-4641258
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
Neddylation R-HSA-8951664
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX3 expression and activity R-HSA-8941858
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Infectious disease R-HSA-5663205
Signaling by Hedgehog R-HSA-5358351
Mitotic G2-G2/M phases R-HSA-453274
Cellular response to chemical stress R-HSA-9711123
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
HIV Infection R-HSA-162906
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by WNT R-HSA-195721
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Host Interactions of HIV factors R-HSA-162909
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Innate Immune System R-HSA-168249
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX3 R-HSA-8878159
Ub-specific processing proteases R-HSA-5689880
Mitotic G1 phase and G1/S transition R-HSA-453279
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
NIK-->noncanonical NF-kB signaling R-HSA-5676590
FCERI mediated NF-kB activation R-HSA-2871837
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by Interleukins R-HSA-449147
Disease R-HSA-1643685
Degradation of GLI1 by the proteasome R-HSA-5610780
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
DNA Replication R-HSA-69306
UCH proteinases R-HSA-5689603
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'off' state R-HSA-5610787
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G2-G2/M phases R-HSA-453274
Antigen processing-Cross presentation R-HSA-1236975
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Neutrophil degranulation R-HSA-6798695
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular response to chemical stress R-HSA-9711123
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cell Cycle Checkpoints R-HSA-69620
FCERI mediated NF-kB activation R-HSA-2871837
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Separation of Sister Chromatids R-HSA-2467813
Generic Transcription Pathway R-HSA-212436
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by WNT R-HSA-195721
Stabilization of p53 R-HSA-69541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Host Interactions of HIV factors R-HSA-162909
Vif-mediated degradation of APOBEC3G R-HSA-180585
Downstream TCR signaling R-HSA-202424
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX3 R-HSA-8878159
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
ABC-family proteins mediated transport R-HSA-382556
ABC transporter disorders R-HSA-5619084
MAPK6/MAPK4 signaling R-HSA-5687128
Disorders of transmembrane transporters R-HSA-5619115
Signal Transduction R-HSA-162582
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stimuli R-HSA-8953897
HIV Infection R-HSA-162906
Intracellular signaling by second messengers R-HSA-9006925
Degradation of AXIN R-HSA-4641257
Signaling by NOTCH R-HSA-157118
Degradation of DVL R-HSA-4641258
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stress R-HSA-2262752
Infectious disease R-HSA-5663205
Deubiquitination R-HSA-5688426
Beta-catenin independent WNT signaling R-HSA-3858494
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Programmed Cell Death R-HSA-5357801
Metabolism of amino acids and derivatives R-HSA-71291
Innate Immune System R-HSA-168249
Signaling by Hedgehog R-HSA-5358351
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S DNA Damage Checkpoints R-HSA-69615
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Nervous system development R-HSA-9675108
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of RNA R-HSA-8953854
Regulation of RAS by GAPs R-HSA-5658442
Switching of origins to a post-replicative state R-HSA-69052
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH4 R-HSA-9013694
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of Apoptosis R-HSA-169911
Mitotic Metaphase and Anaphase R-HSA-2555396
PTEN Regulation R-HSA-6807070
Regulation of RUNX2 expression and activity R-HSA-8939902
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
C-type lectin receptors (CLRs) R-HSA-5621481
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TCR signaling R-HSA-202403
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Adaptive Immune System R-HSA-1280218
Interleukin-1 family signaling R-HSA-446652
Cell Cycle, Mitotic R-HSA-69278
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Asymmetric localization of PCP proteins R-HSA-4608870
KEAP1-NFE2L2 pathway R-HSA-9755511
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Synthesis of DNA R-HSA-69239
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent DNA Damage Response R-HSA-69610
Developmental Biology R-HSA-1266738
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog 'on' state R-HSA-5632684
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of PTEN stability and activity R-HSA-8948751
p53-Dependent G1 DNA Damage Response R-HSA-69563
G2/M Transition R-HSA-69275
Cytokine Signaling in Immune system R-HSA-1280215
DNA Replication Pre-Initiation R-HSA-69002
ER-Phagosome pathway R-HSA-1236974
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Anaphase R-HSA-68882
Metabolism of proteins R-HSA-392499
PCP/CE pathway R-HSA-4086400
Metabolism R-HSA-1430728
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TCF dependent signaling in response to WNT R-HSA-201681
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to hypoxia R-HSA-1234174
MAPK1/MAPK3 signaling R-HSA-5684996
Orc1 removal from chromatin R-HSA-68949
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog ligand biogenesis R-HSA-5358346
MAPK family signaling cascades R-HSA-5683057
G1/S Transition R-HSA-69206
Signaling by ROBO receptors R-HSA-376176
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stimuli R-HSA-8953897
Downstream TCR signaling R-HSA-202424
Infectious disease R-HSA-5663205
Regulation of expression of SLITs and ROBOs R-HSA-9010553
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic Anaphase R-HSA-68882
TCF dependent signaling in response to WNT R-HSA-201681
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX3 R-HSA-8878159
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent DNA Damage Response R-HSA-69610
Mitotic G2-G2/M phases R-HSA-453274
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle R-HSA-1640170
Synthesis of DNA R-HSA-69239
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of RAS by GAPs R-HSA-5658442
ER-Phagosome pathway R-HSA-1236974
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
MAPK family signaling cascades R-HSA-5683057
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog ligand biogenesis R-HSA-5358346
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Antigen processing-Cross presentation R-HSA-1236975
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 signaling R-HSA-9020702
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle, Mitotic R-HSA-69278
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
Metabolism of proteins R-HSA-392499
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Innate Immune System R-HSA-168249
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hh mutants abrogate ligand secretion R-HSA-5387390
MAPK6/MAPK4 signaling R-HSA-5687128
Hh mutants are degraded by ERAD R-HSA-5362768
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK1/MAPK3 signaling R-HSA-5684996
PIP3 activates AKT signaling R-HSA-1257604
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
HIV Infection R-HSA-162906
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
M Phase R-HSA-68886
Assembly of the pre-replicative complex R-HSA-68867
Cell Cycle Checkpoints R-HSA-69620
Hedgehog 'on' state R-HSA-5632684
Developmental Biology R-HSA-1266738
Degradation of AXIN R-HSA-4641257
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disease R-HSA-1643685
Regulation of PTEN stability and activity R-HSA-8948751
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RUNX2 expression and activity R-HSA-8939902
Switching of origins to a post-replicative state R-HSA-69052
C-type lectin receptors (CLRs) R-HSA-5621481
G2/M Checkpoints R-HSA-69481
Signaling by ROBO receptors R-HSA-376176
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Post-translational protein modification R-HSA-597592
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Dependent G1 DNA Damage Response R-HSA-69563
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH R-HSA-157118
Orc1 removal from chromatin R-HSA-68949
Degradation of beta-catenin by the destruction complex R-HSA-195253
KEAP1-NFE2L2 pathway R-HSA-9755511
ABC transporter disorders R-HSA-5619084
Regulation of mitotic cell cycle R-HSA-453276
Cellular responses to stress R-HSA-2262752
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PTEN Regulation R-HSA-6807070
Neutrophil degranulation R-HSA-6798695
Metabolism of polyamines R-HSA-351202
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ub-specific processing proteases R-HSA-5689880
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
RNA Polymerase II Transcription R-HSA-73857
PCP/CE pathway R-HSA-4086400
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'off' state R-HSA-5610787
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism R-HSA-1430728
Signaling by Hedgehog R-HSA-5358351
DNA Replication Pre-Initiation R-HSA-69002
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Beta-catenin independent WNT signaling R-HSA-3858494
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX2 R-HSA-8878166
Separation of Sister Chromatids R-HSA-2467813
Disorders of transmembrane transporters R-HSA-5619115
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
DNA Replication R-HSA-69306
Deubiquitination R-HSA-5688426
Signaling by NOTCH4 R-HSA-9013694
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
S Phase R-HSA-69242
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S DNA Damage Checkpoints R-HSA-69615
Programmed Cell Death R-HSA-5357801
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G1/S Transition R-HSA-69206
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Nervous system development R-HSA-9675108
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by WNT R-HSA-195721
Neddylation R-HSA-8951664
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transport of small molecules R-HSA-382551
Host Interactions of HIV factors R-HSA-162909
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of Apoptosis R-HSA-169911
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
M Phase R-HSA-68886
Regulation of Apoptosis R-HSA-169911
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Hedgehog R-HSA-5358351
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Host Interactions of HIV factors R-HSA-162909
Antigen processing-Cross presentation R-HSA-1236975
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Metaphase and Anaphase R-HSA-2555396
HIV Infection R-HSA-162906
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PCP/CE pathway R-HSA-4086400
ABC transporter disorders R-HSA-5619084
Hh mutants are degraded by ERAD R-HSA-5362768
ABC-family proteins mediated transport R-HSA-382556
Regulation of PTEN stability and activity R-HSA-8948751
Adaptive Immune System R-HSA-1280218
Metabolism of RNA R-HSA-8953854
Neutrophil degranulation R-HSA-6798695
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Deubiquitination R-HSA-5688426
G2/M Transition R-HSA-69275
S Phase R-HSA-69242
Degradation of AXIN R-HSA-4641257
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK6/MAPK4 signaling R-HSA-5687128
Programmed Cell Death R-HSA-5357801
Signaling by ROBO receptors R-HSA-376176
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by NOTCH4 R-HSA-9013694
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle R-HSA-1640170
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
MAPK family signaling cascades R-HSA-5683057
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH R-HSA-157118
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TCF dependent signaling in response to WNT R-HSA-201681
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular response to chemical stress R-HSA-9711123
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX2 R-HSA-8878166
Interleukin-1 signaling R-HSA-9020702
Cyclin E associated events during G1/S transition R-HSA-69202
Transport of small molecules R-HSA-382551
Nervous system development R-HSA-9675108
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
Metabolism of proteins R-HSA-392499
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Innate Immune System R-HSA-168249
Degradation of DVL R-HSA-4641258
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
Stabilization of p53 R-HSA-69541
Regulation of mitotic cell cycle R-HSA-453276
Axon guidance R-HSA-422475
p53-Independent DNA Damage Response R-HSA-69610
Cellular responses to stress R-HSA-2262752
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Post-translational protein modification R-HSA-597592
Synthesis of DNA R-HSA-69239
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Anaphase R-HSA-68882
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication R-HSA-69306
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Developmental Biology R-HSA-1266738
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hedgehog 'on' state R-HSA-5632684
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism R-HSA-1430728
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 family signaling R-HSA-446652
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RUNX3 expression and activity R-HSA-8941858
ER-Phagosome pathway R-HSA-1236974
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
Ub-specific processing proteases R-HSA-5689880
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PTEN Regulation R-HSA-6807070
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle, Mitotic R-HSA-69278
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Nuclear events mediated by NFE2L2 R-HSA-9759194
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Hedgehog 'off' state R-HSA-5610787
Metabolism of polyamines R-HSA-351202
Assembly of the pre-replicative complex R-HSA-68867
Orc1 removal from chromatin R-HSA-68949
Cellular responses to stimuli R-HSA-8953897
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of RAS by GAPs R-HSA-5658442
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Generic Transcription Pathway R-HSA-212436
p53-Dependent G1 DNA Damage Response R-HSA-69563
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Apoptosis R-HSA-109581
DNA Replication Pre-Initiation R-HSA-69002
Signaling by WNT R-HSA-195721
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PIP3 activates AKT signaling R-HSA-1257604
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
RAF/MAP kinase cascade R-HSA-5673001
KEAP1-NFE2L2 pathway R-HSA-9755511
CLEC7A (Dectin-1) signaling R-HSA-5607764
Switching of origins to a post-replicative state R-HSA-69052
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by Interleukins R-HSA-449147
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by the B Cell Receptor (BCR) R-HSA-983705
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
G1/S Transition R-HSA-69206
Degradation of beta-catenin by the destruction complex R-HSA-195253
TCR signaling R-HSA-202403
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle Checkpoints R-HSA-69620
UCH proteinases R-HSA-5689603
Metabolism of amino acids and derivatives R-HSA-71291
Disorders of transmembrane transporters R-HSA-5619115
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional regulation by RUNX3 R-HSA-8878159
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Vif-mediated degradation of APOBEC3G R-HSA-180585
Class I MHC mediated antigen processing & presentation R-HSA-983169
Asymmetric localization of PCP proteins R-HSA-4608870
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cyclin E associated events during G1/S transition R-HSA-69202
Activation of NF-kappaB in B cells R-HSA-1169091
Deubiquitination R-HSA-5688426
Degradation of GLI1 by the proteasome R-HSA-5610780
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
Signaling by NOTCH4 R-HSA-9013694
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular response to hypoxia R-HSA-1234174
Nuclear events mediated by NFE2L2 R-HSA-9759194
MAPK family signaling cascades R-HSA-5683057
Metabolism R-HSA-1430728
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
DNA Replication R-HSA-69306
Interleukin-1 signaling R-HSA-9020702
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Programmed Cell Death R-HSA-5357801
Downstream TCR signaling R-HSA-202424
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hh mutants are degraded by ERAD R-HSA-5362768
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Ub-specific processing proteases R-HSA-5689880
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transport of small molecules R-HSA-382551
Transcriptional regulation by RUNX2 R-HSA-8878166
M Phase R-HSA-68886
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of GLI2 by the proteasome R-HSA-5610783
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Stabilization of p53 R-HSA-69541
Signaling by Hedgehog R-HSA-5358351
Regulation of mitotic cell cycle R-HSA-453276
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Independent DNA Damage Response R-HSA-69610
Adaptive Immune System R-HSA-1280218
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by WNT R-HSA-195721
Switching of origins to a post-replicative state R-HSA-69052
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'off' state R-HSA-5610787
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
G1/S DNA Damage Checkpoints R-HSA-69615
RAF/MAP kinase cascade R-HSA-5673001
Post-translational protein modification R-HSA-597592
G2/M Transition R-HSA-69275
Immune System R-HSA-168256
Cellular response to chemical stress R-HSA-9711123
Axon guidance R-HSA-422475
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing-Cross presentation R-HSA-1236975
Mitotic Metaphase and Anaphase R-HSA-2555396
ABC transporter disorders R-HSA-5619084
Apoptosis R-HSA-109581
Intracellular signaling by second messengers R-HSA-9006925
ABC-family proteins mediated transport R-HSA-382556
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
S Phase R-HSA-69242
FCERI mediated NF-kB activation R-HSA-2871837
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Host Interactions of HIV factors R-HSA-162909
Degradation of AXIN R-HSA-4641257
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
ER-Phagosome pathway R-HSA-1236974
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Anaphase R-HSA-68882
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by ROBO receptors R-HSA-376176
Generic Transcription Pathway R-HSA-212436
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic G1 phase and G1/S transition R-HSA-453279
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
HIV Infection R-HSA-162906
TCR signaling R-HSA-202403
Infectious disease R-HSA-5663205
G1/S Transition R-HSA-69206
Cell Cycle Checkpoints R-HSA-69620
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of RAS by GAPs R-HSA-5658442
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by NOTCH R-HSA-157118
Synthesis of DNA R-HSA-69239
TCF dependent signaling in response to WNT R-HSA-201681
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Nervous system development R-HSA-9675108
Regulation of RUNX2 expression and activity R-HSA-8939902
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
Separation of Sister Chromatids R-HSA-2467813
Negative regulation of NOTCH4 signaling R-HSA-9604323
G2/M Checkpoints R-HSA-69481
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Neutrophil degranulation R-HSA-6798695
DNA Replication Pre-Initiation R-HSA-69002
Neddylation R-HSA-8951664
Degradation of DVL R-HSA-4641258
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of polyamines R-HSA-351202
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of beta-catenin by the destruction complex R-HSA-195253
UCH proteinases R-HSA-5689603
Signaling by Interleukins R-HSA-449147
Regulation of RUNX3 expression and activity R-HSA-8941858
Vpu mediated degradation of CD4 R-HSA-180534
Orc1 removal from chromatin R-HSA-68949
PTEN Regulation R-HSA-6807070
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stimuli R-HSA-8953897
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of expression of SLITs and ROBOs R-HSA-9010553
RNA Polymerase II Transcription R-HSA-73857
Signaling by Hedgehog R-HSA-5358351
G2/M Checkpoints R-HSA-69481
Metabolism of RNA R-HSA-8953854
Cellular responses to stress R-HSA-2262752
Signaling by Interleukins R-HSA-449147
Signaling by WNT R-HSA-195721
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Innate Immune System R-HSA-168249
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by NOTCH R-HSA-157118
Hh mutants are degraded by ERAD R-HSA-5362768
Transport of small molecules R-HSA-382551
Neddylation R-HSA-8951664
Disorders of transmembrane transporters R-HSA-5619115
Nuclear events mediated by NFE2L2 R-HSA-9759194
Infectious disease R-HSA-5663205
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular response to hypoxia R-HSA-1234174
Axon guidance R-HSA-422475
p53-Dependent G1 DNA Damage Response R-HSA-69563
Vpu mediated degradation of CD4 R-HSA-180534
S Phase R-HSA-69242
Separation of Sister Chromatids R-HSA-2467813
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication Pre-Initiation R-HSA-69002
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by ROBO receptors R-HSA-376176
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Metabolism R-HSA-1430728
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of AXIN R-HSA-4641257
Assembly of the pre-replicative complex R-HSA-68867
Hedgehog 'on' state R-HSA-5632684
Disease R-HSA-1643685
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nervous system development R-HSA-9675108
Degradation of DVL R-HSA-4641258
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle R-HSA-1640170
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Orc1 removal from chromatin R-HSA-68949
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic Anaphase R-HSA-68882
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle, Mitotic R-HSA-69278
Programmed Cell Death R-HSA-5357801
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Neutrophil degranulation R-HSA-6798695
Intracellular signaling by second messengers R-HSA-9006925
C-type lectin receptors (CLRs) R-HSA-5621481
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
PIP3 activates AKT signaling R-HSA-1257604
HIV Infection R-HSA-162906
Negative regulation of NOTCH4 signaling R-HSA-9604323
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Deubiquitination R-HSA-5688426
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
TCF dependent signaling in response to WNT R-HSA-201681
Signal Transduction R-HSA-162582
p53-Independent DNA Damage Response R-HSA-69610
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RUNX3 expression and activity R-HSA-8941858
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ABC-family proteins mediated transport R-HSA-382556
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCR signaling R-HSA-202403
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transcriptional regulation by RUNX3 R-HSA-8878159
Class I MHC mediated antigen processing & presentation R-HSA-983169
Beta-catenin independent WNT signaling R-HSA-3858494
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream TCR signaling R-HSA-202424
Hedgehog 'off' state R-HSA-5610787
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of Apoptosis R-HSA-169911
Regulation of mitotic cell cycle R-HSA-453276
Cellular responses to stimuli R-HSA-8953897
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Generic Transcription Pathway R-HSA-212436
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
RAF/MAP kinase cascade R-HSA-5673001
Apoptosis R-HSA-109581
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
M Phase R-HSA-68886
Synthesis of DNA R-HSA-69239
Interleukin-1 signaling R-HSA-9020702
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cyclin E associated events during G1/S transition R-HSA-69202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of amino acids and derivatives R-HSA-71291
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Cell Cycle Checkpoints R-HSA-69620
Asymmetric localization of PCP proteins R-HSA-4608870
Developmental Biology R-HSA-1266738
ER-Phagosome pathway R-HSA-1236974
Metabolism of proteins R-HSA-392499
Mitotic G2-G2/M phases R-HSA-453274
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog ligand biogenesis R-HSA-5358346
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Cellular response to chemical stress R-HSA-9711123
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of GLI1 by the proteasome R-HSA-5610780
Switching of origins to a post-replicative state R-HSA-69052
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Gene expression (Transcription) R-HSA-74160
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of Apoptosis R-HSA-169911
Degradation of AXIN R-HSA-4641257
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hedgehog 'on' state R-HSA-5632684
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle, Mitotic R-HSA-69278
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
Signaling by Hedgehog R-HSA-5358351
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ER-Phagosome pathway R-HSA-1236974
Cell Cycle Checkpoints R-HSA-69620
Intracellular signaling by second messengers R-HSA-9006925
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle R-HSA-1640170
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Signaling by NOTCH4 R-HSA-9013694
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of RUNX3 expression and activity R-HSA-8941858
TCF dependent signaling in response to WNT R-HSA-201681
ABC transporter disorders R-HSA-5619084
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
Synthesis of DNA R-HSA-69239
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX3 R-HSA-8878159
Neddylation R-HSA-8951664
Post-translational protein modification R-HSA-597592
Deubiquitination R-HSA-5688426
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of GLI2 by the proteasome R-HSA-5610783
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G1/S Transition R-HSA-69206
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Interleukins R-HSA-449147
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Defective CFTR causes cystic fibrosis R-HSA-5678895
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of PTEN stability and activity R-HSA-8948751
Infectious disease R-HSA-5663205
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
Ub-specific processing proteases R-HSA-5689880
Cyclin E associated events during G1/S transition R-HSA-69202
Hh mutants abrogate ligand secretion R-HSA-5387390
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog 'off' state R-HSA-5610787
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK6/MAPK4 signaling R-HSA-5687128
PTEN Regulation R-HSA-6807070
RAF/MAP kinase cascade R-HSA-5673001
Adaptive Immune System R-HSA-1280218
G2/M Checkpoints R-HSA-69481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
C-type lectin receptors (CLRs) R-HSA-5621481
Neutrophil degranulation R-HSA-6798695
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
MAPK1/MAPK3 signaling R-HSA-5684996
Programmed Cell Death R-HSA-5357801
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Beta-catenin independent WNT signaling R-HSA-3858494
p53-Independent DNA Damage Response R-HSA-69610
Disorders of transmembrane transporters R-HSA-5619115
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Activation of NF-kappaB in B cells R-HSA-1169091
Downstream TCR signaling R-HSA-202424
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Mitotic Metaphase and Anaphase R-HSA-2555396
Nervous system development R-HSA-9675108
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 signaling R-HSA-9020702
Generic Transcription Pathway R-HSA-212436
DNA Replication R-HSA-69306
Immune System R-HSA-168256
Cellular responses to stress R-HSA-2262752
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cytokine Signaling in Immune system R-HSA-1280215
Apoptosis R-HSA-109581
Metabolism of polyamines R-HSA-351202
G2/M Transition R-HSA-69275
Nuclear events mediated by NFE2L2 R-HSA-9759194
Orc1 removal from chromatin R-HSA-68949
Regulation of mitotic cell cycle R-HSA-453276
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Switching of origins to a post-replicative state R-HSA-69052
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Vpu mediated degradation of CD4 R-HSA-180534
S Phase R-HSA-69242
Degradation of DVL R-HSA-4641258
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by WNT R-HSA-195721
Regulation of RAS by GAPs R-HSA-5658442
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PCP/CE pathway R-HSA-4086400
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hh mutants are degraded by ERAD R-HSA-5362768
Transport of small molecules R-HSA-382551
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX1 R-HSA-8878171
Stabilization of p53 R-HSA-69541
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular responses to stimuli R-HSA-8953897
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
Host Interactions of HIV factors R-HSA-162909
Metabolism R-HSA-1430728
Interleukin-1 family signaling R-HSA-446652
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of RNA R-HSA-8953854
Ub-specific processing proteases R-HSA-5689880
Signaling by ROBO receptors R-HSA-376176
Metabolism of proteins R-HSA-392499
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
Hh mutants are degraded by ERAD R-HSA-5362768
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'on' state R-HSA-5632684
Metabolism R-HSA-1430728
Degradation of GLI1 by the proteasome R-HSA-5610780
PIP3 activates AKT signaling R-HSA-1257604
DNA Replication R-HSA-69306
Disease R-HSA-1643685
Metabolism of polyamines R-HSA-351202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Synthesis of DNA R-HSA-69239
Programmed Cell Death R-HSA-5357801
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stress R-HSA-2262752
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Innate Immune System R-HSA-168249
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Metaphase and Anaphase R-HSA-2555396
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of Apoptosis R-HSA-169911
Cyclin E associated events during G1/S transition R-HSA-69202
Orc1 removal from chromatin R-HSA-68949
Degradation of DVL R-HSA-4641258
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
Neddylation R-HSA-8951664
FCERI mediated NF-kB activation R-HSA-2871837
G2/M Checkpoints R-HSA-69481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Intracellular signaling by second messengers R-HSA-9006925
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK1/MAPK3 signaling R-HSA-5684996
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RAS by GAPs R-HSA-5658442
Mitotic G2-G2/M phases R-HSA-453274
Apoptosis R-HSA-109581
PCP/CE pathway R-HSA-4086400
Signaling by Hedgehog R-HSA-5358351
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stimuli R-HSA-8953897
PTEN Regulation R-HSA-6807070
Cellular response to chemical stress R-HSA-9711123
Transport of small molecules R-HSA-382551
Cell Cycle R-HSA-1640170
Class I MHC mediated antigen processing & presentation R-HSA-983169
Signaling by WNT R-HSA-195721
p53-Independent DNA Damage Response R-HSA-69610
ER-Phagosome pathway R-HSA-1236974
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream TCR signaling R-HSA-202424
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of AXIN R-HSA-4641257
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK6/MAPK4 signaling R-HSA-5687128
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Interleukin-1 signaling R-HSA-9020702
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX3 R-HSA-8878159
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Deubiquitination R-HSA-5688426
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by NOTCH4 R-HSA-9013694
Disorders of transmembrane transporters R-HSA-5619115
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Host Interactions of HIV factors R-HSA-162909
Mitotic G1 phase and G1/S transition R-HSA-453279
HIV Infection R-HSA-162906
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Adaptive Immune System R-HSA-1280218
Gene expression (Transcription) R-HSA-74160
Degradation of GLI2 by the proteasome R-HSA-5610783
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Vpu mediated degradation of CD4 R-HSA-180534
G1/S Transition R-HSA-69206
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH R-HSA-157118
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ABC-family proteins mediated transport R-HSA-382556
Nervous system development R-HSA-9675108
TCR signaling R-HSA-202403
Infectious disease R-HSA-5663205
Cell Cycle Checkpoints R-HSA-69620
Neutrophil degranulation R-HSA-6798695
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
G2/M Transition R-HSA-69275
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
DNA Replication Pre-Initiation R-HSA-69002
Vif-mediated degradation of APOBEC3G R-HSA-180585
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signal Transduction R-HSA-162582
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
UCH proteinases R-HSA-5689603
Degradation of beta-catenin by the destruction complex R-HSA-195253
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
Switching of origins to a post-replicative state R-HSA-69052
Mitotic Anaphase R-HSA-68882
Beta-catenin independent WNT signaling R-HSA-3858494
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
G2/M Checkpoints R-HSA-69481
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RNA Polymerase II Transcription R-HSA-73857
ABC transporter disorders R-HSA-5619084
Axon guidance R-HSA-422475
HIV Infection R-HSA-162906
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of Apoptosis R-HSA-169911
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
PCP/CE pathway R-HSA-4086400
Degradation of DVL R-HSA-4641258
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog 'on' state R-HSA-5632684
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
UCH proteinases R-HSA-5689603
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cytokine Signaling in Immune system R-HSA-1280215
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH R-HSA-157118
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
Infectious disease R-HSA-5663205
Nuclear events mediated by NFE2L2 R-HSA-9759194
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Deubiquitination R-HSA-5688426
ER-Phagosome pathway R-HSA-1236974
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
Cell Cycle, Mitotic R-HSA-69278
Mitotic Anaphase R-HSA-68882
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CLEC7A (Dectin-1) signaling R-HSA-5607764
Developmental Biology R-HSA-1266738
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to chemical stress R-HSA-9711123
Orc1 removal from chromatin R-HSA-68949
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle Checkpoints R-HSA-69620
FCERI mediated NF-kB activation R-HSA-2871837
p53-Dependent G1 DNA Damage Response R-HSA-69563
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic Metaphase and Anaphase R-HSA-2555396
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S Transition R-HSA-69206
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
TCF dependent signaling in response to WNT R-HSA-201681
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by WNT R-HSA-195721
Hh mutants are degraded by ERAD R-HSA-5362768
Programmed Cell Death R-HSA-5357801
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Downstream TCR signaling R-HSA-202424
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Gene expression (Transcription) R-HSA-74160
Neddylation R-HSA-8951664
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Adaptive Immune System R-HSA-1280218
Mitotic G2-G2/M phases R-HSA-453274
Synthesis of DNA R-HSA-69239
Beta-catenin independent WNT signaling R-HSA-3858494
Innate Immune System R-HSA-168249
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK family signaling cascades R-HSA-5683057
Cell Cycle R-HSA-1640170
DNA Replication Pre-Initiation R-HSA-69002
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RAS by GAPs R-HSA-5658442
Activation of NF-kappaB in B cells R-HSA-1169091
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
Metabolism of proteins R-HSA-392499
Metabolism of polyamines R-HSA-351202
Ub-specific processing proteases R-HSA-5689880
Cellular responses to stimuli R-HSA-8953897
Hedgehog ligand biogenesis R-HSA-5358346
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to hypoxia R-HSA-1234174
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Defective CFTR causes cystic fibrosis R-HSA-5678895
DNA Replication R-HSA-69306
Apoptosis R-HSA-109581
Immune System R-HSA-168256
Mitotic G1 phase and G1/S transition R-HSA-453279
S Phase R-HSA-69242
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC-family proteins mediated transport R-HSA-382556
Degradation of GLI2 by the proteasome R-HSA-5610783
Assembly of the pre-replicative complex R-HSA-68867
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of RNA R-HSA-8953854
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S DNA Damage Checkpoints R-HSA-69615
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
p53-Independent DNA Damage Response R-HSA-69610
Metabolism R-HSA-1430728
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
KEAP1-NFE2L2 pathway R-HSA-9755511
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX1 R-HSA-8878171
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX2 R-HSA-8878166
Neutrophil degranulation R-HSA-6798695
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of AXIN R-HSA-4641257
Stabilization of p53 R-HSA-69541
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'on' state R-HSA-5632684
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Asymmetric localization of PCP proteins R-HSA-4608870
Signal Transduction R-HSA-162582
UCH proteinases R-HSA-5689603
G2/M Transition R-HSA-69275
Signaling by Hedgehog R-HSA-5358351
Adaptive Immune System R-HSA-1280218
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of RNA R-HSA-8953854
Nuclear events mediated by NFE2L2 R-HSA-9759194
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
Mitotic Anaphase R-HSA-68882
Neddylation R-HSA-8951664
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
ABC transporter disorders R-HSA-5619084
Beta-catenin independent WNT signaling R-HSA-3858494
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ER-Phagosome pathway R-HSA-1236974
Neutrophil degranulation R-HSA-6798695
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
Degradation of GLI2 by the proteasome R-HSA-5610783
Mitotic G2-G2/M phases R-HSA-453274
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Degradation of DVL R-HSA-4641258
Signaling by WNT R-HSA-195721
Nervous system development R-HSA-9675108
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RAF/MAP kinase cascade R-HSA-5673001
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle Checkpoints R-HSA-69620
DNA Replication R-HSA-69306
p53-Independent DNA Damage Response R-HSA-69610
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of AXIN R-HSA-4641257
Regulation of mitotic cell cycle R-HSA-453276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cytokine Signaling in Immune system R-HSA-1280215
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by Interleukins R-HSA-449147
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of proteins R-HSA-392499
MAPK6/MAPK4 signaling R-HSA-5687128
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Deubiquitination R-HSA-5688426
Metabolism R-HSA-1430728
FCERI mediated NF-kB activation R-HSA-2871837
PIP3 activates AKT signaling R-HSA-1257604
RNA Polymerase II Transcription R-HSA-73857
Stabilization of p53 R-HSA-69541
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
G1/S Transition R-HSA-69206
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hedgehog 'off' state R-HSA-5610787
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle R-HSA-1640170
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Disorders of transmembrane transporters R-HSA-5619115
Post-translational protein modification R-HSA-597592
Metabolism of polyamines R-HSA-351202
Immune System R-HSA-168256
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Synthesis of DNA R-HSA-69239
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
M Phase R-HSA-68886
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Interleukin-1 signaling R-HSA-9020702
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
Activation of NF-kappaB in B cells R-HSA-1169091
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
MAPK family signaling cascades R-HSA-5683057
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing-Cross presentation R-HSA-1236975
Vpu mediated degradation of CD4 R-HSA-180534
Vif-mediated degradation of APOBEC3G R-HSA-180585
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle, Mitotic R-HSA-69278
Gene expression (Transcription) R-HSA-74160
Degradation of beta-catenin by the destruction complex R-HSA-195253
Orc1 removal from chromatin R-HSA-68949
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular responses to stimuli R-HSA-8953897
CLEC7A (Dectin-1) signaling R-HSA-5607764
ABC-family proteins mediated transport R-HSA-382556
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Class I MHC mediated antigen processing & presentation R-HSA-983169
Downstream TCR signaling R-HSA-202424
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
Signaling by ROBO receptors R-HSA-376176
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Infectious disease R-HSA-5663205
Intracellular signaling by second messengers R-HSA-9006925
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ub-specific processing proteases R-HSA-5689880
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of PTEN stability and activity R-HSA-8948751
PCP/CE pathway R-HSA-4086400
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Apoptosis R-HSA-109581
G2/M Checkpoints R-HSA-69481
TCF dependent signaling in response to WNT R-HSA-201681
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of Apoptosis R-HSA-169911
Synthesis of DNA R-HSA-69239
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic G1 phase and G1/S transition R-HSA-453279
Programmed Cell Death R-HSA-5357801
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Ub-specific processing proteases R-HSA-5689880
Axon guidance R-HSA-422475
Mitotic Anaphase R-HSA-68882
Switching of origins to a post-replicative state R-HSA-69052
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK1/MAPK3 signaling R-HSA-5684996
Separation of Sister Chromatids R-HSA-2467813
Generic Transcription Pathway R-HSA-212436
Stabilization of p53 R-HSA-69541
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Hedgehog R-HSA-5358351
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of PTEN stability and activity R-HSA-8948751
Assembly of the pre-replicative complex R-HSA-68867
Apoptosis R-HSA-109581
Cell Cycle R-HSA-1640170
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle, Mitotic R-HSA-69278
S Phase R-HSA-69242
Cellular response to hypoxia R-HSA-1234174
Signaling by Interleukins R-HSA-449147
Neutrophil degranulation R-HSA-6798695
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'off' state R-HSA-5610787
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
ABC transporter disorders R-HSA-5619084
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
G2/M Transition R-HSA-69275
ER-Phagosome pathway R-HSA-1236974
G1/S Transition R-HSA-69206
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of beta-catenin by the destruction complex R-HSA-195253
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular response to chemical stress R-HSA-9711123
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neddylation R-HSA-8951664
DNA Replication Pre-Initiation R-HSA-69002
Interleukin-1 signaling R-HSA-9020702
PCP/CE pathway R-HSA-4086400
ABC-family proteins mediated transport R-HSA-382556
PIP3 activates AKT signaling R-HSA-1257604
PTEN Regulation R-HSA-6807070
Degradation of AXIN R-HSA-4641257
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream TCR signaling R-HSA-202424
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'on' state R-HSA-5632684
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G2/M Checkpoints R-HSA-69481
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX2 R-HSA-8878166
Disorders of transmembrane transporters R-HSA-5619115
UCH proteinases R-HSA-5689603
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Immune System R-HSA-168256
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of RNA R-HSA-8953854
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
Signal Transduction R-HSA-162582
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by NOTCH R-HSA-157118
MAPK6/MAPK4 signaling R-HSA-5687128
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism R-HSA-1430728
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transport of small molecules R-HSA-382551
Metabolism of amino acids and derivatives R-HSA-71291
Post-translational protein modification R-HSA-597592
Orc1 removal from chromatin R-HSA-68949
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by ROBO receptors R-HSA-376176
TCR signaling R-HSA-202403
Degradation of DVL R-HSA-4641258
Signaling by NOTCH4 R-HSA-9013694
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vif-mediated degradation of APOBEC3G R-HSA-180585
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Dependent G1 DNA Damage Response R-HSA-69563
Mitotic G2-G2/M phases R-HSA-453274
Gene expression (Transcription) R-HSA-74160
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
TCF dependent signaling in response to WNT R-HSA-201681
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent DNA Damage Response R-HSA-69610
RAF/MAP kinase cascade R-HSA-5673001
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cell Cycle Checkpoints R-HSA-69620
Metabolism of proteins R-HSA-392499
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hh mutants are degraded by ERAD R-HSA-5362768
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
DNA Replication R-HSA-69306
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Deubiquitination R-HSA-5688426
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
Regulation of Apoptosis R-HSA-169911
Hedgehog ligand biogenesis R-HSA-5358346
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RAS by GAPs R-HSA-5658442
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of polyamines R-HSA-351202
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stress R-HSA-2262752

Expression Atlas ENSG00000173692
NCBI gene (formerly Entrezgene) 5707
GeneCards 9554
HGNC Symbol HGNC:9554
MIM gene 617842
UniProtKB Gene Name Q99460
WikiGene 5707
Gene: PSMD6
Ensembl ID : ENSG00000163636
Description: proteasome 26S subunit, non-ATPase 6
Gene Synonyms: KIAA0107,P44S10,RPN7,S10
5 APIs:
212 Possible Orthologues:

Cellular responses to stress R-HSA-2262752
DNA Replication R-HSA-69306
G2/M Checkpoints R-HSA-69481
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of RNA R-HSA-8953854
Beta-catenin independent WNT signaling R-HSA-3858494
G2/M Checkpoints R-HSA-69481
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent DNA Damage Response R-HSA-69610
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism R-HSA-1430728
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 signaling R-HSA-9020702
Apoptosis R-HSA-109581
Cell Cycle, Mitotic R-HSA-69278
Regulation of RAS by GAPs R-HSA-5658442
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
UCH proteinases R-HSA-5689603
ER-Phagosome pathway R-HSA-1236974
Neutrophil degranulation R-HSA-6798695
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of Apoptosis R-HSA-169911
Separation of Sister Chromatids R-HSA-2467813
Metabolism of polyamines R-HSA-351202
Hh mutants are degraded by ERAD R-HSA-5362768
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH4 R-HSA-9013694
Signaling by ROBO receptors R-HSA-376176
Post-translational protein modification R-HSA-597592
TCR signaling R-HSA-202403
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PTEN Regulation R-HSA-6807070
Degradation of beta-catenin by the destruction complex R-HSA-195253
Disorders of transmembrane transporters R-HSA-5619115
S Phase R-HSA-69242
Switching of origins to a post-replicative state R-HSA-69052
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Host Interactions of HIV factors R-HSA-162909
DNA Replication Pre-Initiation R-HSA-69002
TCF dependent signaling in response to WNT R-HSA-201681
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of DVL R-HSA-4641258
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle Checkpoints R-HSA-69620
DNA Replication R-HSA-69306
G1/S DNA Damage Checkpoints R-HSA-69615
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Activation of NF-kappaB in B cells R-HSA-1169091
Hedgehog 'off' state R-HSA-5610787
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of PTEN stability and activity R-HSA-8948751
C-type lectin receptors (CLRs) R-HSA-5621481
ABC transporter disorders R-HSA-5619084
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Orc1 removal from chromatin R-HSA-68949
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
Mitotic G1 phase and G1/S transition R-HSA-453279
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Gene expression (Transcription) R-HSA-74160
Cellular response to chemical stress R-HSA-9711123
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transport of small molecules R-HSA-382551
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Adaptive Immune System R-HSA-1280218
Developmental Biology R-HSA-1266738
PCP/CE pathway R-HSA-4086400
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic G2-G2/M phases R-HSA-453274
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
Regulation of RUNX3 expression and activity R-HSA-8941858
Infectious disease R-HSA-5663205
Degradation of AXIN R-HSA-4641257
Metabolism of proteins R-HSA-392499
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Vpu mediated degradation of CD4 R-HSA-180534
Cellular responses to stimuli R-HSA-8953897
Hedgehog ligand biogenesis R-HSA-5358346
M Phase R-HSA-68886
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle R-HSA-1640170
Defective CFTR causes cystic fibrosis R-HSA-5678895
Neddylation R-HSA-8951664
Signal Transduction R-HSA-162582
Interleukin-1 family signaling R-HSA-446652
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI2 by the proteasome R-HSA-5610783
PIP3 activates AKT signaling R-HSA-1257604
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Interleukins R-HSA-449147
Hedgehog 'on' state R-HSA-5632684
Stabilization of p53 R-HSA-69541
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Programmed Cell Death R-HSA-5357801
G2/M Transition R-HSA-69275
Asymmetric localization of PCP proteins R-HSA-4608870
Disease R-HSA-1643685
Downstream TCR signaling R-HSA-202424
Innate Immune System R-HSA-168249
CLEC7A (Dectin-1) signaling R-HSA-5607764
Ub-specific processing proteases R-HSA-5689880
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK family signaling cascades R-HSA-5683057
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Signaling by NOTCH R-HSA-157118
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX2 R-HSA-8878166
RNA Polymerase II Transcription R-HSA-73857
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Immune System R-HSA-168256
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cyclin E associated events during G1/S transition R-HSA-69202
Deubiquitination R-HSA-5688426
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX3 R-HSA-8878159
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic G2-G2/M phases R-HSA-453274
Vif-mediated degradation of APOBEC3G R-HSA-180585
PIP3 activates AKT signaling R-HSA-1257604
Assembly of the pre-replicative complex R-HSA-68867
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of Apoptosis R-HSA-169911
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
TCR signaling R-HSA-202403
Ub-specific processing proteases R-HSA-5689880
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disorders of transmembrane transporters R-HSA-5619115
Intracellular signaling by second messengers R-HSA-9006925
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 signaling R-HSA-9020702
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Degradation of GLI1 by the proteasome R-HSA-5610780
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
CLEC7A (Dectin-1) signaling R-HSA-5607764
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular responses to stress R-HSA-2262752
Metabolism R-HSA-1430728
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Neddylation R-HSA-8951664
Hedgehog ligand biogenesis R-HSA-5358346
Transport of small molecules R-HSA-382551
Signaling by NOTCH R-HSA-157118
Activation of NF-kappaB in B cells R-HSA-1169091
G2/M Checkpoints R-HSA-69481
Switching of origins to a post-replicative state R-HSA-69052
Infectious disease R-HSA-5663205
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'off' state R-HSA-5610787
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Axon guidance R-HSA-422475
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Beta-catenin independent WNT signaling R-HSA-3858494
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by WNT R-HSA-195721
Immune System R-HSA-168256
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Mitotic Anaphase R-HSA-68882
Developmental Biology R-HSA-1266738
Regulation of PTEN stability and activity R-HSA-8948751
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
Class I MHC mediated antigen processing & presentation R-HSA-983169
Separation of Sister Chromatids R-HSA-2467813
UCH proteinases R-HSA-5689603
Neutrophil degranulation R-HSA-6798695
Hedgehog 'on' state R-HSA-5632684
Signaling by ROBO receptors R-HSA-376176
ABC-family proteins mediated transport R-HSA-382556
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Signaling by Hedgehog R-HSA-5358351
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Adaptive Immune System R-HSA-1280218
PTEN Regulation R-HSA-6807070
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
TCF dependent signaling in response to WNT R-HSA-201681
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RNA Polymerase II Transcription R-HSA-73857
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK family signaling cascades R-HSA-5683057
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to hypoxia R-HSA-1234174
HIV Infection R-HSA-162906
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of RNA R-HSA-8953854
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Stabilization of p53 R-HSA-69541
G1/S DNA Damage Checkpoints R-HSA-69615
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle, Mitotic R-HSA-69278
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of GLI2 by the proteasome R-HSA-5610783
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent DNA Damage Response R-HSA-69610
PCP/CE pathway R-HSA-4086400
Innate Immune System R-HSA-168249
S Phase R-HSA-69242
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
Apoptosis R-HSA-109581
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of RUNX3 expression and activity R-HSA-8941858
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of AXIN R-HSA-4641257
Gene expression (Transcription) R-HSA-74160
Antigen processing-Cross presentation R-HSA-1236975
Cellular response to chemical stress R-HSA-9711123
Signaling by Interleukins R-HSA-449147
Post-translational protein modification R-HSA-597592
FCERI mediated NF-kB activation R-HSA-2871837
Defective CFTR causes cystic fibrosis R-HSA-5678895
RAF/MAP kinase cascade R-HSA-5673001
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Programmed Cell Death R-HSA-5357801
Metabolism of polyamines R-HSA-351202
Regulation of RAS by GAPs R-HSA-5658442
M Phase R-HSA-68886
Regulation of mitotic cell cycle R-HSA-453276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G2/M Transition R-HSA-69275
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX3 R-HSA-8878159
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Nuclear events mediated by NFE2L2 R-HSA-9759194
Host Interactions of HIV factors R-HSA-162909
Metabolism of proteins R-HSA-392499
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of Apoptosis R-HSA-169911
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
UCH proteinases R-HSA-5689603
Asymmetric localization of PCP proteins R-HSA-4608870
Neddylation R-HSA-8951664
Hedgehog 'off' state R-HSA-5610787
Antigen processing-Cross presentation R-HSA-1236975
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Signaling by NOTCH R-HSA-157118
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle Checkpoints R-HSA-69620
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of mitotic cell cycle R-HSA-453276
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transcriptional regulation by RUNX2 R-HSA-8878166
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Adaptive Immune System R-HSA-1280218
RNA Polymerase II Transcription R-HSA-73857
Deubiquitination R-HSA-5688426
Interleukin-1 signaling R-HSA-9020702
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by ROBO receptors R-HSA-376176
CLEC7A (Dectin-1) signaling R-HSA-5607764
PIP3 activates AKT signaling R-HSA-1257604
Activation of NF-kappaB in B cells R-HSA-1169091
Post-translational protein modification R-HSA-597592
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RUNX2 expression and activity R-HSA-8939902
Cytokine Signaling in Immune system R-HSA-1280215
Downstream TCR signaling R-HSA-202424
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of polyamines R-HSA-351202
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of RNA R-HSA-8953854
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by Interleukins R-HSA-449147
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of amino acids and derivatives R-HSA-71291
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle R-HSA-1640170
Signaling by WNT R-HSA-195721
Infectious disease R-HSA-5663205
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Neutrophil degranulation R-HSA-6798695
p53-Independent DNA Damage Response R-HSA-69610
Negative regulation of NOTCH4 signaling R-HSA-9604323
Mitotic Metaphase and Anaphase R-HSA-2555396
TCR signaling R-HSA-202403
Hedgehog 'on' state R-HSA-5632684
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
ABC transporter disorders R-HSA-5619084
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stress R-HSA-2262752
Regulation of PTEN stability and activity R-HSA-8948751
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Disorders of transmembrane transporters R-HSA-5619115
Developmental Biology R-HSA-1266738
MAPK6/MAPK4 signaling R-HSA-5687128
Innate Immune System R-HSA-168249
Degradation of DVL R-HSA-4641258
Transport of small molecules R-HSA-382551
FCERI mediated NF-kB activation R-HSA-2871837
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX3 R-HSA-8878159
Gene expression (Transcription) R-HSA-74160
Cellular response to chemical stress R-HSA-9711123
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Programmed Cell Death R-HSA-5357801
Metabolism R-HSA-1430728
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Interleukin-1 family signaling R-HSA-446652
Generic Transcription Pathway R-HSA-212436
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
G2/M Checkpoints R-HSA-69481
p53-Dependent G1 DNA Damage Response R-HSA-69563
Separation of Sister Chromatids R-HSA-2467813
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
TCF dependent signaling in response to WNT R-HSA-201681
ABC-family proteins mediated transport R-HSA-382556
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Host Interactions of HIV factors R-HSA-162909
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ER-Phagosome pathway R-HSA-1236974
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle, Mitotic R-HSA-69278
Orc1 removal from chromatin R-HSA-68949
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Apoptosis R-HSA-109581
PCP/CE pathway R-HSA-4086400
G1/S Transition R-HSA-69206
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Intracellular signaling by second messengers R-HSA-9006925
S Phase R-HSA-69242
Class I MHC mediated antigen processing & presentation R-HSA-983169
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G2/M Transition R-HSA-69275
Mitotic Anaphase R-HSA-68882
Regulation of RAS by GAPs R-HSA-5658442
HIV Infection R-HSA-162906
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin E associated events during G1/S transition R-HSA-69202
Stabilization of p53 R-HSA-69541
Hedgehog ligand biogenesis R-HSA-5358346
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI1 by the proteasome R-HSA-5610780
Ub-specific processing proteases R-HSA-5689880
Degradation of AXIN R-HSA-4641257
Vpu mediated degradation of CD4 R-HSA-180534
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Interleukin-1 signaling R-HSA-9020702
Metabolism of RNA R-HSA-8953854
RAF/MAP kinase cascade R-HSA-5673001
Innate Immune System R-HSA-168249
MAPK6/MAPK4 signaling R-HSA-5687128
HIV Infection R-HSA-162906
RNA Polymerase II Transcription R-HSA-73857
Mitotic Anaphase R-HSA-68882
G1/S DNA Damage Checkpoints R-HSA-69615
Programmed Cell Death R-HSA-5357801
Infectious disease R-HSA-5663205
Cellular response to hypoxia R-HSA-1234174
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PCP/CE pathway R-HSA-4086400
Assembly of the pre-replicative complex R-HSA-68867
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Disease R-HSA-1643685
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 family signaling R-HSA-446652
Degradation of GLI2 by the proteasome R-HSA-5610783
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by ROBO receptors R-HSA-376176
Metabolism of amino acids and derivatives R-HSA-71291
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G2/M Checkpoints R-HSA-69481
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX3 R-HSA-8878159
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of polyamines R-HSA-351202
Ub-specific processing proteases R-HSA-5689880
Downstream TCR signaling R-HSA-202424
Post-translational protein modification R-HSA-597592
Signal Transduction R-HSA-162582
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX3 expression and activity R-HSA-8941858
PTEN Regulation R-HSA-6807070
Regulation of RAS by GAPs R-HSA-5658442
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Axon guidance R-HSA-422475
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCF dependent signaling in response to WNT R-HSA-201681
Intracellular signaling by second messengers R-HSA-9006925
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Vif-mediated degradation of APOBEC3G R-HSA-180585
G1/S Transition R-HSA-69206
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic G1 phase and G1/S transition R-HSA-453279
Orc1 removal from chromatin R-HSA-68949
Antigen processing-Cross presentation R-HSA-1236975
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog 'on' state R-HSA-5632684
Defective CFTR causes cystic fibrosis R-HSA-5678895
Host Interactions of HIV factors R-HSA-162909
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ABC transporter disorders R-HSA-5619084
Neutrophil degranulation R-HSA-6798695
G2/M Transition R-HSA-69275
Deubiquitination R-HSA-5688426
Degradation of DVL R-HSA-4641258
Cellular response to chemical stress R-HSA-9711123
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nervous system development R-HSA-9675108
Adaptive Immune System R-HSA-1280218
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by NOTCH R-HSA-157118
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
Transport of small molecules R-HSA-382551
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
KEAP1-NFE2L2 pathway R-HSA-9755511
Separation of Sister Chromatids R-HSA-2467813
Signaling by NOTCH4 R-HSA-9013694
Mitotic G2-G2/M phases R-HSA-453274
PIP3 activates AKT signaling R-HSA-1257604
M Phase R-HSA-68886
Developmental Biology R-HSA-1266738
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Vpu mediated degradation of CD4 R-HSA-180534
Disorders of transmembrane transporters R-HSA-5619115
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by WNT R-HSA-195721
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Apoptosis R-HSA-109581
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog ligand biogenesis R-HSA-5358346
MAPK family signaling cascades R-HSA-5683057
Metabolism of proteins R-HSA-392499
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of Apoptosis R-HSA-169911
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
S Phase R-HSA-69242
Cytokine Signaling in Immune system R-HSA-1280215
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Activation of NF-kappaB in B cells R-HSA-1169091
Switching of origins to a post-replicative state R-HSA-69052
Regulation of PTEN stability and activity R-HSA-8948751
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell Cycle Checkpoints R-HSA-69620
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle R-HSA-1640170
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
DNA Replication Pre-Initiation R-HSA-69002
TCR signaling R-HSA-202403
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
p53-Independent DNA Damage Response R-HSA-69610
Synthesis of DNA R-HSA-69239
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Class I MHC mediated antigen processing & presentation R-HSA-983169
Asymmetric localization of PCP proteins R-HSA-4608870
ER-Phagosome pathway R-HSA-1236974
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
ABC-family proteins mediated transport R-HSA-382556
Immune System R-HSA-168256
Signaling by Hedgehog R-HSA-5358351
DNA Replication R-HSA-69306
Signaling by Interleukins R-HSA-449147
CLEC7A (Dectin-1) signaling R-HSA-5607764
Asymmetric localization of PCP proteins R-HSA-4608870
HIV Infection R-HSA-162906
Signaling by NOTCH4 R-HSA-9013694
Neutrophil degranulation R-HSA-6798695
Programmed Cell Death R-HSA-5357801
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of DNA R-HSA-69239
Cellular responses to stimuli R-HSA-8953897
Neddylation R-HSA-8951664
Intracellular signaling by second messengers R-HSA-9006925
G2/M Checkpoints R-HSA-69481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Anaphase R-HSA-68882
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Vpu mediated degradation of CD4 R-HSA-180534
MAPK family signaling cascades R-HSA-5683057
Signaling by WNT R-HSA-195721
Mitotic Metaphase and Anaphase R-HSA-2555396
Transport of small molecules R-HSA-382551
Developmental Biology R-HSA-1266738
Regulation of RUNX2 expression and activity R-HSA-8939902
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX3 R-HSA-8878159
Signal Transduction R-HSA-162582
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog ligand biogenesis R-HSA-5358346
ABC-family proteins mediated transport R-HSA-382556
Negative regulation of NOTCH4 signaling R-HSA-9604323
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of beta-catenin by the destruction complex R-HSA-195253
Mitotic G2-G2/M phases R-HSA-453274
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK1/MAPK3 signaling R-HSA-5684996
Nervous system development R-HSA-9675108
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism R-HSA-1430728
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'off' state R-HSA-5610787
Downstream TCR signaling R-HSA-202424
Separation of Sister Chromatids R-HSA-2467813
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of DVL R-HSA-4641258
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G1 phase and G1/S transition R-HSA-453279
Antigen processing-Cross presentation R-HSA-1236975
Regulation of mitotic cell cycle R-HSA-453276
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Stabilization of p53 R-HSA-69541
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Regulation of Apoptosis R-HSA-169911
Regulation of PTEN stability and activity R-HSA-8948751
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Host Interactions of HIV factors R-HSA-162909
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of polyamines R-HSA-351202
Transcriptional regulation by RUNX1 R-HSA-8878171
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular response to hypoxia R-HSA-1234174
Cell Cycle Checkpoints R-HSA-69620
Immune System R-HSA-168256
PCP/CE pathway R-HSA-4086400
Signaling by NOTCH R-HSA-157118
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
CLEC7A (Dectin-1) signaling R-HSA-5607764
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Defective CFTR causes cystic fibrosis R-HSA-5678895
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of RAS by GAPs R-HSA-5658442
PIP3 activates AKT signaling R-HSA-1257604
G2/M Transition R-HSA-69275
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cyclin E associated events during G1/S transition R-HSA-69202
Ub-specific processing proteases R-HSA-5689880
Signaling by Hedgehog R-HSA-5358351
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Activation of NF-kappaB in B cells R-HSA-1169091
Axon guidance R-HSA-422475
DNA Replication R-HSA-69306
UCH proteinases R-HSA-5689603
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 signaling R-HSA-9020702
Metabolism of RNA R-HSA-8953854
Post-translational protein modification R-HSA-597592
TCR signaling R-HSA-202403
Adaptive Immune System R-HSA-1280218
S Phase R-HSA-69242
Assembly of the pre-replicative complex R-HSA-68867
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-1 family signaling R-HSA-446652
Cellular response to chemical stress R-HSA-9711123
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vif-mediated degradation of APOBEC3G R-HSA-180585
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of AXIN R-HSA-4641257
ER-Phagosome pathway R-HSA-1236974
Metabolism of proteins R-HSA-392499
Beta-catenin independent WNT signaling R-HSA-3858494
G1/S Transition R-HSA-69206
ABC transporter disorders R-HSA-5619084
Cellular responses to stress R-HSA-2262752
DNA Replication Pre-Initiation R-HSA-69002
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Innate Immune System R-HSA-168249
Disorders of transmembrane transporters R-HSA-5619115
Class I MHC mediated antigen processing & presentation R-HSA-983169
Apoptosis R-HSA-109581
Metabolism of amino acids and derivatives R-HSA-71291
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hedgehog 'on' state R-HSA-5632684
Switching of origins to a post-replicative state R-HSA-69052
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle, Mitotic R-HSA-69278
Metabolism of polyamines R-HSA-351202
Degradation of AXIN R-HSA-4641257
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX1 R-HSA-8878171
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing-Cross presentation R-HSA-1236975
Regulation of PTEN stability and activity R-HSA-8948751
ABC-family proteins mediated transport R-HSA-382556
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Mitotic Anaphase R-HSA-68882
Signaling by WNT R-HSA-195721
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of DVL R-HSA-4641258
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of RUNX3 expression and activity R-HSA-8941858
Nervous system development R-HSA-9675108
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'on' state R-HSA-5632684
DNA Replication R-HSA-69306
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation by RUNX3 R-HSA-8878159
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
Axon guidance R-HSA-422475
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
Regulation of RUNX2 expression and activity R-HSA-8939902
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ub-specific processing proteases R-HSA-5689880
Cellular response to chemical stress R-HSA-9711123
Mitotic G2-G2/M phases R-HSA-453274
Interleukin-1 signaling R-HSA-9020702
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Deubiquitination R-HSA-5688426
TCF dependent signaling in response to WNT R-HSA-201681
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of proteins R-HSA-392499
G2/M Checkpoints R-HSA-69481
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
TCR signaling R-HSA-202403
Transport of small molecules R-HSA-382551
Cellular response to hypoxia R-HSA-1234174
Regulation of RAS by GAPs R-HSA-5658442
Nuclear events mediated by NFE2L2 R-HSA-9759194
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent DNA Damage Response R-HSA-69610
Host Interactions of HIV factors R-HSA-162909
C-type lectin receptors (CLRs) R-HSA-5621481
Infectious disease R-HSA-5663205
Separation of Sister Chromatids R-HSA-2467813
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
G1/S Transition R-HSA-69206
Developmental Biology R-HSA-1266738
Apoptosis R-HSA-109581
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by NOTCH4 R-HSA-9013694
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK1/MAPK3 signaling R-HSA-5684996
HIV Infection R-HSA-162906
PTEN Regulation R-HSA-6807070
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Intracellular signaling by second messengers R-HSA-9006925
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Metaphase and Anaphase R-HSA-2555396
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Disorders of transmembrane transporters R-HSA-5619115
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of mitotic cell cycle R-HSA-453276
Defective CFTR causes cystic fibrosis R-HSA-5678895
RNA Polymerase II Transcription R-HSA-73857
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Dependent G1 DNA Damage Response R-HSA-69563
Synthesis of DNA R-HSA-69239
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
CLEC7A (Dectin-1) signaling R-HSA-5607764
ABC transporter disorders R-HSA-5619084
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Innate Immune System R-HSA-168249
Activation of NF-kappaB in B cells R-HSA-1169091
Beta-catenin independent WNT signaling R-HSA-3858494
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Post-translational protein modification R-HSA-597592
Metabolism R-HSA-1430728
FCERI mediated NF-kB activation R-HSA-2871837
Stabilization of p53 R-HSA-69541
Disease R-HSA-1643685
Neddylation R-HSA-8951664
Neutrophil degranulation R-HSA-6798695
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of expression of SLITs and ROBOs R-HSA-9010553
RAF/MAP kinase cascade R-HSA-5673001
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signal Transduction R-HSA-162582
Hh mutants are degraded by ERAD R-HSA-5362768
ER-Phagosome pathway R-HSA-1236974
Signaling by NOTCH R-HSA-157118
PCP/CE pathway R-HSA-4086400
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G2/M Transition R-HSA-69275
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Programmed Cell Death R-HSA-5357801
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Hedgehog R-HSA-5358351
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream TCR signaling R-HSA-202424
Interleukin-1 family signaling R-HSA-446652
Hedgehog 'off' state R-HSA-5610787
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Interleukins R-HSA-449147
M Phase R-HSA-68886
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle R-HSA-1640170
Regulation of Apoptosis R-HSA-169911
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
RNA Polymerase II Transcription R-HSA-73857
Cyclin E associated events during G1/S transition R-HSA-69202
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256
CLEC7A (Dectin-1) signaling R-HSA-5607764
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing-Cross presentation R-HSA-1236975
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of RNA R-HSA-8953854
MAPK family signaling cascades R-HSA-5683057
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of beta-catenin by the destruction complex R-HSA-195253
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle, Mitotic R-HSA-69278
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RUNX2 expression and activity R-HSA-8939902
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX3 R-HSA-8878159
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Anaphase R-HSA-68882
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vpu mediated degradation of CD4 R-HSA-180534
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RAS by GAPs R-HSA-5658442
Interleukin-1 family signaling R-HSA-446652
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G1 phase and G1/S transition R-HSA-453279
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
DNA Replication Pre-Initiation R-HSA-69002
ER-Phagosome pathway R-HSA-1236974
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Adaptive Immune System R-HSA-1280218
Degradation of GLI1 by the proteasome R-HSA-5610780
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of polyamines R-HSA-351202
Cellular response to chemical stress R-HSA-9711123
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of amino acids and derivatives R-HSA-71291
M Phase R-HSA-68886
Cellular responses to stimuli R-HSA-8953897
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 signaling R-HSA-9020702
FCERI mediated NF-kB activation R-HSA-2871837
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by Interleukins R-HSA-449147
Intracellular signaling by second messengers R-HSA-9006925
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RUNX3 expression and activity R-HSA-8941858
Innate Immune System R-HSA-168249
Host Interactions of HIV factors R-HSA-162909
ABC transporter disorders R-HSA-5619084
Disease R-HSA-1643685
Assembly of the pre-replicative complex R-HSA-68867
HIV Infection R-HSA-162906
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Checkpoints R-HSA-69481
Switching of origins to a post-replicative state R-HSA-69052
Vif-mediated degradation of APOBEC3G R-HSA-180585
Post-translational protein modification R-HSA-597592
Developmental Biology R-HSA-1266738
Degradation of AXIN R-HSA-4641257
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hedgehog 'off' state R-HSA-5610787
TCR signaling R-HSA-202403
Metabolism R-HSA-1430728
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by WNT R-HSA-195721
Disorders of transmembrane transporters R-HSA-5619115
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Nervous system development R-HSA-9675108
Degradation of DVL R-HSA-4641258
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH4 R-HSA-9013694
Neutrophil degranulation R-HSA-6798695
Infectious disease R-HSA-5663205
Hedgehog 'on' state R-HSA-5632684
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of Apoptosis R-HSA-169911
Cell Cycle R-HSA-1640170
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transport of small molecules R-HSA-382551
PTEN Regulation R-HSA-6807070
Activation of NF-kappaB in B cells R-HSA-1169091
G1/S Transition R-HSA-69206
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular response to hypoxia R-HSA-1234174
S Phase R-HSA-69242
DNA Replication R-HSA-69306
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
UCH proteinases R-HSA-5689603
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream TCR signaling R-HSA-202424
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PCP/CE pathway R-HSA-4086400
C-type lectin receptors (CLRs) R-HSA-5621481
Asymmetric localization of PCP proteins R-HSA-4608870
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of GLI2 by the proteasome R-HSA-5610783
Neddylation R-HSA-8951664
Deubiquitination R-HSA-5688426
ABC-family proteins mediated transport R-HSA-382556
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Apoptosis R-HSA-109581
Cellular responses to stress R-HSA-2262752
Stabilization of p53 R-HSA-69541
Ub-specific processing proteases R-HSA-5689880
G2/M Transition R-HSA-69275
Synthesis of DNA R-HSA-69239
Beta-catenin independent WNT signaling R-HSA-3858494
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle Checkpoints R-HSA-69620
Regulation of PTEN stability and activity R-HSA-8948751
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of proteins R-HSA-392499
Axon guidance R-HSA-422475
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Programmed Cell Death R-HSA-5357801
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by ROBO receptors R-HSA-376176
Signal Transduction R-HSA-162582
RAF/MAP kinase cascade R-HSA-5673001
Separation of Sister Chromatids R-HSA-2467813
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by Hedgehog R-HSA-5358351
Cytokine Signaling in Immune system R-HSA-1280215
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
TCF dependent signaling in response to WNT R-HSA-201681
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Neutrophil degranulation R-HSA-6798695
NIK-->noncanonical NF-kB signaling R-HSA-5676590
RNA Polymerase II Transcription R-HSA-73857
Signaling by WNT R-HSA-195721
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
C-type lectin receptors (CLRs) R-HSA-5621481
PTEN Regulation R-HSA-6807070
Switching of origins to a post-replicative state R-HSA-69052
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Disease R-HSA-1643685
Post-translational protein modification R-HSA-597592
Vif-mediated degradation of APOBEC3G R-HSA-180585
Activation of NF-kappaB in B cells R-HSA-1169091
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
Degradation of beta-catenin by the destruction complex R-HSA-195253
Separation of Sister Chromatids R-HSA-2467813
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication Pre-Initiation R-HSA-69002
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
Metabolism of RNA R-HSA-8953854
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of proteins R-HSA-392499
Signaling by NOTCH4 R-HSA-9013694
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle, Mitotic R-HSA-69278
PCP/CE pathway R-HSA-4086400
Disorders of transmembrane transporters R-HSA-5619115
Generic Transcription Pathway R-HSA-212436
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ABC-family proteins mediated transport R-HSA-382556
Cellular response to hypoxia R-HSA-1234174
Regulation of RAS by GAPs R-HSA-5658442
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
Stabilization of p53 R-HSA-69541
PIP3 activates AKT signaling R-HSA-1257604
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of polyamines R-HSA-351202
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stress R-HSA-2262752
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Assembly of the pre-replicative complex R-HSA-68867
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle R-HSA-1640170
TCF dependent signaling in response to WNT R-HSA-201681
Transport of small molecules R-HSA-382551
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of DVL R-HSA-4641258
Hedgehog 'on' state R-HSA-5632684
Neddylation R-HSA-8951664
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic Metaphase and Anaphase R-HSA-2555396
Intracellular signaling by second messengers R-HSA-9006925
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hh mutants abrogate ligand secretion R-HSA-5387390
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of Apoptosis R-HSA-169911
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of amino acids and derivatives R-HSA-71291
Synthesis of DNA R-HSA-69239
Ub-specific processing proteases R-HSA-5689880
Orc1 removal from chromatin R-HSA-68949
Innate Immune System R-HSA-168249
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
ABC transporter disorders R-HSA-5619084
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
G2/M Checkpoints R-HSA-69481
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stimuli R-HSA-8953897
Beta-catenin independent WNT signaling R-HSA-3858494
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular response to chemical stress R-HSA-9711123
Infectious disease R-HSA-5663205
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism R-HSA-1430728
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
UCH proteinases R-HSA-5689603
Hedgehog 'off' state R-HSA-5610787
Hedgehog ligand biogenesis R-HSA-5358346
p53-Dependent G1 DNA Damage Response R-HSA-69563
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Asymmetric localization of PCP proteins R-HSA-4608870
CLEC7A (Dectin-1) signaling R-HSA-5607764
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S Transition R-HSA-69206
DNA Replication R-HSA-69306
MAPK family signaling cascades R-HSA-5683057
Mitotic G2-G2/M phases R-HSA-453274
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Apoptosis R-HSA-109581
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vpu mediated degradation of CD4 R-HSA-180534
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of GLI2 by the proteasome R-HSA-5610783
ER-Phagosome pathway R-HSA-1236974
Deubiquitination R-HSA-5688426
Regulation of RUNX2 expression and activity R-HSA-8939902
Downstream TCR signaling R-HSA-202424
Regulation of expression of SLITs and ROBOs R-HSA-9010553
HIV Infection R-HSA-162906
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCR signaling R-HSA-202403
Antigen processing-Cross presentation R-HSA-1236975
Interleukin-1 signaling R-HSA-9020702
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Class I MHC mediated antigen processing & presentation R-HSA-983169
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
Signaling by ROBO receptors R-HSA-376176
p53-Independent DNA Damage Response R-HSA-69610
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX1 R-HSA-8878171
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin E associated events during G1/S transition R-HSA-69202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-1 family signaling R-HSA-446652
Degradation of AXIN R-HSA-4641257
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic Anaphase R-HSA-68882
FCERI mediated NF-kB activation R-HSA-2871837
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signal Transduction R-HSA-162582
Regulation of RUNX3 expression and activity R-HSA-8941858
S Phase R-HSA-69242
M Phase R-HSA-68886
Orc1 removal from chromatin R-HSA-68949
Programmed Cell Death R-HSA-5357801
Mitotic Metaphase and Anaphase R-HSA-2555396
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stimuli R-HSA-8953897
Downstream TCR signaling R-HSA-202424
Cellular response to chemical stress R-HSA-9711123
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by Hedgehog R-HSA-5358351
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Intracellular signaling by second messengers R-HSA-9006925
Generic Transcription Pathway R-HSA-212436
Neutrophil degranulation R-HSA-6798695
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Class I MHC mediated antigen processing & presentation R-HSA-983169
DNA Replication R-HSA-69306
KEAP1-NFE2L2 pathway R-HSA-9755511
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hedgehog 'on' state R-HSA-5632684
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Antigen processing-Cross presentation R-HSA-1236975
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cell Cycle, Mitotic R-HSA-69278
Signaling by NOTCH4 R-HSA-9013694
HIV Infection R-HSA-162906
Metabolism of proteins R-HSA-392499
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
Signaling by WNT R-HSA-195721
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX3 expression and activity R-HSA-8941858
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stress R-HSA-2262752
MAPK6/MAPK4 signaling R-HSA-5687128
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Metabolism of polyamines R-HSA-351202
FCERI mediated NF-kB activation R-HSA-2871837
Developmental Biology R-HSA-1266738
Immune System R-HSA-168256
Beta-catenin independent WNT signaling R-HSA-3858494
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'off' state R-HSA-5610787
Cell Cycle Checkpoints R-HSA-69620
G1/S DNA Damage Checkpoints R-HSA-69615
M Phase R-HSA-68886
Regulation of RAS by GAPs R-HSA-5658442
TCR signaling R-HSA-202403
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX2 expression and activity R-HSA-8939902
Deubiquitination R-HSA-5688426
G2/M Transition R-HSA-69275
Hh mutants abrogate ligand secretion R-HSA-5387390
G1/S Transition R-HSA-69206
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Infectious disease R-HSA-5663205
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Separation of Sister Chromatids R-HSA-2467813
Vpu mediated degradation of CD4 R-HSA-180534
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 family signaling R-HSA-446652
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mitotic cell cycle R-HSA-453276
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PIP3 activates AKT signaling R-HSA-1257604
PTEN Regulation R-HSA-6807070
DNA Replication Pre-Initiation R-HSA-69002
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of Apoptosis R-HSA-169911
Degradation of DVL R-HSA-4641258
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Post-translational protein modification R-HSA-597592
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of RNA R-HSA-8953854
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Dependent G1 DNA Damage Response R-HSA-69563
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
ABC-family proteins mediated transport R-HSA-382556
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by ROBO receptors R-HSA-376176
Nuclear events mediated by NFE2L2 R-HSA-9759194
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of AXIN R-HSA-4641257
Stabilization of p53 R-HSA-69541
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
G2/M Checkpoints R-HSA-69481
Axon guidance R-HSA-422475
ER-Phagosome pathway R-HSA-1236974
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants are degraded by ERAD R-HSA-5362768
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent DNA Damage Response R-HSA-69610
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by NOTCH R-HSA-157118
Interleukin-1 signaling R-HSA-9020702
ABC transporter disorders R-HSA-5619084
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Defective CFTR causes cystic fibrosis R-HSA-5678895
Neddylation R-HSA-8951664
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
MAPK family signaling cascades R-HSA-5683057
S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Assembly of the pre-replicative complex R-HSA-68867
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX1 R-HSA-8878171
Ub-specific processing proteases R-HSA-5689880
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transport of small molecules R-HSA-382551
Synthesis of DNA R-HSA-69239
Metabolism of amino acids and derivatives R-HSA-71291
Cyclin E associated events during G1/S transition R-HSA-69202
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic Anaphase R-HSA-68882
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by Interleukins R-HSA-449147
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of polyamines R-HSA-351202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI2 by the proteasome R-HSA-5610783
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic Anaphase R-HSA-68882
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cyclin E associated events during G1/S transition R-HSA-69202
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
Intracellular signaling by second messengers R-HSA-9006925
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Innate Immune System R-HSA-168249
Hedgehog 'off' state R-HSA-5610787
CLEC7A (Dectin-1) signaling R-HSA-5607764
Adaptive Immune System R-HSA-1280218
KEAP1-NFE2L2 pathway R-HSA-9755511
Post-translational protein modification R-HSA-597592
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK family signaling cascades R-HSA-5683057
Cell Cycle R-HSA-1640170
Regulation of RAS by GAPs R-HSA-5658442
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH4 R-HSA-9013694
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'on' state R-HSA-5632684
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Hedgehog R-HSA-5358351
HIV Infection R-HSA-162906
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-1 signaling R-HSA-9020702
Cell Cycle Checkpoints R-HSA-69620
Neutrophil degranulation R-HSA-6798695
PTEN Regulation R-HSA-6807070
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G2/M Transition R-HSA-69275
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S Transition R-HSA-69206
DNA Replication Pre-Initiation R-HSA-69002
Neddylation R-HSA-8951664
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
Downstream TCR signaling R-HSA-202424
Nuclear events mediated by NFE2L2 R-HSA-9759194
Immune System R-HSA-168256
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX1 R-HSA-8878171
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic G2-G2/M phases R-HSA-453274
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
ER-Phagosome pathway R-HSA-1236974
M Phase R-HSA-68886
Host Interactions of HIV factors R-HSA-162909
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
Disease R-HSA-1643685
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Orc1 removal from chromatin R-HSA-68949
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of proteins R-HSA-392499
Degradation of AXIN R-HSA-4641257
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
UCH proteinases R-HSA-5689603
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX2 R-HSA-8878166
Deubiquitination R-HSA-5688426
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cytokine Signaling in Immune system R-HSA-1280215
DNA Replication R-HSA-69306
Asymmetric localization of PCP proteins R-HSA-4608870
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH R-HSA-157118
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Assembly of the pre-replicative complex R-HSA-68867
Vpu mediated degradation of CD4 R-HSA-180534
RNA Polymerase II Transcription R-HSA-73857
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Stabilization of p53 R-HSA-69541
Cellular response to chemical stress R-HSA-9711123
G1/S DNA Damage Checkpoints R-HSA-69615
Defective CFTR causes cystic fibrosis R-HSA-5678895
TCR signaling R-HSA-202403
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Developmental Biology R-HSA-1266738
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
C-type lectin receptors (CLRs) R-HSA-5621481
Hh mutants abrogate ligand secretion R-HSA-5387390
Transport of small molecules R-HSA-382551
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Synthesis of DNA R-HSA-69239
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent DNA Damage Response R-HSA-69610
Mitotic G1 phase and G1/S transition R-HSA-453279
Disorders of transmembrane transporters R-HSA-5619115
Activation of NF-kappaB in B cells R-HSA-1169091
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stress R-HSA-2262752
Signal Transduction R-HSA-162582
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by Interleukins R-HSA-449147
ABC-family proteins mediated transport R-HSA-382556
Axon guidance R-HSA-422475
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
Nervous system development R-HSA-9675108
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by ROBO receptors R-HSA-376176
Regulation of RUNX2 expression and activity R-HSA-8939902
PCP/CE pathway R-HSA-4086400
Cellular responses to stimuli R-HSA-8953897
Mitotic Metaphase and Anaphase R-HSA-2555396
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX3 R-HSA-8878159
Apoptosis R-HSA-109581
Regulation of Apoptosis R-HSA-169911
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transcriptional regulation by RUNX1 R-HSA-8878171
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
Cellular responses to stimuli R-HSA-8953897
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of polyamines R-HSA-351202
Developmental Biology R-HSA-1266738
ABC transporter disorders R-HSA-5619084
Host Interactions of HIV factors R-HSA-162909
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of amino acids and derivatives R-HSA-71291
Infectious disease R-HSA-5663205
S Phase R-HSA-69242
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK6/MAPK4 signaling R-HSA-5687128
Class I MHC mediated antigen processing & presentation R-HSA-983169
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by ROBO receptors R-HSA-376176
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nervous system development R-HSA-9675108
Regulation of PTEN stability and activity R-HSA-8948751
Deubiquitination R-HSA-5688426
Cyclin E associated events during G1/S transition R-HSA-69202
DNA Replication Pre-Initiation R-HSA-69002
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
Disease R-HSA-1643685
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic G1 phase and G1/S transition R-HSA-453279
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by Interleukins R-HSA-449147
PIP3 activates AKT signaling R-HSA-1257604
Separation of Sister Chromatids R-HSA-2467813
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX2 R-HSA-8878166
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of GLI2 by the proteasome R-HSA-5610783
ABC-family proteins mediated transport R-HSA-382556
M Phase R-HSA-68886
Hh mutants are degraded by ERAD R-HSA-5362768
Cytokine Signaling in Immune system R-HSA-1280215
HIV Infection R-HSA-162906
Disorders of transmembrane transporters R-HSA-5619115
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH4 R-HSA-9013694
Orc1 removal from chromatin R-HSA-68949
Assembly of the pre-replicative complex R-HSA-68867
Regulation of RAS by GAPs R-HSA-5658442
Metabolism R-HSA-1430728
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular response to hypoxia R-HSA-1234174
Negative regulation of NOTCH4 signaling R-HSA-9604323
Generic Transcription Pathway R-HSA-212436
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of Apoptosis R-HSA-169911
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
Hedgehog 'off' state R-HSA-5610787
Regulation of RUNX3 expression and activity R-HSA-8941858
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of DVL R-HSA-4641258
ER-Phagosome pathway R-HSA-1236974
Degradation of GLI1 by the proteasome R-HSA-5610780
Synthesis of DNA R-HSA-69239
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Switching of origins to a post-replicative state R-HSA-69052
Neutrophil degranulation R-HSA-6798695
Downstream TCR signaling R-HSA-202424
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
Neddylation R-HSA-8951664
Cell Cycle R-HSA-1640170
Axon guidance R-HSA-422475
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Post-translational protein modification R-HSA-597592
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of AXIN R-HSA-4641257
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
Gene expression (Transcription) R-HSA-74160
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Innate Immune System R-HSA-168249
Interleukin-1 family signaling R-HSA-446652
Cell Cycle, Mitotic R-HSA-69278
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular responses to stress R-HSA-2262752
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ub-specific processing proteases R-HSA-5689880
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of RNA R-HSA-8953854
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle Checkpoints R-HSA-69620
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Anaphase R-HSA-68882
Nuclear events mediated by NFE2L2 R-HSA-9759194
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Apoptosis R-HSA-109581
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent DNA Damage Response R-HSA-69610
Asymmetric localization of PCP proteins R-HSA-4608870
DNA Replication R-HSA-69306
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signal Transduction R-HSA-162582
Regulation of expression of SLITs and ROBOs R-HSA-9010553
UCH proteinases R-HSA-5689603
TCF dependent signaling in response to WNT R-HSA-201681
Transport of small molecules R-HSA-382551
Stabilization of p53 R-HSA-69541
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684

Expression Atlas ENSG00000163636
NCBI gene (formerly Entrezgene) 9861
GeneCards 9564
HGNC Symbol HGNC:9564
MIM gene 617857
UniProtKB Gene Name Q15008
WikiGene 9861
Gene: PSMB7
Ensembl ID : ENSG00000136930
Description: proteasome 20S subunit beta 7
Gene Synonyms: Z
6 APIs:
218 Possible Orthologues:

Degradation of GLI2 by the proteasome R-HSA-5610783
Disease R-HSA-1643685
Metabolism of RNA R-HSA-8953854
FCERI mediated NF-kB activation R-HSA-2871837
Neddylation R-HSA-8951664
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1 DNA Damage Response R-HSA-69563
Nervous system development R-HSA-9675108
Programmed Cell Death R-HSA-5357801
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of expression of SLITs and ROBOs R-HSA-9010553
FCERI mediated NF-kB activation R-HSA-2871837
C-type lectin receptors (CLRs) R-HSA-5621481
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of RNA R-HSA-8953854
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interleukin-1 signaling R-HSA-9020702
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to chemical stress R-HSA-9711123
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by WNT R-HSA-195721
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Negative regulation of NOTCH4 signaling R-HSA-9604323
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Ub-specific processing proteases R-HSA-5689880
HIV Infection R-HSA-162906
Orc1 removal from chromatin R-HSA-68949
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
PTEN Regulation R-HSA-6807070
Regulation of RAS by GAPs R-HSA-5658442
Gene expression (Transcription) R-HSA-74160
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Transport of small molecules R-HSA-382551
Switching of origins to a post-replicative state R-HSA-69052
Regulation of mitotic cell cycle R-HSA-453276
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RNA Polymerase II Transcription R-HSA-73857
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Synthesis of DNA R-HSA-69239
Apoptosis R-HSA-109581
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Asymmetric localization of PCP proteins R-HSA-4608870
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of RUNX2 expression and activity R-HSA-8939902
Intracellular signaling by second messengers R-HSA-9006925
Infectious disease R-HSA-5663205
Post-translational protein modification R-HSA-597592
ABC-family proteins mediated transport R-HSA-382556
Axon guidance R-HSA-422475
Regulation of Apoptosis R-HSA-169911
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of PTEN stability and activity R-HSA-8948751
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
Degradation of DVL R-HSA-4641258
Hedgehog 'on' state R-HSA-5632684
PCP/CE pathway R-HSA-4086400
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Independent DNA Damage Response R-HSA-69610
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
ER-Phagosome pathway R-HSA-1236974
Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
Hedgehog ligand biogenesis R-HSA-5358346
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH4 R-HSA-9013694
Adaptive Immune System R-HSA-1280218
Assembly of the pre-replicative complex R-HSA-68867
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by NOTCH R-HSA-157118
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX3 R-HSA-8878159
Disorders of transmembrane transporters R-HSA-5619115
Mitotic Metaphase and Anaphase R-HSA-2555396
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Disease R-HSA-1643685
Signaling by ROBO receptors R-HSA-376176
Mitotic Anaphase R-HSA-68882
ABC transporter disorders R-HSA-5619084
Degradation of AXIN R-HSA-4641257
Defective CFTR causes cystic fibrosis R-HSA-5678895
Separation of Sister Chromatids R-HSA-2467813
DNA Replication R-HSA-69306
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 family signaling R-HSA-446652
Stabilization of p53 R-HSA-69541
Hedgehog 'off' state R-HSA-5610787
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Deubiquitination R-HSA-5688426
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
UCH proteinases R-HSA-5689603
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by Interleukins R-HSA-449147
Signaling by NOTCH4 R-HSA-9013694
Orc1 removal from chromatin R-HSA-68949
Degradation of DVL R-HSA-4641258
Cellular response to hypoxia R-HSA-1234174
Axon guidance R-HSA-422475
Ub-specific processing proteases R-HSA-5689880
Switching of origins to a post-replicative state R-HSA-69052
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of polyamines R-HSA-351202
Downstream TCR signaling R-HSA-202424
Metabolism of RNA R-HSA-8953854
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neutrophil degranulation R-HSA-6798695
Synthesis of DNA R-HSA-69239
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of amino acids and derivatives R-HSA-71291
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Assembly of the pre-replicative complex R-HSA-68867
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic G2-G2/M phases R-HSA-453274
Generic Transcription Pathway R-HSA-212436
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Stabilization of p53 R-HSA-69541
Degradation of GLI2 by the proteasome R-HSA-5610783
RAF/MAP kinase cascade R-HSA-5673001
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652
PTEN Regulation R-HSA-6807070
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX1 R-HSA-8878171
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog 'off' state R-HSA-5610787
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX3 R-HSA-8878159
ABC transporter disorders R-HSA-5619084
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 signaling R-HSA-9020702
Transport of small molecules R-HSA-382551
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Metaphase and Anaphase R-HSA-2555396
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stimuli R-HSA-8953897
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
Separation of Sister Chromatids R-HSA-2467813
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of AXIN R-HSA-4641257
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S Transition R-HSA-69206
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Apoptosis R-HSA-109581
Neddylation R-HSA-8951664
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism R-HSA-1430728
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mitotic cell cycle R-HSA-453276
Mitotic Anaphase R-HSA-68882
Cell Cycle Checkpoints R-HSA-69620
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of beta-catenin by the destruction complex R-HSA-195253
DNA Replication Pre-Initiation R-HSA-69002
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular response to chemical stress R-HSA-9711123
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by ROBO receptors R-HSA-376176
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
HIV Infection R-HSA-162906
TCR signaling R-HSA-202403
Signaling by NOTCH R-HSA-157118
ER-Phagosome pathway R-HSA-1236974
S Phase R-HSA-69242
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
UCH proteinases R-HSA-5689603
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Interleukins R-HSA-449147
Regulation of RUNX3 expression and activity R-HSA-8941858
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Checkpoints R-HSA-69481
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Programmed Cell Death R-HSA-5357801
Cytokine Signaling in Immune system R-HSA-1280215
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Hedgehog R-HSA-5358351
MAPK family signaling cascades R-HSA-5683057
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants abrogate ligand secretion R-HSA-5387390
PIP3 activates AKT signaling R-HSA-1257604
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by WNT R-HSA-195721
Hedgehog 'on' state R-HSA-5632684
MAPK1/MAPK3 signaling R-HSA-5684996
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of PTEN stability and activity R-HSA-8948751
Immune System R-HSA-168256
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vif-mediated degradation of APOBEC3G R-HSA-180585
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Host Interactions of HIV factors R-HSA-162909
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK6/MAPK4 signaling R-HSA-5687128
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Innate Immune System R-HSA-168249
p53-Independent DNA Damage Response R-HSA-69610
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog 'off' state R-HSA-5610787
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of polyamines R-HSA-351202
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog ligand biogenesis R-HSA-5358346
Infectious disease R-HSA-5663205
DNA Replication R-HSA-69306
Disorders of transmembrane transporters R-HSA-5619115
G2/M Checkpoints R-HSA-69481
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Innate Immune System R-HSA-168249
M Phase R-HSA-68886
Stabilization of p53 R-HSA-69541
G2/M Transition R-HSA-69275
Antigen processing-Cross presentation R-HSA-1236975
Disease R-HSA-1643685
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH4 R-HSA-9013694
RNA Polymerase II Transcription R-HSA-73857
Downstream TCR signaling R-HSA-202424
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of Apoptosis R-HSA-169911
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCR signaling R-HSA-202403
Signal Transduction R-HSA-162582
G1/S Transition R-HSA-69206
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cyclin E associated events during G1/S transition R-HSA-69202
Assembly of the pre-replicative complex R-HSA-68867
Class I MHC mediated antigen processing & presentation R-HSA-983169
Adaptive Immune System R-HSA-1280218
Interleukin-1 family signaling R-HSA-446652
Metabolism of amino acids and derivatives R-HSA-71291
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cellular response to chemical stress R-HSA-9711123
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stress R-HSA-2262752
Signaling by Interleukins R-HSA-449147
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by ROBO receptors R-HSA-376176
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1 DNA Damage Response R-HSA-69563
Host Interactions of HIV factors R-HSA-162909
Cellular response to hypoxia R-HSA-1234174
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Post-translational protein modification R-HSA-597592
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Anaphase R-HSA-68882
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Synthesis of DNA R-HSA-69239
Transport of small molecules R-HSA-382551
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Metaphase and Anaphase R-HSA-2555396
C-type lectin receptors (CLRs) R-HSA-5621481
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PCP/CE pathway R-HSA-4086400
HIV Infection R-HSA-162906
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX3 expression and activity R-HSA-8941858
Nervous system development R-HSA-9675108
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
Axon guidance R-HSA-422475
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
Beta-catenin independent WNT signaling R-HSA-3858494
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC transporter disorders R-HSA-5619084
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of proteins R-HSA-392499
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RAF/MAP kinase cascade R-HSA-5673001
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Orc1 removal from chromatin R-HSA-68949
PTEN Regulation R-HSA-6807070
KEAP1-NFE2L2 pathway R-HSA-9755511
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Apoptosis R-HSA-109581
Signaling by NOTCH R-HSA-157118
Deubiquitination R-HSA-5688426
FCERI mediated NF-kB activation R-HSA-2871837
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of PTEN stability and activity R-HSA-8948751
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle Checkpoints R-HSA-69620
ER-Phagosome pathway R-HSA-1236974
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle R-HSA-1640170
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Immune System R-HSA-168256
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX1 R-HSA-8878171
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 signaling R-HSA-9020702
MAPK family signaling cascades R-HSA-5683057
Vif-mediated degradation of APOBEC3G R-HSA-180585
Neutrophil degranulation R-HSA-6798695
ABC-family proteins mediated transport R-HSA-382556
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S DNA Damage Checkpoints R-HSA-69615
PIP3 activates AKT signaling R-HSA-1257604
Separation of Sister Chromatids R-HSA-2467813
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
Switching of origins to a post-replicative state R-HSA-69052
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI2 by the proteasome R-HSA-5610783
Interleukin-1 family signaling R-HSA-446652
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Regulation of Apoptosis R-HSA-169911
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RUNX2 expression and activity R-HSA-8939902
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Apoptosis R-HSA-109581
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RAF/MAP kinase cascade R-HSA-5673001
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PTEN Regulation R-HSA-6807070
Signal Transduction R-HSA-162582
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC-family proteins mediated transport R-HSA-382556
RNA Polymerase II Transcription R-HSA-73857
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
G2/M Transition R-HSA-69275
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'off' state R-HSA-5610787
Deubiquitination R-HSA-5688426
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
TCF dependent signaling in response to WNT R-HSA-201681
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional regulation by RUNX1 R-HSA-8878171
G1/S DNA Damage Checkpoints R-HSA-69615
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G2-G2/M phases R-HSA-453274
MAPK family signaling cascades R-HSA-5683057
TCR signaling R-HSA-202403
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
Mitotic G1 phase and G1/S transition R-HSA-453279
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Vpu mediated degradation of CD4 R-HSA-180534
Separation of Sister Chromatids R-HSA-2467813
Metabolism R-HSA-1430728
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
CLEC7A (Dectin-1) signaling R-HSA-5607764
Axon guidance R-HSA-422475
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX3 expression and activity R-HSA-8941858
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
HIV Infection R-HSA-162906
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hh mutants are degraded by ERAD R-HSA-5362768
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
Regulation of RAS by GAPs R-HSA-5658442
G2/M Checkpoints R-HSA-69481
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
Signaling by NOTCH4 R-HSA-9013694
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cyclin E associated events during G1/S transition R-HSA-69202
UCH proteinases R-HSA-5689603
Neutrophil degranulation R-HSA-6798695
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
PCP/CE pathway R-HSA-4086400
Immune System R-HSA-168256
G1/S Transition R-HSA-69206
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle, Mitotic R-HSA-69278
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
Synthesis of DNA R-HSA-69239
Metabolism of RNA R-HSA-8953854
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transport of small molecules R-HSA-382551
Orc1 removal from chromatin R-HSA-68949
Signaling by Hedgehog R-HSA-5358351
Interleukin-1 signaling R-HSA-9020702
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of DVL R-HSA-4641258
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Cell Cycle Checkpoints R-HSA-69620
C-type lectin receptors (CLRs) R-HSA-5621481
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle R-HSA-1640170
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream TCR signaling R-HSA-202424
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Gene expression (Transcription) R-HSA-74160
Ub-specific processing proteases R-HSA-5689880
Disorders of transmembrane transporters R-HSA-5619115
Host Interactions of HIV factors R-HSA-162909
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Programmed Cell Death R-HSA-5357801
Metabolism of polyamines R-HSA-351202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
Neddylation R-HSA-8951664
DNA Replication R-HSA-69306
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ER-Phagosome pathway R-HSA-1236974
Antigen processing-Cross presentation R-HSA-1236975
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by ROBO receptors R-HSA-376176
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of DVL R-HSA-4641258
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
Cyclin E associated events during G1/S transition R-HSA-69202
ABC transporter disorders R-HSA-5619084
Signaling by Interleukins R-HSA-449147
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH4 R-HSA-9013694
Hh mutants abrogate ligand secretion R-HSA-5387390
PTEN Regulation R-HSA-6807070
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G2-G2/M phases R-HSA-453274
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Synthesis of DNA R-HSA-69239
Deubiquitination R-HSA-5688426
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TCR signaling R-HSA-202403
Regulation of RUNX2 expression and activity R-HSA-8939902
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Generic Transcription Pathway R-HSA-212436
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Beta-catenin independent WNT signaling R-HSA-3858494
Ub-specific processing proteases R-HSA-5689880
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Switching of origins to a post-replicative state R-HSA-69052
Orc1 removal from chromatin R-HSA-68949
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Programmed Cell Death R-HSA-5357801
M Phase R-HSA-68886
NIK-->noncanonical NF-kB signaling R-HSA-5676590
C-type lectin receptors (CLRs) R-HSA-5621481
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Separation of Sister Chromatids R-HSA-2467813
Assembly of the pre-replicative complex R-HSA-68867
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S DNA Damage Checkpoints R-HSA-69615
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Independent DNA Damage Response R-HSA-69610
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH R-HSA-157118
Hh mutants are degraded by ERAD R-HSA-5362768
Nervous system development R-HSA-9675108
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'off' state R-HSA-5610787
Host Interactions of HIV factors R-HSA-162909
Neutrophil degranulation R-HSA-6798695
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
RAF/MAP kinase cascade R-HSA-5673001
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
Signal Transduction R-HSA-162582
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of PTEN stability and activity R-HSA-8948751
Intracellular signaling by second messengers R-HSA-9006925
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Adaptive Immune System R-HSA-1280218
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic Metaphase and Anaphase R-HSA-2555396
HIV Infection R-HSA-162906
Downstream TCR signaling R-HSA-202424
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle, Mitotic R-HSA-69278
ABC-family proteins mediated transport R-HSA-382556
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of Apoptosis R-HSA-169911
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Axon guidance R-HSA-422475
PCP/CE pathway R-HSA-4086400
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
Developmental Biology R-HSA-1266738
Transport of small molecules R-HSA-382551
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle R-HSA-1640170
Immune System R-HSA-168256
Transcriptional regulation by RUNX2 R-HSA-8878166
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog ligand biogenesis R-HSA-5358346
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK family signaling cascades R-HSA-5683057
Cell Cycle Checkpoints R-HSA-69620
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Replication Pre-Initiation R-HSA-69002
Degradation of beta-catenin by the destruction complex R-HSA-195253
Innate Immune System R-HSA-168249
Apoptosis R-HSA-109581
Interleukin-1 family signaling R-HSA-446652
DNA Replication R-HSA-69306
Cellular response to hypoxia R-HSA-1234174
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of AXIN R-HSA-4641257
Regulation of RUNX3 expression and activity R-HSA-8941858
Post-translational protein modification R-HSA-597592
Cytokine Signaling in Immune system R-HSA-1280215
UCH proteinases R-HSA-5689603
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signaling by WNT R-HSA-195721
Neddylation R-HSA-8951664
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
Metabolism of amino acids and derivatives R-HSA-71291
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism R-HSA-1430728
Interleukin-1 signaling R-HSA-9020702
G2/M Transition R-HSA-69275
G1/S Transition R-HSA-69206
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of polyamines R-HSA-351202
Mitotic Anaphase R-HSA-68882
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Innate Immune System R-HSA-168249
Negative regulation of NOTCH4 signaling R-HSA-9604323
Gene expression (Transcription) R-HSA-74160
Degradation of GLI2 by the proteasome R-HSA-5610783
PTEN Regulation R-HSA-6807070
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by Hedgehog R-HSA-5358351
Interleukin-1 signaling R-HSA-9020702
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signal Transduction R-HSA-162582
MAPK6/MAPK4 signaling R-HSA-5687128
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
S Phase R-HSA-69242
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX1 R-HSA-8878171
G2/M Transition R-HSA-69275
Hedgehog 'on' state R-HSA-5632684
Mitotic Anaphase R-HSA-68882
Generic Transcription Pathway R-HSA-212436
Regulation of PTEN stability and activity R-HSA-8948751
KEAP1-NFE2L2 pathway R-HSA-9755511
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
Asymmetric localization of PCP proteins R-HSA-4608870
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by NOTCH R-HSA-157118
Metabolism R-HSA-1430728
Cellular response to chemical stress R-HSA-9711123
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by WNT R-HSA-195721
Regulation of mitotic cell cycle R-HSA-453276
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Switching of origins to a post-replicative state R-HSA-69052
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
Developmental Biology R-HSA-1266738
Synthesis of DNA R-HSA-69239
PCP/CE pathway R-HSA-4086400
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S Transition R-HSA-69206
Antigen processing-Cross presentation R-HSA-1236975
Class I MHC mediated antigen processing & presentation R-HSA-983169
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
M Phase R-HSA-68886
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Downstream TCR signaling R-HSA-202424
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent DNA Damage Response R-HSA-69610
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
Cyclin E associated events during G1/S transition R-HSA-69202
Deubiquitination R-HSA-5688426
G1/S DNA Damage Checkpoints R-HSA-69615
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of RAS by GAPs R-HSA-5658442
UCH proteinases R-HSA-5689603
Infectious disease R-HSA-5663205
Neutrophil degranulation R-HSA-6798695
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ub-specific processing proteases R-HSA-5689880
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK family signaling cascades R-HSA-5683057
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transport of small molecules R-HSA-382551
Hedgehog 'off' state R-HSA-5610787
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
C-type lectin receptors (CLRs) R-HSA-5621481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stress R-HSA-2262752
Degradation of beta-catenin by the destruction complex R-HSA-195253
Axon guidance R-HSA-422475
Interleukin-1 family signaling R-HSA-446652
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Adaptive Immune System R-HSA-1280218
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of DVL R-HSA-4641258
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by NOTCH4 R-HSA-9013694
MAPK1/MAPK3 signaling R-HSA-5684996
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ER-Phagosome pathway R-HSA-1236974
ABC-family proteins mediated transport R-HSA-382556
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of AXIN R-HSA-4641257
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of polyamines R-HSA-351202
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Metaphase and Anaphase R-HSA-2555396
HIV Infection R-HSA-162906
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Activation of NF-kappaB in B cells R-HSA-1169091
G2/M Checkpoints R-HSA-69481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PIP3 activates AKT signaling R-HSA-1257604
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Beta-catenin independent WNT signaling R-HSA-3858494
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by ROBO receptors R-HSA-376176
Mitotic G1 phase and G1/S transition R-HSA-453279
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by WNT R-HSA-195721
MAPK family signaling cascades R-HSA-5683057
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX3 R-HSA-8878159
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Degradation of DVL R-HSA-4641258
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle, Mitotic R-HSA-69278
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Disease R-HSA-1643685
Axon guidance R-HSA-422475
RAF/MAP kinase cascade R-HSA-5673001
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog ligand biogenesis R-HSA-5358346
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
Hedgehog 'on' state R-HSA-5632684
Nuclear events mediated by NFE2L2 R-HSA-9759194
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Cyclin E associated events during G1/S transition R-HSA-69202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RUNX2 expression and activity R-HSA-8939902
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX1 R-HSA-8878171
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants are degraded by ERAD R-HSA-5362768
Signal Transduction R-HSA-162582
G1/S Transition R-HSA-69206
Deubiquitination R-HSA-5688426
Developmental Biology R-HSA-1266738
Interleukin-1 family signaling R-HSA-446652
ABC transporter disorders R-HSA-5619084
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
C-type lectin receptors (CLRs) R-HSA-5621481
G2/M Transition R-HSA-69275
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of RAS by GAPs R-HSA-5658442
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Immune System R-HSA-168256
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of AXIN R-HSA-4641257
Synthesis of DNA R-HSA-69239
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
FCERI mediated NF-kB activation R-HSA-2871837
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Signaling by Interleukins R-HSA-449147
Neddylation R-HSA-8951664
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic G1 phase and G1/S transition R-HSA-453279
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Neutrophil degranulation R-HSA-6798695
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Apoptosis R-HSA-109581
Signaling by NOTCH4 R-HSA-9013694
Nervous system development R-HSA-9675108
Mitotic Anaphase R-HSA-68882
HIV Infection R-HSA-162906
Orc1 removal from chromatin R-HSA-68949
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of RNA R-HSA-8953854
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by ROBO receptors R-HSA-376176
Infectious disease R-HSA-5663205
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of polyamines R-HSA-351202
Cell Cycle R-HSA-1640170
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
S Phase R-HSA-69242
Ub-specific processing proteases R-HSA-5689880
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Separation of Sister Chromatids R-HSA-2467813
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Programmed Cell Death R-HSA-5357801
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RUNX3 expression and activity R-HSA-8941858
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
PCP/CE pathway R-HSA-4086400
G1/S DNA Damage Checkpoints R-HSA-69615
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK6/MAPK4 signaling R-HSA-5687128
M Phase R-HSA-68886
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Vif-mediated degradation of APOBEC3G R-HSA-180585
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI1 by the proteasome R-HSA-5610780
Disorders of transmembrane transporters R-HSA-5619115
Degradation of beta-catenin by the destruction complex R-HSA-195253
ER-Phagosome pathway R-HSA-1236974
Transport of small molecules R-HSA-382551
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TCF dependent signaling in response to WNT R-HSA-201681
Antigen processing-Cross presentation R-HSA-1236975
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G2/M Checkpoints R-HSA-69481
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
Interleukin-1 family signaling R-HSA-446652
Antigen processing-Cross presentation R-HSA-1236975
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PIP3 activates AKT signaling R-HSA-1257604
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
HIV Infection R-HSA-162906
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'on' state R-HSA-5632684
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
Regulation of Apoptosis R-HSA-169911
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
PCP/CE pathway R-HSA-4086400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S Transition R-HSA-69206
Immune System R-HSA-168256
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
Infectious disease R-HSA-5663205
Transport of small molecules R-HSA-382551
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular response to hypoxia R-HSA-1234174
Switching of origins to a post-replicative state R-HSA-69052
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent DNA Damage Response R-HSA-69610
Transcriptional regulation by RUNX3 R-HSA-8878159
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of RAS by GAPs R-HSA-5658442
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Synthesis of DNA R-HSA-69239
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
Hh mutants abrogate ligand secretion R-HSA-5387390
TCR signaling R-HSA-202403
Metabolism R-HSA-1430728
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Anaphase R-HSA-68882
Metabolism of polyamines R-HSA-351202
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular responses to stimuli R-HSA-8953897
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Deubiquitination R-HSA-5688426
Activation of NF-kappaB in B cells R-HSA-1169091
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Defective CFTR causes cystic fibrosis R-HSA-5678895
Adaptive Immune System R-HSA-1280218
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Assembly of the pre-replicative complex R-HSA-68867
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
Mitotic G1 phase and G1/S transition R-HSA-453279
Disorders of transmembrane transporters R-HSA-5619115
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by ROBO receptors R-HSA-376176
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of AXIN R-HSA-4641257
Hedgehog ligand biogenesis R-HSA-5358346
M Phase R-HSA-68886
Cellular response to chemical stress R-HSA-9711123
TCF dependent signaling in response to WNT R-HSA-201681
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle Checkpoints R-HSA-69620
Neddylation R-HSA-8951664
Hedgehog 'off' state R-HSA-5610787
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of PTEN stability and activity R-HSA-8948751
Transcriptional regulation by RUNX2 R-HSA-8878166
Vif-mediated degradation of APOBEC3G R-HSA-180585
MAPK6/MAPK4 signaling R-HSA-5687128
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 signaling R-HSA-9020702
Nervous system development R-HSA-9675108
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
C-type lectin receptors (CLRs) R-HSA-5621481
Developmental Biology R-HSA-1266738
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by NOTCH R-HSA-157118
Cell Cycle R-HSA-1640170
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
Apoptosis R-HSA-109581
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by Interleukins R-HSA-449147
DNA Replication Pre-Initiation R-HSA-69002
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
ER-Phagosome pathway R-HSA-1236974
Cell Cycle, Mitotic R-HSA-69278
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
KEAP1-NFE2L2 pathway R-HSA-9755511
Generic Transcription Pathway R-HSA-212436
Degradation of GLI2 by the proteasome R-HSA-5610783
Post-translational protein modification R-HSA-597592
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by WNT R-HSA-195721
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of RNA R-HSA-8953854
Signaling by NOTCH4 R-HSA-9013694
ABC-family proteins mediated transport R-HSA-382556
Host Interactions of HIV factors R-HSA-162909
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of proteins R-HSA-392499
Axon guidance R-HSA-422475
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of RUNX3 expression and activity R-HSA-8941858
Immune System R-HSA-168256
Signaling by NOTCH R-HSA-157118
Degradation of GLI2 by the proteasome R-HSA-5610783
TCR signaling R-HSA-202403
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication R-HSA-69306
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Transition R-HSA-69275
Axon guidance R-HSA-422475
Cell Cycle R-HSA-1640170
Signaling by Hedgehog R-HSA-5358351
Mitotic Anaphase R-HSA-68882
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Downstream TCR signaling R-HSA-202424
ABC-family proteins mediated transport R-HSA-382556
HIV Infection R-HSA-162906
Cell Cycle, Mitotic R-HSA-69278
Separation of Sister Chromatids R-HSA-2467813
S Phase R-HSA-69242
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
Adaptive Immune System R-HSA-1280218
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular response to hypoxia R-HSA-1234174
Hh mutants abrogate ligand secretion R-HSA-5387390
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent DNA Damage Response R-HSA-69610
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Gene expression (Transcription) R-HSA-74160
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
DNA Replication Pre-Initiation R-HSA-69002
Interleukin-1 family signaling R-HSA-446652
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ub-specific processing proteases R-HSA-5689880
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic G2-G2/M phases R-HSA-453274
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cyclin E associated events during G1/S transition R-HSA-69202
Switching of origins to a post-replicative state R-HSA-69052
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
KEAP1-NFE2L2 pathway R-HSA-9755511
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH4 R-HSA-9013694
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Post-translational protein modification R-HSA-597592
Nervous system development R-HSA-9675108
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle Checkpoints R-HSA-69620
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signal Transduction R-HSA-162582
Regulation of RAS by GAPs R-HSA-5658442
TCF dependent signaling in response to WNT R-HSA-201681
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 signaling R-HSA-9020702
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Metaphase and Anaphase R-HSA-2555396
G2/M Checkpoints R-HSA-69481
Deubiquitination R-HSA-5688426
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX3 R-HSA-8878159
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by ROBO receptors R-HSA-376176
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Programmed Cell Death R-HSA-5357801
Hh mutants are degraded by ERAD R-HSA-5362768
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
FCERI mediated NF-kB activation R-HSA-2871837
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PIP3 activates AKT signaling R-HSA-1257604
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Regulation of Apoptosis R-HSA-169911
Orc1 removal from chromatin R-HSA-68949
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
Activation of NF-kappaB in B cells R-HSA-1169091
Apoptosis R-HSA-109581
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of GLI1 by the proteasome R-HSA-5610780
M Phase R-HSA-68886
Defective CFTR causes cystic fibrosis R-HSA-5678895
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RUNX2 expression and activity R-HSA-8939902
Vif-mediated degradation of APOBEC3G R-HSA-180585
Stabilization of p53 R-HSA-69541
Hedgehog 'on' state R-HSA-5632684
Assembly of the pre-replicative complex R-HSA-68867
Neddylation R-HSA-8951664
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by WNT R-HSA-195721
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
Metabolism of polyamines R-HSA-351202
Neutrophil degranulation R-HSA-6798695
ABC transporter disorders R-HSA-5619084
MAPK family signaling cascades R-HSA-5683057
Hedgehog 'off' state R-HSA-5610787
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vpu mediated degradation of CD4 R-HSA-180534
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by Interleukins R-HSA-449147
Degradation of AXIN R-HSA-4641257
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by the B Cell Receptor (BCR) R-HSA-983705
S Phase R-HSA-69242
DNA Replication Pre-Initiation R-HSA-69002
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'on' state R-HSA-5632684
Regulation of PTEN stability and activity R-HSA-8948751
Vpu mediated degradation of CD4 R-HSA-180534
Generic Transcription Pathway R-HSA-212436
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by Hedgehog R-HSA-5358351
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transcriptional regulation by RUNX3 R-HSA-8878159
MAPK1/MAPK3 signaling R-HSA-5684996
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
HIV Infection R-HSA-162906
Gene expression (Transcription) R-HSA-74160
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
Regulation of mitotic cell cycle R-HSA-453276
Signaling by WNT R-HSA-195721
Cellular response to chemical stress R-HSA-9711123
Apoptosis R-HSA-109581
Metabolism of RNA R-HSA-8953854
PIP3 activates AKT signaling R-HSA-1257604
TCF dependent signaling in response to WNT R-HSA-201681
Orc1 removal from chromatin R-HSA-68949
Transport of small molecules R-HSA-382551
Programmed Cell Death R-HSA-5357801
Interleukin-1 signaling R-HSA-9020702
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Assembly of the pre-replicative complex R-HSA-68867
Signaling by NOTCH4 R-HSA-9013694
Mitotic Metaphase and Anaphase R-HSA-2555396
Interleukin-1 family signaling R-HSA-446652
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
ABC transporter disorders R-HSA-5619084
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated NF-kB activation R-HSA-2871837
Separation of Sister Chromatids R-HSA-2467813
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G1/S Transition R-HSA-69206
Cell Cycle Checkpoints R-HSA-69620
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of amino acids and derivatives R-HSA-71291
Disorders of transmembrane transporters R-HSA-5619115
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
Neutrophil degranulation R-HSA-6798695
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of DVL R-HSA-4641258
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Downstream TCR signaling R-HSA-202424
RAF/MAP kinase cascade R-HSA-5673001
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular responses to stress R-HSA-2262752
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism of polyamines R-HSA-351202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Axon guidance R-HSA-422475
PCP/CE pathway R-HSA-4086400
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to hypoxia R-HSA-1234174
Immune System R-HSA-168256
G2/M Checkpoints R-HSA-69481
Regulation of RAS by GAPs R-HSA-5658442
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Disease R-HSA-1643685
Hedgehog ligand biogenesis R-HSA-5358346
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Post-translational protein modification R-HSA-597592
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Deubiquitination R-HSA-5688426
Degradation of GLI2 by the proteasome R-HSA-5610783
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Vif-mediated degradation of APOBEC3G R-HSA-180585
Host Interactions of HIV factors R-HSA-162909
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism R-HSA-1430728
Adaptive Immune System R-HSA-1280218
Intracellular signaling by second messengers R-HSA-9006925
Regulation of Apoptosis R-HSA-169911
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Developmental Biology R-HSA-1266738
G1/S DNA Damage Checkpoints R-HSA-69615
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication R-HSA-69306
Nervous system development R-HSA-9675108
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signal Transduction R-HSA-162582
ER-Phagosome pathway R-HSA-1236974
p53-Independent DNA Damage Response R-HSA-69610
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RUNX2 expression and activity R-HSA-8939902
UCH proteinases R-HSA-5689603
Metabolism of proteins R-HSA-392499
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCR signaling R-HSA-202403
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by ROBO receptors R-HSA-376176
Signaling by Interleukins R-HSA-449147
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK family signaling cascades R-HSA-5683057
Cell Cycle, Mitotic R-HSA-69278
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ABC-family proteins mediated transport R-HSA-382556
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of NF-kappaB in B cells R-HSA-1169091
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Beta-catenin independent WNT signaling R-HSA-3858494
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX1 R-HSA-8878171
RNA Polymerase II Transcription R-HSA-73857
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX2 R-HSA-8878166

Expression Atlas ENSG00000136930
NCBI gene (formerly Entrezgene) 5695
GeneCards 9544
HGNC Symbol HGNC:9544
MIM gene 604030
UniProtKB Gene Name Q99436
WikiGene 5695
Gene: PSMA6
Ensembl ID : ENSG00000100902
Description: proteasome 20S subunit alpha 6
Gene Synonyms: IOTA,MGC22756,MGC2333,MGC23846,P27K,PROS27
6 APIs:
275 Possible Orthologues:

Disease R-HSA-1643685
Stabilization of p53 R-HSA-69541
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
Adaptive Immune System R-HSA-1280218
Signaling by ROBO receptors R-HSA-376176
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
Assembly of the pre-replicative complex R-HSA-68867
ABC-family proteins mediated transport R-HSA-382556
Regulation of mitotic cell cycle R-HSA-453276
Nervous system development R-HSA-9675108
PTEN Regulation R-HSA-6807070
Separation of Sister Chromatids R-HSA-2467813
G1/S Transition R-HSA-69206
Downstream TCR signaling R-HSA-202424
DNA Replication Pre-Initiation R-HSA-69002
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
FCERI mediated NF-kB activation R-HSA-2871837
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Generic Transcription Pathway R-HSA-212436
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by WNT R-HSA-195721
PCP/CE pathway R-HSA-4086400
Cell Cycle Checkpoints R-HSA-69620
Vif-mediated degradation of APOBEC3G R-HSA-180585
Infectious disease R-HSA-5663205
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stimuli R-HSA-8953897
Antigen processing-Cross presentation R-HSA-1236975
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of RUNX2 expression and activity R-HSA-8939902
Interleukin-1 signaling R-HSA-9020702
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX3 R-HSA-8878159
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK6/MAPK4 signaling R-HSA-5687128
ER-Phagosome pathway R-HSA-1236974
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Post-translational protein modification R-HSA-597592
DNA Replication R-HSA-69306
RAF/MAP kinase cascade R-HSA-5673001
Degradation of AXIN R-HSA-4641257
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Interleukins R-HSA-449147
MAPK family signaling cascades R-HSA-5683057
Metabolism R-HSA-1430728
Disease R-HSA-1643685
G2/M Transition R-HSA-69275
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Immune System R-HSA-168256
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle, Mitotic R-HSA-69278
Innate Immune System R-HSA-168249
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of RUNX3 expression and activity R-HSA-8941858
Vpu mediated degradation of CD4 R-HSA-180534
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RAS by GAPs R-HSA-5658442
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of Apoptosis R-HSA-169911
Hedgehog 'off' state R-HSA-5610787
Developmental Biology R-HSA-1266738
Synthesis of DNA R-HSA-69239
Programmed Cell Death R-HSA-5357801
Cellular responses to stress R-HSA-2262752
Signaling by Hedgehog R-HSA-5358351
Activation of NF-kappaB in B cells R-HSA-1169091
Ub-specific processing proteases R-HSA-5689880
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic G1 phase and G1/S transition R-HSA-453279
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism of amino acids and derivatives R-HSA-71291
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hh mutants abrogate ligand secretion R-HSA-5387390
Hh mutants are degraded by ERAD R-HSA-5362768
Apoptosis R-HSA-109581
ABC transporter disorders R-HSA-5619084
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of GLI1 by the proteasome R-HSA-5610780
M Phase R-HSA-68886
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of RNA R-HSA-8953854
p53-Independent DNA Damage Response R-HSA-69610
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Checkpoints R-HSA-69481
Metabolism of polyamines R-HSA-351202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
Transport of small molecules R-HSA-382551
HIV Infection R-HSA-162906
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
TCF dependent signaling in response to WNT R-HSA-201681
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic Anaphase R-HSA-68882
TCR signaling R-HSA-202403
Interleukin-1 family signaling R-HSA-446652
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to chemical stress R-HSA-9711123
Cell Cycle R-HSA-1640170
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
p53-Dependent G1 DNA Damage Response R-HSA-69563
Deubiquitination R-HSA-5688426
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH4 R-HSA-9013694
Regulation of PTEN stability and activity R-HSA-8948751
Disorders of transmembrane transporters R-HSA-5619115
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of proteins R-HSA-392499
Hedgehog 'on' state R-HSA-5632684
Orc1 removal from chromatin R-HSA-68949
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by NOTCH R-HSA-157118
UCH proteinases R-HSA-5689603
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic G1 phase and G1/S transition R-HSA-453279
Nervous system development R-HSA-9675108
DNA Replication Pre-Initiation R-HSA-69002
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
DNA Replication R-HSA-69306
Hh mutants are degraded by ERAD R-HSA-5362768
Interleukin-1 family signaling R-HSA-446652
Cytokine Signaling in Immune system R-HSA-1280215
G1/S Transition R-HSA-69206
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular response to hypoxia R-HSA-1234174
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of proteins R-HSA-392499
Synthesis of DNA R-HSA-69239
Mitotic Metaphase and Anaphase R-HSA-2555396
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog 'off' state R-HSA-5610787
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of DVL R-HSA-4641258
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle, Mitotic R-HSA-69278
Metabolism R-HSA-1430728
Post-translational protein modification R-HSA-597592
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of PTEN stability and activity R-HSA-8948751
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1 DNA Damage Response R-HSA-69563
Asymmetric localization of PCP proteins R-HSA-4608870
Adaptive Immune System R-HSA-1280218
Generic Transcription Pathway R-HSA-212436
Signaling by Interleukins R-HSA-449147
Hedgehog 'on' state R-HSA-5632684
Downstream TCR signaling R-HSA-202424
HIV Infection R-HSA-162906
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of polyamines R-HSA-351202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular response to chemical stress R-HSA-9711123
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of mitotic cell cycle R-HSA-453276
Vpu mediated degradation of CD4 R-HSA-180534
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
RAF/MAP kinase cascade R-HSA-5673001
Transport of small molecules R-HSA-382551
Intracellular signaling by second messengers R-HSA-9006925
MAPK family signaling cascades R-HSA-5683057
Immune System R-HSA-168256
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Gene expression (Transcription) R-HSA-74160
PCP/CE pathway R-HSA-4086400
Cellular responses to stimuli R-HSA-8953897
Cyclin E associated events during G1/S transition R-HSA-69202
TCF dependent signaling in response to WNT R-HSA-201681
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RUNX2 expression and activity R-HSA-8939902
Disease R-HSA-1643685
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of GLI2 by the proteasome R-HSA-5610783
Axon guidance R-HSA-422475
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by ROBO receptors R-HSA-376176
Cell Cycle R-HSA-1640170
Programmed Cell Death R-HSA-5357801
Nuclear events mediated by NFE2L2 R-HSA-9759194
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of AXIN R-HSA-4641257
Transcriptional regulation by RUNX2 R-HSA-8878166
Vif-mediated degradation of APOBEC3G R-HSA-180585
M Phase R-HSA-68886
Orc1 removal from chromatin R-HSA-68949
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TCR signaling R-HSA-202403
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH4 R-HSA-9013694
ABC-family proteins mediated transport R-HSA-382556
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
ABC transporter disorders R-HSA-5619084
Defective CFTR causes cystic fibrosis R-HSA-5678895
Assembly of the pre-replicative complex R-HSA-68867
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX3 expression and activity R-HSA-8941858
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Developmental Biology R-HSA-1266738
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX3 R-HSA-8878159
Stabilization of p53 R-HSA-69541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of beta-catenin by the destruction complex R-HSA-195253
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RNA Polymerase II Transcription R-HSA-73857
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH R-HSA-157118
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signal Transduction R-HSA-162582
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
Deubiquitination R-HSA-5688426
G2/M Checkpoints R-HSA-69481
Cellular responses to stress R-HSA-2262752
Separation of Sister Chromatids R-HSA-2467813
Mitotic G2-G2/M phases R-HSA-453274
Regulation of Apoptosis R-HSA-169911
Disorders of transmembrane transporters R-HSA-5619115
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
Signaling by Hedgehog R-HSA-5358351
ER-Phagosome pathway R-HSA-1236974
PIP3 activates AKT signaling R-HSA-1257604
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PTEN Regulation R-HSA-6807070
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism of RNA R-HSA-8953854
KEAP1-NFE2L2 pathway R-HSA-9755511
Apoptosis R-HSA-109581
Cell Cycle Checkpoints R-HSA-69620
FCERI mediated NF-kB activation R-HSA-2871837
S Phase R-HSA-69242
Innate Immune System R-HSA-168249
UCH proteinases R-HSA-5689603
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
S Phase R-HSA-69242
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Interleukins R-HSA-449147
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle Checkpoints R-HSA-69620
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cellular response to chemical stress R-HSA-9711123
Degradation of beta-catenin by the destruction complex R-HSA-195253
Apoptosis R-HSA-109581
Cell Cycle R-HSA-1640170
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Metabolism of proteins R-HSA-392499
Signaling by Hedgehog R-HSA-5358351
M Phase R-HSA-68886
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RAF/MAP kinase cascade R-HSA-5673001
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX2 R-HSA-8878166
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stimuli R-HSA-8953897
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
DNA Replication R-HSA-69306
Disorders of transmembrane transporters R-HSA-5619115
Transcriptional regulation by RUNX3 R-HSA-8878159
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of polyamines R-HSA-351202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PTEN Regulation R-HSA-6807070
Regulation of mitotic cell cycle R-HSA-453276
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
HIV Infection R-HSA-162906
TCR signaling R-HSA-202403
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of AXIN R-HSA-4641257
Cellular response to hypoxia R-HSA-1234174
Regulation of RUNX3 expression and activity R-HSA-8941858
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Adaptive Immune System R-HSA-1280218
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI1 by the proteasome R-HSA-5610780
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of amino acids and derivatives R-HSA-71291
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Checkpoints R-HSA-69481
Hh mutants are degraded by ERAD R-HSA-5362768
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH4 R-HSA-9013694
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Programmed Cell Death R-HSA-5357801
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
KEAP1-NFE2L2 pathway R-HSA-9755511
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Mitotic Anaphase R-HSA-68882
Regulation of Apoptosis R-HSA-169911
Hedgehog 'on' state R-HSA-5632684
Antigen processing-Cross presentation R-HSA-1236975
G2/M Transition R-HSA-69275
Orc1 removal from chromatin R-HSA-68949
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G1/S Transition R-HSA-69206
Gene expression (Transcription) R-HSA-74160
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of GLI2 by the proteasome R-HSA-5610783
MAPK family signaling cascades R-HSA-5683057
Post-translational protein modification R-HSA-597592
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
Cellular responses to stress R-HSA-2262752
Ub-specific processing proteases R-HSA-5689880
Metabolism of RNA R-HSA-8953854
p53-Independent DNA Damage Response R-HSA-69610
Synthesis of DNA R-HSA-69239
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic Metaphase and Anaphase R-HSA-2555396
Axon guidance R-HSA-422475
Hedgehog 'off' state R-HSA-5610787
DNA Replication Pre-Initiation R-HSA-69002
Metabolism R-HSA-1430728
Vif-mediated degradation of APOBEC3G R-HSA-180585
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 family signaling R-HSA-446652
Mitotic G2-G2/M phases R-HSA-453274
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle, Mitotic R-HSA-69278
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Intracellular signaling by second messengers R-HSA-9006925
Transport of small molecules R-HSA-382551
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Deubiquitination R-HSA-5688426
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional regulation by RUNX1 R-HSA-8878171
Signal Transduction R-HSA-162582
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of NF-kappaB in B cells R-HSA-1169091
Negative regulation of NOTCH4 signaling R-HSA-9604323
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 signaling R-HSA-9020702
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ABC transporter disorders R-HSA-5619084
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH R-HSA-157118
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Hedgehog ligand biogenesis R-HSA-5358346
Separation of Sister Chromatids R-HSA-2467813
Degradation of DVL R-HSA-4641258
Regulation of RUNX2 expression and activity R-HSA-8939902
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream TCR signaling R-HSA-202424
PCP/CE pathway R-HSA-4086400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
Host Interactions of HIV factors R-HSA-162909
Signaling by WNT R-HSA-195721
Cyclin E associated events during G1/S transition R-HSA-69202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hh mutants abrogate ligand secretion R-HSA-5387390
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
M Phase R-HSA-68886
Metabolism R-HSA-1430728
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stress R-HSA-2262752
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'on' state R-HSA-5632684
DNA Replication R-HSA-69306
Synthesis of DNA R-HSA-69239
p53-Dependent G1 DNA Damage Response R-HSA-69563
CLEC7A (Dectin-1) signaling R-HSA-5607764
Stabilization of p53 R-HSA-69541
Assembly of the pre-replicative complex R-HSA-68867
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to hypoxia R-HSA-1234174
Cell Cycle R-HSA-1640170
ER-Phagosome pathway R-HSA-1236974
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
Hh mutants abrogate ligand secretion R-HSA-5387390
Disorders of transmembrane transporters R-HSA-5619115
Post-translational protein modification R-HSA-597592
Cyclin E associated events during G1/S transition R-HSA-69202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Adaptive Immune System R-HSA-1280218
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hedgehog ligand biogenesis R-HSA-5358346
TCF dependent signaling in response to WNT R-HSA-201681
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
Downstream TCR signaling R-HSA-202424
p53-Independent DNA Damage Response R-HSA-69610
Mitotic G2-G2/M phases R-HSA-453274
Degradation of beta-catenin by the destruction complex R-HSA-195253
Beta-catenin independent WNT signaling R-HSA-3858494
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of DVL R-HSA-4641258
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Asymmetric localization of PCP proteins R-HSA-4608870
Generic Transcription Pathway R-HSA-212436
ABC-family proteins mediated transport R-HSA-382556
Switching of origins to a post-replicative state R-HSA-69052
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
UCH proteinases R-HSA-5689603
Signaling by NOTCH4 R-HSA-9013694
Activation of NF-kappaB in B cells R-HSA-1169091
Developmental Biology R-HSA-1266738
Signaling by ROBO receptors R-HSA-376176
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G1 phase and G1/S transition R-HSA-453279
Interleukin-1 family signaling R-HSA-446652
Metabolism of proteins R-HSA-392499
Neddylation R-HSA-8951664
Cell Cycle, Mitotic R-HSA-69278
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants are degraded by ERAD R-HSA-5362768
PIP3 activates AKT signaling R-HSA-1257604
Programmed Cell Death R-HSA-5357801
HIV Infection R-HSA-162906
Axon guidance R-HSA-422475
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog 'off' state R-HSA-5610787
Signaling by WNT R-HSA-195721
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Deubiquitination R-HSA-5688426
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by Hedgehog R-HSA-5358351
RAF/MAP kinase cascade R-HSA-5673001
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Ub-specific processing proteases R-HSA-5689880
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Separation of Sister Chromatids R-HSA-2467813
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G1/S Transition R-HSA-69206
Metabolism of RNA R-HSA-8953854
Transport of small molecules R-HSA-382551
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
TCR signaling R-HSA-202403
Cellular responses to stimuli R-HSA-8953897
Mitotic Metaphase and Anaphase R-HSA-2555396
PTEN Regulation R-HSA-6807070
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G2/M Transition R-HSA-69275
Antigen processing-Cross presentation R-HSA-1236975
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
G2/M Checkpoints R-HSA-69481
Cellular response to chemical stress R-HSA-9711123
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Defective CFTR causes cystic fibrosis R-HSA-5678895
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX1 R-HSA-8878171
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of polyamines R-HSA-351202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of RAS by GAPs R-HSA-5658442
Disease R-HSA-1643685
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mitotic cell cycle R-HSA-453276
FCERI mediated NF-kB activation R-HSA-2871837
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of amino acids and derivatives R-HSA-71291
MAPK family signaling cascades R-HSA-5683057
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX2 R-HSA-8878166
Host Interactions of HIV factors R-HSA-162909
ABC transporter disorders R-HSA-5619084
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Class I MHC mediated antigen processing & presentation R-HSA-983169
Orc1 removal from chromatin R-HSA-68949
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Negative regulation of NOTCH4 signaling R-HSA-9604323
Mitotic Anaphase R-HSA-68882
Signaling by Interleukins R-HSA-449147
C-type lectin receptors (CLRs) R-HSA-5621481
Gene expression (Transcription) R-HSA-74160
Apoptosis R-HSA-109581
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK1/MAPK3 signaling R-HSA-5684996
RNA Polymerase II Transcription R-HSA-73857
Mitotic G1 phase and G1/S transition R-HSA-453279
Neddylation R-HSA-8951664
TCR signaling R-HSA-202403
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
ER-Phagosome pathway R-HSA-1236974
G2/M Transition R-HSA-69275
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PCP/CE pathway R-HSA-4086400
Degradation of AXIN R-HSA-4641257
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'on' state R-HSA-5632684
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transcriptional regulation by RUNX3 R-HSA-8878159
p53-Independent DNA Damage Response R-HSA-69610
Activation of NF-kappaB in B cells R-HSA-1169091
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Hedgehog R-HSA-5358351
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of mitotic cell cycle R-HSA-453276
Downstream TCR signaling R-HSA-202424
Beta-catenin independent WNT signaling R-HSA-3858494
Nervous system development R-HSA-9675108
MAPK6/MAPK4 signaling R-HSA-5687128
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of polyamines R-HSA-351202
Signaling by NOTCH R-HSA-157118
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
Separation of Sister Chromatids R-HSA-2467813
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Antigen processing-Cross presentation R-HSA-1236975
Orc1 removal from chromatin R-HSA-68949
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by ROBO receptors R-HSA-376176
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
Class I MHC mediated antigen processing & presentation R-HSA-983169
ABC-family proteins mediated transport R-HSA-382556
S Phase R-HSA-69242
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PIP3 activates AKT signaling R-HSA-1257604
Hh mutants abrogate ligand secretion R-HSA-5387390
Switching of origins to a post-replicative state R-HSA-69052
G1/S DNA Damage Checkpoints R-HSA-69615
Assembly of the pre-replicative complex R-HSA-68867
Stabilization of p53 R-HSA-69541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Infectious disease R-HSA-5663205
ABC transporter disorders R-HSA-5619084
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI2 by the proteasome R-HSA-5610783
RNA Polymerase II Transcription R-HSA-73857
Regulation of RAS by GAPs R-HSA-5658442
Cellular response to hypoxia R-HSA-1234174
Signal Transduction R-HSA-162582
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by WNT R-HSA-195721
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic G2-G2/M phases R-HSA-453274
Regulation of PTEN stability and activity R-HSA-8948751
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of RUNX2 expression and activity R-HSA-8939902
Developmental Biology R-HSA-1266738
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
Cell Cycle, Mitotic R-HSA-69278
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
Transport of small molecules R-HSA-382551
RAF/MAP kinase cascade R-HSA-5673001
G2/M Checkpoints R-HSA-69481
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX2 R-HSA-8878166
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of proteins R-HSA-392499
Interleukin-1 signaling R-HSA-9020702
Vif-mediated degradation of APOBEC3G R-HSA-180585
HIV Infection R-HSA-162906
Degradation of GLI1 by the proteasome R-HSA-5610780
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Host Interactions of HIV factors R-HSA-162909
Deubiquitination R-HSA-5688426
G1/S Transition R-HSA-69206
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of RNA R-HSA-8953854
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hedgehog 'off' state R-HSA-5610787
Programmed Cell Death R-HSA-5357801
UCH proteinases R-HSA-5689603
Synthesis of DNA R-HSA-69239
Hedgehog ligand biogenesis R-HSA-5358346
p53-Dependent G1 DNA Damage Response R-HSA-69563
Post-translational protein modification R-HSA-597592
Immune System R-HSA-168256
Apoptosis R-HSA-109581
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of amino acids and derivatives R-HSA-71291
Cytokine Signaling in Immune system R-HSA-1280215
DNA Replication R-HSA-69306
PTEN Regulation R-HSA-6807070
Cellular response to chemical stress R-HSA-9711123
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stress R-HSA-2262752
Regulation of RUNX3 expression and activity R-HSA-8941858
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
M Phase R-HSA-68886
Signaling by NOTCH4 R-HSA-9013694
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK family signaling cascades R-HSA-5683057
Disorders of transmembrane transporters R-HSA-5619115
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Stabilization of p53 R-HSA-69541
Hh mutants are degraded by ERAD R-HSA-5362768
G1/S Transition R-HSA-69206
Programmed Cell Death R-HSA-5357801
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mitotic cell cycle R-HSA-453276
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent DNA Damage Response R-HSA-69610
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
DNA Replication R-HSA-69306
Infectious disease R-HSA-5663205
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stimuli R-HSA-8953897
Transport of small molecules R-HSA-382551
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
Regulation of RUNX3 expression and activity R-HSA-8941858
Synthesis of DNA R-HSA-69239
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of Apoptosis R-HSA-169911
Deubiquitination R-HSA-5688426
Switching of origins to a post-replicative state R-HSA-69052
Signaling by Interleukins R-HSA-449147
Signaling by NOTCH R-HSA-157118
MAPK family signaling cascades R-HSA-5683057
G1/S DNA Damage Checkpoints R-HSA-69615
RAF/MAP kinase cascade R-HSA-5673001
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular responses to stress R-HSA-2262752
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin E associated events during G1/S transition R-HSA-69202
Developmental Biology R-HSA-1266738
Downstream TCR signaling R-HSA-202424
M Phase R-HSA-68886
Mitotic G1 phase and G1/S transition R-HSA-453279
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nuclear events mediated by NFE2L2 R-HSA-9759194
RNA Polymerase II Transcription R-HSA-73857
Degradation of AXIN R-HSA-4641257
Degradation of GLI2 by the proteasome R-HSA-5610783
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Vpu mediated degradation of CD4 R-HSA-180534
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Hh mutants abrogate ligand secretion R-HSA-5387390
Cellular response to hypoxia R-HSA-1234174
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
S Phase R-HSA-69242
Mitotic G2-G2/M phases R-HSA-453274
Metabolism of RNA R-HSA-8953854
Degradation of beta-catenin by the destruction complex R-HSA-195253
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Host Interactions of HIV factors R-HSA-162909
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Disorders of transmembrane transporters R-HSA-5619115
Defective CFTR causes cystic fibrosis R-HSA-5678895
PCP/CE pathway R-HSA-4086400
G2/M Transition R-HSA-69275
Negative regulation of NOTCH4 signaling R-HSA-9604323
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
HIV Infection R-HSA-162906
Gene expression (Transcription) R-HSA-74160
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hedgehog 'on' state R-HSA-5632684
Metabolism of polyamines R-HSA-351202
Signal Transduction R-HSA-162582
Interleukin-1 signaling R-HSA-9020702
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic Metaphase and Anaphase R-HSA-2555396
DNA Replication Pre-Initiation R-HSA-69002
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Apoptosis R-HSA-109581
Hedgehog 'off' state R-HSA-5610787
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Ub-specific processing proteases R-HSA-5689880
Signaling by WNT R-HSA-195721
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH4 R-HSA-9013694
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Post-translational protein modification R-HSA-597592
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of DVL R-HSA-4641258
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
Cellular response to chemical stress R-HSA-9711123
Neddylation R-HSA-8951664
KEAP1-NFE2L2 pathway R-HSA-9755511
TCR signaling R-HSA-202403
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic Anaphase R-HSA-68882
MAPK1/MAPK3 signaling R-HSA-5684996
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 family signaling R-HSA-446652
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Immune System R-HSA-168256
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Antigen processing-Cross presentation R-HSA-1236975
ABC transporter disorders R-HSA-5619084
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Adaptive Immune System R-HSA-1280218
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Generic Transcription Pathway R-HSA-212436
Innate Immune System R-HSA-168249
Assembly of the pre-replicative complex R-HSA-68867
Class I MHC mediated antigen processing & presentation R-HSA-983169
Nervous system development R-HSA-9675108
Intracellular signaling by second messengers R-HSA-9006925
Vif-mediated degradation of APOBEC3G R-HSA-180585
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of amino acids and derivatives R-HSA-71291
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Axon guidance R-HSA-422475
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of proteins R-HSA-392499
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle R-HSA-1640170
G2/M Checkpoints R-HSA-69481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by WNT R-HSA-195721
Signaling by NOTCH R-HSA-157118
Regulation of RUNX2 expression and activity R-HSA-8939902
Developmental Biology R-HSA-1266738
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G1 phase and G1/S transition R-HSA-453279
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular responses to stimuli R-HSA-8953897
Cyclin E associated events during G1/S transition R-HSA-69202
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PCP/CE pathway R-HSA-4086400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream TCR signaling R-HSA-202424
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
RAF/MAP kinase cascade R-HSA-5673001
ABC-family proteins mediated transport R-HSA-382556
Degradation of GLI1 by the proteasome R-HSA-5610780
Orc1 removal from chromatin R-HSA-68949
TCR signaling R-HSA-202403
Cell Cycle, Mitotic R-HSA-69278
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
PIP3 activates AKT signaling R-HSA-1257604
HIV Infection R-HSA-162906
Hedgehog 'off' state R-HSA-5610787
Cell Cycle Checkpoints R-HSA-69620
ABC transporter disorders R-HSA-5619084
Metabolism of RNA R-HSA-8953854
Deubiquitination R-HSA-5688426
Infectious disease R-HSA-5663205
Ub-specific processing proteases R-HSA-5689880
Mitotic Metaphase and Anaphase R-HSA-2555396
Disorders of transmembrane transporters R-HSA-5619115
Stabilization of p53 R-HSA-69541
Mitotic G2-G2/M phases R-HSA-453274
Separation of Sister Chromatids R-HSA-2467813
Adaptive Immune System R-HSA-1280218
Hh mutants abrogate ligand secretion R-HSA-5387390
Transcriptional regulation by RUNX2 R-HSA-8878166
Generic Transcription Pathway R-HSA-212436
Mitotic Anaphase R-HSA-68882
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Host Interactions of HIV factors R-HSA-162909
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of beta-catenin by the destruction complex R-HSA-195253
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Dependent G1 DNA Damage Response R-HSA-69563
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog 'on' state R-HSA-5632684
Cytokine Signaling in Immune system R-HSA-1280215
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by Hedgehog R-HSA-5358351
MAPK family signaling cascades R-HSA-5683057
ER-Phagosome pathway R-HSA-1236974
Assembly of the pre-replicative complex R-HSA-68867
UCH proteinases R-HSA-5689603
G2/M Checkpoints R-HSA-69481
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of polyamines R-HSA-351202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Neddylation R-HSA-8951664
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX3 expression and activity R-HSA-8941858
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by NOTCH4 R-HSA-9013694
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
RNA Polymerase II Transcription R-HSA-73857
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of DVL R-HSA-4641258
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of amino acids and derivatives R-HSA-71291
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to chemical stress R-HSA-9711123
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hedgehog ligand biogenesis R-HSA-5358346
Activation of NF-kappaB in B cells R-HSA-1169091
Nervous system development R-HSA-9675108
Defective CFTR causes cystic fibrosis R-HSA-5678895
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G2/M Transition R-HSA-69275
G1/S Transition R-HSA-69206
Regulation of Apoptosis R-HSA-169911
Axon guidance R-HSA-422475
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Interleukin-1 signaling R-HSA-9020702
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RAS by GAPs R-HSA-5658442
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism R-HSA-1430728
Signal Transduction R-HSA-162582
Signaling by the B Cell Receptor (BCR) R-HSA-983705
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
Signaling by ROBO receptors R-HSA-376176
Synthesis of DNA R-HSA-69239
NIK-->noncanonical NF-kB signaling R-HSA-5676590
M Phase R-HSA-68886
Cell Cycle R-HSA-1640170
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of mitotic cell cycle R-HSA-453276
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Class I MHC mediated antigen processing & presentation R-HSA-983169
Transport of small molecules R-HSA-382551
Intracellular signaling by second messengers R-HSA-9006925
Cellular response to hypoxia R-HSA-1234174
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Signaling by Interleukins R-HSA-449147
Programmed Cell Death R-HSA-5357801
Asymmetric localization of PCP proteins R-HSA-4608870
Post-translational protein modification R-HSA-597592
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX3 R-HSA-8878159
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of AXIN R-HSA-4641257
Separation of Sister Chromatids R-HSA-2467813
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to chemical stress R-HSA-9711123
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-1 family signaling R-HSA-446652
Orc1 removal from chromatin R-HSA-68949
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of DVL R-HSA-4641258
TCR signaling R-HSA-202403
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of RUNX2 expression and activity R-HSA-8939902
Apoptosis R-HSA-109581
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of Apoptosis R-HSA-169911
Class I MHC mediated antigen processing & presentation R-HSA-983169
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
Regulation of PTEN stability and activity R-HSA-8948751
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Anaphase R-HSA-68882
Cytokine Signaling in Immune system R-HSA-1280215
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
PCP/CE pathway R-HSA-4086400
Host Interactions of HIV factors R-HSA-162909
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S DNA Damage Checkpoints R-HSA-69615
Switching of origins to a post-replicative state R-HSA-69052
G2/M Transition R-HSA-69275
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RNA Polymerase II Transcription R-HSA-73857
Metabolism of polyamines R-HSA-351202
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK family signaling cascades R-HSA-5683057
G1/S Transition R-HSA-69206
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent DNA Damage Response R-HSA-69610
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
Hedgehog 'off' state R-HSA-5610787
PTEN Regulation R-HSA-6807070
Disease R-HSA-1643685
Metabolism of amino acids and derivatives R-HSA-71291
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G2-G2/M phases R-HSA-453274
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of mitotic cell cycle R-HSA-453276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC-family proteins mediated transport R-HSA-382556
Generic Transcription Pathway R-HSA-212436
Intracellular signaling by second messengers R-HSA-9006925
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK6/MAPK4 signaling R-HSA-5687128
Cell Cycle, Mitotic R-HSA-69278
Post-translational protein modification R-HSA-597592
Cyclin E associated events during G1/S transition R-HSA-69202
Programmed Cell Death R-HSA-5357801
S Phase R-HSA-69242
ABC transporter disorders R-HSA-5619084
G2/M Checkpoints R-HSA-69481
Signaling by ROBO receptors R-HSA-376176
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX2 R-HSA-8878166
Asymmetric localization of PCP proteins R-HSA-4608870
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RAS by GAPs R-HSA-5658442
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI2 by the proteasome R-HSA-5610783
HIV Infection R-HSA-162906
Signaling by NOTCH4 R-HSA-9013694
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stress R-HSA-2262752
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Downstream TCR signaling R-HSA-202424
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular response to hypoxia R-HSA-1234174
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Innate Immune System R-HSA-168249
Metabolism R-HSA-1430728
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Infectious disease R-HSA-5663205
Stabilization of p53 R-HSA-69541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of RNA R-HSA-8953854
Metabolism of proteins R-HSA-392499
C-type lectin receptors (CLRs) R-HSA-5621481
M Phase R-HSA-68886
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signal Transduction R-HSA-162582
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle R-HSA-1640170
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stimuli R-HSA-8953897
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ub-specific processing proteases R-HSA-5689880
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Developmental Biology R-HSA-1266738
Synthesis of DNA R-HSA-69239
Signaling by WNT R-HSA-195721
ER-Phagosome pathway R-HSA-1236974
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Adaptive Immune System R-HSA-1280218
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Interleukins R-HSA-449147
Vif-mediated degradation of APOBEC3G R-HSA-180585
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Interleukin-1 signaling R-HSA-9020702
Assembly of the pre-replicative complex R-HSA-68867
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Immune System R-HSA-168256
Transport of small molecules R-HSA-382551
Hedgehog 'on' state R-HSA-5632684
Nervous system development R-HSA-9675108
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by NOTCH4 R-HSA-9013694
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of AXIN R-HSA-4641257
Host Interactions of HIV factors R-HSA-162909
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
M Phase R-HSA-68886
Switching of origins to a post-replicative state R-HSA-69052
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of GLI1 by the proteasome R-HSA-5610780
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Disorders of transmembrane transporters R-HSA-5619115
Regulation of RUNX3 expression and activity R-HSA-8941858
Antigen processing-Cross presentation R-HSA-1236975
MAPK6/MAPK4 signaling R-HSA-5687128
Stabilization of p53 R-HSA-69541
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'on' state R-HSA-5632684
Programmed Cell Death R-HSA-5357801
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by Hedgehog R-HSA-5358351
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of RNA R-HSA-8953854
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Apoptosis R-HSA-109581
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by ROBO receptors R-HSA-376176
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic G1 phase and G1/S transition R-HSA-453279
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
HIV Infection R-HSA-162906
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent DNA Damage Response R-HSA-69610
RAF/MAP kinase cascade R-HSA-5673001
Post-translational protein modification R-HSA-597592
Orc1 removal from chromatin R-HSA-68949
Cell Cycle Checkpoints R-HSA-69620
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Separation of Sister Chromatids R-HSA-2467813
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of NF-kappaB in B cells R-HSA-1169091
S Phase R-HSA-69242
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Synthesis of DNA R-HSA-69239
Immune System R-HSA-168256
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
UCH proteinases R-HSA-5689603
Metabolism of polyamines R-HSA-351202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transport of small molecules R-HSA-382551
Metabolism R-HSA-1430728
ABC-family proteins mediated transport R-HSA-382556
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
G2/M Transition R-HSA-69275
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
FCERI mediated NF-kB activation R-HSA-2871837
Cellular response to hypoxia R-HSA-1234174
KEAP1-NFE2L2 pathway R-HSA-9755511
Deubiquitination R-HSA-5688426
Intracellular signaling by second messengers R-HSA-9006925
Signaling by NOTCH R-HSA-157118
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
PCP/CE pathway R-HSA-4086400
Signaling by Interleukins R-HSA-449147
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle, Mitotic R-HSA-69278
Asymmetric localization of PCP proteins R-HSA-4608870
Gene expression (Transcription) R-HSA-74160
Hedgehog 'off' state R-HSA-5610787
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
p53-Dependent G1 DNA Damage Response R-HSA-69563
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Class I MHC mediated antigen processing & presentation R-HSA-983169
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Generic Transcription Pathway R-HSA-212436
DNA Replication R-HSA-69306
Regulation of Apoptosis R-HSA-169911
Ub-specific processing proteases R-HSA-5689880
Mitotic Metaphase and Anaphase R-HSA-2555396
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of DVL R-HSA-4641258
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX1 R-HSA-8878171
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Developmental Biology R-HSA-1266738
Signaling by WNT R-HSA-195721
ABC transporter disorders R-HSA-5619084
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cell Cycle R-HSA-1640170
Regulation of RUNX2 expression and activity R-HSA-8939902
TCR signaling R-HSA-202403
Regulation of PTEN stability and activity R-HSA-8948751
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Beta-catenin independent WNT signaling R-HSA-3858494
ER-Phagosome pathway R-HSA-1236974
Cellular responses to stimuli R-HSA-8953897
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transcriptional regulation by RUNX2 R-HSA-8878166
Assembly of the pre-replicative complex R-HSA-68867
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of mitotic cell cycle R-HSA-453276
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G1/S DNA Damage Checkpoints R-HSA-69615
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic Anaphase R-HSA-68882
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of amino acids and derivatives R-HSA-71291
TCF dependent signaling in response to WNT R-HSA-201681
Infectious disease R-HSA-5663205
Downstream TCR signaling R-HSA-202424
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 signaling R-HSA-9020702
Neddylation R-HSA-8951664
Adaptive Immune System R-HSA-1280218
Cyclin E associated events during G1/S transition R-HSA-69202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
Interleukin-1 family signaling R-HSA-446652
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RAS by GAPs R-HSA-5658442
Mitotic G2-G2/M phases R-HSA-453274
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Post-translational protein modification R-HSA-597592
Apoptosis R-HSA-109581
PIP3 activates AKT signaling R-HSA-1257604
ER-Phagosome pathway R-HSA-1236974
Ub-specific processing proteases R-HSA-5689880
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Hedgehog R-HSA-5358351
Neddylation R-HSA-8951664
Signaling by NOTCH4 R-HSA-9013694
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX2 expression and activity R-HSA-8939902
Separation of Sister Chromatids R-HSA-2467813
Metabolism of proteins R-HSA-392499
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G2/M Checkpoints R-HSA-69481
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI2 by the proteasome R-HSA-5610783
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
Regulation of Apoptosis R-HSA-169911
Degradation of DVL R-HSA-4641258
Class I MHC mediated antigen processing & presentation R-HSA-983169
PCP/CE pathway R-HSA-4086400
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of GLI1 by the proteasome R-HSA-5610780
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Transition R-HSA-69275
Signal Transduction R-HSA-162582
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Generic Transcription Pathway R-HSA-212436
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stimuli R-HSA-8953897
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'off' state R-HSA-5610787
Hh mutants abrogate ligand secretion R-HSA-5387390
G1/S Transition R-HSA-69206
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism R-HSA-1430728
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle Checkpoints R-HSA-69620
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by WNT R-HSA-195721
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
TCR signaling R-HSA-202403
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 family signaling R-HSA-446652
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Metaphase and Anaphase R-HSA-2555396
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic G1 phase and G1/S transition R-HSA-453279
Antigen processing-Cross presentation R-HSA-1236975
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
KEAP1-NFE2L2 pathway R-HSA-9755511
ABC transporter disorders R-HSA-5619084
Regulation of RAS by GAPs R-HSA-5658442
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Axon guidance R-HSA-422475
Programmed Cell Death R-HSA-5357801
C-type lectin receptors (CLRs) R-HSA-5621481
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH R-HSA-157118
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Assembly of the pre-replicative complex R-HSA-68867
Nuclear events mediated by NFE2L2 R-HSA-9759194
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Downstream TCR signaling R-HSA-202424
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FCERI mediated NF-kB activation R-HSA-2871837
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of RUNX3 expression and activity R-HSA-8941858
Deubiquitination R-HSA-5688426
Regulation of PTEN stability and activity R-HSA-8948751
HIV Infection R-HSA-162906
Intracellular signaling by second messengers R-HSA-9006925
G1/S DNA Damage Checkpoints R-HSA-69615
Stabilization of p53 R-HSA-69541
Immune System R-HSA-168256
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular responses to stress R-HSA-2262752
Metabolism of amino acids and derivatives R-HSA-71291
Switching of origins to a post-replicative state R-HSA-69052
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Metabolism of polyamines R-HSA-351202
Hh mutants are degraded by ERAD R-HSA-5362768
UCH proteinases R-HSA-5689603
PTEN Regulation R-HSA-6807070
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of NOTCH4 signaling R-HSA-9604323
Developmental Biology R-HSA-1266738
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of AXIN R-HSA-4641257
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Interleukins R-HSA-449147
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Infectious disease R-HSA-5663205
Hedgehog 'on' state R-HSA-5632684
Disorders of transmembrane transporters R-HSA-5619115
Cellular response to chemical stress R-HSA-9711123
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle, Mitotic R-HSA-69278
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular response to hypoxia R-HSA-1234174
Synthesis of DNA R-HSA-69239
Transport of small molecules R-HSA-382551
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Innate Immune System R-HSA-168249
p53-Independent DNA Damage Response R-HSA-69610
Mitotic Anaphase R-HSA-68882
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Disease R-HSA-1643685
MAPK1/MAPK3 signaling R-HSA-5684996
Stabilization of p53 R-HSA-69541
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle Checkpoints R-HSA-69620
Post-translational protein modification R-HSA-597592
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cell Cycle R-HSA-1640170
S Phase R-HSA-69242
PCP/CE pathway R-HSA-4086400
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX3 R-HSA-8878159
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Interleukin-1 family signaling R-HSA-446652
Antigen processing-Cross presentation R-HSA-1236975
Regulation of Apoptosis R-HSA-169911
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Orc1 removal from chromatin R-HSA-68949
Hh mutants are degraded by ERAD R-HSA-5362768
Programmed Cell Death R-HSA-5357801
Infectious disease R-HSA-5663205
Apoptosis R-HSA-109581
Hedgehog 'on' state R-HSA-5632684
Signaling by NOTCH R-HSA-157118
Degradation of GLI2 by the proteasome R-HSA-5610783
Downstream TCR signaling R-HSA-202424
Regulation of expression of SLITs and ROBOs R-HSA-9010553
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by Interleukins R-HSA-449147
ER-Phagosome pathway R-HSA-1236974
Degradation of AXIN R-HSA-4641257
Metabolism of amino acids and derivatives R-HSA-71291
p53-Independent DNA Damage Response R-HSA-69610
Mitotic Anaphase R-HSA-68882
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of PTEN stability and activity R-HSA-8948751
RNA Polymerase II Transcription R-HSA-73857
G2/M Transition R-HSA-69275
PTEN Regulation R-HSA-6807070
Signaling by ROBO receptors R-HSA-376176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
TCF dependent signaling in response to WNT R-HSA-201681
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular responses to stimuli R-HSA-8953897
Beta-catenin independent WNT signaling R-HSA-3858494
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Immune System R-HSA-168256
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Interleukin-1 signaling R-HSA-9020702
Signaling by WNT R-HSA-195721
Degradation of DVL R-HSA-4641258
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
Host Interactions of HIV factors R-HSA-162909
Cellular response to chemical stress R-HSA-9711123
CLEC7A (Dectin-1) signaling R-HSA-5607764
Gene expression (Transcription) R-HSA-74160
Hedgehog 'off' state R-HSA-5610787
KEAP1-NFE2L2 pathway R-HSA-9755511
Generic Transcription Pathway R-HSA-212436
G1/S Transition R-HSA-69206
Nervous system development R-HSA-9675108
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX2 R-HSA-8878166
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cytokine Signaling in Immune system R-HSA-1280215
Deubiquitination R-HSA-5688426
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCERI mediated NF-kB activation R-HSA-2871837
TCR signaling R-HSA-202403
DNA Replication Pre-Initiation R-HSA-69002
Disorders of transmembrane transporters R-HSA-5619115
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of RNA R-HSA-8953854
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of proteins R-HSA-392499
C-type lectin receptors (CLRs) R-HSA-5621481
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle, Mitotic R-HSA-69278
Cellular response to hypoxia R-HSA-1234174
Signaling by Hedgehog R-HSA-5358351
Assembly of the pre-replicative complex R-HSA-68867
ABC-family proteins mediated transport R-HSA-382556
Innate Immune System R-HSA-168249
MAPK family signaling cascades R-HSA-5683057
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RAF/MAP kinase cascade R-HSA-5673001
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of polyamines R-HSA-351202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic G1 phase and G1/S transition R-HSA-453279
Neddylation R-HSA-8951664
PIP3 activates AKT signaling R-HSA-1257604
G1/S DNA Damage Checkpoints R-HSA-69615
UCH proteinases R-HSA-5689603
Switching of origins to a post-replicative state R-HSA-69052
MAPK6/MAPK4 signaling R-HSA-5687128
Transcriptional regulation by RUNX1 R-HSA-8878171
M Phase R-HSA-68886
Signaling by the B Cell Receptor (BCR) R-HSA-983705
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism R-HSA-1430728
Developmental Biology R-HSA-1266738
Regulation of RUNX2 expression and activity R-HSA-8939902
HIV Infection R-HSA-162906
Axon guidance R-HSA-422475
Mitotic G2-G2/M phases R-HSA-453274
Intracellular signaling by second messengers R-HSA-9006925
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Nuclear events mediated by NFE2L2 R-HSA-9759194
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transport of small molecules R-HSA-382551
DNA Replication R-HSA-69306
ABC transporter disorders R-HSA-5619084
Class I MHC mediated antigen processing & presentation R-HSA-983169
Synthesis of DNA R-HSA-69239
Regulation of RAS by GAPs R-HSA-5658442
G2/M Checkpoints R-HSA-69481
Cellular responses to stress R-HSA-2262752
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by NOTCH4 R-HSA-9013694

Expression Atlas ENSG00000100902
NCBI gene (formerly Entrezgene) 5687
GeneCards 9535
HGNC Symbol HGNC:9535
MIM gene 602855
MIM morbid 608446
UniProtKB Gene Name P60900
WikiGene 5687
Gene: PSMC5
Ensembl ID : ENSG00000087191
Description: proteasome 26S subunit, ATPase 5
Gene Synonyms: P45,P45/SUG,RPT6,S8,SUG-1,SUG1,TBP10,TRIP1
5 APIs:
219 Possible Orthologues:

G1/S Transition R-HSA-69206
G2/M Checkpoints R-HSA-69481
Hedgehog 'on' state R-HSA-5632684
S Phase R-HSA-69242
Degradation of DVL R-HSA-4641258
Signaling by NOTCH R-HSA-157118
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TCR signaling R-HSA-202403
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK family signaling cascades R-HSA-5683057
UCH proteinases R-HSA-5689603
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Deubiquitination R-HSA-5688426
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of amino acids and derivatives R-HSA-71291
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular responses to stimuli R-HSA-8953897
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
ABC-family proteins mediated transport R-HSA-382556
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle, Mitotic R-HSA-69278
Cytokine Signaling in Immune system R-HSA-1280215
Generic Transcription Pathway R-HSA-212436
Degradation of DVL R-HSA-4641258
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of Apoptosis R-HSA-169911
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK6/MAPK4 signaling R-HSA-5687128
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH4 R-HSA-9013694
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
Cell Cycle R-HSA-1640170
Programmed Cell Death R-HSA-5357801
Regulation of RAS by GAPs R-HSA-5658442
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog 'on' state R-HSA-5632684
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by ROBO receptors R-HSA-376176
Mitotic Anaphase R-HSA-68882
Regulation of RUNX3 expression and activity R-HSA-8941858
Negative regulation of NOTCH4 signaling R-HSA-9604323
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX2 expression and activity R-HSA-8939902
Beta-catenin independent WNT signaling R-HSA-3858494
Apoptosis R-HSA-109581
p53-Independent DNA Damage Response R-HSA-69610
Degradation of beta-catenin by the destruction complex R-HSA-195253
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
Cyclin E associated events during G1/S transition R-HSA-69202
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 signaling R-HSA-9020702
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by the B Cell Receptor (BCR) R-HSA-983705
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular response to chemical stress R-HSA-9711123
Orc1 removal from chromatin R-HSA-68949
Metabolism of RNA R-HSA-8953854
Transcriptional regulation by RUNX2 R-HSA-8878166
PIP3 activates AKT signaling R-HSA-1257604
Hh mutants are degraded by ERAD R-HSA-5362768
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ABC transporter disorders R-HSA-5619084
ER-Phagosome pathway R-HSA-1236974
MAPK1/MAPK3 signaling R-HSA-5684996
Host Interactions of HIV factors R-HSA-162909
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX1 R-HSA-8878171
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stress R-HSA-2262752
HIV Infection R-HSA-162906
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by NOTCH R-HSA-157118
Stabilization of p53 R-HSA-69541
Immune System R-HSA-168256
Metabolism of proteins R-HSA-392499
Developmental Biology R-HSA-1266738
Innate Immune System R-HSA-168249
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants abrogate ligand secretion R-HSA-5387390
S Phase R-HSA-69242
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle Checkpoints R-HSA-69620
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
PTEN Regulation R-HSA-6807070
Switching of origins to a post-replicative state R-HSA-69052
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Asymmetric localization of PCP proteins R-HSA-4608870
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication Pre-Initiation R-HSA-69002
Infectious disease R-HSA-5663205
PCP/CE pathway R-HSA-4086400
FCERI mediated NF-kB activation R-HSA-2871837
Activation of NF-kappaB in B cells R-HSA-1169091
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mitotic cell cycle R-HSA-453276
Signaling by WNT R-HSA-195721
Metabolism of polyamines R-HSA-351202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ub-specific processing proteases R-HSA-5689880
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by Interleukins R-HSA-449147
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Mitotic G2-G2/M phases R-HSA-453274
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog 'off' state R-HSA-5610787
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
Class I MHC mediated antigen processing & presentation R-HSA-983169
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Deubiquitination R-HSA-5688426
Programmed Cell Death R-HSA-5357801
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nuclear events mediated by NFE2L2 R-HSA-9759194
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Signaling by Interleukins R-HSA-449147
HIV Infection R-HSA-162906
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism R-HSA-1430728
Ub-specific processing proteases R-HSA-5689880
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'off' state R-HSA-5610787
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle R-HSA-1640170
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
Transport of small molecules R-HSA-382551
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin E associated events during G1/S transition R-HSA-69202
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream TCR signaling R-HSA-202424
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
TCR signaling R-HSA-202403
Synthesis of DNA R-HSA-69239
Signaling by NOTCH R-HSA-157118
Cellular responses to stress R-HSA-2262752
FCERI mediated NF-kB activation R-HSA-2871837
Beta-catenin independent WNT signaling R-HSA-3858494
Neddylation R-HSA-8951664
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Gene expression (Transcription) R-HSA-74160
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Post-translational protein modification R-HSA-597592
p53-Dependent G1 DNA Damage Response R-HSA-69563
PCP/CE pathway R-HSA-4086400
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
DNA Replication R-HSA-69306
G2/M Transition R-HSA-69275
Stabilization of p53 R-HSA-69541
Signaling by WNT R-HSA-195721
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing-Cross presentation R-HSA-1236975
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of AXIN R-HSA-4641257
Disorders of transmembrane transporters R-HSA-5619115
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
G2/M Checkpoints R-HSA-69481
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mitotic cell cycle R-HSA-453276
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of RNA R-HSA-8953854
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular response to hypoxia R-HSA-1234174
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'on' state R-HSA-5632684
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
ABC-family proteins mediated transport R-HSA-382556
Regulation of RAS by GAPs R-HSA-5658442
Immune System R-HSA-168256
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stimuli R-HSA-8953897
ER-Phagosome pathway R-HSA-1236974
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Class I MHC mediated antigen processing & presentation R-HSA-983169
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Mitotic Anaphase R-HSA-68882
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 family signaling R-HSA-446652
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Adaptive Immune System R-HSA-1280218
Vif-mediated degradation of APOBEC3G R-HSA-180585
Apoptosis R-HSA-109581
G1/S Transition R-HSA-69206
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by ROBO receptors R-HSA-376176
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of Apoptosis R-HSA-169911
Regulation of RUNX3 expression and activity R-HSA-8941858
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 signaling R-HSA-9020702
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of PTEN stability and activity R-HSA-8948751
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Generic Transcription Pathway R-HSA-212436
S Phase R-HSA-69242
Axon guidance R-HSA-422475
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Mitotic G2-G2/M phases R-HSA-453274
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic G1 phase and G1/S transition R-HSA-453279
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PIP3 activates AKT signaling R-HSA-1257604
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of DVL R-HSA-4641258
Nervous system development R-HSA-9675108
p53-Independent DNA Damage Response R-HSA-69610
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ABC-family proteins mediated transport R-HSA-382556
Infectious disease R-HSA-5663205
Metabolism R-HSA-1430728
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of RUNX3 expression and activity R-HSA-8941858
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Mitotic Metaphase and Anaphase R-HSA-2555396
ABC transporter disorders R-HSA-5619084
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Innate Immune System R-HSA-168249
G2/M Checkpoints R-HSA-69481
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RAS by GAPs R-HSA-5658442
RAF/MAP kinase cascade R-HSA-5673001
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by WNT R-HSA-195721
Stabilization of p53 R-HSA-69541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Activation of NF-kappaB in B cells R-HSA-1169091
Axon guidance R-HSA-422475
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hedgehog ligand biogenesis R-HSA-5358346
Cytokine Signaling in Immune system R-HSA-1280215
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX2 R-HSA-8878166
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RNA Polymerase II Transcription R-HSA-73857
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
CLEC7A (Dectin-1) signaling R-HSA-5607764
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream TCR signaling R-HSA-202424
Immune System R-HSA-168256
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MAPK family signaling cascades R-HSA-5683057
Nervous system development R-HSA-9675108
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Disorders of transmembrane transporters R-HSA-5619115
Regulation of mitotic cell cycle R-HSA-453276
Developmental Biology R-HSA-1266738
Hedgehog 'off' state R-HSA-5610787
Adaptive Immune System R-HSA-1280218
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PCP/CE pathway R-HSA-4086400
Assembly of the pre-replicative complex R-HSA-68867
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog 'on' state R-HSA-5632684
UCH proteinases R-HSA-5689603
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Independent DNA Damage Response R-HSA-69610
TCR signaling R-HSA-202403
Regulation of expression of SLITs and ROBOs R-HSA-9010553
C-type lectin receptors (CLRs) R-HSA-5621481
Generic Transcription Pathway R-HSA-212436
Deubiquitination R-HSA-5688426
Cellular responses to stress R-HSA-2262752
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX3 R-HSA-8878159
HIV Infection R-HSA-162906
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of polyamines R-HSA-351202
Cell Cycle Checkpoints R-HSA-69620
Defective CFTR causes cystic fibrosis R-HSA-5678895
Neddylation R-HSA-8951664
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of RNA R-HSA-8953854
Signaling by Hedgehog R-HSA-5358351
Separation of Sister Chromatids R-HSA-2467813
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S Transition R-HSA-69206
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Synthesis of DNA R-HSA-69239
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G2-G2/M phases R-HSA-453274
PTEN Regulation R-HSA-6807070
Regulation of Apoptosis R-HSA-169911
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of proteins R-HSA-392499
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication R-HSA-69306
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI2 by the proteasome R-HSA-5610783
Vif-mediated degradation of APOBEC3G R-HSA-180585
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stimuli R-HSA-8953897
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
Mitotic G1 phase and G1/S transition R-HSA-453279
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of amino acids and derivatives R-HSA-71291
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
S Phase R-HSA-69242
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Antigen processing-Cross presentation R-HSA-1236975
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI1 by the proteasome R-HSA-5610780
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to hypoxia R-HSA-1234174
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle, Mitotic R-HSA-69278
PIP3 activates AKT signaling R-HSA-1257604
Host Interactions of HIV factors R-HSA-162909
FCERI mediated NF-kB activation R-HSA-2871837
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX3 R-HSA-8878159
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of polyamines R-HSA-351202
Assembly of the pre-replicative complex R-HSA-68867
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
ER-Phagosome pathway R-HSA-1236974
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
Neddylation R-HSA-8951664
Degradation of AXIN R-HSA-4641257
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hedgehog 'on' state R-HSA-5632684
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
Synthesis of DNA R-HSA-69239
Degradation of DVL R-HSA-4641258
Hh mutants abrogate ligand secretion R-HSA-5387390
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
Signaling by NOTCH R-HSA-157118
Mitotic G2-G2/M phases R-HSA-453274
Metabolism R-HSA-1430728
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
Cell Cycle R-HSA-1640170
RAF/MAP kinase cascade R-HSA-5673001
Cellular response to hypoxia R-HSA-1234174
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by NOTCH4 R-HSA-9013694
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signal Transduction R-HSA-162582
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mitotic cell cycle R-HSA-453276
ABC transporter disorders R-HSA-5619084
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCR signaling R-HSA-202403
Regulation of Apoptosis R-HSA-169911
S Phase R-HSA-69242
Signaling by Interleukins R-HSA-449147
DNA Replication R-HSA-69306
Class I MHC mediated antigen processing & presentation R-HSA-983169
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
Cyclin E associated events during G1/S transition R-HSA-69202
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disease R-HSA-1643685
Signaling by Hedgehog R-HSA-5358351
Mitotic Metaphase and Anaphase R-HSA-2555396
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
HIV Infection R-HSA-162906
Degradation of GLI1 by the proteasome R-HSA-5610780
Programmed Cell Death R-HSA-5357801
Metabolism of RNA R-HSA-8953854
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transcriptional regulation by RUNX1 R-HSA-8878171
Post-translational protein modification R-HSA-597592
Regulation of RAS by GAPs R-HSA-5658442
Deubiquitination R-HSA-5688426
Adaptive Immune System R-HSA-1280218
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ub-specific processing proteases R-HSA-5689880
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
Signaling by ROBO receptors R-HSA-376176
Cell Cycle, Mitotic R-HSA-69278
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
M Phase R-HSA-68886
Hh mutants are degraded by ERAD R-HSA-5362768
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stimuli R-HSA-8953897
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by WNT R-HSA-195721
PCP/CE pathway R-HSA-4086400
PIP3 activates AKT signaling R-HSA-1257604
Cellular response to chemical stress R-HSA-9711123
Vpu mediated degradation of CD4 R-HSA-180534
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of PTEN stability and activity R-HSA-8948751
Stabilization of p53 R-HSA-69541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Transition R-HSA-69275
Regulation of expression of SLITs and ROBOs R-HSA-9010553
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of amino acids and derivatives R-HSA-71291
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Anaphase R-HSA-68882
Downstream TCR signaling R-HSA-202424
Host Interactions of HIV factors R-HSA-162909
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'off' state R-HSA-5610787
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing-Cross presentation R-HSA-1236975
FCERI mediated NF-kB activation R-HSA-2871837
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
KEAP1-NFE2L2 pathway R-HSA-9755511
Cytokine Signaling in Immune system R-HSA-1280215
Hedgehog ligand biogenesis R-HSA-5358346
C-type lectin receptors (CLRs) R-HSA-5621481
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Transport of small molecules R-HSA-382551
G1/S Transition R-HSA-69206
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX2 R-HSA-8878166
Interleukin-1 signaling R-HSA-9020702
Innate Immune System R-HSA-168249
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
PCP/CE pathway R-HSA-4086400
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
Mitotic G1 phase and G1/S transition R-HSA-453279
TCR signaling R-HSA-202403
p53-Dependent G1 DNA Damage Response R-HSA-69563
Axon guidance R-HSA-422475
ABC transporter disorders R-HSA-5619084
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Generic Transcription Pathway R-HSA-212436
Cell Cycle Checkpoints R-HSA-69620
PTEN Regulation R-HSA-6807070
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent DNA Damage Response R-HSA-69610
Asymmetric localization of PCP proteins R-HSA-4608870
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Stabilization of p53 R-HSA-69541
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'on' state R-HSA-5632684
Immune System R-HSA-168256
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of PTEN stability and activity R-HSA-8948751
RAF/MAP kinase cascade R-HSA-5673001
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of AXIN R-HSA-4641257
Metabolism of amino acids and derivatives R-HSA-71291
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vpu mediated degradation of CD4 R-HSA-180534
G1/S DNA Damage Checkpoints R-HSA-69615
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH R-HSA-157118
Signaling by the B Cell Receptor (BCR) R-HSA-983705
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mitotic cell cycle R-HSA-453276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Class I MHC mediated antigen processing & presentation R-HSA-983169
Programmed Cell Death R-HSA-5357801
Separation of Sister Chromatids R-HSA-2467813
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Nuclear events mediated by NFE2L2 R-HSA-9759194
Interleukin-1 signaling R-HSA-9020702
G2/M Checkpoints R-HSA-69481
Metabolism of proteins R-HSA-392499
Orc1 removal from chromatin R-HSA-68949
Defective CFTR causes cystic fibrosis R-HSA-5678895
HIV Infection R-HSA-162906
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Cyclin E associated events during G1/S transition R-HSA-69202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of Apoptosis R-HSA-169911
Adaptive Immune System R-HSA-1280218
Disorders of transmembrane transporters R-HSA-5619115
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by ROBO receptors R-HSA-376176
Metabolism of polyamines R-HSA-351202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Synthesis of DNA R-HSA-69239
Switching of origins to a post-replicative state R-HSA-69052
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
KEAP1-NFE2L2 pathway R-HSA-9755511
Ub-specific processing proteases R-HSA-5689880
Signaling by Interleukins R-HSA-449147
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Hedgehog ligand biogenesis R-HSA-5358346
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH4 R-HSA-9013694
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX3 R-HSA-8878159
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of RUNX3 expression and activity R-HSA-8941858
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing-Cross presentation R-HSA-1236975
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic G2-G2/M phases R-HSA-453274
ER-Phagosome pathway R-HSA-1236974
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Host Interactions of HIV factors R-HSA-162909
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
Cell Cycle R-HSA-1640170
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Cytokine Signaling in Immune system R-HSA-1280215
Vif-mediated degradation of APOBEC3G R-HSA-180585
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of RNA R-HSA-8953854
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S Transition R-HSA-69206
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
Interleukin-1 family signaling R-HSA-446652
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Anaphase R-HSA-68882
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX1 R-HSA-8878171
G2/M Checkpoints R-HSA-69481
Downstream TCR signaling R-HSA-202424
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants are degraded by ERAD R-HSA-5362768
Orc1 removal from chromatin R-HSA-68949
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Generic Transcription Pathway R-HSA-212436
S Phase R-HSA-69242
Ub-specific processing proteases R-HSA-5689880
Negative regulation of NOTCH4 signaling R-HSA-9604323
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FCERI mediated NF-kB activation R-HSA-2871837
Nuclear events mediated by NFE2L2 R-HSA-9759194
PCP/CE pathway R-HSA-4086400
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
UCH proteinases R-HSA-5689603
Cellular responses to stimuli R-HSA-8953897
Neddylation R-HSA-8951664
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Vpu mediated degradation of CD4 R-HSA-180534
Antigen processing-Cross presentation R-HSA-1236975
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of AXIN R-HSA-4641257
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RAS by GAPs R-HSA-5658442
Immune System R-HSA-168256
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signal Transduction R-HSA-162582
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of DVL R-HSA-4641258
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Intracellular signaling by second messengers R-HSA-9006925
HIV Infection R-HSA-162906
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
Disease R-HSA-1643685
Signaling by Interleukins R-HSA-449147
Metabolism of RNA R-HSA-8953854
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Synthesis of DNA R-HSA-69239
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Metaphase and Anaphase R-HSA-2555396
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCF dependent signaling in response to WNT R-HSA-201681
C-type lectin receptors (CLRs) R-HSA-5621481
ABC transporter disorders R-HSA-5619084
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH R-HSA-157118
Cyclin E associated events during G1/S transition R-HSA-69202
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Separation of Sister Chromatids R-HSA-2467813
Metabolism R-HSA-1430728
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by ROBO receptors R-HSA-376176
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Interleukin-1 signaling R-HSA-9020702
Mitotic Anaphase R-HSA-68882
ABC-family proteins mediated transport R-HSA-382556
Programmed Cell Death R-HSA-5357801
MAPK family signaling cascades R-HSA-5683057
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to chemical stress R-HSA-9711123
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by NOTCH4 R-HSA-9013694
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent DNA Damage Response R-HSA-69610
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stress R-HSA-2262752
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transport of small molecules R-HSA-382551
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Hedgehog R-HSA-5358351
Metabolism of amino acids and derivatives R-HSA-71291
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic G2-G2/M phases R-HSA-453274
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
Developmental Biology R-HSA-1266738
Regulation of RUNX2 expression and activity R-HSA-8939902
Adaptive Immune System R-HSA-1280218
Post-translational protein modification R-HSA-597592
Apoptosis R-HSA-109581
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog ligand biogenesis R-HSA-5358346
Gene expression (Transcription) R-HSA-74160
TCR signaling R-HSA-202403
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of NF-kappaB in B cells R-HSA-1169091
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 family signaling R-HSA-446652
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
HIV Infection R-HSA-162906
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of polyamines R-HSA-351202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Class I MHC mediated antigen processing & presentation R-HSA-983169
ABC-family proteins mediated transport R-HSA-382556
Metabolism R-HSA-1430728
PCP/CE pathway R-HSA-4086400
FCERI mediated NF-kB activation R-HSA-2871837
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Gene expression (Transcription) R-HSA-74160
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK6/MAPK4 signaling R-HSA-5687128
G2/M Transition R-HSA-69275
Transport of small molecules R-HSA-382551
Cell Cycle Checkpoints R-HSA-69620
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Ub-specific processing proteases R-HSA-5689880
Degradation of AXIN R-HSA-4641257
Developmental Biology R-HSA-1266738
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic G2-G2/M phases R-HSA-453274
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'on' state R-HSA-5632684
Degradation of DVL R-HSA-4641258
Cell Cycle R-HSA-1640170
Cellular responses to stimuli R-HSA-8953897
Post-translational protein modification R-HSA-597592
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
UCH proteinases R-HSA-5689603
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
Interleukin-1 signaling R-HSA-9020702
Signaling by Interleukins R-HSA-449147
Negative regulation of NOTCH4 signaling R-HSA-9604323
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
KEAP1-NFE2L2 pathway R-HSA-9755511
Neddylation R-HSA-8951664
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disorders of transmembrane transporters R-HSA-5619115
Synthesis of DNA R-HSA-69239
Regulation of PTEN stability and activity R-HSA-8948751
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Hh mutants are degraded by ERAD R-HSA-5362768
ABC transporter disorders R-HSA-5619084
Signaling by ROBO receptors R-HSA-376176
Axon guidance R-HSA-422475
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of mitotic cell cycle R-HSA-453276
TCR signaling R-HSA-202403
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Independent DNA Damage Response R-HSA-69610
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Deubiquitination R-HSA-5688426
Separation of Sister Chromatids R-HSA-2467813
M Phase R-HSA-68886
Hedgehog 'off' state R-HSA-5610787
PTEN Regulation R-HSA-6807070
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX3 R-HSA-8878159
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
RAF/MAP kinase cascade R-HSA-5673001
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of expression of SLITs and ROBOs R-HSA-9010553
C-type lectin receptors (CLRs) R-HSA-5621481
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
DNA Replication R-HSA-69306
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Anaphase R-HSA-68882
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to hypoxia R-HSA-1234174
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
Downstream TCR signaling R-HSA-202424
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX2 R-HSA-8878166
Antigen processing-Cross presentation R-HSA-1236975
Cellular response to chemical stress R-HSA-9711123
Nervous system development R-HSA-9675108
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by WNT R-HSA-195721
Regulation of RUNX3 expression and activity R-HSA-8941858
Immune System R-HSA-168256
G1/S Transition R-HSA-69206
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
MAPK family signaling cascades R-HSA-5683057
DNA Replication Pre-Initiation R-HSA-69002
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH4 R-HSA-9013694
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
Assembly of the pre-replicative complex R-HSA-68867
G2/M Checkpoints R-HSA-69481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
Beta-catenin independent WNT signaling R-HSA-3858494
Nuclear events mediated by NFE2L2 R-HSA-9759194
Programmed Cell Death R-HSA-5357801
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G1 phase and G1/S transition R-HSA-453279
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
Hedgehog 'off' state R-HSA-5610787
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Infectious disease R-HSA-5663205
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of beta-catenin by the destruction complex R-HSA-195253
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
p53-Independent DNA Damage Response R-HSA-69610
G2/M Checkpoints R-HSA-69481
Regulation of Apoptosis R-HSA-169911
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Transition R-HSA-69275
FCERI mediated NF-kB activation R-HSA-2871837
Asymmetric localization of PCP proteins R-HSA-4608870
UCH proteinases R-HSA-5689603
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Gene expression (Transcription) R-HSA-74160
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hh mutants abrogate ligand secretion R-HSA-5387390
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH R-HSA-157118
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Innate Immune System R-HSA-168249
Defective CFTR causes cystic fibrosis R-HSA-5678895
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog ligand biogenesis R-HSA-5358346
Adaptive Immune System R-HSA-1280218
Signaling by the B Cell Receptor (BCR) R-HSA-983705
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism R-HSA-1430728
PTEN Regulation R-HSA-6807070
MAPK family signaling cascades R-HSA-5683057
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of RNA R-HSA-8953854
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX3 R-HSA-8878159
Axon guidance R-HSA-422475
Assembly of the pre-replicative complex R-HSA-68867
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Apoptosis R-HSA-109581
Signaling by WNT R-HSA-195721
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of PTEN stability and activity R-HSA-8948751
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
TCF dependent signaling in response to WNT R-HSA-201681
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Class I MHC mediated antigen processing & presentation R-HSA-983169
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stress R-HSA-2262752
TCR signaling R-HSA-202403
DNA Replication R-HSA-69306
Cellular response to hypoxia R-HSA-1234174
Metabolism of proteins R-HSA-392499
HIV Infection R-HSA-162906
Signaling by Hedgehog R-HSA-5358351
Cell Cycle Checkpoints R-HSA-69620
Vif-mediated degradation of APOBEC3G R-HSA-180585
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Switching of origins to a post-replicative state R-HSA-69052
S Phase R-HSA-69242
Programmed Cell Death R-HSA-5357801
Mitotic G2-G2/M phases R-HSA-453274
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 family signaling R-HSA-446652
Degradation of AXIN R-HSA-4641257
RNA Polymerase II Transcription R-HSA-73857
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Transport of small molecules R-HSA-382551
Signaling by Interleukins R-HSA-449147
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of amino acids and derivatives R-HSA-71291
ABC transporter disorders R-HSA-5619084
PCP/CE pathway R-HSA-4086400
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Synthesis of DNA R-HSA-69239
Intracellular signaling by second messengers R-HSA-9006925
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Developmental Biology R-HSA-1266738
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of RAS by GAPs R-HSA-5658442
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
ABC-family proteins mediated transport R-HSA-382556
DNA Replication Pre-Initiation R-HSA-69002
Disease R-HSA-1643685
Separation of Sister Chromatids R-HSA-2467813
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants are degraded by ERAD R-HSA-5362768
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic Anaphase R-HSA-68882
G1/S Transition R-HSA-69206
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Nervous system development R-HSA-9675108
Cell Cycle, Mitotic R-HSA-69278
ER-Phagosome pathway R-HSA-1236974
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Immune System R-HSA-168256
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism of polyamines R-HSA-351202
PTEN Regulation R-HSA-6807070
Metabolism R-HSA-1430728
Infectious disease R-HSA-5663205
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
Signaling by ROBO receptors R-HSA-376176
Immune System R-HSA-168256
Assembly of the pre-replicative complex R-HSA-68867
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to hypoxia R-HSA-1234174
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of AXIN R-HSA-4641257
Apoptosis R-HSA-109581
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Axon guidance R-HSA-422475
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Interleukin-1 signaling R-HSA-9020702
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transcriptional regulation by RUNX2 R-HSA-8878166
Deubiquitination R-HSA-5688426
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ABC transporter disorders R-HSA-5619084
Signal Transduction R-HSA-162582
Cellular response to chemical stress R-HSA-9711123
Switching of origins to a post-replicative state R-HSA-69052
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
S Phase R-HSA-69242
Degradation of GLI2 by the proteasome R-HSA-5610783
G2/M Transition R-HSA-69275
Metabolism of RNA R-HSA-8953854
Synthesis of DNA R-HSA-69239
Hedgehog 'on' state R-HSA-5632684
DNA Replication R-HSA-69306
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Interleukins R-HSA-449147
Cellular responses to stress R-HSA-2262752
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
ABC-family proteins mediated transport R-HSA-382556
Metabolism of proteins R-HSA-392499
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CLEC7A (Dectin-1) signaling R-HSA-5607764
Orc1 removal from chromatin R-HSA-68949
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Beta-catenin independent WNT signaling R-HSA-3858494
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Transport of small molecules R-HSA-382551
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Hedgehog R-HSA-5358351
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
HIV Infection R-HSA-162906
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G1/S Transition R-HSA-69206
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle R-HSA-1640170
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog 'off' state R-HSA-5610787
ER-Phagosome pathway R-HSA-1236974
Separation of Sister Chromatids R-HSA-2467813
Mitotic G1 phase and G1/S transition R-HSA-453279
TCR signaling R-HSA-202403
G2/M Checkpoints R-HSA-69481
M Phase R-HSA-68886
Neddylation R-HSA-8951664
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hh mutants abrogate ligand secretion R-HSA-5387390
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of polyamines R-HSA-351202
Defective CFTR causes cystic fibrosis R-HSA-5678895
PCP/CE pathway R-HSA-4086400
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Adaptive Immune System R-HSA-1280218
Activation of NF-kappaB in B cells R-HSA-1169091
DNA Replication Pre-Initiation R-HSA-69002
p53-Dependent G1 DNA Damage Response R-HSA-69563
UCH proteinases R-HSA-5689603
p53-Independent DNA Damage Response R-HSA-69610
Generic Transcription Pathway R-HSA-212436
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of DVL R-HSA-4641258
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Innate Immune System R-HSA-168249
Regulation of mitotic cell cycle R-HSA-453276
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stimuli R-HSA-8953897
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by NOTCH R-HSA-157118
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Asymmetric localization of PCP proteins R-HSA-4608870
Programmed Cell Death R-HSA-5357801
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
Hedgehog ligand biogenesis R-HSA-5358346
ER-Phagosome pathway R-HSA-1236974
Signal Transduction R-HSA-162582
Signaling by NOTCH4 R-HSA-9013694
Stabilization of p53 R-HSA-69541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
Cyclin E associated events during G1/S transition R-HSA-69202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Assembly of the pre-replicative complex R-HSA-68867
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI2 by the proteasome R-HSA-5610783
C-type lectin receptors (CLRs) R-HSA-5621481
Intracellular signaling by second messengers R-HSA-9006925
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by Interleukins R-HSA-449147
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Independent DNA Damage Response R-HSA-69610
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic Metaphase and Anaphase R-HSA-2555396
FCERI mediated NF-kB activation R-HSA-2871837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism R-HSA-1430728
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of NF-kappaB in B cells R-HSA-1169091
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Synthesis of DNA R-HSA-69239
Metabolism of amino acids and derivatives R-HSA-71291
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by Hedgehog R-HSA-5358351
Gene expression (Transcription) R-HSA-74160
Regulation of mitotic cell cycle R-HSA-453276
Nuclear events mediated by NFE2L2 R-HSA-9759194
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'off' state R-HSA-5610787
Metabolism of RNA R-HSA-8953854
KEAP1-NFE2L2 pathway R-HSA-9755511
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
Cellular response to chemical stress R-HSA-9711123
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Innate Immune System R-HSA-168249
Transport of small molecules R-HSA-382551
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
PCP/CE pathway R-HSA-4086400
Regulation of expression of SLITs and ROBOs R-HSA-9010553
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cell Cycle Checkpoints R-HSA-69620
Degradation of AXIN R-HSA-4641257
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
Downstream TCR signaling R-HSA-202424
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication Pre-Initiation R-HSA-69002
Beta-catenin independent WNT signaling R-HSA-3858494
MAPK6/MAPK4 signaling R-HSA-5687128
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ABC transporter disorders R-HSA-5619084
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disorders of transmembrane transporters R-HSA-5619115
Immune System R-HSA-168256
Apoptosis R-HSA-109581
Regulation of Apoptosis R-HSA-169911
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Adaptive Immune System R-HSA-1280218
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX2 R-HSA-8878166
Orc1 removal from chromatin R-HSA-68949
Infectious disease R-HSA-5663205
ABC-family proteins mediated transport R-HSA-382556
DNA Replication R-HSA-69306
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCF dependent signaling in response to WNT R-HSA-201681
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
Interleukin-1 family signaling R-HSA-446652
G2/M Checkpoints R-HSA-69481
Cellular response to hypoxia R-HSA-1234174
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants abrogate ligand secretion R-HSA-5387390
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S Transition R-HSA-69206
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
UCH proteinases R-HSA-5689603
TCR signaling R-HSA-202403
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
Axon guidance R-HSA-422475
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by ROBO receptors R-HSA-376176
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Antigen processing-Cross presentation R-HSA-1236975
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog 'on' state R-HSA-5632684
HIV Infection R-HSA-162906
Deubiquitination R-HSA-5688426
Host Interactions of HIV factors R-HSA-162909
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
M Phase R-HSA-68886
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
Class I MHC mediated antigen processing & presentation R-HSA-983169
DNA Replication R-HSA-69306
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCF dependent signaling in response to WNT R-HSA-201681
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
S Phase R-HSA-69242
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Cyclin E associated events during G1/S transition R-HSA-69202
Intracellular signaling by second messengers R-HSA-9006925
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC-family proteins mediated transport R-HSA-382556
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Dependent G1 DNA Damage Response R-HSA-69563
Synthesis of DNA R-HSA-69239
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX3 R-HSA-8878159
Infectious disease R-HSA-5663205
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
ER-Phagosome pathway R-HSA-1236974
Immune System R-HSA-168256
Hedgehog 'on' state R-HSA-5632684
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cellular response to chemical stress R-HSA-9711123
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Neddylation R-HSA-8951664
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK family signaling cascades R-HSA-5683057
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G1 phase and G1/S transition R-HSA-453279
Deubiquitination R-HSA-5688426
Mitotic Anaphase R-HSA-68882
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Programmed Cell Death R-HSA-5357801
Hedgehog 'off' state R-HSA-5610787
Interleukin-1 family signaling R-HSA-446652
Developmental Biology R-HSA-1266738
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of proteins R-HSA-392499
Apoptosis R-HSA-109581
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants are degraded by ERAD R-HSA-5362768
Axon guidance R-HSA-422475
Disorders of transmembrane transporters R-HSA-5619115
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stress R-HSA-2262752
Disease R-HSA-1643685
Signaling by WNT R-HSA-195721
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
TCR signaling R-HSA-202403
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RAS by GAPs R-HSA-5658442
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of polyamines R-HSA-351202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to hypoxia R-HSA-1234174
G2/M Checkpoints R-HSA-69481
Ub-specific processing proteases R-HSA-5689880
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Hedgehog R-HSA-5358351
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of AXIN R-HSA-4641257
Mitotic G2-G2/M phases R-HSA-453274
Regulation of Apoptosis R-HSA-169911
p53-Independent DNA Damage Response R-HSA-69610
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism R-HSA-1430728
G1/S Transition R-HSA-69206
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle R-HSA-1640170
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
PTEN Regulation R-HSA-6807070
G2/M Transition R-HSA-69275
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
FCERI mediated NF-kB activation R-HSA-2871837
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Interleukin-1 signaling R-HSA-9020702
Antigen processing-Cross presentation R-HSA-1236975
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Orc1 removal from chromatin R-HSA-68949
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX2 expression and activity R-HSA-8939902
Post-translational protein modification R-HSA-597592
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of DVL R-HSA-4641258
Switching of origins to a post-replicative state R-HSA-69052
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH R-HSA-157118
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX1 R-HSA-8878171
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Innate Immune System R-HSA-168249
Cell Cycle Checkpoints R-HSA-69620
RAF/MAP kinase cascade R-HSA-5673001
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of PTEN stability and activity R-HSA-8948751
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000087191
NCBI gene (formerly Entrezgene) 5705
GeneCards 9552
HGNC Symbol HGNC:9552
MIM gene 601681
UniProtKB Gene Name P62195
WikiGene 5705