Gene: ELANE
Ensembl ID : ENSG00000197561
Description: elastase, neutrophil expressed
Gene Synonyms: ELA2,HLE,HNE,NE,PMN-E
2 APIs:
91 Possible Orthologues:

Neutrophil degranulation R-HSA-6798695
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Pyroptosis R-HSA-5620971
Immune System R-HSA-168256
Activation of Matrix Metalloproteinases R-HSA-1592389
Programmed Cell Death R-HSA-5357801
Collagen degradation R-HSA-1442490
Antimicrobial peptides R-HSA-6803157
Regulation of Complement cascade R-HSA-977606
Extracellular matrix organization R-HSA-1474244
Complement cascade R-HSA-166658
Regulated Necrosis R-HSA-5218859
Neutrophil degranulation R-HSA-6798695
Antimicrobial peptides R-HSA-6803157
Immune System R-HSA-168256
Programmed Cell Death R-HSA-5357801
Complement cascade R-HSA-166658
Innate Immune System R-HSA-168249
Pyroptosis R-HSA-5620971
Regulated Necrosis R-HSA-5218859
Degradation of the extracellular matrix R-HSA-1474228
Regulation of Complement cascade R-HSA-977606
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Collagen degradation R-HSA-1442490
Innate Immune System R-HSA-168249
Antimicrobial peptides R-HSA-6803157
Regulated Necrosis R-HSA-5218859
Collagen degradation R-HSA-1442490
Neutrophil degranulation R-HSA-6798695
Complement cascade R-HSA-166658
Regulation of Complement cascade R-HSA-977606
Degradation of the extracellular matrix R-HSA-1474228
Pyroptosis R-HSA-5620971
Programmed Cell Death R-HSA-5357801
Immune System R-HSA-168256
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Collagen degradation R-HSA-1442490
Regulation of Complement cascade R-HSA-977606
Pyroptosis R-HSA-5620971
Innate Immune System R-HSA-168249
Antimicrobial peptides R-HSA-6803157
Regulated Necrosis R-HSA-5218859
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Complement cascade R-HSA-166658
Programmed Cell Death R-HSA-5357801
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Complement cascade R-HSA-166658
Programmed Cell Death R-HSA-5357801
Antimicrobial peptides R-HSA-6803157
Innate Immune System R-HSA-168249
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Regulated Necrosis R-HSA-5218859
Immune System R-HSA-168256
Pyroptosis R-HSA-5620971
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Regulation of Complement cascade R-HSA-977606
Neutrophil degranulation R-HSA-6798695
Activation of Matrix Metalloproteinases R-HSA-1592389
Programmed Cell Death R-HSA-5357801
Extracellular matrix organization R-HSA-1474244
Regulation of Complement cascade R-HSA-977606
Immune System R-HSA-168256
Regulated Necrosis R-HSA-5218859
Collagen degradation R-HSA-1442490
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Antimicrobial peptides R-HSA-6803157
Pyroptosis R-HSA-5620971
Complement cascade R-HSA-166658
Pyroptosis R-HSA-5620971
Regulated Necrosis R-HSA-5218859
Programmed Cell Death R-HSA-5357801
Complement cascade R-HSA-166658
Regulation of Complement cascade R-HSA-977606
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Antimicrobial peptides R-HSA-6803157
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Extracellular matrix organization R-HSA-1474244
Neutrophil degranulation R-HSA-6798695
Regulated Necrosis R-HSA-5218859
Collagen degradation R-HSA-1442490
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Activation of Matrix Metalloproteinases R-HSA-1592389
Regulation of Complement cascade R-HSA-977606
Programmed Cell Death R-HSA-5357801
Complement cascade R-HSA-166658
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Innate Immune System R-HSA-168249
Antimicrobial peptides R-HSA-6803157
Pyroptosis R-HSA-5620971
Immune System R-HSA-168256
Complement cascade R-HSA-166658
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Regulation of Complement cascade R-HSA-977606
Activation of Matrix Metalloproteinases R-HSA-1592389
Neutrophil degranulation R-HSA-6798695
Antimicrobial peptides R-HSA-6803157
Innate Immune System R-HSA-168249
Regulated Necrosis R-HSA-5218859
Extracellular matrix organization R-HSA-1474244
Pyroptosis R-HSA-5620971
Programmed Cell Death R-HSA-5357801

Expression Atlas ENSG00000197561
LRG display in Ensembl gene LRG_57
NCBI gene (formerly Entrezgene) 1991
GeneCards 3309
HGNC Symbol HGNC:3309
MIM gene 130130
MIM morbid 202700
UniProtKB Gene Name P08246
WikiGene 1991
Gene: C1S
Ensembl ID : ENSG00000182326
Description: complement C1s
Gene Synonyms:
2 APIs:
199 Possible Orthologues:

Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Complement cascade R-HSA-166658
Classical antibody-mediated complement activation R-HSA-173623
Initial triggering of complement R-HSA-166663
Creation of C4 and C2 activators R-HSA-166786
Regulation of Complement cascade R-HSA-977606
Initial triggering of complement R-HSA-166663
Classical antibody-mediated complement activation R-HSA-173623
Regulation of Complement cascade R-HSA-977606
Complement cascade R-HSA-166658
Creation of C4 and C2 activators R-HSA-166786
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Classical antibody-mediated complement activation R-HSA-173623
Initial triggering of complement R-HSA-166663
Regulation of Complement cascade R-HSA-977606
Innate Immune System R-HSA-168249
Creation of C4 and C2 activators R-HSA-166786
Immune System R-HSA-168256
Complement cascade R-HSA-166658
Classical antibody-mediated complement activation R-HSA-173623
Creation of C4 and C2 activators R-HSA-166786
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Regulation of Complement cascade R-HSA-977606
Initial triggering of complement R-HSA-166663
Complement cascade R-HSA-166658
Classical antibody-mediated complement activation R-HSA-173623
Creation of C4 and C2 activators R-HSA-166786
Regulation of Complement cascade R-HSA-977606
Complement cascade R-HSA-166658
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Initial triggering of complement R-HSA-166663
Creation of C4 and C2 activators R-HSA-166786
Initial triggering of complement R-HSA-166663
Classical antibody-mediated complement activation R-HSA-173623
Complement cascade R-HSA-166658
Regulation of Complement cascade R-HSA-977606
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Initial triggering of complement R-HSA-166663
Regulation of Complement cascade R-HSA-977606
Classical antibody-mediated complement activation R-HSA-173623
Complement cascade R-HSA-166658
Creation of C4 and C2 activators R-HSA-166786
Initial triggering of complement R-HSA-166663
Complement cascade R-HSA-166658
Immune System R-HSA-168256
Regulation of Complement cascade R-HSA-977606
Creation of C4 and C2 activators R-HSA-166786
Innate Immune System R-HSA-168249
Classical antibody-mediated complement activation R-HSA-173623
Regulation of Complement cascade R-HSA-977606
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Complement cascade R-HSA-166658
Classical antibody-mediated complement activation R-HSA-173623
Initial triggering of complement R-HSA-166663
Creation of C4 and C2 activators R-HSA-166786
Immune System R-HSA-168256
Initial triggering of complement R-HSA-166663
Regulation of Complement cascade R-HSA-977606
Innate Immune System R-HSA-168249
Complement cascade R-HSA-166658
Creation of C4 and C2 activators R-HSA-166786
Classical antibody-mediated complement activation R-HSA-173623

Expression Atlas ENSG00000182326
LRG display in Ensembl gene LRG_25
NCBI gene (formerly Entrezgene) 716
GeneCards 1247
HGNC Symbol HGNC:1247
MIM gene 120580
MIM morbid 617174
UniProtKB Gene Name P09871
WikiGene 716
Gene Symbol : -
Ensembl ID : ENSG00000241253
Description: -
APIs:
Possible Orthologues:

Gene: F7
Ensembl ID : ENSG00000057593
Description: coagulation factor VII
Gene Synonyms:
1 APIs:
203 Possible Orthologues:

Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Hemostasis R-HSA-109582
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Circadian Clock R-HSA-400253
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Gamma-carboxylation of protein precursors R-HSA-159740
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Circadian Clock R-HSA-400253
Hemostasis R-HSA-109582
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Metabolism of proteins R-HSA-392499
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Post-translational protein modification R-HSA-597592
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Circadian Clock R-HSA-400253
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Post-translational protein modification R-HSA-597592
Hemostasis R-HSA-109582
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Metabolism of proteins R-HSA-392499
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Hemostasis R-HSA-109582
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Post-translational protein modification R-HSA-597592
Circadian Clock R-HSA-400253
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Metabolism of proteins R-HSA-392499
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Post-translational protein modification R-HSA-597592
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Gamma-carboxylation of protein precursors R-HSA-159740
Circadian Clock R-HSA-400253
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Hemostasis R-HSA-109582
Metabolism of proteins R-HSA-392499
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Post-translational protein modification R-HSA-597592
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Hemostasis R-HSA-109582
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Circadian Clock R-HSA-400253
Gamma-carboxylation of protein precursors R-HSA-159740
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Metabolism of proteins R-HSA-392499
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Metabolism of proteins R-HSA-392499
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Post-translational protein modification R-HSA-597592
Circadian Clock R-HSA-400253
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Hemostasis R-HSA-109582
Gamma-carboxylation of protein precursors R-HSA-159740
Hemostasis R-HSA-109582
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Circadian Clock R-HSA-400253
Gamma-carboxylation of protein precursors R-HSA-159740
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Circadian Clock R-HSA-400253
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Hemostasis R-HSA-109582
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877

Expression Atlas ENSG00000057593
LRG display in Ensembl gene LRG_554
NCBI gene (formerly Entrezgene) 2155
GeneCards 3544
HGNC Symbol HGNC:3544
MIM gene 613878
MIM morbid 608446
UniProtKB Gene Name P08709
WikiGene 2155
Gene: F10
Ensembl ID : ENSG00000126218
Description: coagulation factor X
Gene Synonyms:
10 APIs:
239 Possible Orthologues:

Hemostasis R-HSA-109582
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defective factor IX causes hemophilia B R-HSA-9668250
Defective factor IX causes thrombophilia R-HSA-9672383
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Defective F9 variant does not activate FX R-HSA-9673202
Common Pathway of Fibrin Clot Formation R-HSA-140875
Defective cofactor function of FVIIIa variant R-HSA-9672396
Metabolism of proteins R-HSA-392499
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Disease R-HSA-1643685
Post-translational protein modification R-HSA-597592
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Gamma-carboxylation of protein precursors R-HSA-159740
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor VIII causes hemophilia A R-HSA-9662001
Diseases of hemostasis R-HSA-9671793
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Disease R-HSA-1643685
Defective factor IX causes hemophilia B R-HSA-9668250
Defective factor IX causes thrombophilia R-HSA-9672383
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Defective factor VIII causes hemophilia A R-HSA-9662001
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Defective cofactor function of FVIIIa variant R-HSA-9672396
Gamma-carboxylation of protein precursors R-HSA-159740
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Defective F9 variant does not activate FX R-HSA-9673202
Common Pathway of Fibrin Clot Formation R-HSA-140875
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Diseases of hemostasis R-HSA-9671793
Hemostasis R-HSA-109582
Hemostasis R-HSA-109582
Defective F9 variant does not activate FX R-HSA-9673202
Defective factor VIII causes hemophilia A R-HSA-9662001
Disease R-HSA-1643685
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Common Pathway of Fibrin Clot Formation R-HSA-140875
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Defective factor IX causes hemophilia B R-HSA-9668250
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor IX causes thrombophilia R-HSA-9672383
Diseases of hemostasis R-HSA-9671793
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Post-translational protein modification R-HSA-597592
Gamma-carboxylation of protein precursors R-HSA-159740
Metabolism of proteins R-HSA-392499
Defective cofactor function of FVIIIa variant R-HSA-9672396
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Defective factor IX causes thrombophilia R-HSA-9672383
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Common Pathway of Fibrin Clot Formation R-HSA-140875
Hemostasis R-HSA-109582
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor VIII causes hemophilia A R-HSA-9662001
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defective cofactor function of FVIIIa variant R-HSA-9672396
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Gamma-carboxylation of protein precursors R-HSA-159740
Disease R-HSA-1643685
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Diseases of hemostasis R-HSA-9671793
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective F9 variant does not activate FX R-HSA-9673202
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Defective factor IX causes hemophilia B R-HSA-9668250
Hemostasis R-HSA-109582
Diseases of hemostasis R-HSA-9671793
Defective factor IX causes thrombophilia R-HSA-9672383
Defective cofactor function of FVIIIa variant R-HSA-9672396
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Common Pathway of Fibrin Clot Formation R-HSA-140875
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Post-translational protein modification R-HSA-597592
Defective factor IX causes hemophilia B R-HSA-9668250
Disease R-HSA-1643685
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Defective F9 variant does not activate FX R-HSA-9673202
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Defective factor VIII causes hemophilia A R-HSA-9662001
Metabolism of proteins R-HSA-392499
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Post-translational protein modification R-HSA-597592
Disease R-HSA-1643685
Defective factor IX causes hemophilia B R-HSA-9668250
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Defective F9 variant does not activate FX R-HSA-9673202
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Defective cofactor function of FVIIIa variant R-HSA-9672396
Defective factor VIII causes hemophilia A R-HSA-9662001
Defective factor IX causes thrombophilia R-HSA-9672383
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Common Pathway of Fibrin Clot Formation R-HSA-140875
Diseases of hemostasis R-HSA-9671793
Metabolism of proteins R-HSA-392499
Hemostasis R-HSA-109582
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Gamma-carboxylation of protein precursors R-HSA-159740
Common Pathway of Fibrin Clot Formation R-HSA-140875
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective cofactor function of FVIIIa variant R-HSA-9672396
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Defective factor IX causes thrombophilia R-HSA-9672383
Defective F9 variant does not activate FX R-HSA-9673202
Metabolism of proteins R-HSA-392499
Diseases of hemostasis R-HSA-9671793
Hemostasis R-HSA-109582
Disease R-HSA-1643685
Defective factor IX causes hemophilia B R-HSA-9668250
Defective factor VIII causes hemophilia A R-HSA-9662001
Post-translational protein modification R-HSA-597592
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Gamma-carboxylation of protein precursors R-HSA-159740
Hemostasis R-HSA-109582
Defective factor IX causes thrombophilia R-HSA-9672383
Defective factor IX causes hemophilia B R-HSA-9668250
Defective factor VIII causes hemophilia A R-HSA-9662001
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Disease R-HSA-1643685
Post-translational protein modification R-HSA-597592
Common Pathway of Fibrin Clot Formation R-HSA-140875
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective cofactor function of FVIIIa variant R-HSA-9672396
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Diseases of hemostasis R-HSA-9671793
Metabolism of proteins R-HSA-392499
Defective F9 variant does not activate FX R-HSA-9673202
Diseases of hemostasis R-HSA-9671793
Defective factor IX causes hemophilia B R-HSA-9668250
Defective factor VIII causes hemophilia A R-HSA-9662001
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Hemostasis R-HSA-109582
Post-translational protein modification R-HSA-597592
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Common Pathway of Fibrin Clot Formation R-HSA-140875
Gamma-carboxylation of protein precursors R-HSA-159740
Metabolism of proteins R-HSA-392499
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective factor IX causes thrombophilia R-HSA-9672383
Disease R-HSA-1643685
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Defective F9 variant does not activate FX R-HSA-9673202
Defective cofactor function of FVIIIa variant R-HSA-9672396

Expression Atlas ENSG00000126218
LRG display in Ensembl gene LRG_548
NCBI gene (formerly Entrezgene) 2159
GeneCards 3528
HGNC Symbol HGNC:3528
MIM gene 613872
MIM morbid 227600
UniProtKB Gene Name Q5JVE8
WikiGene 2159
Gene: PLG
Ensembl ID : ENSG00000122194
Description: plasminogen
Gene Synonyms:
12 APIs:
263 Possible Orthologues:

Signaling by PDGF R-HSA-186797
Metabolism of proteins R-HSA-392499
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Platelet degranulation R-HSA-114608
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Hemostasis R-HSA-109582
Extracellular matrix organization R-HSA-1474244
Platelet activation, signaling and aggregation R-HSA-76002
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
Dissolution of Fibrin Clot R-HSA-75205
Degradation of the extracellular matrix R-HSA-1474228
Dissolution of Fibrin Clot R-HSA-75205
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of proteins R-HSA-392499
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Signaling by PDGF R-HSA-186797
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Extracellular matrix organization R-HSA-1474244
Platelet degranulation R-HSA-114608
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Degradation of the extracellular matrix R-HSA-1474228
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Platelet degranulation R-HSA-114608
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism of proteins R-HSA-392499
Signaling by PDGF R-HSA-186797
Hemostasis R-HSA-109582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Dissolution of Fibrin Clot R-HSA-75205
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Platelet degranulation R-HSA-114608
Signaling by PDGF R-HSA-186797
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism of proteins R-HSA-392499
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Activation of Matrix Metalloproteinases R-HSA-1592389
Dissolution of Fibrin Clot R-HSA-75205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Extracellular matrix organization R-HSA-1474244
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Activation of Matrix Metalloproteinases R-HSA-1592389
Platelet degranulation R-HSA-114608
Extracellular matrix organization R-HSA-1474244
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of proteins R-HSA-392499
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Dissolution of Fibrin Clot R-HSA-75205
Signal Transduction R-HSA-162582
Hemostasis R-HSA-109582
Degradation of the extracellular matrix R-HSA-1474228
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by PDGF R-HSA-186797
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGF R-HSA-186797
Activation of Matrix Metalloproteinases R-HSA-1592389
Hemostasis R-HSA-109582
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signal Transduction R-HSA-162582
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Dissolution of Fibrin Clot R-HSA-75205
Metabolism of proteins R-HSA-392499
Platelet degranulation R-HSA-114608
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Platelet activation, signaling and aggregation R-HSA-76002
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Extracellular matrix organization R-HSA-1474244
Signaling by PDGF R-HSA-186797
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Degradation of the extracellular matrix R-HSA-1474228
Hemostasis R-HSA-109582
Platelet degranulation R-HSA-114608
Metabolism of proteins R-HSA-392499
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
Dissolution of Fibrin Clot R-HSA-75205
Metabolism of proteins R-HSA-392499
Hemostasis R-HSA-109582
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Signaling by PDGF R-HSA-186797
Platelet activation, signaling and aggregation R-HSA-76002
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Dissolution of Fibrin Clot R-HSA-75205
Platelet degranulation R-HSA-114608
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Activation of Matrix Metalloproteinases R-HSA-1592389
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Degradation of the extracellular matrix R-HSA-1474228
Platelet degranulation R-HSA-114608
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Hemostasis R-HSA-109582
Signaling by PDGF R-HSA-186797
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Dissolution of Fibrin Clot R-HSA-75205
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Platelet activation, signaling and aggregation R-HSA-76002
Signal Transduction R-HSA-162582
Platelet degranulation R-HSA-114608
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGF R-HSA-186797
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Hemostasis R-HSA-109582
Dissolution of Fibrin Clot R-HSA-75205
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Metabolism of proteins R-HSA-392499

Expression Atlas ENSG00000122194
LRG display in Ensembl gene LRG_571
NCBI gene (formerly Entrezgene) 5340
GeneCards 9071
HGNC Symbol HGNC:9071
MIM gene 173350
MIM morbid 619360
UniProtKB Gene Name Q5TEH5
WikiGene 5340
Gene: CFD
Ensembl ID : ENSG00000197766
Description: complement factor D
Gene Synonyms: ADN,DF,PFD
2 APIs:
134 Possible Orthologues:

Platelet degranulation R-HSA-114608
Alternative complement activation R-HSA-173736
Immune System R-HSA-168256
Initial triggering of complement R-HSA-166663
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Neutrophil degranulation R-HSA-6798695
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Innate Immune System R-HSA-168249
Complement cascade R-HSA-166658
Platelet degranulation R-HSA-114608
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Hemostasis R-HSA-109582
Neutrophil degranulation R-HSA-6798695
Alternative complement activation R-HSA-173736
Platelet activation, signaling and aggregation R-HSA-76002
Immune System R-HSA-168256
Initial triggering of complement R-HSA-166663
Innate Immune System R-HSA-168249
Complement cascade R-HSA-166658
Initial triggering of complement R-HSA-166663
Complement cascade R-HSA-166658
Neutrophil degranulation R-HSA-6798695
Alternative complement activation R-HSA-173736
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Platelet degranulation R-HSA-114608
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Initial triggering of complement R-HSA-166663
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Complement cascade R-HSA-166658
Hemostasis R-HSA-109582
Innate Immune System R-HSA-168249
Platelet degranulation R-HSA-114608
Alternative complement activation R-HSA-173736
Neutrophil degranulation R-HSA-6798695
Platelet activation, signaling and aggregation R-HSA-76002
Immune System R-HSA-168256
Initial triggering of complement R-HSA-166663
Innate Immune System R-HSA-168249
Platelet activation, signaling and aggregation R-HSA-76002
Immune System R-HSA-168256
Platelet degranulation R-HSA-114608
Hemostasis R-HSA-109582
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Complement cascade R-HSA-166658
Neutrophil degranulation R-HSA-6798695
Alternative complement activation R-HSA-173736
Hemostasis R-HSA-109582
Initial triggering of complement R-HSA-166663
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Innate Immune System R-HSA-168249
Alternative complement activation R-HSA-173736
Complement cascade R-HSA-166658
Immune System R-HSA-168256
Platelet degranulation R-HSA-114608
Platelet activation, signaling and aggregation R-HSA-76002
Neutrophil degranulation R-HSA-6798695
Hemostasis R-HSA-109582
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Initial triggering of complement R-HSA-166663
Alternative complement activation R-HSA-173736
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Complement cascade R-HSA-166658
Platelet degranulation R-HSA-114608
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Neutrophil degranulation R-HSA-6798695
Initial triggering of complement R-HSA-166663
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Alternative complement activation R-HSA-173736
Platelet degranulation R-HSA-114608
Immune System R-HSA-168256
Complement cascade R-HSA-166658
Platelet activation, signaling and aggregation R-HSA-76002
Innate Immune System R-HSA-168249
Innate Immune System R-HSA-168249
Platelet activation, signaling and aggregation R-HSA-76002
Platelet degranulation R-HSA-114608
Initial triggering of complement R-HSA-166663
Alternative complement activation R-HSA-173736
Immune System R-HSA-168256
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Complement cascade R-HSA-166658
Hemostasis R-HSA-109582
Neutrophil degranulation R-HSA-6798695

Expression Atlas ENSG00000197766
LRG display in Ensembl gene LRG_46
NCBI gene (formerly Entrezgene) 1675
GeneCards 2771
HGNC Symbol HGNC:2771
MIM gene 134350
MIM morbid 613912
UniProtKB Gene Name P00746
WikiGene 1675
Gene: CMA1
Ensembl ID : ENSG00000092009
Description: chymase 1
Gene Synonyms:
1 APIs:
317 Possible Orthologues:

Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Peptide hormone metabolism R-HSA-2980736
Signaling by SCF-KIT R-HSA-1433557
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Peptide hormone metabolism R-HSA-2980736
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Activation of Matrix Metalloproteinases R-HSA-1592389
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Signaling by SCF-KIT R-HSA-1433557
Peptide hormone metabolism R-HSA-2980736
Degradation of the extracellular matrix R-HSA-1474228
Signal Transduction R-HSA-162582
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Peptide hormone metabolism R-HSA-2980736
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of proteins R-HSA-392499
Extracellular matrix organization R-HSA-1474244
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Activation of Matrix Metalloproteinases R-HSA-1592389
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Peptide hormone metabolism R-HSA-2980736
Signal Transduction R-HSA-162582
Signaling by SCF-KIT R-HSA-1433557
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Extracellular matrix organization R-HSA-1474244
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Extracellular matrix organization R-HSA-1474244
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by SCF-KIT R-HSA-1433557
Signal Transduction R-HSA-162582
Activation of Matrix Metalloproteinases R-HSA-1592389
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of proteins R-HSA-392499
Extracellular matrix organization R-HSA-1474244
Peptide hormone metabolism R-HSA-2980736
Signal Transduction R-HSA-162582
Signaling by SCF-KIT R-HSA-1433557
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Degradation of the extracellular matrix R-HSA-1474228
Activation of Matrix Metalloproteinases R-HSA-1592389
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activation of Matrix Metalloproteinases R-HSA-1592389
Peptide hormone metabolism R-HSA-2980736
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by SCF-KIT R-HSA-1433557
Metabolism of proteins R-HSA-392499
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Extracellular matrix organization R-HSA-1474244
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of proteins R-HSA-392499
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Signaling by SCF-KIT R-HSA-1433557

Expression Atlas ENSG00000092009
NCBI gene (formerly Entrezgene) 1215
GeneCards 2097
HGNC Symbol HGNC:2097
MIM gene 118938
UniProtKB Gene Name P23946
WikiGene 1215