Gene: AURKA
Ensembl ID : ENSG00000087586
Description: aurora kinase A
Gene Synonyms: AIK,ARK1,AURA,BTAK,PPP1R47,STK15,STK6,STK7
10 APIs:
229 Possible Orthologues:

APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Mitotic G2-G2/M phases R-HSA-453274
Interaction between PHLDA1 and AURKA R-HSA-8854521
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Regulation of TP53 Activity R-HSA-5633007
Gene expression (Transcription) R-HSA-74160
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
AURKA Activation by TPX2 R-HSA-8854518
Post-translational protein modification R-HSA-597592
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of mitotic cell cycle R-HSA-453276
RNA Polymerase II Transcription R-HSA-73857
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Interaction between PHLDA1 and AURKA R-HSA-8854521
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Transcriptional Regulation by TP53 R-HSA-3700989
Cell Cycle, Mitotic R-HSA-69278
AURKA Activation by TPX2 R-HSA-8854518
Regulation of TP53 Activity R-HSA-5633007
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
Mitotic G2-G2/M phases R-HSA-453274
Gene expression (Transcription) R-HSA-74160
SUMOylation of DNA replication proteins R-HSA-4615885
Post-translational protein modification R-HSA-597592
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
G2/M Transition R-HSA-69275
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G2/M Transition R-HSA-69275
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Interaction between PHLDA1 and AURKA R-HSA-8854521
Generic Transcription Pathway R-HSA-212436
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Transcriptional Regulation by TP53 R-HSA-3700989
Post-translational protein modification R-HSA-597592
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Cell Cycle R-HSA-1640170
SUMOylation of DNA replication proteins R-HSA-4615885
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G2-G2/M phases R-HSA-453274
SUMOylation R-HSA-2990846
AURKA Activation by TPX2 R-HSA-8854518
RNA Polymerase II Transcription R-HSA-73857
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cell Cycle, Mitotic R-HSA-69278
Regulation of TP53 Activity R-HSA-5633007
Regulation of mitotic cell cycle R-HSA-453276
AURKA Activation by TPX2 R-HSA-8854518
Interaction between PHLDA1 and AURKA R-HSA-8854521
Cell Cycle R-HSA-1640170
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation of DNA replication proteins R-HSA-4615885
Post-translational protein modification R-HSA-597592
Regulation of TP53 Activity R-HSA-5633007
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Cell Cycle, Mitotic R-HSA-69278
Metabolism of proteins R-HSA-392499
G2/M Transition R-HSA-69275
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by TP53 R-HSA-3700989
SUMOylation R-HSA-2990846
Gene expression (Transcription) R-HSA-74160
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
RNA Polymerase II Transcription R-HSA-73857
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Regulation of TP53 Activity R-HSA-5633007
AURKA Activation by TPX2 R-HSA-8854518
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Post-translational protein modification R-HSA-597592
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of mitotic cell cycle R-HSA-453276
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Cell Cycle R-HSA-1640170
Metabolism of proteins R-HSA-392499
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Mitotic G2-G2/M phases R-HSA-453274
G2/M Transition R-HSA-69275
Gene expression (Transcription) R-HSA-74160
Cell Cycle, Mitotic R-HSA-69278
SUMOylation R-HSA-2990846
Interaction between PHLDA1 and AURKA R-HSA-8854521
Transcriptional Regulation by TP53 R-HSA-3700989
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Metabolism of proteins R-HSA-392499
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Interaction between PHLDA1 and AURKA R-HSA-8854521
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Post-translational protein modification R-HSA-597592
SUMOylation of DNA replication proteins R-HSA-4615885
AURKA Activation by TPX2 R-HSA-8854518
Regulation of mitotic cell cycle R-HSA-453276
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SUMOylation R-HSA-2990846
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity R-HSA-5633007
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Mitotic G2-G2/M phases R-HSA-453274
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
AURKA Activation by TPX2 R-HSA-8854518
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Generic Transcription Pathway R-HSA-212436
Cell Cycle, Mitotic R-HSA-69278
Mitotic G2-G2/M phases R-HSA-453274
SUMOylation R-HSA-2990846
Transcriptional Regulation by TP53 R-HSA-3700989
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of TP53 Activity R-HSA-5633007
Metabolism of proteins R-HSA-392499
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Regulation of mitotic cell cycle R-HSA-453276
Interaction between PHLDA1 and AURKA R-HSA-8854521
G2/M Transition R-HSA-69275
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Metabolism of proteins R-HSA-392499
Interaction between PHLDA1 and AURKA R-HSA-8854521
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Post-translational protein modification R-HSA-597592
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of TP53 Activity R-HSA-5633007
G2/M Transition R-HSA-69275
Regulation of mitotic cell cycle R-HSA-453276
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AURKA Activation by TPX2 R-HSA-8854518
Transcriptional Regulation by TP53 R-HSA-3700989
Gene expression (Transcription) R-HSA-74160
SUMOylation R-HSA-2990846
Mitotic G2-G2/M phases R-HSA-453274
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
AURKA Activation by TPX2 R-HSA-8854518
RNA Polymerase II Transcription R-HSA-73857
Regulation of mitotic cell cycle R-HSA-453276
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G2/M Transition R-HSA-69275
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
SUMOylation R-HSA-2990846
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of TP53 Activity R-HSA-5633007
Interaction between PHLDA1 and AURKA R-HSA-8854521
Post-translational protein modification R-HSA-597592
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cell Cycle, Mitotic R-HSA-69278
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by TP53 R-HSA-3700989
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Cell Cycle R-HSA-1640170
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G2/M Transition R-HSA-69275
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of TP53 Activity R-HSA-5633007
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
RNA Polymerase II Transcription R-HSA-73857
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
AURKA Activation by TPX2 R-HSA-8854518
Interaction between PHLDA1 and AURKA R-HSA-8854521
SUMOylation R-HSA-2990846
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Metabolism of proteins R-HSA-392499
Regulation of mitotic cell cycle R-HSA-453276
Post-translational protein modification R-HSA-597592
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cell Cycle R-HSA-1640170
Post-translational protein modification R-HSA-597592
Gene expression (Transcription) R-HSA-74160
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of TP53 Activity R-HSA-5633007
Interaction between PHLDA1 and AURKA R-HSA-8854521
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic G2-G2/M phases R-HSA-453274
RNA Polymerase II Transcription R-HSA-73857
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle, Mitotic R-HSA-69278
Transcriptional Regulation by TP53 R-HSA-3700989
Metabolism of proteins R-HSA-392499
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
G2/M Transition R-HSA-69275
Generic Transcription Pathway R-HSA-212436
SUMOylation R-HSA-2990846
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
AURKA Activation by TPX2 R-HSA-8854518

Expression Atlas ENSG00000087586
NCBI gene (formerly Entrezgene) 6790
GeneCards 11393
HGNC Symbol HGNC:11393
MIM gene 603072
MIM morbid 114500
UniProtKB Gene Name Q5QPD4
WikiGene 6790
Gene: PRKCZ
Ensembl ID : ENSG00000067606
Description: protein kinase C zeta
Gene Synonyms: PKC2
5 APIs:
201 Possible Orthologues:

Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
GPVI-mediated activation cascade R-HSA-114604
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
RHO GTPase Effectors R-HSA-195258
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by TGFB family members R-HSA-9006936
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
ESR-mediated signaling R-HSA-8939211
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by VEGF R-HSA-194138
Hemostasis R-HSA-109582
Extra-nuclear estrogen signaling R-HSA-9009391
VEGFA-VEGFR2 Pathway R-HSA-4420097
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases R-HSA-194315
RHO GTPase Effectors R-HSA-195258
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by TGFB family members R-HSA-9006936
Signaling by Nuclear Receptors R-HSA-9006931
VEGFA-VEGFR2 Pathway R-HSA-4420097
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Rho GTPases R-HSA-194315
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Signaling by TGF-beta Receptor Complex R-HSA-170834
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
VEGFR2 mediated cell proliferation R-HSA-5218921
Signal Transduction R-HSA-162582
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by VEGF R-HSA-194138
ESR-mediated signaling R-HSA-8939211
GPVI-mediated activation cascade R-HSA-114604
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
ESR-mediated signaling R-HSA-8939211
Platelet activation, signaling and aggregation R-HSA-76002
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Rho GTPases R-HSA-194315
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by TGFB family members R-HSA-9006936
Hemostasis R-HSA-109582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by VEGF R-HSA-194138
RHO GTPase Effectors R-HSA-195258
GPVI-mediated activation cascade R-HSA-114604
Signal Transduction R-HSA-162582
Signaling by TGF-beta Receptor Complex R-HSA-170834
VEGFA-VEGFR2 Pathway R-HSA-4420097
VEGFR2 mediated cell proliferation R-HSA-5218921
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
VEGFR2 mediated cell proliferation R-HSA-5218921
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Hemostasis R-HSA-109582
RHO GTPase Effectors R-HSA-195258
Platelet activation, signaling and aggregation R-HSA-76002
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling by TGFB family members R-HSA-9006936
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Rho GTPases R-HSA-194315
Signaling by TGF-beta Receptor Complex R-HSA-170834
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Nuclear Receptors R-HSA-9006931
ESR-mediated signaling R-HSA-8939211
Signal Transduction R-HSA-162582
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
GPVI-mediated activation cascade R-HSA-114604
GPVI-mediated activation cascade R-HSA-114604
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by VEGF R-HSA-194138
Signaling by TGF-beta Receptor Complex R-HSA-170834
RHO GTPase Effectors R-HSA-195258
VEGFR2 mediated cell proliferation R-HSA-5218921
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Rho GTPases R-HSA-194315
ESR-mediated signaling R-HSA-8939211
Signaling by TGFB family members R-HSA-9006936
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Hemostasis R-HSA-109582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Rho GTPases R-HSA-194315
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
ESR-mediated signaling R-HSA-8939211
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by TGF-beta Receptor Complex R-HSA-170834
Hemostasis R-HSA-109582
GPVI-mediated activation cascade R-HSA-114604
VEGFA-VEGFR2 Pathway R-HSA-4420097
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
RHO GTPase Effectors R-HSA-195258
VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by VEGF R-HSA-194138
Signaling by Nuclear Receptors R-HSA-9006931
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by VEGF R-HSA-194138
Signaling by Nuclear Receptors R-HSA-9006931
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
VEGFR2 mediated cell proliferation R-HSA-5218921
RHO GTPase Effectors R-HSA-195258
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by TGFB family members R-HSA-9006936
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFA-VEGFR2 Pathway R-HSA-4420097
ESR-mediated signaling R-HSA-8939211
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
GPVI-mediated activation cascade R-HSA-114604
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Rho GTPases R-HSA-194315
Signaling by Rho GTPases R-HSA-194315
Extra-nuclear estrogen signaling R-HSA-9009391
VEGFA-VEGFR2 Pathway R-HSA-4420097
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Hemostasis R-HSA-109582
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by TGFB family members R-HSA-9006936
Signaling by TGF-beta Receptor Complex R-HSA-170834
RHO GTPase Effectors R-HSA-195258
GPVI-mediated activation cascade R-HSA-114604
VEGFR2 mediated cell proliferation R-HSA-5218921
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by VEGF R-HSA-194138
ESR-mediated signaling R-HSA-8939211
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002

Expression Atlas ENSG00000067606
NCBI gene (formerly Entrezgene) 5590
GeneCards 9412
HGNC Symbol HGNC:9412
MIM gene 176982
UniProtKB Gene Name Q05513
WikiGene 5590
Gene: CDK1
Ensembl ID : ENSG00000170312
Description: cyclin dependent kinase 1
Gene Synonyms: CDC2,CDC28A
9 APIs:
241 Possible Orthologues:

Mitotic Prophase R-HSA-68875
Gene expression (Transcription) R-HSA-74160
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
Mitotic G1 phase and G1/S transition R-HSA-453279
Deubiquitination R-HSA-5688426
G2/M Checkpoints R-HSA-69481
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Regulation of TP53 Degradation R-HSA-6804757
RNA Polymerase II Transcription R-HSA-73857
MAPK6/MAPK4 signaling R-HSA-5687128
Condensation of Prometaphase Chromosomes R-HSA-2514853
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Resolution of Sister Chromatid Cohesion R-HSA-2500257
E2F mediated regulation of DNA replication R-HSA-113510
Mitotic Prophase R-HSA-68875
Transcriptional Regulation by TP53 R-HSA-3700989
Ovarian tumor domain proteases R-HSA-5689896
G2/M Transition R-HSA-69275
Nuclear Envelope Breakdown R-HSA-2980766
G1/S-Specific Transcription R-HSA-69205
Phosphorylation of Emi1 R-HSA-176417
G2/M DNA replication checkpoint R-HSA-69478
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Anchoring of the basal body to the plasma membrane R-HSA-5620912
M Phase R-HSA-68886
Phosphorylation of the APC/C R-HSA-176412
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Cell Cycle, Mitotic R-HSA-69278
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Mitotic Prometaphase R-HSA-68877
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Gene expression (Transcription) R-HSA-74160
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
G1/S Transition R-HSA-69206
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Cilium Assembly R-HSA-5617833
Mitotic Anaphase R-HSA-68882
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
MAPK family signaling cascades R-HSA-5683057
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
MAPK3 (ERK1) activation R-HSA-110056
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle Checkpoints R-HSA-69620
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G2/M DNA damage checkpoint R-HSA-69473
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
MASTL Facilitates Mitotic Progression R-HSA-2465910
Centrosome maturation R-HSA-380287
Regulation of TP53 Activity R-HSA-5633007
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Condensation of Prophase Chromosomes R-HSA-2299718
RAF-independent MAPK1/3 activation R-HSA-112409
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Cell Cycle R-HSA-1640170
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
AURKA Activation by TPX2 R-HSA-8854518
Loss of Nlp from mitotic centrosomes R-HSA-380259
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G0 and Early G1 R-HSA-1538133
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic Metaphase and Anaphase R-HSA-2555396
Organelle biogenesis and maintenance R-HSA-1852241
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Regulation of mitotic cell cycle R-HSA-453276
MAPK3 (ERK1) activation R-HSA-110056
AURKA Activation by TPX2 R-HSA-8854518
G1/S Transition R-HSA-69206
Mitotic Anaphase R-HSA-68882
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Expression and Degradation R-HSA-6806003
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Loss of Nlp from mitotic centrosomes R-HSA-380259
Phosphorylation of Emi1 R-HSA-176417
Nuclear Envelope Breakdown R-HSA-2980766
G0 and Early G1 R-HSA-1538133
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
Mitotic Metaphase and Anaphase R-HSA-2555396
Ovarian tumor domain proteases R-HSA-5689896
Depolymerisation of the Nuclear Lamina R-HSA-4419969
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Mitotic G1 phase and G1/S transition R-HSA-453279
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
G2/M DNA replication checkpoint R-HSA-69478
Organelle biogenesis and maintenance R-HSA-1852241
Mitotic G2-G2/M phases R-HSA-453274
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
E2F mediated regulation of DNA replication R-HSA-113510
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
G2/M DNA damage checkpoint R-HSA-69473
MAPK1/MAPK3 signaling R-HSA-5684996
Generic Transcription Pathway R-HSA-212436
Mitotic Prophase R-HSA-68875
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Gene expression (Transcription) R-HSA-74160
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Phosphorylation of the APC/C R-HSA-176412
Regulation of TP53 Degradation R-HSA-6804757
Cilium Assembly R-HSA-5617833
Centrosome maturation R-HSA-380287
Deubiquitination R-HSA-5688426
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G2/M Checkpoints R-HSA-69481
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
M Phase R-HSA-68886
Transcriptional Regulation by TP53 R-HSA-3700989
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Cell Cycle R-HSA-1640170
Condensation of Prometaphase Chromosomes R-HSA-2514853
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Transcriptional regulation by RUNX2 R-HSA-8878166
MASTL Facilitates Mitotic Progression R-HSA-2465910
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Regulation of TP53 Activity R-HSA-5633007
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Cell Cycle Checkpoints R-HSA-69620
Metabolism of proteins R-HSA-392499
MAPK family signaling cascades R-HSA-5683057
Condensation of Prophase Chromosomes R-HSA-2299718
G1/S-Specific Transcription R-HSA-69205
RAF-independent MAPK1/3 activation R-HSA-112409
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mitotic cell cycle R-HSA-453276
Post-translational protein modification R-HSA-597592
Ovarian tumor domain proteases R-HSA-5689896
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nuclear Envelope Breakdown R-HSA-2980766
Condensation of Prometaphase Chromosomes R-HSA-2514853
Loss of Nlp from mitotic centrosomes R-HSA-380259
Deubiquitination R-HSA-5688426
AURKA Activation by TPX2 R-HSA-8854518
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Depolymerisation of the Nuclear Lamina R-HSA-4419969
RAF-independent MAPK1/3 activation R-HSA-112409
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of proteins R-HSA-392499
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Regulation of TP53 Expression and Degradation R-HSA-6806003
Mitotic Prometaphase R-HSA-68877
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
M Phase R-HSA-68886
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic Anaphase R-HSA-68882
G2/M Checkpoints R-HSA-69481
G0 and Early G1 R-HSA-1538133
G1/S Transition R-HSA-69206
Mitotic G2-G2/M phases R-HSA-453274
Anchoring of the basal body to the plasma membrane R-HSA-5620912
E2F mediated regulation of DNA replication R-HSA-113510
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Cell Cycle, Mitotic R-HSA-69278
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Degradation R-HSA-6804757
Transcriptional Regulation by TP53 R-HSA-3700989
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Mitotic Metaphase and Anaphase R-HSA-2555396
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
G2/M DNA damage checkpoint R-HSA-69473
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
MASTL Facilitates Mitotic Progression R-HSA-2465910
Signal Transduction R-HSA-162582
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Organelle biogenesis and maintenance R-HSA-1852241
G2/M DNA replication checkpoint R-HSA-69478
Phosphorylation of the APC/C R-HSA-176412
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Regulation of TP53 Activity R-HSA-5633007
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
Centrosome maturation R-HSA-380287
Phosphorylation of Emi1 R-HSA-176417
Condensation of Prophase Chromosomes R-HSA-2299718
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
MAPK3 (ERK1) activation R-HSA-110056
MAPK family signaling cascades R-HSA-5683057
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Cilium Assembly R-HSA-5617833
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S-Specific Transcription R-HSA-69205
G2/M Transition R-HSA-69275
Cell Cycle Checkpoints R-HSA-69620
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of mitotic cell cycle R-HSA-453276
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
MAPK3 (ERK1) activation R-HSA-110056
Cilium Assembly R-HSA-5617833
G1/S Transition R-HSA-69206
Gene expression (Transcription) R-HSA-74160
Condensation of Prophase Chromosomes R-HSA-2299718
AURKA Activation by TPX2 R-HSA-8854518
Resolution of Sister Chromatid Cohesion R-HSA-2500257
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
Nuclear Envelope Breakdown R-HSA-2980766
Regulation of TP53 Degradation R-HSA-6804757
Centrosome maturation R-HSA-380287
Deubiquitination R-HSA-5688426
RNA Polymerase II Transcription R-HSA-73857
RAF-independent MAPK1/3 activation R-HSA-112409
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle Checkpoints R-HSA-69620
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Phosphorylation of Emi1 R-HSA-176417
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of TP53 Expression and Degradation R-HSA-6806003
G2/M Checkpoints R-HSA-69481
MAPK1/MAPK3 signaling R-HSA-5684996
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Mitotic Metaphase and Anaphase R-HSA-2555396
Transcriptional regulation by RUNX2 R-HSA-8878166
Phosphorylation of the APC/C R-HSA-176412
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Organelle biogenesis and maintenance R-HSA-1852241
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Loss of Nlp from mitotic centrosomes R-HSA-380259
Post-translational protein modification R-HSA-597592
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle R-HSA-1640170
Mitotic Anaphase R-HSA-68882
Mitotic Prophase R-HSA-68875
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
G2/M DNA damage checkpoint R-HSA-69473
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
G1/S-Specific Transcription R-HSA-69205
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Condensation of Prometaphase Chromosomes R-HSA-2514853
Ovarian tumor domain proteases R-HSA-5689896
Mitotic Prometaphase R-HSA-68877
Regulation of TP53 Activity R-HSA-5633007
MAPK family signaling cascades R-HSA-5683057
Mitotic G2-G2/M phases R-HSA-453274
Nuclear Envelope (NE) Reassembly R-HSA-2995410
MASTL Facilitates Mitotic Progression R-HSA-2465910
G2/M Transition R-HSA-69275
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Regulation of mitotic cell cycle R-HSA-453276
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional Regulation by TP53 R-HSA-3700989
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
G0 and Early G1 R-HSA-1538133
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic G1 phase and G1/S transition R-HSA-453279
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
E2F mediated regulation of DNA replication R-HSA-113510
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
G2/M DNA replication checkpoint R-HSA-69478
Regulation of TP53 Activity R-HSA-5633007
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Deubiquitination R-HSA-5688426
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Gene expression (Transcription) R-HSA-74160
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of TP53 Degradation R-HSA-6804757
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
RAF-independent MAPK1/3 activation R-HSA-112409
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Generic Transcription Pathway R-HSA-212436
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Mitotic G2-G2/M phases R-HSA-453274
G2/M DNA damage checkpoint R-HSA-69473
Cell Cycle R-HSA-1640170
Regulation of TP53 Expression and Degradation R-HSA-6806003
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Cilium Assembly R-HSA-5617833
Loss of Nlp from mitotic centrosomes R-HSA-380259
M Phase R-HSA-68886
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Metabolism of proteins R-HSA-392499
Phosphorylation of Emi1 R-HSA-176417
Organelle biogenesis and maintenance R-HSA-1852241
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Nuclear Envelope Breakdown R-HSA-2980766
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
MAPK3 (ERK1) activation R-HSA-110056
Depolymerisation of the Nuclear Lamina R-HSA-4419969
MASTL Facilitates Mitotic Progression R-HSA-2465910
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
E2F mediated regulation of DNA replication R-HSA-113510
MAPK family signaling cascades R-HSA-5683057
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Ovarian tumor domain proteases R-HSA-5689896
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Transcriptional regulation by RUNX2 R-HSA-8878166
AURKA Activation by TPX2 R-HSA-8854518
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
Condensation of Prophase Chromosomes R-HSA-2299718
G2/M Checkpoints R-HSA-69481
Transcriptional Regulation by TP53 R-HSA-3700989
G0 and Early G1 R-HSA-1538133
Mitotic Prophase R-HSA-68875
Signal Transduction R-HSA-162582
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic Prometaphase R-HSA-68877
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
G2/M DNA replication checkpoint R-HSA-69478
G1/S-Specific Transcription R-HSA-69205
Condensation of Prometaphase Chromosomes R-HSA-2514853
Centrosome maturation R-HSA-380287
G2/M Transition R-HSA-69275
MAPK6/MAPK4 signaling R-HSA-5687128
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Anaphase R-HSA-68882
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Post-translational protein modification R-HSA-597592
Phosphorylation of the APC/C R-HSA-176412
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Cell Cycle, Mitotic R-HSA-69278
Regulation of TP53 Degradation R-HSA-6804757
Cell Cycle, Mitotic R-HSA-69278
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Mitotic Prometaphase R-HSA-68877
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
RAF-independent MAPK1/3 activation R-HSA-112409
MAPK6/MAPK4 signaling R-HSA-5687128
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Phosphorylation of the APC/C R-HSA-176412
Regulation of TP53 Expression and Degradation R-HSA-6806003
Nuclear Envelope (NE) Reassembly R-HSA-2995410
AURKA Activation by TPX2 R-HSA-8854518
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Regulation of mitotic cell cycle R-HSA-453276
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Organelle biogenesis and maintenance R-HSA-1852241
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
MASTL Facilitates Mitotic Progression R-HSA-2465910
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Centrosome maturation R-HSA-380287
Mitotic Prophase R-HSA-68875
Cell Cycle Checkpoints R-HSA-69620
G2/M DNA replication checkpoint R-HSA-69478
Metabolism of proteins R-HSA-392499
G2/M Transition R-HSA-69275
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Nuclear Envelope Breakdown R-HSA-2980766
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Condensation of Prophase Chromosomes R-HSA-2299718
Regulation of TP53 Activity R-HSA-5633007
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Deubiquitination R-HSA-5688426
G2/M Checkpoints R-HSA-69481
Mitotic G2-G2/M phases R-HSA-453274
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
MAPK family signaling cascades R-HSA-5683057
G1/S-Specific Transcription R-HSA-69205
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Cell Cycle R-HSA-1640170
Condensation of Prometaphase Chromosomes R-HSA-2514853
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Transcriptional Regulation by TP53 R-HSA-3700989
G0 and Early G1 R-HSA-1538133
Cilium Assembly R-HSA-5617833
MAPK3 (ERK1) activation R-HSA-110056
Post-translational protein modification R-HSA-597592
G1/S Transition R-HSA-69206
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
M Phase R-HSA-68886
Loss of Nlp from mitotic centrosomes R-HSA-380259
G2/M DNA damage checkpoint R-HSA-69473
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
E2F mediated regulation of DNA replication R-HSA-113510
Gene expression (Transcription) R-HSA-74160
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Metaphase and Anaphase R-HSA-2555396
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX2 R-HSA-8878166
Ovarian tumor domain proteases R-HSA-5689896
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic G1 phase and G1/S transition R-HSA-453279
Phosphorylation of Emi1 R-HSA-176417
MAPK1/MAPK3 signaling R-HSA-5684996
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Mitotic Anaphase R-HSA-68882
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX2 R-HSA-8878166
G2/M DNA damage checkpoint R-HSA-69473
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Transcriptional Regulation by TP53 R-HSA-3700989
Cell Cycle Checkpoints R-HSA-69620
G1/S-Specific Transcription R-HSA-69205
Metabolism of proteins R-HSA-392499
Phosphorylation of the APC/C R-HSA-176412
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cilium Assembly R-HSA-5617833
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Mitotic G2-G2/M phases R-HSA-453274
Condensation of Prophase Chromosomes R-HSA-2299718
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Centrosome maturation R-HSA-380287
Cell Cycle, Mitotic R-HSA-69278
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Generic Transcription Pathway R-HSA-212436
Mitotic Prophase R-HSA-68875
Cell Cycle R-HSA-1640170
Nuclear Envelope (NE) Reassembly R-HSA-2995410
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Depolymerisation of the Nuclear Lamina R-HSA-4419969
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Nuclear Envelope Breakdown R-HSA-2980766
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
RNA Polymerase II Transcription R-HSA-73857
G2/M Transition R-HSA-69275
E2F mediated regulation of DNA replication R-HSA-113510
Mitotic Anaphase R-HSA-68882
Organelle biogenesis and maintenance R-HSA-1852241
Loss of Nlp from mitotic centrosomes R-HSA-380259
Gene expression (Transcription) R-HSA-74160
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
G2/M DNA replication checkpoint R-HSA-69478
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Ovarian tumor domain proteases R-HSA-5689896
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
MASTL Facilitates Mitotic Progression R-HSA-2465910
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Signal Transduction R-HSA-162582
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of TP53 Activity R-HSA-5633007
RAF-independent MAPK1/3 activation R-HSA-112409
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
Condensation of Prometaphase Chromosomes R-HSA-2514853
Regulation of TP53 Degradation R-HSA-6804757
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
G0 and Early G1 R-HSA-1538133
Mitotic Prometaphase R-HSA-68877
Post-translational protein modification R-HSA-597592
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Phosphorylation of Emi1 R-HSA-176417
Deubiquitination R-HSA-5688426
G1/S Transition R-HSA-69206
MAPK3 (ERK1) activation R-HSA-110056
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Regulation of mitotic cell cycle R-HSA-453276
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK1/MAPK3 signaling R-HSA-5684996
AURKA Activation by TPX2 R-HSA-8854518
G2/M DNA damage checkpoint R-HSA-69473
G2/M Checkpoints R-HSA-69481
G0 and Early G1 R-HSA-1538133
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Cell Cycle Checkpoints R-HSA-69620
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Deubiquitination R-HSA-5688426
Transcriptional Regulation by TP53 R-HSA-3700989
Depolymerisation of the Nuclear Lamina R-HSA-4419969
G2/M DNA replication checkpoint R-HSA-69478
Cilium Assembly R-HSA-5617833
Regulation of TP53 Expression and Degradation R-HSA-6806003
Mitotic Prometaphase R-HSA-68877
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Condensation of Prophase Chromosomes R-HSA-2299718
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Metabolism of proteins R-HSA-392499
RAF-independent MAPK1/3 activation R-HSA-112409
Regulation of TP53 Degradation R-HSA-6804757
Mitotic Prophase R-HSA-68875
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Cell Cycle, Mitotic R-HSA-69278
Mitotic Metaphase and Anaphase R-HSA-2555396
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Mitotic G1 phase and G1/S transition R-HSA-453279
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
G1/S Transition R-HSA-69206
Nuclear Envelope Breakdown R-HSA-2980766
MASTL Facilitates Mitotic Progression R-HSA-2465910
Loss of Nlp from mitotic centrosomes R-HSA-380259
Phosphorylation of the APC/C R-HSA-176412
G2/M Transition R-HSA-69275
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
E2F mediated regulation of DNA replication R-HSA-113510
Regulation of mitotic cell cycle R-HSA-453276
RNA Polymerase II Transcription R-HSA-73857
AURKA Activation by TPX2 R-HSA-8854518
Cell Cycle R-HSA-1640170
Organelle biogenesis and maintenance R-HSA-1852241
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK family signaling cascades R-HSA-5683057
G1/S-Specific Transcription R-HSA-69205
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Centrosome maturation R-HSA-380287
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ovarian tumor domain proteases R-HSA-5689896
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Anaphase R-HSA-68882
Post-translational protein modification R-HSA-597592
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Mitotic G2-G2/M phases R-HSA-453274
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Condensation of Prometaphase Chromosomes R-HSA-2514853
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Phosphorylation of Emi1 R-HSA-176417
MAPK3 (ERK1) activation R-HSA-110056
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Regulation of TP53 Activity R-HSA-5633007
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
MAPK1/MAPK3 signaling R-HSA-5684996
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Transcriptional regulation by RUNX2 R-HSA-8878166
Signal Transduction R-HSA-162582
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulation of mitotic cell cycle R-HSA-453276
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
RNA Polymerase II Transcription R-HSA-73857
Mitotic Prometaphase R-HSA-68877
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Deubiquitination R-HSA-5688426
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
AURKA Activation by TPX2 R-HSA-8854518
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Cell Cycle Checkpoints R-HSA-69620
G1/S Transition R-HSA-69206
Signal Transduction R-HSA-162582
RAF-independent MAPK1/3 activation R-HSA-112409
M Phase R-HSA-68886
E2F mediated regulation of DNA replication R-HSA-113510
Mitotic Prophase R-HSA-68875
Regulation of TP53 Expression and Degradation R-HSA-6806003
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Degradation R-HSA-6804757
MAPK3 (ERK1) activation R-HSA-110056
G2/M DNA replication checkpoint R-HSA-69478
MAPK family signaling cascades R-HSA-5683057
Mitotic G2-G2/M phases R-HSA-453274
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Mitotic Anaphase R-HSA-68882
Regulation of TP53 Activity R-HSA-5633007
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cilium Assembly R-HSA-5617833
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Post-translational protein modification R-HSA-597592
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Loss of Nlp from mitotic centrosomes R-HSA-380259
G2/M Transition R-HSA-69275
Nuclear Envelope (NE) Reassembly R-HSA-2995410
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Phosphorylation of the APC/C R-HSA-176412
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Anchoring of the basal body to the plasma membrane R-HSA-5620912
MAPK6/MAPK4 signaling R-HSA-5687128
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Phosphorylation of Emi1 R-HSA-176417
Transcriptional Regulation by TP53 R-HSA-3700989
MASTL Facilitates Mitotic Progression R-HSA-2465910
G0 and Early G1 R-HSA-1538133
Transcriptional regulation by RUNX2 R-HSA-8878166
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Resolution of Sister Chromatid Cohesion R-HSA-2500257
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
G1/S-Specific Transcription R-HSA-69205
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Centrosome maturation R-HSA-380287
Cell Cycle, Mitotic R-HSA-69278
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Nuclear Envelope Breakdown R-HSA-2980766
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Metabolism of proteins R-HSA-392499
G2/M Checkpoints R-HSA-69481
Organelle biogenesis and maintenance R-HSA-1852241
Condensation of Prometaphase Chromosomes R-HSA-2514853
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Condensation of Prophase Chromosomes R-HSA-2299718
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M DNA damage checkpoint R-HSA-69473
Ovarian tumor domain proteases R-HSA-5689896
MAPK1/MAPK3 signaling R-HSA-5684996
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Centrosome maturation R-HSA-380287
Metabolism of proteins R-HSA-392499
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Nuclear Envelope Breakdown R-HSA-2980766
AURKA Activation by TPX2 R-HSA-8854518
Cell Cycle R-HSA-1640170
Loss of Nlp from mitotic centrosomes R-HSA-380259
MASTL Facilitates Mitotic Progression R-HSA-2465910
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Mitotic G2-G2/M phases R-HSA-453274
G2/M Checkpoints R-HSA-69481
Ovarian tumor domain proteases R-HSA-5689896
Post-translational protein modification R-HSA-597592
MAPK6/MAPK4 signaling R-HSA-5687128
Cilium Assembly R-HSA-5617833
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
G2/M DNA replication checkpoint R-HSA-69478
Resolution of Sister Chromatid Cohesion R-HSA-2500257
G0 and Early G1 R-HSA-1538133
Mitotic Prophase R-HSA-68875
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of TP53 Activity R-HSA-5633007
M Phase R-HSA-68886
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Prometaphase R-HSA-68877
Signal Transduction R-HSA-162582
Condensation of Prometaphase Chromosomes R-HSA-2514853
Phosphorylation of the APC/C R-HSA-176412
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
RAF-independent MAPK1/3 activation R-HSA-112409
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Deubiquitination R-HSA-5688426
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
Organelle biogenesis and maintenance R-HSA-1852241
G1/S-Specific Transcription R-HSA-69205
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Mitotic G1 phase and G1/S transition R-HSA-453279
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulation of TP53 Expression and Degradation R-HSA-6806003
G2/M DNA damage checkpoint R-HSA-69473
MAPK family signaling cascades R-HSA-5683057
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic Anaphase R-HSA-68882
RNA Polymerase II Transcription R-HSA-73857
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle Checkpoints R-HSA-69620
MAPK3 (ERK1) activation R-HSA-110056
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of TP53 Degradation R-HSA-6804757
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Transcriptional Regulation by TP53 R-HSA-3700989
G1/S Transition R-HSA-69206
Condensation of Prophase Chromosomes R-HSA-2299718
Phosphorylation of Emi1 R-HSA-176417
E2F mediated regulation of DNA replication R-HSA-113510
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of mitotic cell cycle R-HSA-453276
G2/M Transition R-HSA-69275
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Organelle biogenesis and maintenance R-HSA-1852241
MAPK3 (ERK1) activation R-HSA-110056
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of TP53 Degradation R-HSA-6804757
Ovarian tumor domain proteases R-HSA-5689896
RAF-independent MAPK1/3 activation R-HSA-112409
G0 and Early G1 R-HSA-1538133
G2/M DNA replication checkpoint R-HSA-69478
Signal Transduction R-HSA-162582
Nuclear Envelope (NE) Reassembly R-HSA-2995410
E2F mediated regulation of DNA replication R-HSA-113510
G1/S Transition R-HSA-69206
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Depolymerisation of the Nuclear Lamina R-HSA-4419969
G1/S-Specific Transcription R-HSA-69205
M Phase R-HSA-68886
Post-translational protein modification R-HSA-597592
Cell Cycle R-HSA-1640170
Cell Cycle Checkpoints R-HSA-69620
G2/M Transition R-HSA-69275
Regulation of TP53 Expression and Degradation R-HSA-6806003
Mitotic Anaphase R-HSA-68882
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Deubiquitination R-HSA-5688426
Condensation of Prophase Chromosomes R-HSA-2299718
Regulation of TP53 Activity R-HSA-5633007
Phosphorylation of the APC/C R-HSA-176412
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Mitotic G1 phase and G1/S transition R-HSA-453279
Condensation of Prometaphase Chromosomes R-HSA-2514853
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Loss of Nlp from mitotic centrosomes R-HSA-380259
Mitotic Prometaphase R-HSA-68877
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Centrosome maturation R-HSA-380287
Regulation of mitotic cell cycle R-HSA-453276
Cilium Assembly R-HSA-5617833
MAPK1/MAPK3 signaling R-HSA-5684996
MASTL Facilitates Mitotic Progression R-HSA-2465910
Transcriptional Regulation by TP53 R-HSA-3700989
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
MAPK6/MAPK4 signaling R-HSA-5687128
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX2 R-HSA-8878166
G2/M DNA damage checkpoint R-HSA-69473
Mitotic G2-G2/M phases R-HSA-453274
Gene expression (Transcription) R-HSA-74160
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Mitotic Prophase R-HSA-68875
MAPK family signaling cascades R-HSA-5683057
AURKA Activation by TPX2 R-HSA-8854518
Mitotic Metaphase and Anaphase R-HSA-2555396
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Nuclear Envelope Breakdown R-HSA-2980766
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Phosphorylation of Emi1 R-HSA-176417
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
G2/M Checkpoints R-HSA-69481

Expression Atlas ENSG00000170312
NCBI gene (formerly Entrezgene) 983
GeneCards 1722
HGNC Symbol HGNC:1722
MIM gene 116940
UniProtKB Gene Name P06493
WikiGene 983
Gene: PAK4
Ensembl ID : ENSG00000130669
Description: p21 (RAC1) activated kinase 4
Gene Synonyms:
1 APIs:
160 Possible Orthologues:

RHOV GTPase cycle R-HSA-9013424
RHOH GTPase cycle R-HSA-9013407
Developmental Biology R-HSA-1266738
RAC1 GTPase cycle R-HSA-9013149
Axon guidance R-HSA-422475
Activation of RAC1 R-HSA-428540
RAC2 GTPase cycle R-HSA-9013404
RHO GTPase cycle R-HSA-9012999
Nervous system development R-HSA-9675108
RHOJ GTPase cycle R-HSA-9013409
RHOU GTPase cycle R-HSA-9013420
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Rho GTPases R-HSA-194315
RHOQ GTPase cycle R-HSA-9013406
Signal Transduction R-HSA-162582
CDC42 GTPase cycle R-HSA-9013148
RAC3 GTPase cycle R-HSA-9013423
RHOG GTPase cycle R-HSA-9013408
Signaling by ROBO receptors R-HSA-376176
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RAC2 GTPase cycle R-HSA-9013404
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
RHOV GTPase cycle R-HSA-9013424
RHOG GTPase cycle R-HSA-9013408
RHO GTPase cycle R-HSA-9012999
Developmental Biology R-HSA-1266738
Activation of RAC1 R-HSA-428540
CDC42 GTPase cycle R-HSA-9013148
RHOU GTPase cycle R-HSA-9013420
RAC1 GTPase cycle R-HSA-9013149
RHOJ GTPase cycle R-HSA-9013409
Signaling by ROBO receptors R-HSA-376176
RHOH GTPase cycle R-HSA-9013407
RHOQ GTPase cycle R-HSA-9013406
RAC3 GTPase cycle R-HSA-9013423
Signaling by Rho GTPases R-HSA-194315
RHOJ GTPase cycle R-HSA-9013409
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RAC3 GTPase cycle R-HSA-9013423
Signaling by Rho GTPases R-HSA-194315
RHOG GTPase cycle R-HSA-9013408
RHOV GTPase cycle R-HSA-9013424
CDC42 GTPase cycle R-HSA-9013148
Signal Transduction R-HSA-162582
RAC2 GTPase cycle R-HSA-9013404
RHO GTPase cycle R-HSA-9012999
Nervous system development R-HSA-9675108
RHOQ GTPase cycle R-HSA-9013406
RHOU GTPase cycle R-HSA-9013420
Activation of RAC1 R-HSA-428540
Signaling by ROBO receptors R-HSA-376176
RHOH GTPase cycle R-HSA-9013407
Axon guidance R-HSA-422475
RAC1 GTPase cycle R-HSA-9013149
Axon guidance R-HSA-422475
RHOJ GTPase cycle R-HSA-9013409
RHO GTPase cycle R-HSA-9012999
Activation of RAC1 R-HSA-428540
RAC1 GTPase cycle R-HSA-9013149
RAC3 GTPase cycle R-HSA-9013423
RHOG GTPase cycle R-HSA-9013408
RHOH GTPase cycle R-HSA-9013407
Signaling by Rho GTPases R-HSA-194315
Nervous system development R-HSA-9675108
RAC2 GTPase cycle R-HSA-9013404
Signal Transduction R-HSA-162582
Signaling by ROBO receptors R-HSA-376176
Developmental Biology R-HSA-1266738
RHOV GTPase cycle R-HSA-9013424
CDC42 GTPase cycle R-HSA-9013148
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHOU GTPase cycle R-HSA-9013420
RHOQ GTPase cycle R-HSA-9013406
Signal Transduction R-HSA-162582
CDC42 GTPase cycle R-HSA-9013148
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RAC2 GTPase cycle R-HSA-9013404
RHOH GTPase cycle R-HSA-9013407
Activation of RAC1 R-HSA-428540
Signaling by Rho GTPases R-HSA-194315
RAC1 GTPase cycle R-HSA-9013149
RHOG GTPase cycle R-HSA-9013408
RHOV GTPase cycle R-HSA-9013424
RHOU GTPase cycle R-HSA-9013420
RHOJ GTPase cycle R-HSA-9013409
RAC3 GTPase cycle R-HSA-9013423
RHO GTPase cycle R-HSA-9012999
Developmental Biology R-HSA-1266738
Signaling by ROBO receptors R-HSA-376176
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
RHOQ GTPase cycle R-HSA-9013406
RAC3 GTPase cycle R-HSA-9013423
Signaling by ROBO receptors R-HSA-376176
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
Signaling by Rho GTPases R-HSA-194315
CDC42 GTPase cycle R-HSA-9013148
RAC1 GTPase cycle R-HSA-9013149
RHOJ GTPase cycle R-HSA-9013409
RHOU GTPase cycle R-HSA-9013420
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Activation of RAC1 R-HSA-428540
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
RHOV GTPase cycle R-HSA-9013424
RHOQ GTPase cycle R-HSA-9013406
RAC2 GTPase cycle R-HSA-9013404
RHOH GTPase cycle R-HSA-9013407
RHO GTPase cycle R-HSA-9012999
RHOG GTPase cycle R-HSA-9013408
RHO GTPase cycle R-HSA-9012999
CDC42 GTPase cycle R-HSA-9013148
RHOQ GTPase cycle R-HSA-9013406
Activation of RAC1 R-HSA-428540
RHOG GTPase cycle R-HSA-9013408
RHOH GTPase cycle R-HSA-9013407
RHOU GTPase cycle R-HSA-9013420
Signal Transduction R-HSA-162582
RAC2 GTPase cycle R-HSA-9013404
RAC1 GTPase cycle R-HSA-9013149
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Signaling by ROBO receptors R-HSA-376176
Signaling by Rho GTPases R-HSA-194315
Nervous system development R-HSA-9675108
RHOJ GTPase cycle R-HSA-9013409
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHOV GTPase cycle R-HSA-9013424
RAC3 GTPase cycle R-HSA-9013423
Axon guidance R-HSA-422475
RHOQ GTPase cycle R-HSA-9013406
RHOH GTPase cycle R-HSA-9013407
CDC42 GTPase cycle R-HSA-9013148
Nervous system development R-HSA-9675108
Activation of RAC1 R-HSA-428540
RAC3 GTPase cycle R-HSA-9013423
Signal Transduction R-HSA-162582
Signaling by ROBO receptors R-HSA-376176
RHOV GTPase cycle R-HSA-9013424
RHOG GTPase cycle R-HSA-9013408
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase cycle R-HSA-9012999
RHOJ GTPase cycle R-HSA-9013409
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases R-HSA-194315
RAC1 GTPase cycle R-HSA-9013149
RHOU GTPase cycle R-HSA-9013420
RAC2 GTPase cycle R-HSA-9013404
Axon guidance R-HSA-422475
RHOU GTPase cycle R-HSA-9013420
RAC1 GTPase cycle R-HSA-9013149
Signaling by ROBO receptors R-HSA-376176
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Rho GTPases R-HSA-194315
Developmental Biology R-HSA-1266738
RHOJ GTPase cycle R-HSA-9013409
Activation of RAC1 R-HSA-428540
Signal Transduction R-HSA-162582
RHOH GTPase cycle R-HSA-9013407
RHOQ GTPase cycle R-HSA-9013406
RAC2 GTPase cycle R-HSA-9013404
RHOG GTPase cycle R-HSA-9013408
RAC3 GTPase cycle R-HSA-9013423
RHO GTPase cycle R-HSA-9012999
CDC42 GTPase cycle R-HSA-9013148
RHOV GTPase cycle R-HSA-9013424
Nervous system development R-HSA-9675108

Expression Atlas ENSG00000130669
NCBI gene (formerly Entrezgene) 10298
GeneCards 16059
HGNC Symbol HGNC:16059
MIM gene 605451
UniProtKB Gene Name O96013
WikiGene 10298
Gene: MAPK8
Ensembl ID : ENSG00000107643
Description: mitogen-activated protein kinase 8
Gene Synonyms: JNK,JNK1,PRKM8,SAPK1
3 APIs:
292 Possible Orthologues:

Cellular responses to stress R-HSA-2262752
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
DSCAM interactions R-HSA-376172
Disease R-HSA-1643685
Innate Immune System R-HSA-168249
DNA Double-Strand Break Repair R-HSA-5693532
Infectious disease R-HSA-5663205
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular responses to stimuli R-HSA-8953897
Activation of BMF and translocation to mitochondria R-HSA-139910
Activation of BIM and translocation to mitochondria R-HSA-111446
Killing mechanisms R-HSA-9664420
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
NRAGE signals death through JNK R-HSA-193648
Nervous system development R-HSA-9675108
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Axon guidance R-HSA-422475
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Programmed Cell Death R-HSA-5357801
Toll-like Receptor Cascades R-HSA-168898
Cytokine Signaling in Immune system R-HSA-1280215
DNA Double Strand Break Response R-HSA-5693606
Interleukin-1 family signaling R-HSA-446652
Netrin-1 signaling R-HSA-373752
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Activation of the AP-1 family of transcription factors R-HSA-450341
Developmental Biology R-HSA-1266738
Intrinsic Pathway for Apoptosis R-HSA-109606
DNA Repair R-HSA-73894
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88 cascade initiated on plasma membrane R-HSA-975871
Immune System R-HSA-168256
Leishmania infection R-HSA-9658195
Apoptosis R-HSA-109581
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular Senescence R-HSA-2559583
MyD88 dependent cascade initiated on endosome R-HSA-975155
MAP kinase activation R-HSA-450294
FCERI mediated MAPK activation R-HSA-2871796
Activation of BH3-only proteins R-HSA-114452
p75 NTR receptor-mediated signalling R-HSA-193704
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Interleukin-38 signaling R-HSA-9007892
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Death Receptor Signaling R-HSA-73887
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
NRIF signals cell death from the nucleus R-HSA-205043
Signal Transduction R-HSA-162582
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583
Activation of BH3-only proteins R-HSA-114452
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by Interleukins R-HSA-449147
Nervous system development R-HSA-9675108
NRIF signals cell death from the nucleus R-HSA-205043
FCERI mediated MAPK activation R-HSA-2871796
DNA Repair R-HSA-73894
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Infectious disease R-HSA-5663205
DNA Double-Strand Break Repair R-HSA-5693532
Netrin-1 signaling R-HSA-373752
Activation of BIM and translocation to mitochondria R-HSA-111446
Immune System R-HSA-168256
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
NRAGE signals death through JNK R-HSA-193648
Cellular responses to stress R-HSA-2262752
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Programmed Cell Death R-HSA-5357801
Death Receptor Signaling R-HSA-73887
Leishmania infection R-HSA-9658195
Interleukin-1 family signaling R-HSA-446652
Interleukin-38 signaling R-HSA-9007892
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Intrinsic Pathway for Apoptosis R-HSA-109606
MyD88 cascade initiated on plasma membrane R-HSA-975871
MAP kinase activation R-HSA-450294
Killing mechanisms R-HSA-9664420
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Developmental Biology R-HSA-1266738
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Activation of BMF and translocation to mitochondria R-HSA-139910
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Activation of the AP-1 family of transcription factors R-HSA-450341
Innate Immune System R-HSA-168249
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
p75 NTR receptor-mediated signalling R-HSA-193704
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Axon guidance R-HSA-422475
Apoptosis R-HSA-109581
MyD88 dependent cascade initiated on endosome R-HSA-975155
DSCAM interactions R-HSA-376172
DNA Double Strand Break Response R-HSA-5693606
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll-like Receptor Cascades R-HSA-168898
Cellular responses to stimuli R-HSA-8953897
Innate Immune System R-HSA-168249
MyD88 cascade initiated on plasma membrane R-HSA-975871
DSCAM interactions R-HSA-376172
Infectious disease R-HSA-5663205
NRAGE signals death through JNK R-HSA-193648
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
NRIF signals cell death from the nucleus R-HSA-205043
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cytokine Signaling in Immune system R-HSA-1280215
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Interleukins R-HSA-449147
DNA Double Strand Break Response R-HSA-5693606
MyD88-independent TLR4 cascade R-HSA-166166
Cellular responses to stress R-HSA-2262752
DNA Repair R-HSA-73894
Netrin-1 signaling R-HSA-373752
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Cellular responses to stimuli R-HSA-8953897
Disease R-HSA-1643685
Activation of the AP-1 family of transcription factors R-HSA-450341
Cellular Senescence R-HSA-2559583
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Intrinsic Pathway for Apoptosis R-HSA-109606
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Activation of BMF and translocation to mitochondria R-HSA-139910
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
DNA Double-Strand Break Repair R-HSA-5693532
Activation of BIM and translocation to mitochondria R-HSA-111446
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
Interleukin-1 family signaling R-HSA-446652
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
FCERI mediated MAPK activation R-HSA-2871796
Apoptosis R-HSA-109581
Nervous system development R-HSA-9675108
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Activation of BH3-only proteins R-HSA-114452
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Leishmania infection R-HSA-9658195
Immune System R-HSA-168256
Interleukin-38 signaling R-HSA-9007892
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Death Receptor Signaling R-HSA-73887
Programmed Cell Death R-HSA-5357801
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MAP kinase activation R-HSA-450294
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Developmental Biology R-HSA-1266738
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Killing mechanisms R-HSA-9664420
Killing mechanisms R-HSA-9664420
Activation of BIM and translocation to mitochondria R-HSA-111446
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Disease R-HSA-1643685
MyD88 dependent cascade initiated on endosome R-HSA-975155
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
DNA Double-Strand Break Repair R-HSA-5693532
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll-like Receptor Cascades R-HSA-168898
Netrin-1 signaling R-HSA-373752
MAP kinase activation R-HSA-450294
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Cellular Senescence R-HSA-2559583
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Oxidative Stress Induced Senescence R-HSA-2559580
Infectious disease R-HSA-5663205
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Activation of BMF and translocation to mitochondria R-HSA-139910
NRAGE signals death through JNK R-HSA-193648
Cellular responses to stress R-HSA-2262752
Intrinsic Pathway for Apoptosis R-HSA-109606
Apoptosis R-HSA-109581
Interleukin-38 signaling R-HSA-9007892
DNA Double Strand Break Response R-HSA-5693606
Leishmania infection R-HSA-9658195
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Activation of BH3-only proteins R-HSA-114452
DSCAM interactions R-HSA-376172
Interleukin-17 signaling R-HSA-448424
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
DNA Repair R-HSA-73894
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
FCERI mediated MAPK activation R-HSA-2871796
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
NRIF signals cell death from the nucleus R-HSA-205043
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Nervous system development R-HSA-9675108
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cytokine Signaling in Immune system R-HSA-1280215
Activation of the AP-1 family of transcription factors R-HSA-450341
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Developmental Biology R-HSA-1266738
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Programmed Cell Death R-HSA-5357801
Cellular Senescence R-HSA-2559583
Axon guidance R-HSA-422475
Oxidative Stress Induced Senescence R-HSA-2559580
Death Receptor Signaling R-HSA-73887
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
DNA Repair R-HSA-73894
Nervous system development R-HSA-9675108
Cellular responses to stress R-HSA-2262752
Netrin-1 signaling R-HSA-373752
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Innate Immune System R-HSA-168249
Activation of BIM and translocation to mitochondria R-HSA-111446
Programmed Cell Death R-HSA-5357801
Signal Transduction R-HSA-162582
Killing mechanisms R-HSA-9664420
Immune System R-HSA-168256
FCERI mediated MAPK activation R-HSA-2871796
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Apoptosis R-HSA-109581
Interleukin-17 signaling R-HSA-448424
MyD88-independent TLR4 cascade R-HSA-166166
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Leishmania infection R-HSA-9658195
Cytokine Signaling in Immune system R-HSA-1280215
NRAGE signals death through JNK R-HSA-193648
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
p75 NTR receptor-mediated signalling R-HSA-193704
MyD88 dependent cascade initiated on endosome R-HSA-975155
MAP kinase activation R-HSA-450294
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Intrinsic Pathway for Apoptosis R-HSA-109606
Disease R-HSA-1643685
Interleukin-38 signaling R-HSA-9007892
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll-like Receptor Cascades R-HSA-168898
Signaling by Interleukins R-HSA-449147
NRIF signals cell death from the nucleus R-HSA-205043
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of BMF and translocation to mitochondria R-HSA-139910
Developmental Biology R-HSA-1266738
DNA Double-Strand Break Repair R-HSA-5693532
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Infectious disease R-HSA-5663205
Activation of BH3-only proteins R-HSA-114452
Activation of the AP-1 family of transcription factors R-HSA-450341
Cellular responses to stimuli R-HSA-8953897
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
DNA Double Strand Break Response R-HSA-5693606
DSCAM interactions R-HSA-376172
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Signaling by Interleukins R-HSA-449147
Leishmania infection R-HSA-9658195
DNA Double-Strand Break Repair R-HSA-5693532
Activation of BMF and translocation to mitochondria R-HSA-139910
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
NRAGE signals death through JNK R-HSA-193648
Toll-like Receptor Cascades R-HSA-168898
Activation of the AP-1 family of transcription factors R-HSA-450341
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Interleukin-17 signaling R-HSA-448424
Netrin-1 signaling R-HSA-373752
MyD88 cascade initiated on plasma membrane R-HSA-975871
Axon guidance R-HSA-422475
Cellular Senescence R-HSA-2559583
Activation of BH3-only proteins R-HSA-114452
Apoptosis R-HSA-109581
Interleukin-38 signaling R-HSA-9007892
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Cytokine Signaling in Immune system R-HSA-1280215
MAP kinase activation R-HSA-450294
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Interleukin-1 family signaling R-HSA-446652
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88-independent TLR4 cascade R-HSA-166166
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Developmental Biology R-HSA-1266738
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
p75 NTR receptor-mediated signalling R-HSA-193704
DNA Repair R-HSA-73894
Intrinsic Pathway for Apoptosis R-HSA-109606
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Programmed Cell Death R-HSA-5357801
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stress R-HSA-2262752
Immune System R-HSA-168256
Killing mechanisms R-HSA-9664420
Nervous system development R-HSA-9675108
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Activation of BIM and translocation to mitochondria R-HSA-111446
DSCAM interactions R-HSA-376172
NRIF signals cell death from the nucleus R-HSA-205043
Infectious disease R-HSA-5663205
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Disease R-HSA-1643685
DNA Double Strand Break Response R-HSA-5693606
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
DNA Repair R-HSA-73894
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Innate Immune System R-HSA-168249
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by Interleukins R-HSA-449147
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Leishmania infection R-HSA-9658195
NRAGE signals death through JNK R-HSA-193648
Interleukin-38 signaling R-HSA-9007892
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Immune System R-HSA-168256
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DNA Double Strand Break Response R-HSA-5693606
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MyD88 dependent cascade initiated on endosome R-HSA-975155
Netrin-1 signaling R-HSA-373752
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Interleukin-1 family signaling R-HSA-446652
MyD88-independent TLR4 cascade R-HSA-166166
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
MAP kinase activation R-HSA-450294
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
DSCAM interactions R-HSA-376172
Apoptosis R-HSA-109581
Disease R-HSA-1643685
DNA Double-Strand Break Repair R-HSA-5693532
FCERI mediated MAPK activation R-HSA-2871796
Nervous system development R-HSA-9675108
Activation of BIM and translocation to mitochondria R-HSA-111446
Activation of BMF and translocation to mitochondria R-HSA-139910
NRIF signals cell death from the nucleus R-HSA-205043
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Programmed Cell Death R-HSA-5357801
Interleukin-17 signaling R-HSA-448424
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Killing mechanisms R-HSA-9664420
Cytokine Signaling in Immune system R-HSA-1280215
Cellular Senescence R-HSA-2559583
Activation of the AP-1 family of transcription factors R-HSA-450341
Oxidative Stress Induced Senescence R-HSA-2559580
Activation of BH3-only proteins R-HSA-114452
Cellular responses to stress R-HSA-2262752
Toll-like Receptor Cascades R-HSA-168898
Infectious disease R-HSA-5663205
Killing mechanisms R-HSA-9664420
Developmental Biology R-HSA-1266738
Intrinsic Pathway for Apoptosis R-HSA-109606
Interleukin-38 signaling R-HSA-9007892
p75 NTR receptor-mediated signalling R-HSA-193704
Cellular Senescence R-HSA-2559583
Activation of BMF and translocation to mitochondria R-HSA-139910
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Nervous system development R-HSA-9675108
DNA Repair R-HSA-73894
Programmed Cell Death R-HSA-5357801
Cellular responses to stress R-HSA-2262752
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Innate Immune System R-HSA-168249
Leishmania infection R-HSA-9658195
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Axon guidance R-HSA-422475
Netrin-1 signaling R-HSA-373752
Oxidative Stress Induced Senescence R-HSA-2559580
Disease R-HSA-1643685
DNA Double Strand Break Response R-HSA-5693606
DSCAM interactions R-HSA-376172
Cellular responses to stimuli R-HSA-8953897
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
FCERI mediated MAPK activation R-HSA-2871796
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
MyD88-independent TLR4 cascade R-HSA-166166
MAP kinase activation R-HSA-450294
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
NRIF signals cell death from the nucleus R-HSA-205043
DNA Double-Strand Break Repair R-HSA-5693532
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll-like Receptor Cascades R-HSA-168898
MyD88 dependent cascade initiated on endosome R-HSA-975155
Activation of BH3-only proteins R-HSA-114452
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Interleukin-17 signaling R-HSA-448424
Death Receptor Signaling R-HSA-73887
Activation of BIM and translocation to mitochondria R-HSA-111446
Interleukin-1 family signaling R-HSA-446652
Activation of the AP-1 family of transcription factors R-HSA-450341
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal Transduction R-HSA-162582
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Immune System R-HSA-168256
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
NRAGE signals death through JNK R-HSA-193648
Apoptosis R-HSA-109581
Killing mechanisms R-HSA-9664420
NRIF signals cell death from the nucleus R-HSA-205043
NRAGE signals death through JNK R-HSA-193648
p75 NTR receptor-mediated signalling R-HSA-193704
Activation of the AP-1 family of transcription factors R-HSA-450341
Immune System R-HSA-168256
DNA Double Strand Break Response R-HSA-5693606
MAP kinase activation R-HSA-450294
Activation of BH3-only proteins R-HSA-114452
Activation of BIM and translocation to mitochondria R-HSA-111446
Death Receptor Signaling R-HSA-73887
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by Interleukins R-HSA-449147
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
MyD88 cascade initiated on plasma membrane R-HSA-975871
Infectious disease R-HSA-5663205
Oxidative Stress Induced Senescence R-HSA-2559580
Programmed Cell Death R-HSA-5357801
Intrinsic Pathway for Apoptosis R-HSA-109606
Axon guidance R-HSA-422475
FCERI mediated MAPK activation R-HSA-2871796
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Activation of BMF and translocation to mitochondria R-HSA-139910
Interleukin-17 signaling R-HSA-448424
Disease R-HSA-1643685
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signal Transduction R-HSA-162582
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Nervous system development R-HSA-9675108
Leishmania infection R-HSA-9658195
Developmental Biology R-HSA-1266738
Interleukin-38 signaling R-HSA-9007892
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular Senescence R-HSA-2559583
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DNA Double-Strand Break Repair R-HSA-5693532
Apoptosis R-HSA-109581
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
DSCAM interactions R-HSA-376172
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Toll-like Receptor Cascades R-HSA-168898
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Cellular responses to stress R-HSA-2262752
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
DNA Repair R-HSA-73894
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Netrin-1 signaling R-HSA-373752
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Innate Immune System R-HSA-168249
Activation of BMF and translocation to mitochondria R-HSA-139910
Activation of BIM and translocation to mitochondria R-HSA-111446
Interleukin-1 family signaling R-HSA-446652
p75 NTR receptor-mediated signalling R-HSA-193704
Innate Immune System R-HSA-168249
Cellular responses to stress R-HSA-2262752
Activation of BH3-only proteins R-HSA-114452
Activation of the AP-1 family of transcription factors R-HSA-450341
DNA Double-Strand Break Repair R-HSA-5693532
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Interleukins R-HSA-449147
DNA Repair R-HSA-73894
Netrin-1 signaling R-HSA-373752
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll-like Receptor Cascades R-HSA-168898
NRAGE signals death through JNK R-HSA-193648
Disease R-HSA-1643685
MAP kinase activation R-HSA-450294
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Leishmania infection R-HSA-9658195
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
DSCAM interactions R-HSA-376172
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Killing mechanisms R-HSA-9664420
Intrinsic Pathway for Apoptosis R-HSA-109606
DNA Double Strand Break Response R-HSA-5693606
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal Transduction R-HSA-162582
MyD88-independent TLR4 cascade R-HSA-166166
Cellular Senescence R-HSA-2559583
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-38 signaling R-HSA-9007892
Apoptosis R-HSA-109581
NRIF signals cell death from the nucleus R-HSA-205043
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Programmed Cell Death R-HSA-5357801
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Nervous system development R-HSA-9675108
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Infectious disease R-HSA-5663205
Immune System R-HSA-168256
Developmental Biology R-HSA-1266738
Death Receptor Signaling R-HSA-73887
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88 dependent cascade initiated on endosome R-HSA-975155
Axon guidance R-HSA-422475
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-17 signaling R-HSA-448424
WNT5:FZD7-mediated leishmania damping R-HSA-9673324

Expression Atlas ENSG00000107643
NCBI gene (formerly Entrezgene) 5599
GeneCards 6881
HGNC Symbol HGNC:6881
MIM gene 601158
UniProtKB Gene Name P45983
WikiGene 5599
Gene: EML4
Ensembl ID : ENSG00000143924
Description: EMAP like 4
Gene Synonyms: C2ORF2,ELP120,ROPP120
5 APIs:
214 Possible Orthologues:

ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK in cancer R-HSA-9700206
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Mitotic Prometaphase R-HSA-68877
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
ALK mutants bind TKIs R-HSA-9700645
Disease R-HSA-1643685
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK fusions and activated point mutants R-HSA-9725370
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Cell Cycle R-HSA-1640170
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
M Phase R-HSA-68886
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Cell Cycle, Mitotic R-HSA-69278
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Mitotic Prometaphase R-HSA-68877
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
ALK mutants bind TKIs R-HSA-9700645
M Phase R-HSA-68886
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK in cancer R-HSA-9700206
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Cell Cycle, Mitotic R-HSA-69278
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
ALK mutants bind TKIs R-HSA-9700645
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Mitotic Prometaphase R-HSA-68877
Cell Cycle, Mitotic R-HSA-69278
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
ALK mutants bind TKIs R-HSA-9700645
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by ALK in cancer R-HSA-9700206
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Signaling by ALK in cancer R-HSA-9700206
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Disease R-HSA-1643685
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Cell Cycle R-HSA-1640170
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
M Phase R-HSA-68886

Expression Atlas ENSG00000143924
NCBI gene (formerly Entrezgene) 27436
GeneCards 1316
HGNC Symbol HGNC:1316
MIM gene 607442
UniProtKB Gene Name Q9HC35
WikiGene 27436
Gene: PPP3CA
Ensembl ID : ENSG00000138814
Description: protein phosphatase 3 catalytic subunit alpha
Gene Synonyms: CALN,CALNA,CNA1,PPP2B
1 APIs:
230 Possible Orthologues:

GPCR downstream signalling R-HSA-388396
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Ca2+ pathway R-HSA-4086398
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Calcineurin activates NFAT R-HSA-2025928
C-type lectin receptors (CLRs) R-HSA-5621481
CLEC7A (Dectin-1) signaling R-HSA-5607764
FCERI mediated Ca+2 mobilization R-HSA-2871809
DARPP-32 events R-HSA-180024
Beta-catenin independent WNT signaling R-HSA-3858494
Opioid Signalling R-HSA-111885
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Adaptive Immune System R-HSA-1280218
G alpha (i) signalling events R-HSA-418594
Signaling by WNT R-HSA-195721
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ca2+ pathway R-HSA-4086398
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by GPCR R-HSA-372790
FCERI mediated Ca+2 mobilization R-HSA-2871809
Signal Transduction R-HSA-162582
DARPP-32 events R-HSA-180024
G alpha (i) signalling events R-HSA-418594
Opioid Signalling R-HSA-111885
GPCR downstream signalling R-HSA-388396
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Calcineurin activates NFAT R-HSA-2025928
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by WNT R-HSA-195721
C-type lectin receptors (CLRs) R-HSA-5621481
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by the B Cell Receptor (BCR) R-HSA-983705
CLEC7A (Dectin-1) signaling R-HSA-5607764
C-type lectin receptors (CLRs) R-HSA-5621481
Adaptive Immune System R-HSA-1280218
Signaling by WNT R-HSA-195721
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Immune System R-HSA-168256
Beta-catenin independent WNT signaling R-HSA-3858494
Innate Immune System R-HSA-168249
Ca2+ pathway R-HSA-4086398
DARPP-32 events R-HSA-180024
Opioid Signalling R-HSA-111885
Signal Transduction R-HSA-162582
Calcineurin activates NFAT R-HSA-2025928
G alpha (i) signalling events R-HSA-418594
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated Ca+2 mobilization R-HSA-2871809
Beta-catenin independent WNT signaling R-HSA-3858494
Immune System R-HSA-168256
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
DARPP-32 events R-HSA-180024
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Opioid Signalling R-HSA-111885
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ca2+ pathway R-HSA-4086398
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
Calcineurin activates NFAT R-HSA-2025928
Signaling by WNT R-HSA-195721
CLEC7A (Dectin-1) signaling R-HSA-5607764
C-type lectin receptors (CLRs) R-HSA-5621481
FCERI mediated Ca+2 mobilization R-HSA-2871809
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by GPCR R-HSA-372790
Beta-catenin independent WNT signaling R-HSA-3858494
Opioid Signalling R-HSA-111885
Ca2+ pathway R-HSA-4086398
Signal Transduction R-HSA-162582
DARPP-32 events R-HSA-180024
G alpha (i) signalling events R-HSA-418594
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
GPCR downstream signalling R-HSA-388396
FCERI mediated Ca+2 mobilization R-HSA-2871809
Calcineurin activates NFAT R-HSA-2025928
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by WNT R-HSA-195721
Immune System R-HSA-168256
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by WNT R-HSA-195721
CLEC7A (Dectin-1) signaling R-HSA-5607764
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Immune System R-HSA-168256
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
FCERI mediated Ca+2 mobilization R-HSA-2871809
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by GPCR R-HSA-372790
Innate Immune System R-HSA-168249
DARPP-32 events R-HSA-180024
C-type lectin receptors (CLRs) R-HSA-5621481
Ca2+ pathway R-HSA-4086398
Signaling by the B Cell Receptor (BCR) R-HSA-983705
GPCR downstream signalling R-HSA-388396
Beta-catenin independent WNT signaling R-HSA-3858494
Calcineurin activates NFAT R-HSA-2025928
Opioid Signalling R-HSA-111885
Adaptive Immune System R-HSA-1280218
Ca2+ pathway R-HSA-4086398
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Opioid Signalling R-HSA-111885
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
FCERI mediated Ca+2 mobilization R-HSA-2871809
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Calcineurin activates NFAT R-HSA-2025928
Signaling by WNT R-HSA-195721
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Innate Immune System R-HSA-168249
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Beta-catenin independent WNT signaling R-HSA-3858494
DARPP-32 events R-HSA-180024
GPCR downstream signalling R-HSA-388396
Ca2+ pathway R-HSA-4086398
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
G alpha (i) signalling events R-HSA-418594
Immune System R-HSA-168256
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Opioid Signalling R-HSA-111885
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FCERI mediated Ca+2 mobilization R-HSA-2871809
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
GPCR downstream signalling R-HSA-388396
Adaptive Immune System R-HSA-1280218
Calcineurin activates NFAT R-HSA-2025928
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
C-type lectin receptors (CLRs) R-HSA-5621481
Beta-catenin independent WNT signaling R-HSA-3858494
DARPP-32 events R-HSA-180024
Signaling by WNT R-HSA-195721
Opioid Signalling R-HSA-111885
FCERI mediated Ca+2 mobilization R-HSA-2871809
Signal Transduction R-HSA-162582
Signaling by the B Cell Receptor (BCR) R-HSA-983705
C-type lectin receptors (CLRs) R-HSA-5621481
Beta-catenin independent WNT signaling R-HSA-3858494
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by GPCR R-HSA-372790
Signaling by WNT R-HSA-195721
DARPP-32 events R-HSA-180024
Immune System R-HSA-168256
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
CLEC7A (Dectin-1) signaling R-HSA-5607764
Calcineurin activates NFAT R-HSA-2025928
Innate Immune System R-HSA-168249
Ca2+ pathway R-HSA-4086398
Adaptive Immune System R-HSA-1280218
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
C-type lectin receptors (CLRs) R-HSA-5621481
Adaptive Immune System R-HSA-1280218
FCERI mediated Ca+2 mobilization R-HSA-2871809
DARPP-32 events R-HSA-180024
Signaling by WNT R-HSA-195721
Ca2+ pathway R-HSA-4086398
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signal Transduction R-HSA-162582
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
CLEC7A (Dectin-1) signaling R-HSA-5607764
Beta-catenin independent WNT signaling R-HSA-3858494
Immune System R-HSA-168256
Signaling by GPCR R-HSA-372790
Calcineurin activates NFAT R-HSA-2025928
Opioid Signalling R-HSA-111885
G alpha (i) signalling events R-HSA-418594
Innate Immune System R-HSA-168249
GPCR downstream signalling R-HSA-388396

Expression Atlas ENSG00000138814
NCBI gene (formerly Entrezgene) 5530
GeneCards 9314
HGNC Symbol HGNC:9314
MIM gene 114105
MIM morbid 618265
UniProtKB Gene Name Q08209
WikiGene 5530
Gene: PTPRB
Ensembl ID : ENSG00000127329
Description: protein tyrosine phosphatase receptor type B
Gene Synonyms: PTPB
1 APIs:
268 Possible Orthologues:

Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249

Expression Atlas ENSG00000127329
NCBI gene (formerly Entrezgene) 5787
GeneCards 9665
HGNC Symbol HGNC:9665
MIM gene 176882
UniProtKB Gene Name Q6ZR19
WikiGene 5787