Gene: MST1R
Ensembl ID : ENSG00000164078
Description: macrophage stimulating 1 receptor
Gene Synonyms: CD136,CDW136,PTK8,RON,SEA
3 APIs:
268 Possible Orthologues:

Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by MST1 R-HSA-8852405
Signal Transduction R-HSA-162582
Signaling by MST1 R-HSA-8852405
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by MST1 R-HSA-8852405
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by MST1 R-HSA-8852405
Signaling by MST1 R-HSA-8852405
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by MST1 R-HSA-8852405
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by MST1 R-HSA-8852405
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by MST1 R-HSA-8852405
Signal Transduction R-HSA-162582
Signaling by MST1 R-HSA-8852405
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by MST1 R-HSA-8852405
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000164078
NCBI gene (formerly Entrezgene) 4486
GeneCards 7381
HGNC Symbol HGNC:7381
MIM gene 600168
MIM morbid 617075
UniProtKB Gene Name Q04912
WikiGene 4486
Gene: IGF1R
Ensembl ID : ENSG00000140443
Description: insulin like growth factor 1 receptor
Gene Synonyms: CD221,IGFIR,IGFR,JTK13,MGC18216
20 APIs:
276 Possible Orthologues:

ESR-mediated signaling R-HSA-8939211
Signaling by Nuclear Receptors R-HSA-9006931
IGF1R signaling cascade R-HSA-2428924
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IRS-related events triggered by IGF1R R-HSA-2428928
Signal Transduction R-HSA-162582
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Extra-nuclear estrogen signaling R-HSA-9009391
SHC-related events triggered by IGF1R R-HSA-2428933
Signal Transduction R-HSA-162582
ESR-mediated signaling R-HSA-8939211
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SHC-related events triggered by IGF1R R-HSA-2428933
Extra-nuclear estrogen signaling R-HSA-9009391
IGF1R signaling cascade R-HSA-2428924
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
IGF1R signaling cascade R-HSA-2428924
SHC-related events triggered by IGF1R R-HSA-2428933
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
ESR-mediated signaling R-HSA-8939211
Extra-nuclear estrogen signaling R-HSA-9009391
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Nuclear Receptors R-HSA-9006931
ESR-mediated signaling R-HSA-8939211
SHC-related events triggered by IGF1R R-HSA-2428933
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
IGF1R signaling cascade R-HSA-2428924
Signal Transduction R-HSA-162582
IRS-related events triggered by IGF1R R-HSA-2428928
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Nuclear Receptors R-HSA-9006931
IRS-related events triggered by IGF1R R-HSA-2428928
ESR-mediated signaling R-HSA-8939211
IGF1R signaling cascade R-HSA-2428924
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
SHC-related events triggered by IGF1R R-HSA-2428933
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Extra-nuclear estrogen signaling R-HSA-9009391
IGF1R signaling cascade R-HSA-2428924
Extra-nuclear estrogen signaling R-HSA-9009391
ESR-mediated signaling R-HSA-8939211
Signaling by Nuclear Receptors R-HSA-9006931
SHC-related events triggered by IGF1R R-HSA-2428933
Signal Transduction R-HSA-162582
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
ESR-mediated signaling R-HSA-8939211
Extra-nuclear estrogen signaling R-HSA-9009391
Signal Transduction R-HSA-162582
IGF1R signaling cascade R-HSA-2428924
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Nuclear Receptors R-HSA-9006931
IRS-related events triggered by IGF1R R-HSA-2428928
SHC-related events triggered by IGF1R R-HSA-2428933
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IRS-related events triggered by IGF1R R-HSA-2428928
SHC-related events triggered by IGF1R R-HSA-2428933
IGF1R signaling cascade R-HSA-2428924
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
ESR-mediated signaling R-HSA-8939211
Extra-nuclear estrogen signaling R-HSA-9009391
Signal Transduction R-HSA-162582
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
IGF1R signaling cascade R-HSA-2428924
SHC-related events triggered by IGF1R R-HSA-2428933
ESR-mediated signaling R-HSA-8939211
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Extra-nuclear estrogen signaling R-HSA-9009391
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Nuclear Receptors R-HSA-9006931
SHC-related events triggered by IGF1R R-HSA-2428933
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
ESR-mediated signaling R-HSA-8939211
Extra-nuclear estrogen signaling R-HSA-9009391
Signal Transduction R-HSA-162582
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
IGF1R signaling cascade R-HSA-2428924
IRS-related events triggered by IGF1R R-HSA-2428928

Expression Atlas ENSG00000140443
LRG display in Ensembl gene LRG_1055
NCBI gene (formerly Entrezgene) 3480
GeneCards 5465
HGNC Symbol HGNC:5465
MIM gene 147370
MIM morbid 270450
UniProtKB Gene Name P08069
WikiGene 3480
Gene: PRKCG
Ensembl ID : ENSG00000126583
Description: protein kinase C gamma
Gene Synonyms: MGC57564,PKCC,PKCG,SCA14
5 APIs:
200 Possible Orthologues:

G alpha (i) signalling events R-HSA-418594
DAG and IP3 signaling R-HSA-1489509
Transmission across Chemical Synapses R-HSA-112315
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
PLC beta mediated events R-HSA-112043
G alpha (z) signalling events R-HSA-418597
Beta-catenin independent WNT signaling R-HSA-3858494
CaM pathway R-HSA-111997
Signaling by WNT R-HSA-195721
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Trafficking of AMPA receptors R-HSA-399719
Intracellular signaling by second messengers R-HSA-9006925
Neuronal System R-HSA-112316
Platelet activation, signaling and aggregation R-HSA-76002
Disinhibition of SNARE formation R-HSA-114516
PCP/CE pathway R-HSA-4086400
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Calmodulin induced events R-HSA-111933
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Opioid Signalling R-HSA-111885
Ca-dependent events R-HSA-111996
Signal Transduction R-HSA-162582
WNT5A-dependent internalization of FZD4 R-HSA-5099900
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
PLC beta mediated events R-HSA-112043
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Opioid Signalling R-HSA-111885
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
GPCR downstream signalling R-HSA-388396
PCP/CE pathway R-HSA-4086400
G-protein mediated events R-HSA-112040
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
G alpha (i) signalling events R-HSA-418594
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (z) signalling events R-HSA-418597
Signaling by WNT R-HSA-195721
Calmodulin induced events R-HSA-111933
Intracellular signaling by second messengers R-HSA-9006925
Ca-dependent events R-HSA-111996
Signal Transduction R-HSA-162582
Trafficking of AMPA receptors R-HSA-399719
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by GPCR R-HSA-372790
CaM pathway R-HSA-111997
Disinhibition of SNARE formation R-HSA-114516
DAG and IP3 signaling R-HSA-1489509
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
G alpha (i) signalling events R-HSA-418594
PCP/CE pathway R-HSA-4086400
PLC beta mediated events R-HSA-112043
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Signaling by WNT R-HSA-195721
Ca-dependent events R-HSA-111996
DAG and IP3 signaling R-HSA-1489509
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
Intracellular signaling by second messengers R-HSA-9006925
WNT5A-dependent internalization of FZD4 R-HSA-5099900
G alpha (z) signalling events R-HSA-418597
Opioid Signalling R-HSA-111885
Beta-catenin independent WNT signaling R-HSA-3858494
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Calmodulin induced events R-HSA-111933
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Disinhibition of SNARE formation R-HSA-114516
CaM pathway R-HSA-111997
Trafficking of AMPA receptors R-HSA-399719
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Neuronal System R-HSA-112316
Beta-catenin independent WNT signaling R-HSA-3858494
DAG and IP3 signaling R-HSA-1489509
Calmodulin induced events R-HSA-111933
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Intracellular signaling by second messengers R-HSA-9006925
Trafficking of AMPA receptors R-HSA-399719
Signal Transduction R-HSA-162582
Ca-dependent events R-HSA-111996
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by WNT R-HSA-195721
G-protein mediated events R-HSA-112040
Signaling by GPCR R-HSA-372790
PCP/CE pathway R-HSA-4086400
PLC beta mediated events R-HSA-112043
G alpha (i) signalling events R-HSA-418594
G alpha (z) signalling events R-HSA-418597
GPCR downstream signalling R-HSA-388396
Opioid Signalling R-HSA-111885
Transmission across Chemical Synapses R-HSA-112315
CaM pathway R-HSA-111997
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Disinhibition of SNARE formation R-HSA-114516
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
DAG and IP3 signaling R-HSA-1489509
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signaling by WNT R-HSA-195721
PLC beta mediated events R-HSA-112043
Intracellular signaling by second messengers R-HSA-9006925
G-protein mediated events R-HSA-112040
PCP/CE pathway R-HSA-4086400
Neuronal System R-HSA-112316
Signal Transduction R-HSA-162582
Ca-dependent events R-HSA-111996
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Calmodulin induced events R-HSA-111933
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Disinhibition of SNARE formation R-HSA-114516
G alpha (z) signalling events R-HSA-418597
CaM pathway R-HSA-111997
Transmission across Chemical Synapses R-HSA-112315
Signaling by GPCR R-HSA-372790
Beta-catenin independent WNT signaling R-HSA-3858494
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Platelet activation, signaling and aggregation R-HSA-76002
Trafficking of AMPA receptors R-HSA-399719
Opioid Signalling R-HSA-111885
Beta-catenin independent WNT signaling R-HSA-3858494
G alpha (i) signalling events R-HSA-418594
Hemostasis R-HSA-109582
WNT5A-dependent internalization of FZD4 R-HSA-5099900
G-protein mediated events R-HSA-112040
Trafficking of AMPA receptors R-HSA-399719
PCP/CE pathway R-HSA-4086400
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Calmodulin induced events R-HSA-111933
GPCR downstream signalling R-HSA-388396
Disinhibition of SNARE formation R-HSA-114516
DAG and IP3 signaling R-HSA-1489509
Transmission across Chemical Synapses R-HSA-112315
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neuronal System R-HSA-112316
Ca-dependent events R-HSA-111996
G alpha (z) signalling events R-HSA-418597
Opioid Signalling R-HSA-111885
PLC beta mediated events R-HSA-112043
Intracellular signaling by second messengers R-HSA-9006925
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Signaling by WNT R-HSA-195721
Platelet activation, signaling and aggregation R-HSA-76002
CaM pathway R-HSA-111997
Signaling by GPCR R-HSA-372790
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signal Transduction R-HSA-162582
Beta-catenin independent WNT signaling R-HSA-3858494
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
GPCR downstream signalling R-HSA-388396
DAG and IP3 signaling R-HSA-1489509
Trafficking of AMPA receptors R-HSA-399719
Ca-dependent events R-HSA-111996
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signaling by GPCR R-HSA-372790
CaM pathway R-HSA-111997
Signaling by WNT R-HSA-195721
Calmodulin induced events R-HSA-111933
PLC beta mediated events R-HSA-112043
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neuronal System R-HSA-112316
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
Platelet activation, signaling and aggregation R-HSA-76002
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Transmission across Chemical Synapses R-HSA-112315
Opioid Signalling R-HSA-111885
Disinhibition of SNARE formation R-HSA-114516
G alpha (z) signalling events R-HSA-418597
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Hemostasis R-HSA-109582
CaM pathway R-HSA-111997
Trafficking of AMPA receptors R-HSA-399719
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Transmission across Chemical Synapses R-HSA-112315
Signaling by WNT R-HSA-195721
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Disinhibition of SNARE formation R-HSA-114516
G alpha (z) signalling events R-HSA-418597
DAG and IP3 signaling R-HSA-1489509
Platelet activation, signaling and aggregation R-HSA-76002
Neuronal System R-HSA-112316
Calmodulin induced events R-HSA-111933
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Opioid Signalling R-HSA-111885
Ca-dependent events R-HSA-111996
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
PLC beta mediated events R-HSA-112043
G-protein mediated events R-HSA-112040
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
CaM pathway R-HSA-111997
PLC beta mediated events R-HSA-112043
Beta-catenin independent WNT signaling R-HSA-3858494
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Opioid Signalling R-HSA-111885
Intracellular signaling by second messengers R-HSA-9006925
Trafficking of AMPA receptors R-HSA-399719
G alpha (i) signalling events R-HSA-418594
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
G-protein mediated events R-HSA-112040
Disinhibition of SNARE formation R-HSA-114516
PCP/CE pathway R-HSA-4086400
Neuronal System R-HSA-112316
Hemostasis R-HSA-109582
GPCR downstream signalling R-HSA-388396
Transmission across Chemical Synapses R-HSA-112315
Signaling by GPCR R-HSA-372790
Ca-dependent events R-HSA-111996
G alpha (z) signalling events R-HSA-418597
DAG and IP3 signaling R-HSA-1489509
Signaling by WNT R-HSA-195721
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Calmodulin induced events R-HSA-111933
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Disinhibition of SNARE formation R-HSA-114516
Opioid Signalling R-HSA-111885
Signal Transduction R-HSA-162582
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Beta-catenin independent WNT signaling R-HSA-3858494
Intracellular signaling by second messengers R-HSA-9006925
Ca-dependent events R-HSA-111996
Calmodulin induced events R-HSA-111933
Signaling by GPCR R-HSA-372790
G-protein mediated events R-HSA-112040
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
DAG and IP3 signaling R-HSA-1489509
Neuronal System R-HSA-112316
G alpha (z) signalling events R-HSA-418597
PCP/CE pathway R-HSA-4086400
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Platelet activation, signaling and aggregation R-HSA-76002
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by WNT R-HSA-195721
CaM pathway R-HSA-111997
G alpha (i) signalling events R-HSA-418594
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
PLC beta mediated events R-HSA-112043
Trafficking of AMPA receptors R-HSA-399719
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Transmission across Chemical Synapses R-HSA-112315

Expression Atlas ENSG00000126583
LRG display in Ensembl gene LRG_669
NCBI gene (formerly Entrezgene) 5582
GeneCards 9402
HGNC Symbol HGNC:9402
MIM gene 176980
MIM morbid 605361
UniProtKB Gene Name P05129
WikiGene 5582
Gene: ITK
Ensembl ID : ENSG00000113263
Description: IL2 inducible T cell kinase
Gene Synonyms: EMT,LYK,PSCTK2
1 APIs:
208 Possible Orthologues:

Adaptive Immune System R-HSA-1280218
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Adaptive Immune System R-HSA-1280218
TCR signaling R-HSA-202403
FCERI mediated Ca+2 mobilization R-HSA-2871809
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Generation of second messenger molecules R-HSA-202433
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Generation of second messenger molecules R-HSA-202433
Adaptive Immune System R-HSA-1280218
FCERI mediated Ca+2 mobilization R-HSA-2871809
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCERI mediated Ca+2 mobilization R-HSA-2871809
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Generation of second messenger molecules R-HSA-202433
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TCR signaling R-HSA-202403
Adaptive Immune System R-HSA-1280218
FCERI mediated Ca+2 mobilization R-HSA-2871809
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Generation of second messenger molecules R-HSA-202433
Generation of second messenger molecules R-HSA-202433
FCERI mediated Ca+2 mobilization R-HSA-2871809
Immune System R-HSA-168256
TCR signaling R-HSA-202403
Adaptive Immune System R-HSA-1280218
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
Generation of second messenger molecules R-HSA-202433
TCR signaling R-HSA-202403
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCERI mediated Ca+2 mobilization R-HSA-2871809
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Generation of second messenger molecules R-HSA-202433
TCR signaling R-HSA-202403
FCERI mediated Ca+2 mobilization R-HSA-2871809
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
FCERI mediated Ca+2 mobilization R-HSA-2871809
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Generation of second messenger molecules R-HSA-202433
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TCR signaling R-HSA-202403
Adaptive Immune System R-HSA-1280218
FCERI mediated Ca+2 mobilization R-HSA-2871809
Immune System R-HSA-168256
Generation of second messenger molecules R-HSA-202433
Generation of second messenger molecules R-HSA-202433
FCERI mediated Ca+2 mobilization R-HSA-2871809
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403

Expression Atlas ENSG00000113263
LRG display in Ensembl gene LRG_189
NCBI gene (formerly Entrezgene) 3702
GeneCards 6171
HGNC Symbol HGNC:6171
MIM gene 186973
MIM morbid 613011
UniProtKB Gene Name Q08881
WikiGene 3702
Gene: MET
Ensembl ID : ENSG00000105976
Description: MET proto-oncogene, receptor tyrosine kinase
Gene Synonyms: DFNB97,HGFR,RCCP2
36 APIs:
207 Possible Orthologues:

Developmental Biology R-HSA-1266738
PIP3 activates AKT signaling R-HSA-1257604
PI3K/AKT Signaling in Cancer R-HSA-2219528
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MET Receptor Activation R-HSA-6806942
MET activates PTPN11 R-HSA-8865999
Transcriptional Regulation by MECP2 R-HSA-8986944
Signaling by MET R-HSA-6806834
Sema4D in semaphorin signaling R-HSA-400685
Nervous system development R-HSA-9675108
MET activates RAP1 and RAC1 R-HSA-8875555
MAPK family signaling cascades R-HSA-5683057
MET activates STAT3 R-HSA-8875791
MET receptor recycling R-HSA-8875656
Signal Transduction R-HSA-162582
MET activates PTK2 signaling R-HSA-8874081
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MET promotes cell motility R-HSA-8875878
Semaphorin interactions R-HSA-373755
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
Drug-mediated inhibition of MET activation R-HSA-9734091
Negative regulation of MET activity R-HSA-6807004
Negative regulation of the PI3K/AKT network R-HSA-199418
MET activates PI3K/AKT signaling R-HSA-8851907
Gene expression (Transcription) R-HSA-74160
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
MET activates RAS signaling R-HSA-8851805
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Listeria monocytogenes entry into host cells R-HSA-8876384
MET interacts with TNS proteins R-HSA-8875513
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RNA Polymerase II Transcription R-HSA-73857
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
MET receptor recycling R-HSA-8875656
Sema4D in semaphorin signaling R-HSA-400685
Negative regulation of MET activity R-HSA-6807004
Transcriptional Regulation by MECP2 R-HSA-8986944
PI3K/AKT Signaling in Cancer R-HSA-2219528
MET activates PTPN11 R-HSA-8865999
Intracellular signaling by second messengers R-HSA-9006925
Nervous system development R-HSA-9675108
Semaphorin interactions R-HSA-373755
MET activates PI3K/AKT signaling R-HSA-8851907
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MET activates PTK2 signaling R-HSA-8874081
Signal Transduction R-HSA-162582
MET activates STAT3 R-HSA-8875791
MET activates RAP1 and RAC1 R-HSA-8875555
Signaling by MET R-HSA-6806834
MET activates RAS signaling R-HSA-8851805
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
MET interacts with TNS proteins R-HSA-8875513
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
Listeria monocytogenes entry into host cells R-HSA-8876384
Gene expression (Transcription) R-HSA-74160
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Generic Transcription Pathway R-HSA-212436
MET Receptor Activation R-HSA-6806942
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
Drug-mediated inhibition of MET activation R-HSA-9734091
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MET promotes cell motility R-HSA-8875878
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
MET receptor recycling R-HSA-8875656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Semaphorin interactions R-HSA-373755
Transcriptional Regulation by MECP2 R-HSA-8986944
MET activates PTPN11 R-HSA-8865999
RAF/MAP kinase cascade R-HSA-5673001
Listeria monocytogenes entry into host cells R-HSA-8876384
Axon guidance R-HSA-422475
MET activates PI3K/AKT signaling R-HSA-8851907
Sema4D in semaphorin signaling R-HSA-400685
MAPK family signaling cascades R-HSA-5683057
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
MET activates RAP1 and RAC1 R-HSA-8875555
Generic Transcription Pathway R-HSA-212436
Intracellular signaling by second messengers R-HSA-9006925
Drug-mediated inhibition of MET activation R-HSA-9734091
MET activates STAT3 R-HSA-8875791
Signaling by MET R-HSA-6806834
RNA Polymerase II Transcription R-HSA-73857
MET activates RAS signaling R-HSA-8851805
Infectious disease R-HSA-5663205
Negative regulation of MET activity R-HSA-6807004
MET activates PTK2 signaling R-HSA-8874081
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Disease R-HSA-1643685
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
MET promotes cell motility R-HSA-8875878
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
MET Receptor Activation R-HSA-6806942
MET interacts with TNS proteins R-HSA-8875513
MAPK1/MAPK3 signaling R-HSA-5684996
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
PI3K/AKT Signaling in Cancer R-HSA-2219528
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by MET R-HSA-6806834
MET activates RAS signaling R-HSA-8851805
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
Disease R-HSA-1643685
MET activates PI3K/AKT signaling R-HSA-8851907
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAF/MAP kinase cascade R-HSA-5673001
Semaphorin interactions R-HSA-373755
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
MET promotes cell motility R-HSA-8875878
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of the PI3K/AKT network R-HSA-199418
Negative regulation of MET activity R-HSA-6807004
Listeria monocytogenes entry into host cells R-HSA-8876384
MET activates PTPN11 R-HSA-8865999
Transcriptional Regulation by MECP2 R-HSA-8986944
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MET activates STAT3 R-HSA-8875791
Nervous system development R-HSA-9675108
MET interacts with TNS proteins R-HSA-8875513
Sema4D in semaphorin signaling R-HSA-400685
Generic Transcription Pathway R-HSA-212436
Intracellular signaling by second messengers R-HSA-9006925
Developmental Biology R-HSA-1266738
MET receptor recycling R-HSA-8875656
MET activates RAP1 and RAC1 R-HSA-8875555
MET Receptor Activation R-HSA-6806942
PI3K/AKT Signaling in Cancer R-HSA-2219528
MET activates PTK2 signaling R-HSA-8874081
Drug-mediated inhibition of MET activation R-HSA-9734091
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
MET activates RAP1 and RAC1 R-HSA-8875555
Drug-mediated inhibition of MET activation R-HSA-9734091
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Sema4D in semaphorin signaling R-HSA-400685
MET activates PTPN11 R-HSA-8865999
Transcriptional Regulation by MECP2 R-HSA-8986944
MET activates STAT3 R-HSA-8875791
Nervous system development R-HSA-9675108
Listeria monocytogenes entry into host cells R-HSA-8876384
Signal Transduction R-HSA-162582
MET activates RAS signaling R-HSA-8851805
MET activates PI3K/AKT signaling R-HSA-8851907
MAPK family signaling cascades R-HSA-5683057
Negative regulation of MET activity R-HSA-6807004
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Intracellular signaling by second messengers R-HSA-9006925
Semaphorin interactions R-HSA-373755
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
Generic Transcription Pathway R-HSA-212436
Signaling by MET R-HSA-6806834
MET receptor recycling R-HSA-8875656
PIP3 activates AKT signaling R-HSA-1257604
MET interacts with TNS proteins R-HSA-8875513
RAF/MAP kinase cascade R-HSA-5673001
MECP2 regulates neuronal receptors and channels R-HSA-9022699
RNA Polymerase II Transcription R-HSA-73857
Infectious disease R-HSA-5663205
MET promotes cell motility R-HSA-8875878
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
MET Receptor Activation R-HSA-6806942
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
PI3K/AKT Signaling in Cancer R-HSA-2219528
MET activates PTK2 signaling R-HSA-8874081
Transcriptional Regulation by MECP2 R-HSA-8986944
MET activates PTK2 signaling R-HSA-8874081
Developmental Biology R-HSA-1266738
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by MET R-HSA-6806834
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Semaphorin interactions R-HSA-373755
Sema4D in semaphorin signaling R-HSA-400685
Negative regulation of MET activity R-HSA-6807004
Generic Transcription Pathway R-HSA-212436
Listeria monocytogenes entry into host cells R-HSA-8876384
Axon guidance R-HSA-422475
Drug-mediated inhibition of MET activation R-HSA-9734091
MAPK1/MAPK3 signaling R-HSA-5684996
Infectious disease R-HSA-5663205
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MET interacts with TNS proteins R-HSA-8875513
MET Receptor Activation R-HSA-6806942
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
RAF/MAP kinase cascade R-HSA-5673001
MET activates RAS signaling R-HSA-8851805
MET activates STAT3 R-HSA-8875791
MAPK family signaling cascades R-HSA-5683057
MET promotes cell motility R-HSA-8875878
MET receptor recycling R-HSA-8875656
MET activates RAP1 and RAC1 R-HSA-8875555
MET activates PI3K/AKT signaling R-HSA-8851907
MET activates PTPN11 R-HSA-8865999
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
Developmental Biology R-HSA-1266738
MET promotes cell motility R-HSA-8875878
Generic Transcription Pathway R-HSA-212436
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
MET activates PI3K/AKT signaling R-HSA-8851907
MET activates RAS signaling R-HSA-8851805
MAPK1/MAPK3 signaling R-HSA-5684996
MET receptor recycling R-HSA-8875656
Signal Transduction R-HSA-162582
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Infectious disease R-HSA-5663205
Intracellular signaling by second messengers R-HSA-9006925
MAPK family signaling cascades R-HSA-5683057
Listeria monocytogenes entry into host cells R-HSA-8876384
Drug-mediated inhibition of MET activation R-HSA-9734091
Disease R-HSA-1643685
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
RNA Polymerase II Transcription R-HSA-73857
Semaphorin interactions R-HSA-373755
Nervous system development R-HSA-9675108
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Sema4D in semaphorin signaling R-HSA-400685
MET activates RAP1 and RAC1 R-HSA-8875555
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
MET activates STAT3 R-HSA-8875791
Transcriptional Regulation by MECP2 R-HSA-8986944
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by MET R-HSA-6806834
Negative regulation of MET activity R-HSA-6807004
MET Receptor Activation R-HSA-6806942
MET activates PTK2 signaling R-HSA-8874081
Axon guidance R-HSA-422475
MET activates PTPN11 R-HSA-8865999
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MET interacts with TNS proteins R-HSA-8875513
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
PI3K/AKT Signaling in Cancer R-HSA-2219528
Gene expression (Transcription) R-HSA-74160
Sema4D in semaphorin signaling R-HSA-400685
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
MET activates RAP1 and RAC1 R-HSA-8875555
Nervous system development R-HSA-9675108
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of the PI3K/AKT network R-HSA-199418
MET activates PTPN11 R-HSA-8865999
PI3K/AKT Signaling in Cancer R-HSA-2219528
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Semaphorin interactions R-HSA-373755
Negative regulation of MET activity R-HSA-6807004
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional Regulation by MECP2 R-HSA-8986944
MET activates STAT3 R-HSA-8875791
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
Signaling by MET R-HSA-6806834
MET receptor recycling R-HSA-8875656
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Drug-mediated inhibition of MET activation R-HSA-9734091
MET activates PTK2 signaling R-HSA-8874081
MET activates RAS signaling R-HSA-8851805
MET promotes cell motility R-HSA-8875878
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
MET Receptor Activation R-HSA-6806942
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MET activates PI3K/AKT signaling R-HSA-8851907
Infectious disease R-HSA-5663205
MET interacts with TNS proteins R-HSA-8875513
Generic Transcription Pathway R-HSA-212436
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Listeria monocytogenes entry into host cells R-HSA-8876384
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by MECP2 R-HSA-8986944
MET promotes cell motility R-HSA-8875878
MET activates PI3K/AKT signaling R-HSA-8851907
MET activates RAP1 and RAC1 R-HSA-8875555
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Negative regulation of MET activity R-HSA-6807004
MET Receptor Activation R-HSA-6806942
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MET activates PTK2 signaling R-HSA-8874081
Listeria monocytogenes entry into host cells R-HSA-8876384
RAF/MAP kinase cascade R-HSA-5673001
MECP2 regulates neuronal receptors and channels R-HSA-9022699
MET receptor recycling R-HSA-8875656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MET activates RAS signaling R-HSA-8851805
MET interacts with TNS proteins R-HSA-8875513
MAPK1/MAPK3 signaling R-HSA-5684996
MET activates STAT3 R-HSA-8875791
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
RNA Polymerase II Transcription R-HSA-73857
Drug-mediated inhibition of MET activation R-HSA-9734091
MAPK family signaling cascades R-HSA-5683057
MET activates PTPN11 R-HSA-8865999
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
Disease R-HSA-1643685
Semaphorin interactions R-HSA-373755
Intracellular signaling by second messengers R-HSA-9006925
Signaling by MET R-HSA-6806834
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of the PI3K/AKT network R-HSA-199418
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Sema4D in semaphorin signaling R-HSA-400685
PI3K/AKT Signaling in Cancer R-HSA-2219528
MET activates PI3K/AKT signaling R-HSA-8851907
PIP3 activates AKT signaling R-HSA-1257604
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360
Signal Transduction R-HSA-162582
MAPK1/MAPK3 signaling R-HSA-5684996
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
MET Receptor Activation R-HSA-6806942
PI3K/AKT Signaling in Cancer R-HSA-2219528
MET activates RAS signaling R-HSA-8851805
Signaling by MET R-HSA-6806834
Intracellular signaling by second messengers R-HSA-9006925
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK family signaling cascades R-HSA-5683057
Sema4D in semaphorin signaling R-HSA-400685
Transcriptional Regulation by MECP2 R-HSA-8986944
Disease R-HSA-1643685
MET receptor recycling R-HSA-8875656
Semaphorin interactions R-HSA-373755
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MET activates PTK2 signaling R-HSA-8874081
MET activates PTPN11 R-HSA-8865999
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RNA Polymerase II Transcription R-HSA-73857
MET activates RAP1 and RAC1 R-HSA-8875555
Negative regulation of MET activity R-HSA-6807004
MET promotes cell motility R-HSA-8875878
Listeria monocytogenes entry into host cells R-HSA-8876384
Drug-mediated inhibition of MET activation R-HSA-9734091
Infectious disease R-HSA-5663205
MECP2 regulates neuronal receptors and channels R-HSA-9022699
MET interacts with TNS proteins R-HSA-8875513
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF/MAP kinase cascade R-HSA-5673001
MET activates STAT3 R-HSA-8875791
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108

Expression Atlas ENSG00000105976
LRG display in Ensembl gene LRG_662
NCBI gene (formerly Entrezgene) 4233
GeneCards 7029
HGNC Symbol HGNC:7029
MIM gene 164860
MIM morbid 620019
UniProtKB Gene Name P08581
WikiGene 4233
Gene: EML4
Ensembl ID : ENSG00000143924
Description: EMAP like 4
Gene Synonyms: C2ORF2,ELP120,ROPP120
5 APIs:
214 Possible Orthologues:

ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK in cancer R-HSA-9700206
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Mitotic Prometaphase R-HSA-68877
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
ALK mutants bind TKIs R-HSA-9700645
Disease R-HSA-1643685
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK fusions and activated point mutants R-HSA-9725370
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Cell Cycle R-HSA-1640170
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
M Phase R-HSA-68886
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Cell Cycle, Mitotic R-HSA-69278
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Mitotic Prometaphase R-HSA-68877
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
ALK mutants bind TKIs R-HSA-9700645
M Phase R-HSA-68886
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK in cancer R-HSA-9700206
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Cell Cycle, Mitotic R-HSA-69278
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
ALK mutants bind TKIs R-HSA-9700645
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Mitotic Prometaphase R-HSA-68877
Cell Cycle, Mitotic R-HSA-69278
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
ALK mutants bind TKIs R-HSA-9700645
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by ALK in cancer R-HSA-9700206
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Signaling by ALK in cancer R-HSA-9700206
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Disease R-HSA-1643685
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Cell Cycle R-HSA-1640170
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
M Phase R-HSA-68886

Expression Atlas ENSG00000143924
NCBI gene (formerly Entrezgene) 27436
GeneCards 1316
HGNC Symbol HGNC:1316
MIM gene 607442
UniProtKB Gene Name Q9HC35
WikiGene 27436
Gene: WEE1
Ensembl ID : ENSG00000166483
Description: WEE1 G2 checkpoint kinase
Gene Synonyms: WEE1A
1 APIs:
227 Possible Orthologues:

Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Polo-like kinase mediated events R-HSA-156711
G1/S Transition R-HSA-69206
G2/M Checkpoints R-HSA-69481
Mitotic G2-G2/M phases R-HSA-453274
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Hemostasis R-HSA-109582
G2/M Transition R-HSA-69275
S Phase R-HSA-69242
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle R-HSA-1640170
G2/M DNA replication checkpoint R-HSA-69478
G2/M DNA damage checkpoint R-HSA-69473
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle Checkpoints R-HSA-69620
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Cell Cycle, Mitotic R-HSA-69278
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
G2/M DNA damage checkpoint R-HSA-69473
Mitotic G1 phase and G1/S transition R-HSA-453279
Hemostasis R-HSA-109582
Polo-like kinase mediated events R-HSA-156711
Mitotic G2-G2/M phases R-HSA-453274
S Phase R-HSA-69242
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G2/M Transition R-HSA-69275
G1/S Transition R-HSA-69206
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
G2/M DNA replication checkpoint R-HSA-69478
G2/M Checkpoints R-HSA-69481
Cell Cycle R-HSA-1640170
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Cell Cycle Checkpoints R-HSA-69620
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Cell Cycle, Mitotic R-HSA-69278
S Phase R-HSA-69242
Cell Cycle Checkpoints R-HSA-69620
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
G2/M Transition R-HSA-69275
Hemostasis R-HSA-109582
Factors involved in megakaryocyte development and platelet production R-HSA-983231
G2/M DNA damage checkpoint R-HSA-69473
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S Transition R-HSA-69206
Polo-like kinase mediated events R-HSA-156711
Cell Cycle, Mitotic R-HSA-69278
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Mitotic G2-G2/M phases R-HSA-453274
G2/M Checkpoints R-HSA-69481
G2/M DNA replication checkpoint R-HSA-69478
G2/M DNA damage checkpoint R-HSA-69473
Hemostasis R-HSA-109582
Cell Cycle Checkpoints R-HSA-69620
Mitotic G1 phase and G1/S transition R-HSA-453279
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
G1/S Transition R-HSA-69206
Cell Cycle, Mitotic R-HSA-69278
S Phase R-HSA-69242
G2/M Checkpoints R-HSA-69481
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic G2-G2/M phases R-HSA-453274
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Cell Cycle R-HSA-1640170
G2/M DNA replication checkpoint R-HSA-69478
Polo-like kinase mediated events R-HSA-156711
G2/M Transition R-HSA-69275
Hemostasis R-HSA-109582
G2/M DNA damage checkpoint R-HSA-69473
Cell Cycle Checkpoints R-HSA-69620
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Polo-like kinase mediated events R-HSA-156711
G2/M DNA replication checkpoint R-HSA-69478
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Cell Cycle, Mitotic R-HSA-69278
G2/M Checkpoints R-HSA-69481
Cell Cycle R-HSA-1640170
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
G2/M Transition R-HSA-69275
G1/S Transition R-HSA-69206
S Phase R-HSA-69242
G2/M DNA replication checkpoint R-HSA-69478
Cyclin E associated events during G1/S transition R-HSA-69202
Polo-like kinase mediated events R-HSA-156711
G1/S Transition R-HSA-69206
G2/M DNA damage checkpoint R-HSA-69473
Factors involved in megakaryocyte development and platelet production R-HSA-983231
S Phase R-HSA-69242
Hemostasis R-HSA-109582
G2/M Checkpoints R-HSA-69481
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle Checkpoints R-HSA-69620
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle R-HSA-1640170
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
G2/M Transition R-HSA-69275
Cell Cycle R-HSA-1640170
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Cell Cycle, Mitotic R-HSA-69278
G1/S Transition R-HSA-69206
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle Checkpoints R-HSA-69620
G2/M DNA replication checkpoint R-HSA-69478
G2/M Checkpoints R-HSA-69481
G2/M DNA damage checkpoint R-HSA-69473
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Factors involved in megakaryocyte development and platelet production R-HSA-983231
S Phase R-HSA-69242
Cyclin E associated events during G1/S transition R-HSA-69202
Polo-like kinase mediated events R-HSA-156711
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hemostasis R-HSA-109582
S Phase R-HSA-69242
G2/M DNA damage checkpoint R-HSA-69473
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Mitotic G2-G2/M phases R-HSA-453274
Mitotic G1 phase and G1/S transition R-HSA-453279
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Cell Cycle R-HSA-1640170
Factors involved in megakaryocyte development and platelet production R-HSA-983231
G2/M DNA replication checkpoint R-HSA-69478
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle Checkpoints R-HSA-69620
G2/M Transition R-HSA-69275
G1/S Transition R-HSA-69206
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G2/M Checkpoints R-HSA-69481
Polo-like kinase mediated events R-HSA-156711
Hemostasis R-HSA-109582
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Cyclin E associated events during G1/S transition R-HSA-69202
S Phase R-HSA-69242
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M DNA replication checkpoint R-HSA-69478
Polo-like kinase mediated events R-HSA-156711
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Cell Cycle, Mitotic R-HSA-69278
Mitotic G2-G2/M phases R-HSA-453274
G1/S Transition R-HSA-69206
Factors involved in megakaryocyte development and platelet production R-HSA-983231
G2/M DNA damage checkpoint R-HSA-69473
G2/M Transition R-HSA-69275
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle R-HSA-1640170
Hemostasis R-HSA-109582
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G2/M Checkpoints R-HSA-69481
G2/M Transition R-HSA-69275
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
G1/S Transition R-HSA-69206
G2/M Checkpoints R-HSA-69481
Polo-like kinase mediated events R-HSA-156711
G2/M DNA replication checkpoint R-HSA-69478
S Phase R-HSA-69242
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Hemostasis R-HSA-109582
Cell Cycle, Mitotic R-HSA-69278
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Cell Cycle Checkpoints R-HSA-69620
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic G2-G2/M phases R-HSA-453274
G2/M DNA damage checkpoint R-HSA-69473

Expression Atlas ENSG00000166483
NCBI gene (formerly Entrezgene) 7465
GeneCards 12761
HGNC Symbol HGNC:12761
MIM gene 193525
UniProtKB Gene Name P30291
WikiGene 7465
Gene: CDK4
Ensembl ID : ENSG00000135446
Description: cyclin dependent kinase 4
Gene Synonyms: PSK-J3
15 APIs:
227 Possible Orthologues:

Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Developmental Biology R-HSA-1266738
PTK6 Regulates Cell Cycle R-HSA-8849470
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RMTs methylate histone arginines R-HSA-3214858
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Meiotic recombination R-HSA-912446
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stimuli R-HSA-8953897
G1/S Transition R-HSA-69206
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Transcriptional regulation of granulopoiesis R-HSA-9616222
Chromatin modifying enzymes R-HSA-3247509
Cell Cycle R-HSA-1640170
Cyclin E associated events during G1/S transition R-HSA-69202
Signal Transduction R-HSA-162582
G1 Phase R-HSA-69236
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Diseases of cellular response to stress R-HSA-9675132
Cellular responses to stress R-HSA-2262752
Oncogene Induced Senescence R-HSA-2559585
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Reproduction R-HSA-1474165
Diseases of mitotic cell cycle R-HSA-9675126
S Phase R-HSA-69242
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
RNA Polymerase II Transcription R-HSA-73857
Chromatin organization R-HSA-4839726
Diseases of Cellular Senescence R-HSA-9630747
Cyclin D associated events in G1 R-HSA-69231
Signaling by PTK6 R-HSA-8848021
Meiosis R-HSA-1500620
Oxidative Stress Induced Senescence R-HSA-2559580
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Cellular Senescence R-HSA-2559583
Generic Transcription Pathway R-HSA-212436
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Gene expression (Transcription) R-HSA-74160
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX2 R-HSA-8878166
Diseases of mitotic cell cycle R-HSA-9675126
Signal Transduction R-HSA-162582
Cyclin E associated events during G1/S transition R-HSA-69202
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
G1 Phase R-HSA-69236
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cellular responses to stimuli R-HSA-8953897
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Cell Cycle, Mitotic R-HSA-69278
Signaling by PTK6 R-HSA-8848021
Cell Cycle R-HSA-1640170
Oxidative Stress Induced Senescence R-HSA-2559580
G1/S Transition R-HSA-69206
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cyclin D associated events in G1 R-HSA-69231
Cellular Senescence R-HSA-2559583
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
PTK6 Regulates Cell Cycle R-HSA-8849470
Meiotic recombination R-HSA-912446
Transcriptional regulation of granulopoiesis R-HSA-9616222
Meiosis R-HSA-1500620
Mitotic G1 phase and G1/S transition R-HSA-453279
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
RMTs methylate histone arginines R-HSA-3214858
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Gene expression (Transcription) R-HSA-74160
Oncogene Induced Senescence R-HSA-2559585
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Disease R-HSA-1643685
S Phase R-HSA-69242
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Chromatin modifying enzymes R-HSA-3247509
Diseases of Cellular Senescence R-HSA-9630747
Chromatin organization R-HSA-4839726
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RNA Polymerase II Transcription R-HSA-73857
Reproduction R-HSA-1474165
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Diseases of cellular response to stress R-HSA-9675132
Oxidative Stress Induced Senescence R-HSA-2559580
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Diseases of mitotic cell cycle R-HSA-9675126
Mitotic G1 phase and G1/S transition R-HSA-453279
Generic Transcription Pathway R-HSA-212436
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Disease R-HSA-1643685
Chromatin modifying enzymes R-HSA-3247509
Cyclin E associated events during G1/S transition R-HSA-69202
PTK6 Regulates Cell Cycle R-HSA-8849470
G1/S Transition R-HSA-69206
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cellular Senescence R-HSA-2559583
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Chromatin organization R-HSA-4839726
Signal Transduction R-HSA-162582
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Diseases of cellular response to stress R-HSA-9675132
RMTs methylate histone arginines R-HSA-3214858
G1 Phase R-HSA-69236
Meiosis R-HSA-1500620
RNA Polymerase II Transcription R-HSA-73857
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Gene expression (Transcription) R-HSA-74160
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Signaling by PTK6 R-HSA-8848021
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Meiotic recombination R-HSA-912446
Reproduction R-HSA-1474165
Cyclin D associated events in G1 R-HSA-69231
Cell Cycle R-HSA-1640170
Transcriptional regulation of granulopoiesis R-HSA-9616222
Oncogene Induced Senescence R-HSA-2559585
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Diseases of Cellular Senescence R-HSA-9630747
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
S Phase R-HSA-69242
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Reproduction R-HSA-1474165
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Gene expression (Transcription) R-HSA-74160
Diseases of mitotic cell cycle R-HSA-9675126
Mitotic G1 phase and G1/S transition R-HSA-453279
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
PTK6 Regulates Cell Cycle R-HSA-8849470
Signal Transduction R-HSA-162582
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Disease R-HSA-1643685
Oncogene Induced Senescence R-HSA-2559585
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Diseases of cellular response to stress R-HSA-9675132
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of Cellular Senescence R-HSA-9630747
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Chromatin organization R-HSA-4839726
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cyclin D associated events in G1 R-HSA-69231
Meiosis R-HSA-1500620
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Transcriptional regulation of granulopoiesis R-HSA-9616222
RNA Polymerase II Transcription R-HSA-73857
Meiotic recombination R-HSA-912446
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stimuli R-HSA-8953897
G1/S Transition R-HSA-69206
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
S Phase R-HSA-69242
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
RMTs methylate histone arginines R-HSA-3214858
Cell Cycle R-HSA-1640170
G1 Phase R-HSA-69236
Cellular Senescence R-HSA-2559583
Chromatin modifying enzymes R-HSA-3247509
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle, Mitotic R-HSA-69278
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Signaling by PTK6 R-HSA-8848021
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Cyclin E associated events during G1/S transition R-HSA-69202
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
Reproduction R-HSA-1474165
Cyclin D associated events in G1 R-HSA-69231
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Meiotic recombination R-HSA-912446
Diseases of cellular response to stress R-HSA-9675132
Transcriptional regulation of granulopoiesis R-HSA-9616222
Cellular responses to stress R-HSA-2262752
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Oncogene Induced Senescence R-HSA-2559585
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Cell Cycle R-HSA-1640170
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of Cellular Senescence R-HSA-9630747
Chromatin modifying enzymes R-HSA-3247509
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular Senescence R-HSA-2559583
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G1 Phase R-HSA-69236
RMTs methylate histone arginines R-HSA-3214858
Signal Transduction R-HSA-162582
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
PTK6 Regulates Cell Cycle R-HSA-8849470
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S Transition R-HSA-69206
Diseases of mitotic cell cycle R-HSA-9675126
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Signaling by PTK6 R-HSA-8848021
Meiosis R-HSA-1500620
Cellular responses to stimuli R-HSA-8953897
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Chromatin organization R-HSA-4839726
Oxidative Stress Induced Senescence R-HSA-2559580
Gene expression (Transcription) R-HSA-74160
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Cyclin E associated events during G1/S transition R-HSA-69202
G1/S Transition R-HSA-69206
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cellular Senescence R-HSA-2559583
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Reproduction R-HSA-1474165
Generic Transcription Pathway R-HSA-212436
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Meiosis R-HSA-1500620
Cell Cycle R-HSA-1640170
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Chromatin organization R-HSA-4839726
Cellular responses to stimuli R-HSA-8953897
G1 Phase R-HSA-69236
Diseases of mitotic cell cycle R-HSA-9675126
Diseases of cellular response to stress R-HSA-9675132
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Developmental Biology R-HSA-1266738
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Diseases of Cellular Senescence R-HSA-9630747
Cellular responses to stress R-HSA-2262752
Signaling by PTK6 R-HSA-8848021
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX2 R-HSA-8878166
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Oncogene Induced Senescence R-HSA-2559585
Transcriptional regulation of granulopoiesis R-HSA-9616222
Meiotic recombination R-HSA-912446
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Disease R-HSA-1643685
Chromatin modifying enzymes R-HSA-3247509
Oxidative Stress Induced Senescence R-HSA-2559580
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Cyclin D associated events in G1 R-HSA-69231
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
S Phase R-HSA-69242
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PTK6 Regulates Cell Cycle R-HSA-8849470
RNA Polymerase II Transcription R-HSA-73857
RMTs methylate histone arginines R-HSA-3214858
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S Transition R-HSA-69206
Oncogene Induced Senescence R-HSA-2559585
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Gene expression (Transcription) R-HSA-74160
Mitotic G1 phase and G1/S transition R-HSA-453279
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
RMTs methylate histone arginines R-HSA-3214858
Reproduction R-HSA-1474165
Signal Transduction R-HSA-162582
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Cellular responses to stress R-HSA-2262752
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin D associated events in G1 R-HSA-69231
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Chromatin organization R-HSA-4839726
PTK6 Regulates Cell Cycle R-HSA-8849470
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Diseases of cellular response to stress R-HSA-9675132
Developmental Biology R-HSA-1266738
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Cellular Senescence R-HSA-2559583
Meiotic recombination R-HSA-912446
Cellular responses to stimuli R-HSA-8953897
Chromatin modifying enzymes R-HSA-3247509
Transcriptional regulation of granulopoiesis R-HSA-9616222
Meiosis R-HSA-1500620
Diseases of mitotic cell cycle R-HSA-9675126
Diseases of Cellular Senescence R-HSA-9630747
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
S Phase R-HSA-69242
Signaling by PTK6 R-HSA-8848021
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G1 Phase R-HSA-69236
Oxidative Stress Induced Senescence R-HSA-2559580
Oxidative Stress Induced Senescence R-HSA-2559580
Diseases of cellular response to stress R-HSA-9675132
Cell Cycle, Mitotic R-HSA-69278
Meiosis R-HSA-1500620
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Diseases of Cellular Senescence R-HSA-9630747
S Phase R-HSA-69242
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by PTK6 R-HSA-8848021
G1/S Transition R-HSA-69206
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Cellular Senescence R-HSA-2559583
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Mitotic G1 phase and G1/S transition R-HSA-453279
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Cell Cycle R-HSA-1640170
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
Oncogene Induced Senescence R-HSA-2559585
Transcriptional regulation of granulopoiesis R-HSA-9616222
Chromatin organization R-HSA-4839726
Cyclin E associated events during G1/S transition R-HSA-69202
G1 Phase R-HSA-69236
Reproduction R-HSA-1474165
PTK6 Regulates Cell Cycle R-HSA-8849470
Chromatin modifying enzymes R-HSA-3247509
Meiotic recombination R-HSA-912446
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Cyclin D associated events in G1 R-HSA-69231
Developmental Biology R-HSA-1266738
RMTs methylate histone arginines R-HSA-3214858
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX2 R-HSA-8878166
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cellular responses to stimuli R-HSA-8953897
Diseases of mitotic cell cycle R-HSA-9675126
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Gene expression (Transcription) R-HSA-74160
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Signaling by PTK6 R-HSA-8848021
Developmental Biology R-HSA-1266738
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
PTK6 Regulates Cell Cycle R-HSA-8849470
Cyclin E associated events during G1/S transition R-HSA-69202
Meiotic recombination R-HSA-912446
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle, Mitotic R-HSA-69278
Oxidative Stress Induced Senescence R-HSA-2559580
Chromatin modifying enzymes R-HSA-3247509
Reproduction R-HSA-1474165
Diseases of Cellular Senescence R-HSA-9630747
S Phase R-HSA-69242
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
G1 Phase R-HSA-69236
Cellular responses to stimuli R-HSA-8953897
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Transcriptional regulation of granulopoiesis R-HSA-9616222
RNA Polymerase II Transcription R-HSA-73857
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Cellular Senescence R-HSA-2559583
Diseases of mitotic cell cycle R-HSA-9675126
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cell Cycle R-HSA-1640170
Cellular responses to stress R-HSA-2262752
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Meiosis R-HSA-1500620
RMTs methylate histone arginines R-HSA-3214858
Chromatin organization R-HSA-4839726
Signal Transduction R-HSA-162582
Oncogene Induced Senescence R-HSA-2559585
Diseases of cellular response to stress R-HSA-9675132
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
G1/S Transition R-HSA-69206
Cyclin D associated events in G1 R-HSA-69231
Transcriptional regulation by RUNX2 R-HSA-8878166
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cell Cycle R-HSA-1640170
Meiosis R-HSA-1500620
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Diseases of Cellular Senescence R-HSA-9630747
Cell Cycle, Mitotic R-HSA-69278
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cyclin D associated events in G1 R-HSA-69231
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Oncogene Induced Senescence R-HSA-2559585
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
RNA Polymerase II Transcription R-HSA-73857
RMTs methylate histone arginines R-HSA-3214858
PTK6 Regulates Cell Cycle R-HSA-8849470
G1 Phase R-HSA-69236
Gene expression (Transcription) R-HSA-74160
Chromatin organization R-HSA-4839726
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
S Phase R-HSA-69242
Meiotic recombination R-HSA-912446
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S Transition R-HSA-69206
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Transcriptional regulation of granulopoiesis R-HSA-9616222
Chromatin modifying enzymes R-HSA-3247509
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Reproduction R-HSA-1474165
Developmental Biology R-HSA-1266738
Signaling by PTK6 R-HSA-8848021
Cellular Senescence R-HSA-2559583
Diseases of cellular response to stress R-HSA-9675132
Cellular responses to stress R-HSA-2262752
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Signal Transduction R-HSA-162582
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Mitotic G1 phase and G1/S transition R-HSA-453279
Oxidative Stress Induced Senescence R-HSA-2559580
Generic Transcription Pathway R-HSA-212436
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stimuli R-HSA-8953897
Diseases of mitotic cell cycle R-HSA-9675126
Disease R-HSA-1643685

Expression Atlas ENSG00000135446
LRG display in Ensembl gene LRG_490
NCBI gene (formerly Entrezgene) 1019
GeneCards 1773
HGNC Symbol HGNC:1773
MIM gene 123829
MIM morbid 609048
UniProtKB Gene Name Q96BE9
WikiGene 1019