Gene: MAPK9
Ensembl ID : ENSG00000050748
Description: mitogen-activated protein kinase 9
Gene Synonyms: JNK2,P54A,PRKM9,SAPK
3 APIs:
219 Possible Orthologues:

Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Activation of the AP-1 family of transcription factors R-HSA-450341
MyD88-independent TLR4 cascade R-HSA-166166
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Immune System R-HSA-168256
Oxidative Stress Induced Senescence R-HSA-2559580
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-17 signaling R-HSA-448424
MyD88 cascade initiated on plasma membrane R-HSA-975871
Innate Immune System R-HSA-168249
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Interleukins R-HSA-449147
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular Senescence R-HSA-2559583
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
FCERI mediated MAPK activation R-HSA-2871796
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll-like Receptor Cascades R-HSA-168898
MAP kinase activation R-HSA-450294
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
FCERI mediated MAPK activation R-HSA-2871796
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MAP kinase activation R-HSA-450294
Toll-like Receptor Cascades R-HSA-168898
Cytokine Signaling in Immune system R-HSA-1280215
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Activation of the AP-1 family of transcription factors R-HSA-450341
MyD88 dependent cascade initiated on endosome R-HSA-975155
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stress R-HSA-2262752
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-17 signaling R-HSA-448424
Cellular responses to stimuli R-HSA-8953897
Cellular Senescence R-HSA-2559583
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cellular responses to stress R-HSA-2262752
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88 dependent cascade initiated on endosome R-HSA-975155
MyD88-independent TLR4 cascade R-HSA-166166
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Interleukin-17 signaling R-HSA-448424
Cellular Senescence R-HSA-2559583
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cytokine Signaling in Immune system R-HSA-1280215
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stimuli R-HSA-8953897
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll-like Receptor Cascades R-HSA-168898
Innate Immune System R-HSA-168249
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MAP kinase activation R-HSA-450294
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Activation of the AP-1 family of transcription factors R-HSA-450341
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cytokine Signaling in Immune system R-HSA-1280215
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Interleukin-17 signaling R-HSA-448424
Oxidative Stress Induced Senescence R-HSA-2559580
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88 dependent cascade initiated on endosome R-HSA-975155
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
FCERI mediated MAPK activation R-HSA-2871796
Activation of the AP-1 family of transcription factors R-HSA-450341
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stimuli R-HSA-8953897
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll-like Receptor Cascades R-HSA-168898
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MAP kinase activation R-HSA-450294
Signaling by Interleukins R-HSA-449147
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stress R-HSA-2262752
MAP kinase activation R-HSA-450294
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cellular Senescence R-HSA-2559583
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Immune System R-HSA-168256
Activation of the AP-1 family of transcription factors R-HSA-450341
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88 cascade initiated on plasma membrane R-HSA-975871
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Interleukin-17 signaling R-HSA-448424
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Interleukins R-HSA-449147
Cellular responses to stimuli R-HSA-8953897
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cytokine Signaling in Immune system R-HSA-1280215
MyD88-independent TLR4 cascade R-HSA-166166
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
FCERI mediated MAPK activation R-HSA-2871796
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Interleukin-17 signaling R-HSA-448424
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll-like Receptor Cascades R-HSA-168898
MyD88 dependent cascade initiated on endosome R-HSA-975155
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cytokine Signaling in Immune system R-HSA-1280215
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MAP kinase activation R-HSA-450294
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88-independent TLR4 cascade R-HSA-166166
Cellular Senescence R-HSA-2559583
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cellular responses to stress R-HSA-2262752
MAP kinase activation R-HSA-450294
MyD88 cascade initiated on plasma membrane R-HSA-975871
Activation of the AP-1 family of transcription factors R-HSA-450341
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Immune System R-HSA-168256
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88 dependent cascade initiated on endosome R-HSA-975155
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Interleukin-17 signaling R-HSA-448424
Cellular responses to stimuli R-HSA-8953897
FCERI mediated MAPK activation R-HSA-2871796
Signaling by Interleukins R-HSA-449147
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88-independent TLR4 cascade R-HSA-166166
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Innate Immune System R-HSA-168249
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Activation of the AP-1 family of transcription factors R-HSA-450341
Interleukin-17 signaling R-HSA-448424
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stress R-HSA-2262752
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
FCERI mediated MAPK activation R-HSA-2871796
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88-independent TLR4 cascade R-HSA-166166
Immune System R-HSA-168256
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by Interleukins R-HSA-449147
Oxidative Stress Induced Senescence R-HSA-2559580
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular Senescence R-HSA-2559583
MAP kinase activation R-HSA-450294
Toll-like Receptor Cascades R-HSA-168898
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular responses to stimuli R-HSA-8953897
Innate Immune System R-HSA-168249
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Innate Immune System R-HSA-168249
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Immune System R-HSA-168256
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
FCERI mediated MAPK activation R-HSA-2871796
Cytokine Signaling in Immune system R-HSA-1280215
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular Senescence R-HSA-2559583
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stress R-HSA-2262752
Signaling by Interleukins R-HSA-449147
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular responses to stimuli R-HSA-8953897
MyD88 cascade initiated on plasma membrane R-HSA-975871
Activation of the AP-1 family of transcription factors R-HSA-450341
MAP kinase activation R-HSA-450294
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88-independent TLR4 cascade R-HSA-166166
Toll-like Receptor Cascades R-HSA-168898

Expression Atlas ENSG00000050748
NCBI gene (formerly Entrezgene) 5601
GeneCards 6886
HGNC Symbol HGNC:6886
MIM gene 602896
UniProtKB Gene Name P45984
WikiGene 5601
Gene: PRKCG
Ensembl ID : ENSG00000126583
Description: protein kinase C gamma
Gene Synonyms: MGC57564,PKCC,PKCG,SCA14
5 APIs:
200 Possible Orthologues:

G alpha (i) signalling events R-HSA-418594
DAG and IP3 signaling R-HSA-1489509
Transmission across Chemical Synapses R-HSA-112315
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
PLC beta mediated events R-HSA-112043
G alpha (z) signalling events R-HSA-418597
Beta-catenin independent WNT signaling R-HSA-3858494
CaM pathway R-HSA-111997
Signaling by WNT R-HSA-195721
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Trafficking of AMPA receptors R-HSA-399719
Intracellular signaling by second messengers R-HSA-9006925
Neuronal System R-HSA-112316
Platelet activation, signaling and aggregation R-HSA-76002
Disinhibition of SNARE formation R-HSA-114516
PCP/CE pathway R-HSA-4086400
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Calmodulin induced events R-HSA-111933
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Opioid Signalling R-HSA-111885
Ca-dependent events R-HSA-111996
Signal Transduction R-HSA-162582
WNT5A-dependent internalization of FZD4 R-HSA-5099900
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
PLC beta mediated events R-HSA-112043
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Opioid Signalling R-HSA-111885
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
GPCR downstream signalling R-HSA-388396
PCP/CE pathway R-HSA-4086400
G-protein mediated events R-HSA-112040
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
G alpha (i) signalling events R-HSA-418594
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (z) signalling events R-HSA-418597
Signaling by WNT R-HSA-195721
Calmodulin induced events R-HSA-111933
Intracellular signaling by second messengers R-HSA-9006925
Ca-dependent events R-HSA-111996
Signal Transduction R-HSA-162582
Trafficking of AMPA receptors R-HSA-399719
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by GPCR R-HSA-372790
CaM pathway R-HSA-111997
Disinhibition of SNARE formation R-HSA-114516
DAG and IP3 signaling R-HSA-1489509
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
G alpha (i) signalling events R-HSA-418594
PCP/CE pathway R-HSA-4086400
PLC beta mediated events R-HSA-112043
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Signaling by WNT R-HSA-195721
Ca-dependent events R-HSA-111996
DAG and IP3 signaling R-HSA-1489509
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
Intracellular signaling by second messengers R-HSA-9006925
WNT5A-dependent internalization of FZD4 R-HSA-5099900
G alpha (z) signalling events R-HSA-418597
Opioid Signalling R-HSA-111885
Beta-catenin independent WNT signaling R-HSA-3858494
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Calmodulin induced events R-HSA-111933
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Disinhibition of SNARE formation R-HSA-114516
CaM pathway R-HSA-111997
Trafficking of AMPA receptors R-HSA-399719
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Neuronal System R-HSA-112316
Beta-catenin independent WNT signaling R-HSA-3858494
DAG and IP3 signaling R-HSA-1489509
Calmodulin induced events R-HSA-111933
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Intracellular signaling by second messengers R-HSA-9006925
Trafficking of AMPA receptors R-HSA-399719
Signal Transduction R-HSA-162582
Ca-dependent events R-HSA-111996
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by WNT R-HSA-195721
G-protein mediated events R-HSA-112040
Signaling by GPCR R-HSA-372790
PCP/CE pathway R-HSA-4086400
PLC beta mediated events R-HSA-112043
G alpha (i) signalling events R-HSA-418594
G alpha (z) signalling events R-HSA-418597
GPCR downstream signalling R-HSA-388396
Opioid Signalling R-HSA-111885
Transmission across Chemical Synapses R-HSA-112315
CaM pathway R-HSA-111997
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Disinhibition of SNARE formation R-HSA-114516
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
DAG and IP3 signaling R-HSA-1489509
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signaling by WNT R-HSA-195721
PLC beta mediated events R-HSA-112043
Intracellular signaling by second messengers R-HSA-9006925
G-protein mediated events R-HSA-112040
PCP/CE pathway R-HSA-4086400
Neuronal System R-HSA-112316
Signal Transduction R-HSA-162582
Ca-dependent events R-HSA-111996
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Calmodulin induced events R-HSA-111933
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Disinhibition of SNARE formation R-HSA-114516
G alpha (z) signalling events R-HSA-418597
CaM pathway R-HSA-111997
Transmission across Chemical Synapses R-HSA-112315
Signaling by GPCR R-HSA-372790
Beta-catenin independent WNT signaling R-HSA-3858494
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Platelet activation, signaling and aggregation R-HSA-76002
Trafficking of AMPA receptors R-HSA-399719
Opioid Signalling R-HSA-111885
Beta-catenin independent WNT signaling R-HSA-3858494
G alpha (i) signalling events R-HSA-418594
Hemostasis R-HSA-109582
WNT5A-dependent internalization of FZD4 R-HSA-5099900
G-protein mediated events R-HSA-112040
Trafficking of AMPA receptors R-HSA-399719
PCP/CE pathway R-HSA-4086400
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Calmodulin induced events R-HSA-111933
GPCR downstream signalling R-HSA-388396
Disinhibition of SNARE formation R-HSA-114516
DAG and IP3 signaling R-HSA-1489509
Transmission across Chemical Synapses R-HSA-112315
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neuronal System R-HSA-112316
Ca-dependent events R-HSA-111996
G alpha (z) signalling events R-HSA-418597
Opioid Signalling R-HSA-111885
PLC beta mediated events R-HSA-112043
Intracellular signaling by second messengers R-HSA-9006925
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Signaling by WNT R-HSA-195721
Platelet activation, signaling and aggregation R-HSA-76002
CaM pathway R-HSA-111997
Signaling by GPCR R-HSA-372790
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signal Transduction R-HSA-162582
Beta-catenin independent WNT signaling R-HSA-3858494
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
GPCR downstream signalling R-HSA-388396
DAG and IP3 signaling R-HSA-1489509
Trafficking of AMPA receptors R-HSA-399719
Ca-dependent events R-HSA-111996
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signaling by GPCR R-HSA-372790
CaM pathway R-HSA-111997
Signaling by WNT R-HSA-195721
Calmodulin induced events R-HSA-111933
PLC beta mediated events R-HSA-112043
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neuronal System R-HSA-112316
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
Platelet activation, signaling and aggregation R-HSA-76002
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Transmission across Chemical Synapses R-HSA-112315
Opioid Signalling R-HSA-111885
Disinhibition of SNARE formation R-HSA-114516
G alpha (z) signalling events R-HSA-418597
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Hemostasis R-HSA-109582
CaM pathway R-HSA-111997
Trafficking of AMPA receptors R-HSA-399719
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Transmission across Chemical Synapses R-HSA-112315
Signaling by WNT R-HSA-195721
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Disinhibition of SNARE formation R-HSA-114516
G alpha (z) signalling events R-HSA-418597
DAG and IP3 signaling R-HSA-1489509
Platelet activation, signaling and aggregation R-HSA-76002
Neuronal System R-HSA-112316
Calmodulin induced events R-HSA-111933
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Opioid Signalling R-HSA-111885
Ca-dependent events R-HSA-111996
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
PLC beta mediated events R-HSA-112043
G-protein mediated events R-HSA-112040
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
CaM pathway R-HSA-111997
PLC beta mediated events R-HSA-112043
Beta-catenin independent WNT signaling R-HSA-3858494
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Opioid Signalling R-HSA-111885
Intracellular signaling by second messengers R-HSA-9006925
Trafficking of AMPA receptors R-HSA-399719
G alpha (i) signalling events R-HSA-418594
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
G-protein mediated events R-HSA-112040
Disinhibition of SNARE formation R-HSA-114516
PCP/CE pathway R-HSA-4086400
Neuronal System R-HSA-112316
Hemostasis R-HSA-109582
GPCR downstream signalling R-HSA-388396
Transmission across Chemical Synapses R-HSA-112315
Signaling by GPCR R-HSA-372790
Ca-dependent events R-HSA-111996
G alpha (z) signalling events R-HSA-418597
DAG and IP3 signaling R-HSA-1489509
Signaling by WNT R-HSA-195721
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Calmodulin induced events R-HSA-111933
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Disinhibition of SNARE formation R-HSA-114516
Opioid Signalling R-HSA-111885
Signal Transduction R-HSA-162582
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Beta-catenin independent WNT signaling R-HSA-3858494
Intracellular signaling by second messengers R-HSA-9006925
Ca-dependent events R-HSA-111996
Calmodulin induced events R-HSA-111933
Signaling by GPCR R-HSA-372790
G-protein mediated events R-HSA-112040
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
DAG and IP3 signaling R-HSA-1489509
Neuronal System R-HSA-112316
G alpha (z) signalling events R-HSA-418597
PCP/CE pathway R-HSA-4086400
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Platelet activation, signaling and aggregation R-HSA-76002
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by WNT R-HSA-195721
CaM pathway R-HSA-111997
G alpha (i) signalling events R-HSA-418594
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
PLC beta mediated events R-HSA-112043
Trafficking of AMPA receptors R-HSA-399719
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Transmission across Chemical Synapses R-HSA-112315

Expression Atlas ENSG00000126583
LRG display in Ensembl gene LRG_669
NCBI gene (formerly Entrezgene) 5582
GeneCards 9402
HGNC Symbol HGNC:9402
MIM gene 176980
MIM morbid 605361
UniProtKB Gene Name P05129
WikiGene 5582
Gene: EGFR
Ensembl ID : ENSG00000146648
Description: epidermal growth factor receptor
Gene Synonyms: ERBB,ERBB1,ERRP
73 APIs:
286 Possible Orthologues:

Disease R-HSA-1643685
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
Downregulation of ERBB2 signaling R-HSA-8863795
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
Signaling by ERBB2 ECD mutants R-HSA-9665348
L1CAM interactions R-HSA-373760
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
HCMV Early Events R-HSA-9609690
GRB2 events in EGFR signaling R-HSA-179812
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PIP3 activates AKT signaling R-HSA-1257604
Membrane Trafficking R-HSA-199991
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
PI3K events in ERBB2 signaling R-HSA-1963642
Gene expression (Transcription) R-HSA-74160
EGFR interacts with phospholipase C-gamma R-HSA-212718
Signaling by Nuclear Receptors R-HSA-9006931
ESR-mediated signaling R-HSA-8939211
Developmental Biology R-HSA-1266738
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Intracellular signaling by second messengers R-HSA-9006925
Signal transduction by L1 R-HSA-445144
Extra-nuclear estrogen signaling R-HSA-9009391
Nervous system development R-HSA-9675108
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Signaling by PTK6 R-HSA-8848021
EGFR Transactivation by Gastrin R-HSA-2179392
G alpha (q) signalling events R-HSA-416476
Axon guidance R-HSA-422475
HCMV Infection R-HSA-9609646
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by EGFRvIII in Cancer R-HSA-5637812
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by GPCR R-HSA-372790
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Signal Transduction R-HSA-162582
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by ERBB2 in Cancer R-HSA-1227990
ERBB2 Regulates Cell Motility R-HSA-6785631
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by ERBB4 R-HSA-1236394
RNA Polymerase II Transcription R-HSA-73857
Signaling by EGFR in Cancer R-HSA-1643713
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB2 KD Mutants R-HSA-9664565
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by NOTCH3 R-HSA-9012852
PTK6 promotes HIF1A stabilization R-HSA-8857538
GPCR downstream signalling R-HSA-388396
Infectious disease R-HSA-5663205
SHC1 events in ERBB2 signaling R-HSA-1250196
SHC1 events in EGFR signaling R-HSA-180336
Vesicle-mediated transport R-HSA-5653656
GAB1 signalosome R-HSA-180292
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
PLCG1 events in ERBB2 signaling R-HSA-1251932
EGFR downregulation R-HSA-182971
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by ERBB2 R-HSA-1227986
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by EGFR R-HSA-177929
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by NOTCH R-HSA-157118
Generic Transcription Pathway R-HSA-212436
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SHC1 events in ERBB2 signaling R-HSA-1250196
EGFR interacts with phospholipase C-gamma R-HSA-212718
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by ERBB2 R-HSA-1227986
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by PTK6 R-HSA-8848021
GPCR downstream signalling R-HSA-388396
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
PI3K/AKT Signaling in Cancer R-HSA-2219528
Developmental Biology R-HSA-1266738
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by NOTCH R-HSA-157118
PIP3 activates AKT signaling R-HSA-1257604
Signal transduction by L1 R-HSA-445144
Membrane Trafficking R-HSA-199991
Signaling by ERBB4 R-HSA-1236394
Signaling by EGFRvIII in Cancer R-HSA-5637812
Vesicle-mediated transport R-HSA-5653656
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
L1CAM interactions R-HSA-373760
EGFR Transactivation by Gastrin R-HSA-2179392
Signaling by Nuclear Receptors R-HSA-9006931
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
ESR-mediated signaling R-HSA-8939211
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
HCMV Infection R-HSA-9609646
Signaling by ERBB2 in Cancer R-HSA-1227990
RNA Polymerase II Transcription R-HSA-73857
Signaling by EGFR R-HSA-177929
Signaling by GPCR R-HSA-372790
Axon guidance R-HSA-422475
GRB2 events in ERBB2 signaling R-HSA-1963640
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Infectious disease R-HSA-5663205
Signaling by NOTCH3 R-HSA-9012852
G alpha (q) signalling events R-HSA-416476
MAPK1/MAPK3 signaling R-HSA-5684996
Clathrin-mediated endocytosis R-HSA-8856828
Constitutive Signaling by EGFRvIII R-HSA-5637810
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
EGFR downregulation R-HSA-182971
GAB1 signalosome R-HSA-180292
GRB2 events in EGFR signaling R-HSA-179812
Downregulation of ERBB2 signaling R-HSA-8863795
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Nervous system development R-HSA-9675108
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Extra-nuclear estrogen signaling R-HSA-9009391
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ERBB2 ECD mutants R-HSA-9665348
PTK6 promotes HIF1A stabilization R-HSA-8857538
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
HCMV Early Events R-HSA-9609690
SHC1 events in EGFR signaling R-HSA-180336
PLCG1 events in ERBB2 signaling R-HSA-1251932
Signaling by ERBB2 KD Mutants R-HSA-9664565
Constitutive Signaling by EGFRvIII R-HSA-5637810
Infectious disease R-HSA-5663205
Signaling by Nuclear Receptors R-HSA-9006931
EGFR Transactivation by Gastrin R-HSA-2179392
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
SHC1 events in ERBB2 signaling R-HSA-1250196
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
ERBB2 Activates PTK6 Signaling R-HSA-8847993
PLCG1 events in ERBB2 signaling R-HSA-1251932
L1CAM interactions R-HSA-373760
EGFR downregulation R-HSA-182971
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by EGFR R-HSA-177929
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by EGFRvIII in Cancer R-HSA-5637812
Axon guidance R-HSA-422475
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
GRB2 events in EGFR signaling R-HSA-179812
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
ESR-mediated signaling R-HSA-8939211
RNA Polymerase II Transcription R-HSA-73857
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by EGFR in Cancer R-HSA-1643713
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by ERBB4 R-HSA-1236394
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Downregulation of ERBB2 signaling R-HSA-8863795
Vesicle-mediated transport R-HSA-5653656
GPCR downstream signalling R-HSA-388396
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
Signaling by PTK6 R-HSA-8848021
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
ERBB2 Regulates Cell Motility R-HSA-6785631
Generic Transcription Pathway R-HSA-212436
HCMV Early Events R-HSA-9609690
Signaling by NOTCH R-HSA-157118
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Developmental Biology R-HSA-1266738
Signal transduction by L1 R-HSA-445144
GRB2 events in ERBB2 signaling R-HSA-1963640
MAPK family signaling cascades R-HSA-5683057
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
RAF/MAP kinase cascade R-HSA-5673001
Signaling by ERBB2 ECD mutants R-HSA-9665348
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K events in ERBB2 signaling R-HSA-1963642
Gene expression (Transcription) R-HSA-74160
Membrane Trafficking R-HSA-199991
GAB1 signalosome R-HSA-180292
SHC1 events in EGFR signaling R-HSA-180336
Signaling by ERBB2 R-HSA-1227986
EGFR interacts with phospholipase C-gamma R-HSA-212718
Extra-nuclear estrogen signaling R-HSA-9009391
HCMV Infection R-HSA-9609646
MAPK1/MAPK3 signaling R-HSA-5684996
PTK6 promotes HIF1A stabilization R-HSA-8857538
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by EGFR in Cancer R-HSA-1643713
Constitutive Signaling by EGFRvIII R-HSA-5637810
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Infectious disease R-HSA-5663205
Signaling by GPCR R-HSA-372790
Signaling by ERBB2 KD Mutants R-HSA-9664565
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by EGFRvIII in Cancer R-HSA-5637812
G alpha (q) signalling events R-HSA-416476
Axon guidance R-HSA-422475
Vesicle-mediated transport R-HSA-5653656
HCMV Early Events R-HSA-9609690
Signaling by ERBB4 R-HSA-1236394
Signaling by EGFR R-HSA-177929
L1CAM interactions R-HSA-373760
GRB2 events in EGFR signaling R-HSA-179812
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH3 R-HSA-9012852
Disease R-HSA-1643685
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
GAB1 signalosome R-HSA-180292
SHC1 events in EGFR signaling R-HSA-180336
Signaling by PTK6 R-HSA-8848021
PLCG1 events in ERBB2 signaling R-HSA-1251932
PTK6 promotes HIF1A stabilization R-HSA-8857538
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH R-HSA-157118
Signal transduction by L1 R-HSA-445144
SHC1 events in ERBB2 signaling R-HSA-1250196
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by ERBB2 ECD mutants R-HSA-9665348
Intracellular signaling by second messengers R-HSA-9006925
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Membrane Trafficking R-HSA-199991
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
ERBB2 Regulates Cell Motility R-HSA-6785631
Generic Transcription Pathway R-HSA-212436
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by ERBB2 R-HSA-1227986
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Extra-nuclear estrogen signaling R-HSA-9009391
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Downregulation of ERBB2 signaling R-HSA-8863795
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EGFR downregulation R-HSA-182971
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI3K events in ERBB2 signaling R-HSA-1963642
EGFR interacts with phospholipase C-gamma R-HSA-212718
Signaling by Nuclear Receptors R-HSA-9006931
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
GPCR downstream signalling R-HSA-388396
ESR-mediated signaling R-HSA-8939211
EGFR Transactivation by Gastrin R-HSA-2179392
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
HCMV Infection R-HSA-9609646
Signaling by ERBB2 in Cancer R-HSA-1227990
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Vesicle-mediated transport R-HSA-5653656
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SHC1 events in EGFR signaling R-HSA-180336
ERBB2 Regulates Cell Motility R-HSA-6785631
RNA Polymerase II Transcription R-HSA-73857
PI3K/AKT Signaling in Cancer R-HSA-2219528
Generic Transcription Pathway R-HSA-212436
Signaling by ERBB2 ECD mutants R-HSA-9665348
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Signal Transduction R-HSA-162582
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
PLCG1 events in ERBB2 signaling R-HSA-1251932
GAB1 signalosome R-HSA-180292
HCMV Early Events R-HSA-9609690
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by Nuclear Receptors R-HSA-9006931
SHC1 events in ERBB2 signaling R-HSA-1250196
G alpha (q) signalling events R-HSA-416476
Signaling by PTK6 R-HSA-8848021
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signal transduction by L1 R-HSA-445144
Signaling by GPCR R-HSA-372790
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
PTK6 promotes HIF1A stabilization R-HSA-8857538
L1CAM interactions R-HSA-373760
Signaling by NOTCH R-HSA-157118
PI3K events in ERBB2 signaling R-HSA-1963642
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Infectious disease R-HSA-5663205
Signaling by EGFR in Cancer R-HSA-1643713
Disease R-HSA-1643685
ESR-mediated signaling R-HSA-8939211
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by EGFR R-HSA-177929
EGFR downregulation R-HSA-182971
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Developmental Biology R-HSA-1266738
EGFR Transactivation by Gastrin R-HSA-2179392
Intracellular signaling by second messengers R-HSA-9006925
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by ERBB2 KD Mutants R-HSA-9664565
Membrane Trafficking R-HSA-199991
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Extra-nuclear estrogen signaling R-HSA-9009391
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
GRB2 events in EGFR signaling R-HSA-179812
Signaling by ERBB4 R-HSA-1236394
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by EGFRvIII in Cancer R-HSA-5637812
Gene expression (Transcription) R-HSA-74160
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Downregulation of ERBB2 signaling R-HSA-8863795
Signaling by NOTCH3 R-HSA-9012852
Signaling by ERBB2 R-HSA-1227986
EGFR interacts with phospholipase C-gamma R-HSA-212718
HCMV Infection R-HSA-9609646
GPCR downstream signalling R-HSA-388396
Constitutive Signaling by EGFRvIII R-HSA-5637810
Axon guidance R-HSA-422475
EGFR interacts with phospholipase C-gamma R-HSA-212718
G alpha (q) signalling events R-HSA-416476
Signaling by ERBB4 R-HSA-1236394
SHC1 events in ERBB2 signaling R-HSA-1250196
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by Nuclear Receptors R-HSA-9006931
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Signaling by ERBB2 ECD mutants R-HSA-9665348
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by EGFR R-HSA-177929
Signaling by ERBB2 KD Mutants R-HSA-9664565
RAF/MAP kinase cascade R-HSA-5673001
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
GRB2 events in ERBB2 signaling R-HSA-1963640
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by ERBB2 R-HSA-1227986
ERBB2 Activates PTK6 Signaling R-HSA-8847993
PLCG1 events in ERBB2 signaling R-HSA-1251932
HCMV Early Events R-HSA-9609690
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PTK6 promotes HIF1A stabilization R-HSA-8857538
Signaling by ERBB2 in Cancer R-HSA-1227990
Signal transduction by L1 R-HSA-445144
ERBB2 Regulates Cell Motility R-HSA-6785631
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
GRB2 events in EGFR signaling R-HSA-179812
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Generic Transcription Pathway R-HSA-212436
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Axon guidance R-HSA-422475
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
ESR-mediated signaling R-HSA-8939211
Signaling by NOTCH R-HSA-157118
Signaling by EGFRvIII in Cancer R-HSA-5637812
Developmental Biology R-HSA-1266738
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by GPCR R-HSA-372790
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by PTK6 R-HSA-8848021
PI3K events in ERBB2 signaling R-HSA-1963642
Infectious disease R-HSA-5663205
L1CAM interactions R-HSA-373760
EGFR downregulation R-HSA-182971
EGFR Transactivation by Gastrin R-HSA-2179392
SHC1 events in EGFR signaling R-HSA-180336
Membrane Trafficking R-HSA-199991
Vesicle-mediated transport R-HSA-5653656
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Constitutive Signaling by EGFRvIII R-HSA-5637810
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by NOTCH3 R-HSA-9012852
Downregulation of ERBB2 signaling R-HSA-8863795
GAB1 signalosome R-HSA-180292
GPCR downstream signalling R-HSA-388396
HCMV Infection R-HSA-9609646
Signaling by Nuclear Receptors R-HSA-9006931
MAPK family signaling cascades R-HSA-5683057
ESR-mediated signaling R-HSA-8939211
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signaling by ERBB2 R-HSA-1227986
Signaling by NOTCH3 R-HSA-9012852
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by EGFR in Cancer R-HSA-1643713
HCMV Infection R-HSA-9609646
Membrane Trafficking R-HSA-199991
ERBB2 Regulates Cell Motility R-HSA-6785631
PI3K/AKT Signaling in Cancer R-HSA-2219528
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
SHC1 events in ERBB2 signaling R-HSA-1250196
PTK6 promotes HIF1A stabilization R-HSA-8857538
Signaling by NOTCH R-HSA-157118
GRB2 events in EGFR signaling R-HSA-179812
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Vesicle-mediated transport R-HSA-5653656
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by ERBB2 in Cancer R-HSA-1227990
Constitutive Signaling by EGFRvIII R-HSA-5637810
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
G alpha (q) signalling events R-HSA-416476
Generic Transcription Pathway R-HSA-212436
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Signal Transduction R-HSA-162582
L1CAM interactions R-HSA-373760
EGFR downregulation R-HSA-182971
Extra-nuclear estrogen signaling R-HSA-9009391
PI3K events in ERBB2 signaling R-HSA-1963642
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by EGFRvIII in Cancer R-HSA-5637812
Disease R-HSA-1643685
SHC1 events in EGFR signaling R-HSA-180336
Signaling by GPCR R-HSA-372790
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EGFR interacts with phospholipase C-gamma R-HSA-212718
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by PTK6 R-HSA-8848021
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
GRB2 events in ERBB2 signaling R-HSA-1963640
Clathrin-mediated endocytosis R-HSA-8856828
GAB1 signalosome R-HSA-180292
Downregulation of ERBB2 signaling R-HSA-8863795
PLCG1 events in ERBB2 signaling R-HSA-1251932
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by EGFR R-HSA-177929
GPCR downstream signalling R-HSA-388396
EGFR Transactivation by Gastrin R-HSA-2179392
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
Signal transduction by L1 R-HSA-445144
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
HCMV Early Events R-HSA-9609690
Signaling by ERBB4 R-HSA-1236394
Negative regulation of the PI3K/AKT network R-HSA-199418
Downregulation of ERBB2 signaling R-HSA-8863795
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K events in ERBB2 signaling R-HSA-1963642
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by EGFR R-HSA-177929
PTK6 promotes HIF1A stabilization R-HSA-8857538
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
GAB1 signalosome R-HSA-180292
RNA Polymerase II Transcription R-HSA-73857
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by ERBB4 R-HSA-1236394
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by EGFRvIII in Cancer R-HSA-5637812
Signaling by GPCR R-HSA-372790
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
GPCR downstream signalling R-HSA-388396
Signaling by EGFR in Cancer R-HSA-1643713
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH3 R-HSA-9012852
SHC1 events in ERBB2 signaling R-HSA-1250196
Signaling by ERBB2 in Cancer R-HSA-1227990
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal Transduction R-HSA-162582
Signaling by ERBB2 R-HSA-1227986
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Extra-nuclear estrogen signaling R-HSA-9009391
Generic Transcription Pathway R-HSA-212436
L1CAM interactions R-HSA-373760
Signaling by ERBB2 KD Mutants R-HSA-9664565
Nervous system development R-HSA-9675108
MAPK1/MAPK3 signaling R-HSA-5684996
EGFR downregulation R-HSA-182971
G alpha (q) signalling events R-HSA-416476
Signal transduction by L1 R-HSA-445144
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
GRB2 events in ERBB2 signaling R-HSA-1963640
Intracellular signaling by second messengers R-HSA-9006925
EGFR interacts with phospholipase C-gamma R-HSA-212718
RAF/MAP kinase cascade R-HSA-5673001
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
PLCG1 events in ERBB2 signaling R-HSA-1251932
GRB2 events in EGFR signaling R-HSA-179812
EGFR Transactivation by Gastrin R-HSA-2179392
HCMV Early Events R-HSA-9609690
SHC1 events in EGFR signaling R-HSA-180336
Signaling by NOTCH R-HSA-157118
MAPK family signaling cascades R-HSA-5683057
Signaling by PTK6 R-HSA-8848021
Clathrin-mediated endocytosis R-HSA-8856828
Disease R-HSA-1643685
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Membrane Trafficking R-HSA-199991
Axon guidance R-HSA-422475
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Vesicle-mediated transport R-HSA-5653656
HCMV Infection R-HSA-9609646
ESR-mediated signaling R-HSA-8939211
Intracellular signaling by second messengers R-HSA-9006925
Nervous system development R-HSA-9675108
EGFR Transactivation by Gastrin R-HSA-2179392
PLCG1 events in ERBB2 signaling R-HSA-1251932
Signal transduction by L1 R-HSA-445144
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
GPCR downstream signalling R-HSA-388396
HCMV Infection R-HSA-9609646
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
MAPK1/MAPK3 signaling R-HSA-5684996
PIP3 activates AKT signaling R-HSA-1257604
Signaling by PTK6 R-HSA-8848021
EGFR interacts with phospholipase C-gamma R-HSA-212718
HCMV Early Events R-HSA-9609690
EGFR downregulation R-HSA-182971
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by ERBB4 R-HSA-1236394
Axon guidance R-HSA-422475
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
PTK6 promotes HIF1A stabilization R-HSA-8857538
GRB2 events in EGFR signaling R-HSA-179812
MAPK family signaling cascades R-HSA-5683057
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
RNA Polymerase II Transcription R-HSA-73857
Clathrin-mediated endocytosis R-HSA-8856828
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Downregulation of ERBB2 signaling R-HSA-8863795
Signaling by EGFR R-HSA-177929
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Nuclear Receptors R-HSA-9006931
Generic Transcription Pathway R-HSA-212436
SHC1 events in EGFR signaling R-HSA-180336
Vesicle-mediated transport R-HSA-5653656
Signaling by EGFR in Cancer R-HSA-1643713
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by NOTCH R-HSA-157118
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB2 in Cancer R-HSA-1227990
ERBB2 Regulates Cell Motility R-HSA-6785631
ESR-mediated signaling R-HSA-8939211
L1CAM interactions R-HSA-373760
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by NOTCH3 R-HSA-9012852
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
GAB1 signalosome R-HSA-180292
Signaling by GPCR R-HSA-372790
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by ERBB2 R-HSA-1227986
Signaling by ERBB2 KD Mutants R-HSA-9664565
Disease R-HSA-1643685
SHC1 events in ERBB2 signaling R-HSA-1250196
Gene expression (Transcription) R-HSA-74160
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Membrane Trafficking R-HSA-199991
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by EGFRvIII in Cancer R-HSA-5637812
Extra-nuclear estrogen signaling R-HSA-9009391
Constitutive Signaling by EGFRvIII R-HSA-5637810
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Infectious disease R-HSA-5663205
Signaling by EGFRvIII in Cancer R-HSA-5637812
Signaling by EGFR in Cancer R-HSA-1643713
Intracellular signaling by second messengers R-HSA-9006925
Downregulation of ERBB2 signaling R-HSA-8863795
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by NOTCH R-HSA-157118
EGFR downregulation R-HSA-182971
GRB2 events in ERBB2 signaling R-HSA-1963640
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by ERBB2 in Cancer R-HSA-1227990
Infectious disease R-HSA-5663205
Signaling by ERBB2 R-HSA-1227986
Generic Transcription Pathway R-HSA-212436
Clathrin-mediated endocytosis R-HSA-8856828
RNA Polymerase II Transcription R-HSA-73857
Signaling by ERBB4 R-HSA-1236394
PTK6 promotes HIF1A stabilization R-HSA-8857538
SHC1 events in ERBB2 signaling R-HSA-1250196
Disease R-HSA-1643685
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
ERBB2 Regulates Cell Motility R-HSA-6785631
Gene expression (Transcription) R-HSA-74160
Vesicle-mediated transport R-HSA-5653656
Axon guidance R-HSA-422475
Signaling by PTK6 R-HSA-8848021
HCMV Infection R-HSA-9609646
MAPK family signaling cascades R-HSA-5683057
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
HCMV Early Events R-HSA-9609690
RAF/MAP kinase cascade R-HSA-5673001
EGFR interacts with phospholipase C-gamma R-HSA-212718
Membrane Trafficking R-HSA-199991
Constitutive Signaling by EGFRvIII R-HSA-5637810
PI3K events in ERBB2 signaling R-HSA-1963642
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
GAB1 signalosome R-HSA-180292
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signal transduction by L1 R-HSA-445144
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by GPCR R-HSA-372790
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
GPCR downstream signalling R-HSA-388396
Signaling by NOTCH3 R-HSA-9012852
Signal Transduction R-HSA-162582
EGFR Transactivation by Gastrin R-HSA-2179392
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
L1CAM interactions R-HSA-373760
Signaling by EGFR R-HSA-177929
G alpha (q) signalling events R-HSA-416476
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Negative regulation of the PI3K/AKT network R-HSA-199418
PLCG1 events in ERBB2 signaling R-HSA-1251932
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
GRB2 events in EGFR signaling R-HSA-179812
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
ESR-mediated signaling R-HSA-8939211
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SHC1 events in EGFR signaling R-HSA-180336

Expression Atlas ENSG00000146648
LRG display in Ensembl gene LRG_304
NCBI gene (formerly Entrezgene) 1956
GeneCards 3236
HGNC Symbol HGNC:3236
MIM gene 131550
MIM morbid 616069
UniProtKB Gene Name Q504U8
WikiGene 1956
Gene: AURKA
Ensembl ID : ENSG00000087586
Description: aurora kinase A
Gene Synonyms: AIK,ARK1,AURA,BTAK,PPP1R47,STK15,STK6,STK7
10 APIs:
229 Possible Orthologues:

APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Mitotic G2-G2/M phases R-HSA-453274
Interaction between PHLDA1 and AURKA R-HSA-8854521
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Regulation of TP53 Activity R-HSA-5633007
Gene expression (Transcription) R-HSA-74160
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
AURKA Activation by TPX2 R-HSA-8854518
Post-translational protein modification R-HSA-597592
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of mitotic cell cycle R-HSA-453276
RNA Polymerase II Transcription R-HSA-73857
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Interaction between PHLDA1 and AURKA R-HSA-8854521
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Transcriptional Regulation by TP53 R-HSA-3700989
Cell Cycle, Mitotic R-HSA-69278
AURKA Activation by TPX2 R-HSA-8854518
Regulation of TP53 Activity R-HSA-5633007
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
Mitotic G2-G2/M phases R-HSA-453274
Gene expression (Transcription) R-HSA-74160
SUMOylation of DNA replication proteins R-HSA-4615885
Post-translational protein modification R-HSA-597592
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
G2/M Transition R-HSA-69275
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G2/M Transition R-HSA-69275
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Interaction between PHLDA1 and AURKA R-HSA-8854521
Generic Transcription Pathway R-HSA-212436
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Transcriptional Regulation by TP53 R-HSA-3700989
Post-translational protein modification R-HSA-597592
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Cell Cycle R-HSA-1640170
SUMOylation of DNA replication proteins R-HSA-4615885
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G2-G2/M phases R-HSA-453274
SUMOylation R-HSA-2990846
AURKA Activation by TPX2 R-HSA-8854518
RNA Polymerase II Transcription R-HSA-73857
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cell Cycle, Mitotic R-HSA-69278
Regulation of TP53 Activity R-HSA-5633007
Regulation of mitotic cell cycle R-HSA-453276
AURKA Activation by TPX2 R-HSA-8854518
Interaction between PHLDA1 and AURKA R-HSA-8854521
Cell Cycle R-HSA-1640170
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation of DNA replication proteins R-HSA-4615885
Post-translational protein modification R-HSA-597592
Regulation of TP53 Activity R-HSA-5633007
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Cell Cycle, Mitotic R-HSA-69278
Metabolism of proteins R-HSA-392499
G2/M Transition R-HSA-69275
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by TP53 R-HSA-3700989
SUMOylation R-HSA-2990846
Gene expression (Transcription) R-HSA-74160
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
RNA Polymerase II Transcription R-HSA-73857
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Regulation of TP53 Activity R-HSA-5633007
AURKA Activation by TPX2 R-HSA-8854518
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Post-translational protein modification R-HSA-597592
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of mitotic cell cycle R-HSA-453276
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Cell Cycle R-HSA-1640170
Metabolism of proteins R-HSA-392499
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Mitotic G2-G2/M phases R-HSA-453274
G2/M Transition R-HSA-69275
Gene expression (Transcription) R-HSA-74160
Cell Cycle, Mitotic R-HSA-69278
SUMOylation R-HSA-2990846
Interaction between PHLDA1 and AURKA R-HSA-8854521
Transcriptional Regulation by TP53 R-HSA-3700989
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Metabolism of proteins R-HSA-392499
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Interaction between PHLDA1 and AURKA R-HSA-8854521
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Post-translational protein modification R-HSA-597592
SUMOylation of DNA replication proteins R-HSA-4615885
AURKA Activation by TPX2 R-HSA-8854518
Regulation of mitotic cell cycle R-HSA-453276
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SUMOylation R-HSA-2990846
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity R-HSA-5633007
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Mitotic G2-G2/M phases R-HSA-453274
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
AURKA Activation by TPX2 R-HSA-8854518
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Generic Transcription Pathway R-HSA-212436
Cell Cycle, Mitotic R-HSA-69278
Mitotic G2-G2/M phases R-HSA-453274
SUMOylation R-HSA-2990846
Transcriptional Regulation by TP53 R-HSA-3700989
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of TP53 Activity R-HSA-5633007
Metabolism of proteins R-HSA-392499
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Regulation of mitotic cell cycle R-HSA-453276
Interaction between PHLDA1 and AURKA R-HSA-8854521
G2/M Transition R-HSA-69275
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Metabolism of proteins R-HSA-392499
Interaction between PHLDA1 and AURKA R-HSA-8854521
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Post-translational protein modification R-HSA-597592
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of TP53 Activity R-HSA-5633007
G2/M Transition R-HSA-69275
Regulation of mitotic cell cycle R-HSA-453276
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AURKA Activation by TPX2 R-HSA-8854518
Transcriptional Regulation by TP53 R-HSA-3700989
Gene expression (Transcription) R-HSA-74160
SUMOylation R-HSA-2990846
Mitotic G2-G2/M phases R-HSA-453274
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
AURKA Activation by TPX2 R-HSA-8854518
RNA Polymerase II Transcription R-HSA-73857
Regulation of mitotic cell cycle R-HSA-453276
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G2/M Transition R-HSA-69275
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
SUMOylation R-HSA-2990846
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of TP53 Activity R-HSA-5633007
Interaction between PHLDA1 and AURKA R-HSA-8854521
Post-translational protein modification R-HSA-597592
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cell Cycle, Mitotic R-HSA-69278
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by TP53 R-HSA-3700989
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Cell Cycle R-HSA-1640170
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G2/M Transition R-HSA-69275
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of TP53 Activity R-HSA-5633007
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
RNA Polymerase II Transcription R-HSA-73857
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
AURKA Activation by TPX2 R-HSA-8854518
Interaction between PHLDA1 and AURKA R-HSA-8854521
SUMOylation R-HSA-2990846
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Metabolism of proteins R-HSA-392499
Regulation of mitotic cell cycle R-HSA-453276
Post-translational protein modification R-HSA-597592
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cell Cycle R-HSA-1640170
Post-translational protein modification R-HSA-597592
Gene expression (Transcription) R-HSA-74160
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
SUMOylation of DNA replication proteins R-HSA-4615885
Regulation of TP53 Activity R-HSA-5633007
Interaction between PHLDA1 and AURKA R-HSA-8854521
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic G2-G2/M phases R-HSA-453274
RNA Polymerase II Transcription R-HSA-73857
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle, Mitotic R-HSA-69278
Transcriptional Regulation by TP53 R-HSA-3700989
Metabolism of proteins R-HSA-392499
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
G2/M Transition R-HSA-69275
Generic Transcription Pathway R-HSA-212436
SUMOylation R-HSA-2990846
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
AURKA Activation by TPX2 R-HSA-8854518

Expression Atlas ENSG00000087586
NCBI gene (formerly Entrezgene) 6790
GeneCards 11393
HGNC Symbol HGNC:11393
MIM gene 603072
MIM morbid 114500
UniProtKB Gene Name Q5QPD4
WikiGene 6790
Gene: EML4
Ensembl ID : ENSG00000143924
Description: EMAP like 4
Gene Synonyms: C2ORF2,ELP120,ROPP120
5 APIs:
214 Possible Orthologues:

ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK in cancer R-HSA-9700206
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Mitotic Prometaphase R-HSA-68877
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
ALK mutants bind TKIs R-HSA-9700645
Disease R-HSA-1643685
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK fusions and activated point mutants R-HSA-9725370
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Cell Cycle R-HSA-1640170
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
M Phase R-HSA-68886
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Cell Cycle, Mitotic R-HSA-69278
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Mitotic Prometaphase R-HSA-68877
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
ALK mutants bind TKIs R-HSA-9700645
M Phase R-HSA-68886
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK in cancer R-HSA-9700206
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Cell Cycle, Mitotic R-HSA-69278
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
ALK mutants bind TKIs R-HSA-9700645
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Mitotic Prometaphase R-HSA-68877
Cell Cycle, Mitotic R-HSA-69278
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
ALK mutants bind TKIs R-HSA-9700645
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by ALK in cancer R-HSA-9700206
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Signaling by ALK in cancer R-HSA-9700206
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Disease R-HSA-1643685
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Cell Cycle R-HSA-1640170
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
M Phase R-HSA-68886

Expression Atlas ENSG00000143924
NCBI gene (formerly Entrezgene) 27436
GeneCards 1316
HGNC Symbol HGNC:1316
MIM gene 607442
UniProtKB Gene Name Q9HC35
WikiGene 27436
Gene: PDGFRB
Ensembl ID : ENSG00000113721
Description: platelet derived growth factor receptor beta
Gene Synonyms: CD140B,JTK12,PDGFR,PDGFR1
40 APIs:
247 Possible Orthologues:

Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Downstream signal transduction R-HSA-186763
Signaling by PDGF R-HSA-186797
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAF/MAP kinase cascade R-HSA-5673001
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by PDGF R-HSA-186797
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Downstream signal transduction R-HSA-186763
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Downstream signal transduction R-HSA-186763
MAPK family signaling cascades R-HSA-5683057
Signaling by PDGF R-HSA-186797
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Negative regulation of the PI3K/AKT network R-HSA-199418
PIP3 activates AKT signaling R-HSA-1257604
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
MAPK1/MAPK3 signaling R-HSA-5684996
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGF R-HSA-186797
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signal transduction R-HSA-186763
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by PDGF R-HSA-186797
Downstream signal transduction R-HSA-186763
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
Downstream signal transduction R-HSA-186763
Disease R-HSA-1643685
Signaling by PDGF R-HSA-186797
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by PDGF R-HSA-186797
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Downstream signal transduction R-HSA-186763
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF/MAP kinase cascade R-HSA-5673001
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by PDGF R-HSA-186797
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Intracellular signaling by second messengers R-HSA-9006925
Downstream signal transduction R-HSA-186763
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Signaling by PDGF R-HSA-186797
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signal transduction R-HSA-186763
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RAF/MAP kinase cascade R-HSA-5673001
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK family signaling cascades R-HSA-5683057
Signaling by PDGF R-HSA-186797
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signal transduction R-HSA-186763
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604

Expression Atlas ENSG00000113721
NCBI gene (formerly Entrezgene) 5159
GeneCards 8804
HGNC Symbol HGNC:8804
MIM gene 173410
MIM morbid 616592
UniProtKB Gene Name P09619
WikiGene 5159
Gene: FLT4
Ensembl ID : ENSG00000037280
Description: fms related receptor tyrosine kinase 4
Gene Synonyms: PCL,VEGFR-3,VEGFR3
46 APIs:
198 Possible Orthologues:

Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by NOTCH4 R-HSA-9013694
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH R-HSA-157118
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by VEGF R-HSA-194138
Signaling by NOTCH R-HSA-157118
Signaling by VEGF R-HSA-194138
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signal Transduction R-HSA-162582
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by NOTCH4 R-HSA-9013694
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by VEGF R-HSA-194138
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
Signaling by VEGF R-HSA-194138
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH R-HSA-157118
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by NOTCH4 R-HSA-9013694
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH R-HSA-157118
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by VEGF R-HSA-194138
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by VEGF R-HSA-194138
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694

Expression Atlas ENSG00000037280
NCBI gene (formerly Entrezgene) 2324
GeneCards 3767
HGNC Symbol HGNC:3767
MIM gene 136352
MIM morbid 618780
UniProtKB Gene Name P35916
WikiGene 2324
Ensembl ID : ENSG00000089022
Description: MAPK activated protein kinase 5
Gene Synonyms: MK5,PRAK
1 APIs:
179 Possible Orthologues:

Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Oxidative Stress Induced Senescence R-HSA-2559580
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
MAPK family signaling cascades R-HSA-5683057
Cellular Senescence R-HSA-2559583
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity R-HSA-5633007
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK6/MAPK4 signaling R-HSA-5687128
MAPK6/MAPK4 signaling R-HSA-5687128
Oxidative Stress Induced Senescence R-HSA-2559580
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity R-HSA-5633007
Regulation of TP53 Activity R-HSA-5633007
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stress R-HSA-2262752
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Cellular Senescence R-HSA-2559583
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity R-HSA-5633007
Oxidative Stress Induced Senescence R-HSA-2559580
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
MAPK family signaling cascades R-HSA-5683057
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Cellular Senescence R-HSA-2559583
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of TP53 Activity R-HSA-5633007
MAPK family signaling cascades R-HSA-5683057
Transcriptional Regulation by TP53 R-HSA-3700989
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
MAPK6/MAPK4 signaling R-HSA-5687128
Oxidative Stress Induced Senescence R-HSA-2559580
Transcriptional Regulation by TP53 R-HSA-3700989
MAPK family signaling cascades R-HSA-5683057
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
Oxidative Stress Induced Senescence R-HSA-2559580
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of TP53 Activity R-HSA-5633007
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Oxidative Stress Induced Senescence R-HSA-2559580
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stimuli R-HSA-8953897
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Regulation of TP53 Activity R-HSA-5633007
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583

Expression Atlas ENSG00000089022
NCBI gene (formerly Entrezgene) 8550
GeneCards 6889
HGNC Symbol HGNC:6889
MIM gene 606723
MIM morbid 619869
UniProtKB Gene Name R4GN93
WikiGene 8550