Gene: MAPK3
Ensembl ID : ENSG00000102882
Description: mitogen-activated protein kinase 3
Gene Synonyms: ERK1,P44ERK1,P44MAPK,PRKM3
6 APIs:
199 Possible Orthologues:

ERK/MAPK targets R-HSA-198753
M Phase R-HSA-68886
Disease R-HSA-1643685
Signaling by RAS mutants R-HSA-6802949
Signaling by NODAL R-HSA-1181150
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
G alpha (q) signalling events R-HSA-416476
ESR-mediated signaling R-HSA-8939211
Signal attenuation R-HSA-74749
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Growth hormone receptor signaling R-HSA-982772
GPCR downstream signalling R-HSA-388396
Negative regulation of MAPK pathway R-HSA-5675221
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR3 R-HSA-5654741
Signaling by TGF-beta Receptor Complex R-HSA-170834
ISG15 antiviral mechanism R-HSA-1169408
RUNX2 regulates bone development R-HSA-8941326
Toll-like Receptor Cascades R-HSA-168898
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Negative regulation of FGFR3 signaling R-HSA-5654732
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Disease R-HSA-1643685
Signaling by Nuclear Receptors R-HSA-9006931
Activation of the AP-1 family of transcription factors R-HSA-450341
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by FGFR1 R-HSA-5654736
Signaling by Activin R-HSA-1502540
Signaling by NTRKs R-HSA-166520
L1CAM interactions R-HSA-373760
MAPK3 (ERK1) activation R-HSA-110056
Interferon Signaling R-HSA-913531
Frs2-mediated activation R-HSA-170968
Signalling to ERKs R-HSA-187687
RNA Polymerase I Promoter Opening R-HSA-73728
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ALK in cancer R-HSA-9700206
Cell Cycle, Mitotic R-HSA-69278
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
NCAM signaling for neurite out-growth R-HSA-375165
Cellular responses to stress R-HSA-2262752
Signaling downstream of RAS mutants R-HSA-9649948
Negative regulation of the PI3K/AKT network R-HSA-199418
MyD88 cascade initiated on plasma membrane R-HSA-975871
Formation of apoptosome R-HSA-111458
ERK/MAPK targets R-HSA-198753
Response of Mtb to phagocytosis R-HSA-9637690
M Phase R-HSA-68886
Post NMDA receptor activation events R-HSA-438064
Transcriptional regulation by RUNX2 R-HSA-8878166
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Suppression of apoptosis R-HSA-9635465
Cellular Senescence R-HSA-2559583
Nervous system development R-HSA-9675108
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Hemostasis R-HSA-109582
Intrinsic Pathway for Apoptosis R-HSA-109606
RNA Polymerase I Promoter Clearance R-HSA-73854
Regulation of the apoptosome activity R-HSA-9627069
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-17 signaling R-HSA-448424
Innate Immune System R-HSA-168249
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Neuronal System R-HSA-112316
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF-independent MAPK1/3 activation R-HSA-112409
Leishmania phagocytosis R-HSA-9664417
MAPK family signaling cascades R-HSA-5683057
Generic Transcription Pathway R-HSA-212436
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Immune System R-HSA-168256
Signaling by TGFB family members R-HSA-9006936
Signal transduction by L1 R-HSA-445144
Signaling by FGFR4 R-HSA-5654743
Oxidative Stress Induced Senescence R-HSA-2559580
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Cytochrome c-mediated apoptotic response R-HSA-111461
MAP kinase activation R-HSA-450294
Insulin receptor signalling cascade R-HSA-74751
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Insulin receptor R-HSA-74752
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RNA Polymerase I Transcription R-HSA-73864
MyD88-independent TLR4 cascade R-HSA-166166
Transmission across Chemical Synapses R-HSA-112315
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by Interleukins R-HSA-449147
Signaling by FGFR2 R-HSA-5654738
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Leishmania infection R-HSA-9658195
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Apoptotic factor-mediated response R-HSA-111471
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by GPCR R-HSA-372790
RHO GTPase Effectors R-HSA-195258
Oncogene Induced Senescence R-HSA-2559585
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
PTEN Regulation R-HSA-6807070
Developmental Biology R-HSA-1266738
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Cellular response to heat stress R-HSA-3371556
NPAS4 regulates expression of target genes R-HSA-9768919
ERKs are inactivated R-HSA-202670
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Programmed Cell Death R-HSA-5357801
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MAP2K and MAPK activation R-HSA-5674135
RAF/MAP kinase cascade R-HSA-5673001
FCGR3A-mediated phagocytosis R-HSA-9664422
Negative regulation of FGFR1 signaling R-HSA-5654726
Parasite infection R-HSA-9664407
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
Signaling by MAP2K mutants R-HSA-9652169
Axon guidance R-HSA-422475
Infection with Mycobacterium tuberculosis R-HSA-9635486
Oncogenic MAPK signaling R-HSA-6802957
Apoptosis R-HSA-109581
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cell Cycle R-HSA-1640170
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Prolonged ERK activation events R-HSA-169893
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Negative regulation of FGFR4 signaling R-HSA-5654733
FCERI mediated MAPK activation R-HSA-2871796
Infectious disease R-HSA-5663205
Negative regulation of FGFR2 signaling R-HSA-5654727
Mitotic Prophase R-HSA-68875
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Signaling by FGFR R-HSA-190236
Transcriptional Regulation by NPAS4 R-HSA-9634815
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by NTRK1 (TRKA) R-HSA-187037
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
RSK activation R-HSA-444257
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Frs2-mediated activation R-HSA-170968
Cell Cycle, Mitotic R-HSA-69278
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by RAS mutants R-HSA-6802949
Interleukin-17 signaling R-HSA-448424
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Signaling by GPCR R-HSA-372790
Growth hormone receptor signaling R-HSA-982772
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by FGFR3 R-HSA-5654741
Suppression of apoptosis R-HSA-9635465
Transcriptional regulation by RUNX2 R-HSA-8878166
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
M Phase R-HSA-68886
Cellular response to heat stress R-HSA-3371556
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RSK activation R-HSA-444257
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by TGFB family members R-HSA-9006936
Signal transduction by L1 R-HSA-445144
FCGR3A-mediated phagocytosis R-HSA-9664422
Response of Mtb to phagocytosis R-HSA-9637690
Regulation of PTEN gene transcription R-HSA-8943724
Negative feedback regulation of MAPK pathway R-HSA-5674499
MAP2K and MAPK activation R-HSA-5674135
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Rho GTPases R-HSA-194315
Signaling by Insulin receptor R-HSA-74752
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Axon guidance R-HSA-422475
Programmed Cell Death R-HSA-5357801
NPAS4 regulates expression of target genes R-HSA-9768919
Neuronal System R-HSA-112316
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Hemostasis R-HSA-109582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Immune System R-HSA-168256
Cytochrome c-mediated apoptotic response R-HSA-111461
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal attenuation R-HSA-74749
Formation of apoptosome R-HSA-111458
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by ALK in cancer R-HSA-9700206
Signaling by Nuclear Receptors R-HSA-9006931
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cellular Senescence R-HSA-2559583
Signaling by MAP2K mutants R-HSA-9652169
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Transmission across Chemical Synapses R-HSA-112315
Signaling by FGFR R-HSA-190236
FCERI mediated MAPK activation R-HSA-2871796
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Cellular responses to stress R-HSA-2262752
Signaling by FGFR2 R-HSA-5654738
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
ERK/MAPK targets R-HSA-198753
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by NTRKs R-HSA-166520
Transcriptional Regulation by NPAS4 R-HSA-9634815
GPCR downstream signalling R-HSA-388396
MyD88-independent TLR4 cascade R-HSA-166166
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
PTEN Regulation R-HSA-6807070
Cell Cycle R-HSA-1640170
Negative regulation of FGFR1 signaling R-HSA-5654726
L1CAM interactions R-HSA-373760
Negative regulation of FGFR3 signaling R-HSA-5654732
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signalling to ERKs R-HSA-187687
Post NMDA receptor activation events R-HSA-438064
Oncogenic MAPK signaling R-HSA-6802957
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Interferon Signaling R-HSA-913531
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
RNA Polymerase I Promoter Opening R-HSA-73728
Activation of the AP-1 family of transcription factors R-HSA-450341
RNA Polymerase I Promoter Clearance R-HSA-73854
ERKs are inactivated R-HSA-202670
MyD88 dependent cascade initiated on endosome R-HSA-975155
ESR-mediated signaling R-HSA-8939211
Negative regulation of FGFR4 signaling R-HSA-5654733
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Activin R-HSA-1502540
Signaling by NTRK1 (TRKA) R-HSA-187037
Gene expression (Transcription) R-HSA-74160
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Negative regulation of FGFR2 signaling R-HSA-5654727
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK family signaling cascades R-HSA-5683057
Signaling by Interleukins R-HSA-449147
Insulin receptor signalling cascade R-HSA-74751
G alpha (q) signalling events R-HSA-416476
Signaling by NODAL R-HSA-1181150
PIP3 activates AKT signaling R-HSA-1257604
Regulation of the apoptosome activity R-HSA-9627069
Signaling by FGFR4 R-HSA-5654743
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK1/MAPK3 signaling R-HSA-5684996
NCAM signaling for neurite out-growth R-HSA-375165
Oncogene Induced Senescence R-HSA-2559585
Apoptosis R-HSA-109581
RNA Polymerase I Transcription R-HSA-73864
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Intrinsic Pathway for Apoptosis R-HSA-109606
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Parasite infection R-HSA-9664407
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Infection with Mycobacterium tuberculosis R-HSA-9635486
RHO GTPase Effectors R-HSA-195258
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Innate Immune System R-HSA-168249
Negative regulation of MAPK pathway R-HSA-5675221
Spry regulation of FGF signaling R-HSA-1295596
Leishmania phagocytosis R-HSA-9664417
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by FGFR1 R-HSA-5654736
MAP kinase activation R-HSA-450294
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by ALK fusions and activated point mutants R-HSA-9725370
ISG15 antiviral mechanism R-HSA-1169408
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Cytokine Signaling in Immune system R-HSA-1280215
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Negative regulation of the PI3K/AKT network R-HSA-199418
Toll-like Receptor Cascades R-HSA-168898
RAF/MAP kinase cascade R-HSA-5673001
Leishmania infection R-HSA-9658195
Generic Transcription Pathway R-HSA-212436
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Apoptotic factor-mediated response R-HSA-111471
MAPK3 (ERK1) activation R-HSA-110056
Platelet activation, signaling and aggregation R-HSA-76002
RUNX2 regulates bone development R-HSA-8941326
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Prolonged ERK activation events R-HSA-169893
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Growth hormone receptor signaling R-HSA-982772
MyD88 cascade initiated on plasma membrane R-HSA-975871
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
ISG15 antiviral mechanism R-HSA-1169408
Negative regulation of FGFR4 signaling R-HSA-5654733
Platelet activation, signaling and aggregation R-HSA-76002
RNA Polymerase I Promoter Opening R-HSA-73728
Parasite infection R-HSA-9664407
Axon guidance R-HSA-422475
RNA Polymerase I Promoter Clearance R-HSA-73854
Negative feedback regulation of MAPK pathway R-HSA-5674499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Prolonged ERK activation events R-HSA-169893
Toll-like Receptor Cascades R-HSA-168898
Signal transduction by L1 R-HSA-445144
Cellular Senescence R-HSA-2559583
NCAM signaling for neurite out-growth R-HSA-375165
L1CAM interactions R-HSA-373760
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Gene expression (Transcription) R-HSA-74160
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Signaling by NTRK1 (TRKA) R-HSA-187037
Cell Cycle R-HSA-1640170
Formation of apoptosome R-HSA-111458
Interleukin-17 signaling R-HSA-448424
Transcriptional regulation by RUNX2 R-HSA-8878166
NPAS4 regulates expression of target genes R-HSA-9768919
Hemostasis R-HSA-109582
Cellular responses to stimuli R-HSA-8953897
RAF-independent MAPK1/3 activation R-HSA-112409
Signalling to ERKs R-HSA-187687
Signaling by FGFR2 R-HSA-5654738
Negative regulation of MAPK pathway R-HSA-5675221
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Transmission across Chemical Synapses R-HSA-112315
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signaling by Insulin receptor R-HSA-74752
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Cytokine Signaling in Immune system R-HSA-1280215
ERK/MAPK targets R-HSA-198753
Signaling by Activin R-HSA-1502540
Interferon Signaling R-HSA-913531
Signaling by GPCR R-HSA-372790
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stress R-HSA-2262752
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Rho GTPases R-HSA-194315
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Transcriptional Regulation by NPAS4 R-HSA-9634815
RHO GTPase Effectors R-HSA-195258
Signal attenuation R-HSA-74749
Oncogenic MAPK signaling R-HSA-6802957
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling downstream of RAS mutants R-HSA-9649948
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAP kinase activation R-HSA-450294
Signaling by RAS mutants R-HSA-6802949
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Leishmania infection R-HSA-9658195
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by FGFR4 R-HSA-5654743
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by NODAL R-HSA-1181150
RUNX2 regulates bone development R-HSA-8941326
ERKs are inactivated R-HSA-202670
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by MAP2K mutants R-HSA-9652169
Signaling by FGFR1 R-HSA-5654736
Signaling by TGF-beta Receptor Complex R-HSA-170834
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Extra-nuclear estrogen signaling R-HSA-9009391
Nervous system development R-HSA-9675108
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Oncogene Induced Senescence R-HSA-2559585
Cell Cycle, Mitotic R-HSA-69278
Disease R-HSA-1643685
Signaling by FGFR3 R-HSA-5654741
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
PIP3 activates AKT signaling R-HSA-1257604
ESR-mediated signaling R-HSA-8939211
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RSK activation R-HSA-444257
Immune System R-HSA-168256
RAF/MAP kinase cascade R-HSA-5673001
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by NTRKs R-HSA-166520
Apoptotic factor-mediated response R-HSA-111471
Negative regulation of FGFR1 signaling R-HSA-5654726
Leishmania phagocytosis R-HSA-9664417
Programmed Cell Death R-HSA-5357801
Signaling by TGFB family members R-HSA-9006936
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Innate Immune System R-HSA-168249
Neuronal System R-HSA-112316
Oxidative Stress Induced Senescence R-HSA-2559580
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RNA Polymerase II Transcription R-HSA-73857
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Cytochrome c-mediated apoptotic response R-HSA-111461
M Phase R-HSA-68886
Post NMDA receptor activation events R-HSA-438064
G alpha (q) signalling events R-HSA-416476
Spry regulation of FGF signaling R-HSA-1295596
FCERI mediated MAPK activation R-HSA-2871796
PTEN Regulation R-HSA-6807070
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Cellular response to heat stress R-HSA-3371556
Suppression of apoptosis R-HSA-9635465
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Response of Mtb to phagocytosis R-HSA-9637690
MAPK3 (ERK1) activation R-HSA-110056
Signaling by RAF1 mutants R-HSA-9656223
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MAP2K and MAPK activation R-HSA-5674135
Signaling by ALK in cancer R-HSA-9700206
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR R-HSA-190236
Intracellular signaling by second messengers R-HSA-9006925
Regulation of the apoptosome activity R-HSA-9627069
Infectious disease R-HSA-5663205
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
RNA Polymerase I Transcription R-HSA-73864
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Negative regulation of FGFR2 signaling R-HSA-5654727
FCGR3A-mediated phagocytosis R-HSA-9664422
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Developmental Biology R-HSA-1266738
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Apoptosis R-HSA-109581
Signaling by ALK fusions and activated point mutants R-HSA-9725370
MAPK family signaling cascades R-HSA-5683057
Frs2-mediated activation R-HSA-170968
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
Mitotic Prophase R-HSA-68875
Negative regulation of the PI3K/AKT network R-HSA-199418
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Regulation of the apoptosome activity R-HSA-9627069
Signaling by RAF1 mutants R-HSA-9656223
Parasite infection R-HSA-9664407
Signaling by NTRKs R-HSA-166520
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Generic Transcription Pathway R-HSA-212436
Signaling by NODAL R-HSA-1181150
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
FCGR3A-mediated phagocytosis R-HSA-9664422
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Apoptosis R-HSA-109581
Oncogenic MAPK signaling R-HSA-6802957
Signaling by MAP2K mutants R-HSA-9652169
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Signaling by FGFR4 R-HSA-5654743
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Apoptotic factor-mediated response R-HSA-111471
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by FGFR2 R-HSA-5654738
Negative feedback regulation of MAPK pathway R-HSA-5674499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NCAM signaling for neurite out-growth R-HSA-375165
RNA Polymerase I Transcription R-HSA-73864
Cellular response to heat stress R-HSA-3371556
Neuronal System R-HSA-112316
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MyD88 cascade initiated on plasma membrane R-HSA-975871
RNA Polymerase I Promoter Clearance R-HSA-73854
Cell Cycle, Mitotic R-HSA-69278
RSK activation R-HSA-444257
Programmed Cell Death R-HSA-5357801
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signal transduction by L1 R-HSA-445144
Infectious disease R-HSA-5663205
Formation of apoptosome R-HSA-111458
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RUNX2 regulates osteoblast differentiation R-HSA-8940973
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by Insulin receptor R-HSA-74752
Regulation of PTEN gene transcription R-HSA-8943724
Interferon Signaling R-HSA-913531
Oxidative Stress Induced Senescence R-HSA-2559580
NPAS4 regulates expression of target genes R-HSA-9768919
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling downstream of RAS mutants R-HSA-9649948
Frs2-mediated activation R-HSA-170968
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 dependent cascade initiated on endosome R-HSA-975155
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
MAP kinase activation R-HSA-450294
RNA Polymerase I Promoter Opening R-HSA-73728
Signaling by BRAF and RAF1 fusions R-HSA-6802952
ISG15 antiviral mechanism R-HSA-1169408
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
ERKs are inactivated R-HSA-202670
Leishmania phagocytosis R-HSA-9664417
Leishmania infection R-HSA-9658195
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FGFR R-HSA-190236
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
L1CAM interactions R-HSA-373760
Insulin receptor signalling cascade R-HSA-74751
MAPK family signaling cascades R-HSA-5683057
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular responses to stimuli R-HSA-8953897
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signal attenuation R-HSA-74749
Intracellular signaling by second messengers R-HSA-9006925
Growth hormone receptor signaling R-HSA-982772
Signaling by NTRK1 (TRKA) R-HSA-187037
Prolonged ERK activation events R-HSA-169893
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAP2K and MAPK activation R-HSA-5674135
RAF/MAP kinase cascade R-HSA-5673001
Hemostasis R-HSA-109582
Toll-like Receptor Cascades R-HSA-168898
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by Rho GTPases R-HSA-194315
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Axon guidance R-HSA-422475
MAPK3 (ERK1) activation R-HSA-110056
Signaling by FGFR3 R-HSA-5654741
ESR-mediated signaling R-HSA-8939211
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
M Phase R-HSA-68886
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RHO GTPase Effectors R-HSA-195258
Mitotic Prophase R-HSA-68875
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by RAS mutants R-HSA-6802949
Platelet activation, signaling and aggregation R-HSA-76002
Innate Immune System R-HSA-168249
Post NMDA receptor activation events R-HSA-438064
Negative regulation of FGFR3 signaling R-HSA-5654732
Oncogene Induced Senescence R-HSA-2559585
Negative regulation of FGFR2 signaling R-HSA-5654727
Signalling to ERKs R-HSA-187687
Cellular Senescence R-HSA-2559583
Signaling by ALK in cancer R-HSA-9700206
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Activin R-HSA-1502540
Transcriptional regulation by RUNX2 R-HSA-8878166
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by FGFR1 R-HSA-5654736
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Interleukins R-HSA-449147
Negative regulation of MAPK pathway R-HSA-5675221
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Transmission across Chemical Synapses R-HSA-112315
FCERI mediated MAPK activation R-HSA-2871796
Suppression of apoptosis R-HSA-9635465
RUNX2 regulates bone development R-HSA-8941326
Signaling by TGF-beta Receptor Complex R-HSA-170834
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Response of Mtb to phagocytosis R-HSA-9637690
Transcriptional Regulation by NPAS4 R-HSA-9634815
RAF-independent MAPK1/3 activation R-HSA-112409
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
ERK/MAPK targets R-HSA-198753
Signaling by TGFB family members R-HSA-9006936
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Spry regulation of FGF signaling R-HSA-1295596
PIP3 activates AKT signaling R-HSA-1257604
Activation of the AP-1 family of transcription factors R-HSA-450341
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
RNA Polymerase II Transcription R-HSA-73857
Extra-nuclear estrogen signaling R-HSA-9009391
Interleukin-17 signaling R-HSA-448424
FCERI mediated MAPK activation R-HSA-2871796
Developmental Biology R-HSA-1266738
Signaling by NTRK1 (TRKA) R-HSA-187037
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR4 signaling R-HSA-5654733
Prolonged ERK activation events R-HSA-169893
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cellular responses to stress R-HSA-2262752
Signaling by GPCR R-HSA-372790
Negative feedback regulation of MAPK pathway R-HSA-5674499
RNA Polymerase I Transcription R-HSA-73864
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by TGFB family members R-HSA-9006936
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll-like Receptor Cascades R-HSA-168898
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
M Phase R-HSA-68886
Signaling by FGFR4 R-HSA-5654743
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Apoptosis R-HSA-109581
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of NMDA receptors and postsynaptic events R-HSA-442755
ESR-mediated signaling R-HSA-8939211
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Activin R-HSA-1502540
Cytokine Signaling in Immune system R-HSA-1280215
Oncogene Induced Senescence R-HSA-2559585
MAP kinase activation R-HSA-450294
Immune System R-HSA-168256
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MAPK3 (ERK1) activation R-HSA-110056
Neuronal System R-HSA-112316
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MAPK family signaling cascades R-HSA-5683057
Signaling by TGF-beta Receptor Complex R-HSA-170834
Negative regulation of MAPK pathway R-HSA-5675221
RUNX2 regulates bone development R-HSA-8941326
Interferon Signaling R-HSA-913531
RAF-independent MAPK1/3 activation R-HSA-112409
Generic Transcription Pathway R-HSA-212436
Signaling by FGFR R-HSA-190236
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Infection with Mycobacterium tuberculosis R-HSA-9635486
Negative regulation of FGFR1 signaling R-HSA-5654726
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Cellular responses to stimuli R-HSA-8953897
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular Senescence R-HSA-2559583
MyD88 cascade initiated on plasma membrane R-HSA-975871
Intracellular signaling by second messengers R-HSA-9006925
Signalling to ERKs R-HSA-187687
Signal attenuation R-HSA-74749
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Leishmania infection R-HSA-9658195
Regulation of the apoptosome activity R-HSA-9627069
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
MyD88 dependent cascade initiated on endosome R-HSA-975155
Hemostasis R-HSA-109582
Signaling by Nuclear Receptors R-HSA-9006931
Frs2-mediated activation R-HSA-170968
Post NMDA receptor activation events R-HSA-438064
Transmission across Chemical Synapses R-HSA-112315
Signaling by NODAL R-HSA-1181150
Suppression of apoptosis R-HSA-9635465
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by FGFR3 R-HSA-5654741
Infectious disease R-HSA-5663205
Signaling by ALK in cancer R-HSA-9700206
GPCR downstream signalling R-HSA-388396
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Transcriptional regulation by RUNX2 R-HSA-8878166
RSK activation R-HSA-444257
FCGR3A-mediated phagocytosis R-HSA-9664422
Oncogenic MAPK signaling R-HSA-6802957
Formation of apoptosome R-HSA-111458
Negative regulation of FGFR2 signaling R-HSA-5654727
Regulation of PTEN gene transcription R-HSA-8943724
Programmed Cell Death R-HSA-5357801
Signal transduction by L1 R-HSA-445144
Interleukin-17 signaling R-HSA-448424
Signaling by Rho GTPases R-HSA-194315
Cell Cycle, Mitotic R-HSA-69278
Insulin receptor signalling cascade R-HSA-74751
Negative regulation of the PI3K/AKT network R-HSA-199418
MAP2K and MAPK activation R-HSA-5674135
NPAS4 regulates expression of target genes R-HSA-9768919
Transcriptional Regulation by NPAS4 R-HSA-9634815
Activation of the AP-1 family of transcription factors R-HSA-450341
Disease R-HSA-1643685
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Negative regulation of FGFR3 signaling R-HSA-5654732
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by RAF1 mutants R-HSA-9656223
Intrinsic Pathway for Apoptosis R-HSA-109606
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Extra-nuclear estrogen signaling R-HSA-9009391
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Response of Mtb to phagocytosis R-HSA-9637690
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MAPK1/MAPK3 signaling R-HSA-5684996
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Mitotic Prophase R-HSA-68875
RHO GTPase Effectors R-HSA-195258
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by MAP2K mutants R-HSA-9652169
MyD88-independent TLR4 cascade R-HSA-166166
RAF/MAP kinase cascade R-HSA-5673001
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Oxidative Stress Induced Senescence R-HSA-2559580
Apoptotic factor-mediated response R-HSA-111471
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Axon guidance R-HSA-422475
L1CAM interactions R-HSA-373760
Leishmania phagocytosis R-HSA-9664417
Signal Transduction R-HSA-162582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Spry regulation of FGF signaling R-HSA-1295596
ERKs are inactivated R-HSA-202670
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by NTRKs R-HSA-166520
Growth hormone receptor signaling R-HSA-982772
Signaling by Insulin receptor R-HSA-74752
Parasite infection R-HSA-9664407
Signaling by RAS mutants R-HSA-6802949
Innate Immune System R-HSA-168249
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by FGFR2 R-HSA-5654738
Cytochrome c-mediated apoptotic response R-HSA-111461
RNA Polymerase I Promoter Opening R-HSA-73728
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by FGFR1 R-HSA-5654736
Nervous system development R-HSA-9675108
ISG15 antiviral mechanism R-HSA-1169408
Cell Cycle R-HSA-1640170
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Transcriptional Regulation by NPAS4 R-HSA-9634815
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
ESR-mediated signaling R-HSA-8939211
MAP2K and MAPK activation R-HSA-5674135
Developmental Biology R-HSA-1266738
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
RNA Polymerase I Promoter Opening R-HSA-73728
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Interleukin-17 signaling R-HSA-448424
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Neuronal System R-HSA-112316
RSK activation R-HSA-444257
MyD88-independent TLR4 cascade R-HSA-166166
Post NMDA receptor activation events R-HSA-438064
Signaling by Insulin receptor R-HSA-74752
RUNX2 regulates bone development R-HSA-8941326
Oxidative Stress Induced Senescence R-HSA-2559580
Activation of the AP-1 family of transcription factors R-HSA-450341
Activation of NMDA receptors and postsynaptic events R-HSA-442755
M Phase R-HSA-68886
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Activin R-HSA-1502540
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signal attenuation R-HSA-74749
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Interferon Signaling R-HSA-913531
Growth hormone receptor signaling R-HSA-982772
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by FGFR4 R-HSA-5654743
Signaling by RAF1 mutants R-HSA-9656223
Oncogenic MAPK signaling R-HSA-6802957
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Spry regulation of FGF signaling R-HSA-1295596
MAP kinase activation R-HSA-450294
Apoptotic factor-mediated response R-HSA-111471
RNA Polymerase II Transcription R-HSA-73857
Infection with Mycobacterium tuberculosis R-HSA-9635486
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
FCGR3A-mediated phagocytosis R-HSA-9664422
GPCR downstream signalling R-HSA-388396
Signaling by FGFR3 R-HSA-5654741
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Innate Immune System R-HSA-168249
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR1 R-HSA-5654736
ERK/MAPK targets R-HSA-198753
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Extra-nuclear estrogen signaling R-HSA-9009391
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RUNX2 regulates osteoblast differentiation R-HSA-8940973
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by NTRKs R-HSA-166520
Leishmania infection R-HSA-9658195
Programmed Cell Death R-HSA-5357801
Parasite infection R-HSA-9664407
MyD88 dependent cascade initiated on endosome R-HSA-975155
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by TGFB family members R-HSA-9006936
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NCAM signaling for neurite out-growth R-HSA-375165
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
L1CAM interactions R-HSA-373760
Signal Transduction R-HSA-162582
Frs2-mediated activation R-HSA-170968
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll-like Receptor Cascades R-HSA-168898
Negative regulation of MAPK pathway R-HSA-5675221
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
FCERI mediated MAPK activation R-HSA-2871796
Signaling by MAP2K mutants R-HSA-9652169
Signaling by ALK in cancer R-HSA-9700206
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Cellular Senescence R-HSA-2559583
Infectious disease R-HSA-5663205
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Generic Transcription Pathway R-HSA-212436
Intrinsic Pathway for Apoptosis R-HSA-109606
Mitotic Prophase R-HSA-68875
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by GPCR R-HSA-372790
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling downstream of RAS mutants R-HSA-9649948
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RNA Polymerase I Transcription R-HSA-73864
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by RAS mutants R-HSA-6802949
ERKs are inactivated R-HSA-202670
Cell Cycle, Mitotic R-HSA-69278
Regulation of PTEN gene transcription R-HSA-8943724
Negative regulation of FGFR3 signaling R-HSA-5654732
MAPK family signaling cascades R-HSA-5683057
Negative regulation of FGFR1 signaling R-HSA-5654726
RAF/MAP kinase cascade R-HSA-5673001
Formation of apoptosome R-HSA-111458
Signaling by Nuclear Receptors R-HSA-9006931
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by NTRK1 (TRKA) R-HSA-187037
Immune System R-HSA-168256
Signaling by TGF-beta Receptor Complex R-HSA-170834
PIP3 activates AKT signaling R-HSA-1257604
MAPK3 (ERK1) activation R-HSA-110056
RAF-independent MAPK1/3 activation R-HSA-112409
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
MAPK1/MAPK3 signaling R-HSA-5684996
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cytochrome c-mediated apoptotic response R-HSA-111461
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of the apoptosome activity R-HSA-9627069
Signal transduction by L1 R-HSA-445144
Hemostasis R-HSA-109582
Oncogene Induced Senescence R-HSA-2559585
RHO GTPase Effectors R-HSA-195258
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Suppression of apoptosis R-HSA-9635465
Signaling by FGFR R-HSA-190236
Apoptosis R-HSA-109581
G alpha (q) signalling events R-HSA-416476
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Nervous system development R-HSA-9675108
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
PTEN Regulation R-HSA-6807070
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by FGFR2 R-HSA-5654738
Prolonged ERK activation events R-HSA-169893
Negative regulation of FGFR4 signaling R-HSA-5654733
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular response to heat stress R-HSA-3371556
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by Rho GTPases R-HSA-194315
Signaling by NODAL R-HSA-1181150
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Transmission across Chemical Synapses R-HSA-112315
Leishmania phagocytosis R-HSA-9664417
Response of Mtb to phagocytosis R-HSA-9637690
Cellular responses to stimuli R-HSA-8953897
Signalling to ERKs R-HSA-187687
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
FCGR3A-mediated phagocytosis R-HSA-9664422
Prolonged ERK activation events R-HSA-169893
Programmed Cell Death R-HSA-5357801
Signaling by NTRKs R-HSA-166520
Negative regulation of FGFR2 signaling R-HSA-5654727
Neuronal System R-HSA-112316
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Activin R-HSA-1502540
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by FGFR4 R-HSA-5654743
Apoptotic factor-mediated response R-HSA-111471
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Oncogene Induced Senescence R-HSA-2559585
Response of Mtb to phagocytosis R-HSA-9637690
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
ERKs are inactivated R-HSA-202670
Apoptosis R-HSA-109581
RHO GTPase Effectors R-HSA-195258
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by ALK fusions and activated point mutants R-HSA-9725370
RNA Polymerase II Transcription R-HSA-73857
MyD88 dependent cascade initiated on endosome R-HSA-975155
Formation of apoptosome R-HSA-111458
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Extra-nuclear estrogen signaling R-HSA-9009391
RSK activation R-HSA-444257
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Toll-like Receptor Cascades R-HSA-168898
Cell Cycle R-HSA-1640170
Innate Immune System R-HSA-168249
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Axon guidance R-HSA-422475
Signaling by ALK in cancer R-HSA-9700206
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
L1CAM interactions R-HSA-373760
Infection with Mycobacterium tuberculosis R-HSA-9635486
RNA Polymerase I Promoter Opening R-HSA-73728
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Frs2-mediated activation R-HSA-170968
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Hemostasis R-HSA-109582
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR3 R-HSA-5654741
ESR-mediated signaling R-HSA-8939211
Signaling by FGFR R-HSA-190236
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
RNA Polymerase I Transcription R-HSA-73864
Signaling by RAF1 mutants R-HSA-9656223
MAPK family signaling cascades R-HSA-5683057
Cellular Senescence R-HSA-2559583
Platelet activation, signaling and aggregation R-HSA-76002
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by NODAL R-HSA-1181150
Signalling to ERKs R-HSA-187687
Nervous system development R-HSA-9675108
Negative regulation of MAPK pathway R-HSA-5675221
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cell Cycle, Mitotic R-HSA-69278
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G alpha (q) signalling events R-HSA-416476
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Signaling by FGFR1 R-HSA-5654736
Insulin receptor signalling cascade R-HSA-74751
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Spry regulation of FGF signaling R-HSA-1295596
Cellular responses to stress R-HSA-2262752
GPCR downstream signalling R-HSA-388396
Intracellular signaling by second messengers R-HSA-9006925
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
MAP2K and MAPK activation R-HSA-5674135
Signaling by FGFR2 R-HSA-5654738
RUNX2 regulates bone development R-HSA-8941326
Activation of the AP-1 family of transcription factors R-HSA-450341
Suppression of apoptosis R-HSA-9635465
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-17 signaling R-HSA-448424
Disease R-HSA-1643685
Leishmania infection R-HSA-9658195
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signal attenuation R-HSA-74749
Signaling by Nuclear Receptors R-HSA-9006931
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by RAS mutants R-HSA-6802949
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK3 (ERK1) activation R-HSA-110056
Signaling by Rho GTPases R-HSA-194315
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Regulation of the apoptosome activity R-HSA-9627069
Growth hormone receptor signaling R-HSA-982772
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by MAP2K mutants R-HSA-9652169
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
ERK/MAPK targets R-HSA-198753
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Leishmania phagocytosis R-HSA-9664417
Cellular responses to stimuli R-HSA-8953897
Signaling by Interleukins R-HSA-449147
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signal transduction by L1 R-HSA-445144
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by GPCR R-HSA-372790
Negative feedback regulation of MAPK pathway R-HSA-5674499
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Negative regulation of FGFR1 signaling R-HSA-5654726
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RNA Polymerase I Promoter Clearance R-HSA-73854
Parasite infection R-HSA-9664407
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by TGFB family members R-HSA-9006936
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated MAPK activation R-HSA-2871796
MAP kinase activation R-HSA-450294
Transcriptional Regulation by NPAS4 R-HSA-9634815
Negative regulation of the PI3K/AKT network R-HSA-199418
Interferon Signaling R-HSA-913531
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intrinsic Pathway for Apoptosis R-HSA-109606
Post NMDA receptor activation events R-HSA-438064
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Infectious disease R-HSA-5663205
Transmission across Chemical Synapses R-HSA-112315
Regulation of PTEN gene transcription R-HSA-8943724
Oncogenic MAPK signaling R-HSA-6802957
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Extra-nuclear estrogen signaling R-HSA-9009391
Interferon Signaling R-HSA-913531
Transmission across Chemical Synapses R-HSA-112315
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR1 R-HSA-5654736
Apoptotic factor-mediated response R-HSA-111471
Signal transduction by L1 R-HSA-445144
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Rho GTPases R-HSA-194315
Leishmania phagocytosis R-HSA-9664417
MAPK family signaling cascades R-HSA-5683057
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
RNA Polymerase I Promoter Opening R-HSA-73728
Signaling by NODAL R-HSA-1181150
Immune System R-HSA-168256
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Post NMDA receptor activation events R-HSA-438064
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Hemostasis R-HSA-109582
Suppression of apoptosis R-HSA-9635465
Activation of the AP-1 family of transcription factors R-HSA-450341
PTEN Regulation R-HSA-6807070
Programmed Cell Death R-HSA-5357801
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by NTRKs R-HSA-166520
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Oncogenic MAPK signaling R-HSA-6802957
RNA Polymerase I Transcription R-HSA-73864
Interleukin-17 signaling R-HSA-448424
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR4 R-HSA-5654743
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Negative regulation of the PI3K/AKT network R-HSA-199418
Platelet activation, signaling and aggregation R-HSA-76002
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Insulin receptor R-HSA-74752
FCERI mediated MAPK activation R-HSA-2871796
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Frs2-mediated activation R-HSA-170968
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling downstream of RAS mutants R-HSA-9649948
Developmental Biology R-HSA-1266738
Negative regulation of FGFR1 signaling R-HSA-5654726
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Nuclear Receptors R-HSA-9006931
Mitotic Prophase R-HSA-68875
Neuronal System R-HSA-112316
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Growth hormone receptor signaling R-HSA-982772
MAP kinase activation R-HSA-450294
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll-like Receptor Cascades R-HSA-168898
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
MAPK3 (ERK1) activation R-HSA-110056
Signaling by FGFR3 R-HSA-5654741
Signaling by FGFR2 R-HSA-5654738
Parasite infection R-HSA-9664407
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by ALK in cancer R-HSA-9700206
Signaling by TGFB family members R-HSA-9006936
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by RAS mutants R-HSA-6802949
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
RUNX2 regulates bone development R-HSA-8941326
L1CAM interactions R-HSA-373760
Gene expression (Transcription) R-HSA-74160
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Prolonged ERK activation events R-HSA-169893
ERK/MAPK targets R-HSA-198753
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Oncogene Induced Senescence R-HSA-2559585
Negative feedback regulation of MAPK pathway R-HSA-5674499
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular response to heat stress R-HSA-3371556
Transcriptional regulation by RUNX2 R-HSA-8878166
Response of Mtb to phagocytosis R-HSA-9637690
Intracellular signaling by second messengers R-HSA-9006925
RAF-independent MAPK1/3 activation R-HSA-112409
RSK activation R-HSA-444257
Signaling by MAP2K mutants R-HSA-9652169
Nervous system development R-HSA-9675108
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Negative regulation of FGFR2 signaling R-HSA-5654727
MyD88 cascade initiated on plasma membrane R-HSA-975871
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of FGFR4 signaling R-HSA-5654733
Oxidative Stress Induced Senescence R-HSA-2559580
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR R-HSA-190236
Signaling by GPCR R-HSA-372790
Signaling by TGF-beta Receptor Complex R-HSA-170834
GPCR downstream signalling R-HSA-388396
Negative regulation of MAPK pathway R-HSA-5675221
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
M Phase R-HSA-68886
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Apoptosis R-HSA-109581
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Leishmania infection R-HSA-9658195
Intrinsic Pathway for Apoptosis R-HSA-109606
MyD88-independent TLR4 cascade R-HSA-166166
MAP2K and MAPK activation R-HSA-5674135
ERKs are inactivated R-HSA-202670
ESR-mediated signaling R-HSA-8939211
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
NPAS4 regulates expression of target genes R-HSA-9768919
Cellular responses to stimuli R-HSA-8953897
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Cellular Senescence R-HSA-2559583
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signalling to ERKs R-HSA-187687
Spry regulation of FGF signaling R-HSA-1295596
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Innate Immune System R-HSA-168249
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Signaling by NTRK1 (TRKA) R-HSA-187037
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
PIP3 activates AKT signaling R-HSA-1257604
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Formation of apoptosome R-HSA-111458
Regulation of the apoptosome activity R-HSA-9627069
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
RHO GTPase Effectors R-HSA-195258
MAPK1/MAPK3 signaling R-HSA-5684996
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signal attenuation R-HSA-74749
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of PTEN gene transcription R-HSA-8943724
Infection with Mycobacterium tuberculosis R-HSA-9635486
G alpha (q) signalling events R-HSA-416476
Signaling by Activin R-HSA-1502540
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR4 R-HSA-5654743
RNA Polymerase I Promoter Clearance R-HSA-73854
Activation of the AP-1 family of transcription factors R-HSA-450341
Infection with Mycobacterium tuberculosis R-HSA-9635486
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
MyD88-independent TLR4 cascade R-HSA-166166
PIP3 activates AKT signaling R-HSA-1257604
Regulation of HSF1-mediated heat shock response R-HSA-3371453
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by MAP2K mutants R-HSA-9652169
RSK activation R-HSA-444257
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MAPK family signaling cascades R-HSA-5683057
Signaling by NTRKs R-HSA-166520
Signaling by FGFR3 R-HSA-5654741
Developmental Biology R-HSA-1266738
Oncogenic MAPK signaling R-HSA-6802957
Suppression of apoptosis R-HSA-9635465
ERK/MAPK targets R-HSA-198753
Spry regulation of FGF signaling R-HSA-1295596
Disease R-HSA-1643685
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cell Cycle, Mitotic R-HSA-69278
Signaling by NTRK1 (TRKA) R-HSA-187037
Programmed Cell Death R-HSA-5357801
Axon guidance R-HSA-422475
Signaling downstream of RAS mutants R-HSA-9649948
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Oncogene Induced Senescence R-HSA-2559585
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Extra-nuclear estrogen signaling R-HSA-9009391
Signal transduction by L1 R-HSA-445144
Toll-like Receptor Cascades R-HSA-168898
Cellular response to heat stress R-HSA-3371556
Regulation of PTEN gene transcription R-HSA-8943724
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Prolonged ERK activation events R-HSA-169893
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Transmission across Chemical Synapses R-HSA-112315
Parasite infection R-HSA-9664407
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Generic Transcription Pathway R-HSA-212436
Negative regulation of the PI3K/AKT network R-HSA-199418
Cellular responses to stress R-HSA-2262752
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Frs2-mediated activation R-HSA-170968
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Intrinsic Pathway for Apoptosis R-HSA-109606
Formation of apoptosome R-HSA-111458
ISG15 antiviral mechanism R-HSA-1169408
Negative regulation of FGFR1 signaling R-HSA-5654726
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Cytokine Signaling in Immune system R-HSA-1280215
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAP kinase activation R-HSA-450294
RNA Polymerase I Promoter Opening R-HSA-73728
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
NCAM signaling for neurite out-growth R-HSA-375165
Leishmania phagocytosis R-HSA-9664417
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Interferon Signaling R-HSA-913531
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR2 signaling R-HSA-5654727
RUNX2 regulates bone development R-HSA-8941326
Interleukin-17 signaling R-HSA-448424
Immune System R-HSA-168256
Signaling by Insulin receptor R-HSA-74752
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Insulin receptor signalling cascade R-HSA-74751
Signaling by NODAL R-HSA-1181150
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Negative regulation of MAPK pathway R-HSA-5675221
Signal Transduction R-HSA-162582
Regulation of the apoptosome activity R-HSA-9627069
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Post NMDA receptor activation events R-HSA-438064
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Apoptotic factor-mediated response R-HSA-111471
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signal attenuation R-HSA-74749
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Hemostasis R-HSA-109582
MAP2K and MAPK activation R-HSA-5674135
ERKs are inactivated R-HSA-202670
Growth hormone receptor signaling R-HSA-982772
L1CAM interactions R-HSA-373760
Signaling by Rho GTPases R-HSA-194315
ESR-mediated signaling R-HSA-8939211
FCERI mediated MAPK activation R-HSA-2871796
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Response of Mtb to phagocytosis R-HSA-9637690
Neuronal System R-HSA-112316
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Cell Cycle R-HSA-1640170
RHO GTPase Effectors R-HSA-195258
Signaling by Nuclear Receptors R-HSA-9006931
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Oxidative Stress Induced Senescence R-HSA-2559580
Apoptosis R-HSA-109581
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signalling to ERKs R-HSA-187687
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
GPCR downstream signalling R-HSA-388396
RNA Polymerase I Transcription R-HSA-73864
Signaling by FGFR2 R-HSA-5654738
PTEN Regulation R-HSA-6807070
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by RAS mutants R-HSA-6802949
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by FGFR R-HSA-190236
Cytochrome c-mediated apoptotic response R-HSA-111461
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by ALK in cancer R-HSA-9700206
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by RAF1 mutants R-HSA-9656223
Cellular Senescence R-HSA-2559583
Transcriptional Regulation by NPAS4 R-HSA-9634815
Negative feedback regulation of MAPK pathway R-HSA-5674499
Cellular responses to stimuli R-HSA-8953897
Signaling by FGFR1 R-HSA-5654736
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by TGFB family members R-HSA-9006936
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Gene expression (Transcription) R-HSA-74160
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Leishmania infection R-HSA-9658195
Signaling by GPCR R-HSA-372790
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Activin R-HSA-1502540
MyD88 cascade initiated on plasma membrane R-HSA-975871
Negative regulation of FGFR3 signaling R-HSA-5654732
MAPK3 (ERK1) activation R-HSA-110056

Expression Atlas ENSG00000102882
NCBI gene (formerly Entrezgene) 5595
GeneCards 6877
HGNC Symbol HGNC:6877
MIM gene 601795
UniProtKB Gene Name P27361
WikiGene 5595
Gene: BCR
Ensembl ID : ENSG00000186716
Description: BCR activator of RhoGEF and GTPase
Gene Synonyms: ALL,BCR1,CML,D22S11,D22S662,PHL
8 APIs:
285 Possible Orthologues:

Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHOC GTPase cycle R-HSA-9013106
RAC1 GTPase cycle R-HSA-9013149
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
RHOA GTPase cycle R-HSA-8980692
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
FGFR1 mutant receptor activation R-HSA-1839124
RAC2 GTPase cycle R-HSA-9013404
CDC42 GTPase cycle R-HSA-9013148
RAC3 GTPase cycle R-HSA-9013423
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by FGFR in disease R-HSA-1226099
RHO GTPase cycle R-HSA-9012999
RHOB GTPase cycle R-HSA-9013026
RAC3 GTPase cycle R-HSA-9013423
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by FGFR in disease R-HSA-1226099
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHOA GTPase cycle R-HSA-8980692
Signaling by Rho GTPases R-HSA-194315
RHOC GTPase cycle R-HSA-9013106
RHOB GTPase cycle R-HSA-9013026
CDC42 GTPase cycle R-HSA-9013148
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
FGFR1 mutant receptor activation R-HSA-1839124
RAC1 GTPase cycle R-HSA-9013149
Signaling by FGFR1 in disease R-HSA-5655302
RHO GTPase cycle R-HSA-9012999
RAC2 GTPase cycle R-HSA-9013404
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
RHOB GTPase cycle R-HSA-9013026
RAC2 GTPase cycle R-HSA-9013404
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by FGFR in disease R-HSA-1226099
RHOA GTPase cycle R-HSA-8980692
RHOC GTPase cycle R-HSA-9013106
CDC42 GTPase cycle R-HSA-9013148
RAC1 GTPase cycle R-HSA-9013149
Signaling by Rho GTPases R-HSA-194315
RAC3 GTPase cycle R-HSA-9013423
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHO GTPase cycle R-HSA-9012999
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Signaling by FGFR1 in disease R-HSA-5655302
RAC3 GTPase cycle R-HSA-9013423
RHOB GTPase cycle R-HSA-9013026
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Signaling by FGFR in disease R-HSA-1226099
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
CDC42 GTPase cycle R-HSA-9013148
RHOA GTPase cycle R-HSA-8980692
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHO GTPase cycle R-HSA-9012999
Signaling by FGFR1 in disease R-HSA-5655302
Signal Transduction R-HSA-162582
RAC1 GTPase cycle R-HSA-9013149
RHOC GTPase cycle R-HSA-9013106
RAC2 GTPase cycle R-HSA-9013404
Signaling by Rho GTPases R-HSA-194315
Disease R-HSA-1643685
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by FGFR in disease R-HSA-1226099
RHO GTPase cycle R-HSA-9012999
Signaling by FGFR1 in disease R-HSA-5655302
RAC1 GTPase cycle R-HSA-9013149
CDC42 GTPase cycle R-HSA-9013148
RAC3 GTPase cycle R-HSA-9013423
RAC2 GTPase cycle R-HSA-9013404
RHOA GTPase cycle R-HSA-8980692
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHOB GTPase cycle R-HSA-9013026
RHOC GTPase cycle R-HSA-9013106
Signal Transduction R-HSA-162582
Signaling by FGFR in disease R-HSA-1226099
RAC1 GTPase cycle R-HSA-9013149
FGFR1 mutant receptor activation R-HSA-1839124
RAC3 GTPase cycle R-HSA-9013423
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by Rho GTPases R-HSA-194315
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
CDC42 GTPase cycle R-HSA-9013148
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHO GTPase cycle R-HSA-9012999
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHOA GTPase cycle R-HSA-8980692
RHOB GTPase cycle R-HSA-9013026
RHOC GTPase cycle R-HSA-9013106
RAC2 GTPase cycle R-HSA-9013404
Disease R-HSA-1643685
RAC1 GTPase cycle R-HSA-9013149
CDC42 GTPase cycle R-HSA-9013148
Signaling by Rho GTPases R-HSA-194315
RHOA GTPase cycle R-HSA-8980692
RHOC GTPase cycle R-HSA-9013106
Signaling by FGFR1 in disease R-HSA-5655302
RHOB GTPase cycle R-HSA-9013026
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Signaling by FGFR in disease R-HSA-1226099
RHO GTPase cycle R-HSA-9012999
RAC2 GTPase cycle R-HSA-9013404
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
RAC3 GTPase cycle R-HSA-9013423
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Disease R-HSA-1643685
FGFR1 mutant receptor activation R-HSA-1839124
RHOA GTPase cycle R-HSA-8980692
RHO GTPase cycle R-HSA-9012999
Signal Transduction R-HSA-162582
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
RAC3 GTPase cycle R-HSA-9013423
CDC42 GTPase cycle R-HSA-9013148
RHOC GTPase cycle R-HSA-9013106
Signaling by FGFR in disease R-HSA-1226099
RAC2 GTPase cycle R-HSA-9013404
Signaling by FGFR1 in disease R-HSA-5655302
RAC1 GTPase cycle R-HSA-9013149
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHOB GTPase cycle R-HSA-9013026
Signaling by Rho GTPases R-HSA-194315
CDC42 GTPase cycle R-HSA-9013148
Disease R-HSA-1643685
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
RAC1 GTPase cycle R-HSA-9013149
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
Signaling by FGFR in disease R-HSA-1226099
RHOC GTPase cycle R-HSA-9013106
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by FGFR1 in disease R-HSA-5655302
RAC2 GTPase cycle R-HSA-9013404
RHOA GTPase cycle R-HSA-8980692
RAC3 GTPase cycle R-HSA-9013423
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHOB GTPase cycle R-HSA-9013026
RHO GTPase cycle R-HSA-9012999
CDC42 GTPase cycle R-HSA-9013148
RAC2 GTPase cycle R-HSA-9013404
RHOC GTPase cycle R-HSA-9013106
RHOA GTPase cycle R-HSA-8980692
Signaling by FGFR1 in disease R-HSA-5655302
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Signaling by FGFR in disease R-HSA-1226099
FGFR1 mutant receptor activation R-HSA-1839124
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
RHOB GTPase cycle R-HSA-9013026
RAC1 GTPase cycle R-HSA-9013149
RAC3 GTPase cycle R-HSA-9013423
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Rho GTPases R-HSA-194315
RHO GTPase cycle R-HSA-9012999
RHO GTPase cycle R-HSA-9012999
RHOC GTPase cycle R-HSA-9013106
FGFR1 mutant receptor activation R-HSA-1839124
RAC2 GTPase cycle R-HSA-9013404
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR1 in disease R-HSA-5655302
RAC1 GTPase cycle R-HSA-9013149
Signaling by FGFR in disease R-HSA-1226099
Signal Transduction R-HSA-162582
RHOB GTPase cycle R-HSA-9013026
Disease R-HSA-1643685
CDC42 GTPase cycle R-HSA-9013148
RAC3 GTPase cycle R-HSA-9013423
Signaling by Rho GTPases R-HSA-194315
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHOA GTPase cycle R-HSA-8980692

Expression Atlas ENSG00000186716
LRG display in Ensembl gene LRG_1112
NCBI gene (formerly Entrezgene) 613
GeneCards 1014
HGNC Symbol HGNC:1014
MIM gene 151410
MIM morbid 613065
UniProtKB Gene Name P11274
WikiGene 613
Gene: FGFR1
Ensembl ID : ENSG00000077782
Description: fibroblast growth factor receptor 1
Gene Synonyms: BFGFR,CD331,CEK,FLG,FLT2,H2,H3,H4,H5,KAL2,N-SAM
26 APIs:
293 Possible Orthologues:

MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by activated point mutants of FGFR1 R-HSA-1839122
MAPK family signaling cascades R-HSA-5683057
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR1 in disease R-HSA-5655302
Downstream signaling of activated FGFR1 R-HSA-5654687
RAF/MAP kinase cascade R-HSA-5673001
Gastrulation R-HSA-9758941
Signal Transduction R-HSA-162582
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
FGFR1 ligand binding and activation R-HSA-190242
Developmental Biology R-HSA-1266738
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K Cascade R-HSA-109704
Signaling by FGFR in disease R-HSA-1226099
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Negative regulation of the PI3K/AKT network R-HSA-199418
IGF1R signaling cascade R-HSA-2428924
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by FGFR1 R-HSA-5654736
L1CAM interactions R-HSA-373760
Signaling by FGFR R-HSA-190236
Formation of paraxial mesoderm R-HSA-9793380
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FRS-mediated FGFR1 signaling R-HSA-5654693
Axon guidance R-HSA-422475
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI-3K cascade:FGFR1 R-HSA-5654689
FGFR1b ligand binding and activation R-HSA-190370
Disease R-HSA-1643685
FGFR1c ligand binding and activation R-HSA-190373
Signal transduction by L1 R-HSA-445144
IRS-mediated signalling R-HSA-112399
Signaling by FGFR1 amplification mutants R-HSA-1839120
Signaling by Insulin receptor R-HSA-74752
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Negative regulation of FGFR1 signaling R-HSA-5654726
PI3K/AKT Signaling in Cancer R-HSA-2219528
FGFR1 mutant receptor activation R-HSA-1839124
Nervous system development R-HSA-9675108
PIP3 activates AKT signaling R-HSA-1257604
SHC-mediated cascade:FGFR1 R-HSA-5654688
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IGF1R signaling cascade R-HSA-2428924
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
PI3K/AKT Signaling in Cancer R-HSA-2219528
FRS-mediated FGFR1 signaling R-HSA-5654693
Signaling by FGFR1 in disease R-HSA-5655302
NCAM signaling for neurite out-growth R-HSA-375165
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR1 R-HSA-5654736
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR R-HSA-190236
L1CAM interactions R-HSA-373760
Signal Transduction R-HSA-162582
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Negative regulation of FGFR1 signaling R-HSA-5654726
FGFR1 mutant receptor activation R-HSA-1839124
Axon guidance R-HSA-422475
MAPK1/MAPK3 signaling R-HSA-5684996
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
IRS-mediated signalling R-HSA-112399
Signaling by FGFR in disease R-HSA-1226099
FGFR1c and Klotho ligand binding and activation R-HSA-190374
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Insulin receptor R-HSA-74752
Signal transduction by L1 R-HSA-445144
PI-3K cascade:FGFR1 R-HSA-5654689
PI3K Cascade R-HSA-109704
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
SHC-mediated cascade:FGFR1 R-HSA-5654688
MAPK family signaling cascades R-HSA-5683057
FGFR1b ligand binding and activation R-HSA-190370
FGFR1 ligand binding and activation R-HSA-190242
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Developmental Biology R-HSA-1266738
Signaling by FGFR1 amplification mutants R-HSA-1839120
Gastrulation R-HSA-9758941
FGFR1c ligand binding and activation R-HSA-190373
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by activated point mutants of FGFR1 R-HSA-1839122
Formation of paraxial mesoderm R-HSA-9793380
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
Signaling by FGFR1 amplification mutants R-HSA-1839120
Formation of paraxial mesoderm R-HSA-9793380
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Insulin receptor R-HSA-74752
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
RAF/MAP kinase cascade R-HSA-5673001
Gastrulation R-HSA-9758941
PI-3K cascade:FGFR1 R-HSA-5654689
Downstream signaling of activated FGFR1 R-HSA-5654687
SHC-mediated cascade:FGFR1 R-HSA-5654688
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by activated point mutants of FGFR1 R-HSA-1839122
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI3K Cascade R-HSA-109704
PIP3 activates AKT signaling R-HSA-1257604
FGFR1c ligand binding and activation R-HSA-190373
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
L1CAM interactions R-HSA-373760
MAPK1/MAPK3 signaling R-HSA-5684996
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by FGFR1 R-HSA-5654736
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Insulin receptor signalling cascade R-HSA-74751
FGFR1 ligand binding and activation R-HSA-190242
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR in disease R-HSA-1226099
IRS-related events triggered by IGF1R R-HSA-2428928
Signal transduction by L1 R-HSA-445144
Axon guidance R-HSA-422475
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Intracellular signaling by second messengers R-HSA-9006925
IRS-mediated signalling R-HSA-112399
Nervous system development R-HSA-9675108
IGF1R signaling cascade R-HSA-2428924
FRS-mediated FGFR1 signaling R-HSA-5654693
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Signaling by FGFR R-HSA-190236
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FGFR1b ligand binding and activation R-HSA-190370
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR R-HSA-190236
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
FRS-mediated FGFR1 signaling R-HSA-5654693
Downstream signaling of activated FGFR1 R-HSA-5654687
IRS-mediated signalling R-HSA-112399
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Signaling by Insulin receptor R-HSA-74752
PI3K Cascade R-HSA-109704
Nervous system development R-HSA-9675108
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Signal transduction by L1 R-HSA-445144
Gastrulation R-HSA-9758941
Signal Transduction R-HSA-162582
FGFR1b ligand binding and activation R-HSA-190370
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of FGFR1 signaling R-HSA-5654726
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
Intracellular signaling by second messengers R-HSA-9006925
Formation of paraxial mesoderm R-HSA-9793380
L1CAM interactions R-HSA-373760
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IGF1R signaling cascade R-HSA-2428924
Signaling by activated point mutants of FGFR1 R-HSA-1839122
IRS-related events triggered by IGF1R R-HSA-2428928
Axon guidance R-HSA-422475
Signaling by FGFR1 amplification mutants R-HSA-1839120
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by FGFR1 R-HSA-5654736
Insulin receptor signalling cascade R-HSA-74751
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Signaling by FGFR in disease R-HSA-1226099
FGFR1c ligand binding and activation R-HSA-190373
NCAM signaling for neurite out-growth R-HSA-375165
MAPK1/MAPK3 signaling R-HSA-5684996
FGFR1 ligand binding and activation R-HSA-190242
Negative regulation of the PI3K/AKT network R-HSA-199418
Developmental Biology R-HSA-1266738
MAPK family signaling cascades R-HSA-5683057
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
SHC-mediated cascade:FGFR1 R-HSA-5654688
FGFR1 mutant receptor activation R-HSA-1839124
Negative regulation of the PI3K/AKT network R-HSA-199418
Nervous system development R-HSA-9675108
FGFR1b ligand binding and activation R-HSA-190370
L1CAM interactions R-HSA-373760
Formation of paraxial mesoderm R-HSA-9793380
Signaling by activated point mutants of FGFR1 R-HSA-1839122
Signaling by FGFR1 R-HSA-5654736
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
IGF1R signaling cascade R-HSA-2428924
Intracellular signaling by second messengers R-HSA-9006925
SHC-mediated cascade:FGFR1 R-HSA-5654688
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FGFR1c ligand binding and activation R-HSA-190373
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signal transduction by L1 R-HSA-445144
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
IRS-mediated signalling R-HSA-112399
Signaling by FGFR1 in disease R-HSA-5655302
Negative regulation of FGFR1 signaling R-HSA-5654726
Signal Transduction R-HSA-162582
Gastrulation R-HSA-9758941
PI3K Cascade R-HSA-109704
Signaling by FGFR1 amplification mutants R-HSA-1839120
Developmental Biology R-HSA-1266738
Signaling by FGFR R-HSA-190236
IRS-related events triggered by IGF1R R-HSA-2428928
FRS-mediated FGFR1 signaling R-HSA-5654693
Disease R-HSA-1643685
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Insulin receptor R-HSA-74752
FGFR1 ligand binding and activation R-HSA-190242
MAPK family signaling cascades R-HSA-5683057
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Axon guidance R-HSA-422475
PI3K/AKT Signaling in Cancer R-HSA-2219528
Insulin receptor signalling cascade R-HSA-74751
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI-3K cascade:FGFR1 R-HSA-5654689
NCAM signaling for neurite out-growth R-HSA-375165
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Signaling by FGFR in disease R-HSA-1226099
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FGFR1 mutant receptor activation R-HSA-1839124
NCAM signaling for neurite out-growth R-HSA-375165
PIP3 activates AKT signaling R-HSA-1257604
Formation of paraxial mesoderm R-HSA-9793380
MAPK1/MAPK3 signaling R-HSA-5684996
Axon guidance R-HSA-422475
FGFR1c ligand binding and activation R-HSA-190373
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR R-HSA-190236
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Disease R-HSA-1643685
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR in disease R-HSA-1226099
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Insulin receptor signalling cascade R-HSA-74751
FGFR1 ligand binding and activation R-HSA-190242
Signal transduction by L1 R-HSA-445144
PI3K Cascade R-HSA-109704
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
RAF/MAP kinase cascade R-HSA-5673001
FGFR1b ligand binding and activation R-HSA-190370
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR1 amplification mutants R-HSA-1839120
Signaling by activated point mutants of FGFR1 R-HSA-1839122
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Gastrulation R-HSA-9758941
Nervous system development R-HSA-9675108
SHC-mediated cascade:FGFR1 R-HSA-5654688
Developmental Biology R-HSA-1266738
Signaling by FGFR1 R-HSA-5654736
Negative regulation of FGFR1 signaling R-HSA-5654726
FRS-mediated FGFR1 signaling R-HSA-5654693
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
L1CAM interactions R-HSA-373760
Downstream signaling of activated FGFR1 R-HSA-5654687
IRS-related events triggered by IGF1R R-HSA-2428928
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR1 in disease R-HSA-5655302
IRS-mediated signalling R-HSA-112399
PI-3K cascade:FGFR1 R-HSA-5654689
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
FGFR1 mutant receptor activation R-HSA-1839124
Formation of paraxial mesoderm R-HSA-9793380
Signaling by FGFR1 R-HSA-5654736
MAPK family signaling cascades R-HSA-5683057
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by FGFR1 in disease R-HSA-5655302
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IGF1R signaling cascade R-HSA-2428924
Disease R-HSA-1643685
Signaling by FGFR in disease R-HSA-1226099
Insulin receptor signalling cascade R-HSA-74751
FGFR1c and Klotho ligand binding and activation R-HSA-190374
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Insulin receptor R-HSA-74752
Signaling by activated point mutants of FGFR1 R-HSA-1839122
PIP3 activates AKT signaling R-HSA-1257604
FRS-mediated FGFR1 signaling R-HSA-5654693
Intracellular signaling by second messengers R-HSA-9006925
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
SHC-mediated cascade:FGFR1 R-HSA-5654688
Axon guidance R-HSA-422475
IRS-mediated signalling R-HSA-112399
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
FGFR1c ligand binding and activation R-HSA-190373
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
L1CAM interactions R-HSA-373760
Signal transduction by L1 R-HSA-445144
PI3K Cascade R-HSA-109704
PI3K/AKT Signaling in Cancer R-HSA-2219528
Downstream signaling of activated FGFR1 R-HSA-5654687
PI-3K cascade:FGFR1 R-HSA-5654689
FGFR1 ligand binding and activation R-HSA-190242
Signaling by FGFR1 amplification mutants R-HSA-1839120
Negative regulation of FGFR1 signaling R-HSA-5654726
Developmental Biology R-HSA-1266738
FGFR1b ligand binding and activation R-HSA-190370
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by FGFR R-HSA-190236
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Negative regulation of the PI3K/AKT network R-HSA-199418
Gastrulation R-HSA-9758941
IRS-related events triggered by IGF1R R-HSA-2428928
FGFR1c ligand binding and activation R-HSA-190373
Disease R-HSA-1643685
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
RAF/MAP kinase cascade R-HSA-5673001
IRS-related events triggered by IGF1R R-HSA-2428928
IRS-mediated signalling R-HSA-112399
SHC-mediated cascade:FGFR1 R-HSA-5654688
Nervous system development R-HSA-9675108
PIP3 activates AKT signaling R-HSA-1257604
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR in disease R-HSA-1226099
Negative regulation of FGFR1 signaling R-HSA-5654726
Developmental Biology R-HSA-1266738
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR1 in disease R-HSA-5655302
PI3K/AKT Signaling in Cancer R-HSA-2219528
FGFR1b ligand binding and activation R-HSA-190370
IGF1R signaling cascade R-HSA-2428924
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FGFR1 ligand binding and activation R-HSA-190242
Insulin receptor signalling cascade R-HSA-74751
Negative regulation of the PI3K/AKT network R-HSA-199418
NCAM signaling for neurite out-growth R-HSA-375165
PI-3K cascade:FGFR1 R-HSA-5654689
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Gastrulation R-HSA-9758941
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by activated point mutants of FGFR1 R-HSA-1839122
Signal transduction by L1 R-HSA-445144
L1CAM interactions R-HSA-373760
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
FRS-mediated FGFR1 signaling R-HSA-5654693
FGFR1 mutant receptor activation R-HSA-1839124
Formation of paraxial mesoderm R-HSA-9793380
Signaling by FGFR R-HSA-190236
FGFR1c and Klotho ligand binding and activation R-HSA-190374
PI3K Cascade R-HSA-109704
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by FGFR1 amplification mutants R-HSA-1839120
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR1 R-HSA-5654736
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signaling of activated FGFR1 R-HSA-5654687
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
FGFR1c ligand binding and activation R-HSA-190373
IGF1R signaling cascade R-HSA-2428924
Nervous system development R-HSA-9675108
FGFR1 ligand binding and activation R-HSA-190242
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR R-HSA-190236
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Insulin receptor signalling cascade R-HSA-74751
L1CAM interactions R-HSA-373760
Intracellular signaling by second messengers R-HSA-9006925
Signaling by activated point mutants of FGFR1 R-HSA-1839122
PIP3 activates AKT signaling R-HSA-1257604
Signaling by FGFR1 in disease R-HSA-5655302
Signal transduction by L1 R-HSA-445144
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
Signaling by FGFR1 R-HSA-5654736
IRS-mediated signalling R-HSA-112399
Signaling by FGFR in disease R-HSA-1226099
NCAM signaling for neurite out-growth R-HSA-375165
IRS-related events triggered by IGF1R R-HSA-2428928
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
Developmental Biology R-HSA-1266738
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by FGFR1 amplification mutants R-HSA-1839120
Axon guidance R-HSA-422475
FGFR1c and Klotho ligand binding and activation R-HSA-190374
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Insulin receptor R-HSA-74752
Formation of paraxial mesoderm R-HSA-9793380
SHC-mediated cascade:FGFR1 R-HSA-5654688
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K Cascade R-HSA-109704
FRS-mediated FGFR1 signaling R-HSA-5654693
MAPK family signaling cascades R-HSA-5683057
Gastrulation R-HSA-9758941
RAF/MAP kinase cascade R-HSA-5673001
FGFR1b ligand binding and activation R-HSA-190370
Developmental Biology R-HSA-1266738
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR R-HSA-190236
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FGFR1 mutant receptor activation R-HSA-1839124
Signal Transduction R-HSA-162582
IRS-related events triggered by IGF1R R-HSA-2428928
Formation of paraxial mesoderm R-HSA-9793380
PI3K Cascade R-HSA-109704
Disease R-HSA-1643685
L1CAM interactions R-HSA-373760
Signal transduction by L1 R-HSA-445144
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by FGFR1 in disease R-HSA-5655302
MAPK family signaling cascades R-HSA-5683057
IRS-mediated signalling R-HSA-112399
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by activated point mutants of FGFR1 R-HSA-1839122
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Signaling by FGFR1 R-HSA-5654736
Signaling by FGFR1 amplification mutants R-HSA-1839120
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Signaling by Insulin receptor R-HSA-74752
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF/MAP kinase cascade R-HSA-5673001
SHC-mediated cascade:FGFR1 R-HSA-5654688
Axon guidance R-HSA-422475
IGF1R signaling cascade R-HSA-2428924
MAPK1/MAPK3 signaling R-HSA-5684996
Nervous system development R-HSA-9675108
Downstream signaling of activated FGFR1 R-HSA-5654687
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Gastrulation R-HSA-9758941
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
NCAM signaling for neurite out-growth R-HSA-375165
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
Insulin receptor signalling cascade R-HSA-74751
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
FGFR1b ligand binding and activation R-HSA-190370
FGFR1 ligand binding and activation R-HSA-190242
FGFR1c ligand binding and activation R-HSA-190373
Signaling by FGFR in disease R-HSA-1226099
FRS-mediated FGFR1 signaling R-HSA-5654693

Expression Atlas ENSG00000077782
LRG display in Ensembl gene LRG_993
NCBI gene (formerly Entrezgene) 2260
GeneCards 3688
HGNC Symbol HGNC:3688
MIM gene 136350
MIM morbid 615465
UniProtKB Gene Name P11362
WikiGene 2260
Gene: NTRK3
Ensembl ID : ENSG00000140538
Description: neurotrophic receptor tyrosine kinase 3
Gene Synonyms: TRKC
3 APIs:
271 Possible Orthologues:

Signaling by NTRKs R-HSA-166520
NTRK3 as a dependence receptor R-HSA-9603505
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through PI3K R-HSA-9603381
Neuronal System R-HSA-112316
Protein-protein interactions at synapses R-HSA-6794362
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTF3 activates NTRK3 signaling R-HSA-9034013
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Activated NTRK3 signals through RAS R-HSA-9034864
Signal Transduction R-HSA-162582
Activated NTRK3 signals through PI3K R-HSA-9603381
Activated NTRK3 signals through RAS R-HSA-9034864
Activated NTRK3 signals through PLCG1 R-HSA-9034793
NTRK3 as a dependence receptor R-HSA-9603505
Signal Transduction R-HSA-162582
Protein-protein interactions at synapses R-HSA-6794362
Signaling by NTRK3 (TRKC) R-HSA-9034015
NTF3 activates NTRK3 signaling R-HSA-9034013
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRKs R-HSA-166520
Neuronal System R-HSA-112316
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Signal Transduction R-HSA-162582
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by NTRKs R-HSA-166520
Activated NTRK3 signals through RAS R-HSA-9034864
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRK3 (TRKC) R-HSA-9034015
NTF3 activates NTRK3 signaling R-HSA-9034013
NTRK3 as a dependence receptor R-HSA-9603505
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Protein-protein interactions at synapses R-HSA-6794362
Neuronal System R-HSA-112316
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTF3 activates NTRK3 signaling R-HSA-9034013
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through RAS R-HSA-9034864
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Protein-protein interactions at synapses R-HSA-6794362
Signal Transduction R-HSA-162582
NTRK3 as a dependence receptor R-HSA-9603505
Neuronal System R-HSA-112316
Signaling by NTRKs R-HSA-166520
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Activated NTRK3 signals through PI3K R-HSA-9603381
Protein-protein interactions at synapses R-HSA-6794362
NTF3 activates NTRK3 signaling R-HSA-9034013
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activated NTRK3 signals through RAS R-HSA-9034864
Signaling by NTRKs R-HSA-166520
Signaling by NTRK3 (TRKC) R-HSA-9034015
NTRK3 as a dependence receptor R-HSA-9603505
Activated NTRK3 signals through PI3K R-HSA-9603381
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Signal Transduction R-HSA-162582
Neuronal System R-HSA-112316
Signaling by NTRKs R-HSA-166520
NTRK3 as a dependence receptor R-HSA-9603505
Signaling by NTRK3 (TRKC) R-HSA-9034015
Receptor-type tyrosine-protein phosphatases R-HSA-388844
NTF3 activates NTRK3 signaling R-HSA-9034013
Signal Transduction R-HSA-162582
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Protein-protein interactions at synapses R-HSA-6794362
Activated NTRK3 signals through RAS R-HSA-9034864
Neuronal System R-HSA-112316
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Protein-protein interactions at synapses R-HSA-6794362
Signaling by NTRKs R-HSA-166520
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTRK3 as a dependence receptor R-HSA-9603505
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through PI3K R-HSA-9603381
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Activated NTRK3 signals through RAS R-HSA-9034864
NTF3 activates NTRK3 signaling R-HSA-9034013
Signal Transduction R-HSA-162582
Neuronal System R-HSA-112316
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Neuronal System R-HSA-112316
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activated NTRK3 signals through RAS R-HSA-9034864
NTRK3 as a dependence receptor R-HSA-9603505
NTF3 activates NTRK3 signaling R-HSA-9034013
Signal Transduction R-HSA-162582
Protein-protein interactions at synapses R-HSA-6794362
Signaling by NTRKs R-HSA-166520
Signaling by NTRKs R-HSA-166520
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Neuronal System R-HSA-112316
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through RAS R-HSA-9034864
Protein-protein interactions at synapses R-HSA-6794362
Signal Transduction R-HSA-162582
NTRK3 as a dependence receptor R-HSA-9603505
Activated NTRK3 signals through PI3K R-HSA-9603381
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTF3 activates NTRK3 signaling R-HSA-9034013

Expression Atlas ENSG00000140538
NCBI gene (formerly Entrezgene) 4916
GeneCards 8033
HGNC Symbol HGNC:8033
MIM gene 191316
UniProtKB Gene Name X5DNW6
WikiGene 4916
Gene: KIF5B
Ensembl ID : ENSG00000170759
Description: kinesin family member 5B
Gene Synonyms: KNS,KNS1,UKHC
2 APIs:
288 Possible Orthologues:

Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Hemostasis R-HSA-109582
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
MHC class II antigen presentation R-HSA-2132295
Adaptive Immune System R-HSA-1280218
Factors involved in megakaryocyte development and platelet production R-HSA-983231
RHO GTPase Effectors R-HSA-195258
Metabolism of proteins R-HSA-392499
Membrane Trafficking R-HSA-199991
Kinesins R-HSA-983189
Vesicle-mediated transport R-HSA-5653656
Immune System R-HSA-168256
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Insulin processing R-HSA-264876
Peptide hormone metabolism R-HSA-2980736
RHO GTPases activate KTN1 R-HSA-5625970
Signaling by ALK in cancer R-HSA-9700206
Signaling by Rho GTPases R-HSA-194315
Golgi-to-ER retrograde transport R-HSA-8856688
Disease R-HSA-1643685
Hemostasis R-HSA-109582
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Signaling by ALK in cancer R-HSA-9700206
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Peptide hormone metabolism R-HSA-2980736
Disease R-HSA-1643685
Kinesins R-HSA-983189
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Signaling by Rho GTPases R-HSA-194315
Metabolism of proteins R-HSA-392499
Golgi-to-ER retrograde transport R-HSA-8856688
Vesicle-mediated transport R-HSA-5653656
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Membrane Trafficking R-HSA-199991
MHC class II antigen presentation R-HSA-2132295
Insulin processing R-HSA-264876
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPases activate KTN1 R-HSA-5625970
RHO GTPase Effectors R-HSA-195258
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Immune System R-HSA-168256
Signaling by Rho GTPases R-HSA-194315
RHO GTPase Effectors R-HSA-195258
RHO GTPases activate KTN1 R-HSA-5625970
Disease R-HSA-1643685
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
MHC class II antigen presentation R-HSA-2132295
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Membrane Trafficking R-HSA-199991
Signaling by ALK in cancer R-HSA-9700206
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Kinesins R-HSA-983189
Vesicle-mediated transport R-HSA-5653656
Golgi-to-ER retrograde transport R-HSA-8856688
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Insulin processing R-HSA-264876
Hemostasis R-HSA-109582
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Immune System R-HSA-168256
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Insulin processing R-HSA-264876
Disease R-HSA-1643685
MHC class II antigen presentation R-HSA-2132295
Golgi-to-ER retrograde transport R-HSA-8856688
Adaptive Immune System R-HSA-1280218
RHO GTPases activate KTN1 R-HSA-5625970
Hemostasis R-HSA-109582
Vesicle-mediated transport R-HSA-5653656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signal Transduction R-HSA-162582
Kinesins R-HSA-983189
Signaling by Rho GTPases R-HSA-194315
Metabolism of proteins R-HSA-392499
Signaling by ALK in cancer R-HSA-9700206
Membrane Trafficking R-HSA-199991
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RHO GTPase Effectors R-HSA-195258
Peptide hormone metabolism R-HSA-2980736
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Hemostasis R-HSA-109582
Kinesins R-HSA-983189
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signal Transduction R-HSA-162582
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Golgi-to-ER retrograde transport R-HSA-8856688
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
MHC class II antigen presentation R-HSA-2132295
Immune System R-HSA-168256
Metabolism of proteins R-HSA-392499
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Membrane Trafficking R-HSA-199991
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Insulin processing R-HSA-264876
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
Signaling by Rho GTPases R-HSA-194315
RHO GTPases activate KTN1 R-HSA-5625970
Vesicle-mediated transport R-HSA-5653656
Disease R-HSA-1643685
Peptide hormone metabolism R-HSA-2980736
Signaling by ALK in cancer R-HSA-9700206
RHO GTPase Effectors R-HSA-195258
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Membrane Trafficking R-HSA-199991
Adaptive Immune System R-HSA-1280218
RHO GTPase Effectors R-HSA-195258
Signaling by Rho GTPases R-HSA-194315
MHC class II antigen presentation R-HSA-2132295
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Peptide hormone metabolism R-HSA-2980736
Golgi-to-ER retrograde transport R-HSA-8856688
Signal Transduction R-HSA-162582
Vesicle-mediated transport R-HSA-5653656
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Insulin processing R-HSA-264876
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by ALK in cancer R-HSA-9700206
Kinesins R-HSA-983189
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Hemostasis R-HSA-109582
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK fusions and activated point mutants R-HSA-9725370
RHO GTPases activate KTN1 R-HSA-5625970
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Insulin processing R-HSA-264876
Signal Transduction R-HSA-162582
Membrane Trafficking R-HSA-199991
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Adaptive Immune System R-HSA-1280218
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Kinesins R-HSA-983189
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signaling by ALK in cancer R-HSA-9700206
Golgi-to-ER retrograde transport R-HSA-8856688
MHC class II antigen presentation R-HSA-2132295
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Hemostasis R-HSA-109582
RHO GTPase Effectors R-HSA-195258
Immune System R-HSA-168256
Signaling by Rho GTPases R-HSA-194315
Vesicle-mediated transport R-HSA-5653656
RHO GTPases activate KTN1 R-HSA-5625970
Disease R-HSA-1643685
Hemostasis R-HSA-109582
Kinesins R-HSA-983189
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MHC class II antigen presentation R-HSA-2132295
Metabolism of proteins R-HSA-392499
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Signal Transduction R-HSA-162582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Insulin processing R-HSA-264876
Membrane Trafficking R-HSA-199991
RHO GTPase Effectors R-HSA-195258
Peptide hormone metabolism R-HSA-2980736
Signaling by Rho GTPases R-HSA-194315
RHO GTPases activate KTN1 R-HSA-5625970
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Golgi-to-ER retrograde transport R-HSA-8856688
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Immune System R-HSA-168256
Signaling by ALK in cancer R-HSA-9700206
Disease R-HSA-1643685
Vesicle-mediated transport R-HSA-5653656
Adaptive Immune System R-HSA-1280218
Golgi-to-ER retrograde transport R-HSA-8856688
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Peptide hormone metabolism R-HSA-2980736
Disease R-HSA-1643685
RHO GTPase Effectors R-HSA-195258
Adaptive Immune System R-HSA-1280218
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Kinesins R-HSA-983189
Membrane Trafficking R-HSA-199991
Immune System R-HSA-168256
Vesicle-mediated transport R-HSA-5653656
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Hemostasis R-HSA-109582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Signaling by ALK in cancer R-HSA-9700206
Insulin processing R-HSA-264876
Signal Transduction R-HSA-162582
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases R-HSA-194315
Metabolism of proteins R-HSA-392499
MHC class II antigen presentation R-HSA-2132295
RHO GTPases activate KTN1 R-HSA-5625970
Adaptive Immune System R-HSA-1280218
Peptide hormone metabolism R-HSA-2980736
Insulin processing R-HSA-264876
Signal Transduction R-HSA-162582
Kinesins R-HSA-983189
MHC class II antigen presentation R-HSA-2132295
RHO GTPase Effectors R-HSA-195258
Signaling by ALK in cancer R-HSA-9700206
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Disease R-HSA-1643685
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signaling by Rho GTPases R-HSA-194315
Immune System R-HSA-168256
RHO GTPases activate KTN1 R-HSA-5625970
Golgi-to-ER retrograde transport R-HSA-8856688
Vesicle-mediated transport R-HSA-5653656
Metabolism of proteins R-HSA-392499
Hemostasis R-HSA-109582
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Membrane Trafficking R-HSA-199991
Vesicle-mediated transport R-HSA-5653656
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Membrane Trafficking R-HSA-199991
Peptide hormone metabolism R-HSA-2980736
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Signaling by Rho GTPases R-HSA-194315
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Kinesins R-HSA-983189
RHO GTPase Effectors R-HSA-195258
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Disease R-HSA-1643685
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Insulin processing R-HSA-264876
RHO GTPases activate KTN1 R-HSA-5625970
Hemostasis R-HSA-109582
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
Golgi-to-ER retrograde transport R-HSA-8856688
MHC class II antigen presentation R-HSA-2132295
Signaling by ALK in cancer R-HSA-9700206

Expression Atlas ENSG00000170759
NCBI gene (formerly Entrezgene) 3799
GeneCards 6324
HGNC Symbol HGNC:6324
MIM gene 602809
UniProtKB Gene Name V9HW29
WikiGene 3799
Gene: JAK2
Ensembl ID : ENSG00000096968
Description: Janus kinase 2
Gene Synonyms: JTK10
23 APIs:
265 Possible Orthologues:

G1 Phase R-HSA-69236
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-2 family signaling R-HSA-451927
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Interleukin-6 signaling R-HSA-1059683
Interleukin-6 family signaling R-HSA-6783589
Mitotic G1 phase and G1/S transition R-HSA-453279
Chromatin organization R-HSA-4839726
Erythropoietin activates RAS R-HSA-9027284
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Infectious disease R-HSA-5663205
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV Infections R-HSA-9679506
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-23 signaling R-HSA-9020933
Signaling by KIT in disease R-HSA-9669938
RAF activation R-HSA-5673000
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
G1 Phase R-HSA-69236
Interferon gamma signaling R-HSA-877300
Interleukin-12 signaling R-HSA-9020591
Interleukin-35 Signalling R-HSA-8984722
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Growth hormone receptor signaling R-HSA-982772
Cyclin D associated events in G1 R-HSA-69231
Interleukin-12 family signaling R-HSA-447115
MAPK family signaling cascades R-HSA-5683057
Signaling by Erythropoietin R-HSA-9006335
Prolactin receptor signaling R-HSA-1170546
Interleukin-27 signaling R-HSA-9020956
Disease R-HSA-1643685
Hemostasis R-HSA-109582
RMTs methylate histone arginines R-HSA-3214858
Potential therapeutics for SARS R-HSA-9679191
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Erythropoietin activates STAT5 R-HSA-9027283
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-20 family signaling R-HSA-8854691
Signaling by Leptin R-HSA-2586552
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK1 (ERK2) activation R-HSA-112411
Signaling by SCF-KIT R-HSA-1433557
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Oncogenic MAPK signaling R-HSA-6802957
Signaling by RAS mutants R-HSA-6802949
Immune System R-HSA-168256
Interferon Signaling R-HSA-913531
Signaling by Interleukins R-HSA-449147
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Chromatin modifying enzymes R-HSA-3247509
Regulation of IFNG signaling R-HSA-877312
Signaling by RAF1 mutants R-HSA-9656223
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Cell Cycle R-HSA-1640170
Interleukin receptor SHC signaling R-HSA-912526
Interleukin-2 family signaling R-HSA-451927
Signaling by Leptin R-HSA-2586552
Interleukin-6 family signaling R-HSA-6783589
Cell Cycle R-HSA-1640170
Signal Transduction R-HSA-162582
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Chromatin modifying enzymes R-HSA-3247509
Interleukin-12 family signaling R-HSA-447115
Growth hormone receptor signaling R-HSA-982772
Potential therapeutics for SARS R-HSA-9679191
Erythropoietin activates RAS R-HSA-9027284
Interferon Signaling R-HSA-913531
Interleukin-27 signaling R-HSA-9020956
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Interleukin-12 signaling R-HSA-9020591
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-23 signaling R-HSA-9020933
Interferon gamma signaling R-HSA-877300
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Regulation of IFNG signaling R-HSA-877312
Disease R-HSA-1643685
Interleukin-20 family signaling R-HSA-8854691
RAF-independent MAPK1/3 activation R-HSA-112409
Cyclin D associated events in G1 R-HSA-69231
Signaling by Erythropoietin R-HSA-9006335
Erythropoietin activates STAT5 R-HSA-9027283
MAPK family signaling cascades R-HSA-5683057
Signaling by RAF1 mutants R-HSA-9656223
Cytokine Signaling in Immune system R-HSA-1280215
Chromatin organization R-HSA-4839726
RMTs methylate histone arginines R-HSA-3214858
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
G1 Phase R-HSA-69236
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Interleukin-35 Signalling R-HSA-8984722
Factors involved in megakaryocyte development and platelet production R-HSA-983231
MAPK3 (ERK1) activation R-HSA-110056
Infectious disease R-HSA-5663205
MAPK1 (ERK2) activation R-HSA-112411
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Prolactin receptor signaling R-HSA-1170546
Mitotic G1 phase and G1/S transition R-HSA-453279
Oncogenic MAPK signaling R-HSA-6802957
Interleukin-6 signaling R-HSA-1059683
Signaling by RAS mutants R-HSA-6802949
Interleukin receptor SHC signaling R-HSA-912526
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
RAF activation R-HSA-5673000
Signaling downstream of RAS mutants R-HSA-9649948
Cell Cycle, Mitotic R-HSA-69278
Signaling by KIT in disease R-HSA-9669938
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hemostasis R-HSA-109582
Signaling by CSF3 (G-CSF) R-HSA-9674555
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
SARS-CoV Infections R-HSA-9679506
RAF/MAP kinase cascade R-HSA-5673001
Chromatin modifying enzymes R-HSA-3247509
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Cell Cycle R-HSA-1640170
Interleukin-12 family signaling R-HSA-447115
Interleukin-35 Signalling R-HSA-8984722
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Interleukin-6 signaling R-HSA-1059683
Immune System R-HSA-168256
Interleukin receptor SHC signaling R-HSA-912526
G1 Phase R-HSA-69236
Growth hormone receptor signaling R-HSA-982772
Interferon Signaling R-HSA-913531
Signaling by Erythropoietin R-HSA-9006335
RAF activation R-HSA-5673000
Erythropoietin activates STAT5 R-HSA-9027283
Erythropoietin activates RAS R-HSA-9027284
Interferon gamma signaling R-HSA-877300
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-20 family signaling R-HSA-8854691
Interleukin-6 family signaling R-HSA-6783589
Interleukin-27 signaling R-HSA-9020956
Infectious disease R-HSA-5663205
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of IFNG signaling R-HSA-877312
Potential therapeutics for SARS R-HSA-9679191
Prolactin receptor signaling R-HSA-1170546
MAPK3 (ERK1) activation R-HSA-110056
Signaling by SCF-KIT R-HSA-1433557
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Disease R-HSA-1643685
Interleukin-23 signaling R-HSA-9020933
Signal Transduction R-HSA-162582
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Signaling by RAS mutants R-HSA-6802949
Cell Cycle, Mitotic R-HSA-69278
Cytokine Signaling in Immune system R-HSA-1280215
SARS-CoV Infections R-HSA-9679506
MAPK family signaling cascades R-HSA-5683057
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Cyclin D associated events in G1 R-HSA-69231
RMTs methylate histone arginines R-HSA-3214858
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Interleukins R-HSA-449147
Signaling by KIT in disease R-HSA-9669938
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Oncogenic MAPK signaling R-HSA-6802957
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-12 signaling R-HSA-9020591
Signaling by Leptin R-HSA-2586552
Chromatin organization R-HSA-4839726
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-2 family signaling R-HSA-451927
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK1 (ERK2) activation R-HSA-112411
Hemostasis R-HSA-109582
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-23 signaling R-HSA-9020933
Signaling downstream of RAS mutants R-HSA-9649948
Potential therapeutics for SARS R-HSA-9679191
Interleukin-2 family signaling R-HSA-451927
Erythropoietin activates STAT5 R-HSA-9027283
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Prolactin receptor signaling R-HSA-1170546
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RMTs methylate histone arginines R-HSA-3214858
MAPK1 (ERK2) activation R-HSA-112411
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Interferon gamma signaling R-HSA-877300
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-20 family signaling R-HSA-8854691
Cell Cycle R-HSA-1640170
Hemostasis R-HSA-109582
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Interleukin-35 Signalling R-HSA-8984722
Cell Cycle, Mitotic R-HSA-69278
Signal Transduction R-HSA-162582
Chromatin modifying enzymes R-HSA-3247509
Disease R-HSA-1643685
Signaling by CSF3 (G-CSF) R-HSA-9674555
G1 Phase R-HSA-69236
Cyclin D associated events in G1 R-HSA-69231
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
Signaling by RAS mutants R-HSA-6802949
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Chromatin organization R-HSA-4839726
MAPK3 (ERK1) activation R-HSA-110056
Signaling by KIT in disease R-HSA-9669938
Interferon Signaling R-HSA-913531
Signaling by SCF-KIT R-HSA-1433557
MAPK family signaling cascades R-HSA-5683057
Interleukin-6 signaling R-HSA-1059683
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by BRAF and RAF1 fusions R-HSA-6802952
RAF-independent MAPK1/3 activation R-HSA-112409
Erythropoietin activates RAS R-HSA-9027284
Signaling by RAF1 mutants R-HSA-9656223
RAF activation R-HSA-5673000
Factors involved in megakaryocyte development and platelet production R-HSA-983231
SARS-CoV Infections R-HSA-9679506
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Regulation of IFNG signaling R-HSA-877312
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Oncogenic MAPK signaling R-HSA-6802957
Immune System R-HSA-168256
Signaling by Leptin R-HSA-2586552
Interleukin-12 family signaling R-HSA-447115
Interleukin-27 signaling R-HSA-9020956
Interleukin receptor SHC signaling R-HSA-912526
Mitotic G1 phase and G1/S transition R-HSA-453279
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-6 family signaling R-HSA-6783589
Signaling by Erythropoietin R-HSA-9006335
Interleukin-12 signaling R-HSA-9020591
Growth hormone receptor signaling R-HSA-982772
Interleukin-20 family signaling R-HSA-8854691
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Immune System R-HSA-168256
Regulation of IFNG signaling R-HSA-877312
Chromatin modifying enzymes R-HSA-3247509
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Chromatin organization R-HSA-4839726
Erythropoietin activates STAT5 R-HSA-9027283
Potential therapeutics for SARS R-HSA-9679191
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
SARS-CoV Infections R-HSA-9679506
Oncogenic MAPK signaling R-HSA-6802957
G1 Phase R-HSA-69236
Interleukin-12 family signaling R-HSA-447115
Cyclin D associated events in G1 R-HSA-69231
Interleukin-27 signaling R-HSA-9020956
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Erythropoietin activates RAS R-HSA-9027284
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Interleukin-6 signaling R-HSA-1059683
Signaling by Interleukins R-HSA-449147
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Hemostasis R-HSA-109582
Signaling by RAF1 mutants R-HSA-9656223
Cell Cycle R-HSA-1640170
Mitotic G1 phase and G1/S transition R-HSA-453279
Factors involved in megakaryocyte development and platelet production R-HSA-983231
RAF-independent MAPK1/3 activation R-HSA-112409
Growth hormone receptor signaling R-HSA-982772
Signaling by KIT in disease R-HSA-9669938
Cytokine Signaling in Immune system R-HSA-1280215
MAPK1 (ERK2) activation R-HSA-112411
RMTs methylate histone arginines R-HSA-3214858
Cell Cycle, Mitotic R-HSA-69278
Interferon gamma signaling R-HSA-877300
Signaling by Erythropoietin R-HSA-9006335
Prolactin receptor signaling R-HSA-1170546
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-35 Signalling R-HSA-8984722
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Interleukin receptor SHC signaling R-HSA-912526
Interferon Signaling R-HSA-913531
Signaling by RAS mutants R-HSA-6802949
Interleukin-2 family signaling R-HSA-451927
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-6 family signaling R-HSA-6783589
Disease R-HSA-1643685
MAPK family signaling cascades R-HSA-5683057
RAF activation R-HSA-5673000
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Signaling by BRAF and RAF1 fusions R-HSA-6802952
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling downstream of RAS mutants R-HSA-9649948
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Signaling by SCF-KIT R-HSA-1433557
Interleukin-12 signaling R-HSA-9020591
Signaling by Leptin R-HSA-2586552
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Infectious disease R-HSA-5663205
Interleukin-23 signaling R-HSA-9020933
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Leptin R-HSA-2586552
Hemostasis R-HSA-109582
Regulation of IFNG signaling R-HSA-877312
Growth hormone receptor signaling R-HSA-982772
RAF activation R-HSA-5673000
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Interferon Signaling R-HSA-913531
Prolactin receptor signaling R-HSA-1170546
Cell Cycle R-HSA-1640170
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by RAS mutants R-HSA-6802949
Signaling by KIT in disease R-HSA-9669938
Signaling by Interleukins R-HSA-449147
Cyclin D associated events in G1 R-HSA-69231
RMTs methylate histone arginines R-HSA-3214858
Interleukin-2 family signaling R-HSA-451927
SARS-CoV Infections R-HSA-9679506
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Erythropoietin R-HSA-9006335
Disease R-HSA-1643685
Erythropoietin activates STAT5 R-HSA-9027283
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Chromatin modifying enzymes R-HSA-3247509
Erythropoietin activates RAS R-HSA-9027284
Interleukin-12 family signaling R-HSA-447115
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-6 family signaling R-HSA-6783589
Infectious disease R-HSA-5663205
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Interleukin receptor SHC signaling R-HSA-912526
Signaling by BRAF and RAF1 fusions R-HSA-6802952
G1 Phase R-HSA-69236
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-23 signaling R-HSA-9020933
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
MAPK1 (ERK2) activation R-HSA-112411
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-12 signaling R-HSA-9020591
Interleukin-6 signaling R-HSA-1059683
Chromatin organization R-HSA-4839726
Immune System R-HSA-168256
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle, Mitotic R-HSA-69278
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Interleukin-27 signaling R-HSA-9020956
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Potential therapeutics for SARS R-HSA-9679191
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Signaling by CSF3 (G-CSF) R-HSA-9674555
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-20 family signaling R-HSA-8854691
Interleukin-35 Signalling R-HSA-8984722
Signaling by SCF-KIT R-HSA-1433557
Oncogenic MAPK signaling R-HSA-6802957
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
MAPK1/MAPK3 signaling R-HSA-5684996
Interferon gamma signaling R-HSA-877300
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signaling by RAF1 mutants R-HSA-9656223
Signal Transduction R-HSA-162582
Interleukin-6 family signaling R-HSA-6783589
Cell Cycle, Mitotic R-HSA-69278
Interleukin-6 signaling R-HSA-1059683
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin receptor SHC signaling R-HSA-912526
Interleukin-23 signaling R-HSA-9020933
Signaling by Leptin R-HSA-2586552
Cyclin D associated events in G1 R-HSA-69231
RAF-independent MAPK1/3 activation R-HSA-112409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-12 signaling R-HSA-9020591
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Cytokine Signaling in Immune system R-HSA-1280215
Chromatin modifying enzymes R-HSA-3247509
Oncogenic MAPK signaling R-HSA-6802957
MAPK1 (ERK2) activation R-HSA-112411
Interleukin-20 family signaling R-HSA-8854691
Signaling by Erythropoietin R-HSA-9006335
Interferon gamma signaling R-HSA-877300
Hemostasis R-HSA-109582
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Interleukin-2 family signaling R-HSA-451927
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Erythropoietin activates RAS R-HSA-9027284
Prolactin receptor signaling R-HSA-1170546
Regulation of IFNG signaling R-HSA-877312
Interleukin-27 signaling R-HSA-9020956
RAF/MAP kinase cascade R-HSA-5673001
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Growth hormone receptor signaling R-HSA-982772
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by KIT in disease R-HSA-9669938
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
SARS-CoV Infections R-HSA-9679506
RMTs methylate histone arginines R-HSA-3214858
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Chromatin organization R-HSA-4839726
Signaling by RAS mutants R-HSA-6802949
Infectious disease R-HSA-5663205
Interferon Signaling R-HSA-913531
Interleukin-12 family signaling R-HSA-447115
Potential therapeutics for SARS R-HSA-9679191
Mitotic G1 phase and G1/S transition R-HSA-453279
Erythropoietin activates STAT5 R-HSA-9027283
MAPK family signaling cascades R-HSA-5683057
Cell Cycle R-HSA-1640170
Interleukin-35 Signalling R-HSA-8984722
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
MAPK3 (ERK1) activation R-HSA-110056
RAF activation R-HSA-5673000
G1 Phase R-HSA-69236
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Disease R-HSA-1643685
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Infectious disease R-HSA-5663205
Cell Cycle, Mitotic R-HSA-69278
Interferon Signaling R-HSA-913531
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-23 signaling R-HSA-9020933
G1 Phase R-HSA-69236
Potential therapeutics for SARS R-HSA-9679191
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-12 family signaling R-HSA-447115
Signaling by KIT in disease R-HSA-9669938
Disease R-HSA-1643685
Interleukin-12 signaling R-HSA-9020591
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signal Transduction R-HSA-162582
Interleukin-35 Signalling R-HSA-8984722
Chromatin organization R-HSA-4839726
Cyclin D associated events in G1 R-HSA-69231
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Signaling by RAF1 mutants R-HSA-9656223
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Oncogenic MAPK signaling R-HSA-6802957
Interleukin receptor SHC signaling R-HSA-912526
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
RMTs methylate histone arginines R-HSA-3214858
Chromatin modifying enzymes R-HSA-3247509
MAPK3 (ERK1) activation R-HSA-110056
RAF activation R-HSA-5673000
Signaling by Interleukins R-HSA-449147
Cell Cycle R-HSA-1640170
Signaling by Erythropoietin R-HSA-9006335
Hemostasis R-HSA-109582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by CSF3 (G-CSF) R-HSA-9674555
Growth hormone receptor signaling R-HSA-982772
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Interleukin-20 family signaling R-HSA-8854691
Mitotic G1 phase and G1/S transition R-HSA-453279
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of IFNG signaling R-HSA-877312
Prolactin receptor signaling R-HSA-1170546
MAPK1 (ERK2) activation R-HSA-112411
Interleukin-27 signaling R-HSA-9020956
MAPK family signaling cascades R-HSA-5683057
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
RAF-independent MAPK1/3 activation R-HSA-112409
RAF/MAP kinase cascade R-HSA-5673001
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Interleukin-6 family signaling R-HSA-6783589
Interleukin-6 signaling R-HSA-1059683
SARS-CoV Infections R-HSA-9679506
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Interleukin-2 family signaling R-HSA-451927
MAPK1/MAPK3 signaling R-HSA-5684996
Interferon gamma signaling R-HSA-877300
Signaling by SCF-KIT R-HSA-1433557
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Immune System R-HSA-168256
Erythropoietin activates RAS R-HSA-9027284
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by RAS mutants R-HSA-6802949
Signaling by Leptin R-HSA-2586552
Erythropoietin activates STAT5 R-HSA-9027283
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Growth hormone receptor signaling R-HSA-982772
Signaling by KIT in disease R-HSA-9669938
Interleukin-20 family signaling R-HSA-8854691
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Disease R-HSA-1643685
Interleukin-6 family signaling R-HSA-6783589
Interleukin-2 family signaling R-HSA-451927
Interleukin-12 signaling R-HSA-9020591
Interleukin-6 signaling R-HSA-1059683
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Interleukin receptor SHC signaling R-HSA-912526
Erythropoietin activates STAT5 R-HSA-9027283
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Chromatin organization R-HSA-4839726
Signal Transduction R-HSA-162582
G1 Phase R-HSA-69236
Interleukin-27 signaling R-HSA-9020956
Prolactin receptor signaling R-HSA-1170546
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-12 family signaling R-HSA-447115
Signaling by Interleukins R-HSA-449147
Signaling downstream of RAS mutants R-HSA-9649948
Immune System R-HSA-168256
MAPK1 (ERK2) activation R-HSA-112411
Cell Cycle R-HSA-1640170
Signaling by Erythropoietin R-HSA-9006335
RMTs methylate histone arginines R-HSA-3214858
Interleukin-23 signaling R-HSA-9020933
Infectious disease R-HSA-5663205
RAF activation R-HSA-5673000
Signaling by Leptin R-HSA-2586552
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Hemostasis R-HSA-109582
Interferon gamma signaling R-HSA-877300
Interleukin-35 Signalling R-HSA-8984722
MAPK1/MAPK3 signaling R-HSA-5684996
Cyclin D associated events in G1 R-HSA-69231
Signaling by RAS mutants R-HSA-6802949
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
Potential therapeutics for SARS R-HSA-9679191
MAPK family signaling cascades R-HSA-5683057
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Regulation of IFNG signaling R-HSA-877312
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
SARS-CoV Infections R-HSA-9679506
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Interferon Signaling R-HSA-913531
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK3 (ERK1) activation R-HSA-110056
Erythropoietin activates RAS R-HSA-9027284
Signaling by RAF1 mutants R-HSA-9656223
Chromatin modifying enzymes R-HSA-3247509
Oncogenic MAPK signaling R-HSA-6802957
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by SCF-KIT R-HSA-1433557
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Interleukin-6 signaling R-HSA-1059683
Chromatin organization R-HSA-4839726
Signaling by KIT in disease R-HSA-9669938
Interleukin-23 signaling R-HSA-9020933
RAF activation R-HSA-5673000
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Mitotic G1 phase and G1/S transition R-HSA-453279
MAPK1 (ERK2) activation R-HSA-112411
Interferon Signaling R-HSA-913531
Signaling by RAS mutants R-HSA-6802949
Interferon gamma signaling R-HSA-877300
Infectious disease R-HSA-5663205
MAPK1/MAPK3 signaling R-HSA-5684996
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
RAF-independent MAPK1/3 activation R-HSA-112409
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Interleukin-2 family signaling R-HSA-451927
Interleukin-35 Signalling R-HSA-8984722
Interleukin-12 signaling R-HSA-9020591
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Potential therapeutics for SARS R-HSA-9679191
Signaling by Interleukins R-HSA-449147
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Prolactin receptor signaling R-HSA-1170546
Regulation of IFNG signaling R-HSA-877312
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Signaling by Leptin R-HSA-2586552
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Interleukin-12 family signaling R-HSA-447115
Erythropoietin activates STAT5 R-HSA-9027283
Signaling downstream of RAS mutants R-HSA-9649948
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Hemostasis R-HSA-109582
Interleukin-20 family signaling R-HSA-8854691
Signaling by RAF1 mutants R-HSA-9656223
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cyclin D associated events in G1 R-HSA-69231
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by CSF3 (G-CSF) R-HSA-9674555
Disease R-HSA-1643685
Interleukin-27 signaling R-HSA-9020956
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
Growth hormone receptor signaling R-HSA-982772
RMTs methylate histone arginines R-HSA-3214858
SARS-CoV Infections R-HSA-9679506
Interleukin receptor SHC signaling R-HSA-912526
Oncogenic MAPK signaling R-HSA-6802957
Cell Cycle R-HSA-1640170
Chromatin modifying enzymes R-HSA-3247509
Signaling by SCF-KIT R-HSA-1433557
Interleukin-6 family signaling R-HSA-6783589
Erythropoietin activates RAS R-HSA-9027284
Immune System R-HSA-168256
Signaling by Erythropoietin R-HSA-9006335

Expression Atlas ENSG00000096968
LRG display in Ensembl gene LRG_612
NCBI gene (formerly Entrezgene) 3717
GeneCards 6192
HGNC Symbol HGNC:6192
MIM gene 147796
MIM morbid 614521
UniProtKB Gene Name O60674
WikiGene 3717
Gene: IKBKB
Ensembl ID : ENSG00000104365
Description: inhibitor of nuclear factor kappa B kinase subunit beta
Gene Synonyms: IKK-BETA,IKK2,IKKB,NFKBIKB
7 APIs:
197 Possible Orthologues:

Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Diseases of Immune System R-HSA-5260271
TCR signaling R-HSA-202403
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
p75NTR recruits signalling complexes R-HSA-209543
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Diseases associated with the TLR signaling cascade R-HSA-5602358
Regulation of NF-kappa B signaling R-HSA-9758274
C-type lectin receptors (CLRs) R-HSA-5621481
TRAF6 mediated NF-kB activation R-HSA-933542
MyD88 cascade initiated on plasma membrane R-HSA-975871
p75NTR signals via NF-kB R-HSA-193639
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Signaling by the B Cell Receptor (BCR) R-HSA-983705
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
ER-Phagosome pathway R-HSA-1236974
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88 dependent cascade initiated on endosome R-HSA-975155
NOD1/2 Signaling Pathway R-HSA-168638
p75 NTR receptor-mediated signalling R-HSA-193704
IkBA variant leads to EDA-ID R-HSA-5603029
Activation of NF-kappaB in B cells R-HSA-1169091
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
MAP kinase activation R-HSA-450294
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
MyD88-independent TLR4 cascade R-HSA-166166
FCERI mediated NF-kB activation R-HSA-2871837
IKBKB deficiency causes SCID R-HSA-5602636
Immune System R-HSA-168256
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Interleukin-1 family signaling R-HSA-446652
SARS-CoV Infections R-HSA-9679506
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by Interleukins R-HSA-449147
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TNF signaling R-HSA-75893
CLEC7A (Dectin-1) signaling R-HSA-5607764
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
SARS-CoV-2 Infection R-HSA-9694516
NF-kB is activated and signals survival R-HSA-209560
Innate Immune System R-HSA-168249
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-1 signaling R-HSA-9020702
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Antigen processing-Cross presentation R-HSA-1236975
Downstream TCR signaling R-HSA-202424
Signal Transduction R-HSA-162582
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Toll-like Receptor Cascades R-HSA-168898
IKK complex recruitment mediated by RIP1 R-HSA-937041
Disease R-HSA-1643685
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
SARS-CoV-2-host interactions R-HSA-9705683
Cytokine Signaling in Immune system R-HSA-1280215
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
IRAK1 recruits IKK complex R-HSA-937039
Regulation of TNFR1 signaling R-HSA-5357905
MyD88 cascade initiated on plasma membrane R-HSA-975871
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
MyD88 dependent cascade initiated on endosome R-HSA-975155
IKK complex recruitment mediated by RIP1 R-HSA-937041
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
Interleukin-1 family signaling R-HSA-446652
Infectious disease R-HSA-5663205
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signal Transduction R-HSA-162582
ER-Phagosome pathway R-HSA-1236974
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of TNFR1 signaling R-HSA-5357905
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
IKBKB deficiency causes SCID R-HSA-5602636
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Interleukins R-HSA-449147
TRAF6 mediated NF-kB activation R-HSA-933542
MAP kinase activation R-HSA-450294
Innate Immune System R-HSA-168249
Interleukin-17 signaling R-HSA-448424
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MyD88-independent TLR4 cascade R-HSA-166166
C-type lectin receptors (CLRs) R-HSA-5621481
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
IkBA variant leads to EDA-ID R-HSA-5603029
Death Receptor Signaling R-HSA-73887
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
SARS-CoV Infections R-HSA-9679506
NF-kB is activated and signals survival R-HSA-209560
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
IRAK1 recruits IKK complex R-HSA-937039
p75NTR recruits signalling complexes R-HSA-209543
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Diseases of Immune System R-HSA-5260271
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
NOD1/2 Signaling Pathway R-HSA-168638
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Immune System R-HSA-168256
SARS-CoV-2 Infection R-HSA-9694516
TCR signaling R-HSA-202403
Activation of NF-kappaB in B cells R-HSA-1169091
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Diseases associated with the TLR signaling cascade R-HSA-5602358
Disease R-HSA-1643685
p75NTR signals via NF-kB R-HSA-193639
TNF signaling R-HSA-75893
Antigen processing-Cross presentation R-HSA-1236975
Downstream TCR signaling R-HSA-202424
SARS-CoV-2-host interactions R-HSA-9705683
Regulation of NF-kappa B signaling R-HSA-9758274
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
FCERI mediated NF-kB activation R-HSA-2871837
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
p75 NTR receptor-mediated signalling R-HSA-193704
Interleukin-1 signaling R-HSA-9020702
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
Toll-like Receptor Cascades R-HSA-168898
Immune System R-HSA-168256
Downstream TCR signaling R-HSA-202424
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Interleukin-1 family signaling R-HSA-446652
MyD88 dependent cascade initiated on endosome R-HSA-975155
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
NOD1/2 Signaling Pathway R-HSA-168638
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MAP kinase activation R-HSA-450294
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by Interleukins R-HSA-449147
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
FCERI mediated NF-kB activation R-HSA-2871837
C-type lectin receptors (CLRs) R-HSA-5621481
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
SARS-CoV Infections R-HSA-9679506
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Diseases associated with the TLR signaling cascade R-HSA-5602358
MyD88 cascade initiated on plasma membrane R-HSA-975871
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
TCR signaling R-HSA-202403
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
IkBA variant leads to EDA-ID R-HSA-5603029
p75NTR signals via NF-kB R-HSA-193639
p75 NTR receptor-mediated signalling R-HSA-193704
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
Diseases of Immune System R-HSA-5260271
IRAK1 recruits IKK complex R-HSA-937039
Activation of NF-kappaB in B cells R-HSA-1169091
ER-Phagosome pathway R-HSA-1236974
SARS-CoV-2 Infection R-HSA-9694516
TRAF6 mediated NF-kB activation R-HSA-933542
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Regulation of TNFR1 signaling R-HSA-5357905
Interleukin-17 signaling R-HSA-448424
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
NF-kB is activated and signals survival R-HSA-209560
MyD88-independent TLR4 cascade R-HSA-166166
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
IKBKB deficiency causes SCID R-HSA-5602636
Cytokine Signaling in Immune system R-HSA-1280215
TNF signaling R-HSA-75893
Signal Transduction R-HSA-162582
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Antigen processing-Cross presentation R-HSA-1236975
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Class I MHC mediated antigen processing & presentation R-HSA-983169
p75NTR recruits signalling complexes R-HSA-209543
SARS-CoV-2-host interactions R-HSA-9705683
IKK complex recruitment mediated by RIP1 R-HSA-937041
SARS-CoV-2 Infection R-HSA-9694516
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
SARS-CoV-2-host interactions R-HSA-9705683
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Disease R-HSA-1643685
IKBKB deficiency causes SCID R-HSA-5602636
p75 NTR receptor-mediated signalling R-HSA-193704
MyD88 cascade initiated on plasma membrane R-HSA-975871
p75NTR signals via NF-kB R-HSA-193639
Diseases of Immune System R-HSA-5260271
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p75NTR recruits signalling complexes R-HSA-209543
TNF signaling R-HSA-75893
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
SARS-CoV Infections R-HSA-9679506
Interleukin-1 family signaling R-HSA-446652
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
MAP kinase activation R-HSA-450294
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Antigen processing-Cross presentation R-HSA-1236975
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
C-type lectin receptors (CLRs) R-HSA-5621481
TRAF6 mediated NF-kB activation R-HSA-933542
Downstream TCR signaling R-HSA-202424
MyD88 dependent cascade initiated on endosome R-HSA-975155
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Class I MHC mediated antigen processing & presentation R-HSA-983169
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
ER-Phagosome pathway R-HSA-1236974
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
FCERI mediated NF-kB activation R-HSA-2871837
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Adaptive Immune System R-HSA-1280218
Diseases associated with the TLR signaling cascade R-HSA-5602358
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
NOD1/2 Signaling Pathway R-HSA-168638
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Infectious disease R-HSA-5663205
IRAK1 recruits IKK complex R-HSA-937039
TCR signaling R-HSA-202403
Activation of NF-kappaB in B cells R-HSA-1169091
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Regulation of TNFR1 signaling R-HSA-5357905
Signaling by Interleukins R-HSA-449147
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll-like Receptor Cascades R-HSA-168898
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
NF-kB is activated and signals survival R-HSA-209560
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88-independent TLR4 cascade R-HSA-166166
IKK complex recruitment mediated by RIP1 R-HSA-937041
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
IkBA variant leads to EDA-ID R-HSA-5603029
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Interleukin-1 signaling R-HSA-9020702
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Adaptive Immune System R-HSA-1280218
TNF signaling R-HSA-75893
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
IKBKB deficiency causes SCID R-HSA-5602636
Immune System R-HSA-168256
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
TRAF6 mediated NF-kB activation R-HSA-933542
Regulation of TNFR1 signaling R-HSA-5357905
Antigen processing-Cross presentation R-HSA-1236975
SARS-CoV-2 Infection R-HSA-9694516
MyD88 dependent cascade initiated on endosome R-HSA-975155
Class I MHC mediated antigen processing & presentation R-HSA-983169
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Diseases associated with the TLR signaling cascade R-HSA-5602358
Toll-like Receptor Cascades R-HSA-168898
FCERI mediated NF-kB activation R-HSA-2871837
IRAK1 recruits IKK complex R-HSA-937039
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ER-Phagosome pathway R-HSA-1236974
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
TCR signaling R-HSA-202403
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
p75 NTR receptor-mediated signalling R-HSA-193704
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
NF-kB is activated and signals survival R-HSA-209560
Activation of NF-kappaB in B cells R-HSA-1169091
NOD1/2 Signaling Pathway R-HSA-168638
IKK complex recruitment mediated by RIP1 R-HSA-937041
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Diseases of Immune System R-HSA-5260271
MAP kinase activation R-HSA-450294
p75NTR recruits signalling complexes R-HSA-209543
p75NTR signals via NF-kB R-HSA-193639
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88-independent TLR4 cascade R-HSA-166166
CLEC7A (Dectin-1) signaling R-HSA-5607764
SARS-CoV Infections R-HSA-9679506
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Infectious disease R-HSA-5663205
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Death Receptor Signaling R-HSA-73887
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Downstream TCR signaling R-HSA-202424
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
SARS-CoV-2-host interactions R-HSA-9705683
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-17 signaling R-HSA-448424
Interleukin-1 family signaling R-HSA-446652
Regulation of NF-kappa B signaling R-HSA-9758274
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
IkBA variant leads to EDA-ID R-HSA-5603029
MyD88 cascade initiated on plasma membrane R-HSA-975871
Class I MHC mediated antigen processing & presentation R-HSA-983169
IRAK1 recruits IKK complex R-HSA-937039
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Interleukin-17 signaling R-HSA-448424
IkBA variant leads to EDA-ID R-HSA-5603029
MyD88 dependent cascade initiated on endosome R-HSA-975155
p75NTR recruits signalling complexes R-HSA-209543
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Diseases of Immune System R-HSA-5260271
IKK complex recruitment mediated by RIP1 R-HSA-937041
Diseases associated with the TLR signaling cascade R-HSA-5602358
Innate Immune System R-HSA-168249
MyD88 cascade initiated on plasma membrane R-HSA-975871
FCERI mediated NF-kB activation R-HSA-2871837
C-type lectin receptors (CLRs) R-HSA-5621481
Death Receptor Signaling R-HSA-73887
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of NF-kappa B signaling R-HSA-9758274
Antigen processing-Cross presentation R-HSA-1236975
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Interleukin-1 signaling R-HSA-9020702
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
MyD88-independent TLR4 cascade R-HSA-166166
NOD1/2 Signaling Pathway R-HSA-168638
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-1 family signaling R-HSA-446652
Cytokine Signaling in Immune system R-HSA-1280215
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
NF-kB is activated and signals survival R-HSA-209560
Activation of NF-kappaB in B cells R-HSA-1169091
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
IKBKB deficiency causes SCID R-HSA-5602636
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by Interleukins R-HSA-449147
Downstream TCR signaling R-HSA-202424
SARS-CoV-2-host interactions R-HSA-9705683
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p75NTR signals via NF-kB R-HSA-193639
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Infectious disease R-HSA-5663205
SARS-CoV-2 Infection R-HSA-9694516
ER-Phagosome pathway R-HSA-1236974
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
MAP kinase activation R-HSA-450294
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TNF signaling R-HSA-75893
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Immune System R-HSA-168256
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
SARS-CoV Infections R-HSA-9679506
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
TCR signaling R-HSA-202403
TRAF6 mediated NF-kB activation R-HSA-933542
Signal Transduction R-HSA-162582
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Interleukin-1 family signaling R-HSA-446652
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
NF-kB is activated and signals survival R-HSA-209560
Diseases of Immune System R-HSA-5260271
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Interleukin-1 signaling R-HSA-9020702
Activation of NF-kappaB in B cells R-HSA-1169091
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Interleukin-17 signaling R-HSA-448424
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TCR signaling R-HSA-202403
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
SARS-CoV-2 Infection R-HSA-9694516
MyD88 dependent cascade initiated on endosome R-HSA-975155
Diseases associated with the TLR signaling cascade R-HSA-5602358
p75NTR recruits signalling complexes R-HSA-209543
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
p75 NTR receptor-mediated signalling R-HSA-193704
Class I MHC mediated antigen processing & presentation R-HSA-983169
IKK complex recruitment mediated by RIP1 R-HSA-937041
Infectious disease R-HSA-5663205
ER-Phagosome pathway R-HSA-1236974
FCERI mediated NF-kB activation R-HSA-2871837
TNF signaling R-HSA-75893
Antigen processing-Cross presentation R-HSA-1236975
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
p75NTR signals via NF-kB R-HSA-193639
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
IkBA variant leads to EDA-ID R-HSA-5603029
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Disease R-HSA-1643685
CLEC7A (Dectin-1) signaling R-HSA-5607764
SARS-CoV Infections R-HSA-9679506
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Regulation of NF-kappa B signaling R-HSA-9758274
SARS-CoV-2-host interactions R-HSA-9705683
MyD88-independent TLR4 cascade R-HSA-166166
IKBKB deficiency causes SCID R-HSA-5602636
IRAK1 recruits IKK complex R-HSA-937039
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Innate Immune System R-HSA-168249
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Downstream TCR signaling R-HSA-202424
Adaptive Immune System R-HSA-1280218
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Death Receptor Signaling R-HSA-73887
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
NOD1/2 Signaling Pathway R-HSA-168638
MyD88 cascade initiated on plasma membrane R-HSA-975871
Immune System R-HSA-168256
Toll-like Receptor Cascades R-HSA-168898
Regulation of TNFR1 signaling R-HSA-5357905
TRAF6 mediated NF-kB activation R-HSA-933542
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
C-type lectin receptors (CLRs) R-HSA-5621481
MAP kinase activation R-HSA-450294
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Innate Immune System R-HSA-168249
Death Receptor Signaling R-HSA-73887
NOD1/2 Signaling Pathway R-HSA-168638
Interleukin-1 family signaling R-HSA-446652
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
Interleukin-1 signaling R-HSA-9020702
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Activation of NF-kappaB in B cells R-HSA-1169091
p75NTR signals via NF-kB R-HSA-193639
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
Signaling by Interleukins R-HSA-449147
p75NTR recruits signalling complexes R-HSA-209543
Diseases associated with the TLR signaling cascade R-HSA-5602358
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
IKK complex recruitment mediated by RIP1 R-HSA-937041
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
MAP kinase activation R-HSA-450294
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Class I MHC mediated antigen processing & presentation R-HSA-983169
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Signal Transduction R-HSA-162582
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
C-type lectin receptors (CLRs) R-HSA-5621481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
IkBA variant leads to EDA-ID R-HSA-5603029
Interleukin-17 signaling R-HSA-448424
FCERI mediated NF-kB activation R-HSA-2871837
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88 dependent cascade initiated on endosome R-HSA-975155
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Toll-like Receptor Cascades R-HSA-168898
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Diseases of Immune System R-HSA-5260271
Downstream TCR signaling R-HSA-202424
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Regulation of NF-kappa B signaling R-HSA-9758274
SARS-CoV-2-host interactions R-HSA-9705683
SARS-CoV Infections R-HSA-9679506
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
SARS-CoV-2 Infection R-HSA-9694516
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Adaptive Immune System R-HSA-1280218
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TCR signaling R-HSA-202403
Regulation of TNFR1 signaling R-HSA-5357905
Antigen processing-Cross presentation R-HSA-1236975
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
NF-kB is activated and signals survival R-HSA-209560
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
IKBKB deficiency causes SCID R-HSA-5602636
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
p75 NTR receptor-mediated signalling R-HSA-193704
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
CLEC7A (Dectin-1) signaling R-HSA-5607764
TNF signaling R-HSA-75893
Infectious disease R-HSA-5663205
IRAK1 recruits IKK complex R-HSA-937039
TRAF6 mediated NF-kB activation R-HSA-933542
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Immune System R-HSA-168256
ER-Phagosome pathway R-HSA-1236974
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Disease R-HSA-1643685
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
CLEC7A (Dectin-1) signaling R-HSA-5607764
IkBA variant leads to EDA-ID R-HSA-5603029
Interleukin-1 family signaling R-HSA-446652
C-type lectin receptors (CLRs) R-HSA-5621481
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
p75NTR recruits signalling complexes R-HSA-209543
Diseases associated with the TLR signaling cascade R-HSA-5602358
p75NTR signals via NF-kB R-HSA-193639
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Antigen processing-Cross presentation R-HSA-1236975
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
NF-kB is activated and signals survival R-HSA-209560
Signaling by Interleukins R-HSA-449147
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cytokine Signaling in Immune system R-HSA-1280215
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
IRAK1 recruits IKK complex R-HSA-937039
SARS-CoV-2 Infection R-HSA-9694516
IKK complex recruitment mediated by RIP1 R-HSA-937041
Class I MHC mediated antigen processing & presentation R-HSA-983169
Downstream TCR signaling R-HSA-202424
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
NOD1/2 Signaling Pathway R-HSA-168638
Adaptive Immune System R-HSA-1280218
MyD88 dependent cascade initiated on endosome R-HSA-975155
Death Receptor Signaling R-HSA-73887
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Infectious disease R-HSA-5663205
Activation of NF-kappaB in B cells R-HSA-1169091
TRAF6 mediated NF-kB activation R-HSA-933542
Interleukin-17 signaling R-HSA-448424
TCR signaling R-HSA-202403
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulation of TNFR1 signaling R-HSA-5357905
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Innate Immune System R-HSA-168249
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Disease R-HSA-1643685
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Diseases of Immune System R-HSA-5260271
MAP kinase activation R-HSA-450294
Toll-like Receptor Cascades R-HSA-168898
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Immune System R-HSA-168256
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Regulation of NF-kappa B signaling R-HSA-9758274
TNF signaling R-HSA-75893
Interleukin-1 signaling R-HSA-9020702
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
SARS-CoV Infections R-HSA-9679506
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
SARS-CoV-2-host interactions R-HSA-9705683
Signal Transduction R-HSA-162582
p75 NTR receptor-mediated signalling R-HSA-193704
IKBKB deficiency causes SCID R-HSA-5602636
ER-Phagosome pathway R-HSA-1236974
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Infectious disease R-HSA-5663205
IKK complex recruitment mediated by RIP1 R-HSA-937041
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of NF-kappa B signaling R-HSA-9758274
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
TNF signaling R-HSA-75893
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Disease R-HSA-1643685
Signaling by Interleukins R-HSA-449147
IkBA variant leads to EDA-ID R-HSA-5603029
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
ER-Phagosome pathway R-HSA-1236974
Diseases associated with the TLR signaling cascade R-HSA-5602358
Regulation of TNFR1 signaling R-HSA-5357905
SARS-CoV Infections R-HSA-9679506
FCERI mediated NF-kB activation R-HSA-2871837
NOD1/2 Signaling Pathway R-HSA-168638
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Death Receptor Signaling R-HSA-73887
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
IKBKB deficiency causes SCID R-HSA-5602636
Toll-like Receptor Cascades R-HSA-168898
NF-kB is activated and signals survival R-HSA-209560
Interleukin-1 signaling R-HSA-9020702
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Class I MHC mediated antigen processing & presentation R-HSA-983169
Diseases of Immune System R-HSA-5260271
Innate Immune System R-HSA-168249
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Immune System R-HSA-168256
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
SARS-CoV-2-host interactions R-HSA-9705683
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
TCR signaling R-HSA-202403
p75NTR recruits signalling complexes R-HSA-209543
SARS-CoV-2 Infection R-HSA-9694516
Signal Transduction R-HSA-162582
CLEC7A (Dectin-1) signaling R-HSA-5607764
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Interleukin-1 family signaling R-HSA-446652
MyD88 dependent cascade initiated on endosome R-HSA-975155
Interleukin-17 signaling R-HSA-448424
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Downstream TCR signaling R-HSA-202424
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
MyD88-independent TLR4 cascade R-HSA-166166
Adaptive Immune System R-HSA-1280218
MAP kinase activation R-HSA-450294
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
p75NTR signals via NF-kB R-HSA-193639
C-type lectin receptors (CLRs) R-HSA-5621481
Antigen processing-Cross presentation R-HSA-1236975
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
IRAK1 recruits IKK complex R-HSA-937039
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Regulation of NF-kappa B signaling R-HSA-9758274
Activation of NF-kappaB in B cells R-HSA-1169091
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
IkBA variant leads to EDA-ID R-HSA-5603029
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
MAP kinase activation R-HSA-450294
Regulation of TNFR1 signaling R-HSA-5357905
C-type lectin receptors (CLRs) R-HSA-5621481
FCERI mediated NF-kB activation R-HSA-2871837
Innate Immune System R-HSA-168249
p75 NTR receptor-mediated signalling R-HSA-193704
CLEC7A (Dectin-1) signaling R-HSA-5607764
Immune System R-HSA-168256
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
p75NTR signals via NF-kB R-HSA-193639
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
SARS-CoV-2-host interactions R-HSA-9705683
Downstream TCR signaling R-HSA-202424
MyD88 cascade initiated on plasma membrane R-HSA-975871
Interleukin-17 signaling R-HSA-448424
Class I MHC mediated antigen processing & presentation R-HSA-983169
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Diseases associated with the TLR signaling cascade R-HSA-5602358
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
NF-kB is activated and signals survival R-HSA-209560
Signal Transduction R-HSA-162582
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
IRAK1 recruits IKK complex R-HSA-937039
SARS-CoV Infections R-HSA-9679506
Toll-like Receptor Cascades R-HSA-168898
Signaling by Interleukins R-HSA-449147
Infectious disease R-HSA-5663205
SARS-CoV-2 Infection R-HSA-9694516
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Interleukin-1 signaling R-HSA-9020702
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cytokine Signaling in Immune system R-HSA-1280215
Antigen processing-Cross presentation R-HSA-1236975
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88-independent TLR4 cascade R-HSA-166166
IKBKB deficiency causes SCID R-HSA-5602636
NOD1/2 Signaling Pathway R-HSA-168638
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Diseases of Immune System R-HSA-5260271
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 dependent cascade initiated on endosome R-HSA-975155
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Disease R-HSA-1643685
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
ER-Phagosome pathway R-HSA-1236974
IKK complex recruitment mediated by RIP1 R-HSA-937041
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
TCR signaling R-HSA-202403
p75NTR recruits signalling complexes R-HSA-209543
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TNF signaling R-HSA-75893

Expression Atlas ENSG00000104365
LRG display in Ensembl gene LRG_1241
NCBI gene (formerly Entrezgene) 3551
GeneCards 5960
HGNC Symbol HGNC:5960
MIM gene 603258
MIM morbid 618204
UniProtKB Gene Name O14920
WikiGene 3551
Gene: NTRK2
Ensembl ID : ENSG00000148053
Description: neurotrophic receptor tyrosine kinase 2
Gene Synonyms: TRKB
3 APIs:
288 Possible Orthologues:

NTF4 activates NTRK2 (TRKB) signaling R-HSA-9026357
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NGF-independant TRKA activation R-HSA-187024
Activation of TRKA receptors R-HSA-187015
NTF3 activates NTRK2 (TRKB) signaling R-HSA-9025046
Activated NTRK2 signals through PLCG1 R-HSA-9026527
NTRK2 activates RAC1 R-HSA-9032759
BDNF activates NTRK2 (TRKB) signaling R-HSA-9024909
Signaling by NTRKs R-HSA-166520
Signaling by NTRK2 (TRKB) R-HSA-9006115
Activated NTRK2 signals through FYN R-HSA-9032500
Signaling by NTRK1 (TRKA) R-HSA-187037
Signal Transduction R-HSA-162582
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
Activated NTRK2 signals through RAS R-HSA-9026519
Activated NTRK2 signals through CDK5 R-HSA-9032845
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activated NTRK2 signals through CDK5 R-HSA-9032845
NGF-independant TRKA activation R-HSA-187024
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by NTRKs R-HSA-166520
NTRK2 activates RAC1 R-HSA-9032759
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
Activated NTRK2 signals through RAS R-HSA-9026519
Activated NTRK2 signals through PLCG1 R-HSA-9026527
Signal Transduction R-HSA-162582
Activated NTRK2 signals through FYN R-HSA-9032500
NTF3 activates NTRK2 (TRKB) signaling R-HSA-9025046
NTF4 activates NTRK2 (TRKB) signaling R-HSA-9026357
BDNF activates NTRK2 (TRKB) signaling R-HSA-9024909
Activation of TRKA receptors R-HSA-187015
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by NTRK2 (TRKB) R-HSA-9006115
NTF3 activates NTRK2 (TRKB) signaling R-HSA-9025046
Activated NTRK2 signals through CDK5 R-HSA-9032845
Activated NTRK2 signals through RAS R-HSA-9026519
Activation of TRKA receptors R-HSA-187015
Activated NTRK2 signals through PLCG1 R-HSA-9026527
Signaling by NTRKs R-HSA-166520
Activated NTRK2 signals through PI3K R-HSA-9028335
NGF-independant TRKA activation R-HSA-187024
Signaling by NTRK2 (TRKB) R-HSA-9006115
Activated NTRK2 signals through FYN R-HSA-9032500
NTRK2 activates RAC1 R-HSA-9032759
BDNF activates NTRK2 (TRKB) signaling R-HSA-9024909
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
NTF4 activates NTRK2 (TRKB) signaling R-HSA-9026357
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRK1 (TRKA) R-HSA-187037
NGF-independant TRKA activation R-HSA-187024
Signaling by NTRK1 (TRKA) R-HSA-187037
NTRK2 activates RAC1 R-HSA-9032759
BDNF activates NTRK2 (TRKB) signaling R-HSA-9024909
Activated NTRK2 signals through PLCG1 R-HSA-9026527
Activated NTRK2 signals through CDK5 R-HSA-9032845
Activated NTRK2 signals through FYN R-HSA-9032500
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
NTF4 activates NTRK2 (TRKB) signaling R-HSA-9026357
Signaling by NTRKs R-HSA-166520
Activated NTRK2 signals through RAS R-HSA-9026519
Activation of TRKA receptors R-HSA-187015
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTF3 activates NTRK2 (TRKB) signaling R-HSA-9025046
Signal Transduction R-HSA-162582
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by NTRK2 (TRKB) R-HSA-9006115
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
Signal Transduction R-HSA-162582
NTF4 activates NTRK2 (TRKB) signaling R-HSA-9026357
Signaling by NTRK2 (TRKB) R-HSA-9006115
NTRK2 activates RAC1 R-HSA-9032759
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activated NTRK2 signals through RAS R-HSA-9026519
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by NTRKs R-HSA-166520
Activated NTRK2 signals through PLCG1 R-HSA-9026527
Activated NTRK2 signals through FYN R-HSA-9032500
BDNF activates NTRK2 (TRKB) signaling R-HSA-9024909
Activation of TRKA receptors R-HSA-187015
NTF3 activates NTRK2 (TRKB) signaling R-HSA-9025046
NGF-independant TRKA activation R-HSA-187024
Activated NTRK2 signals through CDK5 R-HSA-9032845
Activated NTRK2 signals through PLCG1 R-HSA-9026527
Signaling by NTRKs R-HSA-166520
NTF4 activates NTRK2 (TRKB) signaling R-HSA-9026357
Activated NTRK2 signals through CDK5 R-HSA-9032845
NTRK2 activates RAC1 R-HSA-9032759
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Activated NTRK2 signals through RAS R-HSA-9026519
Activation of TRKA receptors R-HSA-187015
NTF3 activates NTRK2 (TRKB) signaling R-HSA-9025046
BDNF activates NTRK2 (TRKB) signaling R-HSA-9024909
Signaling by NTRK2 (TRKB) R-HSA-9006115
Activated NTRK2 signals through FYN R-HSA-9032500
NGF-independant TRKA activation R-HSA-187024
Signaling by NTRK1 (TRKA) R-HSA-187037
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by NTRK2 (TRKB) R-HSA-9006115
NTF4 activates NTRK2 (TRKB) signaling R-HSA-9026357
Activated NTRK2 signals through CDK5 R-HSA-9032845
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by NTRKs R-HSA-166520
Activated NTRK2 signals through FYN R-HSA-9032500
BDNF activates NTRK2 (TRKB) signaling R-HSA-9024909
NTRK2 activates RAC1 R-HSA-9032759
Signal Transduction R-HSA-162582
NTF3 activates NTRK2 (TRKB) signaling R-HSA-9025046
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
Activated NTRK2 signals through RAS R-HSA-9026519
Activation of TRKA receptors R-HSA-187015
Signaling by NTRK1 (TRKA) R-HSA-187037
NGF-independant TRKA activation R-HSA-187024
Activated NTRK2 signals through PLCG1 R-HSA-9026527
Signaling by NTRK2 (TRKB) R-HSA-9006115
Activated NTRK2 signals through FYN R-HSA-9032500
Activated NTRK2 signals through CDK5 R-HSA-9032845
Signaling by NTRK1 (TRKA) R-HSA-187037
BDNF activates NTRK2 (TRKB) signaling R-HSA-9024909
NTRK2 activates RAC1 R-HSA-9032759
Signal Transduction R-HSA-162582
Activated NTRK2 signals through PI3K R-HSA-9028335
NTF4 activates NTRK2 (TRKB) signaling R-HSA-9026357
Activation of TRKA receptors R-HSA-187015
Activated NTRK2 signals through RAS R-HSA-9026519
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
NGF-independant TRKA activation R-HSA-187024
Signaling by NTRKs R-HSA-166520
Activated NTRK2 signals through PLCG1 R-HSA-9026527
NTF3 activates NTRK2 (TRKB) signaling R-HSA-9025046
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activated NTRK2 signals through FYN R-HSA-9032500
Signaling by NTRKs R-HSA-166520
Signaling by NTRK1 (TRKA) R-HSA-187037
Activated NTRK2 signals through CDK5 R-HSA-9032845
Signaling by NTRK2 (TRKB) R-HSA-9006115
Activated NTRK2 signals through RAS R-HSA-9026519
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activated NTRK2 signals through PI3K R-HSA-9028335
Signal Transduction R-HSA-162582
BDNF activates NTRK2 (TRKB) signaling R-HSA-9024909
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
Activation of TRKA receptors R-HSA-187015
NGF-independant TRKA activation R-HSA-187024
NTF3 activates NTRK2 (TRKB) signaling R-HSA-9025046
NTF4 activates NTRK2 (TRKB) signaling R-HSA-9026357
Activated NTRK2 signals through PLCG1 R-HSA-9026527
NTRK2 activates RAC1 R-HSA-9032759
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
NGF-independant TRKA activation R-HSA-187024
Activated NTRK2 signals through PLCG1 R-HSA-9026527
Signaling by NTRKs R-HSA-166520
Activated NTRK2 signals through CDK5 R-HSA-9032845
Signal Transduction R-HSA-162582
NTF4 activates NTRK2 (TRKB) signaling R-HSA-9026357
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTRK2 activates RAC1 R-HSA-9032759
BDNF activates NTRK2 (TRKB) signaling R-HSA-9024909
Activated NTRK2 signals through FYN R-HSA-9032500
NTF3 activates NTRK2 (TRKB) signaling R-HSA-9025046
Activated NTRK2 signals through RAS R-HSA-9026519
Signaling by NTRK2 (TRKB) R-HSA-9006115
Activation of TRKA receptors R-HSA-187015
Activated NTRK2 signals through PI3K R-HSA-9028335

Expression Atlas ENSG00000148053
NCBI gene (formerly Entrezgene) 4915
GeneCards 8032
HGNC Symbol HGNC:8032
MIM gene 600456
MIM morbid 617830
UniProtKB Gene Name Q5VWE5
WikiGene 4915