Gene: CDK9
Ensembl ID : ENSG00000136807
Description: cyclin dependent kinase 9
Gene Synonyms: C-2K,CDC2L4,PITALRE,TAK
7 APIs:
207 Possible Orthologues:

HIV elongation arrest and recovery R-HSA-167287
Signaling by TGFB family members R-HSA-9006936
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
HIV Life Cycle R-HSA-162587
RNA polymerase II transcribes snRNA genes R-HSA-6807505
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
Transcriptional Regulation by TP53 R-HSA-3700989
Estrogen-dependent gene expression R-HSA-9018519
Pausing and recovery of HIV elongation R-HSA-167290
RNA Polymerase II Transcription Elongation R-HSA-75955
Late Phase of HIV Life Cycle R-HSA-162599
HIV Transcription Elongation R-HSA-167169
RNA Polymerase II Transcription R-HSA-73857
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
Signaling by TGF-beta Receptor Complex R-HSA-170834
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Disease R-HSA-1643685
RNA Polymerase II Pre-transcription Events R-HSA-674695
Formation of RNA Pol II elongation complex R-HSA-112382
ESR-mediated signaling R-HSA-8939211
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
Infectious disease R-HSA-5663205
Interactions of Tat with host cellular proteins R-HSA-176034
Host Interactions of HIV factors R-HSA-162909
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
Transcription of the HIV genome R-HSA-167172
Signaling by Nuclear Receptors R-HSA-9006931
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Transcriptional Regulation by TP53 R-HSA-3700989
HIV Transcription Elongation R-HSA-167169
Infectious disease R-HSA-5663205
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
HIV Infection R-HSA-162906
Signaling by TGF-beta Receptor Complex R-HSA-170834
Transcription of the HIV genome R-HSA-167172
RNA Polymerase II Transcription Elongation R-HSA-75955
Generic Transcription Pathway R-HSA-212436
ESR-mediated signaling R-HSA-8939211
HIV Life Cycle R-HSA-162587
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Estrogen-dependent gene expression R-HSA-9018519
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
Late Phase of HIV Life Cycle R-HSA-162599
RNA Polymerase II Transcription R-HSA-73857
RNA polymerase II transcribes snRNA genes R-HSA-6807505
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Formation of RNA Pol II elongation complex R-HSA-112382
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by TGFB family members R-HSA-9006936
Interactions of Tat with host cellular proteins R-HSA-176034
Pausing and recovery of HIV elongation R-HSA-167290
Disease R-HSA-1643685
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Pre-transcription Events R-HSA-674695
Signal Transduction R-HSA-162582
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
HIV elongation arrest and recovery R-HSA-167287
Host Interactions of HIV factors R-HSA-162909
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
RNA polymerase II transcribes snRNA genes R-HSA-6807505
HIV Transcription Elongation R-HSA-167169
Infectious disease R-HSA-5663205
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by TP53 R-HSA-3700989
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Formation of RNA Pol II elongation complex R-HSA-112382
HIV Life Cycle R-HSA-162587
Late Phase of HIV Life Cycle R-HSA-162599
Disease R-HSA-1643685
Signaling by Nuclear Receptors R-HSA-9006931
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
RNA Polymerase II Transcription R-HSA-73857
ESR-mediated signaling R-HSA-8939211
Signaling by TGFB family members R-HSA-9006936
Host Interactions of HIV factors R-HSA-162909
HIV Infection R-HSA-162906
Pausing and recovery of HIV elongation R-HSA-167290
Transcription of the HIV genome R-HSA-167172
Estrogen-dependent gene expression R-HSA-9018519
HIV elongation arrest and recovery R-HSA-167287
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Interactions of Tat with host cellular proteins R-HSA-176034
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
RNA Polymerase II Pre-transcription Events R-HSA-674695
Signaling by TGF-beta Receptor Complex R-HSA-170834
RNA Polymerase II Transcription Elongation R-HSA-75955
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
HIV Infection R-HSA-162906
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
Interactions of Tat with host cellular proteins R-HSA-176034
HIV Transcription Elongation R-HSA-167169
HIV Life Cycle R-HSA-162587
Formation of RNA Pol II elongation complex R-HSA-112382
RNA polymerase II transcribes snRNA genes R-HSA-6807505
Estrogen-dependent gene expression R-HSA-9018519
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
Late Phase of HIV Life Cycle R-HSA-162599
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
HIV elongation arrest and recovery R-HSA-167287
Signaling by TGFB family members R-HSA-9006936
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
RNA Polymerase II Pre-transcription Events R-HSA-674695
ESR-mediated signaling R-HSA-8939211
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signal Transduction R-HSA-162582
Pausing and recovery of HIV elongation R-HSA-167290
RNA Polymerase II Transcription Elongation R-HSA-75955
Signaling by TGF-beta Receptor Complex R-HSA-170834
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Nuclear Receptors R-HSA-9006931
Transcription of the HIV genome R-HSA-167172
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Host Interactions of HIV factors R-HSA-162909
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Pausing and recovery of HIV elongation R-HSA-167290
Interactions of Tat with host cellular proteins R-HSA-176034
HIV Transcription Elongation R-HSA-167169
RNA polymerase II transcribes snRNA genes R-HSA-6807505
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
HIV Life Cycle R-HSA-162587
Signaling by Nuclear Receptors R-HSA-9006931
HIV Infection R-HSA-162906
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
RNA Polymerase II Pre-transcription Events R-HSA-674695
RNA Polymerase II Transcription Elongation R-HSA-75955
Gene expression (Transcription) R-HSA-74160
Host Interactions of HIV factors R-HSA-162909
Disease R-HSA-1643685
Estrogen-dependent gene expression R-HSA-9018519
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
Signaling by TGF-beta Receptor Complex R-HSA-170834
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Transcription of the HIV genome R-HSA-167172
Formation of RNA Pol II elongation complex R-HSA-112382
Signaling by TGFB family members R-HSA-9006936
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
Infectious disease R-HSA-5663205
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
HIV elongation arrest and recovery R-HSA-167287
ESR-mediated signaling R-HSA-8939211
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Late Phase of HIV Life Cycle R-HSA-162599
Signal Transduction R-HSA-162582
HIV Transcription Elongation R-HSA-167169
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
Interactions of Tat with host cellular proteins R-HSA-176034
Formation of RNA Pol II elongation complex R-HSA-112382
Signaling by Nuclear Receptors R-HSA-9006931
Late Phase of HIV Life Cycle R-HSA-162599
ESR-mediated signaling R-HSA-8939211
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Signaling by TGFB family members R-HSA-9006936
Generic Transcription Pathway R-HSA-212436
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Disease R-HSA-1643685
Transcription of the HIV genome R-HSA-167172
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
Pausing and recovery of HIV elongation R-HSA-167290
Transcriptional Regulation by TP53 R-HSA-3700989
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription Elongation R-HSA-75955
RNA polymerase II transcribes snRNA genes R-HSA-6807505
Signal Transduction R-HSA-162582
Infectious disease R-HSA-5663205
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Estrogen-dependent gene expression R-HSA-9018519
HIV Life Cycle R-HSA-162587
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Host Interactions of HIV factors R-HSA-162909
Signaling by TGF-beta Receptor Complex R-HSA-170834
HIV elongation arrest and recovery R-HSA-167287
RNA Polymerase II Pre-transcription Events R-HSA-674695
Transcription of the HIV genome R-HSA-167172
Generic Transcription Pathway R-HSA-212436
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Transcriptional Regulation by TP53 R-HSA-3700989
Disease R-HSA-1643685
RNA Polymerase II Pre-transcription Events R-HSA-674695
Signaling by Nuclear Receptors R-HSA-9006931
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
Signal Transduction R-HSA-162582
ESR-mediated signaling R-HSA-8939211
Formation of RNA Pol II elongation complex R-HSA-112382
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
RNA polymerase II transcribes snRNA genes R-HSA-6807505
Late Phase of HIV Life Cycle R-HSA-162599
RNA Polymerase II Transcription Elongation R-HSA-75955
Pausing and recovery of HIV elongation R-HSA-167290
HIV elongation arrest and recovery R-HSA-167287
Signaling by TGF-beta Receptor Complex R-HSA-170834
HIV Life Cycle R-HSA-162587
HIV Infection R-HSA-162906
Interactions of Tat with host cellular proteins R-HSA-176034
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Host Interactions of HIV factors R-HSA-162909
RNA Polymerase II Transcription R-HSA-73857
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
Estrogen-dependent gene expression R-HSA-9018519
Infectious disease R-HSA-5663205
Signaling by TGFB family members R-HSA-9006936
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
HIV Transcription Elongation R-HSA-167169
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
RNA Polymerase II Pre-transcription Events R-HSA-674695
Signaling by TGFB family members R-HSA-9006936
HIV Infection R-HSA-162906
Host Interactions of HIV factors R-HSA-162909
Signal Transduction R-HSA-162582
Formation of RNA Pol II elongation complex R-HSA-112382
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Transcriptional Regulation by TP53 R-HSA-3700989
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Estrogen-dependent gene expression R-HSA-9018519
Signaling by TGF-beta Receptor Complex R-HSA-170834
RNA polymerase II transcribes snRNA genes R-HSA-6807505
Infectious disease R-HSA-5663205
HIV Life Cycle R-HSA-162587
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
RNA Polymerase II Transcription Elongation R-HSA-75955
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
HIV elongation arrest and recovery R-HSA-167287
Pausing and recovery of HIV elongation R-HSA-167290
Gene expression (Transcription) R-HSA-74160
Signaling by Nuclear Receptors R-HSA-9006931
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
ESR-mediated signaling R-HSA-8939211
Transcription of the HIV genome R-HSA-167172
Interactions of Tat with host cellular proteins R-HSA-176034
HIV Transcription Elongation R-HSA-167169
Late Phase of HIV Life Cycle R-HSA-162599
Pausing and recovery of HIV elongation R-HSA-167290
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by TGFB family members R-HSA-9006936
Transcription of the HIV genome R-HSA-167172
Signaling by TGF-beta Receptor Complex R-HSA-170834
HIV Life Cycle R-HSA-162587
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
ESR-mediated signaling R-HSA-8939211
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Signal Transduction R-HSA-162582
Interactions of Tat with host cellular proteins R-HSA-176034
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
HIV Transcription Elongation R-HSA-167169
Estrogen-dependent gene expression R-HSA-9018519
RNA Polymerase II Pre-transcription Events R-HSA-674695
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Disease R-HSA-1643685
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Host Interactions of HIV factors R-HSA-162909
RNA Polymerase II Transcription R-HSA-73857
Infectious disease R-HSA-5663205
Transcriptional Regulation by TP53 R-HSA-3700989
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription Elongation R-HSA-75955
Generic Transcription Pathway R-HSA-212436
RNA polymerase II transcribes snRNA genes R-HSA-6807505
Formation of RNA Pol II elongation complex R-HSA-112382
HIV Infection R-HSA-162906
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
HIV elongation arrest and recovery R-HSA-167287
Late Phase of HIV Life Cycle R-HSA-162599
Formation of RNA Pol II elongation complex R-HSA-112382
ESR-mediated signaling R-HSA-8939211
Disease R-HSA-1643685
Pausing and recovery of HIV elongation R-HSA-167290
Generic Transcription Pathway R-HSA-212436
Signaling by TGF-beta Receptor Complex R-HSA-170834
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
RNA polymerase II transcribes snRNA genes R-HSA-6807505
Signaling by Nuclear Receptors R-HSA-9006931
Late Phase of HIV Life Cycle R-HSA-162599
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
HIV Infection R-HSA-162906
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Signaling by TGFB family members R-HSA-9006936
RNA Polymerase II Transcription R-HSA-73857
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
Transcription of the HIV genome R-HSA-167172
Estrogen-dependent gene expression R-HSA-9018519
Signal Transduction R-HSA-162582
Host Interactions of HIV factors R-HSA-162909
HIV elongation arrest and recovery R-HSA-167287
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
HIV Life Cycle R-HSA-162587
Transcriptional Regulation by TP53 R-HSA-3700989
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
RNA Polymerase II Transcription Elongation R-HSA-75955
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
HIV Transcription Elongation R-HSA-167169
Interactions of Tat with host cellular proteins R-HSA-176034
RNA Polymerase II Pre-transcription Events R-HSA-674695
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Transcriptional Regulation by TP53 R-HSA-3700989
Estrogen-dependent gene expression R-HSA-9018519
RNA Polymerase II Pre-transcription Events R-HSA-674695
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Transcription of the HIV genome R-HSA-167172
Pausing and recovery of HIV elongation R-HSA-167290
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
Gene expression (Transcription) R-HSA-74160
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Host Interactions of HIV factors R-HSA-162909
Late Phase of HIV Life Cycle R-HSA-162599
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
ESR-mediated signaling R-HSA-8939211
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Signal Transduction R-HSA-162582
RNA polymerase II transcribes snRNA genes R-HSA-6807505
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
HIV elongation arrest and recovery R-HSA-167287
HIV Infection R-HSA-162906
Signaling by TGFB family members R-HSA-9006936
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
Formation of RNA Pol II elongation complex R-HSA-112382
Signaling by TGF-beta Receptor Complex R-HSA-170834
RNA Polymerase II Transcription Elongation R-HSA-75955
RNA Polymerase II Transcription R-HSA-73857
HIV Transcription Elongation R-HSA-167169
Signaling by Nuclear Receptors R-HSA-9006931
Interactions of Tat with host cellular proteins R-HSA-176034
HIV Life Cycle R-HSA-162587
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Infectious disease R-HSA-5663205

Expression Atlas ENSG00000136807
NCBI gene (formerly Entrezgene) 1025
GeneCards 1780
HGNC Symbol HGNC:1780
MIM gene 603251
UniProtKB Gene Name X6RE90
WikiGene 1025
Gene: PRKACG
Ensembl ID : ENSG00000165059
Description: protein kinase cAMP-activated catalytic subunit gamma
Gene Synonyms: PKACG
1 APIs:
365 Possible Orthologues:

Plasma lipoprotein assembly R-HSA-8963898
Transport of small molecules R-HSA-382551
Integration of energy metabolism R-HSA-163685
G-protein mediated events R-HSA-112040
Disease R-HSA-1643685
Immune System R-HSA-168256
Degradation of GLI1 by the proteasome R-HSA-5610780
Ca-dependent events R-HSA-111996
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Hemostasis R-HSA-109582
Factors involved in megakaryocyte development and platelet production R-HSA-983231
DAG and IP3 signaling R-HSA-1489509
Signal Transduction R-HSA-162582
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720
MAPK6/MAPK4 signaling R-HSA-5687128
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358
ROBO receptors bind AKAP5 R-HSA-9010642
G alpha (i) signalling events R-HSA-418594
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
PLC beta mediated events R-HSA-112043
PKA activation in glucagon signalling R-HSA-164378
Signaling by ROBO receptors R-HSA-376176
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
VEGFA-VEGFR2 Pathway R-HSA-4420097
C-type lectin receptors (CLRs) R-HSA-5621481
Triglyceride catabolism R-HSA-163560
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676
Opioid Signalling R-HSA-111885
Developmental Biology R-HSA-1266738
Post NMDA receptor activation events R-HSA-438064
CD209 (DC-SIGN) signaling R-HSA-5621575
Glycolysis R-HSA-70171
RET signaling R-HSA-8853659
GPCR downstream signalling R-HSA-388396
Neuronal System R-HSA-112316
Signaling by Hedgehog R-HSA-5358351
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040
Leishmania infection R-HSA-9658195
Glucose metabolism R-HSA-70326
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Metabolism R-HSA-1430728
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
Leishmania parasite growth and survival R-HSA-9664433
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600
Hedgehog 'off' state R-HSA-5610787
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
MAPK family signaling cascades R-HSA-5683057
Calmodulin induced events R-HSA-111933
Aquaporin-mediated transport R-HSA-445717
Intracellular signaling by second messengers R-HSA-9006925
Triglyceride metabolism R-HSA-8979227
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Rap1 signalling R-HSA-392517
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by VEGF R-HSA-194138
PKA activation R-HSA-163615
Signaling by GPCR R-HSA-372790
Metabolism of carbohydrates R-HSA-71387
Glucagon signaling in metabolic regulation R-HSA-163359
GPER1 signaling R-HSA-9634597
G alpha (s) signalling events R-HSA-418555
PKA-mediated phosphorylation of CREB R-HSA-111931
Regulation of insulin secretion R-HSA-422356
DARPP-32 events R-HSA-180024
Nervous system development R-HSA-9675108
Adaptive Immune System R-HSA-1280218
HDL assembly R-HSA-8963896
CaM pathway R-HSA-111997
Metabolism of lipids R-HSA-556833
Transmission across Chemical Synapses R-HSA-112315
DARPP-32 events R-HSA-180024
PKA activation in glucagon signalling R-HSA-164378
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
RET signaling R-HSA-8853659
Immune System R-HSA-168256
G alpha (s) signalling events R-HSA-418555
Leishmania parasite growth and survival R-HSA-9664433
Opioid Signalling R-HSA-111885
GPCR downstream signalling R-HSA-388396
Innate Immune System R-HSA-168249
Glycolysis R-HSA-70171
HDL assembly R-HSA-8963896
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676
Disease R-HSA-1643685
Glucose metabolism R-HSA-70326
PKA-mediated phosphorylation of CREB R-HSA-111931
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Glucagon signaling in metabolic regulation R-HSA-163359
PLC beta mediated events R-HSA-112043
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040
Developmental Biology R-HSA-1266738
Neuronal System R-HSA-112316
Ca-dependent events R-HSA-111996
Signaling by ROBO receptors R-HSA-376176
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog 'off' state R-HSA-5610787
Metabolism R-HSA-1430728
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Aquaporin-mediated transport R-HSA-445717
Signaling by GPCR R-HSA-372790
G-protein mediated events R-HSA-112040
Triglyceride catabolism R-HSA-163560
Integration of energy metabolism R-HSA-163685
Transport of small molecules R-HSA-382551
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of carbohydrates R-HSA-71387
Metabolism of lipids R-HSA-556833
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by VEGF R-HSA-194138
Regulation of insulin secretion R-HSA-422356
Hemostasis R-HSA-109582
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Post NMDA receptor activation events R-HSA-438064
Axon guidance R-HSA-422475
DAG and IP3 signaling R-HSA-1489509
VEGFA-VEGFR2 Pathway R-HSA-4420097
Triglyceride metabolism R-HSA-8979227
CaM pathway R-HSA-111997
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358
ROBO receptors bind AKAP5 R-HSA-9010642
Transmission across Chemical Synapses R-HSA-112315
G alpha (i) signalling events R-HSA-418594
PKA activation R-HSA-163615
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720
Rap1 signalling R-HSA-392517
CD209 (DC-SIGN) signaling R-HSA-5621575
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Degradation of GLI2 by the proteasome R-HSA-5610783
Infectious disease R-HSA-5663205
GPER1 signaling R-HSA-9634597
Leishmania infection R-HSA-9658195
MAPK family signaling cascades R-HSA-5683057
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600
C-type lectin receptors (CLRs) R-HSA-5621481
Calmodulin induced events R-HSA-111933
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Plasma lipoprotein assembly R-HSA-8963898
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Signaling by Hedgehog R-HSA-5358351
Nervous system development R-HSA-9675108

Expression Atlas ENSG00000165059
LRG display in Ensembl gene LRG_1004
NCBI gene (formerly Entrezgene) 5568
GeneCards 9382
HGNC Symbol HGNC:9382
MIM gene 176893
MIM morbid 616176
UniProtKB Gene Name P22612
WikiGene 5568
Gene: MAPK14
Ensembl ID : ENSG00000112062
Description: mitogen-activated protein kinase 14
Gene Synonyms: CSBP1,CSBP2,CSPB1,MXI2,P38,PRKM14,PRKM15
35 APIs:
292 Possible Orthologues:

MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Disease R-HSA-1643685
p38MAPK events R-HSA-171007
Disease R-HSA-1643685
Platelet homeostasis R-HSA-418346
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stimuli R-HSA-8953897
Organelle biogenesis and maintenance R-HSA-1852241
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Metabolism of RNA R-HSA-8953854
Signaling by NTRKs R-HSA-166520
Leishmania parasite growth and survival R-HSA-9664433
VEGFA-VEGFR2 Pathway R-HSA-4420097
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Cellular responses to stress R-HSA-2262752
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Myogenesis R-HSA-525793
RHO GTPase Effectors R-HSA-195258
Cellular Senescence R-HSA-2559583
MyD88 dependent cascade initiated on endosome R-HSA-975155
Developmental Biology R-HSA-1266738
Hemostasis R-HSA-109582
Interleukin-17 signaling R-HSA-448424
DSCAM interactions R-HSA-376172
Toll-like Receptor Cascades R-HSA-168898
Signal amplification R-HSA-392518
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
MAP kinase activation R-HSA-450294
MyD88-independent TLR4 cascade R-HSA-166166
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Transcriptional Regulation by TP53 R-HSA-3700989
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Nervous system development R-HSA-9675108
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by Rho GTPases R-HSA-194315
Innate Immune System R-HSA-168249
CD163 mediating an anti-inflammatory response R-HSA-9662834
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Netrin-1 signaling R-HSA-373752
Platelet sensitization by LDL R-HSA-432142
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOD1/2 Signaling Pathway R-HSA-168638
Regulation of TP53 Activity R-HSA-5633007
Axon guidance R-HSA-422475
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Platelet activation, signaling and aggregation R-HSA-76002
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Neutrophil degranulation R-HSA-6798695
Signaling by VEGF R-HSA-194138
Activation of the AP-1 family of transcription factors R-HSA-450341
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
ERK/MAPK targets R-HSA-198753
Signal Transduction R-HSA-162582
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signalling to RAS R-HSA-167044
Mitochondrial biogenesis R-HSA-1592230
Leishmania infection R-HSA-9658195
Infectious disease R-HSA-5663205
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Signalling to ERKs R-HSA-187687
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Signal amplification R-HSA-392518
Signaling by NTRK1 (TRKA) R-HSA-187037
Nervous system development R-HSA-9675108
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Platelet homeostasis R-HSA-418346
Cellular responses to stimuli R-HSA-8953897
Signaling by NTRKs R-HSA-166520
RNA Polymerase II Transcription R-HSA-73857
Oxidative Stress Induced Senescence R-HSA-2559580
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
p38MAPK events R-HSA-171007
Infectious disease R-HSA-5663205
ERK/MAPK targets R-HSA-198753
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Activation of the AP-1 family of transcription factors R-HSA-450341
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
Axon guidance R-HSA-422475
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Mitochondrial biogenesis R-HSA-1592230
Signalling to RAS R-HSA-167044
MyD88 dependent cascade initiated on endosome R-HSA-975155
Leishmania parasite growth and survival R-HSA-9664433
MAP kinase activation R-HSA-450294
Interleukin-17 signaling R-HSA-448424
Platelet sensitization by LDL R-HSA-432142
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signalling to ERKs R-HSA-187687
Organelle biogenesis and maintenance R-HSA-1852241
Cellular responses to stress R-HSA-2262752
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
CD163 mediating an anti-inflammatory response R-HSA-9662834
Disease R-HSA-1643685
NOD1/2 Signaling Pathway R-HSA-168638
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Immune System R-HSA-168256
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Gene expression (Transcription) R-HSA-74160
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by Rho GTPases R-HSA-194315
DSCAM interactions R-HSA-376172
VEGFA-VEGFR2 Pathway R-HSA-4420097
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Netrin-1 signaling R-HSA-373752
Signaling by VEGF R-HSA-194138
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Regulation of TP53 Activity R-HSA-5633007
RHO GTPase Effectors R-HSA-195258
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signal Transduction R-HSA-162582
Toll-like Receptor Cascades R-HSA-168898
Transcriptional Regulation by TP53 R-HSA-3700989
Cellular Senescence R-HSA-2559583
Metabolism of RNA R-HSA-8953854
Hemostasis R-HSA-109582
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Neutrophil degranulation R-HSA-6798695
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Myogenesis R-HSA-525793
Innate Immune System R-HSA-168249
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Leishmania infection R-HSA-9658195
Netrin-1 signaling R-HSA-373752
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Platelet activation, signaling and aggregation R-HSA-76002
RNA Polymerase II Transcription R-HSA-73857
Immune System R-HSA-168256
Disease R-HSA-1643685
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity R-HSA-5633007
Infectious disease R-HSA-5663205
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by NTRKs R-HSA-166520
Signalling to ERKs R-HSA-187687
Toll-like Receptor Cascades R-HSA-168898
Cytokine Signaling in Immune system R-HSA-1280215
Oxidative Stress Induced Senescence R-HSA-2559580
Activation of the AP-1 family of transcription factors R-HSA-450341
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Leishmania parasite growth and survival R-HSA-9664433
MyD88 dependent cascade initiated on endosome R-HSA-975155
Interleukin-17 signaling R-HSA-448424
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stress R-HSA-2262752
MyD88 cascade initiated on plasma membrane R-HSA-975871
Myogenesis R-HSA-525793
Signal amplification R-HSA-392518
MAP kinase activation R-HSA-450294
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Innate Immune System R-HSA-168249
Platelet homeostasis R-HSA-418346
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
RHO GTPase Effectors R-HSA-195258
p38MAPK events R-HSA-171007
Generic Transcription Pathway R-HSA-212436
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cellular Senescence R-HSA-2559583
Signaling by NTRK1 (TRKA) R-HSA-187037
Metabolism of RNA R-HSA-8953854
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signalling to RAS R-HSA-167044
Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
DSCAM interactions R-HSA-376172
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Neutrophil degranulation R-HSA-6798695
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
NOD1/2 Signaling Pathway R-HSA-168638
Axon guidance R-HSA-422475
Cellular responses to stimuli R-HSA-8953897
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signal Transduction R-HSA-162582
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Leishmania infection R-HSA-9658195
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Nervous system development R-HSA-9675108
ERK/MAPK targets R-HSA-198753
Organelle biogenesis and maintenance R-HSA-1852241
Transcriptional Regulation by TP53 R-HSA-3700989
MyD88-independent TLR4 cascade R-HSA-166166
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Interleukins R-HSA-449147
Hemostasis R-HSA-109582
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Rho GTPases R-HSA-194315
Platelet sensitization by LDL R-HSA-432142
Mitochondrial biogenesis R-HSA-1592230
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Developmental Biology R-HSA-1266738
CD163 mediating an anti-inflammatory response R-HSA-9662834
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Toll-like Receptor Cascades R-HSA-168898
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
NOD1/2 Signaling Pathway R-HSA-168638
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by NTRKs R-HSA-166520
Myogenesis R-HSA-525793
Signalling to RAS R-HSA-167044
RHO GTPase Effectors R-HSA-195258
Nervous system development R-HSA-9675108
Leishmania parasite growth and survival R-HSA-9664433
Developmental Biology R-HSA-1266738
Innate Immune System R-HSA-168249
RNA Polymerase II Transcription R-HSA-73857
Activation of the AP-1 family of transcription factors R-HSA-450341
Hemostasis R-HSA-109582
Neutrophil degranulation R-HSA-6798695
VEGFA-VEGFR2 Pathway R-HSA-4420097
Gene expression (Transcription) R-HSA-74160
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Netrin-1 signaling R-HSA-373752
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Cytokine Signaling in Immune system R-HSA-1280215
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Metabolism of RNA R-HSA-8953854
Generic Transcription Pathway R-HSA-212436
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular Senescence R-HSA-2559583
Interleukin-17 signaling R-HSA-448424
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by Interleukins R-HSA-449147
Platelet homeostasis R-HSA-418346
Mitochondrial biogenesis R-HSA-1592230
ERK/MAPK targets R-HSA-198753
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
p38MAPK events R-HSA-171007
Signal amplification R-HSA-392518
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Oxidative Stress Induced Senescence R-HSA-2559580
Transcriptional Regulation by TP53 R-HSA-3700989
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of TP53 Activity R-HSA-5633007
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
DSCAM interactions R-HSA-376172
MAP kinase activation R-HSA-450294
MyD88-independent TLR4 cascade R-HSA-166166
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Platelet sensitization by LDL R-HSA-432142
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Infectious disease R-HSA-5663205
Axon guidance R-HSA-422475
Leishmania infection R-HSA-9658195
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Signaling by Rho GTPases R-HSA-194315
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Disease R-HSA-1643685
Organelle biogenesis and maintenance R-HSA-1852241
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88 cascade initiated on plasma membrane R-HSA-975871
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Signalling to ERKs R-HSA-187687
CD163 mediating an anti-inflammatory response R-HSA-9662834
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by VEGF R-HSA-194138
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Developmental Biology R-HSA-1266738
Netrin-1 signaling R-HSA-373752
Immune System R-HSA-168256
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
DSCAM interactions R-HSA-376172
Toll-like Receptor Cascades R-HSA-168898
CD163 mediating an anti-inflammatory response R-HSA-9662834
Signaling by Rho GTPases R-HSA-194315
Platelet sensitization by LDL R-HSA-432142
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Mitochondrial biogenesis R-HSA-1592230
Platelet homeostasis R-HSA-418346
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Platelet activation, signaling and aggregation R-HSA-76002
Myogenesis R-HSA-525793
Organelle biogenesis and maintenance R-HSA-1852241
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
Signal Transduction R-HSA-162582
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Metabolism of RNA R-HSA-8953854
RHO GTPase Effectors R-HSA-195258
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Cytokine Signaling in Immune system R-HSA-1280215
Infectious disease R-HSA-5663205
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Signaling by VEGF R-HSA-194138
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MAP kinase activation R-HSA-450294
Signaling by Interleukins R-HSA-449147
Cellular Senescence R-HSA-2559583
Leishmania infection R-HSA-9658195
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Signaling by NTRK1 (TRKA) R-HSA-187037
Transcriptional Regulation by TP53 R-HSA-3700989
VEGFA-VEGFR2 Pathway R-HSA-4420097
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Signalling to RAS R-HSA-167044
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signalling to ERKs R-HSA-187687
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Hemostasis R-HSA-109582
RNA Polymerase II Transcription R-HSA-73857
Neutrophil degranulation R-HSA-6798695
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stimuli R-HSA-8953897
ERK/MAPK targets R-HSA-198753
p38MAPK events R-HSA-171007
Innate Immune System R-HSA-168249
Oxidative Stress Induced Senescence R-HSA-2559580
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by NTRKs R-HSA-166520
Leishmania parasite growth and survival R-HSA-9664433
NOD1/2 Signaling Pathway R-HSA-168638
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Regulation of TP53 Activity R-HSA-5633007
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Activation of the AP-1 family of transcription factors R-HSA-450341
Signal amplification R-HSA-392518
Nervous system development R-HSA-9675108
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 dependent cascade initiated on endosome R-HSA-975155
Interleukin-17 signaling R-HSA-448424
Signalling to ERKs R-HSA-187687
Myogenesis R-HSA-525793
VEGFA-VEGFR2 Pathway R-HSA-4420097
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
RNA Polymerase II Transcription R-HSA-73857
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signal amplification R-HSA-392518
NOD1/2 Signaling Pathway R-HSA-168638
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cellular responses to stress R-HSA-2262752
p38MAPK events R-HSA-171007
Cytokine Signaling in Immune system R-HSA-1280215
DSCAM interactions R-HSA-376172
MyD88 cascade initiated on plasma membrane R-HSA-975871
Disease R-HSA-1643685
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Netrin-1 signaling R-HSA-373752
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Neutrophil degranulation R-HSA-6798695
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Innate Immune System R-HSA-168249
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Platelet activation, signaling and aggregation R-HSA-76002
Signalling to RAS R-HSA-167044
MAP kinase activation R-HSA-450294
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Axon guidance R-HSA-422475
Leishmania infection R-HSA-9658195
Oxidative Stress Induced Senescence R-HSA-2559580
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by VEGF R-HSA-194138
Mitochondrial biogenesis R-HSA-1592230
Leishmania parasite growth and survival R-HSA-9664433
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
ERK/MAPK targets R-HSA-198753
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Activation of the AP-1 family of transcription factors R-HSA-450341
Platelet homeostasis R-HSA-418346
Signaling by Interleukins R-HSA-449147
RHO GTPase Effectors R-HSA-195258
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Hemostasis R-HSA-109582
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Infectious disease R-HSA-5663205
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity R-HSA-5633007
Signaling by NTRKs R-HSA-166520
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MyD88 dependent cascade initiated on endosome R-HSA-975155
CD163 mediating an anti-inflammatory response R-HSA-9662834
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Interleukin-17 signaling R-HSA-448424
Metabolism of RNA R-HSA-8953854
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Transcriptional Regulation by TP53 R-HSA-3700989
Platelet sensitization by LDL R-HSA-432142
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Immune System R-HSA-168256
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll-like Receptor Cascades R-HSA-168898
Developmental Biology R-HSA-1266738
Organelle biogenesis and maintenance R-HSA-1852241
Cellular responses to stimuli R-HSA-8953897
Nervous system development R-HSA-9675108
Mitochondrial biogenesis R-HSA-1592230
Leishmania parasite growth and survival R-HSA-9664433
Signalling to ERKs R-HSA-187687
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Developmental Biology R-HSA-1266738
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Platelet homeostasis R-HSA-418346
Neutrophil degranulation R-HSA-6798695
DSCAM interactions R-HSA-376172
Signal amplification R-HSA-392518
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular Senescence R-HSA-2559583
MyD88 cascade initiated on plasma membrane R-HSA-975871
RHO GTPase Effectors R-HSA-195258
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Platelet sensitization by LDL R-HSA-432142
RNA Polymerase II Transcription R-HSA-73857
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signal Transduction R-HSA-162582
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
CD163 mediating an anti-inflammatory response R-HSA-9662834
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Signaling by Rho GTPases R-HSA-194315
Signaling by NTRK1 (TRKA) R-HSA-187037
Interleukin-17 signaling R-HSA-448424
Cytokine Signaling in Immune system R-HSA-1280215
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Transcriptional Regulation by TP53 R-HSA-3700989
Myogenesis R-HSA-525793
Oxidative Stress Induced Senescence R-HSA-2559580
Hemostasis R-HSA-109582
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Innate Immune System R-HSA-168249
Nervous system development R-HSA-9675108
Leishmania infection R-HSA-9658195
Axon guidance R-HSA-422475
p38MAPK events R-HSA-171007
Signalling to RAS R-HSA-167044
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Activation of the AP-1 family of transcription factors R-HSA-450341
VEGFA-VEGFR2 Pathway R-HSA-4420097
MyD88-independent TLR4 cascade R-HSA-166166
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
MAP kinase activation R-HSA-450294
Regulation of TP53 Activity R-HSA-5633007
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Netrin-1 signaling R-HSA-373752
Immune System R-HSA-168256
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Cellular responses to stress R-HSA-2262752
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by NTRKs R-HSA-166520
Metabolism of RNA R-HSA-8953854
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Organelle biogenesis and maintenance R-HSA-1852241
NOD1/2 Signaling Pathway R-HSA-168638
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Signaling by VEGF R-HSA-194138
ERK/MAPK targets R-HSA-198753
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by Interleukins R-HSA-449147
Infectious disease R-HSA-5663205
Platelet activation, signaling and aggregation R-HSA-76002
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Interleukin-17 signaling R-HSA-448424
Immune System R-HSA-168256
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signal amplification R-HSA-392518
Transcriptional Regulation by TP53 R-HSA-3700989
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Organelle biogenesis and maintenance R-HSA-1852241
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MyD88 dependent cascade initiated on endosome R-HSA-975155
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
ERK/MAPK targets R-HSA-198753
Developmental Biology R-HSA-1266738
Mitochondrial biogenesis R-HSA-1592230
Platelet homeostasis R-HSA-418346
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signalling to RAS R-HSA-167044
Platelet sensitization by LDL R-HSA-432142
MAP kinase activation R-HSA-450294
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by Interleukins R-HSA-449147
RNA Polymerase II Transcription R-HSA-73857
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Rho GTPases R-HSA-194315
Signalling to ERKs R-HSA-187687
Toll-like Receptor Cascades R-HSA-168898
Cellular responses to stimuli R-HSA-8953897
Oxidative Stress Induced Senescence R-HSA-2559580
MyD88 cascade initiated on plasma membrane R-HSA-975871
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
MyD88-independent TLR4 cascade R-HSA-166166
Platelet activation, signaling and aggregation R-HSA-76002
Leishmania parasite growth and survival R-HSA-9664433
Myogenesis R-HSA-525793
activated TAK1 mediates p38 MAPK activation R-HSA-450302
p38MAPK events R-HSA-171007
Axon guidance R-HSA-422475
Cellular responses to stress R-HSA-2262752
Signaling by VEGF R-HSA-194138
DSCAM interactions R-HSA-376172
Netrin-1 signaling R-HSA-373752
VEGFA-VEGFR2 Pathway R-HSA-4420097
Leishmania infection R-HSA-9658195
Neutrophil degranulation R-HSA-6798695
Generic Transcription Pathway R-HSA-212436
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
CD163 mediating an anti-inflammatory response R-HSA-9662834
NOD1/2 Signaling Pathway R-HSA-168638
Hemostasis R-HSA-109582
Nervous system development R-HSA-9675108
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Cellular Senescence R-HSA-2559583
Signaling by NTRKs R-HSA-166520
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RHO GTPase Effectors R-HSA-195258
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Activation of the AP-1 family of transcription factors R-HSA-450341
Regulation of TP53 Activity R-HSA-5633007
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Metabolism of RNA R-HSA-8953854
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Infectious disease R-HSA-5663205
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of TP53 Activity R-HSA-5633007
Signalling to ERKs R-HSA-187687
Toll-like Receptor Cascades R-HSA-168898
Interleukin-17 signaling R-HSA-448424
Developmental Biology R-HSA-1266738
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Transcriptional Regulation by TP53 R-HSA-3700989
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Neutrophil degranulation R-HSA-6798695
Gene expression (Transcription) R-HSA-74160
CD163 mediating an anti-inflammatory response R-HSA-9662834
Oxidative Stress Induced Senescence R-HSA-2559580
Leishmania infection R-HSA-9658195
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Hemostasis R-HSA-109582
Axon guidance R-HSA-422475
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Signal Transduction R-HSA-162582
Myogenesis R-HSA-525793
Signal amplification R-HSA-392518
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by VEGF R-HSA-194138
Signaling by NTRKs R-HSA-166520
Generic Transcription Pathway R-HSA-212436
Activation of the AP-1 family of transcription factors R-HSA-450341
MyD88 dependent cascade initiated on endosome R-HSA-975155
Platelet homeostasis R-HSA-418346
Signaling by Interleukins R-HSA-449147
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Innate Immune System R-HSA-168249
p38MAPK events R-HSA-171007
Cellular Senescence R-HSA-2559583
Cellular responses to stress R-HSA-2262752
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Signaling by NTRK1 (TRKA) R-HSA-187037
Platelet activation, signaling and aggregation R-HSA-76002
activated TAK1 mediates p38 MAPK activation R-HSA-450302
NOD1/2 Signaling Pathway R-HSA-168638
Signalling to RAS R-HSA-167044
Nervous system development R-HSA-9675108
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
ERK/MAPK targets R-HSA-198753
Cytokine Signaling in Immune system R-HSA-1280215
DSCAM interactions R-HSA-376172
RHO GTPase Effectors R-HSA-195258
Immune System R-HSA-168256
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Netrin-1 signaling R-HSA-373752
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Organelle biogenesis and maintenance R-HSA-1852241
Mitochondrial biogenesis R-HSA-1592230
Leishmania parasite growth and survival R-HSA-9664433
MAP kinase activation R-HSA-450294
Signaling by Rho GTPases R-HSA-194315
Metabolism of RNA R-HSA-8953854
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Disease R-HSA-1643685
VEGFA-VEGFR2 Pathway R-HSA-4420097
Platelet sensitization by LDL R-HSA-432142
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MyD88 cascade initiated on plasma membrane R-HSA-975871
Disease R-HSA-1643685
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Developmental Biology R-HSA-1266738
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signal amplification R-HSA-392518
Signaling by VEGF R-HSA-194138
Metabolism of RNA R-HSA-8953854
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signaling by Interleukins R-HSA-449147
RHO GTPase Effectors R-HSA-195258
Transcriptional Regulation by TP53 R-HSA-3700989
Platelet activation, signaling and aggregation R-HSA-76002
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by NTRKs R-HSA-166520
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DSCAM interactions R-HSA-376172
Signal Transduction R-HSA-162582
Hemostasis R-HSA-109582
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MAP kinase activation R-HSA-450294
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Leishmania parasite growth and survival R-HSA-9664433
Mitochondrial biogenesis R-HSA-1592230
Signaling by NTRK1 (TRKA) R-HSA-187037
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Organelle biogenesis and maintenance R-HSA-1852241
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Interleukin-17 signaling R-HSA-448424
Nervous system development R-HSA-9675108
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulation of TP53 Activity R-HSA-5633007
Infectious disease R-HSA-5663205
Platelet homeostasis R-HSA-418346
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Signalling to RAS R-HSA-167044
MyD88-independent TLR4 cascade R-HSA-166166
Oxidative Stress Induced Senescence R-HSA-2559580
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Signaling by Rho GTPases R-HSA-194315
Leishmania infection R-HSA-9658195
Netrin-1 signaling R-HSA-373752
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Activation of the AP-1 family of transcription factors R-HSA-450341
Platelet sensitization by LDL R-HSA-432142
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Myogenesis R-HSA-525793
MyD88 dependent cascade initiated on endosome R-HSA-975155
VEGFA-VEGFR2 Pathway R-HSA-4420097
Gene expression (Transcription) R-HSA-74160
Cellular responses to stimuli R-HSA-8953897
CD163 mediating an anti-inflammatory response R-HSA-9662834
ERK/MAPK targets R-HSA-198753
NOD1/2 Signaling Pathway R-HSA-168638
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Toll-like Receptor Cascades R-HSA-168898
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
p38MAPK events R-HSA-171007
Signalling to ERKs R-HSA-187687
Signaling by VEGF R-HSA-194138
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
CD163 mediating an anti-inflammatory response R-HSA-9662834
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll-like Receptor Cascades R-HSA-168898
Infectious disease R-HSA-5663205
MyD88-independent TLR4 cascade R-HSA-166166
Netrin-1 signaling R-HSA-373752
Signaling by Interleukins R-HSA-449147
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Gene expression (Transcription) R-HSA-74160
Hemostasis R-HSA-109582
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MyD88 cascade initiated on plasma membrane R-HSA-975871
RNA Polymerase II Transcription R-HSA-73857
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Developmental Biology R-HSA-1266738
VEGFA-VEGFR2 Pathway R-HSA-4420097
Innate Immune System R-HSA-168249
Signalling to RAS R-HSA-167044
Transcriptional Regulation by TP53 R-HSA-3700989
Neutrophil degranulation R-HSA-6798695
RHO GTPase Effectors R-HSA-195258
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88 dependent cascade initiated on endosome R-HSA-975155
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Platelet homeostasis R-HSA-418346
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Metabolism of RNA R-HSA-8953854
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Leishmania infection R-HSA-9658195
Axon guidance R-HSA-422475
Mitochondrial biogenesis R-HSA-1592230
Signal amplification R-HSA-392518
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
ERK/MAPK targets R-HSA-198753
Cellular responses to stimuli R-HSA-8953897
Oxidative Stress Induced Senescence R-HSA-2559580
MAP kinase activation R-HSA-450294
Activation of the AP-1 family of transcription factors R-HSA-450341
Leishmania parasite growth and survival R-HSA-9664433
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Cellular Senescence R-HSA-2559583
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by NTRKs R-HSA-166520
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Platelet activation, signaling and aggregation R-HSA-76002
Myogenesis R-HSA-525793
Generic Transcription Pathway R-HSA-212436
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Immune System R-HSA-168256
Regulation of TP53 Activity R-HSA-5633007
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by NTRK1 (TRKA) R-HSA-187037
Organelle biogenesis and maintenance R-HSA-1852241
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signalling to ERKs R-HSA-187687
Cellular responses to stress R-HSA-2262752
p38MAPK events R-HSA-171007
DSCAM interactions R-HSA-376172
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
NOD1/2 Signaling Pathway R-HSA-168638
Nervous system development R-HSA-9675108
Platelet sensitization by LDL R-HSA-432142
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Interleukin-17 signaling R-HSA-448424
Signaling by Rho GTPases R-HSA-194315

Expression Atlas ENSG00000112062
NCBI gene (formerly Entrezgene) 1432
GeneCards 6876
HGNC Symbol HGNC:6876
MIM gene 600289
UniProtKB Gene Name Q16539
WikiGene 1432
Gene: AKT1
Ensembl ID : ENSG00000142208
Description: AKT serine/threonine kinase 1
Gene Synonyms: AKT,PKB,PRKBA,RAC,RAC-ALPHA
16 APIs:
220 Possible Orthologues:

Metabolism R-HSA-1430728
Immune System R-HSA-168256
Cell Cycle R-HSA-1640170
Signaling by GPCR R-HSA-372790
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Gene expression (Transcription) R-HSA-74160
Disease R-HSA-1643685
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular responses to stress R-HSA-2262752
VEGFA-VEGFR2 Pathway R-HSA-4420097
VEGFR2 mediated vascular permeability R-HSA-5218920
eNOS activation R-HSA-203615
CD28 co-stimulation R-HSA-389356
RUNX2 regulates genes involved in cell migration R-HSA-8941332
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
SARS-CoV Infections R-HSA-9679506
AKT phosphorylates targets in the nucleus R-HSA-198693
Metabolism of cofactors R-HSA-8978934
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Vesicle-mediated transport R-HSA-5653656
CD28 dependent PI3K/Akt signaling R-HSA-389357
Integrin signaling R-HSA-354192
Cellular response to chemical stress R-HSA-9711123
AKT-mediated inactivation of FOXO1A R-HSA-211163
Transcriptional Regulation by TP53 R-HSA-3700989
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle R-HSA-1640170
Programmed Cell Death R-HSA-5357801
Signaling by Nuclear Receptors R-HSA-9006931
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FOXO-mediated transcription R-HSA-9614085
Regulation of beta-cell development R-HSA-186712
S Phase R-HSA-69242
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Regulation of TP53 Activity R-HSA-5633007
Hemostasis R-HSA-109582
GPCR downstream signalling R-HSA-388396
Regulation of gene expression in beta cells R-HSA-210745
Generic Transcription Pathway R-HSA-212436
Mitotic G1 phase and G1/S transition R-HSA-453279
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by WNT R-HSA-195721
Regulation of PTEN stability and activity R-HSA-8948751
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Platelet activation, signaling and aggregation R-HSA-76002
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Signaling by GPCR R-HSA-372790
PIP3 activates AKT signaling R-HSA-1257604
Membrane Trafficking R-HSA-199991
Signaling by VEGF R-HSA-194138
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Metabolism of vitamins and cofactors R-HSA-196854
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
FLT3 Signaling R-HSA-9607240
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Extra-nuclear estrogen signaling R-HSA-9009391
SARS-CoV-2 Infection R-HSA-9694516
PTEN Regulation R-HSA-6807070
Signaling by PTK6 R-HSA-8848021
MTOR signalling R-HSA-165159
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
Intrinsic Pathway for Apoptosis R-HSA-109606
TP53 Regulates Metabolic Genes R-HSA-5628897
Rab regulation of trafficking R-HSA-9007101
Infectious disease R-HSA-5663205
Cell Cycle, Mitotic R-HSA-69278
Regulation of TP53 Degradation R-HSA-6804757
Regulation of localization of FOXO transcription factors R-HSA-9614399
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
Metabolism of RNA R-HSA-8953854
Platelet Aggregation (Plug Formation) R-HSA-76009
Activation of BAD and translocation to mitochondria R-HSA-111447
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
TCF dependent signaling in response to WNT R-HSA-201681
PI3K/AKT Signaling in Cancer R-HSA-2219528
Downregulation of ERBB2 signaling R-HSA-8863795
Regulation of TP53 Expression and Degradation R-HSA-6806003
G1/S Transition R-HSA-69206
Signaling by ERBB2 R-HSA-1227986
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
Cyclin E associated events during G1/S transition R-HSA-69202
CTLA4 inhibitory signaling R-HSA-389513
KEAP1-NFE2L2 pathway R-HSA-9755511
Apoptosis R-HSA-109581
ESR-mediated signaling R-HSA-8939211
Costimulation by the CD28 family R-HSA-388841
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
AKT phosphorylates targets in the cytosol R-HSA-198323
Developmental Biology R-HSA-1266738
G-protein beta:gamma signalling R-HSA-397795
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Activation of BH3-only proteins R-HSA-114452
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by NOTCH R-HSA-157118
Apoptosis R-HSA-109581
eNOS activation R-HSA-203615
KEAP1-NFE2L2 pathway R-HSA-9755511
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
PTEN Regulation R-HSA-6807070
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of TP53 Activity through Acetylation R-HSA-6804758
VEGFR2 mediated vascular permeability R-HSA-5218920
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Signaling by Nuclear Receptors R-HSA-9006931
Developmental Biology R-HSA-1266738
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
ESR-mediated signaling R-HSA-8939211
Regulation of TP53 Degradation R-HSA-6804757
Activation of BH3-only proteins R-HSA-114452
Intrinsic Pathway for Apoptosis R-HSA-109606
Rab regulation of trafficking R-HSA-9007101
AKT phosphorylates targets in the cytosol R-HSA-198323
Platelet Aggregation (Plug Formation) R-HSA-76009
Regulation of TP53 Expression and Degradation R-HSA-6806003
FLT3 Signaling R-HSA-9607240
Downregulation of ERBB2 signaling R-HSA-8863795
Costimulation by the CD28 family R-HSA-388841
Signaling by PTK6 R-HSA-8848021
G beta:gamma signalling through PI3Kgamma R-HSA-392451
SARS-CoV Infections R-HSA-9679506
Regulation of localization of FOXO transcription factors R-HSA-9614399
Cell Cycle, Mitotic R-HSA-69278
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
CD28 co-stimulation R-HSA-389356
Negative regulation of the PI3K/AKT network R-HSA-199418
TCF dependent signaling in response to WNT R-HSA-201681
Activation of BAD and translocation to mitochondria R-HSA-111447
PI3K/AKT Signaling in Cancer R-HSA-2219528
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Vesicle-mediated transport R-HSA-5653656
Cellular responses to stress R-HSA-2262752
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
Extra-nuclear estrogen signaling R-HSA-9009391
Integrin signaling R-HSA-354192
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Intracellular signaling by second messengers R-HSA-9006925
Cellular response to chemical stress R-HSA-9711123
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
VEGFA-VEGFR2 Pathway R-HSA-4420097
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Adaptive Immune System R-HSA-1280218
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SARS-CoV-2 Infection R-HSA-9694516
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
Signaling by ERBB2 R-HSA-1227986
FOXO-mediated transcription R-HSA-9614085
Transcriptional regulation by RUNX2 R-HSA-8878166
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Membrane Trafficking R-HSA-199991
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle R-HSA-1640170
Cyclin E associated events during G1/S transition R-HSA-69202
G-protein beta:gamma signalling R-HSA-397795
GPCR downstream signalling R-HSA-388396
Regulation of TP53 Activity R-HSA-5633007
S Phase R-HSA-69242
Signaling by VEGF R-HSA-194138
MTOR signalling R-HSA-165159
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
G1/S Transition R-HSA-69206
Programmed Cell Death R-HSA-5357801
Regulation of gene expression in beta cells R-HSA-210745
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
AKT-mediated inactivation of FOXO1A R-HSA-211163
Hemostasis R-HSA-109582
AKT phosphorylates targets in the nucleus R-HSA-198693
Infectious disease R-HSA-5663205
Metabolism of cofactors R-HSA-8978934
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
RNA Polymerase II Transcription R-HSA-73857
Metabolism of vitamins and cofactors R-HSA-196854
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by NOTCH4 R-HSA-9013694
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional Regulation by TP53 R-HSA-3700989
Cellular responses to stimuli R-HSA-8953897
TP53 Regulates Metabolic Genes R-HSA-5628897
Signaling by Interleukins R-HSA-449147
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Disease R-HSA-1643685
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
Immune System R-HSA-168256
Signaling by GPCR R-HSA-372790
Regulation of beta-cell development R-HSA-186712
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
CTLA4 inhibitory signaling R-HSA-389513
SARS-CoV-2-host interactions R-HSA-9705683
Metabolism of RNA R-HSA-8953854
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Regulation of TP53 Activity R-HSA-5633007
MTOR signalling R-HSA-165159
Signaling by NOTCH R-HSA-157118
Metabolism of vitamins and cofactors R-HSA-196854
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
VEGFR2 mediated vascular permeability R-HSA-5218920
Signal Transduction R-HSA-162582
Activation of BAD and translocation to mitochondria R-HSA-111447
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activation of BH3-only proteins R-HSA-114452
PTEN Regulation R-HSA-6807070
Transcriptional Regulation by TP53 R-HSA-3700989
Intrinsic Pathway for Apoptosis R-HSA-109606
ESR-mediated signaling R-HSA-8939211
Downregulation of ERBB2 signaling R-HSA-8863795
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
AKT phosphorylates targets in the nucleus R-HSA-198693
Signaling by Nuclear Receptors R-HSA-9006931
Adaptive Immune System R-HSA-1280218
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism R-HSA-1430728
CD28 co-stimulation R-HSA-389356
Developmental Biology R-HSA-1266738
Signaling by GPCR R-HSA-372790
Negative regulation of the PI3K/AKT network R-HSA-199418
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
S Phase R-HSA-69242
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stimuli R-HSA-8953897
Metabolism of RNA R-HSA-8953854
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
Regulation of TP53 Degradation R-HSA-6804757
Immune System R-HSA-168256
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
SARS-CoV Infections R-HSA-9679506
G-protein beta:gamma signalling R-HSA-397795
Signaling by WNT R-HSA-195721
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Transcriptional regulation by RUNX2 R-HSA-8878166
Platelet activation, signaling and aggregation R-HSA-76002
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by Interleukins R-HSA-449147
Apoptosis R-HSA-109581
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of beta-cell development R-HSA-186712
Cellular responses to stress R-HSA-2262752
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Hemostasis R-HSA-109582
Cell Cycle, Mitotic R-HSA-69278
GPCR downstream signalling R-HSA-388396
Vesicle-mediated transport R-HSA-5653656
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
FLT3 Signaling R-HSA-9607240
AKT-mediated inactivation of FOXO1A R-HSA-211163
Costimulation by the CD28 family R-HSA-388841
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of gene expression in beta cells R-HSA-210745
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by ERBB2 R-HSA-1227986
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by PTK6 R-HSA-8848021
Mitotic G1 phase and G1/S transition R-HSA-453279
Cytokine Signaling in Immune system R-HSA-1280215
Integrin signaling R-HSA-354192
G1/S Transition R-HSA-69206
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Signaling by NOTCH4 R-HSA-9013694
Membrane Trafficking R-HSA-199991
CTLA4 inhibitory signaling R-HSA-389513
Regulation of PTEN stability and activity R-HSA-8948751
AKT phosphorylates targets in the cytosol R-HSA-198323
CD28 dependent PI3K/Akt signaling R-HSA-389357
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Extra-nuclear estrogen signaling R-HSA-9009391
Generic Transcription Pathway R-HSA-212436
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Intracellular signaling by second messengers R-HSA-9006925
Signaling by VEGF R-HSA-194138
FOXO-mediated transcription R-HSA-9614085
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
eNOS activation R-HSA-203615
SARS-CoV-2 Infection R-HSA-9694516
Platelet Aggregation (Plug Formation) R-HSA-76009
Cellular response to chemical stress R-HSA-9711123
TP53 Regulates Metabolic Genes R-HSA-5628897
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Programmed Cell Death R-HSA-5357801
Metabolism of cofactors R-HSA-8978934
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Regulation of localization of FOXO transcription factors R-HSA-9614399
VEGFA-VEGFR2 Pathway R-HSA-4420097
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Expression and Degradation R-HSA-6806003
Rab regulation of trafficking R-HSA-9007101
PIP3 activates AKT signaling R-HSA-1257604
VEGFA-VEGFR2 Pathway R-HSA-4420097
Vesicle-mediated transport R-HSA-5653656
Regulation of TP53 Activity R-HSA-5633007
TP53 Regulates Metabolic Genes R-HSA-5628897
SARS-CoV Infections R-HSA-9679506
PIP3 activates AKT signaling R-HSA-1257604
PI3K/AKT Signaling in Cancer R-HSA-2219528
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
SARS-CoV-2-host interactions R-HSA-9705683
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
ESR-mediated signaling R-HSA-8939211
Platelet Aggregation (Plug Formation) R-HSA-76009
Rab regulation of trafficking R-HSA-9007101
Signaling by NOTCH4 R-HSA-9013694
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Metabolism of vitamins and cofactors R-HSA-196854
Signaling by PTK6 R-HSA-8848021
Generic Transcription Pathway R-HSA-212436
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
eNOS activation R-HSA-203615
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by WNT R-HSA-195721
Intracellular signaling by second messengers R-HSA-9006925
PTEN Regulation R-HSA-6807070
Signaling by Nuclear Receptors R-HSA-9006931
CD28 co-stimulation R-HSA-389356
SARS-CoV-2 Infection R-HSA-9694516
Adaptive Immune System R-HSA-1280218
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
AKT phosphorylates targets in the nucleus R-HSA-198693
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Programmed Cell Death R-HSA-5357801
Activation of BH3-only proteins R-HSA-114452
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cellular response to chemical stress R-HSA-9711123
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH R-HSA-157118
Signaling by VEGF R-HSA-194138
AKT-mediated inactivation of FOXO1A R-HSA-211163
GPCR downstream signalling R-HSA-388396
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Degradation R-HSA-6804757
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
CTLA4 inhibitory signaling R-HSA-389513
Regulation of PTEN stability and activity R-HSA-8948751
Activation of BAD and translocation to mitochondria R-HSA-111447
Platelet activation, signaling and aggregation R-HSA-76002
Cell Cycle R-HSA-1640170
G-protein beta:gamma signalling R-HSA-397795
Signaling by ERBB2 R-HSA-1227986
Disease R-HSA-1643685
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Signal Transduction R-HSA-162582
VEGFR2 mediated vascular permeability R-HSA-5218920
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by GPCR R-HSA-372790
Costimulation by the CD28 family R-HSA-388841
Regulation of beta-cell development R-HSA-186712
Regulation of gene expression in beta cells R-HSA-210745
Regulation of localization of FOXO transcription factors R-HSA-9614399
G1/S Transition R-HSA-69206
Infectious disease R-HSA-5663205
Negative regulation of NOTCH4 signaling R-HSA-9604323
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Metabolism of RNA R-HSA-8953854
Cellular responses to stimuli R-HSA-8953897
Apoptosis R-HSA-109581
AKT phosphorylates targets in the cytosol R-HSA-198323
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
S Phase R-HSA-69242
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Cellular responses to stress R-HSA-2262752
Integrin signaling R-HSA-354192
Extra-nuclear estrogen signaling R-HSA-9009391
Downregulation of ERBB2 signaling R-HSA-8863795
Metabolism of cofactors R-HSA-8978934
FOXO-mediated transcription R-HSA-9614085
Negative regulation of the PI3K/AKT network R-HSA-199418
Hemostasis R-HSA-109582
Cell Cycle, Mitotic R-HSA-69278
Gene expression (Transcription) R-HSA-74160
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Membrane Trafficking R-HSA-199991
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
CD28 dependent PI3K/Akt signaling R-HSA-389357
MTOR signalling R-HSA-165159
FLT3 Signaling R-HSA-9607240
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by PTK6 R-HSA-8848021
Cellular response to chemical stress R-HSA-9711123
Signaling by VEGF R-HSA-194138
Cell Cycle, Mitotic R-HSA-69278
Regulation of localization of FOXO transcription factors R-HSA-9614399
Signaling by Interleukins R-HSA-449147
Negative regulation of NOTCH4 signaling R-HSA-9604323
MTOR signalling R-HSA-165159
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Adaptive Immune System R-HSA-1280218
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Programmed Cell Death R-HSA-5357801
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of TP53 Activity R-HSA-5633007
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intrinsic Pathway for Apoptosis R-HSA-109606
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
CD28 co-stimulation R-HSA-389356
TP53 Regulates Metabolic Genes R-HSA-5628897
Apoptosis R-HSA-109581
Regulation of gene expression in beta cells R-HSA-210745
AKT-mediated inactivation of FOXO1A R-HSA-211163
Cytokine Signaling in Immune system R-HSA-1280215
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
ESR-mediated signaling R-HSA-8939211
Mitotic G1 phase and G1/S transition R-HSA-453279
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Downregulation of ERBB2 signaling R-HSA-8863795
Signaling by NOTCH R-HSA-157118
VEGFR2 mediated vascular permeability R-HSA-5218920
Signaling by ERBB2 R-HSA-1227986
Activation of BH3-only proteins R-HSA-114452
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
G-protein beta:gamma signalling R-HSA-397795
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by NOTCH4 R-HSA-9013694
Platelet Aggregation (Plug Formation) R-HSA-76009
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism R-HSA-1430728
Transcriptional Regulation by TP53 R-HSA-3700989
AKT phosphorylates targets in the nucleus R-HSA-198693
Integrin signaling R-HSA-354192
Activation of BAD and translocation to mitochondria R-HSA-111447
eNOS activation R-HSA-203615
FLT3 Signaling R-HSA-9607240
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of beta-cell development R-HSA-186712
Signaling by Nuclear Receptors R-HSA-9006931
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
KEAP1-NFE2L2 pathway R-HSA-9755511
G1/S Transition R-HSA-69206
Negative regulation of the PI3K/AKT network R-HSA-199418
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cellular responses to stimuli R-HSA-8953897
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
SARS-CoV Infections R-HSA-9679506
Signaling by GPCR R-HSA-372790
SARS-CoV-2-host interactions R-HSA-9705683
Costimulation by the CD28 family R-HSA-388841
Metabolism of RNA R-HSA-8953854
CD28 dependent PI3K/Akt signaling R-HSA-389357
TCF dependent signaling in response to WNT R-HSA-201681
Immune System R-HSA-168256
VEGFA-VEGFR2 Pathway R-HSA-4420097
Regulation of TP53 Activity through Acetylation R-HSA-6804758
PI3K/AKT Signaling in Cancer R-HSA-2219528
SARS-CoV-2 Infection R-HSA-9694516
Metabolism of cofactors R-HSA-8978934
GPCR downstream signalling R-HSA-388396
AKT phosphorylates targets in the cytosol R-HSA-198323
S Phase R-HSA-69242
Rab regulation of trafficking R-HSA-9007101
Platelet activation, signaling and aggregation R-HSA-76002
FOXO-mediated transcription R-HSA-9614085
Vesicle-mediated transport R-HSA-5653656
Generic Transcription Pathway R-HSA-212436
G beta:gamma signalling through PI3Kgamma R-HSA-392451
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
PIP3 activates AKT signaling R-HSA-1257604
Infectious disease R-HSA-5663205
Metabolism of vitamins and cofactors R-HSA-196854
Hemostasis R-HSA-109582
Membrane Trafficking R-HSA-199991
CTLA4 inhibitory signaling R-HSA-389513
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Developmental Biology R-HSA-1266738
Regulation of TP53 Degradation R-HSA-6804757
Cell Cycle, Mitotic R-HSA-69278
Cyclin E associated events during G1/S transition R-HSA-69202
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disease R-HSA-1643685
Downregulation of ERBB2 signaling R-HSA-8863795
Activation of BAD and translocation to mitochondria R-HSA-111447
Signaling by Interleukins R-HSA-449147
Regulation of localization of FOXO transcription factors R-HSA-9614399
AKT phosphorylates targets in the cytosol R-HSA-198323
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
AKT phosphorylates targets in the nucleus R-HSA-198693
Hemostasis R-HSA-109582
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Platelet activation, signaling and aggregation R-HSA-76002
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Signaling by PTK6 R-HSA-8848021
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
G1/S Transition R-HSA-69206
FLT3 Signaling R-HSA-9607240
Transcriptional Regulation by TP53 R-HSA-3700989
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
CTLA4 inhibitory signaling R-HSA-389513
TCF dependent signaling in response to WNT R-HSA-201681
Platelet Aggregation (Plug Formation) R-HSA-76009
CD28 dependent PI3K/Akt signaling R-HSA-389357
PTEN Regulation R-HSA-6807070
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Activation of BH3-only proteins R-HSA-114452
Membrane Trafficking R-HSA-199991
Signaling by NOTCH R-HSA-157118
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Rab regulation of trafficking R-HSA-9007101
Regulation of PTEN stability and activity R-HSA-8948751
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by GPCR R-HSA-372790
Vesicle-mediated transport R-HSA-5653656
Metabolism of vitamins and cofactors R-HSA-196854
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGFA-VEGFR2 Pathway R-HSA-4420097
Metabolism of cofactors R-HSA-8978934
eNOS activation R-HSA-203615
Cellular response to chemical stress R-HSA-9711123
SARS-CoV Infections R-HSA-9679506
PIP3 activates AKT signaling R-HSA-1257604
Regulation of TP53 Degradation R-HSA-6804757
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulation of TP53 Activity through Acetylation R-HSA-6804758
TP53 Regulates Metabolic Genes R-HSA-5628897
VEGFR2 mediated vascular permeability R-HSA-5218920
Infectious disease R-HSA-5663205
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Cell Cycle R-HSA-1640170
Cellular responses to stress R-HSA-2262752
MTOR signalling R-HSA-165159
Programmed Cell Death R-HSA-5357801
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Regulation of beta-cell development R-HSA-186712
CD28 co-stimulation R-HSA-389356
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Immune System R-HSA-168256
PI3K/AKT Signaling in Cancer R-HSA-2219528
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by NOTCH4 R-HSA-9013694
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Intracellular signaling by second messengers R-HSA-9006925
SARS-CoV-2 Infection R-HSA-9694516
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of TP53 Expression and Degradation R-HSA-6806003
Generic Transcription Pathway R-HSA-212436
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
FOXO-mediated transcription R-HSA-9614085
Integrin signaling R-HSA-354192
Metabolism of RNA R-HSA-8953854
Regulation of TP53 Activity R-HSA-5633007
Signaling by Nuclear Receptors R-HSA-9006931
Extra-nuclear estrogen signaling R-HSA-9009391
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Metabolism R-HSA-1430728
Signaling by ERBB2 R-HSA-1227986
Regulation of gene expression in beta cells R-HSA-210745
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX2 R-HSA-8878166
S Phase R-HSA-69242
G-protein beta:gamma signalling R-HSA-397795
Signal Transduction R-HSA-162582
KEAP1-NFE2L2 pathway R-HSA-9755511
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
Signaling by VEGF R-HSA-194138
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Signaling by WNT R-HSA-195721
AKT-mediated inactivation of FOXO1A R-HSA-211163
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
GPCR downstream signalling R-HSA-388396
Cellular responses to stimuli R-HSA-8953897
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Costimulation by the CD28 family R-HSA-388841
ESR-mediated signaling R-HSA-8939211
TCF dependent signaling in response to WNT R-HSA-201681
ESR-mediated signaling R-HSA-8939211
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Programmed Cell Death R-HSA-5357801
Signaling by Interleukins R-HSA-449147
SARS-CoV-2-host interactions R-HSA-9705683
Intrinsic Pathway for Apoptosis R-HSA-109606
VEGFR2 mediated vascular permeability R-HSA-5218920
Regulation of gene expression in beta cells R-HSA-210745
CD28 co-stimulation R-HSA-389356
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Hemostasis R-HSA-109582
Metabolism R-HSA-1430728
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by NOTCH R-HSA-157118
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
Platelet Aggregation (Plug Formation) R-HSA-76009
G1/S Transition R-HSA-69206
Metabolism of cofactors R-HSA-8978934
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH4 R-HSA-9013694
Immune System R-HSA-168256
PTEN Regulation R-HSA-6807070
VEGFA-VEGFR2 Pathway R-HSA-4420097
Regulation of TP53 Activity R-HSA-5633007
Transcriptional regulation by RUNX2 R-HSA-8878166
Membrane Trafficking R-HSA-199991
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
CTLA4 inhibitory signaling R-HSA-389513
TP53 Regulates Metabolic Genes R-HSA-5628897
Regulation of beta-cell development R-HSA-186712
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
AKT phosphorylates targets in the cytosol R-HSA-198323
eNOS activation R-HSA-203615
Costimulation by the CD28 family R-HSA-388841
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Activation of BAD and translocation to mitochondria R-HSA-111447
SARS-CoV-2 Infection R-HSA-9694516
Apoptosis R-HSA-109581
CD28 dependent PI3K/Akt signaling R-HSA-389357
Metabolism of RNA R-HSA-8953854
Regulation of TP53 Degradation R-HSA-6804757
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Cellular responses to stimuli R-HSA-8953897
Downregulation of ERBB2 signaling R-HSA-8863795
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
Signaling by ERBB2 R-HSA-1227986
Regulation of TP53 Expression and Degradation R-HSA-6806003
Mitotic G1 phase and G1/S transition R-HSA-453279
Disease R-HSA-1643685
Cellular response to chemical stress R-HSA-9711123
Generic Transcription Pathway R-HSA-212436
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
AKT phosphorylates targets in the nucleus R-HSA-198693
MTOR signalling R-HSA-165159
Regulation of localization of FOXO transcription factors R-HSA-9614399
SARS-CoV Infections R-HSA-9679506
S Phase R-HSA-69242
Intracellular signaling by second messengers R-HSA-9006925
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Signal Transduction R-HSA-162582
Extra-nuclear estrogen signaling R-HSA-9009391
FOXO-mediated transcription R-HSA-9614085
Developmental Biology R-HSA-1266738
Cyclin E associated events during G1/S transition R-HSA-69202
RNA Polymerase II Transcription R-HSA-73857
FLT3 Signaling R-HSA-9607240
Infectious disease R-HSA-5663205
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Cell Cycle R-HSA-1640170
Rab regulation of trafficking R-HSA-9007101
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
PI3K/AKT Signaling in Cancer R-HSA-2219528
GPCR downstream signalling R-HSA-388396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional Regulation by TP53 R-HSA-3700989
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cell Cycle, Mitotic R-HSA-69278
Signaling by VEGF R-HSA-194138
Platelet activation, signaling and aggregation R-HSA-76002
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Signaling by PTK6 R-HSA-8848021
Metabolism of vitamins and cofactors R-HSA-196854
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Regulation of PTEN stability and activity R-HSA-8948751
Vesicle-mediated transport R-HSA-5653656
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Signaling by Nuclear Receptors R-HSA-9006931
Negative regulation of NOTCH4 signaling R-HSA-9604323
G-protein beta:gamma signalling R-HSA-397795
AKT-mediated inactivation of FOXO1A R-HSA-211163
Activation of BH3-only proteins R-HSA-114452
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by WNT R-HSA-195721
Adaptive Immune System R-HSA-1280218
Integrin signaling R-HSA-354192
PIP3 activates AKT signaling R-HSA-1257604
KEAP1-NFE2L2 pathway R-HSA-9755511
Cytokine Signaling in Immune system R-HSA-1280215
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
Signaling by NOTCH4 R-HSA-9013694
Vesicle-mediated transport R-HSA-5653656
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
S Phase R-HSA-69242
Transcriptional Regulation by TP53 R-HSA-3700989
ESR-mediated signaling R-HSA-8939211
VEGFR2 mediated vascular permeability R-HSA-5218920
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Platelet activation, signaling and aggregation R-HSA-76002
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Signaling by Nuclear Receptors R-HSA-9006931
Negative regulation of NOTCH4 signaling R-HSA-9604323
eNOS activation R-HSA-203615
Cell Cycle, Mitotic R-HSA-69278
Adaptive Immune System R-HSA-1280218
Membrane Trafficking R-HSA-199991
Hemostasis R-HSA-109582
Negative regulation of the PI3K/AKT network R-HSA-199418
Regulation of PTEN stability and activity R-HSA-8948751
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Integrin signaling R-HSA-354192
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Intracellular signaling by second messengers R-HSA-9006925
Regulation of TP53 Degradation R-HSA-6804757
G1/S Transition R-HSA-69206
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
SARS-CoV-2 Infection R-HSA-9694516
Signaling by PTK6 R-HSA-8848021
Downregulation of ERBB2 signaling R-HSA-8863795
Intrinsic Pathway for Apoptosis R-HSA-109606
Cellular responses to stress R-HSA-2262752
Regulation of beta-cell development R-HSA-186712
MTOR signalling R-HSA-165159
Signaling by ERBB2 R-HSA-1227986
PI3K/AKT Signaling in Cancer R-HSA-2219528
PTEN Regulation R-HSA-6807070
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by GPCR R-HSA-372790
Regulation of gene expression in beta cells R-HSA-210745
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
RNA Polymerase II Transcription R-HSA-73857
Activation of BAD and translocation to mitochondria R-HSA-111447
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of RNA R-HSA-8953854
AKT phosphorylates targets in the cytosol R-HSA-198323
G-protein beta:gamma signalling R-HSA-397795
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Apoptosis R-HSA-109581
Cellular responses to stimuli R-HSA-8953897
TP53 Regulates Metabolic Genes R-HSA-5628897
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
FLT3 Signaling R-HSA-9607240
Extra-nuclear estrogen signaling R-HSA-9009391
GPCR downstream signalling R-HSA-388396
CTLA4 inhibitory signaling R-HSA-389513
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of TP53 Activity R-HSA-5633007
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle R-HSA-1640170
CD28 dependent PI3K/Akt signaling R-HSA-389357
AKT phosphorylates targets in the nucleus R-HSA-198693
CD28 co-stimulation R-HSA-389356
VEGFA-VEGFR2 Pathway R-HSA-4420097
Activation of BH3-only proteins R-HSA-114452
Signaling by VEGF R-HSA-194138
Rab regulation of trafficking R-HSA-9007101
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
SARS-CoV Infections R-HSA-9679506
Platelet Aggregation (Plug Formation) R-HSA-76009
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Cellular response to chemical stress R-HSA-9711123
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by NOTCH R-HSA-157118
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Metabolism R-HSA-1430728
Developmental Biology R-HSA-1266738
Costimulation by the CD28 family R-HSA-388841
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Generic Transcription Pathway R-HSA-212436
Programmed Cell Death R-HSA-5357801
AKT-mediated inactivation of FOXO1A R-HSA-211163
Signaling by Interleukins R-HSA-449147
Signaling by WNT R-HSA-195721
Infectious disease R-HSA-5663205
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulation of localization of FOXO transcription factors R-HSA-9614399
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic G1 phase and G1/S transition R-HSA-453279
FOXO-mediated transcription R-HSA-9614085
Regulation of TP53 Expression and Degradation R-HSA-6806003
Metabolism of cofactors R-HSA-8978934
Metabolism of vitamins and cofactors R-HSA-196854
Immune System R-HSA-168256
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
AKT phosphorylates targets in the cytosol R-HSA-198323
PIP3 activates AKT signaling R-HSA-1257604
VEGFA-VEGFR2 Pathway R-HSA-4420097
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Activation of BH3-only proteins R-HSA-114452
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Programmed Cell Death R-HSA-5357801
Activation of BAD and translocation to mitochondria R-HSA-111447
Signaling by VEGF R-HSA-194138
G-protein beta:gamma signalling R-HSA-397795
Cellular responses to stress R-HSA-2262752
Vesicle-mediated transport R-HSA-5653656
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Regulation of gene expression in beta cells R-HSA-210745
Intracellular signaling by second messengers R-HSA-9006925
Platelet activation, signaling and aggregation R-HSA-76002
Gene expression (Transcription) R-HSA-74160
CD28 dependent PI3K/Akt signaling R-HSA-389357
Metabolism of RNA R-HSA-8953854
Integrin signaling R-HSA-354192
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
CTLA4 inhibitory signaling R-HSA-389513
Signaling by Nuclear Receptors R-HSA-9006931
eNOS activation R-HSA-203615
Regulation of PTEN stability and activity R-HSA-8948751
Adaptive Immune System R-HSA-1280218
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Apoptosis R-HSA-109581
Infectious disease R-HSA-5663205
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
SARS-CoV-2 Infection R-HSA-9694516
Signaling by GPCR R-HSA-372790
KEAP1-NFE2L2 pathway R-HSA-9755511
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of TP53 Expression and Degradation R-HSA-6806003
SARS-CoV Infections R-HSA-9679506
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Regulation of localization of FOXO transcription factors R-HSA-9614399
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Metabolism R-HSA-1430728
Disease R-HSA-1643685
FLT3 Signaling R-HSA-9607240
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Intrinsic Pathway for Apoptosis R-HSA-109606
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by NOTCH4 R-HSA-9013694
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
PI3K/AKT Signaling in Cancer R-HSA-2219528
ESR-mediated signaling R-HSA-8939211
TP53 Regulates Metabolic Genes R-HSA-5628897
Rab regulation of trafficking R-HSA-9007101
FOXO-mediated transcription R-HSA-9614085
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Metabolism of cofactors R-HSA-8978934
CD28 co-stimulation R-HSA-389356
Costimulation by the CD28 family R-HSA-388841
Membrane Trafficking R-HSA-199991
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
AKT-mediated inactivation of FOXO1A R-HSA-211163
Generic Transcription Pathway R-HSA-212436
S Phase R-HSA-69242
Downregulation of ERBB2 signaling R-HSA-8863795
Transcriptional regulation by RUNX2 R-HSA-8878166
Negative regulation of the PI3K/AKT network R-HSA-199418
G1/S Transition R-HSA-69206
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by ERBB2 R-HSA-1227986
Mitotic G1 phase and G1/S transition R-HSA-453279
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Transcriptional Regulation by TP53 R-HSA-3700989
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Metabolism of vitamins and cofactors R-HSA-196854
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Signal Transduction R-HSA-162582
MTOR signalling R-HSA-165159
Regulation of beta-cell development R-HSA-186712
Immune System R-HSA-168256
Platelet Aggregation (Plug Formation) R-HSA-76009
Signaling by PTK6 R-HSA-8848021
VEGFR2 mediated vascular permeability R-HSA-5218920
Cellular response to chemical stress R-HSA-9711123
Extra-nuclear estrogen signaling R-HSA-9009391
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
GPCR downstream signalling R-HSA-388396
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
RNA Polymerase II Transcription R-HSA-73857
Signaling by WNT R-HSA-195721
Developmental Biology R-HSA-1266738
PTEN Regulation R-HSA-6807070
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Interleukins R-HSA-449147
SARS-CoV-2-host interactions R-HSA-9705683
Hemostasis R-HSA-109582
AKT phosphorylates targets in the nucleus R-HSA-198693
Regulation of TP53 Degradation R-HSA-6804757
G beta:gamma signalling through PI3Kgamma R-HSA-392451

Expression Atlas ENSG00000142208
LRG display in Ensembl gene LRG_721
NCBI gene (formerly Entrezgene) 207
GeneCards 391
HGNC Symbol HGNC:391
MIM gene 164730
MIM morbid 615109
UniProtKB Gene Name P31749
WikiGene 207
Gene: CHEK2
Ensembl ID : ENSG00000183765
Description: checkpoint kinase 2
Gene Synonyms: BA444G7,CDS1,CHK2,HUCDS1,PP1425,RAD53
2 APIs:
206 Possible Orthologues:

Regulation of TP53 Activity R-HSA-5633007
DNA Repair R-HSA-73894
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Regulation of TP53 Degradation R-HSA-6804757
DNA Double Strand Break Response R-HSA-5693606
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
DNA Double-Strand Break Repair R-HSA-5693532
RNA Polymerase II Transcription R-HSA-73857
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of TP53 Expression and Degradation R-HSA-6806003
G2/M Checkpoints R-HSA-69481
Regulation of TP53 Activity through Methylation R-HSA-6804760
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cell Cycle Checkpoints R-HSA-69620
p53-Dependent G1 DNA Damage Response R-HSA-69563
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by TP53 R-HSA-3700989
Stabilization of p53 R-HSA-69541
G2/M DNA damage checkpoint R-HSA-69473
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle Checkpoints R-HSA-69620
G2/M DNA damage checkpoint R-HSA-69473
Cell Cycle R-HSA-1640170
p53-Independent DNA Damage Response R-HSA-69610
G2/M Checkpoints R-HSA-69481
Transcriptional Regulation by TP53 R-HSA-3700989
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Repair R-HSA-73894
Regulation of TP53 Degradation R-HSA-6804757
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Generic Transcription Pathway R-HSA-212436
Stabilization of p53 R-HSA-69541
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S DNA Damage Checkpoints R-HSA-69615
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Regulation of TP53 Activity R-HSA-5633007
DNA Double Strand Break Response R-HSA-5693606
Regulation of TP53 Expression and Degradation R-HSA-6806003
DNA Double-Strand Break Repair R-HSA-5693532
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity through Methylation R-HSA-6804760
Regulation of TP53 Degradation R-HSA-6804757
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle Checkpoints R-HSA-69620
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Repair R-HSA-73894
G2/M Checkpoints R-HSA-69481
Regulation of TP53 Activity through Methylation R-HSA-6804760
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of TP53 Activity R-HSA-5633007
DNA Double Strand Break Response R-HSA-5693606
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Regulation of TP53 Expression and Degradation R-HSA-6806003
RNA Polymerase II Transcription R-HSA-73857
Stabilization of p53 R-HSA-69541
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by TP53 R-HSA-3700989
DNA Double-Strand Break Repair R-HSA-5693532
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Gene expression (Transcription) R-HSA-74160
Cell Cycle R-HSA-1640170
G2/M DNA damage checkpoint R-HSA-69473
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Generic Transcription Pathway R-HSA-212436
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
G2/M DNA damage checkpoint R-HSA-69473
G2/M Checkpoints R-HSA-69481
Cell Cycle Checkpoints R-HSA-69620
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Independent DNA Damage Response R-HSA-69610
Regulation of TP53 Activity through Methylation R-HSA-6804760
p53-Dependent G1 DNA Damage Response R-HSA-69563
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity R-HSA-5633007
Regulation of TP53 Degradation R-HSA-6804757
Cell Cycle R-HSA-1640170
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Regulation of TP53 Expression and Degradation R-HSA-6806003
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Double Strand Break Response R-HSA-5693606
Stabilization of p53 R-HSA-69541
RNA Polymerase II Transcription R-HSA-73857
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Double-Strand Break Repair R-HSA-5693532
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Transcriptional Regulation by TP53 R-HSA-3700989
DNA Repair R-HSA-73894
DNA Repair R-HSA-73894
G2/M Checkpoints R-HSA-69481
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cell Cycle Checkpoints R-HSA-69620
DNA Double Strand Break Response R-HSA-5693606
Cell Cycle R-HSA-1640170
G2/M DNA damage checkpoint R-HSA-69473
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of TP53 Activity R-HSA-5633007
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
DNA Double-Strand Break Repair R-HSA-5693532
Transcriptional Regulation by TP53 R-HSA-3700989
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Regulation of TP53 Degradation R-HSA-6804757
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Methylation R-HSA-6804760
RNA Polymerase II Transcription R-HSA-73857
p53-Independent DNA Damage Response R-HSA-69610
Stabilization of p53 R-HSA-69541
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional Regulation by TP53 R-HSA-3700989
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle Checkpoints R-HSA-69620
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Expression and Degradation R-HSA-6806003
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of TP53 Activity through Methylation R-HSA-6804760
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Regulation of TP53 Activity R-HSA-5633007
DNA Repair R-HSA-73894
Cell Cycle R-HSA-1640170
DNA Double-Strand Break Repair R-HSA-5693532
Stabilization of p53 R-HSA-69541
DNA Double Strand Break Response R-HSA-5693606
p53-Independent DNA Damage Response R-HSA-69610
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Generic Transcription Pathway R-HSA-212436
G2/M DNA damage checkpoint R-HSA-69473
RNA Polymerase II Transcription R-HSA-73857
G2/M Checkpoints R-HSA-69481
DNA Double Strand Break Response R-HSA-5693606
Transcriptional Regulation by TP53 R-HSA-3700989
Cell Cycle R-HSA-1640170
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Regulation of TP53 Activity through Methylation R-HSA-6804760
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
G2/M DNA damage checkpoint R-HSA-69473
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Expression and Degradation R-HSA-6806003
Regulation of TP53 Degradation R-HSA-6804757
RNA Polymerase II Transcription R-HSA-73857
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Regulation of TP53 Activity R-HSA-5633007
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Repair R-HSA-73894
Generic Transcription Pathway R-HSA-212436
Stabilization of p53 R-HSA-69541
Cell Cycle Checkpoints R-HSA-69620
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G2/M Checkpoints R-HSA-69481
DNA Double-Strand Break Repair R-HSA-5693532
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Independent DNA Damage Response R-HSA-69610
Stabilization of p53 R-HSA-69541
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cell Cycle R-HSA-1640170
Transcriptional Regulation by TP53 R-HSA-3700989
DNA Double-Strand Break Repair R-HSA-5693532
G2/M Checkpoints R-HSA-69481
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Regulation of TP53 Activity through Methylation R-HSA-6804760
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Dependent G1 DNA Damage Response R-HSA-69563
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Degradation R-HSA-6804757
DNA Repair R-HSA-73894
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
G2/M DNA damage checkpoint R-HSA-69473
Regulation of TP53 Activity R-HSA-5633007
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Independent DNA Damage Response R-HSA-69610
DNA Double Strand Break Response R-HSA-5693606
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle Checkpoints R-HSA-69620
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Double Strand Break Response R-HSA-5693606
Regulation of TP53 Activity through Methylation R-HSA-6804760
Transcriptional Regulation by TP53 R-HSA-3700989
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle R-HSA-1640170
G2/M DNA damage checkpoint R-HSA-69473
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Independent DNA Damage Response R-HSA-69610
G2/M Checkpoints R-HSA-69481
Generic Transcription Pathway R-HSA-212436
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity R-HSA-5633007
RNA Polymerase II Transcription R-HSA-73857
DNA Repair R-HSA-73894
Regulation of TP53 Expression and Degradation R-HSA-6806003
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Double-Strand Break Repair R-HSA-5693532
Stabilization of p53 R-HSA-69541
G1/S DNA Damage Checkpoints R-HSA-69615
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
G2/M DNA damage checkpoint R-HSA-69473
Stabilization of p53 R-HSA-69541
Regulation of TP53 Activity R-HSA-5633007
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
DNA Double Strand Break Response R-HSA-5693606
Cell Cycle R-HSA-1640170
G2/M Checkpoints R-HSA-69481
DNA Repair R-HSA-73894
p53-Independent DNA Damage Response R-HSA-69610
DNA Double-Strand Break Repair R-HSA-5693532
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Expression and Degradation R-HSA-6806003
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of TP53 Activity through Methylation R-HSA-6804760
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Transcriptional Regulation by TP53 R-HSA-3700989
DNA Repair R-HSA-73894
Gene expression (Transcription) R-HSA-74160
p53-Independent DNA Damage Response R-HSA-69610
DNA Double Strand Break Response R-HSA-5693606
Generic Transcription Pathway R-HSA-212436
Stabilization of p53 R-HSA-69541
Regulation of TP53 Degradation R-HSA-6804757
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of TP53 Expression and Degradation R-HSA-6806003
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle R-HSA-1640170
DNA Double-Strand Break Repair R-HSA-5693532
G2/M DNA damage checkpoint R-HSA-69473
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G2/M Checkpoints R-HSA-69481
Regulation of TP53 Activity through Methylation R-HSA-6804760
p53-Dependent G1 DNA Damage Response R-HSA-69563
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cell Cycle Checkpoints R-HSA-69620
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity R-HSA-5633007

Expression Atlas ENSG00000183765
LRG display in Ensembl gene LRG_302
NCBI gene (formerly Entrezgene) 11200
GeneCards 16627
HGNC Symbol HGNC:16627
MIM gene 604373
MIM morbid 609265
UniProtKB Gene Name O96017
WikiGene 11200
Gene: FLT4
Ensembl ID : ENSG00000037280
Description: fms related receptor tyrosine kinase 4
Gene Synonyms: PCL,VEGFR-3,VEGFR3
46 APIs:
198 Possible Orthologues:

Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by NOTCH4 R-HSA-9013694
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH R-HSA-157118
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by VEGF R-HSA-194138
Signaling by NOTCH R-HSA-157118
Signaling by VEGF R-HSA-194138
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signal Transduction R-HSA-162582
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by NOTCH4 R-HSA-9013694
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by VEGF R-HSA-194138
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
Signaling by VEGF R-HSA-194138
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH R-HSA-157118
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by NOTCH4 R-HSA-9013694
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH R-HSA-157118
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by VEGF R-HSA-194138
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by VEGF R-HSA-194138
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694

Expression Atlas ENSG00000037280
NCBI gene (formerly Entrezgene) 2324
GeneCards 3767
HGNC Symbol HGNC:3767
MIM gene 136352
MIM morbid 618780
UniProtKB Gene Name P35916
WikiGene 2324
Gene: ROCK2
Ensembl ID : ENSG00000134318
Description: Rho associated coiled-coil containing protein kinase 2
Gene Synonyms:
11 APIs:
298 Possible Orthologues:

Axon guidance R-HSA-422475
Signaling by Rho GTPases R-HSA-194315
G alpha (12/13) signalling events R-HSA-416482
RHOH GTPase cycle R-HSA-9013407
EPH-Ephrin signaling R-HSA-2682334
Infectious disease R-HSA-5663205
RHOB GTPase cycle R-HSA-9013026
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
RHOC GTPase cycle R-HSA-9013106
RHOA GTPase cycle R-HSA-8980692
Potential therapeutics for SARS R-HSA-9679191
RHOBTB GTPase Cycle R-HSA-9706574
RHO GTPase cycle R-HSA-9012999
RHOBTB1 GTPase cycle R-HSA-9013422
EPHB-mediated forward signaling R-HSA-3928662
Sema4D in semaphorin signaling R-HSA-400685
Disease R-HSA-1643685
Signaling by VEGF R-HSA-194138
EPHA-mediated growth cone collapse R-HSA-3928663
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Semaphorin interactions R-HSA-373755
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
RHO GTPase Effectors R-HSA-195258
SARS-CoV Infections R-HSA-9679506
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPases Activate ROCKs R-HSA-5627117
GPCR downstream signalling R-HSA-388396
RHOH GTPase cycle R-HSA-9013407
Disease R-HSA-1643685
RHOBTB GTPase Cycle R-HSA-9706574
RHO GTPase Effectors R-HSA-195258
Signaling by Rho GTPases R-HSA-194315
EPH-Ephrin signaling R-HSA-2682334
Signaling by VEGF R-HSA-194138
G alpha (12/13) signalling events R-HSA-416482
Sema4D in semaphorin signaling R-HSA-400685
Infectious disease R-HSA-5663205
Semaphorin interactions R-HSA-373755
VEGFA-VEGFR2 Pathway R-HSA-4420097
EPHB-mediated forward signaling R-HSA-3928662
EPHA-mediated growth cone collapse R-HSA-3928663
SARS-CoV Infections R-HSA-9679506
Nervous system development R-HSA-9675108
RHOA GTPase cycle R-HSA-8980692
RHOBTB1 GTPase cycle R-HSA-9013422
Signal Transduction R-HSA-162582
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Potential therapeutics for SARS R-HSA-9679191
GPCR downstream signalling R-HSA-388396
RHOC GTPase cycle R-HSA-9013106
Signaling by GPCR R-HSA-372790
RHO GTPase cycle R-HSA-9012999
RHOB GTPase cycle R-HSA-9013026
RHO GTPases Activate ROCKs R-HSA-5627117
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPHA-mediated growth cone collapse R-HSA-3928663
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Rho GTPases R-HSA-194315
RHOC GTPase cycle R-HSA-9013106
Nervous system development R-HSA-9675108
EPH-Ephrin signaling R-HSA-2682334
RHO GTPases Activate ROCKs R-HSA-5627117
RHOA GTPase cycle R-HSA-8980692
Developmental Biology R-HSA-1266738
Sema4D in semaphorin signaling R-HSA-400685
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPHB-mediated forward signaling R-HSA-3928662
RHOH GTPase cycle R-HSA-9013407
RHO GTPase cycle R-HSA-9012999
VEGFA-VEGFR2 Pathway R-HSA-4420097
Axon guidance R-HSA-422475
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Potential therapeutics for SARS R-HSA-9679191
G alpha (12/13) signalling events R-HSA-416482
SARS-CoV Infections R-HSA-9679506
Semaphorin interactions R-HSA-373755
RHOBTB GTPase Cycle R-HSA-9706574
Signaling by VEGF R-HSA-194138
RHOBTB1 GTPase cycle R-HSA-9013422
RHO GTPase Effectors R-HSA-195258
Infectious disease R-HSA-5663205
RHOB GTPase cycle R-HSA-9013026
RHOB GTPase cycle R-HSA-9013026
Signaling by VEGF R-HSA-194138
Sema4D in semaphorin signaling R-HSA-400685
RHO GTPase Effectors R-HSA-195258
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
RHOH GTPase cycle R-HSA-9013407
RHOBTB1 GTPase cycle R-HSA-9013422
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
G alpha (12/13) signalling events R-HSA-416482
RHOBTB GTPase Cycle R-HSA-9706574
Developmental Biology R-HSA-1266738
RHO GTPase cycle R-HSA-9012999
GPCR downstream signalling R-HSA-388396
RHOC GTPase cycle R-HSA-9013106
Signaling by GPCR R-HSA-372790
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPHB-mediated forward signaling R-HSA-3928662
Potential therapeutics for SARS R-HSA-9679191
Infectious disease R-HSA-5663205
EPH-Ephrin signaling R-HSA-2682334
Signaling by Rho GTPases R-HSA-194315
EPHA-mediated growth cone collapse R-HSA-3928663
Semaphorin interactions R-HSA-373755
Nervous system development R-HSA-9675108
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Disease R-HSA-1643685
Axon guidance R-HSA-422475
RHO GTPases Activate ROCKs R-HSA-5627117
RHOA GTPase cycle R-HSA-8980692
SARS-CoV Infections R-HSA-9679506
RHO GTPase Effectors R-HSA-195258
RHOC GTPase cycle R-HSA-9013106
Nervous system development R-HSA-9675108
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Axon guidance R-HSA-422475
RHO GTPase cycle R-HSA-9012999
Signaling by Rho GTPases R-HSA-194315
RHOH GTPase cycle R-HSA-9013407
EPHB-mediated forward signaling R-HSA-3928662
Disease R-HSA-1643685
EPH-Ephrin signaling R-HSA-2682334
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Infectious disease R-HSA-5663205
G alpha (12/13) signalling events R-HSA-416482
SARS-CoV Infections R-HSA-9679506
RHOB GTPase cycle R-HSA-9013026
Developmental Biology R-HSA-1266738
Potential therapeutics for SARS R-HSA-9679191
Signaling by GPCR R-HSA-372790
Sema4D in semaphorin signaling R-HSA-400685
Semaphorin interactions R-HSA-373755
RHOBTB1 GTPase cycle R-HSA-9013422
GPCR downstream signalling R-HSA-388396
RHOA GTPase cycle R-HSA-8980692
RHOBTB GTPase Cycle R-HSA-9706574
RHO GTPases Activate ROCKs R-HSA-5627117
VEGFA-VEGFR2 Pathway R-HSA-4420097
EPHA-mediated growth cone collapse R-HSA-3928663
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Semaphorin interactions R-HSA-373755
Developmental Biology R-HSA-1266738
Signaling by VEGF R-HSA-194138
RHO GTPase cycle R-HSA-9012999
EPHA-mediated growth cone collapse R-HSA-3928663
RHOB GTPase cycle R-HSA-9013026
G alpha (12/13) signalling events R-HSA-416482
RHOA GTPase cycle R-HSA-8980692
RHOBTB1 GTPase cycle R-HSA-9013422
Infectious disease R-HSA-5663205
Axon guidance R-HSA-422475
Sema4D in semaphorin signaling R-HSA-400685
SARS-CoV Infections R-HSA-9679506
EPHB-mediated forward signaling R-HSA-3928662
Disease R-HSA-1643685
Potential therapeutics for SARS R-HSA-9679191
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPH-Ephrin signaling R-HSA-2682334
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases R-HSA-194315
RHOC GTPase cycle R-HSA-9013106
RHO GTPases Activate ROCKs R-HSA-5627117
RHOBTB GTPase Cycle R-HSA-9706574
GPCR downstream signalling R-HSA-388396
VEGFA-VEGFR2 Pathway R-HSA-4420097
RHO GTPase Effectors R-HSA-195258
RHOH GTPase cycle R-HSA-9013407
Signaling by GPCR R-HSA-372790
Nervous system development R-HSA-9675108
Signaling by VEGF R-HSA-194138
RHOH GTPase cycle R-HSA-9013407
RHOBTB GTPase Cycle R-HSA-9706574
RHOA GTPase cycle R-HSA-8980692
RHOC GTPase cycle R-HSA-9013106
Semaphorin interactions R-HSA-373755
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
EPHB-mediated forward signaling R-HSA-3928662
Developmental Biology R-HSA-1266738
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
RHOB GTPase cycle R-HSA-9013026
Nervous system development R-HSA-9675108
GPCR downstream signalling R-HSA-388396
SARS-CoV Infections R-HSA-9679506
RHO GTPase Effectors R-HSA-195258
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
G alpha (12/13) signalling events R-HSA-416482
Sema4D in semaphorin signaling R-HSA-400685
Potential therapeutics for SARS R-HSA-9679191
RHO GTPase cycle R-HSA-9012999
Axon guidance R-HSA-422475
EPH-Ephrin signaling R-HSA-2682334
Infectious disease R-HSA-5663205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHOBTB1 GTPase cycle R-HSA-9013422
RHO GTPases Activate ROCKs R-HSA-5627117
Disease R-HSA-1643685
EPHA-mediated growth cone collapse R-HSA-3928663
RHOB GTPase cycle R-HSA-9013026
Signal Transduction R-HSA-162582
RHOBTB1 GTPase cycle R-HSA-9013422
RHOH GTPase cycle R-HSA-9013407
Semaphorin interactions R-HSA-373755
Signaling by GPCR R-HSA-372790
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHO GTPase Effectors R-HSA-195258
Signaling by VEGF R-HSA-194138
EPH-Ephrin signaling R-HSA-2682334
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Signaling by Rho GTPases R-HSA-194315
RHOBTB GTPase Cycle R-HSA-9706574
Developmental Biology R-HSA-1266738
GPCR downstream signalling R-HSA-388396
Sema4D in semaphorin signaling R-HSA-400685
VEGFA-VEGFR2 Pathway R-HSA-4420097
RHOA GTPase cycle R-HSA-8980692
SARS-CoV Infections R-HSA-9679506
RHOC GTPase cycle R-HSA-9013106
EPHB-mediated forward signaling R-HSA-3928662
RHO GTPases Activate ROCKs R-HSA-5627117
Potential therapeutics for SARS R-HSA-9679191
Disease R-HSA-1643685
G alpha (12/13) signalling events R-HSA-416482
Infectious disease R-HSA-5663205
RHO GTPase cycle R-HSA-9012999
Axon guidance R-HSA-422475
EPHA-mediated growth cone collapse R-HSA-3928663
Nervous system development R-HSA-9675108
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Sema4D in semaphorin signaling R-HSA-400685
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases R-HSA-194315
RHO GTPases Activate ROCKs R-HSA-5627117
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Signaling by GPCR R-HSA-372790
Disease R-HSA-1643685
Potential therapeutics for SARS R-HSA-9679191
RHOBTB GTPase Cycle R-HSA-9706574
RHOB GTPase cycle R-HSA-9013026
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase cycle R-HSA-9012999
G alpha (12/13) signalling events R-HSA-416482
RHOBTB1 GTPase cycle R-HSA-9013422
Infectious disease R-HSA-5663205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFA-VEGFR2 Pathway R-HSA-4420097
RHOC GTPase cycle R-HSA-9013106
RHOA GTPase cycle R-HSA-8980692
Nervous system development R-HSA-9675108
EPHA-mediated growth cone collapse R-HSA-3928663
Semaphorin interactions R-HSA-373755
RHO GTPase Effectors R-HSA-195258
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
RHOH GTPase cycle R-HSA-9013407
Axon guidance R-HSA-422475
EPHB-mediated forward signaling R-HSA-3928662
SARS-CoV Infections R-HSA-9679506
GPCR downstream signalling R-HSA-388396
EPH-Ephrin signaling R-HSA-2682334
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
EPHA-mediated growth cone collapse R-HSA-3928663
RHO GTPases Activate ROCKs R-HSA-5627117
Axon guidance R-HSA-422475
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
EPHB-mediated forward signaling R-HSA-3928662
RHO GTPase cycle R-HSA-9012999
RHOA GTPase cycle R-HSA-8980692
GPCR downstream signalling R-HSA-388396
Nervous system development R-HSA-9675108
VEGFA-VEGFR2 Pathway R-HSA-4420097
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
RHOBTB1 GTPase cycle R-HSA-9013422
EPH-Ephrin signaling R-HSA-2682334
RHO GTPase Effectors R-HSA-195258
Signaling by GPCR R-HSA-372790
RHOB GTPase cycle R-HSA-9013026
Potential therapeutics for SARS R-HSA-9679191
RHOBTB GTPase Cycle R-HSA-9706574
RHOH GTPase cycle R-HSA-9013407
SARS-CoV Infections R-HSA-9679506
Semaphorin interactions R-HSA-373755
RHOC GTPase cycle R-HSA-9013106
Sema4D in semaphorin signaling R-HSA-400685
Infectious disease R-HSA-5663205
G alpha (12/13) signalling events R-HSA-416482
RHO GTPase Effectors R-HSA-195258
SARS-CoV Infections R-HSA-9679506
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHOB GTPase cycle R-HSA-9013026
Signaling by VEGF R-HSA-194138
RHOC GTPase cycle R-HSA-9013106
RHOBTB GTPase Cycle R-HSA-9706574
EPHB-mediated forward signaling R-HSA-3928662
RHOH GTPase cycle R-HSA-9013407
Nervous system development R-HSA-9675108
RHOBTB1 GTPase cycle R-HSA-9013422
RHOA GTPase cycle R-HSA-8980692
G alpha (12/13) signalling events R-HSA-416482
GPCR downstream signalling R-HSA-388396
Signaling by Rho GTPases R-HSA-194315
VEGFA-VEGFR2 Pathway R-HSA-4420097
Axon guidance R-HSA-422475
Potential therapeutics for SARS R-HSA-9679191
RHO GTPases Activate ROCKs R-HSA-5627117
EPHA-mediated growth cone collapse R-HSA-3928663
Signaling by GPCR R-HSA-372790
Sema4D in semaphorin signaling R-HSA-400685
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase cycle R-HSA-9012999
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPH-Ephrin signaling R-HSA-2682334
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Semaphorin interactions R-HSA-373755

Expression Atlas ENSG00000134318
NCBI gene (formerly Entrezgene) 9475
GeneCards 10252
HGNC Symbol HGNC:10252
MIM gene 604002
UniProtKB Gene Name O75116
WikiGene 9475
Gene: FGFR1
Ensembl ID : ENSG00000077782
Description: fibroblast growth factor receptor 1
Gene Synonyms: BFGFR,CD331,CEK,FLG,FLT2,H2,H3,H4,H5,KAL2,N-SAM
26 APIs:
293 Possible Orthologues:

MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by activated point mutants of FGFR1 R-HSA-1839122
MAPK family signaling cascades R-HSA-5683057
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR1 in disease R-HSA-5655302
Downstream signaling of activated FGFR1 R-HSA-5654687
RAF/MAP kinase cascade R-HSA-5673001
Gastrulation R-HSA-9758941
Signal Transduction R-HSA-162582
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
FGFR1 ligand binding and activation R-HSA-190242
Developmental Biology R-HSA-1266738
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K Cascade R-HSA-109704
Signaling by FGFR in disease R-HSA-1226099
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Negative regulation of the PI3K/AKT network R-HSA-199418
IGF1R signaling cascade R-HSA-2428924
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by FGFR1 R-HSA-5654736
L1CAM interactions R-HSA-373760
Signaling by FGFR R-HSA-190236
Formation of paraxial mesoderm R-HSA-9793380
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FRS-mediated FGFR1 signaling R-HSA-5654693
Axon guidance R-HSA-422475
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI-3K cascade:FGFR1 R-HSA-5654689
FGFR1b ligand binding and activation R-HSA-190370
Disease R-HSA-1643685
FGFR1c ligand binding and activation R-HSA-190373
Signal transduction by L1 R-HSA-445144
IRS-mediated signalling R-HSA-112399
Signaling by FGFR1 amplification mutants R-HSA-1839120
Signaling by Insulin receptor R-HSA-74752
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Negative regulation of FGFR1 signaling R-HSA-5654726
PI3K/AKT Signaling in Cancer R-HSA-2219528
FGFR1 mutant receptor activation R-HSA-1839124
Nervous system development R-HSA-9675108
PIP3 activates AKT signaling R-HSA-1257604
SHC-mediated cascade:FGFR1 R-HSA-5654688
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IGF1R signaling cascade R-HSA-2428924
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
PI3K/AKT Signaling in Cancer R-HSA-2219528
FRS-mediated FGFR1 signaling R-HSA-5654693
Signaling by FGFR1 in disease R-HSA-5655302
NCAM signaling for neurite out-growth R-HSA-375165
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR1 R-HSA-5654736
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR R-HSA-190236
L1CAM interactions R-HSA-373760
Signal Transduction R-HSA-162582
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Negative regulation of FGFR1 signaling R-HSA-5654726
FGFR1 mutant receptor activation R-HSA-1839124
Axon guidance R-HSA-422475
MAPK1/MAPK3 signaling R-HSA-5684996
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
IRS-mediated signalling R-HSA-112399
Signaling by FGFR in disease R-HSA-1226099
FGFR1c and Klotho ligand binding and activation R-HSA-190374
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Insulin receptor R-HSA-74752
Signal transduction by L1 R-HSA-445144
PI-3K cascade:FGFR1 R-HSA-5654689
PI3K Cascade R-HSA-109704
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
SHC-mediated cascade:FGFR1 R-HSA-5654688
MAPK family signaling cascades R-HSA-5683057
FGFR1b ligand binding and activation R-HSA-190370
FGFR1 ligand binding and activation R-HSA-190242
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Developmental Biology R-HSA-1266738
Signaling by FGFR1 amplification mutants R-HSA-1839120
Gastrulation R-HSA-9758941
FGFR1c ligand binding and activation R-HSA-190373
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by activated point mutants of FGFR1 R-HSA-1839122
Formation of paraxial mesoderm R-HSA-9793380
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
Signaling by FGFR1 amplification mutants R-HSA-1839120
Formation of paraxial mesoderm R-HSA-9793380
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Insulin receptor R-HSA-74752
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
RAF/MAP kinase cascade R-HSA-5673001
Gastrulation R-HSA-9758941
PI-3K cascade:FGFR1 R-HSA-5654689
Downstream signaling of activated FGFR1 R-HSA-5654687
SHC-mediated cascade:FGFR1 R-HSA-5654688
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by activated point mutants of FGFR1 R-HSA-1839122
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI3K Cascade R-HSA-109704
PIP3 activates AKT signaling R-HSA-1257604
FGFR1c ligand binding and activation R-HSA-190373
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
L1CAM interactions R-HSA-373760
MAPK1/MAPK3 signaling R-HSA-5684996
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by FGFR1 R-HSA-5654736
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Insulin receptor signalling cascade R-HSA-74751
FGFR1 ligand binding and activation R-HSA-190242
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR in disease R-HSA-1226099
IRS-related events triggered by IGF1R R-HSA-2428928
Signal transduction by L1 R-HSA-445144
Axon guidance R-HSA-422475
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Intracellular signaling by second messengers R-HSA-9006925
IRS-mediated signalling R-HSA-112399
Nervous system development R-HSA-9675108
IGF1R signaling cascade R-HSA-2428924
FRS-mediated FGFR1 signaling R-HSA-5654693
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Signaling by FGFR R-HSA-190236
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FGFR1b ligand binding and activation R-HSA-190370
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR R-HSA-190236
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
FRS-mediated FGFR1 signaling R-HSA-5654693
Downstream signaling of activated FGFR1 R-HSA-5654687
IRS-mediated signalling R-HSA-112399
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Signaling by Insulin receptor R-HSA-74752
PI3K Cascade R-HSA-109704
Nervous system development R-HSA-9675108
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Signal transduction by L1 R-HSA-445144
Gastrulation R-HSA-9758941
Signal Transduction R-HSA-162582
FGFR1b ligand binding and activation R-HSA-190370
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of FGFR1 signaling R-HSA-5654726
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
Intracellular signaling by second messengers R-HSA-9006925
Formation of paraxial mesoderm R-HSA-9793380
L1CAM interactions R-HSA-373760
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IGF1R signaling cascade R-HSA-2428924
Signaling by activated point mutants of FGFR1 R-HSA-1839122
IRS-related events triggered by IGF1R R-HSA-2428928
Axon guidance R-HSA-422475
Signaling by FGFR1 amplification mutants R-HSA-1839120
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by FGFR1 R-HSA-5654736
Insulin receptor signalling cascade R-HSA-74751
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Signaling by FGFR in disease R-HSA-1226099
FGFR1c ligand binding and activation R-HSA-190373
NCAM signaling for neurite out-growth R-HSA-375165
MAPK1/MAPK3 signaling R-HSA-5684996
FGFR1 ligand binding and activation R-HSA-190242
Negative regulation of the PI3K/AKT network R-HSA-199418
Developmental Biology R-HSA-1266738
MAPK family signaling cascades R-HSA-5683057
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
SHC-mediated cascade:FGFR1 R-HSA-5654688
FGFR1 mutant receptor activation R-HSA-1839124
Negative regulation of the PI3K/AKT network R-HSA-199418
Nervous system development R-HSA-9675108
FGFR1b ligand binding and activation R-HSA-190370
L1CAM interactions R-HSA-373760
Formation of paraxial mesoderm R-HSA-9793380
Signaling by activated point mutants of FGFR1 R-HSA-1839122
Signaling by FGFR1 R-HSA-5654736
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
IGF1R signaling cascade R-HSA-2428924
Intracellular signaling by second messengers R-HSA-9006925
SHC-mediated cascade:FGFR1 R-HSA-5654688
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FGFR1c ligand binding and activation R-HSA-190373
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signal transduction by L1 R-HSA-445144
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
IRS-mediated signalling R-HSA-112399
Signaling by FGFR1 in disease R-HSA-5655302
Negative regulation of FGFR1 signaling R-HSA-5654726
Signal Transduction R-HSA-162582
Gastrulation R-HSA-9758941
PI3K Cascade R-HSA-109704
Signaling by FGFR1 amplification mutants R-HSA-1839120
Developmental Biology R-HSA-1266738
Signaling by FGFR R-HSA-190236
IRS-related events triggered by IGF1R R-HSA-2428928
FRS-mediated FGFR1 signaling R-HSA-5654693
Disease R-HSA-1643685
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Insulin receptor R-HSA-74752
FGFR1 ligand binding and activation R-HSA-190242
MAPK family signaling cascades R-HSA-5683057
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Axon guidance R-HSA-422475
PI3K/AKT Signaling in Cancer R-HSA-2219528
Insulin receptor signalling cascade R-HSA-74751
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI-3K cascade:FGFR1 R-HSA-5654689
NCAM signaling for neurite out-growth R-HSA-375165
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Signaling by FGFR in disease R-HSA-1226099
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FGFR1 mutant receptor activation R-HSA-1839124
NCAM signaling for neurite out-growth R-HSA-375165
PIP3 activates AKT signaling R-HSA-1257604
Formation of paraxial mesoderm R-HSA-9793380
MAPK1/MAPK3 signaling R-HSA-5684996
Axon guidance R-HSA-422475
FGFR1c ligand binding and activation R-HSA-190373
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR R-HSA-190236
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Disease R-HSA-1643685
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR in disease R-HSA-1226099
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Insulin receptor signalling cascade R-HSA-74751
FGFR1 ligand binding and activation R-HSA-190242
Signal transduction by L1 R-HSA-445144
PI3K Cascade R-HSA-109704
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
RAF/MAP kinase cascade R-HSA-5673001
FGFR1b ligand binding and activation R-HSA-190370
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR1 amplification mutants R-HSA-1839120
Signaling by activated point mutants of FGFR1 R-HSA-1839122
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Gastrulation R-HSA-9758941
Nervous system development R-HSA-9675108
SHC-mediated cascade:FGFR1 R-HSA-5654688
Developmental Biology R-HSA-1266738
Signaling by FGFR1 R-HSA-5654736
Negative regulation of FGFR1 signaling R-HSA-5654726
FRS-mediated FGFR1 signaling R-HSA-5654693
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
L1CAM interactions R-HSA-373760
Downstream signaling of activated FGFR1 R-HSA-5654687
IRS-related events triggered by IGF1R R-HSA-2428928
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR1 in disease R-HSA-5655302
IRS-mediated signalling R-HSA-112399
PI-3K cascade:FGFR1 R-HSA-5654689
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
FGFR1 mutant receptor activation R-HSA-1839124
Formation of paraxial mesoderm R-HSA-9793380
Signaling by FGFR1 R-HSA-5654736
MAPK family signaling cascades R-HSA-5683057
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by FGFR1 in disease R-HSA-5655302
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IGF1R signaling cascade R-HSA-2428924
Disease R-HSA-1643685
Signaling by FGFR in disease R-HSA-1226099
Insulin receptor signalling cascade R-HSA-74751
FGFR1c and Klotho ligand binding and activation R-HSA-190374
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Insulin receptor R-HSA-74752
Signaling by activated point mutants of FGFR1 R-HSA-1839122
PIP3 activates AKT signaling R-HSA-1257604
FRS-mediated FGFR1 signaling R-HSA-5654693
Intracellular signaling by second messengers R-HSA-9006925
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
SHC-mediated cascade:FGFR1 R-HSA-5654688
Axon guidance R-HSA-422475
IRS-mediated signalling R-HSA-112399
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
FGFR1c ligand binding and activation R-HSA-190373
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
L1CAM interactions R-HSA-373760
Signal transduction by L1 R-HSA-445144
PI3K Cascade R-HSA-109704
PI3K/AKT Signaling in Cancer R-HSA-2219528
Downstream signaling of activated FGFR1 R-HSA-5654687
PI-3K cascade:FGFR1 R-HSA-5654689
FGFR1 ligand binding and activation R-HSA-190242
Signaling by FGFR1 amplification mutants R-HSA-1839120
Negative regulation of FGFR1 signaling R-HSA-5654726
Developmental Biology R-HSA-1266738
FGFR1b ligand binding and activation R-HSA-190370
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by FGFR R-HSA-190236
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Negative regulation of the PI3K/AKT network R-HSA-199418
Gastrulation R-HSA-9758941
IRS-related events triggered by IGF1R R-HSA-2428928
FGFR1c ligand binding and activation R-HSA-190373
Disease R-HSA-1643685
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
RAF/MAP kinase cascade R-HSA-5673001
IRS-related events triggered by IGF1R R-HSA-2428928
IRS-mediated signalling R-HSA-112399
SHC-mediated cascade:FGFR1 R-HSA-5654688
Nervous system development R-HSA-9675108
PIP3 activates AKT signaling R-HSA-1257604
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR in disease R-HSA-1226099
Negative regulation of FGFR1 signaling R-HSA-5654726
Developmental Biology R-HSA-1266738
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR1 in disease R-HSA-5655302
PI3K/AKT Signaling in Cancer R-HSA-2219528
FGFR1b ligand binding and activation R-HSA-190370
IGF1R signaling cascade R-HSA-2428924
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FGFR1 ligand binding and activation R-HSA-190242
Insulin receptor signalling cascade R-HSA-74751
Negative regulation of the PI3K/AKT network R-HSA-199418
NCAM signaling for neurite out-growth R-HSA-375165
PI-3K cascade:FGFR1 R-HSA-5654689
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Gastrulation R-HSA-9758941
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by activated point mutants of FGFR1 R-HSA-1839122
Signal transduction by L1 R-HSA-445144
L1CAM interactions R-HSA-373760
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
FRS-mediated FGFR1 signaling R-HSA-5654693
FGFR1 mutant receptor activation R-HSA-1839124
Formation of paraxial mesoderm R-HSA-9793380
Signaling by FGFR R-HSA-190236
FGFR1c and Klotho ligand binding and activation R-HSA-190374
PI3K Cascade R-HSA-109704
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by FGFR1 amplification mutants R-HSA-1839120
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR1 R-HSA-5654736
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signaling of activated FGFR1 R-HSA-5654687
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
FGFR1c ligand binding and activation R-HSA-190373
IGF1R signaling cascade R-HSA-2428924
Nervous system development R-HSA-9675108
FGFR1 ligand binding and activation R-HSA-190242
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR R-HSA-190236
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Insulin receptor signalling cascade R-HSA-74751
L1CAM interactions R-HSA-373760
Intracellular signaling by second messengers R-HSA-9006925
Signaling by activated point mutants of FGFR1 R-HSA-1839122
PIP3 activates AKT signaling R-HSA-1257604
Signaling by FGFR1 in disease R-HSA-5655302
Signal transduction by L1 R-HSA-445144
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
Signaling by FGFR1 R-HSA-5654736
IRS-mediated signalling R-HSA-112399
Signaling by FGFR in disease R-HSA-1226099
NCAM signaling for neurite out-growth R-HSA-375165
IRS-related events triggered by IGF1R R-HSA-2428928
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
Developmental Biology R-HSA-1266738
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by FGFR1 amplification mutants R-HSA-1839120
Axon guidance R-HSA-422475
FGFR1c and Klotho ligand binding and activation R-HSA-190374
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Insulin receptor R-HSA-74752
Formation of paraxial mesoderm R-HSA-9793380
SHC-mediated cascade:FGFR1 R-HSA-5654688
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K Cascade R-HSA-109704
FRS-mediated FGFR1 signaling R-HSA-5654693
MAPK family signaling cascades R-HSA-5683057
Gastrulation R-HSA-9758941
RAF/MAP kinase cascade R-HSA-5673001
FGFR1b ligand binding and activation R-HSA-190370
Developmental Biology R-HSA-1266738
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR R-HSA-190236
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FGFR1 mutant receptor activation R-HSA-1839124
Signal Transduction R-HSA-162582
IRS-related events triggered by IGF1R R-HSA-2428928
Formation of paraxial mesoderm R-HSA-9793380
PI3K Cascade R-HSA-109704
Disease R-HSA-1643685
L1CAM interactions R-HSA-373760
Signal transduction by L1 R-HSA-445144
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by FGFR1 in disease R-HSA-5655302
MAPK family signaling cascades R-HSA-5683057
IRS-mediated signalling R-HSA-112399
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by activated point mutants of FGFR1 R-HSA-1839122
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Signaling by FGFR1 R-HSA-5654736
Signaling by FGFR1 amplification mutants R-HSA-1839120
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Signaling by Insulin receptor R-HSA-74752
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF/MAP kinase cascade R-HSA-5673001
SHC-mediated cascade:FGFR1 R-HSA-5654688
Axon guidance R-HSA-422475
IGF1R signaling cascade R-HSA-2428924
MAPK1/MAPK3 signaling R-HSA-5684996
Nervous system development R-HSA-9675108
Downstream signaling of activated FGFR1 R-HSA-5654687
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Gastrulation R-HSA-9758941
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
NCAM signaling for neurite out-growth R-HSA-375165
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
Insulin receptor signalling cascade R-HSA-74751
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
FGFR1b ligand binding and activation R-HSA-190370
FGFR1 ligand binding and activation R-HSA-190242
FGFR1c ligand binding and activation R-HSA-190373
Signaling by FGFR in disease R-HSA-1226099
FRS-mediated FGFR1 signaling R-HSA-5654693

Expression Atlas ENSG00000077782
LRG display in Ensembl gene LRG_993
NCBI gene (formerly Entrezgene) 2260
GeneCards 3688
HGNC Symbol HGNC:3688
MIM gene 136350
MIM morbid 615465
UniProtKB Gene Name P11362
WikiGene 2260