Gene: PRKCG
Ensembl ID : ENSG00000126583
Description: protein kinase C gamma
Gene Synonyms: MGC57564,PKCC,PKCG,SCA14
5 APIs:
200 Possible Orthologues:

G alpha (i) signalling events R-HSA-418594
DAG and IP3 signaling R-HSA-1489509
Transmission across Chemical Synapses R-HSA-112315
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
PLC beta mediated events R-HSA-112043
G alpha (z) signalling events R-HSA-418597
Beta-catenin independent WNT signaling R-HSA-3858494
CaM pathway R-HSA-111997
Signaling by WNT R-HSA-195721
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Trafficking of AMPA receptors R-HSA-399719
Intracellular signaling by second messengers R-HSA-9006925
Neuronal System R-HSA-112316
Platelet activation, signaling and aggregation R-HSA-76002
Disinhibition of SNARE formation R-HSA-114516
PCP/CE pathway R-HSA-4086400
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Calmodulin induced events R-HSA-111933
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Opioid Signalling R-HSA-111885
Ca-dependent events R-HSA-111996
Signal Transduction R-HSA-162582
WNT5A-dependent internalization of FZD4 R-HSA-5099900
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
PLC beta mediated events R-HSA-112043
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Opioid Signalling R-HSA-111885
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
GPCR downstream signalling R-HSA-388396
PCP/CE pathway R-HSA-4086400
G-protein mediated events R-HSA-112040
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
G alpha (i) signalling events R-HSA-418594
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (z) signalling events R-HSA-418597
Signaling by WNT R-HSA-195721
Calmodulin induced events R-HSA-111933
Intracellular signaling by second messengers R-HSA-9006925
Ca-dependent events R-HSA-111996
Signal Transduction R-HSA-162582
Trafficking of AMPA receptors R-HSA-399719
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by GPCR R-HSA-372790
CaM pathway R-HSA-111997
Disinhibition of SNARE formation R-HSA-114516
DAG and IP3 signaling R-HSA-1489509
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
G alpha (i) signalling events R-HSA-418594
PCP/CE pathway R-HSA-4086400
PLC beta mediated events R-HSA-112043
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Signaling by WNT R-HSA-195721
Ca-dependent events R-HSA-111996
DAG and IP3 signaling R-HSA-1489509
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
Intracellular signaling by second messengers R-HSA-9006925
WNT5A-dependent internalization of FZD4 R-HSA-5099900
G alpha (z) signalling events R-HSA-418597
Opioid Signalling R-HSA-111885
Beta-catenin independent WNT signaling R-HSA-3858494
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Calmodulin induced events R-HSA-111933
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Disinhibition of SNARE formation R-HSA-114516
CaM pathway R-HSA-111997
Trafficking of AMPA receptors R-HSA-399719
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Neuronal System R-HSA-112316
Beta-catenin independent WNT signaling R-HSA-3858494
DAG and IP3 signaling R-HSA-1489509
Calmodulin induced events R-HSA-111933
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Intracellular signaling by second messengers R-HSA-9006925
Trafficking of AMPA receptors R-HSA-399719
Signal Transduction R-HSA-162582
Ca-dependent events R-HSA-111996
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by WNT R-HSA-195721
G-protein mediated events R-HSA-112040
Signaling by GPCR R-HSA-372790
PCP/CE pathway R-HSA-4086400
PLC beta mediated events R-HSA-112043
G alpha (i) signalling events R-HSA-418594
G alpha (z) signalling events R-HSA-418597
GPCR downstream signalling R-HSA-388396
Opioid Signalling R-HSA-111885
Transmission across Chemical Synapses R-HSA-112315
CaM pathway R-HSA-111997
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Disinhibition of SNARE formation R-HSA-114516
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
DAG and IP3 signaling R-HSA-1489509
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signaling by WNT R-HSA-195721
PLC beta mediated events R-HSA-112043
Intracellular signaling by second messengers R-HSA-9006925
G-protein mediated events R-HSA-112040
PCP/CE pathway R-HSA-4086400
Neuronal System R-HSA-112316
Signal Transduction R-HSA-162582
Ca-dependent events R-HSA-111996
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Calmodulin induced events R-HSA-111933
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Disinhibition of SNARE formation R-HSA-114516
G alpha (z) signalling events R-HSA-418597
CaM pathway R-HSA-111997
Transmission across Chemical Synapses R-HSA-112315
Signaling by GPCR R-HSA-372790
Beta-catenin independent WNT signaling R-HSA-3858494
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Platelet activation, signaling and aggregation R-HSA-76002
Trafficking of AMPA receptors R-HSA-399719
Opioid Signalling R-HSA-111885
Beta-catenin independent WNT signaling R-HSA-3858494
G alpha (i) signalling events R-HSA-418594
Hemostasis R-HSA-109582
WNT5A-dependent internalization of FZD4 R-HSA-5099900
G-protein mediated events R-HSA-112040
Trafficking of AMPA receptors R-HSA-399719
PCP/CE pathway R-HSA-4086400
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Calmodulin induced events R-HSA-111933
GPCR downstream signalling R-HSA-388396
Disinhibition of SNARE formation R-HSA-114516
DAG and IP3 signaling R-HSA-1489509
Transmission across Chemical Synapses R-HSA-112315
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neuronal System R-HSA-112316
Ca-dependent events R-HSA-111996
G alpha (z) signalling events R-HSA-418597
Opioid Signalling R-HSA-111885
PLC beta mediated events R-HSA-112043
Intracellular signaling by second messengers R-HSA-9006925
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Signaling by WNT R-HSA-195721
Platelet activation, signaling and aggregation R-HSA-76002
CaM pathway R-HSA-111997
Signaling by GPCR R-HSA-372790
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signal Transduction R-HSA-162582
Beta-catenin independent WNT signaling R-HSA-3858494
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
GPCR downstream signalling R-HSA-388396
DAG and IP3 signaling R-HSA-1489509
Trafficking of AMPA receptors R-HSA-399719
Ca-dependent events R-HSA-111996
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signaling by GPCR R-HSA-372790
CaM pathway R-HSA-111997
Signaling by WNT R-HSA-195721
Calmodulin induced events R-HSA-111933
PLC beta mediated events R-HSA-112043
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neuronal System R-HSA-112316
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
Platelet activation, signaling and aggregation R-HSA-76002
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Transmission across Chemical Synapses R-HSA-112315
Opioid Signalling R-HSA-111885
Disinhibition of SNARE formation R-HSA-114516
G alpha (z) signalling events R-HSA-418597
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Hemostasis R-HSA-109582
CaM pathway R-HSA-111997
Trafficking of AMPA receptors R-HSA-399719
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Transmission across Chemical Synapses R-HSA-112315
Signaling by WNT R-HSA-195721
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Disinhibition of SNARE formation R-HSA-114516
G alpha (z) signalling events R-HSA-418597
DAG and IP3 signaling R-HSA-1489509
Platelet activation, signaling and aggregation R-HSA-76002
Neuronal System R-HSA-112316
Calmodulin induced events R-HSA-111933
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Opioid Signalling R-HSA-111885
Ca-dependent events R-HSA-111996
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
PLC beta mediated events R-HSA-112043
G-protein mediated events R-HSA-112040
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
CaM pathway R-HSA-111997
PLC beta mediated events R-HSA-112043
Beta-catenin independent WNT signaling R-HSA-3858494
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Opioid Signalling R-HSA-111885
Intracellular signaling by second messengers R-HSA-9006925
Trafficking of AMPA receptors R-HSA-399719
G alpha (i) signalling events R-HSA-418594
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
G-protein mediated events R-HSA-112040
Disinhibition of SNARE formation R-HSA-114516
PCP/CE pathway R-HSA-4086400
Neuronal System R-HSA-112316
Hemostasis R-HSA-109582
GPCR downstream signalling R-HSA-388396
Transmission across Chemical Synapses R-HSA-112315
Signaling by GPCR R-HSA-372790
Ca-dependent events R-HSA-111996
G alpha (z) signalling events R-HSA-418597
DAG and IP3 signaling R-HSA-1489509
Signaling by WNT R-HSA-195721
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Calmodulin induced events R-HSA-111933
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Disinhibition of SNARE formation R-HSA-114516
Opioid Signalling R-HSA-111885
Signal Transduction R-HSA-162582
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Beta-catenin independent WNT signaling R-HSA-3858494
Intracellular signaling by second messengers R-HSA-9006925
Ca-dependent events R-HSA-111996
Calmodulin induced events R-HSA-111933
Signaling by GPCR R-HSA-372790
G-protein mediated events R-HSA-112040
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
DAG and IP3 signaling R-HSA-1489509
Neuronal System R-HSA-112316
G alpha (z) signalling events R-HSA-418597
PCP/CE pathway R-HSA-4086400
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Platelet activation, signaling and aggregation R-HSA-76002
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by WNT R-HSA-195721
CaM pathway R-HSA-111997
G alpha (i) signalling events R-HSA-418594
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
PLC beta mediated events R-HSA-112043
Trafficking of AMPA receptors R-HSA-399719
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Transmission across Chemical Synapses R-HSA-112315

Expression Atlas ENSG00000126583
LRG display in Ensembl gene LRG_669
NCBI gene (formerly Entrezgene) 5582
GeneCards 9402
HGNC Symbol HGNC:9402
MIM gene 176980
MIM morbid 605361
UniProtKB Gene Name P05129
WikiGene 5582
Gene: FGFR2
Ensembl ID : ENSG00000066468
Description: fibroblast growth factor receptor 2
Gene Synonyms: BEK,CD332,CEK3,CFD1,ECT1,JWS,K-SAM,KGFR,TK14,TK25
27 APIs:
218 Possible Orthologues:

Activated point mutants of FGFR2 R-HSA-2033519
PI3K Cascade R-HSA-109704
FGFR2b ligand binding and activation R-HSA-190377
FGFR2 alternative splicing R-HSA-6803529
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FGFR2c ligand binding and activation R-HSA-190375
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR in disease R-HSA-1226099
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Insulin receptor R-HSA-74752
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by FGFR R-HSA-190236
Signaling by FGFR2 IIIa TM R-HSA-8851708
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by FGFR2 R-HSA-5654738
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 amplification mutants R-HSA-2023837
FGFR2 ligand binding and activation R-HSA-190241
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
FGFR2 mutant receptor activation R-HSA-1839126
Insulin receptor signalling cascade R-HSA-74751
SHC-mediated cascade:FGFR2 R-HSA-5654699
PIP3 activates AKT signaling R-HSA-1257604
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by FGFR2 fusions R-HSA-8853333
IRS-mediated signalling R-HSA-112399
Negative regulation of the PI3K/AKT network R-HSA-199418
Negative regulation of FGFR2 signaling R-HSA-5654727
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Disease R-HSA-1643685
Signaling by FGFR2 fusions R-HSA-8853333
IRS-mediated signalling R-HSA-112399
Signaling by FGFR2 in disease R-HSA-5655253
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
FGFR2c ligand binding and activation R-HSA-190375
Insulin receptor signalling cascade R-HSA-74751
FGFR2 ligand binding and activation R-HSA-190241
FGFR2b ligand binding and activation R-HSA-190377
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Downstream signaling of activated FGFR2 R-HSA-5654696
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IGF1R signaling cascade R-HSA-2428924
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR R-HSA-190236
PI3K Cascade R-HSA-109704
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR in disease R-HSA-1226099
Negative regulation of FGFR2 signaling R-HSA-5654727
Activated point mutants of FGFR2 R-HSA-2033519
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 R-HSA-5654738
FGFR2 mutant receptor activation R-HSA-1839126
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by FGFR2 IIIa TM R-HSA-8851708
IRS-related events triggered by IGF1R R-HSA-2428928
PI-3K cascade:FGFR2 R-HSA-5654695
FGFR2 alternative splicing R-HSA-6803529
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Activated point mutants of FGFR2 R-HSA-2033519
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling of activated FGFR2 R-HSA-5654696
FGFR2 alternative splicing R-HSA-6803529
FGFR2c ligand binding and activation R-HSA-190375
Signal Transduction R-HSA-162582
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by FGFR2 IIIa TM R-HSA-8851708
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 amplification mutants R-HSA-2023837
FGFR2 ligand binding and activation R-HSA-190241
Negative regulation of the PI3K/AKT network R-HSA-199418
FGFR2 mutant receptor activation R-HSA-1839126
PI3K Cascade R-HSA-109704
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
IRS-mediated signalling R-HSA-112399
Signaling by FGFR in disease R-HSA-1226099
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR R-HSA-190236
IGF1R signaling cascade R-HSA-2428924
FGFR2b ligand binding and activation R-HSA-190377
Disease R-HSA-1643685
Signaling by Insulin receptor R-HSA-74752
PI3K/AKT Signaling in Cancer R-HSA-2219528
Insulin receptor signalling cascade R-HSA-74751
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR2 in disease R-HSA-5655253
RAF/MAP kinase cascade R-HSA-5673001
FRS-mediated FGFR2 signaling R-HSA-5654700
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 in disease R-HSA-5655253
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FGFR2 ligand binding and activation R-HSA-190241
MAPK1/MAPK3 signaling R-HSA-5684996
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR2 IIIa TM R-HSA-8851708
Disease R-HSA-1643685
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2c ligand binding and activation R-HSA-190375
Signaling by FGFR R-HSA-190236
Downstream signaling of activated FGFR2 R-HSA-5654696
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR in disease R-HSA-1226099
PI3K Cascade R-HSA-109704
IRS-mediated signalling R-HSA-112399
Insulin receptor signalling cascade R-HSA-74751
IGF1R signaling cascade R-HSA-2428924
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR2 R-HSA-5654738
PIP3 activates AKT signaling R-HSA-1257604
FRS-mediated FGFR2 signaling R-HSA-5654700
SHC-mediated cascade:FGFR2 R-HSA-5654699
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FGFR2b ligand binding and activation R-HSA-190377
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by Insulin receptor R-HSA-74752
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI-3K cascade:FGFR2 R-HSA-5654695
IRS-related events triggered by IGF1R R-HSA-2428928
MAPK family signaling cascades R-HSA-5683057
IRS-mediated signalling R-HSA-112399
PIP3 activates AKT signaling R-HSA-1257604
Signaling by FGFR2 IIIa TM R-HSA-8851708
FGFR2 ligand binding and activation R-HSA-190241
PI3K Cascade R-HSA-109704
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by FGFR2 in disease R-HSA-5655253
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2b ligand binding and activation R-HSA-190377
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR2 amplification mutants R-HSA-2023837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Signaling by FGFR in disease R-HSA-1226099
FGFR2c ligand binding and activation R-HSA-190375
RAF/MAP kinase cascade R-HSA-5673001
PI3K/AKT Signaling in Cancer R-HSA-2219528
SHC-mediated cascade:FGFR2 R-HSA-5654699
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
FRS-mediated FGFR2 signaling R-HSA-5654700
Disease R-HSA-1643685
IRS-related events triggered by IGF1R R-HSA-2428928
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
FGFR2 alternative splicing R-HSA-6803529
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR R-HSA-190236
IGF1R signaling cascade R-HSA-2428924
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 in disease R-HSA-5655253
FGFR2c ligand binding and activation R-HSA-190375
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
Negative regulation of the PI3K/AKT network R-HSA-199418
FGFR2 ligand binding and activation R-HSA-190241
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
MAPK1/MAPK3 signaling R-HSA-5684996
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 amplification mutants R-HSA-2023837
IRS-related events triggered by IGF1R R-HSA-2428928
Negative regulation of FGFR2 signaling R-HSA-5654727
RAF/MAP kinase cascade R-HSA-5673001
IRS-mediated signalling R-HSA-112399
IGF1R signaling cascade R-HSA-2428924
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by FGFR2 IIIa TM R-HSA-8851708
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR in disease R-HSA-1226099
PI3K Cascade R-HSA-109704
MAPK family signaling cascades R-HSA-5683057
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Disease R-HSA-1643685
Downstream signaling of activated FGFR2 R-HSA-5654696
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR R-HSA-190236
Intracellular signaling by second messengers R-HSA-9006925
FRS-mediated FGFR2 signaling R-HSA-5654700
FGFR2 mutant receptor activation R-HSA-1839126
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2b ligand binding and activation R-HSA-190377
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Insulin receptor signalling cascade R-HSA-74751
IGF1R signaling cascade R-HSA-2428924
PIP3 activates AKT signaling R-HSA-1257604
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K Cascade R-HSA-109704
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR R-HSA-190236
Signaling by FGFR2 amplification mutants R-HSA-2023837
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2 mutant receptor activation R-HSA-1839126
Signal Transduction R-HSA-162582
FRS-mediated FGFR2 signaling R-HSA-5654700
IRS-mediated signalling R-HSA-112399
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 IIIa TM R-HSA-8851708
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR in disease R-HSA-1226099
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Negative regulation of FGFR2 signaling R-HSA-5654727
PI3K/AKT Signaling in Cancer R-HSA-2219528
Disease R-HSA-1643685
FGFR2c ligand binding and activation R-HSA-190375
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FGFR2 ligand binding and activation R-HSA-190241
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 in disease R-HSA-5655253
IRS-related events triggered by IGF1R R-HSA-2428928
FGFR2 alternative splicing R-HSA-6803529
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling of activated FGFR2 R-HSA-5654696
Insulin receptor signalling cascade R-HSA-74751
FGFR2b ligand binding and activation R-HSA-190377
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IGF1R signaling cascade R-HSA-2428924
Activated point mutants of FGFR2 R-HSA-2033519
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 amplification mutants R-HSA-2023837
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
SHC-mediated cascade:FGFR2 R-HSA-5654699
PIP3 activates AKT signaling R-HSA-1257604
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by FGFR2 fusions R-HSA-8853333
Downstream signaling of activated FGFR2 R-HSA-5654696
FGFR2c ligand binding and activation R-HSA-190375
Negative regulation of FGFR2 signaling R-HSA-5654727
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR2 IIIa TM R-HSA-8851708
Disease R-HSA-1643685
FGFR2 ligand binding and activation R-HSA-190241
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR R-HSA-190236
PI-3K cascade:FGFR2 R-HSA-5654695
FGFR2b ligand binding and activation R-HSA-190377
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR2 in disease R-HSA-5655253
IRS-mediated signalling R-HSA-112399
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR in disease R-HSA-1226099
IRS-related events triggered by IGF1R R-HSA-2428928
PI3K Cascade R-HSA-109704
FGFR2 alternative splicing R-HSA-6803529
Signal Transduction R-HSA-162582
FGFR2 mutant receptor activation R-HSA-1839126
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 in disease R-HSA-5655253
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by FGFR2 amplification mutants R-HSA-2023837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR in disease R-HSA-1226099
Disease R-HSA-1643685
Negative regulation of FGFR2 signaling R-HSA-5654727
PIP3 activates AKT signaling R-HSA-1257604
FGFR2 mutant receptor activation R-HSA-1839126
Signaling by FGFR2 IIIa TM R-HSA-8851708
Signaling by FGFR R-HSA-190236
Signal Transduction R-HSA-162582
FGFR2b ligand binding and activation R-HSA-190377
IRS-mediated signalling R-HSA-112399
FGFR2c ligand binding and activation R-HSA-190375
IGF1R signaling cascade R-HSA-2428924
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
IRS-related events triggered by IGF1R R-HSA-2428928
PI3K Cascade R-HSA-109704
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Insulin receptor R-HSA-74752
PI-3K cascade:FGFR2 R-HSA-5654695
Negative regulation of the PI3K/AKT network R-HSA-199418
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2 ligand binding and activation R-HSA-190241
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
SHC-mediated cascade:FGFR2 R-HSA-5654699
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 IIIa TM R-HSA-8851708
SHC-mediated cascade:FGFR2 R-HSA-5654699
FGFR2b ligand binding and activation R-HSA-190377
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 in disease R-HSA-5655253
IRS-related events triggered by IGF1R R-HSA-2428928
MAPK family signaling cascades R-HSA-5683057
FGFR2c ligand binding and activation R-HSA-190375
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR2 R-HSA-5654738
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR2 fusions R-HSA-8853333
Negative regulation of FGFR2 signaling R-HSA-5654727
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR R-HSA-190236
Activated point mutants of FGFR2 R-HSA-2033519
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Disease R-HSA-1643685
PI-3K cascade:FGFR2 R-HSA-5654695
MAPK1/MAPK3 signaling R-HSA-5684996
FRS-mediated FGFR2 signaling R-HSA-5654700
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
PI3K Cascade R-HSA-109704
Signaling by FGFR in disease R-HSA-1226099
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2 ligand binding and activation R-HSA-190241
FGFR2 alternative splicing R-HSA-6803529
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS-mediated signalling R-HSA-112399

Expression Atlas ENSG00000066468
LRG display in Ensembl gene LRG_994
NCBI gene (formerly Entrezgene) 2263
GeneCards 3689
HGNC Symbol HGNC:3689
MIM gene 176943
MIM morbid 614592
UniProtKB Gene Name S4R3B2
WikiGene 2263
Gene: BTK
Ensembl ID : ENSG00000010671
Description: Bruton tyrosine kinase
Gene Synonyms: AGMX1,ATK,IMD1,PSCTK1,XLA
19 APIs:
206 Possible Orthologues:

Antigen processing-Cross presentation R-HSA-1236975
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Leishmania phagocytosis R-HSA-9664417
DAP12 signaling R-HSA-2424491
G beta:gamma signalling through BTK R-HSA-8964315
Diseases of Immune System R-HSA-5260271
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
MyD88 deficiency (TLR2/4) R-HSA-5602498
DAP12 interactions R-HSA-2172127
Leishmania infection R-HSA-9658195
Signal Transduction R-HSA-162582
IRAK4 deficiency (TLR2/4) R-HSA-5603041
G-protein beta:gamma signalling R-HSA-397795
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Rho GTPases R-HSA-194315
Parasite infection R-HSA-9664407
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
SARS-CoV Infections R-HSA-9679506
Potential therapeutics for SARS R-HSA-9679191
G alpha (q) signalling events R-HSA-416476
Toll-like Receptor Cascades R-HSA-168898
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by GPCR R-HSA-372790
FCERI mediated Ca+2 mobilization R-HSA-2871809
FCGR3A-mediated phagocytosis R-HSA-9664422
Diseases associated with the TLR signaling cascade R-HSA-5602358
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
GPCR downstream signalling R-HSA-388396
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Class I MHC mediated antigen processing & presentation R-HSA-983169
G alpha (12/13) signalling events R-HSA-416482
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
Adaptive Immune System R-HSA-1280218
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RHO GTPase Effectors R-HSA-195258
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ER-Phagosome pathway R-HSA-1236974
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll-like Receptor Cascades R-HSA-168898
Parasite infection R-HSA-9664407
G alpha (q) signalling events R-HSA-416476
Immune System R-HSA-168256
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Leishmania phagocytosis R-HSA-9664417
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
SARS-CoV Infections R-HSA-9679506
Diseases associated with the TLR signaling cascade R-HSA-5602358
FCERI mediated Ca+2 mobilization R-HSA-2871809
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Adaptive Immune System R-HSA-1280218
Signaling by Rho GTPases R-HSA-194315
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
G beta:gamma signalling through BTK R-HSA-8964315
Innate Immune System R-HSA-168249
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Antigen processing-Cross presentation R-HSA-1236975
G-protein beta:gamma signalling R-HSA-397795
IRAK4 deficiency (TLR2/4) R-HSA-5603041
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RHO GTPase Effectors R-HSA-195258
Infectious disease R-HSA-5663205
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
ER-Phagosome pathway R-HSA-1236974
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
DAP12 signaling R-HSA-2424491
MyD88 deficiency (TLR2/4) R-HSA-5602498
Leishmania infection R-HSA-9658195
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
DAP12 interactions R-HSA-2172127
Potential therapeutics for SARS R-HSA-9679191
Class I MHC mediated antigen processing & presentation R-HSA-983169
G alpha (12/13) signalling events R-HSA-416482
Diseases of Immune System R-HSA-5260271
Innate Immune System R-HSA-168249
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
IRAK4 deficiency (TLR2/4) R-HSA-5603041
DAP12 signaling R-HSA-2424491
GPCR downstream signalling R-HSA-388396
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Diseases of Immune System R-HSA-5260271
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Diseases associated with the TLR signaling cascade R-HSA-5602358
Signaling by Rho GTPases R-HSA-194315
MyD88 deficiency (TLR2/4) R-HSA-5602498
FCERI mediated Ca+2 mobilization R-HSA-2871809
Class I MHC mediated antigen processing & presentation R-HSA-983169
ER-Phagosome pathway R-HSA-1236974
SARS-CoV Infections R-HSA-9679506
Infectious disease R-HSA-5663205
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DAP12 interactions R-HSA-2172127
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Leishmania phagocytosis R-HSA-9664417
Adaptive Immune System R-HSA-1280218
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G beta:gamma signalling through BTK R-HSA-8964315
Antigen processing-Cross presentation R-HSA-1236975
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Leishmania infection R-HSA-9658195
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
G alpha (12/13) signalling events R-HSA-416482
Toll-like Receptor Cascades R-HSA-168898
Disease R-HSA-1643685
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Immune System R-HSA-168256
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
RHO GTPase Effectors R-HSA-195258
Potential therapeutics for SARS R-HSA-9679191
Parasite infection R-HSA-9664407
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Signal Transduction R-HSA-162582
G-protein beta:gamma signalling R-HSA-397795
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Disease R-HSA-1643685
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Innate Immune System R-HSA-168249
Parasite infection R-HSA-9664407
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
GPCR downstream signalling R-HSA-388396
DAP12 interactions R-HSA-2172127
Diseases of Immune System R-HSA-5260271
G beta:gamma signalling through BTK R-HSA-8964315
Leishmania phagocytosis R-HSA-9664417
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
IRAK4 deficiency (TLR2/4) R-HSA-5603041
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Immune System R-HSA-168256
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
FCGR3A-mediated phagocytosis R-HSA-9664422
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by GPCR R-HSA-372790
Signaling by Rho GTPases R-HSA-194315
FCERI mediated Ca+2 mobilization R-HSA-2871809
DAP12 signaling R-HSA-2424491
Infectious disease R-HSA-5663205
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Adaptive Immune System R-HSA-1280218
Potential therapeutics for SARS R-HSA-9679191
Diseases associated with the TLR signaling cascade R-HSA-5602358
Class I MHC mediated antigen processing & presentation R-HSA-983169
Toll-like Receptor Cascades R-HSA-168898
Leishmania infection R-HSA-9658195
RHO GTPase Effectors R-HSA-195258
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G alpha (12/13) signalling events R-HSA-416482
MyD88 deficiency (TLR2/4) R-HSA-5602498
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SARS-CoV Infections R-HSA-9679506
ER-Phagosome pathway R-HSA-1236974
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Antigen processing-Cross presentation R-HSA-1236975
G-protein beta:gamma signalling R-HSA-397795
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Diseases associated with the TLR signaling cascade R-HSA-5602358
Adaptive Immune System R-HSA-1280218
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
FCGR3A-mediated phagocytosis R-HSA-9664422
G-protein beta:gamma signalling R-HSA-397795
Signaling by Rho GTPases R-HSA-194315
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Disease R-HSA-1643685
G beta:gamma signalling through BTK R-HSA-8964315
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by GPCR R-HSA-372790
Infectious disease R-HSA-5663205
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
SARS-CoV Infections R-HSA-9679506
Immune System R-HSA-168256
Potential therapeutics for SARS R-HSA-9679191
DAP12 signaling R-HSA-2424491
MyD88 deficiency (TLR2/4) R-HSA-5602498
Leishmania infection R-HSA-9658195
FCERI mediated Ca+2 mobilization R-HSA-2871809
Signal Transduction R-HSA-162582
Parasite infection R-HSA-9664407
Toll-like Receptor Cascades R-HSA-168898
ER-Phagosome pathway R-HSA-1236974
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Diseases of Immune System R-HSA-5260271
Antigen processing-Cross presentation R-HSA-1236975
DAP12 interactions R-HSA-2172127
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Leishmania phagocytosis R-HSA-9664417
G alpha (12/13) signalling events R-HSA-416482
G alpha (q) signalling events R-HSA-416476
IRAK4 deficiency (TLR2/4) R-HSA-5603041
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RHO GTPase Effectors R-HSA-195258
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Innate Immune System R-HSA-168249
GPCR downstream signalling R-HSA-388396
Adaptive Immune System R-HSA-1280218
Leishmania infection R-HSA-9658195
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll-like Receptor Cascades R-HSA-168898
Signaling by GPCR R-HSA-372790
DAP12 interactions R-HSA-2172127
G-protein beta:gamma signalling R-HSA-397795
DAP12 signaling R-HSA-2424491
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Diseases associated with the TLR signaling cascade R-HSA-5602358
Disease R-HSA-1643685
Diseases of Immune System R-HSA-5260271
GPCR downstream signalling R-HSA-388396
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
FCERI mediated Ca+2 mobilization R-HSA-2871809
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Rho GTPases R-HSA-194315
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
G alpha (12/13) signalling events R-HSA-416482
Signal Transduction R-HSA-162582
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV Infections R-HSA-9679506
Parasite infection R-HSA-9664407
IRAK4 deficiency (TLR2/4) R-HSA-5603041
Infectious disease R-HSA-5663205
Leishmania phagocytosis R-HSA-9664417
Immune System R-HSA-168256
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Innate Immune System R-HSA-168249
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
FCGR3A-mediated phagocytosis R-HSA-9664422
G alpha (q) signalling events R-HSA-416476
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Class I MHC mediated antigen processing & presentation R-HSA-983169
ER-Phagosome pathway R-HSA-1236974
MyD88 deficiency (TLR2/4) R-HSA-5602498
RHO GTPase Effectors R-HSA-195258
G beta:gamma signalling through BTK R-HSA-8964315
Antigen processing-Cross presentation R-HSA-1236975
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Antigen processing-Cross presentation R-HSA-1236975
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
SARS-CoV Infections R-HSA-9679506
Potential therapeutics for SARS R-HSA-9679191
Toll-like Receptor Cascades R-HSA-168898
RHO GTPase Effectors R-HSA-195258
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G beta:gamma signalling through BTK R-HSA-8964315
Diseases of Immune System R-HSA-5260271
G alpha (q) signalling events R-HSA-416476
G alpha (12/13) signalling events R-HSA-416482
Diseases associated with the TLR signaling cascade R-HSA-5602358
FCGR3A-mediated phagocytosis R-HSA-9664422
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Class I MHC mediated antigen processing & presentation R-HSA-983169
Leishmania phagocytosis R-HSA-9664417
IRAK4 deficiency (TLR2/4) R-HSA-5603041
G-protein beta:gamma signalling R-HSA-397795
Leishmania infection R-HSA-9658195
DAP12 interactions R-HSA-2172127
FCERI mediated Ca+2 mobilization R-HSA-2871809
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Rho GTPases R-HSA-194315
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
ER-Phagosome pathway R-HSA-1236974
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MyD88 deficiency (TLR2/4) R-HSA-5602498
Signaling by GPCR R-HSA-372790
Parasite infection R-HSA-9664407
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Adaptive Immune System R-HSA-1280218
DAP12 signaling R-HSA-2424491
Innate Immune System R-HSA-168249
GPCR downstream signalling R-HSA-388396
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
DAP12 interactions R-HSA-2172127
G alpha (q) signalling events R-HSA-416476
Infectious disease R-HSA-5663205
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Innate Immune System R-HSA-168249
Class I MHC mediated antigen processing & presentation R-HSA-983169
Signaling by the B Cell Receptor (BCR) R-HSA-983705
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
G alpha (12/13) signalling events R-HSA-416482
Leishmania phagocytosis R-HSA-9664417
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
SARS-CoV Infections R-HSA-9679506
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
DAP12 signaling R-HSA-2424491
Adaptive Immune System R-HSA-1280218
Potential therapeutics for SARS R-HSA-9679191
Parasite infection R-HSA-9664407
G-protein beta:gamma signalling R-HSA-397795
GPCR downstream signalling R-HSA-388396
Diseases of Immune System R-HSA-5260271
Diseases associated with the TLR signaling cascade R-HSA-5602358
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Leishmania infection R-HSA-9658195
Disease R-HSA-1643685
Antigen processing-Cross presentation R-HSA-1236975
MyD88 deficiency (TLR2/4) R-HSA-5602498
Toll-like Receptor Cascades R-HSA-168898
Signaling by GPCR R-HSA-372790
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Signaling by Rho GTPases R-HSA-194315
Immune System R-HSA-168256
FCGR3A-mediated phagocytosis R-HSA-9664422
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
G beta:gamma signalling through BTK R-HSA-8964315
FCERI mediated Ca+2 mobilization R-HSA-2871809
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
IRAK4 deficiency (TLR2/4) R-HSA-5603041
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RHO GTPase Effectors R-HSA-195258
ER-Phagosome pathway R-HSA-1236974
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Rho GTPases R-HSA-194315
Infectious disease R-HSA-5663205
Potential therapeutics for SARS R-HSA-9679191
Diseases associated with the TLR signaling cascade R-HSA-5602358
Class I MHC mediated antigen processing & presentation R-HSA-983169
G alpha (q) signalling events R-HSA-416476
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Leishmania phagocytosis R-HSA-9664417
Diseases of Immune System R-HSA-5260271
Signaling by GPCR R-HSA-372790
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Parasite infection R-HSA-9664407
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FCERI mediated Ca+2 mobilization R-HSA-2871809
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
DAP12 signaling R-HSA-2424491
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
ER-Phagosome pathway R-HSA-1236974
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
IRAK4 deficiency (TLR2/4) R-HSA-5603041
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
G beta:gamma signalling through BTK R-HSA-8964315
FCGR3A-mediated phagocytosis R-HSA-9664422
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
SARS-CoV Infections R-HSA-9679506
GPCR downstream signalling R-HSA-388396
G alpha (12/13) signalling events R-HSA-416482
Innate Immune System R-HSA-168249
G-protein beta:gamma signalling R-HSA-397795
DAP12 interactions R-HSA-2172127
Antigen processing-Cross presentation R-HSA-1236975
Toll-like Receptor Cascades R-HSA-168898
MyD88 deficiency (TLR2/4) R-HSA-5602498
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
RHO GTPase Effectors R-HSA-195258
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Disease R-HSA-1643685
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Leishmania infection R-HSA-9658195
Immune System R-HSA-168256
MyD88 deficiency (TLR2/4) R-HSA-5602498
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
Diseases associated with the TLR signaling cascade R-HSA-5602358
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
RHO GTPase Effectors R-HSA-195258
Antigen processing-Cross presentation R-HSA-1236975
Infectious disease R-HSA-5663205
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Toll-like Receptor Cascades R-HSA-168898
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Potential therapeutics for SARS R-HSA-9679191
Parasite infection R-HSA-9664407
Signaling by the B Cell Receptor (BCR) R-HSA-983705
GPCR downstream signalling R-HSA-388396
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
DAP12 signaling R-HSA-2424491
G alpha (q) signalling events R-HSA-416476
IRAK4 deficiency (TLR2/4) R-HSA-5603041
Diseases of Immune System R-HSA-5260271
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Leishmania phagocytosis R-HSA-9664417
Signaling by Rho GTPases R-HSA-194315
G alpha (12/13) signalling events R-HSA-416482
FCERI mediated Ca+2 mobilization R-HSA-2871809
Class I MHC mediated antigen processing & presentation R-HSA-983169
G-protein beta:gamma signalling R-HSA-397795
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by GPCR R-HSA-372790
SARS-CoV Infections R-HSA-9679506
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
ER-Phagosome pathway R-HSA-1236974
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DAP12 interactions R-HSA-2172127
G beta:gamma signalling through BTK R-HSA-8964315
Immune System R-HSA-168256
Leishmania infection R-HSA-9658195

Expression Atlas ENSG00000010671
LRG display in Ensembl gene LRG_128
NCBI gene (formerly Entrezgene) 695
GeneCards 1133
HGNC Symbol HGNC:1133
MIM gene 300300
MIM morbid 307200
UniProtKB Gene Name Q5JY90
WikiGene 695
Gene: PDGFRB
Ensembl ID : ENSG00000113721
Description: platelet derived growth factor receptor beta
Gene Synonyms: CD140B,JTK12,PDGFR,PDGFR1
40 APIs:
247 Possible Orthologues:

Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Downstream signal transduction R-HSA-186763
Signaling by PDGF R-HSA-186797
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAF/MAP kinase cascade R-HSA-5673001
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by PDGF R-HSA-186797
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Downstream signal transduction R-HSA-186763
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Downstream signal transduction R-HSA-186763
MAPK family signaling cascades R-HSA-5683057
Signaling by PDGF R-HSA-186797
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Negative regulation of the PI3K/AKT network R-HSA-199418
PIP3 activates AKT signaling R-HSA-1257604
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
MAPK1/MAPK3 signaling R-HSA-5684996
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGF R-HSA-186797
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signal transduction R-HSA-186763
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by PDGF R-HSA-186797
Downstream signal transduction R-HSA-186763
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
Downstream signal transduction R-HSA-186763
Disease R-HSA-1643685
Signaling by PDGF R-HSA-186797
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by PDGF R-HSA-186797
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Downstream signal transduction R-HSA-186763
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF/MAP kinase cascade R-HSA-5673001
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by PDGF R-HSA-186797
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Intracellular signaling by second messengers R-HSA-9006925
Downstream signal transduction R-HSA-186763
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Signaling by PDGF R-HSA-186797
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signal transduction R-HSA-186763
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RAF/MAP kinase cascade R-HSA-5673001
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK family signaling cascades R-HSA-5683057
Signaling by PDGF R-HSA-186797
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signal transduction R-HSA-186763
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604

Expression Atlas ENSG00000113721
NCBI gene (formerly Entrezgene) 5159
GeneCards 8804
HGNC Symbol HGNC:8804
MIM gene 173410
MIM morbid 616592
UniProtKB Gene Name P09619
WikiGene 5159
Gene: MAPK9
Ensembl ID : ENSG00000050748
Description: mitogen-activated protein kinase 9
Gene Synonyms: JNK2,P54A,PRKM9,SAPK
3 APIs:
219 Possible Orthologues:

Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Activation of the AP-1 family of transcription factors R-HSA-450341
MyD88-independent TLR4 cascade R-HSA-166166
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Immune System R-HSA-168256
Oxidative Stress Induced Senescence R-HSA-2559580
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-17 signaling R-HSA-448424
MyD88 cascade initiated on plasma membrane R-HSA-975871
Innate Immune System R-HSA-168249
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Interleukins R-HSA-449147
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular Senescence R-HSA-2559583
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
FCERI mediated MAPK activation R-HSA-2871796
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll-like Receptor Cascades R-HSA-168898
MAP kinase activation R-HSA-450294
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
FCERI mediated MAPK activation R-HSA-2871796
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MAP kinase activation R-HSA-450294
Toll-like Receptor Cascades R-HSA-168898
Cytokine Signaling in Immune system R-HSA-1280215
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Activation of the AP-1 family of transcription factors R-HSA-450341
MyD88 dependent cascade initiated on endosome R-HSA-975155
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stress R-HSA-2262752
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-17 signaling R-HSA-448424
Cellular responses to stimuli R-HSA-8953897
Cellular Senescence R-HSA-2559583
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cellular responses to stress R-HSA-2262752
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88 dependent cascade initiated on endosome R-HSA-975155
MyD88-independent TLR4 cascade R-HSA-166166
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Interleukin-17 signaling R-HSA-448424
Cellular Senescence R-HSA-2559583
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cytokine Signaling in Immune system R-HSA-1280215
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stimuli R-HSA-8953897
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll-like Receptor Cascades R-HSA-168898
Innate Immune System R-HSA-168249
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MAP kinase activation R-HSA-450294
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Activation of the AP-1 family of transcription factors R-HSA-450341
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cytokine Signaling in Immune system R-HSA-1280215
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Interleukin-17 signaling R-HSA-448424
Oxidative Stress Induced Senescence R-HSA-2559580
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88 dependent cascade initiated on endosome R-HSA-975155
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
FCERI mediated MAPK activation R-HSA-2871796
Activation of the AP-1 family of transcription factors R-HSA-450341
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stimuli R-HSA-8953897
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll-like Receptor Cascades R-HSA-168898
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MAP kinase activation R-HSA-450294
Signaling by Interleukins R-HSA-449147
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stress R-HSA-2262752
MAP kinase activation R-HSA-450294
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cellular Senescence R-HSA-2559583
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Immune System R-HSA-168256
Activation of the AP-1 family of transcription factors R-HSA-450341
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88 cascade initiated on plasma membrane R-HSA-975871
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Interleukin-17 signaling R-HSA-448424
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Interleukins R-HSA-449147
Cellular responses to stimuli R-HSA-8953897
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cytokine Signaling in Immune system R-HSA-1280215
MyD88-independent TLR4 cascade R-HSA-166166
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
FCERI mediated MAPK activation R-HSA-2871796
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Interleukin-17 signaling R-HSA-448424
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll-like Receptor Cascades R-HSA-168898
MyD88 dependent cascade initiated on endosome R-HSA-975155
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cytokine Signaling in Immune system R-HSA-1280215
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MAP kinase activation R-HSA-450294
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88-independent TLR4 cascade R-HSA-166166
Cellular Senescence R-HSA-2559583
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cellular responses to stress R-HSA-2262752
MAP kinase activation R-HSA-450294
MyD88 cascade initiated on plasma membrane R-HSA-975871
Activation of the AP-1 family of transcription factors R-HSA-450341
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Immune System R-HSA-168256
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88 dependent cascade initiated on endosome R-HSA-975155
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Interleukin-17 signaling R-HSA-448424
Cellular responses to stimuli R-HSA-8953897
FCERI mediated MAPK activation R-HSA-2871796
Signaling by Interleukins R-HSA-449147
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88-independent TLR4 cascade R-HSA-166166
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Innate Immune System R-HSA-168249
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Activation of the AP-1 family of transcription factors R-HSA-450341
Interleukin-17 signaling R-HSA-448424
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stress R-HSA-2262752
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
FCERI mediated MAPK activation R-HSA-2871796
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88-independent TLR4 cascade R-HSA-166166
Immune System R-HSA-168256
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by Interleukins R-HSA-449147
Oxidative Stress Induced Senescence R-HSA-2559580
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular Senescence R-HSA-2559583
MAP kinase activation R-HSA-450294
Toll-like Receptor Cascades R-HSA-168898
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular responses to stimuli R-HSA-8953897
Innate Immune System R-HSA-168249
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Innate Immune System R-HSA-168249
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Immune System R-HSA-168256
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
FCERI mediated MAPK activation R-HSA-2871796
Cytokine Signaling in Immune system R-HSA-1280215
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular Senescence R-HSA-2559583
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stress R-HSA-2262752
Signaling by Interleukins R-HSA-449147
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular responses to stimuli R-HSA-8953897
MyD88 cascade initiated on plasma membrane R-HSA-975871
Activation of the AP-1 family of transcription factors R-HSA-450341
MAP kinase activation R-HSA-450294
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88-independent TLR4 cascade R-HSA-166166
Toll-like Receptor Cascades R-HSA-168898

Expression Atlas ENSG00000050748
NCBI gene (formerly Entrezgene) 5601
GeneCards 6886
HGNC Symbol HGNC:6886
MIM gene 602896
UniProtKB Gene Name P45984
WikiGene 5601
Gene: MAP3K13
Ensembl ID : ENSG00000073803
Description: mitogen-activated protein kinase kinase kinase 13
Gene Synonyms: LZK,MEKK13
1 APIs:
201 Possible Orthologues:

Expression Atlas ENSG00000073803
NCBI gene (formerly Entrezgene) 9175
GeneCards 6852
HGNC Symbol HGNC:6852
MIM gene 604915
UniProtKB Gene Name O43283
WikiGene 9175
Gene: FGFR3
Ensembl ID : ENSG00000068078
Description: fibroblast growth factor receptor 3
Gene Synonyms: ACH,CD333,CEK2,JTK4
24 APIs:
196 Possible Orthologues:

IGF1R signaling cascade R-HSA-2428924
t(4;14) translocations of FGFR3 R-HSA-2033515
IRS-related events triggered by IGF1R R-HSA-2428928
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR3 in disease R-HSA-5655332
Disease R-HSA-1643685
IGF1R signaling cascade R-HSA-2428924
Negative regulation of FGFR3 signaling R-HSA-5654732
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR3 fusions in cancer R-HSA-8853334
Insulin receptor signalling cascade R-HSA-74751
FGFR3b ligand binding and activation R-HSA-190371
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by FGFR R-HSA-190236
FGFR3 ligand binding and activation R-HSA-190239
PI3K Cascade R-HSA-109704
Signaling by FGFR in disease R-HSA-1226099
FGFR3 mutant receptor activation R-HSA-2033514
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227
FGFR3c ligand binding and activation R-HSA-190372
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Insulin receptor R-HSA-74752
PI-3K cascade:FGFR3 R-HSA-5654710
IRS-mediated signalling R-HSA-112399
SHC-mediated cascade:FGFR3 R-HSA-5654704
Signaling by activated point mutants of FGFR3 R-HSA-1839130
Signaling by FGFR3 R-HSA-5654741
MAPK1/MAPK3 signaling R-HSA-5684996
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
MAPK family signaling cascades R-HSA-5683057
FRS-mediated FGFR3 signaling R-HSA-5654706
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR in disease R-HSA-1226099
Signaling by FGFR3 in disease R-HSA-5655332
FRS-mediated FGFR3 signaling R-HSA-5654706
Signaling by Insulin receptor R-HSA-74752
FGFR3 mutant receptor activation R-HSA-2033514
Signaling by FGFR R-HSA-190236
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK family signaling cascades R-HSA-5683057
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K Cascade R-HSA-109704
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
Negative regulation of the PI3K/AKT network R-HSA-199418
RAF/MAP kinase cascade R-HSA-5673001
PI-3K cascade:FGFR3 R-HSA-5654710
FGFR3 ligand binding and activation R-HSA-190239
t(4;14) translocations of FGFR3 R-HSA-2033515
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227
Signaling by FGFR3 fusions in cancer R-HSA-8853334
SHC-mediated cascade:FGFR3 R-HSA-5654704
FGFR3c ligand binding and activation R-HSA-190372
Downstream signaling of activated FGFR3 R-HSA-5654708
FGFR3b ligand binding and activation R-HSA-190371
Signaling by activated point mutants of FGFR3 R-HSA-1839130
IRS-related events triggered by IGF1R R-HSA-2428928
IRS-mediated signalling R-HSA-112399
MAPK1/MAPK3 signaling R-HSA-5684996
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR3 R-HSA-5654741
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
IGF1R signaling cascade R-HSA-2428924
PI3K/AKT Signaling in Cancer R-HSA-2219528
Negative regulation of FGFR3 signaling R-HSA-5654732
FGFR3c ligand binding and activation R-HSA-190372
Signaling by activated point mutants of FGFR3 R-HSA-1839130
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
SHC-mediated cascade:FGFR3 R-HSA-5654704
Disease R-HSA-1643685
IGF1R signaling cascade R-HSA-2428924
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
FGFR3 ligand binding and activation R-HSA-190239
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR3 fusions in cancer R-HSA-8853334
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI-3K cascade:FGFR3 R-HSA-5654710
Signaling by FGFR3 R-HSA-5654741
Signaling by FGFR3 in disease R-HSA-5655332
Negative regulation of the PI3K/AKT network R-HSA-199418
t(4;14) translocations of FGFR3 R-HSA-2033515
Signaling by FGFR in disease R-HSA-1226099
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
FGFR3 mutant receptor activation R-HSA-2033514
Signaling by Insulin receptor R-HSA-74752
Negative regulation of FGFR3 signaling R-HSA-5654732
FRS-mediated FGFR3 signaling R-HSA-5654706
IRS-related events triggered by IGF1R R-HSA-2428928
FGFR3b ligand binding and activation R-HSA-190371
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR R-HSA-190236
IRS-mediated signalling R-HSA-112399
RAF/MAP kinase cascade R-HSA-5673001
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227
Downstream signaling of activated FGFR3 R-HSA-5654708
Insulin receptor signalling cascade R-HSA-74751
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K Cascade R-HSA-109704
Signaling by FGFR3 fusions in cancer R-HSA-8853334
FGFR3b ligand binding and activation R-HSA-190371
Signaling by FGFR3 in disease R-HSA-5655332
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227
Downstream signaling of activated FGFR3 R-HSA-5654708
FGFR3 mutant receptor activation R-HSA-2033514
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
Signaling by FGFR3 R-HSA-5654741
Insulin receptor signalling cascade R-HSA-74751
IRS-related events triggered by IGF1R R-HSA-2428928
PI3K Cascade R-HSA-109704
PI3K/AKT Signaling in Cancer R-HSA-2219528
Negative regulation of FGFR3 signaling R-HSA-5654732
Intracellular signaling by second messengers R-HSA-9006925
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Insulin receptor R-HSA-74752
FRS-mediated FGFR3 signaling R-HSA-5654706
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR R-HSA-190236
PI-3K cascade:FGFR3 R-HSA-5654710
t(4;14) translocations of FGFR3 R-HSA-2033515
Disease R-HSA-1643685
FGFR3 ligand binding and activation R-HSA-190239
Signaling by FGFR in disease R-HSA-1226099
FGFR3c ligand binding and activation R-HSA-190372
Signaling by activated point mutants of FGFR3 R-HSA-1839130
MAPK family signaling cascades R-HSA-5683057
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IGF1R signaling cascade R-HSA-2428924
SHC-mediated cascade:FGFR3 R-HSA-5654704
IRS-mediated signalling R-HSA-112399
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227
FGFR3c ligand binding and activation R-HSA-190372
Signal Transduction R-HSA-162582
SHC-mediated cascade:FGFR3 R-HSA-5654704
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Downstream signaling of activated FGFR3 R-HSA-5654708
Intracellular signaling by second messengers R-HSA-9006925
FGFR3b ligand binding and activation R-HSA-190371
PI3K Cascade R-HSA-109704
FRS-mediated FGFR3 signaling R-HSA-5654706
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by FGFR in disease R-HSA-1226099
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK1/MAPK3 signaling R-HSA-5684996
t(4;14) translocations of FGFR3 R-HSA-2033515
Signaling by Insulin receptor R-HSA-74752
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by FGFR3 R-HSA-5654741
FGFR3 mutant receptor activation R-HSA-2033514
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR R-HSA-190236
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI-3K cascade:FGFR3 R-HSA-5654710
MAPK family signaling cascades R-HSA-5683057
FGFR3 ligand binding and activation R-HSA-190239
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR3 in disease R-HSA-5655332
Disease R-HSA-1643685
Signaling by activated point mutants of FGFR3 R-HSA-1839130
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
IRS-related events triggered by IGF1R R-HSA-2428928
IRS-mediated signalling R-HSA-112399
Signaling by FGFR3 fusions in cancer R-HSA-8853334
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR3 in disease R-HSA-5655332
FRS-mediated FGFR3 signaling R-HSA-5654706
Signaling by FGFR3 R-HSA-5654741
Signaling by FGFR3 fusions in cancer R-HSA-8853334
Signaling by FGFR R-HSA-190236
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS-mediated signalling R-HSA-112399
t(4;14) translocations of FGFR3 R-HSA-2033515
Negative regulation of FGFR3 signaling R-HSA-5654732
Disease R-HSA-1643685
Signaling by Insulin receptor R-HSA-74752
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR in disease R-HSA-1226099
MAPK family signaling cascades R-HSA-5683057
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by activated point mutants of FGFR3 R-HSA-1839130
FGFR3 ligand binding and activation R-HSA-190239
SHC-mediated cascade:FGFR3 R-HSA-5654704
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signal Transduction R-HSA-162582
FGFR3 mutant receptor activation R-HSA-2033514
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAF/MAP kinase cascade R-HSA-5673001
FGFR3b ligand binding and activation R-HSA-190371
PIP3 activates AKT signaling R-HSA-1257604
PI3K Cascade R-HSA-109704
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FGFR3c ligand binding and activation R-HSA-190372
IGF1R signaling cascade R-HSA-2428924
Downstream signaling of activated FGFR3 R-HSA-5654708
IRS-related events triggered by IGF1R R-HSA-2428928
PI-3K cascade:FGFR3 R-HSA-5654710
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227
Downstream signaling of activated FGFR3 R-HSA-5654708
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signal Transduction R-HSA-162582
PI3K Cascade R-HSA-109704
Signaling by activated point mutants of FGFR3 R-HSA-1839130
Signaling by FGFR in disease R-HSA-1226099
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR R-HSA-190236
Disease R-HSA-1643685
PI-3K cascade:FGFR3 R-HSA-5654710
SHC-mediated cascade:FGFR3 R-HSA-5654704
FGFR3 ligand binding and activation R-HSA-190239
PIP3 activates AKT signaling R-HSA-1257604
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FGFR3c ligand binding and activation R-HSA-190372
FGFR3 mutant receptor activation R-HSA-2033514
Negative regulation of the PI3K/AKT network R-HSA-199418
IRS-mediated signalling R-HSA-112399
RAF/MAP kinase cascade R-HSA-5673001
t(4;14) translocations of FGFR3 R-HSA-2033515
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of FGFR3 signaling R-HSA-5654732
FGFR3b ligand binding and activation R-HSA-190371
Signaling by FGFR3 fusions in cancer R-HSA-8853334
FRS-mediated FGFR3 signaling R-HSA-5654706
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR3 R-HSA-5654741
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR3 in disease R-HSA-5655332
MAPK family signaling cascades R-HSA-5683057
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR in disease R-HSA-1226099
IGF1R signaling cascade R-HSA-2428924
Disease R-HSA-1643685
FRS-mediated FGFR3 signaling R-HSA-5654706
PI3K Cascade R-HSA-109704
Negative regulation of the PI3K/AKT network R-HSA-199418
RAF/MAP kinase cascade R-HSA-5673001
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
IRS-mediated signalling R-HSA-112399
Negative regulation of FGFR3 signaling R-HSA-5654732
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IRS-related events triggered by IGF1R R-HSA-2428928
PIP3 activates AKT signaling R-HSA-1257604
Signaling by FGFR3 in disease R-HSA-5655332
Signaling by activated point mutants of FGFR3 R-HSA-1839130
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK family signaling cascades R-HSA-5683057
Downstream signaling of activated FGFR3 R-HSA-5654708
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by FGFR3 fusions in cancer R-HSA-8853334
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI-3K cascade:FGFR3 R-HSA-5654710
t(4;14) translocations of FGFR3 R-HSA-2033515
Signaling by FGFR3 R-HSA-5654741
Insulin receptor signalling cascade R-HSA-74751
FGFR3 ligand binding and activation R-HSA-190239
FGFR3c ligand binding and activation R-HSA-190372
SHC-mediated cascade:FGFR3 R-HSA-5654704
FGFR3 mutant receptor activation R-HSA-2033514
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FGFR3b ligand binding and activation R-HSA-190371
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR R-HSA-190236
Signaling by Insulin receptor R-HSA-74752
FGFR3b ligand binding and activation R-HSA-190371
SHC-mediated cascade:FGFR3 R-HSA-5654704
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227
Signaling by FGFR3 R-HSA-5654741
PI3K Cascade R-HSA-109704
IRS-related events triggered by IGF1R R-HSA-2428928
IRS-mediated signalling R-HSA-112399
FGFR3 mutant receptor activation R-HSA-2033514
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR R-HSA-190236
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR3 in disease R-HSA-5655332
Disease R-HSA-1643685
IGF1R signaling cascade R-HSA-2428924
PI3K/AKT Signaling in Cancer R-HSA-2219528
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling of activated FGFR3 R-HSA-5654708
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI-3K cascade:FGFR3 R-HSA-5654710
Negative regulation of FGFR3 signaling R-HSA-5654732
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR3 fusions in cancer R-HSA-8853334
FGFR3 ligand binding and activation R-HSA-190239
t(4;14) translocations of FGFR3 R-HSA-2033515
Signaling by activated point mutants of FGFR3 R-HSA-1839130
Insulin receptor signalling cascade R-HSA-74751
Signaling by Insulin receptor R-HSA-74752
FRS-mediated FGFR3 signaling R-HSA-5654706
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR in disease R-HSA-1226099
FGFR3c ligand binding and activation R-HSA-190372
FGFR3 mutant receptor activation R-HSA-2033514
Signaling by FGFR3 R-HSA-5654741
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR in disease R-HSA-1226099
RAF/MAP kinase cascade R-HSA-5673001
FRS-mediated FGFR3 signaling R-HSA-5654706
FGFR3b ligand binding and activation R-HSA-190371
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227
Signaling by FGFR3 fusions in cancer R-HSA-8853334
PI-3K cascade:FGFR3 R-HSA-5654710
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by activated point mutants of FGFR3 R-HSA-1839130
IGF1R signaling cascade R-HSA-2428924
Negative regulation of FGFR3 signaling R-HSA-5654732
t(4;14) translocations of FGFR3 R-HSA-2033515
Signaling by FGFR3 in disease R-HSA-5655332
IRS-mediated signalling R-HSA-112399
PI3K Cascade R-HSA-109704
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR R-HSA-190236
Insulin receptor signalling cascade R-HSA-74751
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
FGFR3c ligand binding and activation R-HSA-190372
SHC-mediated cascade:FGFR3 R-HSA-5654704
FGFR3 ligand binding and activation R-HSA-190239
MAPK1/MAPK3 signaling R-HSA-5684996
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS-related events triggered by IGF1R R-HSA-2428928
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by Insulin receptor R-HSA-74752

Expression Atlas ENSG00000068078
LRG display in Ensembl gene LRG_1021
NCBI gene (formerly Entrezgene) 2261
GeneCards 3690
HGNC Symbol HGNC:3690
MIM gene 134934
MIM morbid 616482
UniProtKB Gene Name Q96T34
WikiGene 2261
Ensembl ID : ENSG00000162889
Description: MAPK activated protein kinase 2
Gene Synonyms: MK2
1 APIs:
240 Possible Orthologues:

Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism R-HSA-1430728
Immune System R-HSA-168256
MyD88 dependent cascade initiated on endosome R-HSA-975155
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Cellular responses to stress R-HSA-2262752
Oxidative Stress Induced Senescence R-HSA-2559580
Interleukin-17 signaling R-HSA-448424
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Fatty acid metabolism R-HSA-8978868
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
MAP kinase activation R-HSA-450294
CREB phosphorylation R-HSA-199920
Signalling to RAS R-HSA-167044
Signaling by NTRKs R-HSA-166520
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll-like Receptor Cascades R-HSA-168898
MyD88 cascade initiated on plasma membrane R-HSA-975871
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Metabolism of lipids R-HSA-556833
Signaling by NTRK1 (TRKA) R-HSA-187037
Cellular Senescence R-HSA-2559583
Cytokine Signaling in Immune system R-HSA-1280215
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Metabolism of RNA R-HSA-8953854
Innate Immune System R-HSA-168249
MyD88-independent TLR4 cascade R-HSA-166166
Cellular response to heat stress R-HSA-3371556
TNF signaling R-HSA-75893
Arachidonic acid metabolism R-HSA-2142753
p38MAPK events R-HSA-171007
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cellular responses to stimuli R-HSA-8953897
Signalling to ERKs R-HSA-187687
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by VEGF R-HSA-194138
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Regulation of TNFR1 signaling R-HSA-5357905
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by NTRKs R-HSA-166520
Metabolism R-HSA-1430728
Toll-like Receptor Cascades R-HSA-168898
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
VEGFA-VEGFR2 Pathway R-HSA-4420097
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
MyD88 dependent cascade initiated on endosome R-HSA-975155
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signalling to RAS R-HSA-167044
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
MAP kinase activation R-HSA-450294
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by VEGF R-HSA-194138
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Death Receptor Signaling R-HSA-73887
Innate Immune System R-HSA-168249
Signalling to ERKs R-HSA-187687
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Fatty acid metabolism R-HSA-8978868
Arachidonic acid metabolism R-HSA-2142753
TNF signaling R-HSA-75893
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Interleukin-17 signaling R-HSA-448424
Immune System R-HSA-168256
MyD88 cascade initiated on plasma membrane R-HSA-975871
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Metabolism of RNA R-HSA-8953854
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular response to heat stress R-HSA-3371556
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
p38MAPK events R-HSA-171007
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Metabolism of lipids R-HSA-556833
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Oxidative Stress Induced Senescence R-HSA-2559580
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Regulation of TNFR1 signaling R-HSA-5357905
Signaling by Interleukins R-HSA-449147
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
CREB phosphorylation R-HSA-199920
Signaling by Interleukins R-HSA-449147
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Immune System R-HSA-168256
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Cytokine Signaling in Immune system R-HSA-1280215
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Interleukin-17 signaling R-HSA-448424
Metabolism of lipids R-HSA-556833
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Metabolism of RNA R-HSA-8953854
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Metabolism R-HSA-1430728
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stimuli R-HSA-8953897
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by NTRK1 (TRKA) R-HSA-187037
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by VEGF R-HSA-194138
MAP kinase activation R-HSA-450294
VEGFA-VEGFR2 Pathway R-HSA-4420097
MyD88 dependent cascade initiated on endosome R-HSA-975155
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signalling to ERKs R-HSA-187687
Signal Transduction R-HSA-162582
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
p38MAPK events R-HSA-171007
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Innate Immune System R-HSA-168249
Cellular Senescence R-HSA-2559583
Signaling by NTRKs R-HSA-166520
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Arachidonic acid metabolism R-HSA-2142753
Cellular responses to stress R-HSA-2262752
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll-like Receptor Cascades R-HSA-168898
Fatty acid metabolism R-HSA-8978868
CREB phosphorylation R-HSA-199920
Death Receptor Signaling R-HSA-73887
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TNF signaling R-HSA-75893
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signalling to RAS R-HSA-167044
Cellular Senescence R-HSA-2559583
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
Toll-like Receptor Cascades R-HSA-168898
Arachidonic acid metabolism R-HSA-2142753
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88-independent TLR4 cascade R-HSA-166166
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Metabolism of RNA R-HSA-8953854
Signaling by NTRK1 (TRKA) R-HSA-187037
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Immune System R-HSA-168256
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Oxidative Stress Induced Senescence R-HSA-2559580
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAP kinase activation R-HSA-450294
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by NTRKs R-HSA-166520
p38MAPK events R-HSA-171007
CREB phosphorylation R-HSA-199920
Fatty acid metabolism R-HSA-8978868
Signaling by VEGF R-HSA-194138
Regulation of TNFR1 signaling R-HSA-5357905
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Cellular responses to stress R-HSA-2262752
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
TNF signaling R-HSA-75893
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Cellular response to heat stress R-HSA-3371556
Signal Transduction R-HSA-162582
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Interleukin-17 signaling R-HSA-448424
Death Receptor Signaling R-HSA-73887
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
MyD88 cascade initiated on plasma membrane R-HSA-975871
Metabolism of lipids R-HSA-556833
Signalling to ERKs R-HSA-187687
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
VEGFA-VEGFR2 Pathway R-HSA-4420097
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signalling to RAS R-HSA-167044
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism R-HSA-1430728
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TNF signaling R-HSA-75893
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Immune System R-HSA-168256
Toll-like Receptor Cascades R-HSA-168898
Signaling by NTRKs R-HSA-166520
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signalling to ERKs R-HSA-187687
Arachidonic acid metabolism R-HSA-2142753
Cellular Senescence R-HSA-2559583
Regulation of TNFR1 signaling R-HSA-5357905
Cellular responses to stress R-HSA-2262752
VEGFA-VEGFR2 Pathway R-HSA-4420097
Interleukin-17 signaling R-HSA-448424
Signaling by NTRK1 (TRKA) R-HSA-187037
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Fatty acid metabolism R-HSA-8978868
Signaling by Interleukins R-HSA-449147
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signal Transduction R-HSA-162582
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Oxidative Stress Induced Senescence R-HSA-2559580
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Innate Immune System R-HSA-168249
Metabolism of RNA R-HSA-8953854
Signalling to RAS R-HSA-167044
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
CREB phosphorylation R-HSA-199920
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MAP kinase activation R-HSA-450294
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by VEGF R-HSA-194138
Cytokine Signaling in Immune system R-HSA-1280215
p38MAPK events R-HSA-171007
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MyD88-independent TLR4 cascade R-HSA-166166
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular response to heat stress R-HSA-3371556
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
MyD88 dependent cascade initiated on endosome R-HSA-975155
Arachidonic acid metabolism R-HSA-2142753
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
TNF signaling R-HSA-75893
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signaling by NTRKs R-HSA-166520
VEGFA-VEGFR2 Pathway R-HSA-4420097
Metabolism R-HSA-1430728
Fatty acid metabolism R-HSA-8978868
Cellular responses to stress R-HSA-2262752
Death Receptor Signaling R-HSA-73887
Signaling by VEGF R-HSA-194138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
p38MAPK events R-HSA-171007
Signalling to RAS R-HSA-167044
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Cellular Senescence R-HSA-2559583
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAP kinase activation R-HSA-450294
Regulation of TNFR1 signaling R-HSA-5357905
Signal Transduction R-HSA-162582
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 cascade initiated on plasma membrane R-HSA-975871
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Metabolism of lipids R-HSA-556833
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signalling to ERKs R-HSA-187687
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular responses to stimuli R-HSA-8953897
CREB phosphorylation R-HSA-199920
Metabolism of RNA R-HSA-8953854
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stress R-HSA-2262752
MAP kinase activation R-HSA-450294
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signalling to ERKs R-HSA-187687
Metabolism of lipids R-HSA-556833
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Innate Immune System R-HSA-168249
Interleukin-17 signaling R-HSA-448424
Signaling by NTRKs R-HSA-166520
Death Receptor Signaling R-HSA-73887
Cellular response to heat stress R-HSA-3371556
Signal Transduction R-HSA-162582
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Signaling by VEGF R-HSA-194138
Cellular Senescence R-HSA-2559583
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Fatty acid metabolism R-HSA-8978868
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Interleukins R-HSA-449147
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Immune System R-HSA-168256
Signalling to RAS R-HSA-167044
MyD88-independent TLR4 cascade R-HSA-166166
Metabolism of RNA R-HSA-8953854
Oxidative Stress Induced Senescence R-HSA-2559580
p38MAPK events R-HSA-171007
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
VEGFA-VEGFR2 Pathway R-HSA-4420097
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Metabolism R-HSA-1430728
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll-like Receptor Cascades R-HSA-168898
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Arachidonic acid metabolism R-HSA-2142753
Regulation of TNFR1 signaling R-HSA-5357905
CREB phosphorylation R-HSA-199920
TNF signaling R-HSA-75893
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Cellular responses to stimuli R-HSA-8953897
Signaling by VEGF R-HSA-194138
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signal Transduction R-HSA-162582
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Innate Immune System R-HSA-168249
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Metabolism of lipids R-HSA-556833
Signaling by NTRKs R-HSA-166520
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Interleukin-17 signaling R-HSA-448424
TNF signaling R-HSA-75893
Fatty acid metabolism R-HSA-8978868
Signaling by NTRK1 (TRKA) R-HSA-187037
Signalling to RAS R-HSA-167044
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
VEGFA-VEGFR2 Pathway R-HSA-4420097
MyD88-independent TLR4 cascade R-HSA-166166
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signalling to ERKs R-HSA-187687
MAP kinase activation R-HSA-450294
MyD88 dependent cascade initiated on endosome R-HSA-975155
Metabolism R-HSA-1430728
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cellular response to heat stress R-HSA-3371556
Arachidonic acid metabolism R-HSA-2142753
p38MAPK events R-HSA-171007
Toll-like Receptor Cascades R-HSA-168898
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of RNA R-HSA-8953854
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular Senescence R-HSA-2559583
Immune System R-HSA-168256
CREB phosphorylation R-HSA-199920
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Regulation of TNFR1 signaling R-HSA-5357905
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stress R-HSA-2262752
Oxidative Stress Induced Senescence R-HSA-2559580
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
Signaling by Interleukins R-HSA-449147
MyD88 dependent cascade initiated on endosome R-HSA-975155
Immune System R-HSA-168256
Toll-like Receptor Cascades R-HSA-168898
Regulation of TNFR1 signaling R-HSA-5357905
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
p38MAPK events R-HSA-171007
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Metabolism of lipids R-HSA-556833
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Arachidonic acid metabolism R-HSA-2142753
Cellular Senescence R-HSA-2559583
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Signaling by NTRK1 (TRKA) R-HSA-187037
Cellular response to heat stress R-HSA-3371556
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Death Receptor Signaling R-HSA-73887
Cellular responses to stress R-HSA-2262752
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signalling to RAS R-HSA-167044
Oxidative Stress Induced Senescence R-HSA-2559580
MyD88 cascade initiated on plasma membrane R-HSA-975871
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
MAP kinase activation R-HSA-450294
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
Signalling to ERKs R-HSA-187687
Fatty acid metabolism R-HSA-8978868
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
Signaling by VEGF R-HSA-194138
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
TNF signaling R-HSA-75893
Metabolism of RNA R-HSA-8953854
CREB phosphorylation R-HSA-199920
Signaling by NTRKs R-HSA-166520
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Arachidonic acid metabolism R-HSA-2142753
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Immune System R-HSA-168256
VEGFA-VEGFR2 Pathway R-HSA-4420097
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Death Receptor Signaling R-HSA-73887
MAP kinase activation R-HSA-450294
Signaling by NTRK1 (TRKA) R-HSA-187037
Signalling to ERKs R-HSA-187687
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
CREB phosphorylation R-HSA-199920
Signaling by NTRKs R-HSA-166520
Cellular response to heat stress R-HSA-3371556
Toll-like Receptor Cascades R-HSA-168898
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stress R-HSA-2262752
MyD88-independent TLR4 cascade R-HSA-166166
TNF signaling R-HSA-75893
MyD88 dependent cascade initiated on endosome R-HSA-975155
Regulation of TNFR1 signaling R-HSA-5357905
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
p38MAPK events R-HSA-171007
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Metabolism R-HSA-1430728
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
Interleukin-17 signaling R-HSA-448424
MyD88 cascade initiated on plasma membrane R-HSA-975871
Metabolism of RNA R-HSA-8953854
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by VEGF R-HSA-194138
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cytokine Signaling in Immune system R-HSA-1280215
Innate Immune System R-HSA-168249
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Cellular Senescence R-HSA-2559583
Signalling to RAS R-HSA-167044
Signal Transduction R-HSA-162582
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Metabolism of lipids R-HSA-556833
Fatty acid metabolism R-HSA-8978868
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164

Expression Atlas ENSG00000162889
NCBI gene (formerly Entrezgene) 9261
GeneCards 6887
HGNC Symbol HGNC:6887
MIM gene 602006
UniProtKB Gene Name P49137
WikiGene 9261