Gene: NCSTN
Ensembl ID : ENSG00000162736
Description: nicastrin
Gene Synonyms: APH2,KIAA0253
5 APIs:
204 Possible Orthologues:

Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Death Receptor Signaling R-HSA-73887
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH3 R-HSA-9012852
Nervous system development R-HSA-9675108
Amyloid fiber formation R-HSA-977225
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 in Cancer R-HSA-2644603
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulated proteolysis of p75NTR R-HSA-193692
Disease R-HSA-1643685
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 R-HSA-1980143
p75 NTR receptor-mediated signalling R-HSA-193704
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Neutrophil degranulation R-HSA-6798695
EPH-Ephrin signaling R-HSA-2682334
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Immune System R-HSA-168256
Signaling by ERBB4 R-HSA-1236394
Innate Immune System R-HSA-168249
Axon guidance R-HSA-422475
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH4 R-HSA-9013694
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by ERBB4 R-HSA-1236394
Neutrophil degranulation R-HSA-6798695
Amyloid fiber formation R-HSA-977225
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 in Cancer R-HSA-2644603
Death Receptor Signaling R-HSA-73887
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Developmental Biology R-HSA-1266738
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Innate Immune System R-HSA-168249
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Immune System R-HSA-168256
Nuclear signaling by ERBB4 R-HSA-1251985
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH3 R-HSA-9012852
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Nervous system development R-HSA-9675108
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH3 R-HSA-9012852
EPH-Ephrin signaling R-HSA-2682334
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 R-HSA-1980143
Degradation of the extracellular matrix R-HSA-1474228
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Neutrophil degranulation R-HSA-6798695
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
p75 NTR receptor-mediated signalling R-HSA-193704
Noncanonical activation of NOTCH3 R-HSA-9017802
Regulated proteolysis of p75NTR R-HSA-193692
Death Receptor Signaling R-HSA-73887
Signaling by ERBB4 R-HSA-1236394
Amyloid fiber formation R-HSA-977225
Disease R-HSA-1643685
Innate Immune System R-HSA-168249
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
Metabolism of proteins R-HSA-392499
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH2 R-HSA-1980145
Immune System R-HSA-168256
Signaling by NOTCH1 in Cancer R-HSA-2644603
Axon guidance R-HSA-422475
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Axon guidance R-HSA-422475
NRIF signals cell death from the nucleus R-HSA-205043
Signal Transduction R-HSA-162582
p75 NTR receptor-mediated signalling R-HSA-193704
Degradation of the extracellular matrix R-HSA-1474228
Disease R-HSA-1643685
Neutrophil degranulation R-HSA-6798695
Signaling by ERBB4 R-HSA-1236394
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
Metabolism of proteins R-HSA-392499
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH4 R-HSA-9013694
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH2 R-HSA-1980145
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 R-HSA-1980143
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Extracellular matrix organization R-HSA-1474244
Developmental Biology R-HSA-1266738
Regulated proteolysis of p75NTR R-HSA-193692
p75 NTR receptor-mediated signalling R-HSA-193704
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Noncanonical activation of NOTCH3 R-HSA-9017802
Regulated proteolysis of p75NTR R-HSA-193692
Neutrophil degranulation R-HSA-6798695
Nervous system development R-HSA-9675108
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NRIF signals cell death from the nucleus R-HSA-205043
Death Receptor Signaling R-HSA-73887
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 R-HSA-1980143
Metabolism of proteins R-HSA-392499
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Developmental Biology R-HSA-1266738
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH4 R-HSA-9013694
Nuclear signaling by ERBB4 R-HSA-1251985
Immune System R-HSA-168256
EPH-Ephrin signaling R-HSA-2682334
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH2 R-HSA-1980145
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
Signaling by ERBB4 R-HSA-1236394
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Amyloid fiber formation R-HSA-977225
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Degradation of the extracellular matrix R-HSA-1474228
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 in Cancer R-HSA-2644603
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
Regulated proteolysis of p75NTR R-HSA-193692
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-Ephrin signaling R-HSA-2682334
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by ERBB4 R-HSA-1236394
Metabolism of proteins R-HSA-392499
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH R-HSA-157118
Axon guidance R-HSA-422475
Amyloid fiber formation R-HSA-977225
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH4 R-HSA-9013694
Developmental Biology R-HSA-1266738
Degradation of the extracellular matrix R-HSA-1474228
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neutrophil degranulation R-HSA-6798695
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Noncanonical activation of NOTCH3 R-HSA-9017802
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH3 R-HSA-9012852
Nuclear signaling by ERBB4 R-HSA-1251985
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 R-HSA-1980143
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Innate Immune System R-HSA-168249
Nervous system development R-HSA-9675108
p75 NTR receptor-mediated signalling R-HSA-193704
Death Receptor Signaling R-HSA-73887
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
EPH-Ephrin signaling R-HSA-2682334
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
Signaling by NOTCH R-HSA-157118
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
Degradation of the extracellular matrix R-HSA-1474228
Signaling by NOTCH2 R-HSA-1980145
NRIF signals cell death from the nucleus R-HSA-205043
Amyloid fiber formation R-HSA-977225
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulated proteolysis of p75NTR R-HSA-193692
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH3 R-HSA-9012852
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Extracellular matrix organization R-HSA-1474244
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Degradation of the extracellular matrix R-HSA-1474228
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Immune System R-HSA-168256
p75 NTR receptor-mediated signalling R-HSA-193704
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 in Cancer R-HSA-2644603
Amyloid fiber formation R-HSA-977225
Developmental Biology R-HSA-1266738
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Metabolism of proteins R-HSA-392499
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH2 R-HSA-1980145
Nervous system development R-HSA-9675108
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Noncanonical activation of NOTCH3 R-HSA-9017802
Axon guidance R-HSA-422475
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
NRIF signals cell death from the nucleus R-HSA-205043
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
Degradation of the extracellular matrix R-HSA-1474228
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
p75 NTR receptor-mediated signalling R-HSA-193704
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH3 R-HSA-9012852
Death Receptor Signaling R-HSA-73887
Innate Immune System R-HSA-168249
Noncanonical activation of NOTCH3 R-HSA-9017802
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by ERBB4 R-HSA-1236394
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH4 R-HSA-9013694
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Extracellular matrix organization R-HSA-1474244
Neutrophil degranulation R-HSA-6798695
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Disease R-HSA-1643685
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signal Transduction R-HSA-162582
NRIF signals cell death from the nucleus R-HSA-205043
Amyloid fiber formation R-HSA-977225
Nuclear signaling by ERBB4 R-HSA-1251985
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH2 R-HSA-1980145
Axon guidance R-HSA-422475
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Innate Immune System R-HSA-168249
Metabolism of proteins R-HSA-392499
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NRIF signals cell death from the nucleus R-HSA-205043
Neutrophil degranulation R-HSA-6798695
Degradation of the extracellular matrix R-HSA-1474228
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 R-HSA-1980143
Signaling by ERBB4 R-HSA-1236394
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Disease R-HSA-1643685
Noncanonical activation of NOTCH3 R-HSA-9017802
EPH-ephrin mediated repulsion of cells R-HSA-3928665
p75 NTR receptor-mediated signalling R-HSA-193704
Nervous system development R-HSA-9675108
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
Amyloid fiber formation R-HSA-977225
Nuclear signaling by ERBB4 R-HSA-1251985
Regulated proteolysis of p75NTR R-HSA-193692
Immune System R-HSA-168256
Signaling by NOTCH4 R-HSA-9013694
Extracellular matrix organization R-HSA-1474244
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH4 R-HSA-9013694
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Noncanonical activation of NOTCH3 R-HSA-9017802
Death Receptor Signaling R-HSA-73887
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Amyloid fiber formation R-HSA-977225
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Degradation of the extracellular matrix R-HSA-1474228
p75 NTR receptor-mediated signalling R-HSA-193704
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
Signaling by ERBB4 R-HSA-1236394
Metabolism of proteins R-HSA-392499
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Developmental Biology R-HSA-1266738
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
Neutrophil degranulation R-HSA-6798695
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Nuclear signaling by ERBB4 R-HSA-1251985
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 in Cancer R-HSA-2644603

Expression Atlas ENSG00000162736
LRG display in Ensembl gene LRG_223
NCBI gene (formerly Entrezgene) 23385
GeneCards 17091
HGNC Symbol HGNC:17091
MIM gene 605254
MIM morbid 142690
UniProtKB Gene Name Q92542
WikiGene 23385
Gene: BACE1
Ensembl ID : ENSG00000186318
Description: beta-secretase 1
Gene Synonyms: BACE
4 APIs:
220 Possible Orthologues:

Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225

Expression Atlas ENSG00000186318
NCBI gene (formerly Entrezgene) 23621
GeneCards 933
HGNC Symbol HGNC:933
MIM gene 604252
UniProtKB Gene Name U3KPS1
WikiGene 23621
Gene: APH1B
Ensembl ID : ENSG00000138613
Description: aph-1 homolog B, gamma-secretase subunit
Gene Synonyms: APH-1B,DKFZP564D0372,PSFL
5 APIs:
193 Possible Orthologues:

Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH4 R-HSA-9013694
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Axon guidance R-HSA-422475
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH2 R-HSA-1980145
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NRIF signals cell death from the nucleus R-HSA-205043
Regulated proteolysis of p75NTR R-HSA-193692
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
p75 NTR receptor-mediated signalling R-HSA-193704
Nervous system development R-HSA-9675108
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Nuclear signaling by ERBB4 R-HSA-1251985
Disease R-HSA-1643685
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH1 in Cancer R-HSA-2644603
Nuclear signaling by ERBB4 R-HSA-1251985
Signal Transduction R-HSA-162582
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH4 R-HSA-9013694
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p75 NTR receptor-mediated signalling R-HSA-193704
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Metabolism of proteins R-HSA-392499
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH2 R-HSA-1980145
Regulated proteolysis of p75NTR R-HSA-193692
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 R-HSA-1980143
NRIF signals cell death from the nucleus R-HSA-205043
Noncanonical activation of NOTCH3 R-HSA-9017802
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
Signaling by NOTCH2 R-HSA-1980145
Metabolism of proteins R-HSA-392499
Signaling by ERBB4 R-HSA-1236394
EPH-Ephrin signaling R-HSA-2682334
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Regulated proteolysis of p75NTR R-HSA-193692
Nervous system development R-HSA-9675108
Nuclear signaling by ERBB4 R-HSA-1251985
p75 NTR receptor-mediated signalling R-HSA-193704
NRIF signals cell death from the nucleus R-HSA-205043
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Disease R-HSA-1643685
Signaling by NOTCH1 R-HSA-1980143
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH4 R-HSA-9013694
Death Receptor Signaling R-HSA-73887
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH4 R-HSA-9013694
Regulated proteolysis of p75NTR R-HSA-193692
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Signaling by NOTCH2 R-HSA-1980145
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH3 R-HSA-9012852
Death Receptor Signaling R-HSA-73887
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NRIF signals cell death from the nucleus R-HSA-205043
Developmental Biology R-HSA-1266738
Amyloid fiber formation R-HSA-977225
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by ERBB4 R-HSA-1236394
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Nuclear signaling by ERBB4 R-HSA-1251985
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 R-HSA-1980143
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 R-HSA-1980143
p75 NTR receptor-mediated signalling R-HSA-193704
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Amyloid fiber formation R-HSA-977225
Nervous system development R-HSA-9675108
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nuclear signaling by ERBB4 R-HSA-1251985
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by ERBB4 R-HSA-1236394
EPH-Ephrin signaling R-HSA-2682334
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 in Cancer R-HSA-2644603
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signal Transduction R-HSA-162582
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH3 R-HSA-9012852
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH3 R-HSA-9012852
Nuclear signaling by ERBB4 R-HSA-1251985
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by ERBB4 R-HSA-1236394
Amyloid fiber formation R-HSA-977225
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 R-HSA-1980143
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Nervous system development R-HSA-9675108
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulated proteolysis of p75NTR R-HSA-193692
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH2 R-HSA-1980145
Axon guidance R-HSA-422475
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by ERBB4 R-HSA-1236394
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 in Cancer R-HSA-2644603
Death Receptor Signaling R-HSA-73887
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Metabolism of proteins R-HSA-392499
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH2 R-HSA-1980145
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH R-HSA-157118
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Amyloid fiber formation R-HSA-977225
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH2 R-HSA-1980145
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
Nuclear signaling by ERBB4 R-HSA-1251985
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 in Cancer R-HSA-2644603
Noncanonical activation of NOTCH3 R-HSA-9017802
Metabolism of proteins R-HSA-392499
Axon guidance R-HSA-422475
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Amyloid fiber formation R-HSA-977225
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
Regulated proteolysis of p75NTR R-HSA-193692
Amyloid fiber formation R-HSA-977225
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Regulated proteolysis of p75NTR R-HSA-193692
Noncanonical activation of NOTCH3 R-HSA-9017802
Signal Transduction R-HSA-162582
Nuclear signaling by ERBB4 R-HSA-1251985
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Axon guidance R-HSA-422475
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH3 R-HSA-9012852
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
Metabolism of proteins R-HSA-392499
NRIF signals cell death from the nucleus R-HSA-205043
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Signaling by NOTCH4 R-HSA-9013694
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH2 R-HSA-1980145

Expression Atlas ENSG00000138613
NCBI gene (formerly Entrezgene) 83464
GeneCards 24080
HGNC Symbol HGNC:24080
MIM gene 607630
UniProtKB Gene Name Q8WW43
WikiGene 83464
Gene: REN
Ensembl ID : ENSG00000143839
Description: renin
Gene Synonyms:
2 APIs:
220 Possible Orthologues:

Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736

Expression Atlas ENSG00000143839
NCBI gene (formerly Entrezgene) 5972
GeneCards 9958
HGNC Symbol HGNC:9958
MIM gene 179820
MIM morbid 613092
UniProtKB Gene Name P00797
WikiGene 5972
Gene: APH1A
Ensembl ID : ENSG00000117362
Description: aph-1 homolog A, gamma-secretase subunit
Gene Synonyms: APH-1A,CGI-78
5 APIs:
138 Possible Orthologues:

Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 in Cancer R-HSA-2644603
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH2 R-HSA-1980145
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Signaling by NOTCH R-HSA-157118
Signaling by ERBB4 R-HSA-1236394
Nuclear signaling by ERBB4 R-HSA-1251985
Amyloid fiber formation R-HSA-977225
EPH-Ephrin signaling R-HSA-2682334
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH3 R-HSA-9012852
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Death Receptor Signaling R-HSA-73887
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of proteins R-HSA-392499
Developmental Biology R-HSA-1266738
Signaling by NOTCH2 R-HSA-1980145
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Amyloid fiber formation R-HSA-977225
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 in Cancer R-HSA-2644603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Axon guidance R-HSA-422475
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Signaling by NOTCH1 R-HSA-1980143
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NRIF signals cell death from the nucleus R-HSA-205043
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH3 R-HSA-9012852
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH4 R-HSA-9013694
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
p75 NTR receptor-mediated signalling R-HSA-193704
Death Receptor Signaling R-HSA-73887
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Signaling by ERBB4 R-HSA-1236394
Regulated proteolysis of p75NTR R-HSA-193692
Nuclear signaling by ERBB4 R-HSA-1251985
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH3 R-HSA-9012852
Metabolism of proteins R-HSA-392499
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Signaling by ERBB4 R-HSA-1236394
EPH-Ephrin signaling R-HSA-2682334
Amyloid fiber formation R-HSA-977225
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 R-HSA-1980143
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Regulated proteolysis of p75NTR R-HSA-193692
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH1 in Cancer R-HSA-2644603
EPH-ephrin mediated repulsion of cells R-HSA-3928665
p75 NTR receptor-mediated signalling R-HSA-193704
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Amyloid fiber formation R-HSA-977225
p75 NTR receptor-mediated signalling R-HSA-193704
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
Signaling by NOTCH2 R-HSA-1980145
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 in Cancer R-HSA-2644603
Death Receptor Signaling R-HSA-73887
Developmental Biology R-HSA-1266738
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Regulated proteolysis of p75NTR R-HSA-193692
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Nuclear signaling by ERBB4 R-HSA-1251985
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by ERBB4 R-HSA-1236394
Noncanonical activation of NOTCH3 R-HSA-9017802
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH3 R-HSA-9012852
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NRIF signals cell death from the nucleus R-HSA-205043
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EPH-Ephrin signaling R-HSA-2682334
Metabolism of proteins R-HSA-392499
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Regulated proteolysis of p75NTR R-HSA-193692
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH2 R-HSA-1980145
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Nervous system development R-HSA-9675108
Death Receptor Signaling R-HSA-73887
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by ERBB4 R-HSA-1236394
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH4 R-HSA-9013694
Developmental Biology R-HSA-1266738
Noncanonical activation of NOTCH3 R-HSA-9017802
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by ERBB4 R-HSA-1236394
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH4 R-HSA-9013694
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 R-HSA-1980143
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH3 R-HSA-9012852
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH R-HSA-157118
Axon guidance R-HSA-422475
Signaling by NOTCH2 R-HSA-1980145
Death Receptor Signaling R-HSA-73887
Amyloid fiber formation R-HSA-977225
Nervous system development R-HSA-9675108
Nuclear signaling by ERBB4 R-HSA-1251985
Metabolism of proteins R-HSA-392499
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-Ephrin signaling R-HSA-2682334
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by ERBB4 R-HSA-1236394
Amyloid fiber formation R-HSA-977225
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 R-HSA-1980143
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH3 R-HSA-9012852
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH2 R-HSA-1980145
NRIF signals cell death from the nucleus R-HSA-205043
Signal Transduction R-HSA-162582
Regulated proteolysis of p75NTR R-HSA-193692
Nuclear signaling by ERBB4 R-HSA-1251985
Disease R-HSA-1643685
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Noncanonical activation of NOTCH3 R-HSA-9017802
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Axon guidance R-HSA-422475
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Death Receptor Signaling R-HSA-73887
Metabolism of proteins R-HSA-392499
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH1 in Cancer R-HSA-2644603
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
Signal Transduction R-HSA-162582
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Axon guidance R-HSA-422475
EPH-Ephrin signaling R-HSA-2682334
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Regulated proteolysis of p75NTR R-HSA-193692
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by ERBB4 R-HSA-1236394
Amyloid fiber formation R-HSA-977225
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH2 R-HSA-1980145
Developmental Biology R-HSA-1266738
p75 NTR receptor-mediated signalling R-HSA-193704
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 R-HSA-1980143
Regulated proteolysis of p75NTR R-HSA-193692
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH2 R-HSA-1980145
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
Axon guidance R-HSA-422475
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Metabolism of proteins R-HSA-392499
Signaling by ERBB4 R-HSA-1236394
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Amyloid fiber formation R-HSA-977225
p75 NTR receptor-mediated signalling R-HSA-193704
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH4 R-HSA-9013694
Death Receptor Signaling R-HSA-73887
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH R-HSA-157118
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
EPH-Ephrin signaling R-HSA-2682334
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nervous system development R-HSA-9675108
Nuclear signaling by ERBB4 R-HSA-1251985
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Axon guidance R-HSA-422475
Signaling by NOTCH1 in Cancer R-HSA-2644603
Amyloid fiber formation R-HSA-977225
Developmental Biology R-HSA-1266738
EPH-Ephrin signaling R-HSA-2682334
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by ERBB4 R-HSA-1236394
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NRIF signals cell death from the nucleus R-HSA-205043
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH2 R-HSA-1980145
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
p75 NTR receptor-mediated signalling R-HSA-193704
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 R-HSA-1980143
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Amyloid fiber formation R-HSA-977225
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Nuclear signaling by ERBB4 R-HSA-1251985
p75 NTR receptor-mediated signalling R-HSA-193704
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
EPH-Ephrin signaling R-HSA-2682334
Disease R-HSA-1643685
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH4 R-HSA-9013694
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH2 R-HSA-1980145
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Axon guidance R-HSA-422475
Death Receptor Signaling R-HSA-73887

Expression Atlas ENSG00000117362
NCBI gene (formerly Entrezgene) 51107
GeneCards 29509
HGNC Symbol HGNC:29509
MIM gene 607629
UniProtKB Gene Name Q96BI3
WikiGene 51107
Gene: CFTR
Ensembl ID : ENSG00000001626
Description: CF transmembrane conductance regulator
Gene Synonyms: ABC35,ABCC7,CF,CFTR/MRP,DJ760C5.1,MRP7,TNR-CFTR
8 APIs:
219 Possible Orthologues:

Disease R-HSA-1643685
Chaperone Mediated Autophagy R-HSA-9613829
Autophagy R-HSA-9612973
Ub-specific processing proteases R-HSA-5689880
Transport of small molecules R-HSA-382551
RHO GTPase cycle R-HSA-9012999
Metabolism of proteins R-HSA-392499
RHO GTPases regulate CFTR trafficking R-HSA-5627083
Deubiquitination R-HSA-5688426
Selective autophagy R-HSA-9663891
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
Post-translational protein modification R-HSA-597592
Aggrephagy R-HSA-9646399
Macroautophagy R-HSA-1632852
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
ABC transporter disorders R-HSA-5619084
Clathrin-mediated endocytosis R-HSA-8856828
ABC-family proteins mediated transport R-HSA-382556
Vesicle-mediated transport R-HSA-5653656
Disorders of transmembrane transporters R-HSA-5619115
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Defective CFTR causes cystic fibrosis R-HSA-5678895
RHOQ GTPase cycle R-HSA-9013406
Membrane Trafficking R-HSA-199991
Late endosomal microautophagy R-HSA-9615710
Disease R-HSA-1643685
RHO GTPase Effectors R-HSA-195258
RHOQ GTPase cycle R-HSA-9013406
Macroautophagy R-HSA-1632852
Transport of small molecules R-HSA-382551
Vesicle-mediated transport R-HSA-5653656
ABC transporter disorders R-HSA-5619084
Selective autophagy R-HSA-9663891
ABC-family proteins mediated transport R-HSA-382556
Disorders of transmembrane transporters R-HSA-5619115
RHO GTPases regulate CFTR trafficking R-HSA-5627083
Ub-specific processing proteases R-HSA-5689880
Signaling by Rho GTPases R-HSA-194315
Autophagy R-HSA-9612973
Post-translational protein modification R-HSA-597592
Disease R-HSA-1643685
RHO GTPase cycle R-HSA-9012999
Metabolism of proteins R-HSA-392499
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Clathrin-mediated endocytosis R-HSA-8856828
Chaperone Mediated Autophagy R-HSA-9613829
Deubiquitination R-HSA-5688426
Signal Transduction R-HSA-162582
RHO GTPase Effectors R-HSA-195258
Membrane Trafficking R-HSA-199991
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Defective CFTR causes cystic fibrosis R-HSA-5678895
Aggrephagy R-HSA-9646399
Late endosomal microautophagy R-HSA-9615710
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transport of small molecules R-HSA-382551
Vesicle-mediated transport R-HSA-5653656
Macroautophagy R-HSA-1632852
Autophagy R-HSA-9612973
Post-translational protein modification R-HSA-597592
Clathrin-mediated endocytosis R-HSA-8856828
Late endosomal microautophagy R-HSA-9615710
RHO GTPases regulate CFTR trafficking R-HSA-5627083
Deubiquitination R-HSA-5688426
RHOQ GTPase cycle R-HSA-9013406
RHO GTPase cycle R-HSA-9012999
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
Membrane Trafficking R-HSA-199991
Chaperone Mediated Autophagy R-HSA-9613829
RHO GTPase Effectors R-HSA-195258
Disorders of transmembrane transporters R-HSA-5619115
ABC-family proteins mediated transport R-HSA-382556
Selective autophagy R-HSA-9663891
Ub-specific processing proteases R-HSA-5689880
Aggrephagy R-HSA-9646399
ABC transporter disorders R-HSA-5619084
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Membrane Trafficking R-HSA-199991
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
ABC transporter disorders R-HSA-5619084
Signal Transduction R-HSA-162582
RHO GTPase cycle R-HSA-9012999
Clathrin-mediated endocytosis R-HSA-8856828
Aggrephagy R-HSA-9646399
Defective CFTR causes cystic fibrosis R-HSA-5678895
Macroautophagy R-HSA-1632852
Autophagy R-HSA-9612973
Chaperone Mediated Autophagy R-HSA-9613829
Disorders of transmembrane transporters R-HSA-5619115
RHO GTPase Effectors R-HSA-195258
ABC-family proteins mediated transport R-HSA-382556
Late endosomal microautophagy R-HSA-9615710
Disease R-HSA-1643685
Selective autophagy R-HSA-9663891
RHO GTPases regulate CFTR trafficking R-HSA-5627083
Vesicle-mediated transport R-HSA-5653656
Signaling by Rho GTPases R-HSA-194315
Metabolism of proteins R-HSA-392499
Transport of small molecules R-HSA-382551
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Post-translational protein modification R-HSA-597592
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
RHOQ GTPase cycle R-HSA-9013406
RHO GTPases regulate CFTR trafficking R-HSA-5627083
Membrane Trafficking R-HSA-199991
Signaling by Rho GTPases R-HSA-194315
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Post-translational protein modification R-HSA-597592
Late endosomal microautophagy R-HSA-9615710
Defective CFTR causes cystic fibrosis R-HSA-5678895
Clathrin-mediated endocytosis R-HSA-8856828
Aggrephagy R-HSA-9646399
Disease R-HSA-1643685
Autophagy R-HSA-9612973
Deubiquitination R-HSA-5688426
Macroautophagy R-HSA-1632852
Disorders of transmembrane transporters R-HSA-5619115
Vesicle-mediated transport R-HSA-5653656
RHOQ GTPase cycle R-HSA-9013406
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Transport of small molecules R-HSA-382551
ABC transporter disorders R-HSA-5619084
Ub-specific processing proteases R-HSA-5689880
RHO GTPase Effectors R-HSA-195258
Metabolism of proteins R-HSA-392499
RHO GTPase cycle R-HSA-9012999
Chaperone Mediated Autophagy R-HSA-9613829
Selective autophagy R-HSA-9663891
Signal Transduction R-HSA-162582
ABC-family proteins mediated transport R-HSA-382556
Aggrephagy R-HSA-9646399
Selective autophagy R-HSA-9663891
Signal Transduction R-HSA-162582
RHOQ GTPase cycle R-HSA-9013406
Membrane Trafficking R-HSA-199991
Late endosomal microautophagy R-HSA-9615710
Autophagy R-HSA-9612973
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Vesicle-mediated transport R-HSA-5653656
Macroautophagy R-HSA-1632852
ABC-family proteins mediated transport R-HSA-382556
RHO GTPase cycle R-HSA-9012999
Ub-specific processing proteases R-HSA-5689880
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPases regulate CFTR trafficking R-HSA-5627083
Post-translational protein modification R-HSA-597592
Signaling by Rho GTPases R-HSA-194315
Metabolism of proteins R-HSA-392499
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
ABC transporter disorders R-HSA-5619084
RHO GTPase Effectors R-HSA-195258
Clathrin-mediated endocytosis R-HSA-8856828
Deubiquitination R-HSA-5688426
Disorders of transmembrane transporters R-HSA-5619115
Chaperone Mediated Autophagy R-HSA-9613829
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by Rho GTPases R-HSA-194315
Selective autophagy R-HSA-9663891
Transport of small molecules R-HSA-382551
Chaperone Mediated Autophagy R-HSA-9613829
ABC transporter disorders R-HSA-5619084
RHO GTPase Effectors R-HSA-195258
Late endosomal microautophagy R-HSA-9615710
Disease R-HSA-1643685
Post-translational protein modification R-HSA-597592
Aggrephagy R-HSA-9646399
Membrane Trafficking R-HSA-199991
Signal Transduction R-HSA-162582
Autophagy R-HSA-9612973
Ub-specific processing proteases R-HSA-5689880
Clathrin-mediated endocytosis R-HSA-8856828
Deubiquitination R-HSA-5688426
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Macroautophagy R-HSA-1632852
Vesicle-mediated transport R-HSA-5653656
Disorders of transmembrane transporters R-HSA-5619115
ABC-family proteins mediated transport R-HSA-382556
RHO GTPases regulate CFTR trafficking R-HSA-5627083
Metabolism of proteins R-HSA-392499
RHO GTPase cycle R-HSA-9012999
RHOQ GTPase cycle R-HSA-9013406
RHO GTPase Effectors R-HSA-195258
Chaperone Mediated Autophagy R-HSA-9613829
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Selective autophagy R-HSA-9663891
Clathrin-mediated endocytosis R-HSA-8856828
RHO GTPase cycle R-HSA-9012999
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
Vesicle-mediated transport R-HSA-5653656
Aggrephagy R-HSA-9646399
Macroautophagy R-HSA-1632852
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Post-translational protein modification R-HSA-597592
ABC-family proteins mediated transport R-HSA-382556
Late endosomal microautophagy R-HSA-9615710
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Disorders of transmembrane transporters R-HSA-5619115
Deubiquitination R-HSA-5688426
Signaling by Rho GTPases R-HSA-194315
Autophagy R-HSA-9612973
Membrane Trafficking R-HSA-199991
ABC transporter disorders R-HSA-5619084
Defective CFTR causes cystic fibrosis R-HSA-5678895
RHO GTPases regulate CFTR trafficking R-HSA-5627083
RHOQ GTPase cycle R-HSA-9013406
Aggrephagy R-HSA-9646399
Post-translational protein modification R-HSA-597592
ABC-family proteins mediated transport R-HSA-382556
Membrane Trafficking R-HSA-199991
Signal Transduction R-HSA-162582
RHO GTPase Effectors R-HSA-195258
Clathrin-mediated endocytosis R-HSA-8856828
ABC transporter disorders R-HSA-5619084
Late endosomal microautophagy R-HSA-9615710
Macroautophagy R-HSA-1632852
Ub-specific processing proteases R-HSA-5689880
Vesicle-mediated transport R-HSA-5653656
Disorders of transmembrane transporters R-HSA-5619115
RHO GTPases regulate CFTR trafficking R-HSA-5627083
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
RHOQ GTPase cycle R-HSA-9013406
Autophagy R-HSA-9612973
Transport of small molecules R-HSA-382551
Defective CFTR causes cystic fibrosis R-HSA-5678895
Chaperone Mediated Autophagy R-HSA-9613829
Signaling by Rho GTPases R-HSA-194315
Metabolism of proteins R-HSA-392499
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
RHO GTPase cycle R-HSA-9012999
Selective autophagy R-HSA-9663891
Autophagy R-HSA-9612973
Post-translational protein modification R-HSA-597592
RHOQ GTPase cycle R-HSA-9013406
Deubiquitination R-HSA-5688426
Transport of small molecules R-HSA-382551
Chaperone Mediated Autophagy R-HSA-9613829
RHO GTPase Effectors R-HSA-195258
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Disorders of transmembrane transporters R-HSA-5619115
Signal Transduction R-HSA-162582
Membrane Trafficking R-HSA-199991
ABC-family proteins mediated transport R-HSA-382556
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase cycle R-HSA-9012999
Vesicle-mediated transport R-HSA-5653656
Clathrin-mediated endocytosis R-HSA-8856828
Aggrephagy R-HSA-9646399
Selective autophagy R-HSA-9663891
ABC transporter disorders R-HSA-5619084
Macroautophagy R-HSA-1632852
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Late endosomal microautophagy R-HSA-9615710
RHO GTPases regulate CFTR trafficking R-HSA-5627083
Signaling by Rho GTPases R-HSA-194315

Expression Atlas ENSG00000001626
LRG display in Ensembl gene LRG_663
NCBI gene (formerly Entrezgene) 1080
GeneCards 1884
HGNC Symbol HGNC:1884
MIM gene 602421
MIM morbid 277180
UniProtKB Gene Name P13569
WikiGene 1080
Gene: HCN4
Ensembl ID : ENSG00000138622
Description: hyperpolarization activated cyclic nucleotide gated potassium channel 4
Gene Synonyms:
3 APIs:
288 Possible Orthologues:

HCN channels R-HSA-1296061
Potassium Channels R-HSA-1296071
Neuronal System R-HSA-112316
Neuronal System R-HSA-112316
Potassium Channels R-HSA-1296071
HCN channels R-HSA-1296061
Neuronal System R-HSA-112316
Potassium Channels R-HSA-1296071
HCN channels R-HSA-1296061
Neuronal System R-HSA-112316
HCN channels R-HSA-1296061
Potassium Channels R-HSA-1296071
HCN channels R-HSA-1296061
Neuronal System R-HSA-112316
Potassium Channels R-HSA-1296071
Potassium Channels R-HSA-1296071
HCN channels R-HSA-1296061
Neuronal System R-HSA-112316
HCN channels R-HSA-1296061
Potassium Channels R-HSA-1296071
Neuronal System R-HSA-112316
HCN channels R-HSA-1296061
Neuronal System R-HSA-112316
Potassium Channels R-HSA-1296071
Potassium Channels R-HSA-1296071
HCN channels R-HSA-1296061
Neuronal System R-HSA-112316

Expression Atlas ENSG00000138622
NCBI gene (formerly Entrezgene) 10021
GeneCards 16882
HGNC Symbol HGNC:16882
MIM gene 605206
MIM morbid 619521
UniProtKB Gene Name Q9Y3Q4
WikiGene 10021
Gene: CTSK
Ensembl ID : ENSG00000143387
Description: cathepsin K
Gene Synonyms: CTSO,CTSO2,PKND,PYCD
2 APIs:
246 Possible Orthologues:

Innate Immune System R-HSA-168249
Collagen degradation R-HSA-1442490
RNA Polymerase II Transcription R-HSA-73857
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
MHC class II antigen presentation R-HSA-2132295
Trafficking and processing of endosomal TLR R-HSA-1679131
Generic Transcription Pathway R-HSA-212436
Toll-like Receptor Cascades R-HSA-168898
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of the extracellular matrix R-HSA-1474228
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Collagen degradation R-HSA-1442490
Gene expression (Transcription) R-HSA-74160
Degradation of the extracellular matrix R-HSA-1474228
Toll-like Receptor Cascades R-HSA-168898
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Trafficking and processing of endosomal TLR R-HSA-1679131
Activation of Matrix Metalloproteinases R-HSA-1592389
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
Extracellular matrix organization R-HSA-1474244
MHC class II antigen presentation R-HSA-2132295
Transcriptional regulation by RUNX1 R-HSA-8878171
RNA Polymerase II Transcription R-HSA-73857
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Gene expression (Transcription) R-HSA-74160
Collagen degradation R-HSA-1442490
Activation of Matrix Metalloproteinases R-HSA-1592389
Immune System R-HSA-168256
Trafficking and processing of endosomal TLR R-HSA-1679131
Degradation of the extracellular matrix R-HSA-1474228
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Adaptive Immune System R-HSA-1280218
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX1 R-HSA-8878171
MHC class II antigen presentation R-HSA-2132295
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Immune System R-HSA-168256
Degradation of the extracellular matrix R-HSA-1474228
Trafficking and processing of endosomal TLR R-HSA-1679131
Innate Immune System R-HSA-168249
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
Collagen degradation R-HSA-1442490
Extracellular matrix organization R-HSA-1474244
Adaptive Immune System R-HSA-1280218
Generic Transcription Pathway R-HSA-212436
Toll-like Receptor Cascades R-HSA-168898
MHC class II antigen presentation R-HSA-2132295
Activation of Matrix Metalloproteinases R-HSA-1592389
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Collagen degradation R-HSA-1442490
Adaptive Immune System R-HSA-1280218
Toll-like Receptor Cascades R-HSA-168898
Gene expression (Transcription) R-HSA-74160
Activation of Matrix Metalloproteinases R-HSA-1592389
Immune System R-HSA-168256
Degradation of the extracellular matrix R-HSA-1474228
MHC class II antigen presentation R-HSA-2132295
Trafficking and processing of endosomal TLR R-HSA-1679131
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX1 R-HSA-8878171
Extracellular matrix organization R-HSA-1474244
Generic Transcription Pathway R-HSA-212436
Innate Immune System R-HSA-168249
Collagen degradation R-HSA-1442490
Degradation of the extracellular matrix R-HSA-1474228
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
MHC class II antigen presentation R-HSA-2132295
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Activation of Matrix Metalloproteinases R-HSA-1592389
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
Trafficking and processing of endosomal TLR R-HSA-1679131
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Collagen degradation R-HSA-1442490
Trafficking and processing of endosomal TLR R-HSA-1679131
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Generic Transcription Pathway R-HSA-212436
Activation of Matrix Metalloproteinases R-HSA-1592389
Toll-like Receptor Cascades R-HSA-168898
MHC class II antigen presentation R-HSA-2132295
Transcriptional regulation by RUNX1 R-HSA-8878171
Adaptive Immune System R-HSA-1280218
Extracellular matrix organization R-HSA-1474244
RNA Polymerase II Transcription R-HSA-73857
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Trafficking and processing of endosomal TLR R-HSA-1679131
Degradation of the extracellular matrix R-HSA-1474228
RNA Polymerase II Transcription R-HSA-73857
MHC class II antigen presentation R-HSA-2132295
Adaptive Immune System R-HSA-1280218
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of Matrix Metalloproteinases R-HSA-1592389
Collagen degradation R-HSA-1442490
MHC class II antigen presentation R-HSA-2132295
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
Generic Transcription Pathway R-HSA-212436
Degradation of the extracellular matrix R-HSA-1474228
Activation of Matrix Metalloproteinases R-HSA-1592389
RNA Polymerase II Transcription R-HSA-73857
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Trafficking and processing of endosomal TLR R-HSA-1679131
Collagen degradation R-HSA-1442490
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Innate Immune System R-HSA-168249
Degradation of the extracellular matrix R-HSA-1474228
RNA Polymerase II Transcription R-HSA-73857
Toll-like Receptor Cascades R-HSA-168898
MHC class II antigen presentation R-HSA-2132295
Collagen degradation R-HSA-1442490
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of Matrix Metalloproteinases R-HSA-1592389
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Immune System R-HSA-168256
Extracellular matrix organization R-HSA-1474244
Trafficking and processing of endosomal TLR R-HSA-1679131
Adaptive Immune System R-HSA-1280218

Expression Atlas ENSG00000143387
NCBI gene (formerly Entrezgene) 1513
GeneCards 2536
HGNC Symbol HGNC:2536
MIM gene 601105
MIM morbid 265800
UniProtKB Gene Name Q5QP40
WikiGene 1513