Gene: HTR1A
Ensembl ID : ENSG00000178394
Description: 5-hydroxytryptamine receptor 1A
Gene Synonyms: 5-HT1A,ADRB2RL1,ADRBRL1
26 APIs:
150 Possible Orthologues:

GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Amine ligand-binding receptors R-HSA-375280
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Serotonin receptors R-HSA-390666
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
Serotonin receptors R-HSA-390666
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Amine ligand-binding receptors R-HSA-375280
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Serotonin receptors R-HSA-390666
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Signaling by GPCR R-HSA-372790
Serotonin receptors R-HSA-390666
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Amine ligand-binding receptors R-HSA-375280
GPCR ligand binding R-HSA-500792
Serotonin receptors R-HSA-390666
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Amine ligand-binding receptors R-HSA-375280
GPCR ligand binding R-HSA-500792
Amine ligand-binding receptors R-HSA-375280
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Serotonin receptors R-HSA-390666
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Serotonin receptors R-HSA-390666
Amine ligand-binding receptors R-HSA-375280
Signal Transduction R-HSA-162582
Serotonin receptors R-HSA-390666
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Amine ligand-binding receptors R-HSA-375280
GPCR ligand binding R-HSA-500792
GPCR ligand binding R-HSA-500792
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Serotonin receptors R-HSA-390666
Class A/1 (Rhodopsin-like receptors) R-HSA-373076

Expression Atlas ENSG00000178394
NCBI gene (formerly Entrezgene) 3350
GeneCards 5286
HGNC Symbol HGNC:5286
MIM gene 109760
MIM morbid 614674
UniProtKB Gene Name Q5ZGX3
WikiGene 3350
Gene: ABCC8
Ensembl ID : ENSG00000006071
Description: ATP binding cassette subfamily C member 8
Gene Synonyms: ABC36,HHF1,HI,HRINS,MRP8,PHHI,SUR,SUR1,TNDM2
11 APIs:
245 Possible Orthologues:

Inwardly rectifying K+ channels R-HSA-1296065
Disease R-HSA-1643685
Disorders of transmembrane transporters R-HSA-5619115
Metabolism R-HSA-1430728
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Neuronal System R-HSA-112316
Potassium Channels R-HSA-1296071
Regulation of insulin secretion R-HSA-422356
ATP sensitive Potassium channels R-HSA-1296025
ABC transporter disorders R-HSA-5619084
Integration of energy metabolism R-HSA-163685
Regulation of insulin secretion R-HSA-422356
Integration of energy metabolism R-HSA-163685
Metabolism R-HSA-1430728
ATP sensitive Potassium channels R-HSA-1296025
ABC transporter disorders R-HSA-5619084
Potassium Channels R-HSA-1296071
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Disorders of transmembrane transporters R-HSA-5619115
Disease R-HSA-1643685
Neuronal System R-HSA-112316
Inwardly rectifying K+ channels R-HSA-1296065
Regulation of insulin secretion R-HSA-422356
Disorders of transmembrane transporters R-HSA-5619115
ATP sensitive Potassium channels R-HSA-1296025
Disease R-HSA-1643685
Potassium Channels R-HSA-1296071
Metabolism R-HSA-1430728
Integration of energy metabolism R-HSA-163685
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Inwardly rectifying K+ channels R-HSA-1296065
Neuronal System R-HSA-112316
ABC transporter disorders R-HSA-5619084
Disease R-HSA-1643685
ABC transporter disorders R-HSA-5619084
Inwardly rectifying K+ channels R-HSA-1296065
Neuronal System R-HSA-112316
ATP sensitive Potassium channels R-HSA-1296025
Regulation of insulin secretion R-HSA-422356
Potassium Channels R-HSA-1296071
Disorders of transmembrane transporters R-HSA-5619115
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Integration of energy metabolism R-HSA-163685
Metabolism R-HSA-1430728
ABC transporter disorders R-HSA-5619084
Regulation of insulin secretion R-HSA-422356
ATP sensitive Potassium channels R-HSA-1296025
Neuronal System R-HSA-112316
Potassium Channels R-HSA-1296071
Metabolism R-HSA-1430728
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Disease R-HSA-1643685
Integration of energy metabolism R-HSA-163685
Disorders of transmembrane transporters R-HSA-5619115
Inwardly rectifying K+ channels R-HSA-1296065
Disease R-HSA-1643685
Regulation of insulin secretion R-HSA-422356
Inwardly rectifying K+ channels R-HSA-1296065
ATP sensitive Potassium channels R-HSA-1296025
Integration of energy metabolism R-HSA-163685
Metabolism R-HSA-1430728
ABC transporter disorders R-HSA-5619084
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Neuronal System R-HSA-112316
Disorders of transmembrane transporters R-HSA-5619115
Potassium Channels R-HSA-1296071
ABC transporter disorders R-HSA-5619084
Inwardly rectifying K+ channels R-HSA-1296065
Disorders of transmembrane transporters R-HSA-5619115
Metabolism R-HSA-1430728
Neuronal System R-HSA-112316
Disease R-HSA-1643685
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Regulation of insulin secretion R-HSA-422356
Potassium Channels R-HSA-1296071
Integration of energy metabolism R-HSA-163685
ATP sensitive Potassium channels R-HSA-1296025
Potassium Channels R-HSA-1296071
Regulation of insulin secretion R-HSA-422356
Disorders of transmembrane transporters R-HSA-5619115
ABC transporter disorders R-HSA-5619084
Inwardly rectifying K+ channels R-HSA-1296065
Metabolism R-HSA-1430728
ATP sensitive Potassium channels R-HSA-1296025
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Neuronal System R-HSA-112316
Integration of energy metabolism R-HSA-163685
Disease R-HSA-1643685
ABC transporter disorders R-HSA-5619084
ATP sensitive Potassium channels R-HSA-1296025
Metabolism R-HSA-1430728
Inwardly rectifying K+ channels R-HSA-1296065
Disease R-HSA-1643685
Regulation of insulin secretion R-HSA-422356
Potassium Channels R-HSA-1296071
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Disorders of transmembrane transporters R-HSA-5619115
Neuronal System R-HSA-112316
Integration of energy metabolism R-HSA-163685
Metabolism R-HSA-1430728
Integration of energy metabolism R-HSA-163685
Inwardly rectifying K+ channels R-HSA-1296065
Potassium Channels R-HSA-1296071
Disorders of transmembrane transporters R-HSA-5619115
Regulation of insulin secretion R-HSA-422356
Disease R-HSA-1643685
ABC transporter disorders R-HSA-5619084
Neuronal System R-HSA-112316
ATP sensitive Potassium channels R-HSA-1296025
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177

Expression Atlas ENSG00000006071
LRG display in Ensembl gene LRG_790
NCBI gene (formerly Entrezgene) 6833
GeneCards 59
HGNC Symbol HGNC:59
MIM gene 600509
MIM morbid 618857
UniProtKB Gene Name Q09428
WikiGene 6833
Gene: KCNJ11
Ensembl ID : ENSG00000187486
Description: potassium inwardly rectifying channel subfamily J member 11
Gene Synonyms: BIR,KIR6.2
13 APIs:
190 Possible Orthologues:

ATP sensitive Potassium channels R-HSA-1296025
Ion homeostasis R-HSA-5578775
Neuronal System R-HSA-112316
Cardiac conduction R-HSA-5576891
Metabolism R-HSA-1430728
Ion homeostasis R-HSA-5578775
Integration of energy metabolism R-HSA-163685
Regulation of insulin secretion R-HSA-422356
Muscle contraction R-HSA-397014
Inwardly rectifying K+ channels R-HSA-1296065
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Transport of small molecules R-HSA-382551
ABC-family proteins mediated transport R-HSA-382556
ABC transporter disorders R-HSA-5619084
Potassium Channels R-HSA-1296071
ATP sensitive Potassium channels R-HSA-1296025
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
Disorders of transmembrane transporters R-HSA-5619115
Disease R-HSA-1643685
Regulation of insulin secretion R-HSA-422356
Transport of small molecules R-HSA-382551
Metabolism R-HSA-1430728
Inwardly rectifying K+ channels R-HSA-1296065
Neuronal System R-HSA-112316
ABC transporter disorders R-HSA-5619084
Disease R-HSA-1643685
ABC-family proteins mediated transport R-HSA-382556
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
Integration of energy metabolism R-HSA-163685
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Disorders of transmembrane transporters R-HSA-5619115
Potassium Channels R-HSA-1296071
Cardiac conduction R-HSA-5576891
Transport of small molecules R-HSA-382551
Potassium Channels R-HSA-1296071
Neuronal System R-HSA-112316
Ion homeostasis R-HSA-5578775
ABC-family proteins mediated transport R-HSA-382556
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
Disorders of transmembrane transporters R-HSA-5619115
Integration of energy metabolism R-HSA-163685
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Muscle contraction R-HSA-397014
ATP sensitive Potassium channels R-HSA-1296025
Regulation of insulin secretion R-HSA-422356
Inwardly rectifying K+ channels R-HSA-1296065
ABC transporter disorders R-HSA-5619084
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Ion homeostasis R-HSA-5578775
Inwardly rectifying K+ channels R-HSA-1296065
ABC-family proteins mediated transport R-HSA-382556
Potassium Channels R-HSA-1296071
Integration of energy metabolism R-HSA-163685
Regulation of insulin secretion R-HSA-422356
Muscle contraction R-HSA-397014
Metabolism R-HSA-1430728
Disorders of transmembrane transporters R-HSA-5619115
ABC transporter disorders R-HSA-5619084
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
Cardiac conduction R-HSA-5576891
ATP sensitive Potassium channels R-HSA-1296025
Neuronal System R-HSA-112316
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
ATP sensitive Potassium channels R-HSA-1296025
Disease R-HSA-1643685
ABC transporter disorders R-HSA-5619084
Potassium Channels R-HSA-1296071
Metabolism R-HSA-1430728
Inwardly rectifying K+ channels R-HSA-1296065
Neuronal System R-HSA-112316
Integration of energy metabolism R-HSA-163685
Cardiac conduction R-HSA-5576891
Ion homeostasis R-HSA-5578775
Regulation of insulin secretion R-HSA-422356
Transport of small molecules R-HSA-382551
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Muscle contraction R-HSA-397014
ABC-family proteins mediated transport R-HSA-382556
Disorders of transmembrane transporters R-HSA-5619115
ABC transporter disorders R-HSA-5619084
ABC-family proteins mediated transport R-HSA-382556
Integration of energy metabolism R-HSA-163685
Cardiac conduction R-HSA-5576891
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Ion homeostasis R-HSA-5578775
Regulation of insulin secretion R-HSA-422356
ATP sensitive Potassium channels R-HSA-1296025
Disorders of transmembrane transporters R-HSA-5619115
Neuronal System R-HSA-112316
Muscle contraction R-HSA-397014
Potassium Channels R-HSA-1296071
Transport of small molecules R-HSA-382551
Inwardly rectifying K+ channels R-HSA-1296065
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
Neuronal System R-HSA-112316
Disorders of transmembrane transporters R-HSA-5619115
ATP sensitive Potassium channels R-HSA-1296025
Inwardly rectifying K+ channels R-HSA-1296065
ABC transporter disorders R-HSA-5619084
Muscle contraction R-HSA-397014
Potassium Channels R-HSA-1296071
Metabolism R-HSA-1430728
ABC-family proteins mediated transport R-HSA-382556
Cardiac conduction R-HSA-5576891
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
Ion homeostasis R-HSA-5578775
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
Regulation of insulin secretion R-HSA-422356
Integration of energy metabolism R-HSA-163685
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Regulation of insulin secretion R-HSA-422356
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
Ion homeostasis R-HSA-5578775
Disease R-HSA-1643685
Potassium Channels R-HSA-1296071
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
Muscle contraction R-HSA-397014
ABC transporter disorders R-HSA-5619084
Neuronal System R-HSA-112316
Inwardly rectifying K+ channels R-HSA-1296065
ABC-family proteins mediated transport R-HSA-382556
Integration of energy metabolism R-HSA-163685
ATP sensitive Potassium channels R-HSA-1296025
Disorders of transmembrane transporters R-HSA-5619115
Cardiac conduction R-HSA-5576891
Potassium Channels R-HSA-1296071
Transport of small molecules R-HSA-382551
Neuronal System R-HSA-112316
Inwardly rectifying K+ channels R-HSA-1296065
Metabolism R-HSA-1430728
ABC transporter disorders R-HSA-5619084
Ion homeostasis R-HSA-5578775
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
ATP sensitive Potassium channels R-HSA-1296025
Cardiac conduction R-HSA-5576891
Integration of energy metabolism R-HSA-163685
Muscle contraction R-HSA-397014
Disorders of transmembrane transporters R-HSA-5619115
ABC-family proteins mediated transport R-HSA-382556
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
Disease R-HSA-1643685
Regulation of insulin secretion R-HSA-422356
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
ABC-family proteins mediated transport R-HSA-382556
Potassium Channels R-HSA-1296071
Ion homeostasis R-HSA-5578775
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
Integration of energy metabolism R-HSA-163685
ATP sensitive Potassium channels R-HSA-1296025
Cardiac conduction R-HSA-5576891
Disorders of transmembrane transporters R-HSA-5619115
Muscle contraction R-HSA-397014
Disease R-HSA-1643685
Neuronal System R-HSA-112316
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
ABC transporter disorders R-HSA-5619084
Inwardly rectifying K+ channels R-HSA-1296065
Regulation of insulin secretion R-HSA-422356
Disorders of transmembrane transporters R-HSA-5619115
Muscle contraction R-HSA-397014
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
ABC transporter disorders R-HSA-5619084
Disease R-HSA-1643685
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177
Metabolism R-HSA-1430728
Potassium Channels R-HSA-1296071
ABC-family proteins mediated transport R-HSA-382556
ATP sensitive Potassium channels R-HSA-1296025
Ion homeostasis R-HSA-5578775
Neuronal System R-HSA-112316
Integration of energy metabolism R-HSA-163685
Inwardly rectifying K+ channels R-HSA-1296065
Regulation of insulin secretion R-HSA-422356
Cardiac conduction R-HSA-5576891
Transport of small molecules R-HSA-382551

Expression Atlas ENSG00000187486
NCBI gene (formerly Entrezgene) 3767
GeneCards 6257
HGNC Symbol HGNC:6257
MIM gene 600937
MIM morbid 618856
UniProtKB Gene Name Q14654
WikiGene 3767
Gene: ABCC9
Ensembl ID : ENSG00000069431
Description: ATP binding cassette subfamily C member 9
Gene Synonyms: CMD1O,SUR2
2 APIs:
231 Possible Orthologues:

ATP sensitive Potassium channels R-HSA-1296025
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
Muscle contraction R-HSA-397014
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
Ion homeostasis R-HSA-5578775
Cardiac conduction R-HSA-5576891
ABC transporter disorders R-HSA-5619084
Disease R-HSA-1643685
Potassium Channels R-HSA-1296071
Inwardly rectifying K+ channels R-HSA-1296065
Neuronal System R-HSA-112316
Disorders of transmembrane transporters R-HSA-5619115
Transport of small molecules R-HSA-382551
ATP sensitive Potassium channels R-HSA-1296025
Neuronal System R-HSA-112316
Inwardly rectifying K+ channels R-HSA-1296065
Disorders of transmembrane transporters R-HSA-5619115
ABC transporter disorders R-HSA-5619084
Muscle contraction R-HSA-397014
ABC-family proteins mediated transport R-HSA-382556
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
Ion homeostasis R-HSA-5578775
Disease R-HSA-1643685
Potassium Channels R-HSA-1296071
Cardiac conduction R-HSA-5576891
Ion homeostasis R-HSA-5578775
Muscle contraction R-HSA-397014
Disease R-HSA-1643685
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
Potassium Channels R-HSA-1296071
ABC-family proteins mediated transport R-HSA-382556
Disorders of transmembrane transporters R-HSA-5619115
ATP sensitive Potassium channels R-HSA-1296025
Inwardly rectifying K+ channels R-HSA-1296065
Neuronal System R-HSA-112316
ABC transporter disorders R-HSA-5619084
Transport of small molecules R-HSA-382551
Cardiac conduction R-HSA-5576891
Disease R-HSA-1643685
ABC-family proteins mediated transport R-HSA-382556
ATP sensitive Potassium channels R-HSA-1296025
Inwardly rectifying K+ channels R-HSA-1296065
Muscle contraction R-HSA-397014
Neuronal System R-HSA-112316
Ion homeostasis R-HSA-5578775
Potassium Channels R-HSA-1296071
Transport of small molecules R-HSA-382551
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
ABC transporter disorders R-HSA-5619084
Disorders of transmembrane transporters R-HSA-5619115
Cardiac conduction R-HSA-5576891
Transport of small molecules R-HSA-382551
ABC transporter disorders R-HSA-5619084
Neuronal System R-HSA-112316
Potassium Channels R-HSA-1296071
Disease R-HSA-1643685
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
Muscle contraction R-HSA-397014
Ion homeostasis R-HSA-5578775
ABC-family proteins mediated transport R-HSA-382556
Disorders of transmembrane transporters R-HSA-5619115
Cardiac conduction R-HSA-5576891
ATP sensitive Potassium channels R-HSA-1296025
Inwardly rectifying K+ channels R-HSA-1296065
Disease R-HSA-1643685
Disorders of transmembrane transporters R-HSA-5619115
Potassium Channels R-HSA-1296071
ATP sensitive Potassium channels R-HSA-1296025
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
Transport of small molecules R-HSA-382551
Neuronal System R-HSA-112316
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
ABC transporter disorders R-HSA-5619084
Inwardly rectifying K+ channels R-HSA-1296065
ABC-family proteins mediated transport R-HSA-382556
Ion homeostasis R-HSA-5578775
ATP sensitive Potassium channels R-HSA-1296025
ABC transporter disorders R-HSA-5619084
Cardiac conduction R-HSA-5576891
Potassium Channels R-HSA-1296071
Disorders of transmembrane transporters R-HSA-5619115
Inwardly rectifying K+ channels R-HSA-1296065
Neuronal System R-HSA-112316
Transport of small molecules R-HSA-382551
Ion homeostasis R-HSA-5578775
Disease R-HSA-1643685
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
ABC-family proteins mediated transport R-HSA-382556
Muscle contraction R-HSA-397014
Ion homeostasis R-HSA-5578775
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
Disease R-HSA-1643685
Muscle contraction R-HSA-397014
Transport of small molecules R-HSA-382551
Potassium Channels R-HSA-1296071
Neuronal System R-HSA-112316
ABC-family proteins mediated transport R-HSA-382556
ABC transporter disorders R-HSA-5619084
ATP sensitive Potassium channels R-HSA-1296025
Disorders of transmembrane transporters R-HSA-5619115
Cardiac conduction R-HSA-5576891
Inwardly rectifying K+ channels R-HSA-1296065
Potassium Channels R-HSA-1296071
Inwardly rectifying K+ channels R-HSA-1296065
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
Muscle contraction R-HSA-397014
ABC transporter disorders R-HSA-5619084
Ion homeostasis R-HSA-5578775
Disorders of transmembrane transporters R-HSA-5619115
Cardiac conduction R-HSA-5576891
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
ATP sensitive Potassium channels R-HSA-1296025
Neuronal System R-HSA-112316
ABC-family proteins mediated transport R-HSA-382556
Ion homeostasis R-HSA-5578775
Inwardly rectifying K+ channels R-HSA-1296065
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Neuronal System R-HSA-112316
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420
Transport of small molecules R-HSA-382551
ATP sensitive Potassium channels R-HSA-1296025
ABC-family proteins mediated transport R-HSA-382556
Disorders of transmembrane transporters R-HSA-5619115
Potassium Channels R-HSA-1296071
ABC transporter disorders R-HSA-5619084
Disease R-HSA-1643685

Expression Atlas ENSG00000069431
LRG display in Ensembl gene LRG_377
NCBI gene (formerly Entrezgene) 10060
GeneCards 60
HGNC Symbol HGNC:60
MIM gene 601439
MIM morbid 619719
UniProtKB Gene Name Q8N4N7
WikiGene 10060
Gene: ABCB1
Ensembl ID : ENSG00000085563
Description: ATP binding cassette subfamily B member 1
Gene Synonyms: ABC20,CD243,CLCS,GP170,MDR1,P-170,P-GP,PGY1
2 APIs:
161 Possible Orthologues:

Abacavir ADME R-HSA-2161522
Abacavir transmembrane transport R-HSA-2161517
Drug ADME R-HSA-9748784
Atorvastatin ADME R-HSA-9754706
Prednisone ADME R-HSA-9757110
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
Transport of small molecules R-HSA-382551
Prednisone ADME R-HSA-9757110
Abacavir ADME R-HSA-2161522
ABC-family proteins mediated transport R-HSA-382556
Drug ADME R-HSA-9748784
Abacavir transmembrane transport R-HSA-2161517
Atorvastatin ADME R-HSA-9754706
ABC-family proteins mediated transport R-HSA-382556
Prednisone ADME R-HSA-9757110
Abacavir ADME R-HSA-2161522
Abacavir transmembrane transport R-HSA-2161517
Transport of small molecules R-HSA-382551
Atorvastatin ADME R-HSA-9754706
Drug ADME R-HSA-9748784
Transport of small molecules R-HSA-382551
Atorvastatin ADME R-HSA-9754706
ABC-family proteins mediated transport R-HSA-382556
Drug ADME R-HSA-9748784
Prednisone ADME R-HSA-9757110
Abacavir transmembrane transport R-HSA-2161517
Abacavir ADME R-HSA-2161522
Abacavir transmembrane transport R-HSA-2161517
Prednisone ADME R-HSA-9757110
Abacavir ADME R-HSA-2161522
Transport of small molecules R-HSA-382551
ABC-family proteins mediated transport R-HSA-382556
Atorvastatin ADME R-HSA-9754706
Drug ADME R-HSA-9748784
Abacavir transmembrane transport R-HSA-2161517
Drug ADME R-HSA-9748784
Abacavir ADME R-HSA-2161522
ABC-family proteins mediated transport R-HSA-382556
Atorvastatin ADME R-HSA-9754706
Transport of small molecules R-HSA-382551
Prednisone ADME R-HSA-9757110
Abacavir ADME R-HSA-2161522
Drug ADME R-HSA-9748784
Atorvastatin ADME R-HSA-9754706
ABC-family proteins mediated transport R-HSA-382556
Abacavir transmembrane transport R-HSA-2161517
Prednisone ADME R-HSA-9757110
Transport of small molecules R-HSA-382551
Prednisone ADME R-HSA-9757110
Drug ADME R-HSA-9748784
ABC-family proteins mediated transport R-HSA-382556
Abacavir transmembrane transport R-HSA-2161517
Transport of small molecules R-HSA-382551
Abacavir ADME R-HSA-2161522
Atorvastatin ADME R-HSA-9754706
Atorvastatin ADME R-HSA-9754706
Abacavir ADME R-HSA-2161522
Abacavir transmembrane transport R-HSA-2161517
ABC-family proteins mediated transport R-HSA-382556
Prednisone ADME R-HSA-9757110
Transport of small molecules R-HSA-382551
Drug ADME R-HSA-9748784

Expression Atlas ENSG00000085563
NCBI gene (formerly Entrezgene) 5243
GeneCards 40
HGNC Symbol HGNC:40
MIM gene 171050
MIM morbid 612244
UniProtKB Gene Name P08183
WikiGene 5243
Gene: APH1B
Ensembl ID : ENSG00000138613
Description: aph-1 homolog B, gamma-secretase subunit
Gene Synonyms: APH-1B,DKFZP564D0372,PSFL
5 APIs:
193 Possible Orthologues:

Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH4 R-HSA-9013694
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Axon guidance R-HSA-422475
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH2 R-HSA-1980145
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NRIF signals cell death from the nucleus R-HSA-205043
Regulated proteolysis of p75NTR R-HSA-193692
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
p75 NTR receptor-mediated signalling R-HSA-193704
Nervous system development R-HSA-9675108
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Nuclear signaling by ERBB4 R-HSA-1251985
Disease R-HSA-1643685
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH1 in Cancer R-HSA-2644603
Nuclear signaling by ERBB4 R-HSA-1251985
Signal Transduction R-HSA-162582
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH4 R-HSA-9013694
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p75 NTR receptor-mediated signalling R-HSA-193704
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Metabolism of proteins R-HSA-392499
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH2 R-HSA-1980145
Regulated proteolysis of p75NTR R-HSA-193692
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 R-HSA-1980143
NRIF signals cell death from the nucleus R-HSA-205043
Noncanonical activation of NOTCH3 R-HSA-9017802
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
Signaling by NOTCH2 R-HSA-1980145
Metabolism of proteins R-HSA-392499
Signaling by ERBB4 R-HSA-1236394
EPH-Ephrin signaling R-HSA-2682334
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Regulated proteolysis of p75NTR R-HSA-193692
Nervous system development R-HSA-9675108
Nuclear signaling by ERBB4 R-HSA-1251985
p75 NTR receptor-mediated signalling R-HSA-193704
NRIF signals cell death from the nucleus R-HSA-205043
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Disease R-HSA-1643685
Signaling by NOTCH1 R-HSA-1980143
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH4 R-HSA-9013694
Death Receptor Signaling R-HSA-73887
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH4 R-HSA-9013694
Regulated proteolysis of p75NTR R-HSA-193692
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Signaling by NOTCH2 R-HSA-1980145
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH3 R-HSA-9012852
Death Receptor Signaling R-HSA-73887
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NRIF signals cell death from the nucleus R-HSA-205043
Developmental Biology R-HSA-1266738
Amyloid fiber formation R-HSA-977225
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by ERBB4 R-HSA-1236394
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Nuclear signaling by ERBB4 R-HSA-1251985
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 R-HSA-1980143
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 R-HSA-1980143
p75 NTR receptor-mediated signalling R-HSA-193704
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Amyloid fiber formation R-HSA-977225
Nervous system development R-HSA-9675108
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nuclear signaling by ERBB4 R-HSA-1251985
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by ERBB4 R-HSA-1236394
EPH-Ephrin signaling R-HSA-2682334
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 in Cancer R-HSA-2644603
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signal Transduction R-HSA-162582
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH3 R-HSA-9012852
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH3 R-HSA-9012852
Nuclear signaling by ERBB4 R-HSA-1251985
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by ERBB4 R-HSA-1236394
Amyloid fiber formation R-HSA-977225
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 R-HSA-1980143
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Nervous system development R-HSA-9675108
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulated proteolysis of p75NTR R-HSA-193692
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH2 R-HSA-1980145
Axon guidance R-HSA-422475
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by ERBB4 R-HSA-1236394
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 in Cancer R-HSA-2644603
Death Receptor Signaling R-HSA-73887
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Metabolism of proteins R-HSA-392499
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH2 R-HSA-1980145
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH R-HSA-157118
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Amyloid fiber formation R-HSA-977225
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH2 R-HSA-1980145
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
Nuclear signaling by ERBB4 R-HSA-1251985
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 in Cancer R-HSA-2644603
Noncanonical activation of NOTCH3 R-HSA-9017802
Metabolism of proteins R-HSA-392499
Axon guidance R-HSA-422475
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Amyloid fiber formation R-HSA-977225
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
Regulated proteolysis of p75NTR R-HSA-193692
Amyloid fiber formation R-HSA-977225
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Regulated proteolysis of p75NTR R-HSA-193692
Noncanonical activation of NOTCH3 R-HSA-9017802
Signal Transduction R-HSA-162582
Nuclear signaling by ERBB4 R-HSA-1251985
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Axon guidance R-HSA-422475
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH3 R-HSA-9012852
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
Metabolism of proteins R-HSA-392499
NRIF signals cell death from the nucleus R-HSA-205043
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Signaling by NOTCH4 R-HSA-9013694
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH2 R-HSA-1980145

Expression Atlas ENSG00000138613
NCBI gene (formerly Entrezgene) 83464
GeneCards 24080
HGNC Symbol HGNC:24080
MIM gene 607630
UniProtKB Gene Name Q8WW43
WikiGene 83464
Gene: REN
Ensembl ID : ENSG00000143839
Description: renin
Gene Synonyms:
2 APIs:
220 Possible Orthologues:

Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736

Expression Atlas ENSG00000143839
NCBI gene (formerly Entrezgene) 5972
GeneCards 9958
HGNC Symbol HGNC:9958
MIM gene 179820
MIM morbid 613092
UniProtKB Gene Name P00797
WikiGene 5972
Gene: APH1A
Ensembl ID : ENSG00000117362
Description: aph-1 homolog A, gamma-secretase subunit
Gene Synonyms: APH-1A,CGI-78
5 APIs:
138 Possible Orthologues:

Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 in Cancer R-HSA-2644603
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH2 R-HSA-1980145
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Signaling by NOTCH R-HSA-157118
Signaling by ERBB4 R-HSA-1236394
Nuclear signaling by ERBB4 R-HSA-1251985
Amyloid fiber formation R-HSA-977225
EPH-Ephrin signaling R-HSA-2682334
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH3 R-HSA-9012852
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Death Receptor Signaling R-HSA-73887
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of proteins R-HSA-392499
Developmental Biology R-HSA-1266738
Signaling by NOTCH2 R-HSA-1980145
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Amyloid fiber formation R-HSA-977225
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 in Cancer R-HSA-2644603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Axon guidance R-HSA-422475
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Signaling by NOTCH1 R-HSA-1980143
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NRIF signals cell death from the nucleus R-HSA-205043
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH3 R-HSA-9012852
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH4 R-HSA-9013694
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
p75 NTR receptor-mediated signalling R-HSA-193704
Death Receptor Signaling R-HSA-73887
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Signaling by ERBB4 R-HSA-1236394
Regulated proteolysis of p75NTR R-HSA-193692
Nuclear signaling by ERBB4 R-HSA-1251985
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH3 R-HSA-9012852
Metabolism of proteins R-HSA-392499
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Signaling by ERBB4 R-HSA-1236394
EPH-Ephrin signaling R-HSA-2682334
Amyloid fiber formation R-HSA-977225
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 R-HSA-1980143
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Regulated proteolysis of p75NTR R-HSA-193692
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH1 in Cancer R-HSA-2644603
EPH-ephrin mediated repulsion of cells R-HSA-3928665
p75 NTR receptor-mediated signalling R-HSA-193704
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Amyloid fiber formation R-HSA-977225
p75 NTR receptor-mediated signalling R-HSA-193704
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
Signaling by NOTCH2 R-HSA-1980145
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 in Cancer R-HSA-2644603
Death Receptor Signaling R-HSA-73887
Developmental Biology R-HSA-1266738
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Regulated proteolysis of p75NTR R-HSA-193692
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Nuclear signaling by ERBB4 R-HSA-1251985
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by ERBB4 R-HSA-1236394
Noncanonical activation of NOTCH3 R-HSA-9017802
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH3 R-HSA-9012852
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NRIF signals cell death from the nucleus R-HSA-205043
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EPH-Ephrin signaling R-HSA-2682334
Metabolism of proteins R-HSA-392499
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Regulated proteolysis of p75NTR R-HSA-193692
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH2 R-HSA-1980145
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Nervous system development R-HSA-9675108
Death Receptor Signaling R-HSA-73887
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by ERBB4 R-HSA-1236394
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH4 R-HSA-9013694
Developmental Biology R-HSA-1266738
Noncanonical activation of NOTCH3 R-HSA-9017802
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by ERBB4 R-HSA-1236394
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH4 R-HSA-9013694
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 R-HSA-1980143
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH3 R-HSA-9012852
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH R-HSA-157118
Axon guidance R-HSA-422475
Signaling by NOTCH2 R-HSA-1980145
Death Receptor Signaling R-HSA-73887
Amyloid fiber formation R-HSA-977225
Nervous system development R-HSA-9675108
Nuclear signaling by ERBB4 R-HSA-1251985
Metabolism of proteins R-HSA-392499
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-Ephrin signaling R-HSA-2682334
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by ERBB4 R-HSA-1236394
Amyloid fiber formation R-HSA-977225
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 R-HSA-1980143
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH3 R-HSA-9012852
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH2 R-HSA-1980145
NRIF signals cell death from the nucleus R-HSA-205043
Signal Transduction R-HSA-162582
Regulated proteolysis of p75NTR R-HSA-193692
Nuclear signaling by ERBB4 R-HSA-1251985
Disease R-HSA-1643685
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Noncanonical activation of NOTCH3 R-HSA-9017802
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Axon guidance R-HSA-422475
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Death Receptor Signaling R-HSA-73887
Metabolism of proteins R-HSA-392499
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH1 in Cancer R-HSA-2644603
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
Signal Transduction R-HSA-162582
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Axon guidance R-HSA-422475
EPH-Ephrin signaling R-HSA-2682334
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Regulated proteolysis of p75NTR R-HSA-193692
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by ERBB4 R-HSA-1236394
Amyloid fiber formation R-HSA-977225
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH2 R-HSA-1980145
Developmental Biology R-HSA-1266738
p75 NTR receptor-mediated signalling R-HSA-193704
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 R-HSA-1980143
Regulated proteolysis of p75NTR R-HSA-193692
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH2 R-HSA-1980145
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
Axon guidance R-HSA-422475
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Metabolism of proteins R-HSA-392499
Signaling by ERBB4 R-HSA-1236394
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Amyloid fiber formation R-HSA-977225
p75 NTR receptor-mediated signalling R-HSA-193704
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH4 R-HSA-9013694
Death Receptor Signaling R-HSA-73887
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH R-HSA-157118
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
EPH-Ephrin signaling R-HSA-2682334
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nervous system development R-HSA-9675108
Nuclear signaling by ERBB4 R-HSA-1251985
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Axon guidance R-HSA-422475
Signaling by NOTCH1 in Cancer R-HSA-2644603
Amyloid fiber formation R-HSA-977225
Developmental Biology R-HSA-1266738
EPH-Ephrin signaling R-HSA-2682334
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by ERBB4 R-HSA-1236394
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NRIF signals cell death from the nucleus R-HSA-205043
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH2 R-HSA-1980145
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
p75 NTR receptor-mediated signalling R-HSA-193704
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 R-HSA-1980143
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Amyloid fiber formation R-HSA-977225
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Nuclear signaling by ERBB4 R-HSA-1251985
p75 NTR receptor-mediated signalling R-HSA-193704
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
EPH-Ephrin signaling R-HSA-2682334
Disease R-HSA-1643685
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH4 R-HSA-9013694
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH2 R-HSA-1980145
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Axon guidance R-HSA-422475
Death Receptor Signaling R-HSA-73887

Expression Atlas ENSG00000117362
NCBI gene (formerly Entrezgene) 51107
GeneCards 29509
HGNC Symbol HGNC:29509
MIM gene 607629
UniProtKB Gene Name Q96BI3
WikiGene 51107