Gene: PSMA2
Ensembl ID : ENSG00000106588
Description: proteasome 20S subunit alpha 2
Gene Synonyms: HC3,MU,PMSA2
6 APIs:
231 Possible Orthologues:

Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by NOTCH4 R-HSA-9013694
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Metabolism of proteins R-HSA-392499
Signaling by NOTCH R-HSA-157118
Regulation of Apoptosis R-HSA-169911
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of DVL R-HSA-4641258
Activation of NF-kappaB in B cells R-HSA-1169091
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stimuli R-HSA-8953897
ABC transporter disorders R-HSA-5619084
UCH proteinases R-HSA-5689603
Cellular responses to stress R-HSA-2262752
Regulation of PTEN stability and activity R-HSA-8948751
MAPK6/MAPK4 signaling R-HSA-5687128
Host Interactions of HIV factors R-HSA-162909
RAF/MAP kinase cascade R-HSA-5673001
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of GLI1 by the proteasome R-HSA-5610780
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Downstream TCR signaling R-HSA-202424
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of mitotic cell cycle R-HSA-453276
Innate Immune System R-HSA-168249
Ub-specific processing proteases R-HSA-5689880
Vpu mediated degradation of CD4 R-HSA-180534
G1/S DNA Damage Checkpoints R-HSA-69615
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
DNA Replication R-HSA-69306
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Hedgehog 'off' state R-HSA-5610787
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of GLI2 by the proteasome R-HSA-5610783
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FCERI mediated NF-kB activation R-HSA-2871837
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
Neddylation R-HSA-8951664
Adaptive Immune System R-HSA-1280218
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Synthesis of DNA R-HSA-69239
ER-Phagosome pathway R-HSA-1236974
Disorders of transmembrane transporters R-HSA-5619115
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of polyamines R-HSA-351202
Post-translational protein modification R-HSA-597592
Signaling by WNT R-HSA-195721
PIP3 activates AKT signaling R-HSA-1257604
S Phase R-HSA-69242
Assembly of the pre-replicative complex R-HSA-68867
Gene expression (Transcription) R-HSA-74160
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX3 expression and activity R-HSA-8941858
Neutrophil degranulation R-HSA-6798695
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Anaphase R-HSA-68882
Mitotic G2-G2/M phases R-HSA-453274
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX1 R-HSA-8878171
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
Metabolism of RNA R-HSA-8953854
Transport of small molecules R-HSA-382551
Degradation of AXIN R-HSA-4641257
G2/M Transition R-HSA-69275
Antigen processing-Cross presentation R-HSA-1236975
Programmed Cell Death R-HSA-5357801
PTEN Regulation R-HSA-6807070
Nuclear events mediated by NFE2L2 R-HSA-9759194
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
ABC-family proteins mediated transport R-HSA-382556
G1/S Transition R-HSA-69206
Class I MHC mediated antigen processing & presentation R-HSA-983169
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to hypoxia R-HSA-1234174
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
HIV Infection R-HSA-162906
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Hedgehog R-HSA-5358351
Hh mutants are degraded by ERAD R-HSA-5362768
Nervous system development R-HSA-9675108
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cellular response to chemical stress R-HSA-9711123
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
M Phase R-HSA-68886
Metabolism R-HSA-1430728
G2/M Checkpoints R-HSA-69481
Orc1 removal from chromatin R-HSA-68949
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'on' state R-HSA-5632684
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
DNA Replication Pre-Initiation R-HSA-69002
Stabilization of p53 R-HSA-69541
Axon guidance R-HSA-422475
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of amino acids and derivatives R-HSA-71291
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Deubiquitination R-HSA-5688426
Interleukin-1 family signaling R-HSA-446652
TCR signaling R-HSA-202403
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Separation of Sister Chromatids R-HSA-2467813
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of beta-catenin by the destruction complex R-HSA-195253
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of AXIN R-HSA-4641257
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Beta-catenin independent WNT signaling R-HSA-3858494
Post-translational protein modification R-HSA-597592
Axon guidance R-HSA-422475
Signaling by Hedgehog R-HSA-5358351
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Host Interactions of HIV factors R-HSA-162909
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cell Cycle R-HSA-1640170
TCF dependent signaling in response to WNT R-HSA-201681
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Vpu mediated degradation of CD4 R-HSA-180534
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Asymmetric localization of PCP proteins R-HSA-4608870
Neddylation R-HSA-8951664
p53-Independent DNA Damage Response R-HSA-69610
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of PTEN stability and activity R-HSA-8948751
G1/S DNA Damage Checkpoints R-HSA-69615
TCR signaling R-HSA-202403
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transport of small molecules R-HSA-382551
Metabolism of RNA R-HSA-8953854
ABC-family proteins mediated transport R-HSA-382556
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'off' state R-HSA-5610787
Signaling by WNT R-HSA-195721
Metabolism of amino acids and derivatives R-HSA-71291
Separation of Sister Chromatids R-HSA-2467813
Gene expression (Transcription) R-HSA-74160
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
Cellular response to hypoxia R-HSA-1234174
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle, Mitotic R-HSA-69278
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cytokine Signaling in Immune system R-HSA-1280215
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of beta-catenin by the destruction complex R-HSA-195253
DNA Replication R-HSA-69306
M Phase R-HSA-68886
Nuclear events mediated by NFE2L2 R-HSA-9759194
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of DVL R-HSA-4641258
Activation of NF-kappaB in B cells R-HSA-1169091
Innate Immune System R-HSA-168249
Apoptosis R-HSA-109581
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CLEC7A (Dectin-1) signaling R-HSA-5607764
S Phase R-HSA-69242
UCH proteinases R-HSA-5689603
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
FCERI mediated NF-kB activation R-HSA-2871837
PIP3 activates AKT signaling R-HSA-1257604
Downstream TCR signaling R-HSA-202424
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Synthesis of DNA R-HSA-69239
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
Orc1 removal from chromatin R-HSA-68949
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Metabolism of proteins R-HSA-392499
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Cellular responses to stress R-HSA-2262752
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
ABC transporter disorders R-HSA-5619084
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK family signaling cascades R-HSA-5683057
G2/M Transition R-HSA-69275
MAPK1/MAPK3 signaling R-HSA-5684996
PTEN Regulation R-HSA-6807070
Cellular responses to stimuli R-HSA-8953897
Mitotic Anaphase R-HSA-68882
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog 'on' state R-HSA-5632684
Vif-mediated degradation of APOBEC3G R-HSA-180585
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signal Transduction R-HSA-162582
Degradation of GLI1 by the proteasome R-HSA-5610780
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Interleukin-1 signaling R-HSA-9020702
DNA Replication Pre-Initiation R-HSA-69002
Neutrophil degranulation R-HSA-6798695
Ub-specific processing proteases R-HSA-5689880
Switching of origins to a post-replicative state R-HSA-69052
Nervous system development R-HSA-9675108
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
Cyclin E associated events during G1/S transition R-HSA-69202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
Deubiquitination R-HSA-5688426
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
PCP/CE pathway R-HSA-4086400
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle Checkpoints R-HSA-69620
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of polyamines R-HSA-351202
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by NOTCH R-HSA-157118
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
TCR signaling R-HSA-202403
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Beta-catenin independent WNT signaling R-HSA-3858494
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of RNA R-HSA-8953854
Separation of Sister Chromatids R-HSA-2467813
Adaptive Immune System R-HSA-1280218
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Infectious disease R-HSA-5663205
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Axon guidance R-HSA-422475
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by WNT R-HSA-195721
Metabolism of polyamines R-HSA-351202
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Developmental Biology R-HSA-1266738
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Neddylation R-HSA-8951664
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'off' state R-HSA-5610787
Metabolism of amino acids and derivatives R-HSA-71291
Disorders of transmembrane transporters R-HSA-5619115
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nuclear events mediated by NFE2L2 R-HSA-9759194
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Checkpoints R-HSA-69481
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of proteins R-HSA-392499
Cellular response to chemical stress R-HSA-9711123
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
Downstream TCR signaling R-HSA-202424
Mitotic G2-G2/M phases R-HSA-453274
Mitotic G1 phase and G1/S transition R-HSA-453279
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
HIV Infection R-HSA-162906
Transcriptional regulation by RUNX2 R-HSA-8878166
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of GLI2 by the proteasome R-HSA-5610783
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Synthesis of DNA R-HSA-69239
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transport of small molecules R-HSA-382551
Signaling by NOTCH4 R-HSA-9013694
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PTEN Regulation R-HSA-6807070
Post-translational protein modification R-HSA-597592
Intracellular signaling by second messengers R-HSA-9006925
CLEC7A (Dectin-1) signaling R-HSA-5607764
UCH proteinases R-HSA-5689603
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Defective CFTR causes cystic fibrosis R-HSA-5678895
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ABC-family proteins mediated transport R-HSA-382556
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of Apoptosis R-HSA-169911
S Phase R-HSA-69242
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 signaling R-HSA-9020702
DNA Replication R-HSA-69306
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of AXIN R-HSA-4641257
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
Cell Cycle, Mitotic R-HSA-69278
Assembly of the pre-replicative complex R-HSA-68867
Signal Transduction R-HSA-162582
PCP/CE pathway R-HSA-4086400
Regulation of RAS by GAPs R-HSA-5658442
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Programmed Cell Death R-HSA-5357801
Cellular response to hypoxia R-HSA-1234174
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH R-HSA-157118
ER-Phagosome pathway R-HSA-1236974
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Hedgehog R-HSA-5358351
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK1/MAPK3 signaling R-HSA-5684996
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cell Cycle Checkpoints R-HSA-69620
M Phase R-HSA-68886
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Gene expression (Transcription) R-HSA-74160
Neutrophil degranulation R-HSA-6798695
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
G1/S Transition R-HSA-69206
Class I MHC mediated antigen processing & presentation R-HSA-983169
RNA Polymerase II Transcription R-HSA-73857
MAPK6/MAPK4 signaling R-HSA-5687128
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX3 R-HSA-8878159
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by Interleukins R-HSA-449147
Degradation of DVL R-HSA-4641258
Vpu mediated degradation of CD4 R-HSA-180534
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
DNA Replication R-HSA-69306
Post-translational protein modification R-HSA-597592
TCF dependent signaling in response to WNT R-HSA-201681
Vpu mediated degradation of CD4 R-HSA-180534
ABC-family proteins mediated transport R-HSA-382556
Axon guidance R-HSA-422475
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Programmed Cell Death R-HSA-5357801
Asymmetric localization of PCP proteins R-HSA-4608870
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK6/MAPK4 signaling R-HSA-5687128
Deubiquitination R-HSA-5688426
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Infectious disease R-HSA-5663205
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX2 expression and activity R-HSA-8939902
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
Vif-mediated degradation of APOBEC3G R-HSA-180585
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by WNT R-HSA-195721
p53-Dependent G1 DNA Damage Response R-HSA-69563
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
Metabolism of RNA R-HSA-8953854
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S DNA Damage Checkpoints R-HSA-69615
ABC transporter disorders R-HSA-5619084
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Stabilization of p53 R-HSA-69541
MAPK1/MAPK3 signaling R-HSA-5684996
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Generic Transcription Pathway R-HSA-212436
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of PTEN stability and activity R-HSA-8948751
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular responses to stimuli R-HSA-8953897
Neutrophil degranulation R-HSA-6798695
Metabolism of polyamines R-HSA-351202
Cellular response to chemical stress R-HSA-9711123
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants are degraded by ERAD R-HSA-5362768
Hedgehog 'off' state R-HSA-5610787
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by ROBO receptors R-HSA-376176
Regulation of mitotic cell cycle R-HSA-453276
HIV Infection R-HSA-162906
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog ligand biogenesis R-HSA-5358346
Downstream TCR signaling R-HSA-202424
G1/S Transition R-HSA-69206
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX1 R-HSA-8878171
Cytokine Signaling in Immune system R-HSA-1280215
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog 'on' state R-HSA-5632684
Regulation of Apoptosis R-HSA-169911
Synthesis of DNA R-HSA-69239
TCR signaling R-HSA-202403
Metabolism of amino acids and derivatives R-HSA-71291
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G2-G2/M phases R-HSA-453274
Nervous system development R-HSA-9675108
Assembly of the pre-replicative complex R-HSA-68867
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
UCH proteinases R-HSA-5689603
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
Regulation of expression of SLITs and ROBOs R-HSA-9010553
S Phase R-HSA-69242
Mitotic Anaphase R-HSA-68882
M Phase R-HSA-68886
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Host Interactions of HIV factors R-HSA-162909
p53-Independent DNA Damage Response R-HSA-69610
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Disorders of transmembrane transporters R-HSA-5619115
PCP/CE pathway R-HSA-4086400
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Hedgehog R-HSA-5358351
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of AXIN R-HSA-4641257
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of DVL R-HSA-4641258
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transport of small molecules R-HSA-382551
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Switching of origins to a post-replicative state R-HSA-69052
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Separation of Sister Chromatids R-HSA-2467813
Cell Cycle, Mitotic R-HSA-69278
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 signaling R-HSA-9020702
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G1 phase and G1/S transition R-HSA-453279
FCERI mediated NF-kB activation R-HSA-2871837
Immune System R-HSA-168256
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH4 R-HSA-9013694
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH R-HSA-157118
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Orc1 removal from chromatin R-HSA-68949
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Orc1 removal from chromatin R-HSA-68949
G2/M Checkpoints R-HSA-69481
Separation of Sister Chromatids R-HSA-2467813
C-type lectin receptors (CLRs) R-HSA-5621481
S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Switching of origins to a post-replicative state R-HSA-69052
Synthesis of DNA R-HSA-69239
DNA Replication Pre-Initiation R-HSA-69002
PCP/CE pathway R-HSA-4086400
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Negative regulation of NOTCH4 signaling R-HSA-9604323
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Developmental Biology R-HSA-1266738
Signaling by Hedgehog R-HSA-5358351
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stimuli R-HSA-8953897
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Interleukins R-HSA-449147
Cellular response to chemical stress R-HSA-9711123
HIV Infection R-HSA-162906
TCR signaling R-HSA-202403
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle R-HSA-1640170
Signaling by WNT R-HSA-195721
p53-Dependent G1 DNA Damage Response R-HSA-69563
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Stabilization of p53 R-HSA-69541
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Regulation of Apoptosis R-HSA-169911
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RAS by GAPs R-HSA-5658442
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX2 R-HSA-8878166
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Immune System R-HSA-168256
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vpu mediated degradation of CD4 R-HSA-180534
Vif-mediated degradation of APOBEC3G R-HSA-180585
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic Metaphase and Anaphase R-HSA-2555396
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transport of small molecules R-HSA-382551
Intracellular signaling by second messengers R-HSA-9006925
Nuclear events mediated by NFE2L2 R-HSA-9759194
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
DNA Replication R-HSA-69306
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of polyamines R-HSA-351202
Neutrophil degranulation R-HSA-6798695
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ub-specific processing proteases R-HSA-5689880
Neddylation R-HSA-8951664
Cell Cycle Checkpoints R-HSA-69620
Mitotic Anaphase R-HSA-68882
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Programmed Cell Death R-HSA-5357801
Degradation of DVL R-HSA-4641258
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Post-translational protein modification R-HSA-597592
Regulation of mitotic cell cycle R-HSA-453276
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of PTEN stability and activity R-HSA-8948751
Hedgehog 'on' state R-HSA-5632684
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Independent DNA Damage Response R-HSA-69610
Interleukin-1 signaling R-HSA-9020702
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CLEC7A (Dectin-1) signaling R-HSA-5607764
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX2 expression and activity R-HSA-8939902
M Phase R-HSA-68886
Signaling by NOTCH R-HSA-157118
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of beta-catenin by the destruction complex R-HSA-195253
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G1/S Transition R-HSA-69206
Signaling by ROBO receptors R-HSA-376176
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transcriptional regulation by RUNX1 R-HSA-8878171
ABC-family proteins mediated transport R-HSA-382556
G1/S DNA Damage Checkpoints R-HSA-69615
Infectious disease R-HSA-5663205
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
ABC transporter disorders R-HSA-5619084
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 family signaling R-HSA-446652
Defective CFTR causes cystic fibrosis R-HSA-5678895
UCH proteinases R-HSA-5689603
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'off' state R-HSA-5610787
Activation of NF-kappaB in B cells R-HSA-1169091
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M Transition R-HSA-69275
PTEN Regulation R-HSA-6807070
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of RNA R-HSA-8953854
Degradation of GLI2 by the proteasome R-HSA-5610783
Apoptosis R-HSA-109581
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism R-HSA-1430728
Cellular response to hypoxia R-HSA-1234174
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
HIV Infection R-HSA-162906
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH R-HSA-157118
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PTEN Regulation R-HSA-6807070
Hh mutants are degraded by ERAD R-HSA-5362768
Separation of Sister Chromatids R-HSA-2467813
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'on' state R-HSA-5632684
Switching of origins to a post-replicative state R-HSA-69052
Synthesis of DNA R-HSA-69239
Regulation of RAS by GAPs R-HSA-5658442
Signaling by NOTCH4 R-HSA-9013694
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cyclin E associated events during G1/S transition R-HSA-69202
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants abrogate ligand secretion R-HSA-5387390
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle, Mitotic R-HSA-69278
Signaling by ROBO receptors R-HSA-376176
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
Interleukin-1 signaling R-HSA-9020702
Post-translational protein modification R-HSA-597592
Nervous system development R-HSA-9675108
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular responses to stimuli R-HSA-8953897
G2/M Checkpoints R-HSA-69481
Nuclear events mediated by NFE2L2 R-HSA-9759194
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle R-HSA-1640170
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX3 expression and activity R-HSA-8941858
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX3 R-HSA-8878159
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Defective CFTR causes cystic fibrosis R-HSA-5678895
Stabilization of p53 R-HSA-69541
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by Interleukins R-HSA-449147
ER-Phagosome pathway R-HSA-1236974
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog 'off' state R-HSA-5610787
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
S Phase R-HSA-69242
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Vpu mediated degradation of CD4 R-HSA-180534
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RAF/MAP kinase cascade R-HSA-5673001
TCF dependent signaling in response to WNT R-HSA-201681
Transport of small molecules R-HSA-382551
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Cytokine Signaling in Immune system R-HSA-1280215
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of RNA R-HSA-8953854
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular responses to stress R-HSA-2262752
DNA Replication R-HSA-69306
ABC transporter disorders R-HSA-5619084
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of polyamines R-HSA-351202
Degradation of beta-catenin by the destruction complex R-HSA-195253
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neutrophil degranulation R-HSA-6798695
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
Innate Immune System R-HSA-168249
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle Checkpoints R-HSA-69620
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ub-specific processing proteases R-HSA-5689880
KEAP1-NFE2L2 pathway R-HSA-9755511
Disorders of transmembrane transporters R-HSA-5619115
Vif-mediated degradation of APOBEC3G R-HSA-180585
Deubiquitination R-HSA-5688426
Hedgehog ligand biogenesis R-HSA-5358346
Orc1 removal from chromatin R-HSA-68949
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism R-HSA-1430728
Class I MHC mediated antigen processing & presentation R-HSA-983169
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular response to chemical stress R-HSA-9711123
Degradation of GLI2 by the proteasome R-HSA-5610783
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
ABC-family proteins mediated transport R-HSA-382556
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
M Phase R-HSA-68886
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of DVL R-HSA-4641258
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
TCR signaling R-HSA-202403
Programmed Cell Death R-HSA-5357801
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
Metabolism R-HSA-1430728
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Class I MHC mediated antigen processing & presentation R-HSA-983169
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
HIV Infection R-HSA-162906
Degradation of DVL R-HSA-4641258
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Hedgehog R-HSA-5358351
Immune System R-HSA-168256
Transcriptional regulation by RUNX1 R-HSA-8878171
ABC-family proteins mediated transport R-HSA-382556
Mitotic Anaphase R-HSA-68882
Cell Cycle R-HSA-1640170
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'on' state R-HSA-5632684
Cytokine Signaling in Immune system R-HSA-1280215
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ER-Phagosome pathway R-HSA-1236974
Apoptosis R-HSA-109581
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Switching of origins to a post-replicative state R-HSA-69052
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication Pre-Initiation R-HSA-69002
Neutrophil degranulation R-HSA-6798695
Transport of small molecules R-HSA-382551
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
M Phase R-HSA-68886
Assembly of the pre-replicative complex R-HSA-68867
G1/S Transition R-HSA-69206
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants are degraded by ERAD R-HSA-5362768
Deubiquitination R-HSA-5688426
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
Cyclin E associated events during G1/S transition R-HSA-69202
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ub-specific processing proteases R-HSA-5689880
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by Interleukins R-HSA-449147
Orc1 removal from chromatin R-HSA-68949
G2/M Transition R-HSA-69275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic G1 phase and G1/S transition R-HSA-453279
Intracellular signaling by second messengers R-HSA-9006925
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Separation of Sister Chromatids R-HSA-2467813
CLEC7A (Dectin-1) signaling R-HSA-5607764
PCP/CE pathway R-HSA-4086400
PTEN Regulation R-HSA-6807070
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication R-HSA-69306
G2/M Checkpoints R-HSA-69481
Cellular response to hypoxia R-HSA-1234174
Cell Cycle, Mitotic R-HSA-69278
Vif-mediated degradation of APOBEC3G R-HSA-180585
Disorders of transmembrane transporters R-HSA-5619115
Cellular response to chemical stress R-HSA-9711123
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of Apoptosis R-HSA-169911
p53-Independent DNA Damage Response R-HSA-69610
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of GLI2 by the proteasome R-HSA-5610783
Defective CFTR causes cystic fibrosis R-HSA-5678895
S Phase R-HSA-69242
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of GLI1 by the proteasome R-HSA-5610780
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of AXIN R-HSA-4641257
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by ROBO receptors R-HSA-376176
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RNA Polymerase II Transcription R-HSA-73857
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 signaling R-HSA-9020702
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RAS by GAPs R-HSA-5658442
Signaling by WNT R-HSA-195721
Post-translational protein modification R-HSA-597592
Disease R-HSA-1643685
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle Checkpoints R-HSA-69620
Negative regulation of NOTCH4 signaling R-HSA-9604323
Synthesis of DNA R-HSA-69239
Metabolism of RNA R-HSA-8953854
TCR signaling R-HSA-202403
UCH proteinases R-HSA-5689603
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX3 R-HSA-8878159
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
MAPK1/MAPK3 signaling R-HSA-5684996
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Gene expression (Transcription) R-HSA-74160
Cellular response to hypoxia R-HSA-1234174
Developmental Biology R-HSA-1266738
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of proteins R-HSA-392499
Antigen processing-Cross presentation R-HSA-1236975
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Neutrophil degranulation R-HSA-6798695
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Neddylation R-HSA-8951664
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S DNA Damage Checkpoints R-HSA-69615
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX2 R-HSA-8878166
Ub-specific processing proteases R-HSA-5689880
NIK-->noncanonical NF-kB signaling R-HSA-5676590
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Negative regulation of NOTCH4 signaling R-HSA-9604323
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
S Phase R-HSA-69242
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
ER-Phagosome pathway R-HSA-1236974
Mitotic G2-G2/M phases R-HSA-453274
MAPK6/MAPK4 signaling R-HSA-5687128
G2/M Checkpoints R-HSA-69481
Regulation of mitotic cell cycle R-HSA-453276
Degradation of GLI2 by the proteasome R-HSA-5610783
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
Cell Cycle R-HSA-1640170
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK1/MAPK3 signaling R-HSA-5684996
Transport of small molecules R-HSA-382551
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
Mitotic G1 phase and G1/S transition R-HSA-453279
ABC-family proteins mediated transport R-HSA-382556
Nuclear events mediated by NFE2L2 R-HSA-9759194
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX3 expression and activity R-HSA-8941858
Orc1 removal from chromatin R-HSA-68949
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Class I MHC mediated antigen processing & presentation R-HSA-983169
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
Axon guidance R-HSA-422475
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
UCH proteinases R-HSA-5689603
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin E associated events during G1/S transition R-HSA-69202
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Metabolism of RNA R-HSA-8953854
FCERI mediated NF-kB activation R-HSA-2871837
Nervous system development R-HSA-9675108
Asymmetric localization of PCP proteins R-HSA-4608870
HIV Infection R-HSA-162906
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Synthesis of DNA R-HSA-69239
Activation of NF-kappaB in B cells R-HSA-1169091
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Disorders of transmembrane transporters R-HSA-5619115
Post-translational protein modification R-HSA-597592
Cellular responses to stress R-HSA-2262752
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by WNT R-HSA-195721
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by NOTCH4 R-HSA-9013694
Metabolism R-HSA-1430728
Assembly of the pre-replicative complex R-HSA-68867
Hedgehog 'off' state R-HSA-5610787
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Stabilization of p53 R-HSA-69541
MAPK family signaling cascades R-HSA-5683057
Signaling by Hedgehog R-HSA-5358351
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hedgehog 'on' state R-HSA-5632684
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disease R-HSA-1643685
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Intracellular signaling by second messengers R-HSA-9006925
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Signaling by ROBO receptors R-HSA-376176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 family signaling R-HSA-446652
G1/S Transition R-HSA-69206
Generic Transcription Pathway R-HSA-212436
Metabolism of polyamines R-HSA-351202
Signaling by Interleukins R-HSA-449147
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
Deubiquitination R-HSA-5688426
Interleukin-1 signaling R-HSA-9020702
Separation of Sister Chromatids R-HSA-2467813
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of AXIN R-HSA-4641257
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle Checkpoints R-HSA-69620
Host Interactions of HIV factors R-HSA-162909
Innate Immune System R-HSA-168249
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Innate Immune System R-HSA-168249
Mitotic G1 phase and G1/S transition R-HSA-453279
Infectious disease R-HSA-5663205
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle, Mitotic R-HSA-69278
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Cellular response to chemical stress R-HSA-9711123
Switching of origins to a post-replicative state R-HSA-69052
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Neddylation R-HSA-8951664
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Dependent G1 DNA Damage Response R-HSA-69563
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transport of small molecules R-HSA-382551
Metabolism of polyamines R-HSA-351202
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'off' state R-HSA-5610787
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent DNA Damage Response R-HSA-69610
Disorders of transmembrane transporters R-HSA-5619115
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cell Cycle Checkpoints R-HSA-69620
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Disease R-HSA-1643685
G2/M Transition R-HSA-69275
G2/M Checkpoints R-HSA-69481
Antigen processing-Cross presentation R-HSA-1236975
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Adaptive Immune System R-HSA-1280218
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication R-HSA-69306
Immune System R-HSA-168256
Hedgehog 'on' state R-HSA-5632684
Metabolism R-HSA-1430728
Cellular responses to stress R-HSA-2262752
ABC transporter disorders R-HSA-5619084
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX3 R-HSA-8878159
Vpu mediated degradation of CD4 R-HSA-180534
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX1 R-HSA-8878171
UCH proteinases R-HSA-5689603
Signaling by Interleukins R-HSA-449147
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX2 R-HSA-8878166
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hh mutants are degraded by ERAD R-HSA-5362768
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK family signaling cascades R-HSA-5683057
Cell Cycle R-HSA-1640170
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MAPK1/MAPK3 signaling R-HSA-5684996
Separation of Sister Chromatids R-HSA-2467813
Interleukin-1 signaling R-HSA-9020702
Post-translational protein modification R-HSA-597592
HIV Infection R-HSA-162906
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Neutrophil degranulation R-HSA-6798695
Degradation of GLI1 by the proteasome R-HSA-5610780
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH4 R-HSA-9013694
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Synthesis of DNA R-HSA-69239
Metabolism of proteins R-HSA-392499
Degradation of DVL R-HSA-4641258
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by Hedgehog R-HSA-5358351
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Assembly of the pre-replicative complex R-HSA-68867
Programmed Cell Death R-HSA-5357801
Signal Transduction R-HSA-162582
DNA Replication Pre-Initiation R-HSA-69002
Signaling by NOTCH R-HSA-157118
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of GLI2 by the proteasome R-HSA-5610783
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Intracellular signaling by second messengers R-HSA-9006925
Class I MHC mediated antigen processing & presentation R-HSA-983169
Activation of NF-kappaB in B cells R-HSA-1169091
Ub-specific processing proteases R-HSA-5689880
RNA Polymerase II Transcription R-HSA-73857
Axon guidance R-HSA-422475
G1/S DNA Damage Checkpoints R-HSA-69615
PTEN Regulation R-HSA-6807070
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular responses to stimuli R-HSA-8953897
Negative regulation of NOTCH4 signaling R-HSA-9604323
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
M Phase R-HSA-68886
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mitotic cell cycle R-HSA-453276
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 family signaling R-HSA-446652
Downstream TCR signaling R-HSA-202424
ABC-family proteins mediated transport R-HSA-382556
Regulation of Apoptosis R-HSA-169911
Developmental Biology R-HSA-1266738
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
RAF/MAP kinase cascade R-HSA-5673001
G1/S Transition R-HSA-69206
Degradation of AXIN R-HSA-4641257
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by WNT R-HSA-195721
PCP/CE pathway R-HSA-4086400
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of PTEN stability and activity R-HSA-8948751
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RAS by GAPs R-HSA-5658442
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
Nervous system development R-HSA-9675108
Neddylation R-HSA-8951664
Degradation of DVL R-HSA-4641258
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signaling by Hedgehog R-HSA-5358351
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Disease R-HSA-1643685
Degradation of AXIN R-HSA-4641257
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1 DNA Damage Response R-HSA-69563
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of RNA R-HSA-8953854
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Interleukin-1 signaling R-HSA-9020702
Mitotic G1 phase and G1/S transition R-HSA-453279
Disorders of transmembrane transporters R-HSA-5619115
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Intracellular signaling by second messengers R-HSA-9006925
ABC-family proteins mediated transport R-HSA-382556
Mitotic Anaphase R-HSA-68882
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PTEN Regulation R-HSA-6807070
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Metabolism of polyamines R-HSA-351202
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
Signaling by WNT R-HSA-195721
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Vpu mediated degradation of CD4 R-HSA-180534
Innate Immune System R-HSA-168249
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Defective CFTR causes cystic fibrosis R-HSA-5678895
Axon guidance R-HSA-422475
Hh mutants are degraded by ERAD R-HSA-5362768
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
PCP/CE pathway R-HSA-4086400
Ub-specific processing proteases R-HSA-5689880
G1/S DNA Damage Checkpoints R-HSA-69615
Post-translational protein modification R-HSA-597592
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Assembly of the pre-replicative complex R-HSA-68867
G2/M Checkpoints R-HSA-69481
M Phase R-HSA-68886
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
C-type lectin receptors (CLRs) R-HSA-5621481
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of proteins R-HSA-392499
Adaptive Immune System R-HSA-1280218
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCF dependent signaling in response to WNT R-HSA-201681
Hh mutants abrogate ligand secretion R-HSA-5387390
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism R-HSA-1430728
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream TCR signaling R-HSA-202424
Cellular responses to stress R-HSA-2262752
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle Checkpoints R-HSA-69620
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vif-mediated degradation of APOBEC3G R-HSA-180585
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Asymmetric localization of PCP proteins R-HSA-4608870
Stabilization of p53 R-HSA-69541
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of Apoptosis R-HSA-169911
UCH proteinases R-HSA-5689603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC transporter disorders R-HSA-5619084
Generic Transcription Pathway R-HSA-212436
Apoptosis R-HSA-109581
Neutrophil degranulation R-HSA-6798695
Cellular responses to stimuli R-HSA-8953897
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
HIV Infection R-HSA-162906
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
DNA Replication Pre-Initiation R-HSA-69002
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH4 R-HSA-9013694
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RNA Polymerase II Transcription R-HSA-73857
Transport of small molecules R-HSA-382551
Activation of NF-kappaB in B cells R-HSA-1169091
Orc1 removal from chromatin R-HSA-68949
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by ROBO receptors R-HSA-376176
ER-Phagosome pathway R-HSA-1236974
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Signaling by NOTCH R-HSA-157118
Cellular response to chemical stress R-HSA-9711123
Signal Transduction R-HSA-162582
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog 'on' state R-HSA-5632684
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Switching of origins to a post-replicative state R-HSA-69052
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of amino acids and derivatives R-HSA-71291
Host Interactions of HIV factors R-HSA-162909
HIV Infection R-HSA-162906
PCP/CE pathway R-HSA-4086400
Separation of Sister Chromatids R-HSA-2467813
Neddylation R-HSA-8951664
Signaling by NOTCH4 R-HSA-9013694
Vpu mediated degradation of CD4 R-HSA-180534
RNA Polymerase II Transcription R-HSA-73857
Programmed Cell Death R-HSA-5357801
Regulation of expression of SLITs and ROBOs R-HSA-9010553
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Hedgehog R-HSA-5358351
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
UCH proteinases R-HSA-5689603
Orc1 removal from chromatin R-HSA-68949
Ub-specific processing proteases R-HSA-5689880
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent DNA Damage Response R-HSA-69610
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of AXIN R-HSA-4641257
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Regulation of Apoptosis R-HSA-169911
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Apoptosis R-HSA-109581
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX3 R-HSA-8878159
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of mitotic cell cycle R-HSA-453276
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of DVL R-HSA-4641258
ER-Phagosome pathway R-HSA-1236974
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Synthesis of DNA R-HSA-69239
DNA Replication R-HSA-69306
Regulation of RUNX3 expression and activity R-HSA-8941858
Beta-catenin independent WNT signaling R-HSA-3858494
Signal Transduction R-HSA-162582
Metabolism of polyamines R-HSA-351202
Neutrophil degranulation R-HSA-6798695
Asymmetric localization of PCP proteins R-HSA-4608870
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
Regulation of RAS by GAPs R-HSA-5658442
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH R-HSA-157118
Disorders of transmembrane transporters R-HSA-5619115
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular responses to stimuli R-HSA-8953897
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S DNA Damage Checkpoints R-HSA-69615
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular response to hypoxia R-HSA-1234174
Signaling by WNT R-HSA-195721
Assembly of the pre-replicative complex R-HSA-68867
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
p53-Dependent G1 DNA Damage Response R-HSA-69563
Host Interactions of HIV factors R-HSA-162909
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of NF-kappaB in B cells R-HSA-1169091
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism R-HSA-1430728
G1/S Transition R-HSA-69206
M Phase R-HSA-68886
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of beta-catenin by the destruction complex R-HSA-195253
Switching of origins to a post-replicative state R-HSA-69052
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Class I MHC mediated antigen processing & presentation R-HSA-983169
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX1 R-HSA-8878171
ABC transporter disorders R-HSA-5619084
Cellular responses to stress R-HSA-2262752
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle, Mitotic R-HSA-69278
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of GLI1 by the proteasome R-HSA-5610780
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic Metaphase and Anaphase R-HSA-2555396
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of amino acids and derivatives R-HSA-71291
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of proteins R-HSA-392499
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'on' state R-HSA-5632684
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
Axon guidance R-HSA-422475
G2/M Checkpoints R-HSA-69481
Signaling by Interleukins R-HSA-449147
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle R-HSA-1640170
S Phase R-HSA-69242
MAPK family signaling cascades R-HSA-5683057

Expression Atlas ENSG00000106588
NCBI gene (formerly Entrezgene) 5683
GeneCards 9531
HGNC Symbol HGNC:9531
MIM gene 176842
UniProtKB Gene Name P25787
WikiGene 5683
Gene: PSMB11
Ensembl ID : ENSG00000222028
Description: proteasome subunit beta 11
Gene Synonyms: BETA5T
6 APIs:
228 Possible Orthologues:

Cytokine Signaling in Immune system R-HSA-1280215
TCR signaling R-HSA-202403
Signaling by Interleukins R-HSA-449147
Programmed Cell Death R-HSA-5357801
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G2/M Transition R-HSA-69275
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism R-HSA-1430728
ER-Phagosome pathway R-HSA-1236974
ABC transporter disorders R-HSA-5619084
S Phase R-HSA-69242
Hedgehog 'off' state R-HSA-5610787
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of polyamines R-HSA-351202
Separation of Sister Chromatids R-HSA-2467813
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
p53-Independent DNA Damage Response R-HSA-69610
ABC-family proteins mediated transport R-HSA-382556
Innate Immune System R-HSA-168249
Regulation of mitotic cell cycle R-HSA-453276
Deubiquitination R-HSA-5688426
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic G2-G2/M phases R-HSA-453274
Immune System R-HSA-168256
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stimuli R-HSA-8953897
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX2 R-HSA-8878166
Post-translational protein modification R-HSA-597592
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI2 by the proteasome R-HSA-5610783
RAF/MAP kinase cascade R-HSA-5673001
Degradation of AXIN R-HSA-4641257
Axon guidance R-HSA-422475
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle, Mitotic R-HSA-69278
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Dependent G1 DNA Damage Response R-HSA-69563
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Switching of origins to a post-replicative state R-HSA-69052
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hedgehog 'on' state R-HSA-5632684
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of DVL R-HSA-4641258
Cell Cycle R-HSA-1640170
Mitotic Anaphase R-HSA-68882
Cellular response to chemical stress R-HSA-9711123
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
HIV Infection R-HSA-162906
Hh mutants are degraded by ERAD R-HSA-5362768
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of NF-kappaB in B cells R-HSA-1169091
Ub-specific processing proteases R-HSA-5689880
Synthesis of DNA R-HSA-69239
Transport of small molecules R-HSA-382551
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 signaling R-HSA-9020702
Downstream TCR signaling R-HSA-202424
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
Regulation of Apoptosis R-HSA-169911
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI1 by the proteasome R-HSA-5610780
Antigen processing-Cross presentation R-HSA-1236975
Signaling by WNT R-HSA-195721
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of PTEN stability and activity R-HSA-8948751
Infectious disease R-HSA-5663205
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
C-type lectin receptors (CLRs) R-HSA-5621481
Apoptosis R-HSA-109581
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hh mutants abrogate ligand secretion R-HSA-5387390
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX1 R-HSA-8878171
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of beta-catenin by the destruction complex R-HSA-195253
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Interleukin-1 family signaling R-HSA-446652
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G1/S DNA Damage Checkpoints R-HSA-69615
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular response to hypoxia R-HSA-1234174
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Hedgehog R-HSA-5358351
Separation of Sister Chromatids R-HSA-2467813
Metabolism of RNA R-HSA-8953854
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Metabolism R-HSA-1430728
Programmed Cell Death R-HSA-5357801
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of AXIN R-HSA-4641257
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of polyamines R-HSA-351202
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
Beta-catenin independent WNT signaling R-HSA-3858494
ER-Phagosome pathway R-HSA-1236974
Hedgehog ligand biogenesis R-HSA-5358346
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
ABC-family proteins mediated transport R-HSA-382556
MAPK family signaling cascades R-HSA-5683057
Post-translational protein modification R-HSA-597592
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of Apoptosis R-HSA-169911
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Hedgehog R-HSA-5358351
G2/M Checkpoints R-HSA-69481
Interleukin-1 signaling R-HSA-9020702
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
Mitotic Anaphase R-HSA-68882
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX1 R-HSA-8878171
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stimuli R-HSA-8953897
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI2 by the proteasome R-HSA-5610783
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of amino acids and derivatives R-HSA-71291
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX2 R-HSA-8878166
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Replication R-HSA-69306
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Deubiquitination R-HSA-5688426
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Transport of small molecules R-HSA-382551
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream TCR signaling R-HSA-202424
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of DVL R-HSA-4641258
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mitotic cell cycle R-HSA-453276
Interleukin-1 family signaling R-HSA-446652
Regulation of RAS by GAPs R-HSA-5658442
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RNA Polymerase II Transcription R-HSA-73857
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Axon guidance R-HSA-422475
PIP3 activates AKT signaling R-HSA-1257604
Activation of NF-kappaB in B cells R-HSA-1169091
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic Metaphase and Anaphase R-HSA-2555396
Class I MHC mediated antigen processing & presentation R-HSA-983169
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of proteins R-HSA-392499
Hh mutants are degraded by ERAD R-HSA-5362768
MAPK6/MAPK4 signaling R-HSA-5687128
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Interleukins R-HSA-449147
PCP/CE pathway R-HSA-4086400
Immune System R-HSA-168256
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
ABC transporter disorders R-HSA-5619084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Intracellular signaling by second messengers R-HSA-9006925
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hedgehog 'on' state R-HSA-5632684
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular response to hypoxia R-HSA-1234174
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle Checkpoints R-HSA-69620
NIK-->noncanonical NF-kB signaling R-HSA-5676590
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic G2-G2/M phases R-HSA-453274
Immune System R-HSA-168256
Hh mutants abrogate ligand secretion R-HSA-5387390
ABC-family proteins mediated transport R-HSA-382556
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Axon guidance R-HSA-422475
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
Metabolism R-HSA-1430728
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RAS by GAPs R-HSA-5658442
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'off' state R-HSA-5610787
Hh mutants are degraded by ERAD R-HSA-5362768
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CLEC7A (Dectin-1) signaling R-HSA-5607764
Intracellular signaling by second messengers R-HSA-9006925
Separation of Sister Chromatids R-HSA-2467813
Neddylation R-HSA-8951664
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Interleukins R-HSA-449147
Stabilization of p53 R-HSA-69541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular responses to stress R-HSA-2262752
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to hypoxia R-HSA-1234174
Degradation of GLI1 by the proteasome R-HSA-5610780
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of NF-kappaB in B cells R-HSA-1169091
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Gene expression (Transcription) R-HSA-74160
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Vif-mediated degradation of APOBEC3G R-HSA-180585
Nervous system development R-HSA-9675108
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
S Phase R-HSA-69242
Mitotic Metaphase and Anaphase R-HSA-2555396
Post-translational protein modification R-HSA-597592
HIV Infection R-HSA-162906
Apoptosis R-HSA-109581
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Deubiquitination R-HSA-5688426
Vpu mediated degradation of CD4 R-HSA-180534
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 signaling R-HSA-9020702
Developmental Biology R-HSA-1266738
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Innate Immune System R-HSA-168249
Hedgehog ligand biogenesis R-HSA-5358346
Switching of origins to a post-replicative state R-HSA-69052
G2/M Checkpoints R-HSA-69481
Programmed Cell Death R-HSA-5357801
Cellular responses to stimuli R-HSA-8953897
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PIP3 activates AKT signaling R-HSA-1257604
FCERI mediated NF-kB activation R-HSA-2871837
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of mitotic cell cycle R-HSA-453276
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
M Phase R-HSA-68886
Interleukin-1 family signaling R-HSA-446652
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disorders of transmembrane transporters R-HSA-5619115
Host Interactions of HIV factors R-HSA-162909
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by WNT R-HSA-195721
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent DNA Damage Response R-HSA-69610
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog 'on' state R-HSA-5632684
Metabolism of proteins R-HSA-392499
Cellular response to chemical stress R-HSA-9711123
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by ROBO receptors R-HSA-376176
Orc1 removal from chromatin R-HSA-68949
ABC transporter disorders R-HSA-5619084
Regulation of RUNX2 expression and activity R-HSA-8939902
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
RNA Polymerase II Transcription R-HSA-73857
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Infectious disease R-HSA-5663205
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
DNA Replication R-HSA-69306
Synthesis of DNA R-HSA-69239
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
UCH proteinases R-HSA-5689603
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK family signaling cascades R-HSA-5683057
PTEN Regulation R-HSA-6807070
Cell Cycle R-HSA-1640170
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of polyamines R-HSA-351202
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
Mitotic Anaphase R-HSA-68882
Degradation of DVL R-HSA-4641258
Transcriptional regulation by RUNX2 R-HSA-8878166
Disease R-HSA-1643685
PCP/CE pathway R-HSA-4086400
G2/M Transition R-HSA-69275
Innate Immune System R-HSA-168249
G2/M Checkpoints R-HSA-69481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Hh mutants are degraded by ERAD R-HSA-5362768
G1/S DNA Damage Checkpoints R-HSA-69615
Neddylation R-HSA-8951664
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Defective CFTR causes cystic fibrosis R-HSA-5678895
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
G2/M Transition R-HSA-69275
Cellular response to hypoxia R-HSA-1234174
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of amino acids and derivatives R-HSA-71291
Immune System R-HSA-168256
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
ABC transporter disorders R-HSA-5619084
Hedgehog 'off' state R-HSA-5610787
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
Switching of origins to a post-replicative state R-HSA-69052
Ub-specific processing proteases R-HSA-5689880
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular response to chemical stress R-HSA-9711123
Signaling by Hedgehog R-HSA-5358351
Interleukin-1 family signaling R-HSA-446652
Cell Cycle, Mitotic R-HSA-69278
Degradation of AXIN R-HSA-4641257
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of expression of SLITs and ROBOs R-HSA-9010553
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Adaptive Immune System R-HSA-1280218
Signaling by Interleukins R-HSA-449147
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by WNT R-HSA-195721
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Separation of Sister Chromatids R-HSA-2467813
Orc1 removal from chromatin R-HSA-68949
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by ROBO receptors R-HSA-376176
Regulation of RUNX2 expression and activity R-HSA-8939902
Disease R-HSA-1643685
Metabolism of polyamines R-HSA-351202
Mitotic G2-G2/M phases R-HSA-453274
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
DNA Replication R-HSA-69306
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
PCP/CE pathway R-HSA-4086400
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent DNA Damage Response R-HSA-69610
ABC-family proteins mediated transport R-HSA-382556
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
HIV Infection R-HSA-162906
Apoptosis R-HSA-109581
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK family signaling cascades R-HSA-5683057
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Vif-mediated degradation of APOBEC3G R-HSA-180585
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transport of small molecules R-HSA-382551
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI2 by the proteasome R-HSA-5610783
CLEC7A (Dectin-1) signaling R-HSA-5607764
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of Apoptosis R-HSA-169911
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle R-HSA-1640170
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Beta-catenin independent WNT signaling R-HSA-3858494
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cytokine Signaling in Immune system R-HSA-1280215
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stimuli R-HSA-8953897
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Synthesis of DNA R-HSA-69239
Axon guidance R-HSA-422475
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Programmed Cell Death R-HSA-5357801
Stabilization of p53 R-HSA-69541
UCH proteinases R-HSA-5689603
Class I MHC mediated antigen processing & presentation R-HSA-983169
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX1 R-HSA-8878171
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular responses to stress R-HSA-2262752
Synthesis of DNA R-HSA-69239
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
MAPK6/MAPK4 signaling R-HSA-5687128
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'off' state R-HSA-5610787
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Defective CFTR causes cystic fibrosis R-HSA-5678895
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
TCR signaling R-HSA-202403
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of polyamines R-HSA-351202
Signaling by ROBO receptors R-HSA-376176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Immune System R-HSA-168256
Signaling by Hedgehog R-HSA-5358351
RAF/MAP kinase cascade R-HSA-5673001
Post-translational protein modification R-HSA-597592
Metabolism of RNA R-HSA-8953854
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Disease R-HSA-1643685
Degradation of DVL R-HSA-4641258
Adaptive Immune System R-HSA-1280218
Cell Cycle, Mitotic R-HSA-69278
Signaling by WNT R-HSA-195721
Metabolism of amino acids and derivatives R-HSA-71291
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
Apoptosis R-HSA-109581
ER-Phagosome pathway R-HSA-1236974
KEAP1-NFE2L2 pathway R-HSA-9755511
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI2 by the proteasome R-HSA-5610783
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
UCH proteinases R-HSA-5689603
S Phase R-HSA-69242
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Deubiquitination R-HSA-5688426
CLEC7A (Dectin-1) signaling R-HSA-5607764
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Separation of Sister Chromatids R-HSA-2467813
Transport of small molecules R-HSA-382551
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Host Interactions of HIV factors R-HSA-162909
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PCP/CE pathway R-HSA-4086400
Downstream TCR signaling R-HSA-202424
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
Interleukin-1 signaling R-HSA-9020702
Hh mutants abrogate ligand secretion R-HSA-5387390
TCF dependent signaling in response to WNT R-HSA-201681
Infectious disease R-HSA-5663205
Degradation of AXIN R-HSA-4641257
ABC-family proteins mediated transport R-HSA-382556
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Anaphase R-HSA-68882
ABC transporter disorders R-HSA-5619084
Orc1 removal from chromatin R-HSA-68949
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
PTEN Regulation R-HSA-6807070
Hedgehog 'on' state R-HSA-5632684
Innate Immune System R-HSA-168249
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Replication R-HSA-69306
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic Metaphase and Anaphase R-HSA-2555396
Neddylation R-HSA-8951664
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to hypoxia R-HSA-1234174
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic G2-G2/M phases R-HSA-453274
Axon guidance R-HSA-422475
Regulation of Apoptosis R-HSA-169911
Programmed Cell Death R-HSA-5357801
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Stabilization of p53 R-HSA-69541
C-type lectin receptors (CLRs) R-HSA-5621481
HIV Infection R-HSA-162906
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
Metabolism of amino acids and derivatives R-HSA-71291
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Ub-specific processing proteases R-HSA-5689880
ABC-family proteins mediated transport R-HSA-382556
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
Downstream TCR signaling R-HSA-202424
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vif-mediated degradation of APOBEC3G R-HSA-180585
CLEC7A (Dectin-1) signaling R-HSA-5607764
ER-Phagosome pathway R-HSA-1236974
Cell Cycle R-HSA-1640170
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle, Mitotic R-HSA-69278
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Infectious disease R-HSA-5663205
Asymmetric localization of PCP proteins R-HSA-4608870
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of RAS by GAPs R-HSA-5658442
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Orc1 removal from chromatin R-HSA-68949
Metabolism R-HSA-1430728
p53-Dependent G1 DNA Damage Response R-HSA-69563
Programmed Cell Death R-HSA-5357801
RAF/MAP kinase cascade R-HSA-5673001
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
Regulation of PTEN stability and activity R-HSA-8948751
Host Interactions of HIV factors R-HSA-162909
C-type lectin receptors (CLRs) R-HSA-5621481
Signal Transduction R-HSA-162582
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 signaling R-HSA-9020702
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI1 by the proteasome R-HSA-5610780
UCH proteinases R-HSA-5689603
Gene expression (Transcription) R-HSA-74160
Hedgehog ligand biogenesis R-HSA-5358346
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of RNA R-HSA-8953854
Degradation of DVL R-HSA-4641258
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of polyamines R-HSA-351202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'on' state R-HSA-5632684
Intracellular signaling by second messengers R-HSA-9006925
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Transport of small molecules R-HSA-382551
Regulation of RUNX2 expression and activity R-HSA-8939902
Post-translational protein modification R-HSA-597592
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TCR signaling R-HSA-202403
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic G2-G2/M phases R-HSA-453274
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Immune System R-HSA-168256
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PCP/CE pathway R-HSA-4086400
Degradation of GLI2 by the proteasome R-HSA-5610783
Apoptosis R-HSA-109581
Neddylation R-HSA-8951664
PTEN Regulation R-HSA-6807070
Vpu mediated degradation of CD4 R-HSA-180534
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Interleukins R-HSA-449147
Beta-catenin independent WNT signaling R-HSA-3858494
Hh mutants abrogate ligand secretion R-HSA-5387390
Adaptive Immune System R-HSA-1280218
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
Disease R-HSA-1643685
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Switching of origins to a post-replicative state R-HSA-69052
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Stabilization of p53 R-HSA-69541
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of AXIN R-HSA-4641257
Separation of Sister Chromatids R-HSA-2467813
Nervous system development R-HSA-9675108
Interleukin-1 family signaling R-HSA-446652
M Phase R-HSA-68886
Signaling by ROBO receptors R-HSA-376176
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ABC transporter disorders R-HSA-5619084
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by Hedgehog R-HSA-5358351
Synthesis of DNA R-HSA-69239
Cellular response to chemical stress R-HSA-9711123
Regulation of Apoptosis R-HSA-169911
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Innate Immune System R-HSA-168249
Degradation of beta-catenin by the destruction complex R-HSA-195253
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Anaphase R-HSA-68882
Antigen processing-Cross presentation R-HSA-1236975
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle Checkpoints R-HSA-69620
Cellular response to hypoxia R-HSA-1234174
Deubiquitination R-HSA-5688426
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hedgehog 'off' state R-HSA-5610787
Neddylation R-HSA-8951664
KEAP1-NFE2L2 pathway R-HSA-9755511
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Antigen processing-Cross presentation R-HSA-1236975
G2/M Transition R-HSA-69275
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Anaphase R-HSA-68882
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK family signaling cascades R-HSA-5683057
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
Hh mutants abrogate ligand secretion R-HSA-5387390
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
HIV Infection R-HSA-162906
Hedgehog ligand biogenesis R-HSA-5358346
Hedgehog 'off' state R-HSA-5610787
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 family signaling R-HSA-446652
FCERI mediated NF-kB activation R-HSA-2871837
ER-Phagosome pathway R-HSA-1236974
Regulation of mitotic cell cycle R-HSA-453276
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
UCH proteinases R-HSA-5689603
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Separation of Sister Chromatids R-HSA-2467813
Host Interactions of HIV factors R-HSA-162909
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Disorders of transmembrane transporters R-HSA-5619115
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Hedgehog R-HSA-5358351
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of RUNX2 expression and activity R-HSA-8939902
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transport of small molecules R-HSA-382551
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
RNA Polymerase II Transcription R-HSA-73857
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
Degradation of AXIN R-HSA-4641257
p53-Independent DNA Damage Response R-HSA-69610
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by Interleukins R-HSA-449147
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular responses to stimuli R-HSA-8953897
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Gene expression (Transcription) R-HSA-74160
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism R-HSA-1430728
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Stabilization of p53 R-HSA-69541
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI2 by the proteasome R-HSA-5610783
DNA Replication R-HSA-69306
Mitotic Metaphase and Anaphase R-HSA-2555396
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vif-mediated degradation of APOBEC3G R-HSA-180585
S Phase R-HSA-69242
Apoptosis R-HSA-109581
Cellular response to chemical stress R-HSA-9711123
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle Checkpoints R-HSA-69620
Signal Transduction R-HSA-162582
Hedgehog 'on' state R-HSA-5632684
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of Apoptosis R-HSA-169911
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Programmed Cell Death R-HSA-5357801
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX1 R-HSA-8878171
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of RNA R-HSA-8953854
Cellular response to hypoxia R-HSA-1234174
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
NIK-->noncanonical NF-kB signaling R-HSA-5676590
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Synthesis of DNA R-HSA-69239
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nervous system development R-HSA-9675108
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
RAF/MAP kinase cascade R-HSA-5673001
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cytokine Signaling in Immune system R-HSA-1280215
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Cellular responses to stimuli R-HSA-8953897
MAPK family signaling cascades R-HSA-5683057
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of GLI1 by the proteasome R-HSA-5610780
Degradation of GLI2 by the proteasome R-HSA-5610783
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Immune System R-HSA-168256
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Metaphase and Anaphase R-HSA-2555396
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Transition R-HSA-69275
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Intracellular signaling by second messengers R-HSA-9006925
G1/S DNA Damage Checkpoints R-HSA-69615
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
PIP3 activates AKT signaling R-HSA-1257604
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of amino acids and derivatives R-HSA-71291
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
HIV Infection R-HSA-162906
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
Stabilization of p53 R-HSA-69541
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by Interleukins R-HSA-449147
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle R-HSA-1640170
Signaling by ROBO receptors R-HSA-376176
Signaling by WNT R-HSA-195721
MAPK6/MAPK4 signaling R-HSA-5687128
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transport of small molecules R-HSA-382551
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of proteins R-HSA-392499
Generic Transcription Pathway R-HSA-212436
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'on' state R-HSA-5632684
Deubiquitination R-HSA-5688426
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Post-translational protein modification R-HSA-597592
TCR signaling R-HSA-202403
Developmental Biology R-HSA-1266738
Cellular response to hypoxia R-HSA-1234174
Mitotic Anaphase R-HSA-68882
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of AXIN R-HSA-4641257
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent DNA Damage Response R-HSA-69610
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ub-specific processing proteases R-HSA-5689880
Regulation of mitotic cell cycle R-HSA-453276
Separation of Sister Chromatids R-HSA-2467813
Interleukin-1 signaling R-HSA-9020702
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Disease R-HSA-1643685
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK1/MAPK3 signaling R-HSA-5684996
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of DVL R-HSA-4641258
Metabolism R-HSA-1430728
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Interleukin-1 family signaling R-HSA-446652
Hedgehog 'off' state R-HSA-5610787
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX1 R-HSA-8878171
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular responses to stress R-HSA-2262752
Cell Cycle Checkpoints R-HSA-69620
DNA Replication R-HSA-69306
PCP/CE pathway R-HSA-4086400
Gene expression (Transcription) R-HSA-74160
Apoptosis R-HSA-109581
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX2 R-HSA-8878166
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Axon guidance R-HSA-422475
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hh mutants abrogate ligand secretion R-HSA-5387390
Programmed Cell Death R-HSA-5357801
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Synthesis of DNA R-HSA-69239
ABC transporter disorders R-HSA-5619084
C-type lectin receptors (CLRs) R-HSA-5621481
Orc1 removal from chromatin R-HSA-68949
Regulation of Apoptosis R-HSA-169911
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Switching of origins to a post-replicative state R-HSA-69052
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
G2/M Checkpoints R-HSA-69481
G2/M Transition R-HSA-69275
Signaling by WNT R-HSA-195721
Metabolism of proteins R-HSA-392499
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
Switching of origins to a post-replicative state R-HSA-69052
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
Regulation of Apoptosis R-HSA-169911
Defective CFTR causes cystic fibrosis R-HSA-5678895
UCH proteinases R-HSA-5689603
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Adaptive Immune System R-HSA-1280218
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Stabilization of p53 R-HSA-69541
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Regulation of RAS by GAPs R-HSA-5658442
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of mitotic cell cycle R-HSA-453276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TCF dependent signaling in response to WNT R-HSA-201681
Gene expression (Transcription) R-HSA-74160
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog 'on' state R-HSA-5632684
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Interleukins R-HSA-449147
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nervous system development R-HSA-9675108
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Apoptosis R-HSA-109581
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI2 by the proteasome R-HSA-5610783
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Post-translational protein modification R-HSA-597592
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream TCR signaling R-HSA-202424
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Checkpoints R-HSA-69481
Metabolism R-HSA-1430728
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Class I MHC mediated antigen processing & presentation R-HSA-983169
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
Programmed Cell Death R-HSA-5357801
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S DNA Damage Checkpoints R-HSA-69615
Vpu mediated degradation of CD4 R-HSA-180534
Cellular responses to stimuli R-HSA-8953897
ER-Phagosome pathway R-HSA-1236974
Cell Cycle, Mitotic R-HSA-69278
RNA Polymerase II Transcription R-HSA-73857
Disorders of transmembrane transporters R-HSA-5619115
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
Regulation of RUNX2 expression and activity R-HSA-8939902
CLEC7A (Dectin-1) signaling R-HSA-5607764
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by Hedgehog R-HSA-5358351
Hh mutants abrogate ligand secretion R-HSA-5387390
M Phase R-HSA-68886
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PCP/CE pathway R-HSA-4086400
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell Cycle R-HSA-1640170
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
Synthesis of DNA R-HSA-69239
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
ABC-family proteins mediated transport R-HSA-382556
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
Degradation of DVL R-HSA-4641258
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
C-type lectin receptors (CLRs) R-HSA-5621481
S Phase R-HSA-69242
Orc1 removal from chromatin R-HSA-68949
Signal Transduction R-HSA-162582
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX1 R-HSA-8878171
Axon guidance R-HSA-422475
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hedgehog ligand biogenesis R-HSA-5358346
Cellular response to chemical stress R-HSA-9711123
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to hypoxia R-HSA-1234174
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by ROBO receptors R-HSA-376176
Mitotic Metaphase and Anaphase R-HSA-2555396
Interleukin-1 family signaling R-HSA-446652
Metabolism of RNA R-HSA-8953854
TCR signaling R-HSA-202403
Developmental Biology R-HSA-1266738
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
HIV Infection R-HSA-162906
PTEN Regulation R-HSA-6807070
DNA Replication R-HSA-69306
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of NF-kappaB in B cells R-HSA-1169091
Hedgehog 'off' state R-HSA-5610787
Generic Transcription Pathway R-HSA-212436
Hh mutants are degraded by ERAD R-HSA-5362768

Expression Atlas ENSG00000222028
NCBI gene (formerly Entrezgene) 122706
GeneCards 31963
HGNC Symbol HGNC:31963
MIM gene 611137
UniProtKB Gene Name A5LHX3
WikiGene 122706
Gene: MMP7
Ensembl ID : ENSG00000137673
Description: matrix metallopeptidase 7
Gene Synonyms: MPSL1,PUMP-1
4 APIs:
163 Possible Orthologues:

Collagen degradation R-HSA-1442490
ESR-mediated signaling R-HSA-8939211
Activation of Matrix Metalloproteinases R-HSA-1592389
Collagen formation R-HSA-1474290
Extra-nuclear estrogen signaling R-HSA-9009391
Extracellular matrix organization R-HSA-1474244
Signal Transduction R-HSA-162582
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Signaling by Nuclear Receptors R-HSA-9006931
Degradation of the extracellular matrix R-HSA-1474228
Activation of Matrix Metalloproteinases R-HSA-1592389
Signaling by Nuclear Receptors R-HSA-9006931
Collagen formation R-HSA-1474290
Degradation of the extracellular matrix R-HSA-1474228
Extra-nuclear estrogen signaling R-HSA-9009391
ESR-mediated signaling R-HSA-8939211
Signal Transduction R-HSA-162582
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Extracellular matrix organization R-HSA-1474244
Collagen degradation R-HSA-1442490
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
ESR-mediated signaling R-HSA-8939211
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Signaling by Nuclear Receptors R-HSA-9006931
Signal Transduction R-HSA-162582
Collagen formation R-HSA-1474290
Extracellular matrix organization R-HSA-1474244
Extra-nuclear estrogen signaling R-HSA-9009391
Activation of Matrix Metalloproteinases R-HSA-1592389
Collagen formation R-HSA-1474290
Extracellular matrix organization R-HSA-1474244
ESR-mediated signaling R-HSA-8939211
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Signal Transduction R-HSA-162582
Extra-nuclear estrogen signaling R-HSA-9009391
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Signaling by Nuclear Receptors R-HSA-9006931
Collagen formation R-HSA-1474290
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
Collagen degradation R-HSA-1442490
ESR-mediated signaling R-HSA-8939211
Extra-nuclear estrogen signaling R-HSA-9009391
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Signal Transduction R-HSA-162582
Extracellular matrix organization R-HSA-1474244
Collagen degradation R-HSA-1442490
ESR-mediated signaling R-HSA-8939211
Degradation of the extracellular matrix R-HSA-1474228
Signaling by Nuclear Receptors R-HSA-9006931
Extra-nuclear estrogen signaling R-HSA-9009391
Collagen formation R-HSA-1474290
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Activation of Matrix Metalloproteinases R-HSA-1592389
Collagen degradation R-HSA-1442490
Collagen formation R-HSA-1474290
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Signal Transduction R-HSA-162582
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Nuclear Receptors R-HSA-9006931
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Activation of Matrix Metalloproteinases R-HSA-1592389
ESR-mediated signaling R-HSA-8939211
Signaling by Nuclear Receptors R-HSA-9006931
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Collagen degradation R-HSA-1442490
Signal Transduction R-HSA-162582
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Collagen formation R-HSA-1474290
ESR-mediated signaling R-HSA-8939211
Degradation of the extracellular matrix R-HSA-1474228
Extra-nuclear estrogen signaling R-HSA-9009391
Extra-nuclear estrogen signaling R-HSA-9009391
Collagen formation R-HSA-1474290
Signal Transduction R-HSA-162582
Degradation of the extracellular matrix R-HSA-1474228
ESR-mediated signaling R-HSA-8939211
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Collagen degradation R-HSA-1442490
Signaling by Nuclear Receptors R-HSA-9006931
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Extra-nuclear estrogen signaling R-HSA-9009391
ESR-mediated signaling R-HSA-8939211
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
Collagen formation R-HSA-1474290
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Signaling by Nuclear Receptors R-HSA-9006931
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490

Expression Atlas ENSG00000137673
NCBI gene (formerly Entrezgene) 4316
GeneCards 7174
HGNC Symbol HGNC:7174
MIM gene 178990
UniProtKB Gene Name P09237
WikiGene 4316
Gene: MMP8
Ensembl ID : ENSG00000118113
Description: matrix metallopeptidase 8
Gene Synonyms: CLG1
3 APIs:
111 Possible Orthologues:

Innate Immune System R-HSA-168249
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Neutrophil degranulation R-HSA-6798695
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Degradation of the extracellular matrix R-HSA-1474228
Activation of Matrix Metalloproteinases R-HSA-1592389
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Collagen degradation R-HSA-1442490
Immune System R-HSA-168256
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Neutrophil degranulation R-HSA-6798695
Collagen degradation R-HSA-1442490
Innate Immune System R-HSA-168249
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Neutrophil degranulation R-HSA-6798695
Collagen degradation R-HSA-1442490
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Activation of Matrix Metalloproteinases R-HSA-1592389
Collagen degradation R-HSA-1442490
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Degradation of the extracellular matrix R-HSA-1474228
Immune System R-HSA-168256
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Neutrophil degranulation R-HSA-6798695
Activation of Matrix Metalloproteinases R-HSA-1592389
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Extracellular matrix organization R-HSA-1474244
Innate Immune System R-HSA-168249
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Immune System R-HSA-168256
Activation of Matrix Metalloproteinases R-HSA-1592389
Collagen degradation R-HSA-1442490
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695

Expression Atlas ENSG00000118113
NCBI gene (formerly Entrezgene) 4317
GeneCards 7175
HGNC Symbol HGNC:7175
MIM gene 120355
UniProtKB Gene Name P22894
WikiGene 4317
Gene: PSMD11
Ensembl ID : ENSG00000108671
Description: proteasome 26S subunit, non-ATPase 11
Gene Synonyms: MGC3844,P44.5,RPN6,S9
5 APIs:
283 Possible Orthologues:

DNA Replication R-HSA-69306
Metabolism R-HSA-1430728
Programmed Cell Death R-HSA-5357801
Adaptive Immune System R-HSA-1280218
Activation of NF-kappaB in B cells R-HSA-1169091
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nuclear events mediated by NFE2L2 R-HSA-9759194
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of GLI1 by the proteasome R-HSA-5610780
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
MAPK family signaling cascades R-HSA-5683057
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'on' state R-HSA-5632684
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX1 R-HSA-8878171
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
Intracellular signaling by second messengers R-HSA-9006925
Separation of Sister Chromatids R-HSA-2467813
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle, Mitotic R-HSA-69278
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by WNT R-HSA-195721
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RAF/MAP kinase cascade R-HSA-5673001
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Hedgehog R-HSA-5358351
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
S Phase R-HSA-69242
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Immune System R-HSA-168256
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of RNA R-HSA-8953854
Stabilization of p53 R-HSA-69541
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular response to hypoxia R-HSA-1234174
Mitotic G1 phase and G1/S transition R-HSA-453279
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Downstream TCR signaling R-HSA-202424
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vpu mediated degradation of CD4 R-HSA-180534
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog 'off' state R-HSA-5610787
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism R-HSA-1430728
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
HIV Infection R-HSA-162906
ER-Phagosome pathway R-HSA-1236974
Apoptosis R-HSA-109581
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by NOTCH4 R-HSA-9013694
Neutrophil degranulation R-HSA-6798695
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
p53-Dependent G1 DNA Damage Response R-HSA-69563
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disease R-HSA-1643685
G1/S DNA Damage Checkpoints R-HSA-69615
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
Metabolism of polyamines R-HSA-351202
Deubiquitination R-HSA-5688426
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Metaphase and Anaphase R-HSA-2555396
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cyclin E associated events during G1/S transition R-HSA-69202
G2/M Transition R-HSA-69275
Degradation of AXIN R-HSA-4641257
Assembly of the pre-replicative complex R-HSA-68867
Hh mutants are degraded by ERAD R-HSA-5362768
Vif-mediated degradation of APOBEC3G R-HSA-180585
Generic Transcription Pathway R-HSA-212436
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stress R-HSA-2262752
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
Signal Transduction R-HSA-162582
Mitotic Anaphase R-HSA-68882
Ub-specific processing proteases R-HSA-5689880
TCR signaling R-HSA-202403
Cell Cycle Checkpoints R-HSA-69620
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RUNX3 expression and activity R-HSA-8941858
DNA Replication Pre-Initiation R-HSA-69002
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI2 by the proteasome R-HSA-5610783
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX2 R-HSA-8878166
ABC transporter disorders R-HSA-5619084
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX3 R-HSA-8878159
Defective CFTR causes cystic fibrosis R-HSA-5678895
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Gene expression (Transcription) R-HSA-74160
Signaling by ROBO receptors R-HSA-376176
Regulation of Apoptosis R-HSA-169911
UCH proteinases R-HSA-5689603
Cytokine Signaling in Immune system R-HSA-1280215
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
Hh mutants abrogate ligand secretion R-HSA-5387390
Synthesis of DNA R-HSA-69239
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of amino acids and derivatives R-HSA-71291
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Host Interactions of HIV factors R-HSA-162909
Nervous system development R-HSA-9675108
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Neddylation R-HSA-8951664
Negative regulation of NOTCH4 signaling R-HSA-9604323
MAPK6/MAPK4 signaling R-HSA-5687128
M Phase R-HSA-68886
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Dependent G1 DNA Damage Response R-HSA-69563
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI2 by the proteasome R-HSA-5610783
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
FCERI mediated NF-kB activation R-HSA-2871837
Programmed Cell Death R-HSA-5357801
DNA Replication R-HSA-69306
C-type lectin receptors (CLRs) R-HSA-5621481
Host Interactions of HIV factors R-HSA-162909
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCR signaling R-HSA-202403
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
Hedgehog 'on' state R-HSA-5632684
Mitotic Metaphase and Anaphase R-HSA-2555396
M Phase R-HSA-68886
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
Apoptosis R-HSA-109581
Disease R-HSA-1643685
Transcriptional regulation by RUNX3 R-HSA-8878159
Assembly of the pre-replicative complex R-HSA-68867
Deubiquitination R-HSA-5688426
Downstream TCR signaling R-HSA-202424
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Anaphase R-HSA-68882
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of DVL R-HSA-4641258
MAPK family signaling cascades R-HSA-5683057
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI1 by the proteasome R-HSA-5610780
RAF/MAP kinase cascade R-HSA-5673001
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle R-HSA-1640170
Metabolism of RNA R-HSA-8953854
Activation of NF-kappaB in B cells R-HSA-1169091
Hedgehog 'off' state R-HSA-5610787
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by NOTCH R-HSA-157118
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S DNA Damage Checkpoints R-HSA-69615
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Negative regulation of NOTCH4 signaling R-HSA-9604323
Neutrophil degranulation R-HSA-6798695
Gene expression (Transcription) R-HSA-74160
ABC transporter disorders R-HSA-5619084
Transport of small molecules R-HSA-382551
ER-Phagosome pathway R-HSA-1236974
Developmental Biology R-HSA-1266738
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Generic Transcription Pathway R-HSA-212436
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Interleukins R-HSA-449147
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
PIP3 activates AKT signaling R-HSA-1257604
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
Neddylation R-HSA-8951664
Vif-mediated degradation of APOBEC3G R-HSA-180585
Nervous system development R-HSA-9675108
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of proteins R-HSA-392499
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
Disorders of transmembrane transporters R-HSA-5619115
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle Checkpoints R-HSA-69620
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Cellular responses to stimuli R-HSA-8953897
Orc1 removal from chromatin R-HSA-68949
Metabolism of amino acids and derivatives R-HSA-71291
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle, Mitotic R-HSA-69278
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of polyamines R-HSA-351202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants are degraded by ERAD R-HSA-5362768
HIV Infection R-HSA-162906
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RAS by GAPs R-HSA-5658442
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
Cellular response to hypoxia R-HSA-1234174
Cellular response to chemical stress R-HSA-9711123
S Phase R-HSA-69242
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
Adaptive Immune System R-HSA-1280218
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Post-translational protein modification R-HSA-597592
Cellular responses to stress R-HSA-2262752
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S Transition R-HSA-69206
Synthesis of DNA R-HSA-69239
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Class I MHC mediated antigen processing & presentation R-HSA-983169
Intracellular signaling by second messengers R-HSA-9006925
PCP/CE pathway R-HSA-4086400
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by ROBO receptors R-HSA-376176
Mitotic G2-G2/M phases R-HSA-453274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH4 R-HSA-9013694
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mitotic cell cycle R-HSA-453276
Orc1 removal from chromatin R-HSA-68949
Vif-mediated degradation of APOBEC3G R-HSA-180585
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'on' state R-HSA-5632684
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Innate Immune System R-HSA-168249
Degradation of DVL R-HSA-4641258
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Cell Cycle, Mitotic R-HSA-69278
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by the B Cell Receptor (BCR) R-HSA-983705
KEAP1-NFE2L2 pathway R-HSA-9755511
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI2 by the proteasome R-HSA-5610783
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
Infectious disease R-HSA-5663205
Mitotic Metaphase and Anaphase R-HSA-2555396
DNA Replication Pre-Initiation R-HSA-69002
Class I MHC mediated antigen processing & presentation R-HSA-983169
Gene expression (Transcription) R-HSA-74160
Regulation of Apoptosis R-HSA-169911
Cellular response to chemical stress R-HSA-9711123
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Asymmetric localization of PCP proteins R-HSA-4608870
Neutrophil degranulation R-HSA-6798695
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ER-Phagosome pathway R-HSA-1236974
Signal Transduction R-HSA-162582
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by ROBO receptors R-HSA-376176
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RNA Polymerase II Transcription R-HSA-73857
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
TCR signaling R-HSA-202403
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX1 R-HSA-8878171
Intracellular signaling by second messengers R-HSA-9006925
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of proteins R-HSA-392499
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX3 expression and activity R-HSA-8941858
p53-Dependent G1 DNA Damage Response R-HSA-69563
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Independent DNA Damage Response R-HSA-69610
G1/S DNA Damage Checkpoints R-HSA-69615
Deubiquitination R-HSA-5688426
M Phase R-HSA-68886
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
Generic Transcription Pathway R-HSA-212436
Downstream TCR signaling R-HSA-202424
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Vpu mediated degradation of CD4 R-HSA-180534
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'off' state R-HSA-5610787
Nervous system development R-HSA-9675108
Cellular responses to stimuli R-HSA-8953897
Hedgehog ligand biogenesis R-HSA-5358346
Interleukin-1 signaling R-HSA-9020702
Separation of Sister Chromatids R-HSA-2467813
MAPK1/MAPK3 signaling R-HSA-5684996
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of GLI1 by the proteasome R-HSA-5610780
Mitotic G2-G2/M phases R-HSA-453274
UCH proteinases R-HSA-5689603
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of RNA R-HSA-8953854
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Stabilization of p53 R-HSA-69541
Regulation of RUNX2 expression and activity R-HSA-8939902
Programmed Cell Death R-HSA-5357801
Cell Cycle R-HSA-1640170
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cytokine Signaling in Immune system R-HSA-1280215
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
G2/M Transition R-HSA-69275
Disease R-HSA-1643685
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1/S Transition R-HSA-69206
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC-family proteins mediated transport R-HSA-382556
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic G1 phase and G1/S transition R-HSA-453279
Ub-specific processing proteases R-HSA-5689880
Disorders of transmembrane transporters R-HSA-5619115
Signaling by WNT R-HSA-195721
DNA Replication R-HSA-69306
ABC transporter disorders R-HSA-5619084
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to hypoxia R-HSA-1234174
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
Synthesis of DNA R-HSA-69239
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PCP/CE pathway R-HSA-4086400
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Interleukin-1 family signaling R-HSA-446652
Disorders of transmembrane transporters R-HSA-5619115
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
Mitotic Anaphase R-HSA-68882
Hh mutants are degraded by ERAD R-HSA-5362768
Adaptive Immune System R-HSA-1280218
MAPK6/MAPK4 signaling R-HSA-5687128
Asymmetric localization of PCP proteins R-HSA-4608870
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of AXIN R-HSA-4641257
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Defective CFTR causes cystic fibrosis R-HSA-5678895
HIV Infection R-HSA-162906
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
DNA Replication R-HSA-69306
Cellular responses to stimuli R-HSA-8953897
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of polyamines R-HSA-351202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
ABC-family proteins mediated transport R-HSA-382556
Activation of NF-kappaB in B cells R-HSA-1169091
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Developmental Biology R-HSA-1266738
Deubiquitination R-HSA-5688426
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by ROBO receptors R-HSA-376176
Separation of Sister Chromatids R-HSA-2467813
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by NOTCH R-HSA-157118
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Programmed Cell Death R-HSA-5357801
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
Class I MHC mediated antigen processing & presentation R-HSA-983169
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RUNX3 expression and activity R-HSA-8941858
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 signaling R-HSA-9020702
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated NF-kB activation R-HSA-2871837
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Generic Transcription Pathway R-HSA-212436
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Signaling by Interleukins R-HSA-449147
MAPK family signaling cascades R-HSA-5683057
Degradation of DVL R-HSA-4641258
Beta-catenin independent WNT signaling R-HSA-3858494
Innate Immune System R-HSA-168249
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Apoptosis R-HSA-109581
Intracellular signaling by second messengers R-HSA-9006925
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vpu mediated degradation of CD4 R-HSA-180534
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH4 R-HSA-9013694
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
RNA Polymerase II Transcription R-HSA-73857
Assembly of the pre-replicative complex R-HSA-68867
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Transition R-HSA-69275
Gene expression (Transcription) R-HSA-74160
Mitotic G1 phase and G1/S transition R-HSA-453279
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Synthesis of DNA R-HSA-69239
Cellular response to chemical stress R-HSA-9711123
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Axon guidance R-HSA-422475
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of Apoptosis R-HSA-169911
Immune System R-HSA-168256
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC transporter disorders R-HSA-5619084
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by WNT R-HSA-195721
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Hedgehog R-HSA-5358351
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Neddylation R-HSA-8951664
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Orc1 removal from chromatin R-HSA-68949
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
Stabilization of p53 R-HSA-69541
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
PIP3 activates AKT signaling R-HSA-1257604
G1/S DNA Damage Checkpoints R-HSA-69615
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog ligand biogenesis R-HSA-5358346
PCP/CE pathway R-HSA-4086400
Neutrophil degranulation R-HSA-6798695
Hedgehog 'on' state R-HSA-5632684
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Disease R-HSA-1643685
PTEN Regulation R-HSA-6807070
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S Transition R-HSA-69206
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of amino acids and derivatives R-HSA-71291
UCH proteinases R-HSA-5689603
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Switching of origins to a post-replicative state R-HSA-69052
Downstream TCR signaling R-HSA-202424
Cell Cycle Checkpoints R-HSA-69620
Post-translational protein modification R-HSA-597592
M Phase R-HSA-68886
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle R-HSA-1640170
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Neddylation R-HSA-8951664
Switching of origins to a post-replicative state R-HSA-69052
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle Checkpoints R-HSA-69620
ABC-family proteins mediated transport R-HSA-382556
Neutrophil degranulation R-HSA-6798695
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hh mutants are degraded by ERAD R-HSA-5362768
HIV Infection R-HSA-162906
Hedgehog 'on' state R-HSA-5632684
Mitotic G2-G2/M phases R-HSA-453274
Degradation of beta-catenin by the destruction complex R-HSA-195253
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 signaling R-HSA-9020702
Degradation of AXIN R-HSA-4641257
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of GLI2 by the proteasome R-HSA-5610783
Downstream TCR signaling R-HSA-202424
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle R-HSA-1640170
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
DNA Replication R-HSA-69306
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'off' state R-HSA-5610787
Regulation of Apoptosis R-HSA-169911
Generic Transcription Pathway R-HSA-212436
Programmed Cell Death R-HSA-5357801
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to chemical stress R-HSA-9711123
Intracellular signaling by second messengers R-HSA-9006925
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
Signal Transduction R-HSA-162582
Regulation of expression of SLITs and ROBOs R-HSA-9010553
UCH proteinases R-HSA-5689603
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Adaptive Immune System R-HSA-1280218
PTEN Regulation R-HSA-6807070
Degradation of GLI1 by the proteasome R-HSA-5610780
M Phase R-HSA-68886
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX3 R-HSA-8878159
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Disease R-HSA-1643685
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic Metaphase and Anaphase R-HSA-2555396
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of mitotic cell cycle R-HSA-453276
p53-Independent DNA Damage Response R-HSA-69610
Nervous system development R-HSA-9675108
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TCR signaling R-HSA-202403
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ER-Phagosome pathway R-HSA-1236974
Orc1 removal from chromatin R-HSA-68949
Cytokine Signaling in Immune system R-HSA-1280215
MAPK family signaling cascades R-HSA-5683057
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Nuclear events mediated by NFE2L2 R-HSA-9759194
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ub-specific processing proteases R-HSA-5689880
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Interleukins R-HSA-449147
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Developmental Biology R-HSA-1266738
Immune System R-HSA-168256
Disorders of transmembrane transporters R-HSA-5619115
Cyclin E associated events during G1/S transition R-HSA-69202
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic Anaphase R-HSA-68882
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants abrogate ligand secretion R-HSA-5387390
Deubiquitination R-HSA-5688426
PIP3 activates AKT signaling R-HSA-1257604
Host Interactions of HIV factors R-HSA-162909
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC transporter disorders R-HSA-5619084
Signaling by WNT R-HSA-195721
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX2 expression and activity R-HSA-8939902
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RAS by GAPs R-HSA-5658442
Innate Immune System R-HSA-168249
CLEC7A (Dectin-1) signaling R-HSA-5607764
G2/M Checkpoints R-HSA-69481
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by ROBO receptors R-HSA-376176
Signaling by NOTCH4 R-HSA-9013694
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
S Phase R-HSA-69242
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Post-translational protein modification R-HSA-597592
Synthesis of DNA R-HSA-69239
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
Cellular responses to stress R-HSA-2262752
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular responses to stimuli R-HSA-8953897
G2/M Transition R-HSA-69275
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Asymmetric localization of PCP proteins R-HSA-4608870
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of polyamines R-HSA-351202
Transport of small molecules R-HSA-382551
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S Transition R-HSA-69206
Gene expression (Transcription) R-HSA-74160
Interleukin-1 family signaling R-HSA-446652
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Assembly of the pre-replicative complex R-HSA-68867
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RNA Polymerase II Transcription R-HSA-73857
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Axon guidance R-HSA-422475
Apoptosis R-HSA-109581
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of RNA R-HSA-8953854
Metabolism of proteins R-HSA-392499
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX3 expression and activity R-HSA-8941858
Programmed Cell Death R-HSA-5357801
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of AXIN R-HSA-4641257
Axon guidance R-HSA-422475
Hedgehog 'on' state R-HSA-5632684
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of RUNX2 expression and activity R-HSA-8939902
Generic Transcription Pathway R-HSA-212436
Downstream TCR signaling R-HSA-202424
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by Hedgehog R-HSA-5358351
p53-Independent DNA Damage Response R-HSA-69610
Gene expression (Transcription) R-HSA-74160
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH4 R-HSA-9013694
ER-Phagosome pathway R-HSA-1236974
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI1 by the proteasome R-HSA-5610780
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
FCERI mediated NF-kB activation R-HSA-2871837
Class I MHC mediated antigen processing & presentation R-HSA-983169
Assembly of the pre-replicative complex R-HSA-68867
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Disorders of transmembrane transporters R-HSA-5619115
Negative regulation of NOTCH4 signaling R-HSA-9604323
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Adaptive Immune System R-HSA-1280218
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Activation of NF-kappaB in B cells R-HSA-1169091
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Post-translational protein modification R-HSA-597592
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Nuclear events mediated by NFE2L2 R-HSA-9759194
DNA Replication R-HSA-69306
Infectious disease R-HSA-5663205
HIV Infection R-HSA-162906
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX1 R-HSA-8878171
C-type lectin receptors (CLRs) R-HSA-5621481
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle, Mitotic R-HSA-69278
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'off' state R-HSA-5610787
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of DVL R-HSA-4641258
Signaling by WNT R-HSA-195721
Ub-specific processing proteases R-HSA-5689880
Neddylation R-HSA-8951664
Apoptosis R-HSA-109581
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
ABC transporter disorders R-HSA-5619084
Interleukin-1 signaling R-HSA-9020702
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Transition R-HSA-69275
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stimuli R-HSA-8953897
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
ABC-family proteins mediated transport R-HSA-382556
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by Interleukins R-HSA-449147
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
TCF dependent signaling in response to WNT R-HSA-201681
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Developmental Biology R-HSA-1266738
G2/M Checkpoints R-HSA-69481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RAS by GAPs R-HSA-5658442
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle R-HSA-1640170
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle Checkpoints R-HSA-69620
Neutrophil degranulation R-HSA-6798695
Metabolism R-HSA-1430728
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by ROBO receptors R-HSA-376176
Antigen processing-Cross presentation R-HSA-1236975
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
M Phase R-HSA-68886
Intracellular signaling by second messengers R-HSA-9006925
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Regulation of Apoptosis R-HSA-169911
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Anaphase R-HSA-68882
Regulation of PTEN stability and activity R-HSA-8948751
Switching of origins to a post-replicative state R-HSA-69052
Immune System R-HSA-168256
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
TCR signaling R-HSA-202403
Synthesis of DNA R-HSA-69239
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic Metaphase and Anaphase R-HSA-2555396
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX3 R-HSA-8878159
Host Interactions of HIV factors R-HSA-162909
Disease R-HSA-1643685
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vpu mediated degradation of CD4 R-HSA-180534
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nervous system development R-HSA-9675108
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G1/S Transition R-HSA-69206
Metabolism of polyamines R-HSA-351202
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of RNA R-HSA-8953854
Signaling by WNT R-HSA-195721
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of GLI2 by the proteasome R-HSA-5610783
Nervous system development R-HSA-9675108
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of amino acids and derivatives R-HSA-71291
TCR signaling R-HSA-202403
Synthesis of DNA R-HSA-69239
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
MAPK family signaling cascades R-HSA-5683057
Degradation of DVL R-HSA-4641258
Adaptive Immune System R-HSA-1280218
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
FCERI mediated NF-kB activation R-HSA-2871837
Activation of NF-kappaB in B cells R-HSA-1169091
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Axon guidance R-HSA-422475
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle, Mitotic R-HSA-69278
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Innate Immune System R-HSA-168249
Regulation of Apoptosis R-HSA-169911
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX3 R-HSA-8878159
Intracellular signaling by second messengers R-HSA-9006925
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of PTEN stability and activity R-HSA-8948751
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
Transport of small molecules R-HSA-382551
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
Deubiquitination R-HSA-5688426
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of RUNX2 expression and activity R-HSA-8939902
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Switching of origins to a post-replicative state R-HSA-69052
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
Separation of Sister Chromatids R-HSA-2467813
Defective CFTR causes cystic fibrosis R-HSA-5678895
Class I MHC mediated antigen processing & presentation R-HSA-983169
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Signaling by Interleukins R-HSA-449147
Signaling by ROBO receptors R-HSA-376176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PCP/CE pathway R-HSA-4086400
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog 'on' state R-HSA-5632684
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Neddylation R-HSA-8951664
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Gene expression (Transcription) R-HSA-74160
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
Ub-specific processing proteases R-HSA-5689880
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
HIV Infection R-HSA-162906
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Dependent G1 DNA Damage Response R-HSA-69563
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Neutrophil degranulation R-HSA-6798695
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Vif-mediated degradation of APOBEC3G R-HSA-180585
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent DNA Damage Response R-HSA-69610
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Cell Cycle Checkpoints R-HSA-69620
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Generic Transcription Pathway R-HSA-212436
Mitotic Metaphase and Anaphase R-HSA-2555396
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stimuli R-HSA-8953897
C-type lectin receptors (CLRs) R-HSA-5621481
S Phase R-HSA-69242
M Phase R-HSA-68886
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Mitotic Anaphase R-HSA-68882
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to hypoxia R-HSA-1234174
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
G2/M Checkpoints R-HSA-69481
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Cellular response to chemical stress R-HSA-9711123
Disease R-HSA-1643685
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic G1 phase and G1/S transition R-HSA-453279
Antigen processing-Cross presentation R-HSA-1236975
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
Vpu mediated degradation of CD4 R-HSA-180534
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of AXIN R-HSA-4641257
Metabolism R-HSA-1430728
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Generic Transcription Pathway R-HSA-212436
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle R-HSA-1640170
C-type lectin receptors (CLRs) R-HSA-5621481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog ligand biogenesis R-HSA-5358346
Apoptosis R-HSA-109581
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of PTEN stability and activity R-HSA-8948751
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Stabilization of p53 R-HSA-69541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ub-specific processing proteases R-HSA-5689880
G2/M Checkpoints R-HSA-69481
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by Hedgehog R-HSA-5358351
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cellular response to hypoxia R-HSA-1234174
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by NOTCH4 R-HSA-9013694
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
G2/M Transition R-HSA-69275
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC-family proteins mediated transport R-HSA-382556
Immune System R-HSA-168256
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
NIK-->noncanonical NF-kB signaling R-HSA-5676590
DNA Replication Pre-Initiation R-HSA-69002
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
S Phase R-HSA-69242
Transport of small molecules R-HSA-382551
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Deubiquitination R-HSA-5688426
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
Neddylation R-HSA-8951664
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stress R-HSA-2262752
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PTEN Regulation R-HSA-6807070
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle Checkpoints R-HSA-69620
Beta-catenin independent WNT signaling R-HSA-3858494
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Cyclin E associated events during G1/S transition R-HSA-69202
Axon guidance R-HSA-422475
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of Apoptosis R-HSA-169911
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of RNA R-HSA-8953854
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic Anaphase R-HSA-68882
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of polyamines R-HSA-351202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
HIV Infection R-HSA-162906
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Independent DNA Damage Response R-HSA-69610
PCP/CE pathway R-HSA-4086400
Nervous system development R-HSA-9675108
TCF dependent signaling in response to WNT R-HSA-201681
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Synthesis of DNA R-HSA-69239
Interleukin-1 family signaling R-HSA-446652
Signaling by ROBO receptors R-HSA-376176
M Phase R-HSA-68886
Hh mutants are degraded by ERAD R-HSA-5362768
Assembly of the pre-replicative complex R-HSA-68867
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
ABC transporter disorders R-HSA-5619084
Hedgehog 'off' state R-HSA-5610787
PIP3 activates AKT signaling R-HSA-1257604
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle, Mitotic R-HSA-69278
Adaptive Immune System R-HSA-1280218
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Cellular responses to stimuli R-HSA-8953897
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Dependent G1 DNA Damage Response R-HSA-69563
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Neutrophil degranulation R-HSA-6798695
Orc1 removal from chromatin R-HSA-68949
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hh mutants abrogate ligand secretion R-HSA-5387390
Signal Transduction R-HSA-162582
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication R-HSA-69306
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK6/MAPK4 signaling R-HSA-5687128
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI1 by the proteasome R-HSA-5610780
MAPK family signaling cascades R-HSA-5683057
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ub-specific processing proteases R-HSA-5689880
M Phase R-HSA-68886
Transcriptional regulation by RUNX3 R-HSA-8878159
Neddylation R-HSA-8951664
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of AXIN R-HSA-4641257
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream TCR signaling R-HSA-202424
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by ROBO receptors R-HSA-376176
Metabolism of proteins R-HSA-392499
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic Anaphase R-HSA-68882
Hh mutants are degraded by ERAD R-HSA-5362768
ABC transporter disorders R-HSA-5619084
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by WNT R-HSA-195721
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing-Cross presentation R-HSA-1236975
PTEN Regulation R-HSA-6807070
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of DVL R-HSA-4641258
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cell Cycle, Mitotic R-HSA-69278
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by NOTCH R-HSA-157118
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
p53-Independent DNA Damage Response R-HSA-69610
Cyclin E associated events during G1/S transition R-HSA-69202
ER-Phagosome pathway R-HSA-1236974
Neutrophil degranulation R-HSA-6798695
KEAP1-NFE2L2 pathway R-HSA-9755511
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G2/M Checkpoints R-HSA-69481
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of amino acids and derivatives R-HSA-71291
TCF dependent signaling in response to WNT R-HSA-201681
TCR signaling R-HSA-202403
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
Stabilization of p53 R-HSA-69541
PCP/CE pathway R-HSA-4086400
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
Orc1 removal from chromatin R-HSA-68949
Gene expression (Transcription) R-HSA-74160
Adaptive Immune System R-HSA-1280218
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Interleukin-1 signaling R-HSA-9020702
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G2-G2/M phases R-HSA-453274
UCH proteinases R-HSA-5689603
Innate Immune System R-HSA-168249
Separation of Sister Chromatids R-HSA-2467813
S Phase R-HSA-69242
Beta-catenin independent WNT signaling R-HSA-3858494
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Host Interactions of HIV factors R-HSA-162909
Transport of small molecules R-HSA-382551
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Vif-mediated degradation of APOBEC3G R-HSA-180585
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of beta-catenin by the destruction complex R-HSA-195253
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
RNA Polymerase II Transcription R-HSA-73857
Cellular response to hypoxia R-HSA-1234174
Assembly of the pre-replicative complex R-HSA-68867
Post-translational protein modification R-HSA-597592
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular response to chemical stress R-HSA-9711123
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stimuli R-HSA-8953897
Signaling by Interleukins R-HSA-449147
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK6/MAPK4 signaling R-HSA-5687128
Disease R-HSA-1643685
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by Hedgehog R-HSA-5358351
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle R-HSA-1640170
Deubiquitination R-HSA-5688426
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Axon guidance R-HSA-422475
ABC-family proteins mediated transport R-HSA-382556
Metabolism of RNA R-HSA-8953854
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Interleukin-1 family signaling R-HSA-446652
Hedgehog 'off' state R-HSA-5610787
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stress R-HSA-2262752
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
DNA Replication R-HSA-69306
Nuclear events mediated by NFE2L2 R-HSA-9759194
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Disorders of transmembrane transporters R-HSA-5619115
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G1/S Transition R-HSA-69206
Regulation of mitotic cell cycle R-HSA-453276
Regulation of RUNX3 expression and activity R-HSA-8941858
HIV Infection R-HSA-162906
Immune System R-HSA-168256
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism R-HSA-1430728
Orc1 removal from chromatin R-HSA-68949
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX1 R-HSA-8878171
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
Mitotic Metaphase and Anaphase R-HSA-2555396
Class I MHC mediated antigen processing & presentation R-HSA-983169
Stabilization of p53 R-HSA-69541
Synthesis of DNA R-HSA-69239
Apoptosis R-HSA-109581
Assembly of the pre-replicative complex R-HSA-68867
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic Anaphase R-HSA-68882
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle, Mitotic R-HSA-69278
Cyclin E associated events during G1/S transition R-HSA-69202
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing-Cross presentation R-HSA-1236975
Metabolism R-HSA-1430728
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX2 expression and activity R-HSA-8939902
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
Nervous system development R-HSA-9675108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle Checkpoints R-HSA-69620
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'on' state R-HSA-5632684
Neddylation R-HSA-8951664
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G1 phase and G1/S transition R-HSA-453279
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Infectious disease R-HSA-5663205
Programmed Cell Death R-HSA-5357801
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Disease R-HSA-1643685
Hedgehog 'off' state R-HSA-5610787
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PCP/CE pathway R-HSA-4086400
UCH proteinases R-HSA-5689603
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transcriptional regulation by RUNX2 R-HSA-8878166
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of DVL R-HSA-4641258
Degradation of GLI2 by the proteasome R-HSA-5610783
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G2/M Transition R-HSA-69275
Generic Transcription Pathway R-HSA-212436
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream TCR signaling R-HSA-202424
MAPK family signaling cascades R-HSA-5683057
Signaling by ROBO receptors R-HSA-376176
Separation of Sister Chromatids R-HSA-2467813
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
DNA Replication R-HSA-69306
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
S Phase R-HSA-69242
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Gene expression (Transcription) R-HSA-74160
Degradation of AXIN R-HSA-4641257
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by NOTCH R-HSA-157118
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stress R-HSA-2262752
ER-Phagosome pathway R-HSA-1236974
TCR signaling R-HSA-202403
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Axon guidance R-HSA-422475
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of RNA R-HSA-8953854
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
Cell Cycle R-HSA-1640170
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of beta-catenin by the destruction complex R-HSA-195253
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Interleukin-1 signaling R-HSA-9020702
HIV Infection R-HSA-162906
Cellular responses to stimuli R-HSA-8953897
Hedgehog ligand biogenesis R-HSA-5358346
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of PTEN stability and activity R-HSA-8948751
ABC transporter disorders R-HSA-5619084
Intracellular signaling by second messengers R-HSA-9006925
PTEN Regulation R-HSA-6807070
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Host Interactions of HIV factors R-HSA-162909
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neutrophil degranulation R-HSA-6798695
Transcriptional regulation by RUNX3 R-HSA-8878159
Signal Transduction R-HSA-162582
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of polyamines R-HSA-351202
Metabolism of proteins R-HSA-392499
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Adaptive Immune System R-HSA-1280218
Deubiquitination R-HSA-5688426
G1/S DNA Damage Checkpoints R-HSA-69615
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1 DNA Damage Response R-HSA-69563
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH4 R-HSA-9013694
Cytokine Signaling in Immune system R-HSA-1280215
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Cellular responses to stress R-HSA-2262752
Neddylation R-HSA-8951664
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Class I MHC mediated antigen processing & presentation R-HSA-983169
TCR signaling R-HSA-202403
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by ROBO receptors R-HSA-376176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
Hedgehog 'on' state R-HSA-5632684
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by NOTCH R-HSA-157118
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Synthesis of DNA R-HSA-69239
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Neutrophil degranulation R-HSA-6798695
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
Adaptive Immune System R-HSA-1280218
Signaling by the B Cell Receptor (BCR) R-HSA-983705
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Degradation of GLI1 by the proteasome R-HSA-5610780
ABC-family proteins mediated transport R-HSA-382556
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Host Interactions of HIV factors R-HSA-162909
FCERI mediated NF-kB activation R-HSA-2871837
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
Developmental Biology R-HSA-1266738
Metabolism of RNA R-HSA-8953854
UCH proteinases R-HSA-5689603
Cytokine Signaling in Immune system R-HSA-1280215
Vpu mediated degradation of CD4 R-HSA-180534
RNA Polymerase II Transcription R-HSA-73857
Signaling by NOTCH4 R-HSA-9013694
Innate Immune System R-HSA-168249
PIP3 activates AKT signaling R-HSA-1257604
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Gene expression (Transcription) R-HSA-74160
Transport of small molecules R-HSA-382551
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle Checkpoints R-HSA-69620
Hh mutants are degraded by ERAD R-HSA-5362768
M Phase R-HSA-68886
Interleukin-1 family signaling R-HSA-446652
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK family signaling cascades R-HSA-5683057
PCP/CE pathway R-HSA-4086400
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of DVL R-HSA-4641258
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of polyamines R-HSA-351202
G2/M Checkpoints R-HSA-69481
C-type lectin receptors (CLRs) R-HSA-5621481
ABC transporter disorders R-HSA-5619084
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ub-specific processing proteases R-HSA-5689880
Hedgehog 'off' state R-HSA-5610787
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RAS by GAPs R-HSA-5658442
Stabilization of p53 R-HSA-69541
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Independent DNA Damage Response R-HSA-69610
Beta-catenin independent WNT signaling R-HSA-3858494
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Immune System R-HSA-168256
TCF dependent signaling in response to WNT R-HSA-201681
Cellular response to chemical stress R-HSA-9711123
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Axon guidance R-HSA-422475
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic Anaphase R-HSA-68882
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
Cell Cycle R-HSA-1640170
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transcriptional regulation by RUNX3 R-HSA-8878159
Generic Transcription Pathway R-HSA-212436
Activation of NF-kappaB in B cells R-HSA-1169091
S Phase R-HSA-69242
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Programmed Cell Death R-HSA-5357801
Intracellular signaling by second messengers R-HSA-9006925
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
Nervous system development R-HSA-9675108
Downstream TCR signaling R-HSA-202424
Post-translational protein modification R-HSA-597592
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism R-HSA-1430728
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
HIV Infection R-HSA-162906
Cellular response to hypoxia R-HSA-1234174
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
KEAP1-NFE2L2 pathway R-HSA-9755511
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vif-mediated degradation of APOBEC3G R-HSA-180585
Assembly of the pre-replicative complex R-HSA-68867
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hedgehog ligand biogenesis R-HSA-5358346
G1/S Transition R-HSA-69206
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of PTEN stability and activity R-HSA-8948751
PTEN Regulation R-HSA-6807070
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by WNT R-HSA-195721
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent G1/S DNA damage checkpoint R-HSA-69613

Expression Atlas ENSG00000108671
NCBI gene (formerly Entrezgene) 5717
GeneCards 9556
HGNC Symbol HGNC:9556
MIM gene 604449
UniProtKB Gene Name O00231
WikiGene 5717
Gene: PSEN2
Ensembl ID : ENSG00000143801
Description: presenilin 2
Gene Synonyms: AD3L,AD4,E5-1,PS-2,PS2,STM2
5 APIs:
205 Possible Orthologues:

NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH4 R-HSA-9013694
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
Nervous system development R-HSA-9675108
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH3 R-HSA-9012852
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Nuclear signaling by ERBB4 R-HSA-1251985
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by ERBB4 R-HSA-1236394
Disease R-HSA-1643685
Noncanonical activation of NOTCH3 R-HSA-9017802
EPH-Ephrin signaling R-HSA-2682334
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Axon guidance R-HSA-422475
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signal Transduction R-HSA-162582
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 R-HSA-1980143
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Nervous system development R-HSA-9675108
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Axon guidance R-HSA-422475
Signaling by NOTCH3 R-HSA-9012852
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH2 R-HSA-1980145
p75 NTR receptor-mediated signalling R-HSA-193704
Death Receptor Signaling R-HSA-73887
EPH-Ephrin signaling R-HSA-2682334
Noncanonical activation of NOTCH3 R-HSA-9017802
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Developmental Biology R-HSA-1266738
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NRIF signals cell death from the nucleus R-HSA-205043
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH4 R-HSA-9013694
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH2 R-HSA-1980145
Nuclear signaling by ERBB4 R-HSA-1251985
Signal Transduction R-HSA-162582
EPH-Ephrin signaling R-HSA-2682334
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 R-HSA-1980143
Signaling by ERBB4 R-HSA-1236394
Noncanonical activation of NOTCH3 R-HSA-9017802
Axon guidance R-HSA-422475
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH3 R-HSA-9012852
NRIF signals cell death from the nucleus R-HSA-205043
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Death Receptor Signaling R-HSA-73887
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
p75 NTR receptor-mediated signalling R-HSA-193704
Developmental Biology R-HSA-1266738
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by ERBB4 R-HSA-1236394
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH2 R-HSA-1980145
Noncanonical activation of NOTCH3 R-HSA-9017802
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Nervous system development R-HSA-9675108
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 in Cancer R-HSA-2644603
EPH-Ephrin signaling R-HSA-2682334
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
p75 NTR receptor-mediated signalling R-HSA-193704
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH3 R-HSA-9012852
EPH-Ephrin signaling R-HSA-2682334
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Noncanonical activation of NOTCH3 R-HSA-9017802
Regulated proteolysis of p75NTR R-HSA-193692
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Axon guidance R-HSA-422475
Signaling by ERBB4 R-HSA-1236394
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH R-HSA-157118
NRIF signals cell death from the nucleus R-HSA-205043
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH2 R-HSA-1980145
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
Nuclear signaling by ERBB4 R-HSA-1251985
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Disease R-HSA-1643685
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nuclear signaling by ERBB4 R-HSA-1251985
Nervous system development R-HSA-9675108
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH3 R-HSA-9012852
Signaling by ERBB4 R-HSA-1236394
Axon guidance R-HSA-422475
Noncanonical activation of NOTCH3 R-HSA-9017802
p75 NTR receptor-mediated signalling R-HSA-193704
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH R-HSA-157118
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH2 R-HSA-1980145
Signal Transduction R-HSA-162582
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Death Receptor Signaling R-HSA-73887
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 in Cancer R-HSA-2644603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 in Cancer R-HSA-2644603
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Noncanonical activation of NOTCH3 R-HSA-9017802
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH3 R-HSA-9012852
Disease R-HSA-1643685
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Developmental Biology R-HSA-1266738
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 R-HSA-1980143
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by ERBB4 R-HSA-1236394
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Nuclear signaling by ERBB4 R-HSA-1251985
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Axon guidance R-HSA-422475
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EPH-Ephrin signaling R-HSA-2682334
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 in Cancer R-HSA-2644603
Noncanonical activation of NOTCH3 R-HSA-9017802
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH3 R-HSA-9012852
Nervous system development R-HSA-9675108
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Death Receptor Signaling R-HSA-73887
Signal Transduction R-HSA-162582
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH1 R-HSA-1980143
p75 NTR receptor-mediated signalling R-HSA-193704
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by ERBB4 R-HSA-1236394
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 in Cancer R-HSA-2644603
p75 NTR receptor-mediated signalling R-HSA-193704
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Nervous system development R-HSA-9675108
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 R-HSA-1980143
Signaling by ERBB4 R-HSA-1236394
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Signaling by NOTCH3 R-HSA-9012852
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH2 R-HSA-1980145
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Developmental Biology R-HSA-1266738
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Nuclear signaling by ERBB4 R-HSA-1251985
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 in Cancer R-HSA-2644603
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
NRIF signals cell death from the nucleus R-HSA-205043
Axon guidance R-HSA-422475
Signaling by NOTCH2 R-HSA-1980145
Disease R-HSA-1643685
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by ERBB4 R-HSA-1236394
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
p75 NTR receptor-mediated signalling R-HSA-193704
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 R-HSA-1980143
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH4 R-HSA-9013694
Nuclear signaling by ERBB4 R-HSA-1251985
Death Receptor Signaling R-HSA-73887
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096

Expression Atlas ENSG00000143801
LRG display in Ensembl gene LRG_225
NCBI gene (formerly Entrezgene) 5664
GeneCards 9509
HGNC Symbol HGNC:9509
MIM gene 600759
MIM morbid 613697
UniProtKB Gene Name P49810
WikiGene 5664
Gene: BCL2
Ensembl ID : ENSG00000171791
Description: BCL2 apoptosis regulator
Gene Synonyms: BCL-2,PPP1R50
4 APIs:
228 Possible Orthologues:

Intrinsic Pathway for Apoptosis R-HSA-109606
Signal Transduction R-HSA-162582
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453
Inflammasomes R-HSA-622312
Signaling by Nuclear Receptors R-HSA-9006931
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Activation of BH3-only proteins R-HSA-114452
Programmed Cell Death R-HSA-5357801
Extra-nuclear estrogen signaling R-HSA-9009391
Activation of BAD and translocation to mitochondria R-HSA-111447
The NLRP1 inflammasome R-HSA-844455
Cytokine Signaling in Immune system R-HSA-1280215
Estrogen-dependent gene expression R-HSA-9018519
Apoptosis R-HSA-109581
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
ESR-mediated signaling R-HSA-8939211
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Innate Immune System R-HSA-168249
Programmed Cell Death R-HSA-5357801
ESR-mediated signaling R-HSA-8939211
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453
Activation of BAD and translocation to mitochondria R-HSA-111447
Intrinsic Pathway for Apoptosis R-HSA-109606
Inflammasomes R-HSA-622312
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
Activation of BH3-only proteins R-HSA-114452
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cytokine Signaling in Immune system R-HSA-1280215
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Immune System R-HSA-168256
Extra-nuclear estrogen signaling R-HSA-9009391
Estrogen-dependent gene expression R-HSA-9018519
The NLRP1 inflammasome R-HSA-844455
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Interleukins R-HSA-449147
Apoptosis R-HSA-109581
Estrogen-dependent gene expression R-HSA-9018519
Intrinsic Pathway for Apoptosis R-HSA-109606
Innate Immune System R-HSA-168249
Apoptosis R-HSA-109581
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
ESR-mediated signaling R-HSA-8939211
Immune System R-HSA-168256
The NLRP1 inflammasome R-HSA-844455
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Extra-nuclear estrogen signaling R-HSA-9009391
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Activation of BH3-only proteins R-HSA-114452
Programmed Cell Death R-HSA-5357801
Inflammasomes R-HSA-622312
Signaling by Interleukins R-HSA-449147
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453
Activation of BAD and translocation to mitochondria R-HSA-111447
Signaling by Nuclear Receptors R-HSA-9006931
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Immune System R-HSA-168256
Activation of BAD and translocation to mitochondria R-HSA-111447
Inflammasomes R-HSA-622312
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Estrogen-dependent gene expression R-HSA-9018519
The NLRP1 inflammasome R-HSA-844455
Apoptosis R-HSA-109581
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Intrinsic Pathway for Apoptosis R-HSA-109606
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Nuclear Receptors R-HSA-9006931
Activation of BH3-only proteins R-HSA-114452
Signaling by Interleukins R-HSA-449147
ESR-mediated signaling R-HSA-8939211
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453
Programmed Cell Death R-HSA-5357801
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Interleukins R-HSA-449147
The NLRP1 inflammasome R-HSA-844455
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Innate Immune System R-HSA-168249
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Activation of BH3-only proteins R-HSA-114452
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453
ESR-mediated signaling R-HSA-8939211
Immune System R-HSA-168256
Estrogen-dependent gene expression R-HSA-9018519
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Intrinsic Pathway for Apoptosis R-HSA-109606
Apoptosis R-HSA-109581
Activation of BAD and translocation to mitochondria R-HSA-111447
Programmed Cell Death R-HSA-5357801
Inflammasomes R-HSA-622312
Signaling by Nuclear Receptors R-HSA-9006931
Signal Transduction R-HSA-162582
Extra-nuclear estrogen signaling R-HSA-9009391
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Intrinsic Pathway for Apoptosis R-HSA-109606
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
The NLRP1 inflammasome R-HSA-844455
Signal Transduction R-HSA-162582
Inflammasomes R-HSA-622312
Extra-nuclear estrogen signaling R-HSA-9009391
ESR-mediated signaling R-HSA-8939211
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453
Programmed Cell Death R-HSA-5357801
Activation of BAD and translocation to mitochondria R-HSA-111447
Estrogen-dependent gene expression R-HSA-9018519
Immune System R-HSA-168256
Apoptosis R-HSA-109581
Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Activation of BH3-only proteins R-HSA-114452
Signaling by Nuclear Receptors R-HSA-9006931
Cytokine Signaling in Immune system R-HSA-1280215
Innate Immune System R-HSA-168249
ESR-mediated signaling R-HSA-8939211
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Extra-nuclear estrogen signaling R-HSA-9009391
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Activation of BAD and translocation to mitochondria R-HSA-111447
Estrogen-dependent gene expression R-HSA-9018519
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Nuclear Receptors R-HSA-9006931
Innate Immune System R-HSA-168249
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by Interleukins R-HSA-449147
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453
Programmed Cell Death R-HSA-5357801
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Apoptosis R-HSA-109581
The NLRP1 inflammasome R-HSA-844455
Inflammasomes R-HSA-622312
Activation of BH3-only proteins R-HSA-114452
Immune System R-HSA-168256
Activation of BH3-only proteins R-HSA-114452
Signaling by Nuclear Receptors R-HSA-9006931
The NLRP1 inflammasome R-HSA-844455
Intrinsic Pathway for Apoptosis R-HSA-109606
Estrogen-dependent gene expression R-HSA-9018519
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signal Transduction R-HSA-162582
Activation of BAD and translocation to mitochondria R-HSA-111447
Apoptosis R-HSA-109581
Innate Immune System R-HSA-168249
ESR-mediated signaling R-HSA-8939211
Immune System R-HSA-168256
Cytokine Signaling in Immune system R-HSA-1280215
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Signaling by Interleukins R-HSA-449147
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453
Extra-nuclear estrogen signaling R-HSA-9009391
Programmed Cell Death R-HSA-5357801
Inflammasomes R-HSA-622312
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Programmed Cell Death R-HSA-5357801
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Innate Immune System R-HSA-168249
Extra-nuclear estrogen signaling R-HSA-9009391
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
Apoptosis R-HSA-109581
Signaling by Nuclear Receptors R-HSA-9006931
Intrinsic Pathway for Apoptosis R-HSA-109606
The NLRP1 inflammasome R-HSA-844455
Estrogen-dependent gene expression R-HSA-9018519
Immune System R-HSA-168256
Activation of BH3-only proteins R-HSA-114452
ESR-mediated signaling R-HSA-8939211
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453
Inflammasomes R-HSA-622312
Activation of BAD and translocation to mitochondria R-HSA-111447
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807

Expression Atlas ENSG00000171791
LRG display in Ensembl gene LRG_1113
NCBI gene (formerly Entrezgene) 596
GeneCards 990
HGNC Symbol HGNC:990
MIM gene 151430
MIM morbid 151430
UniProtKB Gene Name P10415
WikiGene 596
Gene: APH1B
Ensembl ID : ENSG00000138613
Description: aph-1 homolog B, gamma-secretase subunit
Gene Synonyms: APH-1B,DKFZP564D0372,PSFL
5 APIs:
193 Possible Orthologues:

Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH4 R-HSA-9013694
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Axon guidance R-HSA-422475
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH2 R-HSA-1980145
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NRIF signals cell death from the nucleus R-HSA-205043
Regulated proteolysis of p75NTR R-HSA-193692
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
p75 NTR receptor-mediated signalling R-HSA-193704
Nervous system development R-HSA-9675108
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Nuclear signaling by ERBB4 R-HSA-1251985
Disease R-HSA-1643685
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH1 in Cancer R-HSA-2644603
Nuclear signaling by ERBB4 R-HSA-1251985
Signal Transduction R-HSA-162582
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH4 R-HSA-9013694
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p75 NTR receptor-mediated signalling R-HSA-193704
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Metabolism of proteins R-HSA-392499
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH2 R-HSA-1980145
Regulated proteolysis of p75NTR R-HSA-193692
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 R-HSA-1980143
NRIF signals cell death from the nucleus R-HSA-205043
Noncanonical activation of NOTCH3 R-HSA-9017802
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
Signaling by NOTCH2 R-HSA-1980145
Metabolism of proteins R-HSA-392499
Signaling by ERBB4 R-HSA-1236394
EPH-Ephrin signaling R-HSA-2682334
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Regulated proteolysis of p75NTR R-HSA-193692
Nervous system development R-HSA-9675108
Nuclear signaling by ERBB4 R-HSA-1251985
p75 NTR receptor-mediated signalling R-HSA-193704
NRIF signals cell death from the nucleus R-HSA-205043
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Disease R-HSA-1643685
Signaling by NOTCH1 R-HSA-1980143
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH4 R-HSA-9013694
Death Receptor Signaling R-HSA-73887
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH4 R-HSA-9013694
Regulated proteolysis of p75NTR R-HSA-193692
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Signaling by NOTCH2 R-HSA-1980145
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH3 R-HSA-9012852
Death Receptor Signaling R-HSA-73887
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NRIF signals cell death from the nucleus R-HSA-205043
Developmental Biology R-HSA-1266738
Amyloid fiber formation R-HSA-977225
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by ERBB4 R-HSA-1236394
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Nuclear signaling by ERBB4 R-HSA-1251985
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 R-HSA-1980143
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 R-HSA-1980143
p75 NTR receptor-mediated signalling R-HSA-193704
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Amyloid fiber formation R-HSA-977225
Nervous system development R-HSA-9675108
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nuclear signaling by ERBB4 R-HSA-1251985
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by ERBB4 R-HSA-1236394
EPH-Ephrin signaling R-HSA-2682334
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 in Cancer R-HSA-2644603
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signal Transduction R-HSA-162582
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH3 R-HSA-9012852
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH3 R-HSA-9012852
Nuclear signaling by ERBB4 R-HSA-1251985
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by ERBB4 R-HSA-1236394
Amyloid fiber formation R-HSA-977225
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 R-HSA-1980143
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Nervous system development R-HSA-9675108
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulated proteolysis of p75NTR R-HSA-193692
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH2 R-HSA-1980145
Axon guidance R-HSA-422475
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by ERBB4 R-HSA-1236394
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 in Cancer R-HSA-2644603
Death Receptor Signaling R-HSA-73887
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Metabolism of proteins R-HSA-392499
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH2 R-HSA-1980145
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH R-HSA-157118
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Amyloid fiber formation R-HSA-977225
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH2 R-HSA-1980145
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
Nuclear signaling by ERBB4 R-HSA-1251985
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 in Cancer R-HSA-2644603
Noncanonical activation of NOTCH3 R-HSA-9017802
Metabolism of proteins R-HSA-392499
Axon guidance R-HSA-422475
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Amyloid fiber formation R-HSA-977225
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
Regulated proteolysis of p75NTR R-HSA-193692
Amyloid fiber formation R-HSA-977225
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Regulated proteolysis of p75NTR R-HSA-193692
Noncanonical activation of NOTCH3 R-HSA-9017802
Signal Transduction R-HSA-162582
Nuclear signaling by ERBB4 R-HSA-1251985
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Axon guidance R-HSA-422475
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH3 R-HSA-9012852
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
Metabolism of proteins R-HSA-392499
NRIF signals cell death from the nucleus R-HSA-205043
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Signaling by NOTCH4 R-HSA-9013694
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH2 R-HSA-1980145

Expression Atlas ENSG00000138613
NCBI gene (formerly Entrezgene) 83464
GeneCards 24080
HGNC Symbol HGNC:24080
MIM gene 607630
UniProtKB Gene Name Q8WW43
WikiGene 83464