Gene: CFD
Ensembl ID : ENSG00000197766
Description: complement factor D
Gene Synonyms: ADN,DF,PFD
2 APIs:
134 Possible Orthologues:

Platelet degranulation R-HSA-114608
Alternative complement activation R-HSA-173736
Immune System R-HSA-168256
Initial triggering of complement R-HSA-166663
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Neutrophil degranulation R-HSA-6798695
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Innate Immune System R-HSA-168249
Complement cascade R-HSA-166658
Platelet degranulation R-HSA-114608
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Hemostasis R-HSA-109582
Neutrophil degranulation R-HSA-6798695
Alternative complement activation R-HSA-173736
Platelet activation, signaling and aggregation R-HSA-76002
Immune System R-HSA-168256
Initial triggering of complement R-HSA-166663
Innate Immune System R-HSA-168249
Complement cascade R-HSA-166658
Initial triggering of complement R-HSA-166663
Complement cascade R-HSA-166658
Neutrophil degranulation R-HSA-6798695
Alternative complement activation R-HSA-173736
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Platelet degranulation R-HSA-114608
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Initial triggering of complement R-HSA-166663
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Complement cascade R-HSA-166658
Hemostasis R-HSA-109582
Innate Immune System R-HSA-168249
Platelet degranulation R-HSA-114608
Alternative complement activation R-HSA-173736
Neutrophil degranulation R-HSA-6798695
Platelet activation, signaling and aggregation R-HSA-76002
Immune System R-HSA-168256
Initial triggering of complement R-HSA-166663
Innate Immune System R-HSA-168249
Platelet activation, signaling and aggregation R-HSA-76002
Immune System R-HSA-168256
Platelet degranulation R-HSA-114608
Hemostasis R-HSA-109582
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Complement cascade R-HSA-166658
Neutrophil degranulation R-HSA-6798695
Alternative complement activation R-HSA-173736
Hemostasis R-HSA-109582
Initial triggering of complement R-HSA-166663
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Innate Immune System R-HSA-168249
Alternative complement activation R-HSA-173736
Complement cascade R-HSA-166658
Immune System R-HSA-168256
Platelet degranulation R-HSA-114608
Platelet activation, signaling and aggregation R-HSA-76002
Neutrophil degranulation R-HSA-6798695
Hemostasis R-HSA-109582
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Initial triggering of complement R-HSA-166663
Alternative complement activation R-HSA-173736
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Complement cascade R-HSA-166658
Platelet degranulation R-HSA-114608
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Neutrophil degranulation R-HSA-6798695
Initial triggering of complement R-HSA-166663
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Alternative complement activation R-HSA-173736
Platelet degranulation R-HSA-114608
Immune System R-HSA-168256
Complement cascade R-HSA-166658
Platelet activation, signaling and aggregation R-HSA-76002
Innate Immune System R-HSA-168249
Innate Immune System R-HSA-168249
Platelet activation, signaling and aggregation R-HSA-76002
Platelet degranulation R-HSA-114608
Initial triggering of complement R-HSA-166663
Alternative complement activation R-HSA-173736
Immune System R-HSA-168256
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Complement cascade R-HSA-166658
Hemostasis R-HSA-109582
Neutrophil degranulation R-HSA-6798695

Expression Atlas ENSG00000197766
LRG display in Ensembl gene LRG_46
NCBI gene (formerly Entrezgene) 1675
GeneCards 2771
HGNC Symbol HGNC:2771
MIM gene 134350
MIM morbid 613912
UniProtKB Gene Name P00746
WikiGene 1675
Gene: PSMC2
Ensembl ID : ENSG00000161057
Description: proteasome 26S subunit, ATPase 2
Gene Synonyms: MSS1,NBLA10058,RPT1,S7
5 APIs:
222 Possible Orthologues:

Cell Cycle R-HSA-1640170
Metabolism of RNA R-HSA-8953854
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
Activation of NF-kappaB in B cells R-HSA-1169091
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
Gene expression (Transcription) R-HSA-74160
Vif-mediated degradation of APOBEC3G R-HSA-180585
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G2/M Transition R-HSA-69275
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Cellular response to chemical stress R-HSA-9711123
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Metaphase and Anaphase R-HSA-2555396
Neddylation R-HSA-8951664
Neutrophil degranulation R-HSA-6798695
Regulation of PTEN stability and activity R-HSA-8948751
Intracellular signaling by second messengers R-HSA-9006925
Downstream TCR signaling R-HSA-202424
M Phase R-HSA-68886
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Separation of Sister Chromatids R-HSA-2467813
Ub-specific processing proteases R-HSA-5689880
G1/S Transition R-HSA-69206
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'on' state R-HSA-5632684
Signal Transduction R-HSA-162582
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants are degraded by ERAD R-HSA-5362768
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Dependent G1 DNA Damage Response R-HSA-69563
FCERI mediated NF-kB activation R-HSA-2871837
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK1/MAPK3 signaling R-HSA-5684996
Vpu mediated degradation of CD4 R-HSA-180534
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
DNA Replication R-HSA-69306
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
C-type lectin receptors (CLRs) R-HSA-5621481
RNA Polymerase II Transcription R-HSA-73857
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of proteins R-HSA-392499
p53-Independent DNA Damage Response R-HSA-69610
Mitotic Anaphase R-HSA-68882
Antigen processing-Cross presentation R-HSA-1236975
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
TCR signaling R-HSA-202403
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PIP3 activates AKT signaling R-HSA-1257604
Cyclin E associated events during G1/S transition R-HSA-69202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cellular responses to stress R-HSA-2262752
Orc1 removal from chromatin R-HSA-68949
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle Checkpoints R-HSA-69620
Transport of small molecules R-HSA-382551
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
Cytokine Signaling in Immune system R-HSA-1280215
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Axon guidance R-HSA-422475
Deubiquitination R-HSA-5688426
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Metabolism R-HSA-1430728
Degradation of AXIN R-HSA-4641257
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle, Mitotic R-HSA-69278
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ER-Phagosome pathway R-HSA-1236974
Assembly of the pre-replicative complex R-HSA-68867
HIV Infection R-HSA-162906
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX3 R-HSA-8878159
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of RAS by GAPs R-HSA-5658442
MAPK family signaling cascades R-HSA-5683057
Class I MHC mediated antigen processing & presentation R-HSA-983169
Beta-catenin independent WNT signaling R-HSA-3858494
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle R-HSA-1640170
Metabolism of polyamines R-HSA-351202
ABC transporter disorders R-HSA-5619084
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Hedgehog ligand biogenesis R-HSA-5358346
Hh mutants abrogate ligand secretion R-HSA-5387390
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH4 R-HSA-9013694
Degradation of DVL R-HSA-4641258
Interleukin-1 family signaling R-HSA-446652
Signaling by WNT R-HSA-195721
Negative regulation of NOTCH4 signaling R-HSA-9604323
Stabilization of p53 R-HSA-69541
PTEN Regulation R-HSA-6807070
Signaling by ROBO receptors R-HSA-376176
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Developmental Biology R-HSA-1266738
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
Asymmetric localization of PCP proteins R-HSA-4608870
Immune System R-HSA-168256
Metabolism of amino acids and derivatives R-HSA-71291
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
RAF/MAP kinase cascade R-HSA-5673001
Regulation of Apoptosis R-HSA-169911
Switching of origins to a post-replicative state R-HSA-69052
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Nervous system development R-HSA-9675108
Synthesis of DNA R-HSA-69239
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M Checkpoints R-HSA-69481
Programmed Cell Death R-HSA-5357801
Adaptive Immune System R-HSA-1280218
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Nuclear events mediated by NFE2L2 R-HSA-9759194
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PCP/CE pathway R-HSA-4086400
Cellular response to hypoxia R-HSA-1234174
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
G2/M Transition R-HSA-69275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX3 R-HSA-8878159
PCP/CE pathway R-HSA-4086400
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX1 R-HSA-8878171
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK1/MAPK3 signaling R-HSA-5684996
NIK-->noncanonical NF-kB signaling R-HSA-5676590
PIP3 activates AKT signaling R-HSA-1257604
Neutrophil degranulation R-HSA-6798695
Assembly of the pre-replicative complex R-HSA-68867
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RAS by GAPs R-HSA-5658442
Signaling by WNT R-HSA-195721
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vpu mediated degradation of CD4 R-HSA-180534
Post-translational protein modification R-HSA-597592
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Hh mutants abrogate ligand secretion R-HSA-5387390
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
Programmed Cell Death R-HSA-5357801
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Interleukins R-HSA-449147
Ub-specific processing proteases R-HSA-5689880
CLEC7A (Dectin-1) signaling R-HSA-5607764
Nervous system development R-HSA-9675108
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Independent DNA Damage Response R-HSA-69610
Mitotic Metaphase and Anaphase R-HSA-2555396
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Infectious disease R-HSA-5663205
Metabolism of polyamines R-HSA-351202
Host Interactions of HIV factors R-HSA-162909
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'on' state R-HSA-5632684
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by NOTCH4 R-HSA-9013694
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
PTEN Regulation R-HSA-6807070
Regulation of mitotic cell cycle R-HSA-453276
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
FCERI mediated NF-kB activation R-HSA-2871837
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Dependent G1 DNA Damage Response R-HSA-69563
Orc1 removal from chromatin R-HSA-68949
Gene expression (Transcription) R-HSA-74160
ER-Phagosome pathway R-HSA-1236974
HIV Infection R-HSA-162906
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Synthesis of DNA R-HSA-69239
Mitotic G2-G2/M phases R-HSA-453274
Signal Transduction R-HSA-162582
Hh mutants are degraded by ERAD R-HSA-5362768
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Cellular response to hypoxia R-HSA-1234174
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
Regulation of Apoptosis R-HSA-169911
ABC transporter disorders R-HSA-5619084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Hedgehog R-HSA-5358351
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
Developmental Biology R-HSA-1266738
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Stabilization of p53 R-HSA-69541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI1 by the proteasome R-HSA-5610780
DNA Replication R-HSA-69306
Regulation of RUNX2 expression and activity R-HSA-8939902
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
Transport of small molecules R-HSA-382551
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of amino acids and derivatives R-HSA-71291
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX2 R-HSA-8878166
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of RNA R-HSA-8953854
RNA Polymerase II Transcription R-HSA-73857
Hedgehog ligand biogenesis R-HSA-5358346
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
Regulation of PTEN stability and activity R-HSA-8948751
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'off' state R-HSA-5610787
Innate Immune System R-HSA-168249
Asymmetric localization of PCP proteins R-HSA-4608870
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic Anaphase R-HSA-68882
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
G2/M Checkpoints R-HSA-69481
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Regulation of mitotic cell cycle R-HSA-453276
Neddylation R-HSA-8951664
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Synthesis of DNA R-HSA-69239
Post-translational protein modification R-HSA-597592
Cell Cycle, Mitotic R-HSA-69278
p53-Independent DNA Damage Response R-HSA-69610
Cyclin E associated events during G1/S transition R-HSA-69202
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 signaling R-HSA-9020702
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vif-mediated degradation of APOBEC3G R-HSA-180585
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by NOTCH4 R-HSA-9013694
Degradation of DVL R-HSA-4641258
Switching of origins to a post-replicative state R-HSA-69052
Cellular responses to stress R-HSA-2262752
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
UCH proteinases R-HSA-5689603
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX2 expression and activity R-HSA-8939902
PIP3 activates AKT signaling R-HSA-1257604
Hh mutants are degraded by ERAD R-HSA-5362768
Beta-catenin independent WNT signaling R-HSA-3858494
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1/S Transition R-HSA-69206
Transcriptional regulation by RUNX2 R-HSA-8878166
DNA Replication Pre-Initiation R-HSA-69002
PCP/CE pathway R-HSA-4086400
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic G1 phase and G1/S transition R-HSA-453279
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
S Phase R-HSA-69242
Developmental Biology R-HSA-1266738
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of polyamines R-HSA-351202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream TCR signaling R-HSA-202424
Hedgehog ligand biogenesis R-HSA-5358346
DNA Replication R-HSA-69306
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RAS by GAPs R-HSA-5658442
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Separation of Sister Chromatids R-HSA-2467813
G2/M Checkpoints R-HSA-69481
Degradation of AXIN R-HSA-4641257
Interleukin-1 family signaling R-HSA-446652
Ub-specific processing proteases R-HSA-5689880
Regulation of PTEN stability and activity R-HSA-8948751
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by NOTCH R-HSA-157118
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activation of NF-kappaB in B cells R-HSA-1169091
ABC transporter disorders R-HSA-5619084
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
Transport of small molecules R-HSA-382551
MAPK6/MAPK4 signaling R-HSA-5687128
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'off' state R-HSA-5610787
PTEN Regulation R-HSA-6807070
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX3 R-HSA-8878159
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of NOTCH4 signaling R-HSA-9604323
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by Hedgehog R-HSA-5358351
G1/S DNA Damage Checkpoints R-HSA-69615
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
MAPK family signaling cascades R-HSA-5683057
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1 DNA Damage Response R-HSA-69563
RAF/MAP kinase cascade R-HSA-5673001
Host Interactions of HIV factors R-HSA-162909
Vpu mediated degradation of CD4 R-HSA-180534
Programmed Cell Death R-HSA-5357801
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
M Phase R-HSA-68886
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
FCERI mediated NF-kB activation R-HSA-2871837
Stabilization of p53 R-HSA-69541
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
TCR signaling R-HSA-202403
Metabolism R-HSA-1430728
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
Regulation of Apoptosis R-HSA-169911
Disease R-HSA-1643685
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing-Cross presentation R-HSA-1236975
Disorders of transmembrane transporters R-HSA-5619115
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Gene expression (Transcription) R-HSA-74160
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Anaphase R-HSA-68882
Deubiquitination R-HSA-5688426
Signaling by Interleukins R-HSA-449147
Metabolism of amino acids and derivatives R-HSA-71291
ABC-family proteins mediated transport R-HSA-382556
Orc1 removal from chromatin R-HSA-68949
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of proteins R-HSA-392499
Assembly of the pre-replicative complex R-HSA-68867
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'off' state R-HSA-5610787
Cellular response to hypoxia R-HSA-1234174
DNA Replication R-HSA-69306
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RAS by GAPs R-HSA-5658442
Axon guidance R-HSA-422475
ABC transporter disorders R-HSA-5619084
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 signaling R-HSA-9020702
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism R-HSA-1430728
Metabolism of polyamines R-HSA-351202
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog ligand biogenesis R-HSA-5358346
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 family signaling R-HSA-446652
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
MAPK family signaling cascades R-HSA-5683057
Apoptosis R-HSA-109581
Hh mutants abrogate ligand secretion R-HSA-5387390
Infectious disease R-HSA-5663205
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX2 R-HSA-8878166
Orc1 removal from chromatin R-HSA-68949
Vpu mediated degradation of CD4 R-HSA-180534
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI2 by the proteasome R-HSA-5610783
UCH proteinases R-HSA-5689603
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PTEN Regulation R-HSA-6807070
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Beta-catenin independent WNT signaling R-HSA-3858494
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Class I MHC mediated antigen processing & presentation R-HSA-983169
G2/M Transition R-HSA-69275
M Phase R-HSA-68886
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog 'on' state R-HSA-5632684
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of RNA R-HSA-8953854
Degradation of beta-catenin by the destruction complex R-HSA-195253
Activation of NF-kappaB in B cells R-HSA-1169091
G1/S Transition R-HSA-69206
Post-translational protein modification R-HSA-597592
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Assembly of the pre-replicative complex R-HSA-68867
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Downstream TCR signaling R-HSA-202424
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cell Cycle Checkpoints R-HSA-69620
Degradation of AXIN R-HSA-4641257
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Programmed Cell Death R-HSA-5357801
p53-Independent DNA Damage Response R-HSA-69610
Signaling by WNT R-HSA-195721
Synthesis of DNA R-HSA-69239
ABC-family proteins mediated transport R-HSA-382556
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
HIV Infection R-HSA-162906
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Dependent G1 DNA Damage Response R-HSA-69563
ER-Phagosome pathway R-HSA-1236974
Transport of small molecules R-HSA-382551
MAPK1/MAPK3 signaling R-HSA-5684996
TCF dependent signaling in response to WNT R-HSA-201681
Generic Transcription Pathway R-HSA-212436
Degradation of DVL R-HSA-4641258
Signaling by Hedgehog R-HSA-5358351
Vif-mediated degradation of APOBEC3G R-HSA-180585
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle, Mitotic R-HSA-69278
Host Interactions of HIV factors R-HSA-162909
PCP/CE pathway R-HSA-4086400
DNA Replication Pre-Initiation R-HSA-69002
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Deubiquitination R-HSA-5688426
Defective CFTR causes cystic fibrosis R-HSA-5678895
PIP3 activates AKT signaling R-HSA-1257604
Mitotic Metaphase and Anaphase R-HSA-2555396
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Neutrophil degranulation R-HSA-6798695
Signaling by the B Cell Receptor (BCR) R-HSA-983705
C-type lectin receptors (CLRs) R-HSA-5621481
Antigen processing-Cross presentation R-HSA-1236975
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle R-HSA-1640170
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
FCERI mediated NF-kB activation R-HSA-2871837
G2/M Checkpoints R-HSA-69481
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Degradation of GLI1 by the proteasome R-HSA-5610780
Immune System R-HSA-168256
Regulation of PTEN stability and activity R-HSA-8948751
Disorders of transmembrane transporters R-HSA-5619115
Cyclin E associated events during G1/S transition R-HSA-69202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic Anaphase R-HSA-68882
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by NOTCH4 R-HSA-9013694
Gene expression (Transcription) R-HSA-74160
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Generic Transcription Pathway R-HSA-212436
ABC-family proteins mediated transport R-HSA-382556
Separation of Sister Chromatids R-HSA-2467813
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
DNA Replication Pre-Initiation R-HSA-69002
Mitotic Metaphase and Anaphase R-HSA-2555396
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ub-specific processing proteases R-HSA-5689880
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disease R-HSA-1643685
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Switching of origins to a post-replicative state R-HSA-69052
MAPK family signaling cascades R-HSA-5683057
Degradation of AXIN R-HSA-4641257
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of proteins R-HSA-392499
Neutrophil degranulation R-HSA-6798695
ABC transporter disorders R-HSA-5619084
Orc1 removal from chromatin R-HSA-68949
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
UCH proteinases R-HSA-5689603
DNA Replication R-HSA-69306
Gene expression (Transcription) R-HSA-74160
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stimuli R-HSA-8953897
Asymmetric localization of PCP proteins R-HSA-4608870
Immune System R-HSA-168256
Cell Cycle, Mitotic R-HSA-69278
TCR signaling R-HSA-202403
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PCP/CE pathway R-HSA-4086400
Metabolism of polyamines R-HSA-351202
Mitotic Anaphase R-HSA-68882
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signal Transduction R-HSA-162582
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Infectious disease R-HSA-5663205
HIV Infection R-HSA-162906
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Downstream TCR signaling R-HSA-202424
Vpu mediated degradation of CD4 R-HSA-180534
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Apoptosis R-HSA-109581
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
KEAP1-NFE2L2 pathway R-HSA-9755511
G2/M Transition R-HSA-69275
Class I MHC mediated antigen processing & presentation R-HSA-983169
RNA Polymerase II Transcription R-HSA-73857
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
PTEN Regulation R-HSA-6807070
Beta-catenin independent WNT signaling R-HSA-3858494
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of Apoptosis R-HSA-169911
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Independent DNA Damage Response R-HSA-69610
Regulation of PTEN stability and activity R-HSA-8948751
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH4 R-HSA-9013694
Nervous system development R-HSA-9675108
Cell Cycle R-HSA-1640170
Cellular response to hypoxia R-HSA-1234174
Cytokine Signaling in Immune system R-HSA-1280215
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RAS by GAPs R-HSA-5658442
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX2 expression and activity R-HSA-8939902
FCERI mediated NF-kB activation R-HSA-2871837
Axon guidance R-HSA-422475
Hh mutants are degraded by ERAD R-HSA-5362768
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PIP3 activates AKT signaling R-HSA-1257604
Disorders of transmembrane transporters R-HSA-5619115
Transcriptional regulation by RUNX1 R-HSA-8878171
Adaptive Immune System R-HSA-1280218
M Phase R-HSA-68886
Cyclin E associated events during G1/S transition R-HSA-69202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to chemical stress R-HSA-9711123
Programmed Cell Death R-HSA-5357801
Signaling by WNT R-HSA-195721
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transport of small molecules R-HSA-382551
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
Post-translational protein modification R-HSA-597592
S Phase R-HSA-69242
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Interleukin-1 family signaling R-HSA-446652
Signaling by Interleukins R-HSA-449147
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
Deubiquitination R-HSA-5688426
Mitotic G2-G2/M phases R-HSA-453274
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Disorders of transmembrane transporters R-HSA-5619115
Transport of small molecules R-HSA-382551
Degradation of AXIN R-HSA-4641257
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism R-HSA-1430728
Orc1 removal from chromatin R-HSA-68949
Cell Cycle Checkpoints R-HSA-69620
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Intracellular signaling by second messengers R-HSA-9006925
S Phase R-HSA-69242
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of polyamines R-HSA-351202
Programmed Cell Death R-HSA-5357801
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
HIV Infection R-HSA-162906
Degradation of beta-catenin by the destruction complex R-HSA-195253
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX3 expression and activity R-HSA-8941858
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by NOTCH R-HSA-157118
RAF/MAP kinase cascade R-HSA-5673001
Nuclear events mediated by NFE2L2 R-HSA-9759194
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TCR signaling R-HSA-202403
Interleukin-1 family signaling R-HSA-446652
PTEN Regulation R-HSA-6807070
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants are degraded by ERAD R-HSA-5362768
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Infectious disease R-HSA-5663205
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Interleukin-1 signaling R-HSA-9020702
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Generic Transcription Pathway R-HSA-212436
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX2 R-HSA-8878166
Deubiquitination R-HSA-5688426
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular responses to stress R-HSA-2262752
Regulation of RAS by GAPs R-HSA-5658442
Developmental Biology R-HSA-1266738
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
M Phase R-HSA-68886
RNA Polymerase II Transcription R-HSA-73857
Regulation of mitotic cell cycle R-HSA-453276
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Hedgehog R-HSA-5358351
Antigen processing-Cross presentation R-HSA-1236975
ABC transporter disorders R-HSA-5619084
Ub-specific processing proteases R-HSA-5689880
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Apoptosis R-HSA-109581
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Innate Immune System R-HSA-168249
Separation of Sister Chromatids R-HSA-2467813
Regulation of RUNX2 expression and activity R-HSA-8939902
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
DNA Replication Pre-Initiation R-HSA-69002
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of GLI1 by the proteasome R-HSA-5610780
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
ABC-family proteins mediated transport R-HSA-382556
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to hypoxia R-HSA-1234174
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of proteins R-HSA-392499
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Negative regulation of NOTCH4 signaling R-HSA-9604323
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Immune System R-HSA-168256
Mitotic G1 phase and G1/S transition R-HSA-453279
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog 'off' state R-HSA-5610787
G1/S DNA Damage Checkpoints R-HSA-69615
TCF dependent signaling in response to WNT R-HSA-201681
ER-Phagosome pathway R-HSA-1236974
UCH proteinases R-HSA-5689603
Mitotic Metaphase and Anaphase R-HSA-2555396
G1/S Transition R-HSA-69206
Neutrophil degranulation R-HSA-6798695
Stabilization of p53 R-HSA-69541
Degradation of DVL R-HSA-4641258
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Class I MHC mediated antigen processing & presentation R-HSA-983169
Gene expression (Transcription) R-HSA-74160
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Activation of NF-kappaB in B cells R-HSA-1169091
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Transition R-HSA-69275
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle R-HSA-1640170
Hedgehog 'on' state R-HSA-5632684
Neddylation R-HSA-8951664
Adaptive Immune System R-HSA-1280218
KEAP1-NFE2L2 pathway R-HSA-9755511
PIP3 activates AKT signaling R-HSA-1257604
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of GLI2 by the proteasome R-HSA-5610783
Assembly of the pre-replicative complex R-HSA-68867
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
Signaling by NOTCH4 R-HSA-9013694
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G1/S Transition R-HSA-69206
Metabolism of proteins R-HSA-392499
Cell Cycle R-HSA-1640170
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ER-Phagosome pathway R-HSA-1236974
Stabilization of p53 R-HSA-69541
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stress R-HSA-2262752
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Infectious disease R-HSA-5663205
Signaling by Hedgehog R-HSA-5358351
Adaptive Immune System R-HSA-1280218
Programmed Cell Death R-HSA-5357801
UCH proteinases R-HSA-5689603
Disease R-HSA-1643685
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH4 R-HSA-9013694
Cellular response to hypoxia R-HSA-1234174
ABC-family proteins mediated transport R-HSA-382556
KEAP1-NFE2L2 pathway R-HSA-9755511
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
G2/M Transition R-HSA-69275
Neddylation R-HSA-8951664
PCP/CE pathway R-HSA-4086400
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Deubiquitination R-HSA-5688426
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK family signaling cascades R-HSA-5683057
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Regulation of mitotic cell cycle R-HSA-453276
Vpu mediated degradation of CD4 R-HSA-180534
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Axon guidance R-HSA-422475
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle, Mitotic R-HSA-69278
Neutrophil degranulation R-HSA-6798695
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Downstream TCR signaling R-HSA-202424
Mitotic Anaphase R-HSA-68882
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants abrogate ligand secretion R-HSA-5387390
Transcriptional regulation by RUNX2 R-HSA-8878166
CLEC7A (Dectin-1) signaling R-HSA-5607764
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
TCR signaling R-HSA-202403
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of PTEN stability and activity R-HSA-8948751
Asymmetric localization of PCP proteins R-HSA-4608870
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
HIV Infection R-HSA-162906
Nuclear events mediated by NFE2L2 R-HSA-9759194
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Innate Immune System R-HSA-168249
Synthesis of DNA R-HSA-69239
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Mitotic G2-G2/M phases R-HSA-453274
Generic Transcription Pathway R-HSA-212436
Separation of Sister Chromatids R-HSA-2467813
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
C-type lectin receptors (CLRs) R-HSA-5621481
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transport of small molecules R-HSA-382551
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog 'on' state R-HSA-5632684
Disorders of transmembrane transporters R-HSA-5619115
Degradation of DVL R-HSA-4641258
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Orc1 removal from chromatin R-HSA-68949
Post-translational protein modification R-HSA-597592
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
Ub-specific processing proteases R-HSA-5689880
Degradation of AXIN R-HSA-4641257
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of Apoptosis R-HSA-169911
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Assembly of the pre-replicative complex R-HSA-68867
MAPK6/MAPK4 signaling R-HSA-5687128
Host Interactions of HIV factors R-HSA-162909
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of RNA R-HSA-8953854
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH R-HSA-157118
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX2 expression and activity R-HSA-8939902
Signal Transduction R-HSA-162582
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Interleukins R-HSA-449147
Interleukin-1 family signaling R-HSA-446652
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Apoptosis R-HSA-109581
Signaling by ROBO receptors R-HSA-376176
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
DNA Replication R-HSA-69306
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
G1/S DNA Damage Checkpoints R-HSA-69615
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 family signaling R-HSA-446652
Mitotic Anaphase R-HSA-68882
TCR signaling R-HSA-202403
Signaling by NOTCH4 R-HSA-9013694
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants are degraded by ERAD R-HSA-5362768
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
Intracellular signaling by second messengers R-HSA-9006925
Cellular responses to stimuli R-HSA-8953897
Asymmetric localization of PCP proteins R-HSA-4608870
Adaptive Immune System R-HSA-1280218
Transport of small molecules R-HSA-382551
Synthesis of DNA R-HSA-69239
Metabolism of amino acids and derivatives R-HSA-71291
M Phase R-HSA-68886
Deubiquitination R-HSA-5688426
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent DNA Damage Response R-HSA-69610
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog 'off' state R-HSA-5610787
ABC-family proteins mediated transport R-HSA-382556
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of PTEN stability and activity R-HSA-8948751
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Signaling by Hedgehog R-HSA-5358351
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of RNA R-HSA-8953854
Degradation of AXIN R-HSA-4641257
KEAP1-NFE2L2 pathway R-HSA-9755511
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Transcriptional regulation by RUNX2 R-HSA-8878166
Vpu mediated degradation of CD4 R-HSA-180534
Disorders of transmembrane transporters R-HSA-5619115
Gene expression (Transcription) R-HSA-74160
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of Apoptosis R-HSA-169911
Generic Transcription Pathway R-HSA-212436
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI2 by the proteasome R-HSA-5610783
DNA Replication R-HSA-69306
Switching of origins to a post-replicative state R-HSA-69052
Ub-specific processing proteases R-HSA-5689880
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Host Interactions of HIV factors R-HSA-162909
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
S Phase R-HSA-69242
G2/M Checkpoints R-HSA-69481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic Metaphase and Anaphase R-HSA-2555396
Assembly of the pre-replicative complex R-HSA-68867
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX1 R-HSA-8878171
NIK-->noncanonical NF-kB signaling R-HSA-5676590
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cell Cycle, Mitotic R-HSA-69278
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of RAS by GAPs R-HSA-5658442
Cellular response to chemical stress R-HSA-9711123
UCH proteinases R-HSA-5689603
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Interleukin-1 signaling R-HSA-9020702
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by WNT R-HSA-195721
Defective CFTR causes cystic fibrosis R-HSA-5678895
G2/M Transition R-HSA-69275
Degradation of DVL R-HSA-4641258
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G2-G2/M phases R-HSA-453274
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle Checkpoints R-HSA-69620
Neutrophil degranulation R-HSA-6798695
Metabolism of proteins R-HSA-392499
Signaling by ROBO receptors R-HSA-376176
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Axon guidance R-HSA-422475
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH R-HSA-157118
G1/S DNA Damage Checkpoints R-HSA-69615
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism R-HSA-1430728
Nervous system development R-HSA-9675108
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle R-HSA-1640170
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
Signaling by Interleukins R-HSA-449147
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream TCR signaling R-HSA-202424
HIV Infection R-HSA-162906
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
RAF/MAP kinase cascade R-HSA-5673001
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog 'on' state R-HSA-5632684
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Stabilization of p53 R-HSA-69541
Metabolism of polyamines R-HSA-351202
Signal Transduction R-HSA-162582
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
PCP/CE pathway R-HSA-4086400
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S Transition R-HSA-69206
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
DNA Replication Pre-Initiation R-HSA-69002
Developmental Biology R-HSA-1266738
Apoptosis R-HSA-109581
Negative regulation of NOTCH4 signaling R-HSA-9604323
Immune System R-HSA-168256
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
Infectious disease R-HSA-5663205
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of NF-kappaB in B cells R-HSA-1169091
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signal Transduction R-HSA-162582
Cellular response to chemical stress R-HSA-9711123
G1/S DNA Damage Checkpoints R-HSA-69615
Antigen processing-Cross presentation R-HSA-1236975
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of polyamines R-HSA-351202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
DNA Replication R-HSA-69306
Transcriptional regulation by RUNX3 R-HSA-8878159
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Synthesis of DNA R-HSA-69239
Cellular responses to stress R-HSA-2262752
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Adaptive Immune System R-HSA-1280218
G2/M Checkpoints R-HSA-69481
Neddylation R-HSA-8951664
Hh mutants are degraded by ERAD R-HSA-5362768
UCH proteinases R-HSA-5689603
Ub-specific processing proteases R-HSA-5689880
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Vpu mediated degradation of CD4 R-HSA-180534
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI1 by the proteasome R-HSA-5610780
Cell Cycle, Mitotic R-HSA-69278
Degradation of DVL R-HSA-4641258
Signaling by WNT R-HSA-195721
Signaling by ROBO receptors R-HSA-376176
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
M Phase R-HSA-68886
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G2/M Transition R-HSA-69275
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of amino acids and derivatives R-HSA-71291
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 family signaling R-HSA-446652
KEAP1-NFE2L2 pathway R-HSA-9755511
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants abrogate ligand secretion R-HSA-5387390
Separation of Sister Chromatids R-HSA-2467813
Activation of NF-kappaB in B cells R-HSA-1169091
Programmed Cell Death R-HSA-5357801
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Hedgehog ligand biogenesis R-HSA-5358346
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 signaling R-HSA-9020702
Cell Cycle R-HSA-1640170
HIV Infection R-HSA-162906
Mitotic G2-G2/M phases R-HSA-453274
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
FCERI mediated NF-kB activation R-HSA-2871837
Developmental Biology R-HSA-1266738
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hedgehog 'on' state R-HSA-5632684
Metabolism of proteins R-HSA-392499
TCF dependent signaling in response to WNT R-HSA-201681
TCR signaling R-HSA-202403
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Anaphase R-HSA-68882
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Orc1 removal from chromatin R-HSA-68949
Axon guidance R-HSA-422475
Regulation of mitotic cell cycle R-HSA-453276
Switching of origins to a post-replicative state R-HSA-69052
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stimuli R-HSA-8953897
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of RNA R-HSA-8953854
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Independent DNA Damage Response R-HSA-69610
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
PIP3 activates AKT signaling R-HSA-1257604
Neutrophil degranulation R-HSA-6798695
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Host Interactions of HIV factors R-HSA-162909
Defective CFTR causes cystic fibrosis R-HSA-5678895
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
DNA Replication Pre-Initiation R-HSA-69002
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G1/S Transition R-HSA-69206
Regulation of RUNX2 expression and activity R-HSA-8939902
ABC transporter disorders R-HSA-5619084
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
C-type lectin receptors (CLRs) R-HSA-5621481
Transport of small molecules R-HSA-382551
MAPK family signaling cascades R-HSA-5683057
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to hypoxia R-HSA-1234174
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of Apoptosis R-HSA-169911
Disease R-HSA-1643685
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by NOTCH4 R-HSA-9013694
Signaling by Hedgehog R-HSA-5358351
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of RUNX3 expression and activity R-HSA-8941858
Beta-catenin independent WNT signaling R-HSA-3858494
Post-translational protein modification R-HSA-597592
Cell Cycle Checkpoints R-HSA-69620
Assembly of the pre-replicative complex R-HSA-68867
Hedgehog 'off' state R-HSA-5610787
Metabolism R-HSA-1430728
Infectious disease R-HSA-5663205
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
Regulation of RAS by GAPs R-HSA-5658442
Programmed Cell Death R-HSA-5357801
Neutrophil degranulation R-HSA-6798695
Cell Cycle, Mitotic R-HSA-69278
Metabolism of RNA R-HSA-8953854
Signaling by WNT R-HSA-195721
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Orc1 removal from chromatin R-HSA-68949
Assembly of the pre-replicative complex R-HSA-68867
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
M Phase R-HSA-68886
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of mitotic cell cycle R-HSA-453276
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ROBO receptors R-HSA-376176
Host Interactions of HIV factors R-HSA-162909
Ub-specific processing proteases R-HSA-5689880
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC transporter disorders R-HSA-5619084
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of beta-catenin by the destruction complex R-HSA-195253
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Apoptosis R-HSA-109581
Hedgehog 'on' state R-HSA-5632684
TCF dependent signaling in response to WNT R-HSA-201681
Synthesis of DNA R-HSA-69239
UCH proteinases R-HSA-5689603
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH R-HSA-157118
FCERI mediated NF-kB activation R-HSA-2871837
PTEN Regulation R-HSA-6807070
Disorders of transmembrane transporters R-HSA-5619115
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of AXIN R-HSA-4641257
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Class I MHC mediated antigen processing & presentation R-HSA-983169
C-type lectin receptors (CLRs) R-HSA-5621481
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream TCR signaling R-HSA-202424
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Checkpoints R-HSA-69481
Hh mutants are degraded by ERAD R-HSA-5362768
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to chemical stress R-HSA-9711123
Cell Cycle Checkpoints R-HSA-69620
Antigen processing-Cross presentation R-HSA-1236975
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
PIP3 activates AKT signaling R-HSA-1257604
ER-Phagosome pathway R-HSA-1236974
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Separation of Sister Chromatids R-HSA-2467813
DNA Replication R-HSA-69306
Nervous system development R-HSA-9675108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Mitotic G2-G2/M phases R-HSA-453274
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin E associated events during G1/S transition R-HSA-69202
Negative regulation of NOTCH4 signaling R-HSA-9604323
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic Anaphase R-HSA-68882
ABC-family proteins mediated transport R-HSA-382556
Regulation of Apoptosis R-HSA-169911
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle R-HSA-1640170
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
CLEC7A (Dectin-1) signaling R-HSA-5607764
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of DVL R-HSA-4641258
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by NOTCH4 R-HSA-9013694
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PCP/CE pathway R-HSA-4086400
Axon guidance R-HSA-422475
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Stabilization of p53 R-HSA-69541
Neddylation R-HSA-8951664
Regulation of RUNX3 expression and activity R-HSA-8941858
Defective CFTR causes cystic fibrosis R-HSA-5678895
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Interleukin-1 family signaling R-HSA-446652
Developmental Biology R-HSA-1266738
Signaling by Hedgehog R-HSA-5358351
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of polyamines R-HSA-351202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transport of small molecules R-HSA-382551
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S Transition R-HSA-69206
Degradation of GLI2 by the proteasome R-HSA-5610783
G2/M Transition R-HSA-69275
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
DNA Replication Pre-Initiation R-HSA-69002
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Programmed Cell Death R-HSA-5357801
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of Apoptosis R-HSA-169911
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX3 R-HSA-8878159
Interleukin-1 family signaling R-HSA-446652
MAPK family signaling cascades R-HSA-5683057
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Assembly of the pre-replicative complex R-HSA-68867
Mitotic G1 phase and G1/S transition R-HSA-453279
Post-translational protein modification R-HSA-597592
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
UCH proteinases R-HSA-5689603
Signal Transduction R-HSA-162582
FCERI mediated NF-kB activation R-HSA-2871837
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
Antigen processing-Cross presentation R-HSA-1236975
ABC transporter disorders R-HSA-5619084
Metabolism of amino acids and derivatives R-HSA-71291
Deubiquitination R-HSA-5688426
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Separation of Sister Chromatids R-HSA-2467813
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Stabilization of p53 R-HSA-69541
Signaling by NOTCH4 R-HSA-9013694
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle Checkpoints R-HSA-69620
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
Regulation of RAS by GAPs R-HSA-5658442
Host Interactions of HIV factors R-HSA-162909
Switching of origins to a post-replicative state R-HSA-69052
PIP3 activates AKT signaling R-HSA-1257604
M Phase R-HSA-68886
Nuclear events mediated by NFE2L2 R-HSA-9759194
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
Degradation of AXIN R-HSA-4641257
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK1/MAPK3 signaling R-HSA-5684996
DNA Replication Pre-Initiation R-HSA-69002
Immune System R-HSA-168256
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic G2-G2/M phases R-HSA-453274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to hypoxia R-HSA-1234174
Metabolism of RNA R-HSA-8953854
Signaling by WNT R-HSA-195721
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Activation of NF-kappaB in B cells R-HSA-1169091
Transport of small molecules R-HSA-382551
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Disorders of transmembrane transporters R-HSA-5619115
ABC-family proteins mediated transport R-HSA-382556
HIV Infection R-HSA-162906
Adaptive Immune System R-HSA-1280218
RAF/MAP kinase cascade R-HSA-5673001
Mitotic Anaphase R-HSA-68882
G2/M Transition R-HSA-69275
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
p53-Independent DNA Damage Response R-HSA-69610
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
C-type lectin receptors (CLRs) R-HSA-5621481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
TCR signaling R-HSA-202403
Neutrophil degranulation R-HSA-6798695
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PTEN Regulation R-HSA-6807070
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Infectious disease R-HSA-5663205
Neddylation R-HSA-8951664
Signaling by Hedgehog R-HSA-5358351
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mitotic cell cycle R-HSA-453276
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic Metaphase and Anaphase R-HSA-2555396
Class I MHC mediated antigen processing & presentation R-HSA-983169
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of beta-catenin by the destruction complex R-HSA-195253
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cytokine Signaling in Immune system R-HSA-1280215
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
G2/M Checkpoints R-HSA-69481
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Synthesis of DNA R-HSA-69239
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Metabolism of polyamines R-HSA-351202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'on' state R-HSA-5632684

Expression Atlas ENSG00000161057
NCBI gene (formerly Entrezgene) 5701
GeneCards 9548
HGNC Symbol HGNC:9548
MIM gene 154365
UniProtKB Gene Name P35998
WikiGene 5701
Gene: BACE1
Ensembl ID : ENSG00000186318
Description: beta-secretase 1
Gene Synonyms: BACE
4 APIs:
220 Possible Orthologues:

Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225

Expression Atlas ENSG00000186318
NCBI gene (formerly Entrezgene) 23621
GeneCards 933
HGNC Symbol HGNC:933
MIM gene 604252
UniProtKB Gene Name U3KPS1
WikiGene 23621
Gene: PSMB11
Ensembl ID : ENSG00000222028
Description: proteasome subunit beta 11
Gene Synonyms: BETA5T
6 APIs:
228 Possible Orthologues:

Cytokine Signaling in Immune system R-HSA-1280215
TCR signaling R-HSA-202403
Signaling by Interleukins R-HSA-449147
Programmed Cell Death R-HSA-5357801
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G2/M Transition R-HSA-69275
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism R-HSA-1430728
ER-Phagosome pathway R-HSA-1236974
ABC transporter disorders R-HSA-5619084
S Phase R-HSA-69242
Hedgehog 'off' state R-HSA-5610787
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of polyamines R-HSA-351202
Separation of Sister Chromatids R-HSA-2467813
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
p53-Independent DNA Damage Response R-HSA-69610
ABC-family proteins mediated transport R-HSA-382556
Innate Immune System R-HSA-168249
Regulation of mitotic cell cycle R-HSA-453276
Deubiquitination R-HSA-5688426
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic G2-G2/M phases R-HSA-453274
Immune System R-HSA-168256
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stimuli R-HSA-8953897
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX2 R-HSA-8878166
Post-translational protein modification R-HSA-597592
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI2 by the proteasome R-HSA-5610783
RAF/MAP kinase cascade R-HSA-5673001
Degradation of AXIN R-HSA-4641257
Axon guidance R-HSA-422475
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle, Mitotic R-HSA-69278
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Dependent G1 DNA Damage Response R-HSA-69563
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Switching of origins to a post-replicative state R-HSA-69052
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hedgehog 'on' state R-HSA-5632684
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of DVL R-HSA-4641258
Cell Cycle R-HSA-1640170
Mitotic Anaphase R-HSA-68882
Cellular response to chemical stress R-HSA-9711123
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
HIV Infection R-HSA-162906
Hh mutants are degraded by ERAD R-HSA-5362768
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of NF-kappaB in B cells R-HSA-1169091
Ub-specific processing proteases R-HSA-5689880
Synthesis of DNA R-HSA-69239
Transport of small molecules R-HSA-382551
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 signaling R-HSA-9020702
Downstream TCR signaling R-HSA-202424
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
Regulation of Apoptosis R-HSA-169911
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI1 by the proteasome R-HSA-5610780
Antigen processing-Cross presentation R-HSA-1236975
Signaling by WNT R-HSA-195721
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of PTEN stability and activity R-HSA-8948751
Infectious disease R-HSA-5663205
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
C-type lectin receptors (CLRs) R-HSA-5621481
Apoptosis R-HSA-109581
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hh mutants abrogate ligand secretion R-HSA-5387390
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX1 R-HSA-8878171
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of beta-catenin by the destruction complex R-HSA-195253
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Interleukin-1 family signaling R-HSA-446652
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G1/S DNA Damage Checkpoints R-HSA-69615
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular response to hypoxia R-HSA-1234174
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Hedgehog R-HSA-5358351
Separation of Sister Chromatids R-HSA-2467813
Metabolism of RNA R-HSA-8953854
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Metabolism R-HSA-1430728
Programmed Cell Death R-HSA-5357801
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of AXIN R-HSA-4641257
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of polyamines R-HSA-351202
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
Beta-catenin independent WNT signaling R-HSA-3858494
ER-Phagosome pathway R-HSA-1236974
Hedgehog ligand biogenesis R-HSA-5358346
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
ABC-family proteins mediated transport R-HSA-382556
MAPK family signaling cascades R-HSA-5683057
Post-translational protein modification R-HSA-597592
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of Apoptosis R-HSA-169911
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Hedgehog R-HSA-5358351
G2/M Checkpoints R-HSA-69481
Interleukin-1 signaling R-HSA-9020702
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
Mitotic Anaphase R-HSA-68882
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX1 R-HSA-8878171
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stimuli R-HSA-8953897
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI2 by the proteasome R-HSA-5610783
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of amino acids and derivatives R-HSA-71291
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX2 R-HSA-8878166
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Replication R-HSA-69306
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Deubiquitination R-HSA-5688426
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Transport of small molecules R-HSA-382551
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream TCR signaling R-HSA-202424
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of DVL R-HSA-4641258
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mitotic cell cycle R-HSA-453276
Interleukin-1 family signaling R-HSA-446652
Regulation of RAS by GAPs R-HSA-5658442
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RNA Polymerase II Transcription R-HSA-73857
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Axon guidance R-HSA-422475
PIP3 activates AKT signaling R-HSA-1257604
Activation of NF-kappaB in B cells R-HSA-1169091
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic Metaphase and Anaphase R-HSA-2555396
Class I MHC mediated antigen processing & presentation R-HSA-983169
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of proteins R-HSA-392499
Hh mutants are degraded by ERAD R-HSA-5362768
MAPK6/MAPK4 signaling R-HSA-5687128
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Interleukins R-HSA-449147
PCP/CE pathway R-HSA-4086400
Immune System R-HSA-168256
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
ABC transporter disorders R-HSA-5619084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Intracellular signaling by second messengers R-HSA-9006925
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hedgehog 'on' state R-HSA-5632684
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular response to hypoxia R-HSA-1234174
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle Checkpoints R-HSA-69620
NIK-->noncanonical NF-kB signaling R-HSA-5676590
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic G2-G2/M phases R-HSA-453274
Immune System R-HSA-168256
Hh mutants abrogate ligand secretion R-HSA-5387390
ABC-family proteins mediated transport R-HSA-382556
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Axon guidance R-HSA-422475
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
Metabolism R-HSA-1430728
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RAS by GAPs R-HSA-5658442
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'off' state R-HSA-5610787
Hh mutants are degraded by ERAD R-HSA-5362768
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CLEC7A (Dectin-1) signaling R-HSA-5607764
Intracellular signaling by second messengers R-HSA-9006925
Separation of Sister Chromatids R-HSA-2467813
Neddylation R-HSA-8951664
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Interleukins R-HSA-449147
Stabilization of p53 R-HSA-69541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular responses to stress R-HSA-2262752
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to hypoxia R-HSA-1234174
Degradation of GLI1 by the proteasome R-HSA-5610780
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of NF-kappaB in B cells R-HSA-1169091
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Gene expression (Transcription) R-HSA-74160
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Vif-mediated degradation of APOBEC3G R-HSA-180585
Nervous system development R-HSA-9675108
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
S Phase R-HSA-69242
Mitotic Metaphase and Anaphase R-HSA-2555396
Post-translational protein modification R-HSA-597592
HIV Infection R-HSA-162906
Apoptosis R-HSA-109581
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Deubiquitination R-HSA-5688426
Vpu mediated degradation of CD4 R-HSA-180534
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 signaling R-HSA-9020702
Developmental Biology R-HSA-1266738
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Innate Immune System R-HSA-168249
Hedgehog ligand biogenesis R-HSA-5358346
Switching of origins to a post-replicative state R-HSA-69052
G2/M Checkpoints R-HSA-69481
Programmed Cell Death R-HSA-5357801
Cellular responses to stimuli R-HSA-8953897
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PIP3 activates AKT signaling R-HSA-1257604
FCERI mediated NF-kB activation R-HSA-2871837
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of mitotic cell cycle R-HSA-453276
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
M Phase R-HSA-68886
Interleukin-1 family signaling R-HSA-446652
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disorders of transmembrane transporters R-HSA-5619115
Host Interactions of HIV factors R-HSA-162909
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by WNT R-HSA-195721
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent DNA Damage Response R-HSA-69610
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog 'on' state R-HSA-5632684
Metabolism of proteins R-HSA-392499
Cellular response to chemical stress R-HSA-9711123
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by ROBO receptors R-HSA-376176
Orc1 removal from chromatin R-HSA-68949
ABC transporter disorders R-HSA-5619084
Regulation of RUNX2 expression and activity R-HSA-8939902
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
RNA Polymerase II Transcription R-HSA-73857
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Infectious disease R-HSA-5663205
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
DNA Replication R-HSA-69306
Synthesis of DNA R-HSA-69239
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
UCH proteinases R-HSA-5689603
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK family signaling cascades R-HSA-5683057
PTEN Regulation R-HSA-6807070
Cell Cycle R-HSA-1640170
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of polyamines R-HSA-351202
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
Mitotic Anaphase R-HSA-68882
Degradation of DVL R-HSA-4641258
Transcriptional regulation by RUNX2 R-HSA-8878166
Disease R-HSA-1643685
PCP/CE pathway R-HSA-4086400
G2/M Transition R-HSA-69275
Innate Immune System R-HSA-168249
G2/M Checkpoints R-HSA-69481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Hh mutants are degraded by ERAD R-HSA-5362768
G1/S DNA Damage Checkpoints R-HSA-69615
Neddylation R-HSA-8951664
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Defective CFTR causes cystic fibrosis R-HSA-5678895
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
G2/M Transition R-HSA-69275
Cellular response to hypoxia R-HSA-1234174
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of amino acids and derivatives R-HSA-71291
Immune System R-HSA-168256
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
ABC transporter disorders R-HSA-5619084
Hedgehog 'off' state R-HSA-5610787
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
Switching of origins to a post-replicative state R-HSA-69052
Ub-specific processing proteases R-HSA-5689880
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular response to chemical stress R-HSA-9711123
Signaling by Hedgehog R-HSA-5358351
Interleukin-1 family signaling R-HSA-446652
Cell Cycle, Mitotic R-HSA-69278
Degradation of AXIN R-HSA-4641257
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of expression of SLITs and ROBOs R-HSA-9010553
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Adaptive Immune System R-HSA-1280218
Signaling by Interleukins R-HSA-449147
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by WNT R-HSA-195721
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Separation of Sister Chromatids R-HSA-2467813
Orc1 removal from chromatin R-HSA-68949
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by ROBO receptors R-HSA-376176
Regulation of RUNX2 expression and activity R-HSA-8939902
Disease R-HSA-1643685
Metabolism of polyamines R-HSA-351202
Mitotic G2-G2/M phases R-HSA-453274
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
DNA Replication R-HSA-69306
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
PCP/CE pathway R-HSA-4086400
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent DNA Damage Response R-HSA-69610
ABC-family proteins mediated transport R-HSA-382556
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
HIV Infection R-HSA-162906
Apoptosis R-HSA-109581
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK family signaling cascades R-HSA-5683057
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Vif-mediated degradation of APOBEC3G R-HSA-180585
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transport of small molecules R-HSA-382551
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI2 by the proteasome R-HSA-5610783
CLEC7A (Dectin-1) signaling R-HSA-5607764
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of Apoptosis R-HSA-169911
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle R-HSA-1640170
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Beta-catenin independent WNT signaling R-HSA-3858494
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cytokine Signaling in Immune system R-HSA-1280215
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stimuli R-HSA-8953897
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Synthesis of DNA R-HSA-69239
Axon guidance R-HSA-422475
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Programmed Cell Death R-HSA-5357801
Stabilization of p53 R-HSA-69541
UCH proteinases R-HSA-5689603
Class I MHC mediated antigen processing & presentation R-HSA-983169
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX1 R-HSA-8878171
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular responses to stress R-HSA-2262752
Synthesis of DNA R-HSA-69239
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
MAPK6/MAPK4 signaling R-HSA-5687128
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'off' state R-HSA-5610787
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Defective CFTR causes cystic fibrosis R-HSA-5678895
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
TCR signaling R-HSA-202403
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of polyamines R-HSA-351202
Signaling by ROBO receptors R-HSA-376176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Immune System R-HSA-168256
Signaling by Hedgehog R-HSA-5358351
RAF/MAP kinase cascade R-HSA-5673001
Post-translational protein modification R-HSA-597592
Metabolism of RNA R-HSA-8953854
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Disease R-HSA-1643685
Degradation of DVL R-HSA-4641258
Adaptive Immune System R-HSA-1280218
Cell Cycle, Mitotic R-HSA-69278
Signaling by WNT R-HSA-195721
Metabolism of amino acids and derivatives R-HSA-71291
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
Apoptosis R-HSA-109581
ER-Phagosome pathway R-HSA-1236974
KEAP1-NFE2L2 pathway R-HSA-9755511
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI2 by the proteasome R-HSA-5610783
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
UCH proteinases R-HSA-5689603
S Phase R-HSA-69242
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Deubiquitination R-HSA-5688426
CLEC7A (Dectin-1) signaling R-HSA-5607764
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Separation of Sister Chromatids R-HSA-2467813
Transport of small molecules R-HSA-382551
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Host Interactions of HIV factors R-HSA-162909
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PCP/CE pathway R-HSA-4086400
Downstream TCR signaling R-HSA-202424
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
Interleukin-1 signaling R-HSA-9020702
Hh mutants abrogate ligand secretion R-HSA-5387390
TCF dependent signaling in response to WNT R-HSA-201681
Infectious disease R-HSA-5663205
Degradation of AXIN R-HSA-4641257
ABC-family proteins mediated transport R-HSA-382556
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Anaphase R-HSA-68882
ABC transporter disorders R-HSA-5619084
Orc1 removal from chromatin R-HSA-68949
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
PTEN Regulation R-HSA-6807070
Hedgehog 'on' state R-HSA-5632684
Innate Immune System R-HSA-168249
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Replication R-HSA-69306
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic Metaphase and Anaphase R-HSA-2555396
Neddylation R-HSA-8951664
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to hypoxia R-HSA-1234174
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic G2-G2/M phases R-HSA-453274
Axon guidance R-HSA-422475
Regulation of Apoptosis R-HSA-169911
Programmed Cell Death R-HSA-5357801
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Stabilization of p53 R-HSA-69541
C-type lectin receptors (CLRs) R-HSA-5621481
HIV Infection R-HSA-162906
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
Metabolism of amino acids and derivatives R-HSA-71291
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Ub-specific processing proteases R-HSA-5689880
ABC-family proteins mediated transport R-HSA-382556
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
Downstream TCR signaling R-HSA-202424
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vif-mediated degradation of APOBEC3G R-HSA-180585
CLEC7A (Dectin-1) signaling R-HSA-5607764
ER-Phagosome pathway R-HSA-1236974
Cell Cycle R-HSA-1640170
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle, Mitotic R-HSA-69278
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Infectious disease R-HSA-5663205
Asymmetric localization of PCP proteins R-HSA-4608870
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of RAS by GAPs R-HSA-5658442
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Orc1 removal from chromatin R-HSA-68949
Metabolism R-HSA-1430728
p53-Dependent G1 DNA Damage Response R-HSA-69563
Programmed Cell Death R-HSA-5357801
RAF/MAP kinase cascade R-HSA-5673001
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
Regulation of PTEN stability and activity R-HSA-8948751
Host Interactions of HIV factors R-HSA-162909
C-type lectin receptors (CLRs) R-HSA-5621481
Signal Transduction R-HSA-162582
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 signaling R-HSA-9020702
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI1 by the proteasome R-HSA-5610780
UCH proteinases R-HSA-5689603
Gene expression (Transcription) R-HSA-74160
Hedgehog ligand biogenesis R-HSA-5358346
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of RNA R-HSA-8953854
Degradation of DVL R-HSA-4641258
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of polyamines R-HSA-351202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'on' state R-HSA-5632684
Intracellular signaling by second messengers R-HSA-9006925
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Transport of small molecules R-HSA-382551
Regulation of RUNX2 expression and activity R-HSA-8939902
Post-translational protein modification R-HSA-597592
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TCR signaling R-HSA-202403
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic G2-G2/M phases R-HSA-453274
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Immune System R-HSA-168256
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PCP/CE pathway R-HSA-4086400
Degradation of GLI2 by the proteasome R-HSA-5610783
Apoptosis R-HSA-109581
Neddylation R-HSA-8951664
PTEN Regulation R-HSA-6807070
Vpu mediated degradation of CD4 R-HSA-180534
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Interleukins R-HSA-449147
Beta-catenin independent WNT signaling R-HSA-3858494
Hh mutants abrogate ligand secretion R-HSA-5387390
Adaptive Immune System R-HSA-1280218
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
Disease R-HSA-1643685
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Switching of origins to a post-replicative state R-HSA-69052
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Stabilization of p53 R-HSA-69541
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of AXIN R-HSA-4641257
Separation of Sister Chromatids R-HSA-2467813
Nervous system development R-HSA-9675108
Interleukin-1 family signaling R-HSA-446652
M Phase R-HSA-68886
Signaling by ROBO receptors R-HSA-376176
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ABC transporter disorders R-HSA-5619084
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by Hedgehog R-HSA-5358351
Synthesis of DNA R-HSA-69239
Cellular response to chemical stress R-HSA-9711123
Regulation of Apoptosis R-HSA-169911
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Innate Immune System R-HSA-168249
Degradation of beta-catenin by the destruction complex R-HSA-195253
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Anaphase R-HSA-68882
Antigen processing-Cross presentation R-HSA-1236975
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle Checkpoints R-HSA-69620
Cellular response to hypoxia R-HSA-1234174
Deubiquitination R-HSA-5688426
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hedgehog 'off' state R-HSA-5610787
Neddylation R-HSA-8951664
KEAP1-NFE2L2 pathway R-HSA-9755511
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Antigen processing-Cross presentation R-HSA-1236975
G2/M Transition R-HSA-69275
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Anaphase R-HSA-68882
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK family signaling cascades R-HSA-5683057
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
Hh mutants abrogate ligand secretion R-HSA-5387390
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
HIV Infection R-HSA-162906
Hedgehog ligand biogenesis R-HSA-5358346
Hedgehog 'off' state R-HSA-5610787
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 family signaling R-HSA-446652
FCERI mediated NF-kB activation R-HSA-2871837
ER-Phagosome pathway R-HSA-1236974
Regulation of mitotic cell cycle R-HSA-453276
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
UCH proteinases R-HSA-5689603
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Separation of Sister Chromatids R-HSA-2467813
Host Interactions of HIV factors R-HSA-162909
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Disorders of transmembrane transporters R-HSA-5619115
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Hedgehog R-HSA-5358351
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of RUNX2 expression and activity R-HSA-8939902
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transport of small molecules R-HSA-382551
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
RNA Polymerase II Transcription R-HSA-73857
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
Degradation of AXIN R-HSA-4641257
p53-Independent DNA Damage Response R-HSA-69610
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by Interleukins R-HSA-449147
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular responses to stimuli R-HSA-8953897
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Gene expression (Transcription) R-HSA-74160
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism R-HSA-1430728
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Stabilization of p53 R-HSA-69541
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI2 by the proteasome R-HSA-5610783
DNA Replication R-HSA-69306
Mitotic Metaphase and Anaphase R-HSA-2555396
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vif-mediated degradation of APOBEC3G R-HSA-180585
S Phase R-HSA-69242
Apoptosis R-HSA-109581
Cellular response to chemical stress R-HSA-9711123
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle Checkpoints R-HSA-69620
Signal Transduction R-HSA-162582
Hedgehog 'on' state R-HSA-5632684
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of Apoptosis R-HSA-169911
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Programmed Cell Death R-HSA-5357801
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX1 R-HSA-8878171
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of RNA R-HSA-8953854
Cellular response to hypoxia R-HSA-1234174
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
NIK-->noncanonical NF-kB signaling R-HSA-5676590
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Synthesis of DNA R-HSA-69239
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nervous system development R-HSA-9675108
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
RAF/MAP kinase cascade R-HSA-5673001
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cytokine Signaling in Immune system R-HSA-1280215
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Cellular responses to stimuli R-HSA-8953897
MAPK family signaling cascades R-HSA-5683057
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of GLI1 by the proteasome R-HSA-5610780
Degradation of GLI2 by the proteasome R-HSA-5610783
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Immune System R-HSA-168256
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Metaphase and Anaphase R-HSA-2555396
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Transition R-HSA-69275
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Intracellular signaling by second messengers R-HSA-9006925
G1/S DNA Damage Checkpoints R-HSA-69615
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
PIP3 activates AKT signaling R-HSA-1257604
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of amino acids and derivatives R-HSA-71291
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
HIV Infection R-HSA-162906
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
Stabilization of p53 R-HSA-69541
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by Interleukins R-HSA-449147
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle R-HSA-1640170
Signaling by ROBO receptors R-HSA-376176
Signaling by WNT R-HSA-195721
MAPK6/MAPK4 signaling R-HSA-5687128
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transport of small molecules R-HSA-382551
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of proteins R-HSA-392499
Generic Transcription Pathway R-HSA-212436
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'on' state R-HSA-5632684
Deubiquitination R-HSA-5688426
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Post-translational protein modification R-HSA-597592
TCR signaling R-HSA-202403
Developmental Biology R-HSA-1266738
Cellular response to hypoxia R-HSA-1234174
Mitotic Anaphase R-HSA-68882
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of AXIN R-HSA-4641257
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent DNA Damage Response R-HSA-69610
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ub-specific processing proteases R-HSA-5689880
Regulation of mitotic cell cycle R-HSA-453276
Separation of Sister Chromatids R-HSA-2467813
Interleukin-1 signaling R-HSA-9020702
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Disease R-HSA-1643685
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK1/MAPK3 signaling R-HSA-5684996
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of DVL R-HSA-4641258
Metabolism R-HSA-1430728
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Interleukin-1 family signaling R-HSA-446652
Hedgehog 'off' state R-HSA-5610787
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX1 R-HSA-8878171
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular responses to stress R-HSA-2262752
Cell Cycle Checkpoints R-HSA-69620
DNA Replication R-HSA-69306
PCP/CE pathway R-HSA-4086400
Gene expression (Transcription) R-HSA-74160
Apoptosis R-HSA-109581
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX2 R-HSA-8878166
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Axon guidance R-HSA-422475
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hh mutants abrogate ligand secretion R-HSA-5387390
Programmed Cell Death R-HSA-5357801
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Synthesis of DNA R-HSA-69239
ABC transporter disorders R-HSA-5619084
C-type lectin receptors (CLRs) R-HSA-5621481
Orc1 removal from chromatin R-HSA-68949
Regulation of Apoptosis R-HSA-169911
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Switching of origins to a post-replicative state R-HSA-69052
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
G2/M Checkpoints R-HSA-69481
G2/M Transition R-HSA-69275
Signaling by WNT R-HSA-195721
Metabolism of proteins R-HSA-392499
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
Switching of origins to a post-replicative state R-HSA-69052
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
Regulation of Apoptosis R-HSA-169911
Defective CFTR causes cystic fibrosis R-HSA-5678895
UCH proteinases R-HSA-5689603
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Adaptive Immune System R-HSA-1280218
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Stabilization of p53 R-HSA-69541
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Regulation of RAS by GAPs R-HSA-5658442
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of mitotic cell cycle R-HSA-453276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TCF dependent signaling in response to WNT R-HSA-201681
Gene expression (Transcription) R-HSA-74160
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog 'on' state R-HSA-5632684
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Interleukins R-HSA-449147
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nervous system development R-HSA-9675108
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Apoptosis R-HSA-109581
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI2 by the proteasome R-HSA-5610783
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Post-translational protein modification R-HSA-597592
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream TCR signaling R-HSA-202424
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Checkpoints R-HSA-69481
Metabolism R-HSA-1430728
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Class I MHC mediated antigen processing & presentation R-HSA-983169
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
Programmed Cell Death R-HSA-5357801
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S DNA Damage Checkpoints R-HSA-69615
Vpu mediated degradation of CD4 R-HSA-180534
Cellular responses to stimuli R-HSA-8953897
ER-Phagosome pathway R-HSA-1236974
Cell Cycle, Mitotic R-HSA-69278
RNA Polymerase II Transcription R-HSA-73857
Disorders of transmembrane transporters R-HSA-5619115
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
Regulation of RUNX2 expression and activity R-HSA-8939902
CLEC7A (Dectin-1) signaling R-HSA-5607764
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by Hedgehog R-HSA-5358351
Hh mutants abrogate ligand secretion R-HSA-5387390
M Phase R-HSA-68886
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PCP/CE pathway R-HSA-4086400
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell Cycle R-HSA-1640170
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
Synthesis of DNA R-HSA-69239
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
ABC-family proteins mediated transport R-HSA-382556
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
Degradation of DVL R-HSA-4641258
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
C-type lectin receptors (CLRs) R-HSA-5621481
S Phase R-HSA-69242
Orc1 removal from chromatin R-HSA-68949
Signal Transduction R-HSA-162582
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX1 R-HSA-8878171
Axon guidance R-HSA-422475
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hedgehog ligand biogenesis R-HSA-5358346
Cellular response to chemical stress R-HSA-9711123
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to hypoxia R-HSA-1234174
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by ROBO receptors R-HSA-376176
Mitotic Metaphase and Anaphase R-HSA-2555396
Interleukin-1 family signaling R-HSA-446652
Metabolism of RNA R-HSA-8953854
TCR signaling R-HSA-202403
Developmental Biology R-HSA-1266738
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
HIV Infection R-HSA-162906
PTEN Regulation R-HSA-6807070
DNA Replication R-HSA-69306
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of NF-kappaB in B cells R-HSA-1169091
Hedgehog 'off' state R-HSA-5610787
Generic Transcription Pathway R-HSA-212436
Hh mutants are degraded by ERAD R-HSA-5362768

Expression Atlas ENSG00000222028
NCBI gene (formerly Entrezgene) 122706
GeneCards 31963
HGNC Symbol HGNC:31963
MIM gene 611137
UniProtKB Gene Name A5LHX3
WikiGene 122706
Gene: PSMD1
Ensembl ID : ENSG00000173692
Description: proteasome 26S subunit, non-ATPase 1
Gene Synonyms: P112,RPN2,S1
5 APIs:
211 Possible Orthologues:

Degradation of DVL R-HSA-4641258
Separation of Sister Chromatids R-HSA-2467813
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog ligand biogenesis R-HSA-5358346
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
Hedgehog 'off' state R-HSA-5610787
Metabolism R-HSA-1430728
MAPK family signaling cascades R-HSA-5683057
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
S Phase R-HSA-69242
Metabolism of proteins R-HSA-392499
PCP/CE pathway R-HSA-4086400
PTEN Regulation R-HSA-6807070
Transport of small molecules R-HSA-382551
Immune System R-HSA-168256
Programmed Cell Death R-HSA-5357801
Activation of NF-kappaB in B cells R-HSA-1169091
Stabilization of p53 R-HSA-69541
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'on' state R-HSA-5632684
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-1 signaling R-HSA-9020702
Assembly of the pre-replicative complex R-HSA-68867
Signaling by ROBO receptors R-HSA-376176
Nuclear events mediated by NFE2L2 R-HSA-9759194
ABC-family proteins mediated transport R-HSA-382556
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of polyamines R-HSA-351202
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Interleukins R-HSA-449147
M Phase R-HSA-68886
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Vpu mediated degradation of CD4 R-HSA-180534
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
Downstream TCR signaling R-HSA-202424
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of mitotic cell cycle R-HSA-453276
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S Transition R-HSA-69206
Neutrophil degranulation R-HSA-6798695
TCF dependent signaling in response to WNT R-HSA-201681
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
Orc1 removal from chromatin R-HSA-68949
MAPK1/MAPK3 signaling R-HSA-5684996
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ER-Phagosome pathway R-HSA-1236974
Cellular responses to stress R-HSA-2262752
MAPK6/MAPK4 signaling R-HSA-5687128
Disease R-HSA-1643685
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent DNA Damage Response R-HSA-69610
PIP3 activates AKT signaling R-HSA-1257604
Cellular response to hypoxia R-HSA-1234174
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Axon guidance R-HSA-422475
Degradation of AXIN R-HSA-4641257
Signaling by NOTCH R-HSA-157118
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of Apoptosis R-HSA-169911
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of RNA R-HSA-8953854
Switching of origins to a post-replicative state R-HSA-69052
Gene expression (Transcription) R-HSA-74160
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
CLEC7A (Dectin-1) signaling R-HSA-5607764
Synthesis of DNA R-HSA-69239
DNA Replication R-HSA-69306
TCR signaling R-HSA-202403
Regulation of RAS by GAPs R-HSA-5658442
Interleukin-1 family signaling R-HSA-446652
G2/M Transition R-HSA-69275
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Class I MHC mediated antigen processing & presentation R-HSA-983169
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Antigen processing-Cross presentation R-HSA-1236975
C-type lectin receptors (CLRs) R-HSA-5621481
Cytokine Signaling in Immune system R-HSA-1280215
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of DVL R-HSA-4641258
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
Neddylation R-HSA-8951664
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX3 expression and activity R-HSA-8941858
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Infectious disease R-HSA-5663205
Signaling by Hedgehog R-HSA-5358351
Mitotic G2-G2/M phases R-HSA-453274
Cellular response to chemical stress R-HSA-9711123
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
HIV Infection R-HSA-162906
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by WNT R-HSA-195721
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Host Interactions of HIV factors R-HSA-162909
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Innate Immune System R-HSA-168249
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX3 R-HSA-8878159
Ub-specific processing proteases R-HSA-5689880
Mitotic G1 phase and G1/S transition R-HSA-453279
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
NIK-->noncanonical NF-kB signaling R-HSA-5676590
FCERI mediated NF-kB activation R-HSA-2871837
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by Interleukins R-HSA-449147
Disease R-HSA-1643685
Degradation of GLI1 by the proteasome R-HSA-5610780
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
DNA Replication R-HSA-69306
UCH proteinases R-HSA-5689603
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'off' state R-HSA-5610787
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G2-G2/M phases R-HSA-453274
Antigen processing-Cross presentation R-HSA-1236975
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Neutrophil degranulation R-HSA-6798695
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular response to chemical stress R-HSA-9711123
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cell Cycle Checkpoints R-HSA-69620
FCERI mediated NF-kB activation R-HSA-2871837
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Separation of Sister Chromatids R-HSA-2467813
Generic Transcription Pathway R-HSA-212436
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by WNT R-HSA-195721
Stabilization of p53 R-HSA-69541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Host Interactions of HIV factors R-HSA-162909
Vif-mediated degradation of APOBEC3G R-HSA-180585
Downstream TCR signaling R-HSA-202424
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX3 R-HSA-8878159
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
ABC-family proteins mediated transport R-HSA-382556
ABC transporter disorders R-HSA-5619084
MAPK6/MAPK4 signaling R-HSA-5687128
Disorders of transmembrane transporters R-HSA-5619115
Signal Transduction R-HSA-162582
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stimuli R-HSA-8953897
HIV Infection R-HSA-162906
Intracellular signaling by second messengers R-HSA-9006925
Degradation of AXIN R-HSA-4641257
Signaling by NOTCH R-HSA-157118
Degradation of DVL R-HSA-4641258
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stress R-HSA-2262752
Infectious disease R-HSA-5663205
Deubiquitination R-HSA-5688426
Beta-catenin independent WNT signaling R-HSA-3858494
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Programmed Cell Death R-HSA-5357801
Metabolism of amino acids and derivatives R-HSA-71291
Innate Immune System R-HSA-168249
Signaling by Hedgehog R-HSA-5358351
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S DNA Damage Checkpoints R-HSA-69615
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Nervous system development R-HSA-9675108
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of RNA R-HSA-8953854
Regulation of RAS by GAPs R-HSA-5658442
Switching of origins to a post-replicative state R-HSA-69052
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH4 R-HSA-9013694
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of Apoptosis R-HSA-169911
Mitotic Metaphase and Anaphase R-HSA-2555396
PTEN Regulation R-HSA-6807070
Regulation of RUNX2 expression and activity R-HSA-8939902
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
C-type lectin receptors (CLRs) R-HSA-5621481
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TCR signaling R-HSA-202403
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Adaptive Immune System R-HSA-1280218
Interleukin-1 family signaling R-HSA-446652
Cell Cycle, Mitotic R-HSA-69278
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Asymmetric localization of PCP proteins R-HSA-4608870
KEAP1-NFE2L2 pathway R-HSA-9755511
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Synthesis of DNA R-HSA-69239
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent DNA Damage Response R-HSA-69610
Developmental Biology R-HSA-1266738
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog 'on' state R-HSA-5632684
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of PTEN stability and activity R-HSA-8948751
p53-Dependent G1 DNA Damage Response R-HSA-69563
G2/M Transition R-HSA-69275
Cytokine Signaling in Immune system R-HSA-1280215
DNA Replication Pre-Initiation R-HSA-69002
ER-Phagosome pathway R-HSA-1236974
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Anaphase R-HSA-68882
Metabolism of proteins R-HSA-392499
PCP/CE pathway R-HSA-4086400
Metabolism R-HSA-1430728
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TCF dependent signaling in response to WNT R-HSA-201681
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to hypoxia R-HSA-1234174
MAPK1/MAPK3 signaling R-HSA-5684996
Orc1 removal from chromatin R-HSA-68949
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog ligand biogenesis R-HSA-5358346
MAPK family signaling cascades R-HSA-5683057
G1/S Transition R-HSA-69206
Signaling by ROBO receptors R-HSA-376176
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stimuli R-HSA-8953897
Downstream TCR signaling R-HSA-202424
Infectious disease R-HSA-5663205
Regulation of expression of SLITs and ROBOs R-HSA-9010553
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic Anaphase R-HSA-68882
TCF dependent signaling in response to WNT R-HSA-201681
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX3 R-HSA-8878159
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent DNA Damage Response R-HSA-69610
Mitotic G2-G2/M phases R-HSA-453274
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle R-HSA-1640170
Synthesis of DNA R-HSA-69239
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of RAS by GAPs R-HSA-5658442
ER-Phagosome pathway R-HSA-1236974
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
MAPK family signaling cascades R-HSA-5683057
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog ligand biogenesis R-HSA-5358346
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Antigen processing-Cross presentation R-HSA-1236975
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 signaling R-HSA-9020702
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle, Mitotic R-HSA-69278
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
Metabolism of proteins R-HSA-392499
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Innate Immune System R-HSA-168249
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hh mutants abrogate ligand secretion R-HSA-5387390
MAPK6/MAPK4 signaling R-HSA-5687128
Hh mutants are degraded by ERAD R-HSA-5362768
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK1/MAPK3 signaling R-HSA-5684996
PIP3 activates AKT signaling R-HSA-1257604
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
HIV Infection R-HSA-162906
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
M Phase R-HSA-68886
Assembly of the pre-replicative complex R-HSA-68867
Cell Cycle Checkpoints R-HSA-69620
Hedgehog 'on' state R-HSA-5632684
Developmental Biology R-HSA-1266738
Degradation of AXIN R-HSA-4641257
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disease R-HSA-1643685
Regulation of PTEN stability and activity R-HSA-8948751
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RUNX2 expression and activity R-HSA-8939902
Switching of origins to a post-replicative state R-HSA-69052
C-type lectin receptors (CLRs) R-HSA-5621481
G2/M Checkpoints R-HSA-69481
Signaling by ROBO receptors R-HSA-376176
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Post-translational protein modification R-HSA-597592
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Dependent G1 DNA Damage Response R-HSA-69563
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH R-HSA-157118
Orc1 removal from chromatin R-HSA-68949
Degradation of beta-catenin by the destruction complex R-HSA-195253
KEAP1-NFE2L2 pathway R-HSA-9755511
ABC transporter disorders R-HSA-5619084
Regulation of mitotic cell cycle R-HSA-453276
Cellular responses to stress R-HSA-2262752
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PTEN Regulation R-HSA-6807070
Neutrophil degranulation R-HSA-6798695
Metabolism of polyamines R-HSA-351202
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ub-specific processing proteases R-HSA-5689880
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
RNA Polymerase II Transcription R-HSA-73857
PCP/CE pathway R-HSA-4086400
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'off' state R-HSA-5610787
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism R-HSA-1430728
Signaling by Hedgehog R-HSA-5358351
DNA Replication Pre-Initiation R-HSA-69002
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Beta-catenin independent WNT signaling R-HSA-3858494
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX2 R-HSA-8878166
Separation of Sister Chromatids R-HSA-2467813
Disorders of transmembrane transporters R-HSA-5619115
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
DNA Replication R-HSA-69306
Deubiquitination R-HSA-5688426
Signaling by NOTCH4 R-HSA-9013694
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
S Phase R-HSA-69242
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S DNA Damage Checkpoints R-HSA-69615
Programmed Cell Death R-HSA-5357801
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G1/S Transition R-HSA-69206
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Nervous system development R-HSA-9675108
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by WNT R-HSA-195721
Neddylation R-HSA-8951664
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transport of small molecules R-HSA-382551
Host Interactions of HIV factors R-HSA-162909
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of Apoptosis R-HSA-169911
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
M Phase R-HSA-68886
Regulation of Apoptosis R-HSA-169911
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Hedgehog R-HSA-5358351
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Host Interactions of HIV factors R-HSA-162909
Antigen processing-Cross presentation R-HSA-1236975
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Metaphase and Anaphase R-HSA-2555396
HIV Infection R-HSA-162906
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PCP/CE pathway R-HSA-4086400
ABC transporter disorders R-HSA-5619084
Hh mutants are degraded by ERAD R-HSA-5362768
ABC-family proteins mediated transport R-HSA-382556
Regulation of PTEN stability and activity R-HSA-8948751
Adaptive Immune System R-HSA-1280218
Metabolism of RNA R-HSA-8953854
Neutrophil degranulation R-HSA-6798695
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Deubiquitination R-HSA-5688426
G2/M Transition R-HSA-69275
S Phase R-HSA-69242
Degradation of AXIN R-HSA-4641257
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK6/MAPK4 signaling R-HSA-5687128
Programmed Cell Death R-HSA-5357801
Signaling by ROBO receptors R-HSA-376176
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by NOTCH4 R-HSA-9013694
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle R-HSA-1640170
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
MAPK family signaling cascades R-HSA-5683057
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH R-HSA-157118
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TCF dependent signaling in response to WNT R-HSA-201681
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular response to chemical stress R-HSA-9711123
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX2 R-HSA-8878166
Interleukin-1 signaling R-HSA-9020702
Cyclin E associated events during G1/S transition R-HSA-69202
Transport of small molecules R-HSA-382551
Nervous system development R-HSA-9675108
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
Metabolism of proteins R-HSA-392499
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Innate Immune System R-HSA-168249
Degradation of DVL R-HSA-4641258
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
Stabilization of p53 R-HSA-69541
Regulation of mitotic cell cycle R-HSA-453276
Axon guidance R-HSA-422475
p53-Independent DNA Damage Response R-HSA-69610
Cellular responses to stress R-HSA-2262752
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Post-translational protein modification R-HSA-597592
Synthesis of DNA R-HSA-69239
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Anaphase R-HSA-68882
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication R-HSA-69306
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Developmental Biology R-HSA-1266738
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hedgehog 'on' state R-HSA-5632684
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism R-HSA-1430728
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 family signaling R-HSA-446652
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RUNX3 expression and activity R-HSA-8941858
ER-Phagosome pathway R-HSA-1236974
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
Ub-specific processing proteases R-HSA-5689880
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PTEN Regulation R-HSA-6807070
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle, Mitotic R-HSA-69278
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Nuclear events mediated by NFE2L2 R-HSA-9759194
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Hedgehog 'off' state R-HSA-5610787
Metabolism of polyamines R-HSA-351202
Assembly of the pre-replicative complex R-HSA-68867
Orc1 removal from chromatin R-HSA-68949
Cellular responses to stimuli R-HSA-8953897
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of RAS by GAPs R-HSA-5658442
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Generic Transcription Pathway R-HSA-212436
p53-Dependent G1 DNA Damage Response R-HSA-69563
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Apoptosis R-HSA-109581
DNA Replication Pre-Initiation R-HSA-69002
Signaling by WNT R-HSA-195721
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PIP3 activates AKT signaling R-HSA-1257604
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
RAF/MAP kinase cascade R-HSA-5673001
KEAP1-NFE2L2 pathway R-HSA-9755511
CLEC7A (Dectin-1) signaling R-HSA-5607764
Switching of origins to a post-replicative state R-HSA-69052
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by Interleukins R-HSA-449147
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by the B Cell Receptor (BCR) R-HSA-983705
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
G1/S Transition R-HSA-69206
Degradation of beta-catenin by the destruction complex R-HSA-195253
TCR signaling R-HSA-202403
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle Checkpoints R-HSA-69620
UCH proteinases R-HSA-5689603
Metabolism of amino acids and derivatives R-HSA-71291
Disorders of transmembrane transporters R-HSA-5619115
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional regulation by RUNX3 R-HSA-8878159
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Vif-mediated degradation of APOBEC3G R-HSA-180585
Class I MHC mediated antigen processing & presentation R-HSA-983169
Asymmetric localization of PCP proteins R-HSA-4608870
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cyclin E associated events during G1/S transition R-HSA-69202
Activation of NF-kappaB in B cells R-HSA-1169091
Deubiquitination R-HSA-5688426
Degradation of GLI1 by the proteasome R-HSA-5610780
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
Signaling by NOTCH4 R-HSA-9013694
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular response to hypoxia R-HSA-1234174
Nuclear events mediated by NFE2L2 R-HSA-9759194
MAPK family signaling cascades R-HSA-5683057
Metabolism R-HSA-1430728
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
DNA Replication R-HSA-69306
Interleukin-1 signaling R-HSA-9020702
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Programmed Cell Death R-HSA-5357801
Downstream TCR signaling R-HSA-202424
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hh mutants are degraded by ERAD R-HSA-5362768
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Ub-specific processing proteases R-HSA-5689880
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transport of small molecules R-HSA-382551
Transcriptional regulation by RUNX2 R-HSA-8878166
M Phase R-HSA-68886
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of GLI2 by the proteasome R-HSA-5610783
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Stabilization of p53 R-HSA-69541
Signaling by Hedgehog R-HSA-5358351
Regulation of mitotic cell cycle R-HSA-453276
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Independent DNA Damage Response R-HSA-69610
Adaptive Immune System R-HSA-1280218
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by WNT R-HSA-195721
Switching of origins to a post-replicative state R-HSA-69052
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'off' state R-HSA-5610787
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
G1/S DNA Damage Checkpoints R-HSA-69615
RAF/MAP kinase cascade R-HSA-5673001
Post-translational protein modification R-HSA-597592
G2/M Transition R-HSA-69275
Immune System R-HSA-168256
Cellular response to chemical stress R-HSA-9711123
Axon guidance R-HSA-422475
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing-Cross presentation R-HSA-1236975
Mitotic Metaphase and Anaphase R-HSA-2555396
ABC transporter disorders R-HSA-5619084
Apoptosis R-HSA-109581
Intracellular signaling by second messengers R-HSA-9006925
ABC-family proteins mediated transport R-HSA-382556
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
S Phase R-HSA-69242
FCERI mediated NF-kB activation R-HSA-2871837
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Host Interactions of HIV factors R-HSA-162909
Degradation of AXIN R-HSA-4641257
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
ER-Phagosome pathway R-HSA-1236974
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Anaphase R-HSA-68882
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by ROBO receptors R-HSA-376176
Generic Transcription Pathway R-HSA-212436
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic G1 phase and G1/S transition R-HSA-453279
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
HIV Infection R-HSA-162906
TCR signaling R-HSA-202403
Infectious disease R-HSA-5663205
G1/S Transition R-HSA-69206
Cell Cycle Checkpoints R-HSA-69620
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of RAS by GAPs R-HSA-5658442
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by NOTCH R-HSA-157118
Synthesis of DNA R-HSA-69239
TCF dependent signaling in response to WNT R-HSA-201681
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Nervous system development R-HSA-9675108
Regulation of RUNX2 expression and activity R-HSA-8939902
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
Separation of Sister Chromatids R-HSA-2467813
Negative regulation of NOTCH4 signaling R-HSA-9604323
G2/M Checkpoints R-HSA-69481
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Neutrophil degranulation R-HSA-6798695
DNA Replication Pre-Initiation R-HSA-69002
Neddylation R-HSA-8951664
Degradation of DVL R-HSA-4641258
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of polyamines R-HSA-351202
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of beta-catenin by the destruction complex R-HSA-195253
UCH proteinases R-HSA-5689603
Signaling by Interleukins R-HSA-449147
Regulation of RUNX3 expression and activity R-HSA-8941858
Vpu mediated degradation of CD4 R-HSA-180534
Orc1 removal from chromatin R-HSA-68949
PTEN Regulation R-HSA-6807070
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stimuli R-HSA-8953897
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of expression of SLITs and ROBOs R-HSA-9010553
RNA Polymerase II Transcription R-HSA-73857
Signaling by Hedgehog R-HSA-5358351
G2/M Checkpoints R-HSA-69481
Metabolism of RNA R-HSA-8953854
Cellular responses to stress R-HSA-2262752
Signaling by Interleukins R-HSA-449147
Signaling by WNT R-HSA-195721
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Innate Immune System R-HSA-168249
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by NOTCH R-HSA-157118
Hh mutants are degraded by ERAD R-HSA-5362768
Transport of small molecules R-HSA-382551
Neddylation R-HSA-8951664
Disorders of transmembrane transporters R-HSA-5619115
Nuclear events mediated by NFE2L2 R-HSA-9759194
Infectious disease R-HSA-5663205
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular response to hypoxia R-HSA-1234174
Axon guidance R-HSA-422475
p53-Dependent G1 DNA Damage Response R-HSA-69563
Vpu mediated degradation of CD4 R-HSA-180534
S Phase R-HSA-69242
Separation of Sister Chromatids R-HSA-2467813
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication Pre-Initiation R-HSA-69002
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by ROBO receptors R-HSA-376176
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Metabolism R-HSA-1430728
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of AXIN R-HSA-4641257
Assembly of the pre-replicative complex R-HSA-68867
Hedgehog 'on' state R-HSA-5632684
Disease R-HSA-1643685
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nervous system development R-HSA-9675108
Degradation of DVL R-HSA-4641258
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle R-HSA-1640170
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Orc1 removal from chromatin R-HSA-68949
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic Anaphase R-HSA-68882
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle, Mitotic R-HSA-69278
Programmed Cell Death R-HSA-5357801
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Neutrophil degranulation R-HSA-6798695
Intracellular signaling by second messengers R-HSA-9006925
C-type lectin receptors (CLRs) R-HSA-5621481
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
PIP3 activates AKT signaling R-HSA-1257604
HIV Infection R-HSA-162906
Negative regulation of NOTCH4 signaling R-HSA-9604323
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Deubiquitination R-HSA-5688426
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
TCF dependent signaling in response to WNT R-HSA-201681
Signal Transduction R-HSA-162582
p53-Independent DNA Damage Response R-HSA-69610
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RUNX3 expression and activity R-HSA-8941858
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ABC-family proteins mediated transport R-HSA-382556
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCR signaling R-HSA-202403
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transcriptional regulation by RUNX3 R-HSA-8878159
Class I MHC mediated antigen processing & presentation R-HSA-983169
Beta-catenin independent WNT signaling R-HSA-3858494
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream TCR signaling R-HSA-202424
Hedgehog 'off' state R-HSA-5610787
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of Apoptosis R-HSA-169911
Regulation of mitotic cell cycle R-HSA-453276
Cellular responses to stimuli R-HSA-8953897
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Generic Transcription Pathway R-HSA-212436
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
RAF/MAP kinase cascade R-HSA-5673001
Apoptosis R-HSA-109581
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
M Phase R-HSA-68886
Synthesis of DNA R-HSA-69239
Interleukin-1 signaling R-HSA-9020702
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cyclin E associated events during G1/S transition R-HSA-69202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of amino acids and derivatives R-HSA-71291
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Cell Cycle Checkpoints R-HSA-69620
Asymmetric localization of PCP proteins R-HSA-4608870
Developmental Biology R-HSA-1266738
ER-Phagosome pathway R-HSA-1236974
Metabolism of proteins R-HSA-392499
Mitotic G2-G2/M phases R-HSA-453274
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog ligand biogenesis R-HSA-5358346
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Cellular response to chemical stress R-HSA-9711123
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of GLI1 by the proteasome R-HSA-5610780
Switching of origins to a post-replicative state R-HSA-69052
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Gene expression (Transcription) R-HSA-74160
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of Apoptosis R-HSA-169911
Degradation of AXIN R-HSA-4641257
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hedgehog 'on' state R-HSA-5632684
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle, Mitotic R-HSA-69278
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
Signaling by Hedgehog R-HSA-5358351
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ER-Phagosome pathway R-HSA-1236974
Cell Cycle Checkpoints R-HSA-69620
Intracellular signaling by second messengers R-HSA-9006925
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle R-HSA-1640170
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Signaling by NOTCH4 R-HSA-9013694
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of RUNX3 expression and activity R-HSA-8941858
TCF dependent signaling in response to WNT R-HSA-201681
ABC transporter disorders R-HSA-5619084
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
Synthesis of DNA R-HSA-69239
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX3 R-HSA-8878159
Neddylation R-HSA-8951664
Post-translational protein modification R-HSA-597592
Deubiquitination R-HSA-5688426
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of GLI2 by the proteasome R-HSA-5610783
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G1/S Transition R-HSA-69206
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Interleukins R-HSA-449147
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Defective CFTR causes cystic fibrosis R-HSA-5678895
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of PTEN stability and activity R-HSA-8948751
Infectious disease R-HSA-5663205
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
Ub-specific processing proteases R-HSA-5689880
Cyclin E associated events during G1/S transition R-HSA-69202
Hh mutants abrogate ligand secretion R-HSA-5387390
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog 'off' state R-HSA-5610787
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK6/MAPK4 signaling R-HSA-5687128
PTEN Regulation R-HSA-6807070
RAF/MAP kinase cascade R-HSA-5673001
Adaptive Immune System R-HSA-1280218
G2/M Checkpoints R-HSA-69481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
C-type lectin receptors (CLRs) R-HSA-5621481
Neutrophil degranulation R-HSA-6798695
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
MAPK1/MAPK3 signaling R-HSA-5684996
Programmed Cell Death R-HSA-5357801
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Beta-catenin independent WNT signaling R-HSA-3858494
p53-Independent DNA Damage Response R-HSA-69610
Disorders of transmembrane transporters R-HSA-5619115
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Activation of NF-kappaB in B cells R-HSA-1169091
Downstream TCR signaling R-HSA-202424
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Mitotic Metaphase and Anaphase R-HSA-2555396
Nervous system development R-HSA-9675108
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 signaling R-HSA-9020702
Generic Transcription Pathway R-HSA-212436
DNA Replication R-HSA-69306
Immune System R-HSA-168256
Cellular responses to stress R-HSA-2262752
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cytokine Signaling in Immune system R-HSA-1280215
Apoptosis R-HSA-109581
Metabolism of polyamines R-HSA-351202
G2/M Transition R-HSA-69275
Nuclear events mediated by NFE2L2 R-HSA-9759194
Orc1 removal from chromatin R-HSA-68949
Regulation of mitotic cell cycle R-HSA-453276
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Switching of origins to a post-replicative state R-HSA-69052
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Vpu mediated degradation of CD4 R-HSA-180534
S Phase R-HSA-69242
Degradation of DVL R-HSA-4641258
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by WNT R-HSA-195721
Regulation of RAS by GAPs R-HSA-5658442
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PCP/CE pathway R-HSA-4086400
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hh mutants are degraded by ERAD R-HSA-5362768
Transport of small molecules R-HSA-382551
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX1 R-HSA-8878171
Stabilization of p53 R-HSA-69541
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular responses to stimuli R-HSA-8953897
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
Host Interactions of HIV factors R-HSA-162909
Metabolism R-HSA-1430728
Interleukin-1 family signaling R-HSA-446652
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of RNA R-HSA-8953854
Ub-specific processing proteases R-HSA-5689880
Signaling by ROBO receptors R-HSA-376176
Metabolism of proteins R-HSA-392499
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
Hh mutants are degraded by ERAD R-HSA-5362768
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'on' state R-HSA-5632684
Metabolism R-HSA-1430728
Degradation of GLI1 by the proteasome R-HSA-5610780
PIP3 activates AKT signaling R-HSA-1257604
DNA Replication R-HSA-69306
Disease R-HSA-1643685
Metabolism of polyamines R-HSA-351202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Synthesis of DNA R-HSA-69239
Programmed Cell Death R-HSA-5357801
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stress R-HSA-2262752
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Innate Immune System R-HSA-168249
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Metaphase and Anaphase R-HSA-2555396
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of Apoptosis R-HSA-169911
Cyclin E associated events during G1/S transition R-HSA-69202
Orc1 removal from chromatin R-HSA-68949
Degradation of DVL R-HSA-4641258
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
Neddylation R-HSA-8951664
FCERI mediated NF-kB activation R-HSA-2871837
G2/M Checkpoints R-HSA-69481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Intracellular signaling by second messengers R-HSA-9006925
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK1/MAPK3 signaling R-HSA-5684996
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RAS by GAPs R-HSA-5658442
Mitotic G2-G2/M phases R-HSA-453274
Apoptosis R-HSA-109581
PCP/CE pathway R-HSA-4086400
Signaling by Hedgehog R-HSA-5358351
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stimuli R-HSA-8953897
PTEN Regulation R-HSA-6807070
Cellular response to chemical stress R-HSA-9711123
Transport of small molecules R-HSA-382551
Cell Cycle R-HSA-1640170
Class I MHC mediated antigen processing & presentation R-HSA-983169
Signaling by WNT R-HSA-195721
p53-Independent DNA Damage Response R-HSA-69610
ER-Phagosome pathway R-HSA-1236974
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream TCR signaling R-HSA-202424
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of AXIN R-HSA-4641257
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK6/MAPK4 signaling R-HSA-5687128
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Interleukin-1 signaling R-HSA-9020702
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX3 R-HSA-8878159
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Deubiquitination R-HSA-5688426
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by NOTCH4 R-HSA-9013694
Disorders of transmembrane transporters R-HSA-5619115
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Host Interactions of HIV factors R-HSA-162909
Mitotic G1 phase and G1/S transition R-HSA-453279
HIV Infection R-HSA-162906
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Adaptive Immune System R-HSA-1280218
Gene expression (Transcription) R-HSA-74160
Degradation of GLI2 by the proteasome R-HSA-5610783
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Vpu mediated degradation of CD4 R-HSA-180534
G1/S Transition R-HSA-69206
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH R-HSA-157118
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ABC-family proteins mediated transport R-HSA-382556
Nervous system development R-HSA-9675108
TCR signaling R-HSA-202403
Infectious disease R-HSA-5663205
Cell Cycle Checkpoints R-HSA-69620
Neutrophil degranulation R-HSA-6798695
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
G2/M Transition R-HSA-69275
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
DNA Replication Pre-Initiation R-HSA-69002
Vif-mediated degradation of APOBEC3G R-HSA-180585
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signal Transduction R-HSA-162582
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
UCH proteinases R-HSA-5689603
Degradation of beta-catenin by the destruction complex R-HSA-195253
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
Switching of origins to a post-replicative state R-HSA-69052
Mitotic Anaphase R-HSA-68882
Beta-catenin independent WNT signaling R-HSA-3858494
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
G2/M Checkpoints R-HSA-69481
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RNA Polymerase II Transcription R-HSA-73857
ABC transporter disorders R-HSA-5619084
Axon guidance R-HSA-422475
HIV Infection R-HSA-162906
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of Apoptosis R-HSA-169911
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
PCP/CE pathway R-HSA-4086400
Degradation of DVL R-HSA-4641258
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog 'on' state R-HSA-5632684
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
UCH proteinases R-HSA-5689603
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cytokine Signaling in Immune system R-HSA-1280215
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH R-HSA-157118
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
Infectious disease R-HSA-5663205
Nuclear events mediated by NFE2L2 R-HSA-9759194
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Deubiquitination R-HSA-5688426
ER-Phagosome pathway R-HSA-1236974
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
Cell Cycle, Mitotic R-HSA-69278
Mitotic Anaphase R-HSA-68882
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CLEC7A (Dectin-1) signaling R-HSA-5607764
Developmental Biology R-HSA-1266738
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to chemical stress R-HSA-9711123
Orc1 removal from chromatin R-HSA-68949
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle Checkpoints R-HSA-69620
FCERI mediated NF-kB activation R-HSA-2871837
p53-Dependent G1 DNA Damage Response R-HSA-69563
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic Metaphase and Anaphase R-HSA-2555396
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S Transition R-HSA-69206
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
TCF dependent signaling in response to WNT R-HSA-201681
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by WNT R-HSA-195721
Hh mutants are degraded by ERAD R-HSA-5362768
Programmed Cell Death R-HSA-5357801
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Downstream TCR signaling R-HSA-202424
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Gene expression (Transcription) R-HSA-74160
Neddylation R-HSA-8951664
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Adaptive Immune System R-HSA-1280218
Mitotic G2-G2/M phases R-HSA-453274
Synthesis of DNA R-HSA-69239
Beta-catenin independent WNT signaling R-HSA-3858494
Innate Immune System R-HSA-168249
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK family signaling cascades R-HSA-5683057
Cell Cycle R-HSA-1640170
DNA Replication Pre-Initiation R-HSA-69002
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RAS by GAPs R-HSA-5658442
Activation of NF-kappaB in B cells R-HSA-1169091
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
Metabolism of proteins R-HSA-392499
Metabolism of polyamines R-HSA-351202
Ub-specific processing proteases R-HSA-5689880
Cellular responses to stimuli R-HSA-8953897
Hedgehog ligand biogenesis R-HSA-5358346
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to hypoxia R-HSA-1234174
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Defective CFTR causes cystic fibrosis R-HSA-5678895
DNA Replication R-HSA-69306
Apoptosis R-HSA-109581
Immune System R-HSA-168256
Mitotic G1 phase and G1/S transition R-HSA-453279
S Phase R-HSA-69242
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC-family proteins mediated transport R-HSA-382556
Degradation of GLI2 by the proteasome R-HSA-5610783
Assembly of the pre-replicative complex R-HSA-68867
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of RNA R-HSA-8953854
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S DNA Damage Checkpoints R-HSA-69615
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
p53-Independent DNA Damage Response R-HSA-69610
Metabolism R-HSA-1430728
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
KEAP1-NFE2L2 pathway R-HSA-9755511
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX1 R-HSA-8878171
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX2 R-HSA-8878166
Neutrophil degranulation R-HSA-6798695
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of AXIN R-HSA-4641257
Stabilization of p53 R-HSA-69541
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'on' state R-HSA-5632684
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Asymmetric localization of PCP proteins R-HSA-4608870
Signal Transduction R-HSA-162582
UCH proteinases R-HSA-5689603
G2/M Transition R-HSA-69275
Signaling by Hedgehog R-HSA-5358351
Adaptive Immune System R-HSA-1280218
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of RNA R-HSA-8953854
Nuclear events mediated by NFE2L2 R-HSA-9759194
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
Mitotic Anaphase R-HSA-68882
Neddylation R-HSA-8951664
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
ABC transporter disorders R-HSA-5619084
Beta-catenin independent WNT signaling R-HSA-3858494
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ER-Phagosome pathway R-HSA-1236974
Neutrophil degranulation R-HSA-6798695
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
Degradation of GLI2 by the proteasome R-HSA-5610783
Mitotic G2-G2/M phases R-HSA-453274
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Degradation of DVL R-HSA-4641258
Signaling by WNT R-HSA-195721
Nervous system development R-HSA-9675108
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RAF/MAP kinase cascade R-HSA-5673001
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle Checkpoints R-HSA-69620
DNA Replication R-HSA-69306
p53-Independent DNA Damage Response R-HSA-69610
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of AXIN R-HSA-4641257
Regulation of mitotic cell cycle R-HSA-453276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cytokine Signaling in Immune system R-HSA-1280215
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by Interleukins R-HSA-449147
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of proteins R-HSA-392499
MAPK6/MAPK4 signaling R-HSA-5687128
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Deubiquitination R-HSA-5688426
Metabolism R-HSA-1430728
FCERI mediated NF-kB activation R-HSA-2871837
PIP3 activates AKT signaling R-HSA-1257604
RNA Polymerase II Transcription R-HSA-73857
Stabilization of p53 R-HSA-69541
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
G1/S Transition R-HSA-69206
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hedgehog 'off' state R-HSA-5610787
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle R-HSA-1640170
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Disorders of transmembrane transporters R-HSA-5619115
Post-translational protein modification R-HSA-597592
Metabolism of polyamines R-HSA-351202
Immune System R-HSA-168256
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Synthesis of DNA R-HSA-69239
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
M Phase R-HSA-68886
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Interleukin-1 signaling R-HSA-9020702
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
Activation of NF-kappaB in B cells R-HSA-1169091
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
MAPK family signaling cascades R-HSA-5683057
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing-Cross presentation R-HSA-1236975
Vpu mediated degradation of CD4 R-HSA-180534
Vif-mediated degradation of APOBEC3G R-HSA-180585
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle, Mitotic R-HSA-69278
Gene expression (Transcription) R-HSA-74160
Degradation of beta-catenin by the destruction complex R-HSA-195253
Orc1 removal from chromatin R-HSA-68949
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular responses to stimuli R-HSA-8953897
CLEC7A (Dectin-1) signaling R-HSA-5607764
ABC-family proteins mediated transport R-HSA-382556
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Class I MHC mediated antigen processing & presentation R-HSA-983169
Downstream TCR signaling R-HSA-202424
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
Signaling by ROBO receptors R-HSA-376176
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Infectious disease R-HSA-5663205
Intracellular signaling by second messengers R-HSA-9006925
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ub-specific processing proteases R-HSA-5689880
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of PTEN stability and activity R-HSA-8948751
PCP/CE pathway R-HSA-4086400
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Apoptosis R-HSA-109581
G2/M Checkpoints R-HSA-69481
TCF dependent signaling in response to WNT R-HSA-201681
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of Apoptosis R-HSA-169911
Synthesis of DNA R-HSA-69239
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic G1 phase and G1/S transition R-HSA-453279
Programmed Cell Death R-HSA-5357801
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Ub-specific processing proteases R-HSA-5689880
Axon guidance R-HSA-422475
Mitotic Anaphase R-HSA-68882
Switching of origins to a post-replicative state R-HSA-69052
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK1/MAPK3 signaling R-HSA-5684996
Separation of Sister Chromatids R-HSA-2467813
Generic Transcription Pathway R-HSA-212436
Stabilization of p53 R-HSA-69541
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Hedgehog R-HSA-5358351
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of PTEN stability and activity R-HSA-8948751
Assembly of the pre-replicative complex R-HSA-68867
Apoptosis R-HSA-109581
Cell Cycle R-HSA-1640170
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle, Mitotic R-HSA-69278
S Phase R-HSA-69242
Cellular response to hypoxia R-HSA-1234174
Signaling by Interleukins R-HSA-449147
Neutrophil degranulation R-HSA-6798695
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'off' state R-HSA-5610787
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
ABC transporter disorders R-HSA-5619084
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
G2/M Transition R-HSA-69275
ER-Phagosome pathway R-HSA-1236974
G1/S Transition R-HSA-69206
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of beta-catenin by the destruction complex R-HSA-195253
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular response to chemical stress R-HSA-9711123
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neddylation R-HSA-8951664
DNA Replication Pre-Initiation R-HSA-69002
Interleukin-1 signaling R-HSA-9020702
PCP/CE pathway R-HSA-4086400
ABC-family proteins mediated transport R-HSA-382556
PIP3 activates AKT signaling R-HSA-1257604
PTEN Regulation R-HSA-6807070
Degradation of AXIN R-HSA-4641257
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream TCR signaling R-HSA-202424
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'on' state R-HSA-5632684
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G2/M Checkpoints R-HSA-69481
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX2 R-HSA-8878166
Disorders of transmembrane transporters R-HSA-5619115
UCH proteinases R-HSA-5689603
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Immune System R-HSA-168256
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of RNA R-HSA-8953854
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
Signal Transduction R-HSA-162582
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by NOTCH R-HSA-157118
MAPK6/MAPK4 signaling R-HSA-5687128
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism R-HSA-1430728
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transport of small molecules R-HSA-382551
Metabolism of amino acids and derivatives R-HSA-71291
Post-translational protein modification R-HSA-597592
Orc1 removal from chromatin R-HSA-68949
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by ROBO receptors R-HSA-376176
TCR signaling R-HSA-202403
Degradation of DVL R-HSA-4641258
Signaling by NOTCH4 R-HSA-9013694
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vif-mediated degradation of APOBEC3G R-HSA-180585
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Dependent G1 DNA Damage Response R-HSA-69563
Mitotic G2-G2/M phases R-HSA-453274
Gene expression (Transcription) R-HSA-74160
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
TCF dependent signaling in response to WNT R-HSA-201681
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent DNA Damage Response R-HSA-69610
RAF/MAP kinase cascade R-HSA-5673001
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cell Cycle Checkpoints R-HSA-69620
Metabolism of proteins R-HSA-392499
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hh mutants are degraded by ERAD R-HSA-5362768
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
DNA Replication R-HSA-69306
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Deubiquitination R-HSA-5688426
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
Regulation of Apoptosis R-HSA-169911
Hedgehog ligand biogenesis R-HSA-5358346
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RAS by GAPs R-HSA-5658442
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of polyamines R-HSA-351202
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stress R-HSA-2262752

Expression Atlas ENSG00000173692
NCBI gene (formerly Entrezgene) 5707
GeneCards 9554
HGNC Symbol HGNC:9554
MIM gene 617842
UniProtKB Gene Name Q99460
WikiGene 5707
Gene: APH1B
Ensembl ID : ENSG00000138613
Description: aph-1 homolog B, gamma-secretase subunit
Gene Synonyms: APH-1B,DKFZP564D0372,PSFL
5 APIs:
193 Possible Orthologues:

Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH4 R-HSA-9013694
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Axon guidance R-HSA-422475
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH2 R-HSA-1980145
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NRIF signals cell death from the nucleus R-HSA-205043
Regulated proteolysis of p75NTR R-HSA-193692
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
p75 NTR receptor-mediated signalling R-HSA-193704
Nervous system development R-HSA-9675108
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Nuclear signaling by ERBB4 R-HSA-1251985
Disease R-HSA-1643685
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH1 in Cancer R-HSA-2644603
Nuclear signaling by ERBB4 R-HSA-1251985
Signal Transduction R-HSA-162582
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH4 R-HSA-9013694
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p75 NTR receptor-mediated signalling R-HSA-193704
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Metabolism of proteins R-HSA-392499
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH2 R-HSA-1980145
Regulated proteolysis of p75NTR R-HSA-193692
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 R-HSA-1980143
NRIF signals cell death from the nucleus R-HSA-205043
Noncanonical activation of NOTCH3 R-HSA-9017802
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
Signaling by NOTCH2 R-HSA-1980145
Metabolism of proteins R-HSA-392499
Signaling by ERBB4 R-HSA-1236394
EPH-Ephrin signaling R-HSA-2682334
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Regulated proteolysis of p75NTR R-HSA-193692
Nervous system development R-HSA-9675108
Nuclear signaling by ERBB4 R-HSA-1251985
p75 NTR receptor-mediated signalling R-HSA-193704
NRIF signals cell death from the nucleus R-HSA-205043
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Disease R-HSA-1643685
Signaling by NOTCH1 R-HSA-1980143
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH4 R-HSA-9013694
Death Receptor Signaling R-HSA-73887
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH4 R-HSA-9013694
Regulated proteolysis of p75NTR R-HSA-193692
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Signaling by NOTCH2 R-HSA-1980145
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH3 R-HSA-9012852
Death Receptor Signaling R-HSA-73887
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NRIF signals cell death from the nucleus R-HSA-205043
Developmental Biology R-HSA-1266738
Amyloid fiber formation R-HSA-977225
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by ERBB4 R-HSA-1236394
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Nuclear signaling by ERBB4 R-HSA-1251985
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 R-HSA-1980143
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 R-HSA-1980143
p75 NTR receptor-mediated signalling R-HSA-193704
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Amyloid fiber formation R-HSA-977225
Nervous system development R-HSA-9675108
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nuclear signaling by ERBB4 R-HSA-1251985
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by ERBB4 R-HSA-1236394
EPH-Ephrin signaling R-HSA-2682334
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 in Cancer R-HSA-2644603
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signal Transduction R-HSA-162582
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH3 R-HSA-9012852
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH3 R-HSA-9012852
Nuclear signaling by ERBB4 R-HSA-1251985
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by ERBB4 R-HSA-1236394
Amyloid fiber formation R-HSA-977225
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 R-HSA-1980143
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Nervous system development R-HSA-9675108
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulated proteolysis of p75NTR R-HSA-193692
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH2 R-HSA-1980145
Axon guidance R-HSA-422475
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by ERBB4 R-HSA-1236394
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 in Cancer R-HSA-2644603
Death Receptor Signaling R-HSA-73887
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Metabolism of proteins R-HSA-392499
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH2 R-HSA-1980145
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH R-HSA-157118
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Amyloid fiber formation R-HSA-977225
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH2 R-HSA-1980145
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
Nuclear signaling by ERBB4 R-HSA-1251985
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 in Cancer R-HSA-2644603
Noncanonical activation of NOTCH3 R-HSA-9017802
Metabolism of proteins R-HSA-392499
Axon guidance R-HSA-422475
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Amyloid fiber formation R-HSA-977225
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
Regulated proteolysis of p75NTR R-HSA-193692
Amyloid fiber formation R-HSA-977225
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Regulated proteolysis of p75NTR R-HSA-193692
Noncanonical activation of NOTCH3 R-HSA-9017802
Signal Transduction R-HSA-162582
Nuclear signaling by ERBB4 R-HSA-1251985
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Axon guidance R-HSA-422475
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH3 R-HSA-9012852
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
Metabolism of proteins R-HSA-392499
NRIF signals cell death from the nucleus R-HSA-205043
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Signaling by NOTCH4 R-HSA-9013694
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH2 R-HSA-1980145

Expression Atlas ENSG00000138613
NCBI gene (formerly Entrezgene) 83464
GeneCards 24080
HGNC Symbol HGNC:24080
MIM gene 607630
UniProtKB Gene Name Q8WW43
WikiGene 83464
Gene: LTA4H
Ensembl ID : ENSG00000111144
Description: leukotriene A4 hydrolase
Gene Synonyms:
1 APIs:
207 Possible Orthologues:

Biosynthesis of DHA-derived SPMs R-HSA-9018677
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Metabolism R-HSA-1430728
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Metabolism of lipids R-HSA-556833
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Biosynthesis of D-series resolvins R-HSA-9018676
Biosynthesis of protectins R-HSA-9018681
Fatty acid metabolism R-HSA-8978868
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Metabolism of lipids R-HSA-556833
Biosynthesis of protectins R-HSA-9018681
Neutrophil degranulation R-HSA-6798695
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Fatty acid metabolism R-HSA-8978868
Biosynthesis of D-series resolvins R-HSA-9018676
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Metabolism R-HSA-1430728
Innate Immune System R-HSA-168249
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Arachidonic acid metabolism R-HSA-2142753
Fatty acid metabolism R-HSA-8978868
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of D-series resolvins R-HSA-9018676
Immune System R-HSA-168256
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Neutrophil degranulation R-HSA-6798695
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Biosynthesis of protectins R-HSA-9018681
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Innate Immune System R-HSA-168249
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of protectins R-HSA-9018681
Metabolism R-HSA-1430728
Biosynthesis of D-series resolvins R-HSA-9018676
Metabolism of lipids R-HSA-556833
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Fatty acid metabolism R-HSA-8978868
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Innate Immune System R-HSA-168249
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of D-series resolvins R-HSA-9018676
Neutrophil degranulation R-HSA-6798695
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Biosynthesis of protectins R-HSA-9018681
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Metabolism of lipids R-HSA-556833
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Fatty acid metabolism R-HSA-8978868
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Metabolism R-HSA-1430728
Immune System R-HSA-168256
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Fatty acid metabolism R-HSA-8978868
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Metabolism R-HSA-1430728
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Immune System R-HSA-168256
Biosynthesis of D-series resolvins R-HSA-9018676
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Innate Immune System R-HSA-168249
Biosynthesis of protectins R-HSA-9018681
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Neutrophil degranulation R-HSA-6798695
Metabolism of lipids R-HSA-556833
Arachidonic acid metabolism R-HSA-2142753
Fatty acid metabolism R-HSA-8978868
Immune System R-HSA-168256
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of protectins R-HSA-9018681
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Biosynthesis of D-series resolvins R-HSA-9018676
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Biosynthesis of protectins R-HSA-9018681
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Metabolism of lipids R-HSA-556833
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Innate Immune System R-HSA-168249
Biosynthesis of D-series resolvins R-HSA-9018676
Neutrophil degranulation R-HSA-6798695
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Arachidonic acid metabolism R-HSA-2142753
Immune System R-HSA-168256
Metabolism R-HSA-1430728
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Fatty acid metabolism R-HSA-8978868
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Biosynthesis of D-series resolvins R-HSA-9018676
Metabolism R-HSA-1430728
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Fatty acid metabolism R-HSA-8978868
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Metabolism of lipids R-HSA-556833
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Immune System R-HSA-168256
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Neutrophil degranulation R-HSA-6798695
Biosynthesis of protectins R-HSA-9018681
Innate Immune System R-HSA-168249
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Fatty acid metabolism R-HSA-8978868
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Neutrophil degranulation R-HSA-6798695
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Immune System R-HSA-168256
Biosynthesis of D-series resolvins R-HSA-9018676
Metabolism R-HSA-1430728
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Metabolism of lipids R-HSA-556833
Innate Immune System R-HSA-168249
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Biosynthesis of protectins R-HSA-9018681
Arachidonic acid metabolism R-HSA-2142753
Fatty acid metabolism R-HSA-8978868
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Innate Immune System R-HSA-168249
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Biosynthesis of protectins R-HSA-9018681
Metabolism R-HSA-1430728
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Metabolism of lipids R-HSA-556833
Biosynthesis of D-series resolvins R-HSA-9018676

Expression Atlas ENSG00000111144
NCBI gene (formerly Entrezgene) 4048
GeneCards 6710
HGNC Symbol HGNC:6710
MIM gene 151570
UniProtKB Gene Name P09960
WikiGene 4048
Gene: MMP9
Ensembl ID : ENSG00000100985
Description: matrix metallopeptidase 9
Gene Synonyms: CLG4B
3 APIs:
216 Possible Orthologues:

Collagen formation R-HSA-1474290
EPH-Ephrin signaling R-HSA-2682334
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Extracellular matrix organization R-HSA-1474244
Developmental Biology R-HSA-1266738
Innate Immune System R-HSA-168249
Collagen degradation R-HSA-1442490
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Extra-nuclear estrogen signaling R-HSA-9009391
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Interleukins R-HSA-449147
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Signaling by SCF-KIT R-HSA-1433557
ESR-mediated signaling R-HSA-8939211
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nervous system development R-HSA-9675108
EPH-Ephrin signaling R-HSA-2682334
Activation of Matrix Metalloproteinases R-HSA-1592389
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by SCF-KIT R-HSA-1433557
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Collagen formation R-HSA-1474290
Degradation of the extracellular matrix R-HSA-1474228
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Collagen degradation R-HSA-1442490
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Extracellular matrix organization R-HSA-1474244
ESR-mediated signaling R-HSA-8939211
Extra-nuclear estrogen signaling R-HSA-9009391
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Collagen degradation R-HSA-1442490
Neutrophil degranulation R-HSA-6798695
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Cytokine Signaling in Immune system R-HSA-1280215
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
Nervous system development R-HSA-9675108
Extra-nuclear estrogen signaling R-HSA-9009391
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Immune System R-HSA-168256
Collagen formation R-HSA-1474290
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
ESR-mediated signaling R-HSA-8939211
Degradation of the extracellular matrix R-HSA-1474228
Signaling by Interleukins R-HSA-449147
Signaling by SCF-KIT R-HSA-1433557
EPH-Ephrin signaling R-HSA-2682334
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Signaling by Nuclear Receptors R-HSA-9006931
Signal Transduction R-HSA-162582
Degradation of the extracellular matrix R-HSA-1474228
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
EPH-Ephrin signaling R-HSA-2682334
Cytokine Signaling in Immune system R-HSA-1280215
ESR-mediated signaling R-HSA-8939211
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
Collagen formation R-HSA-1474290
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Extracellular matrix organization R-HSA-1474244
Nervous system development R-HSA-9675108
Collagen degradation R-HSA-1442490
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Extra-nuclear estrogen signaling R-HSA-9009391
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Interleukins R-HSA-449147
Activation of Matrix Metalloproteinases R-HSA-1592389
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Signaling by SCF-KIT R-HSA-1433557
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Immune System R-HSA-168256
Extra-nuclear estrogen signaling R-HSA-9009391
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by SCF-KIT R-HSA-1433557
ESR-mediated signaling R-HSA-8939211
Signaling by Nuclear Receptors R-HSA-9006931
Immune System R-HSA-168256
EPH-Ephrin signaling R-HSA-2682334
Axon guidance R-HSA-422475
Neutrophil degranulation R-HSA-6798695
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Nervous system development R-HSA-9675108
Cytokine Signaling in Immune system R-HSA-1280215
Collagen formation R-HSA-1474290
Signal Transduction R-HSA-162582
Collagen degradation R-HSA-1442490
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
Innate Immune System R-HSA-168249
Collagen degradation R-HSA-1442490
Signal Transduction R-HSA-162582
Degradation of the extracellular matrix R-HSA-1474228
Immune System R-HSA-168256
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Nuclear Receptors R-HSA-9006931
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
EPH-Ephrin signaling R-HSA-2682334
Extra-nuclear estrogen signaling R-HSA-9009391
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Axon guidance R-HSA-422475
Neutrophil degranulation R-HSA-6798695
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nervous system development R-HSA-9675108
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Activation of Matrix Metalloproteinases R-HSA-1592389
ESR-mediated signaling R-HSA-8939211
Signaling by Interleukins R-HSA-449147
Extracellular matrix organization R-HSA-1474244
Collagen formation R-HSA-1474290
Developmental Biology R-HSA-1266738
Signaling by SCF-KIT R-HSA-1433557
Signaling by Interleukins R-HSA-449147
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signal Transduction R-HSA-162582
Collagen degradation R-HSA-1442490
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by SCF-KIT R-HSA-1433557
ESR-mediated signaling R-HSA-8939211
EPH-Ephrin signaling R-HSA-2682334
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Developmental Biology R-HSA-1266738
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Signaling by Nuclear Receptors R-HSA-9006931
Cytokine Signaling in Immune system R-HSA-1280215
Collagen formation R-HSA-1474290
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Axon guidance R-HSA-422475
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Nuclear Receptors R-HSA-9006931
Developmental Biology R-HSA-1266738
EPH-ephrin mediated repulsion of cells R-HSA-3928665
ESR-mediated signaling R-HSA-8939211
Signal Transduction R-HSA-162582
Extracellular matrix organization R-HSA-1474244
Signaling by Interleukins R-HSA-449147
Collagen formation R-HSA-1474290
Extra-nuclear estrogen signaling R-HSA-9009391
EPH-Ephrin signaling R-HSA-2682334
Signaling by SCF-KIT R-HSA-1433557
Axon guidance R-HSA-422475
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Degradation of the extracellular matrix R-HSA-1474228
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Activation of Matrix Metalloproteinases R-HSA-1592389
Collagen degradation R-HSA-1442490
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Degradation of the extracellular matrix R-HSA-1474228
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
Innate Immune System R-HSA-168249
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Interleukins R-HSA-449147
Nervous system development R-HSA-9675108
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
ESR-mediated signaling R-HSA-8939211
EPH-Ephrin signaling R-HSA-2682334
Cytokine Signaling in Immune system R-HSA-1280215
Activation of Matrix Metalloproteinases R-HSA-1592389
Neutrophil degranulation R-HSA-6798695
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Collagen formation R-HSA-1474290
Signaling by SCF-KIT R-HSA-1433557
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Collagen degradation R-HSA-1442490
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
EPH-Ephrin signaling R-HSA-2682334
Signaling by SCF-KIT R-HSA-1433557
Collagen degradation R-HSA-1442490
Signaling by Nuclear Receptors R-HSA-9006931
Extracellular matrix organization R-HSA-1474244
Neutrophil degranulation R-HSA-6798695
Extra-nuclear estrogen signaling R-HSA-9009391
Immune System R-HSA-168256
Activation of Matrix Metalloproteinases R-HSA-1592389
Innate Immune System R-HSA-168249
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Degradation of the extracellular matrix R-HSA-1474228
Signaling by Interleukins R-HSA-449147
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
ESR-mediated signaling R-HSA-8939211
Nervous system development R-HSA-9675108
Collagen formation R-HSA-1474290

Expression Atlas ENSG00000100985
NCBI gene (formerly Entrezgene) 4318
GeneCards 7176
HGNC Symbol HGNC:7176
MIM gene 120361
MIM morbid 613073
UniProtKB Gene Name P14780
WikiGene 4318