Gene: NCSTN
Ensembl ID : ENSG00000162736
Description: nicastrin
Gene Synonyms: APH2,KIAA0253
5 APIs:
204 Possible Orthologues:

Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Death Receptor Signaling R-HSA-73887
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH3 R-HSA-9012852
Nervous system development R-HSA-9675108
Amyloid fiber formation R-HSA-977225
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 in Cancer R-HSA-2644603
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulated proteolysis of p75NTR R-HSA-193692
Disease R-HSA-1643685
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 R-HSA-1980143
p75 NTR receptor-mediated signalling R-HSA-193704
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Neutrophil degranulation R-HSA-6798695
EPH-Ephrin signaling R-HSA-2682334
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Immune System R-HSA-168256
Signaling by ERBB4 R-HSA-1236394
Innate Immune System R-HSA-168249
Axon guidance R-HSA-422475
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH4 R-HSA-9013694
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by ERBB4 R-HSA-1236394
Neutrophil degranulation R-HSA-6798695
Amyloid fiber formation R-HSA-977225
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 in Cancer R-HSA-2644603
Death Receptor Signaling R-HSA-73887
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Developmental Biology R-HSA-1266738
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Innate Immune System R-HSA-168249
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Immune System R-HSA-168256
Nuclear signaling by ERBB4 R-HSA-1251985
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH3 R-HSA-9012852
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Nervous system development R-HSA-9675108
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH3 R-HSA-9012852
EPH-Ephrin signaling R-HSA-2682334
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 R-HSA-1980143
Degradation of the extracellular matrix R-HSA-1474228
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Neutrophil degranulation R-HSA-6798695
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
p75 NTR receptor-mediated signalling R-HSA-193704
Noncanonical activation of NOTCH3 R-HSA-9017802
Regulated proteolysis of p75NTR R-HSA-193692
Death Receptor Signaling R-HSA-73887
Signaling by ERBB4 R-HSA-1236394
Amyloid fiber formation R-HSA-977225
Disease R-HSA-1643685
Innate Immune System R-HSA-168249
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
Metabolism of proteins R-HSA-392499
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH2 R-HSA-1980145
Immune System R-HSA-168256
Signaling by NOTCH1 in Cancer R-HSA-2644603
Axon guidance R-HSA-422475
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Axon guidance R-HSA-422475
NRIF signals cell death from the nucleus R-HSA-205043
Signal Transduction R-HSA-162582
p75 NTR receptor-mediated signalling R-HSA-193704
Degradation of the extracellular matrix R-HSA-1474228
Disease R-HSA-1643685
Neutrophil degranulation R-HSA-6798695
Signaling by ERBB4 R-HSA-1236394
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
Metabolism of proteins R-HSA-392499
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH4 R-HSA-9013694
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH2 R-HSA-1980145
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 R-HSA-1980143
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Extracellular matrix organization R-HSA-1474244
Developmental Biology R-HSA-1266738
Regulated proteolysis of p75NTR R-HSA-193692
p75 NTR receptor-mediated signalling R-HSA-193704
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Noncanonical activation of NOTCH3 R-HSA-9017802
Regulated proteolysis of p75NTR R-HSA-193692
Neutrophil degranulation R-HSA-6798695
Nervous system development R-HSA-9675108
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NRIF signals cell death from the nucleus R-HSA-205043
Death Receptor Signaling R-HSA-73887
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 R-HSA-1980143
Metabolism of proteins R-HSA-392499
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Developmental Biology R-HSA-1266738
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH4 R-HSA-9013694
Nuclear signaling by ERBB4 R-HSA-1251985
Immune System R-HSA-168256
EPH-Ephrin signaling R-HSA-2682334
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH2 R-HSA-1980145
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
Signaling by ERBB4 R-HSA-1236394
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Amyloid fiber formation R-HSA-977225
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Degradation of the extracellular matrix R-HSA-1474228
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 in Cancer R-HSA-2644603
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
Regulated proteolysis of p75NTR R-HSA-193692
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-Ephrin signaling R-HSA-2682334
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by ERBB4 R-HSA-1236394
Metabolism of proteins R-HSA-392499
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH R-HSA-157118
Axon guidance R-HSA-422475
Amyloid fiber formation R-HSA-977225
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH4 R-HSA-9013694
Developmental Biology R-HSA-1266738
Degradation of the extracellular matrix R-HSA-1474228
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neutrophil degranulation R-HSA-6798695
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Noncanonical activation of NOTCH3 R-HSA-9017802
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH3 R-HSA-9012852
Nuclear signaling by ERBB4 R-HSA-1251985
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 R-HSA-1980143
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Innate Immune System R-HSA-168249
Nervous system development R-HSA-9675108
p75 NTR receptor-mediated signalling R-HSA-193704
Death Receptor Signaling R-HSA-73887
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
EPH-Ephrin signaling R-HSA-2682334
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
Signaling by NOTCH R-HSA-157118
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
Degradation of the extracellular matrix R-HSA-1474228
Signaling by NOTCH2 R-HSA-1980145
NRIF signals cell death from the nucleus R-HSA-205043
Amyloid fiber formation R-HSA-977225
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulated proteolysis of p75NTR R-HSA-193692
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH3 R-HSA-9012852
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Extracellular matrix organization R-HSA-1474244
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Degradation of the extracellular matrix R-HSA-1474228
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Immune System R-HSA-168256
p75 NTR receptor-mediated signalling R-HSA-193704
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 in Cancer R-HSA-2644603
Amyloid fiber formation R-HSA-977225
Developmental Biology R-HSA-1266738
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Metabolism of proteins R-HSA-392499
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH2 R-HSA-1980145
Nervous system development R-HSA-9675108
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Noncanonical activation of NOTCH3 R-HSA-9017802
Axon guidance R-HSA-422475
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
NRIF signals cell death from the nucleus R-HSA-205043
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
Degradation of the extracellular matrix R-HSA-1474228
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
p75 NTR receptor-mediated signalling R-HSA-193704
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH3 R-HSA-9012852
Death Receptor Signaling R-HSA-73887
Innate Immune System R-HSA-168249
Noncanonical activation of NOTCH3 R-HSA-9017802
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by ERBB4 R-HSA-1236394
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH4 R-HSA-9013694
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Extracellular matrix organization R-HSA-1474244
Neutrophil degranulation R-HSA-6798695
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Disease R-HSA-1643685
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signal Transduction R-HSA-162582
NRIF signals cell death from the nucleus R-HSA-205043
Amyloid fiber formation R-HSA-977225
Nuclear signaling by ERBB4 R-HSA-1251985
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH2 R-HSA-1980145
Axon guidance R-HSA-422475
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Innate Immune System R-HSA-168249
Metabolism of proteins R-HSA-392499
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NRIF signals cell death from the nucleus R-HSA-205043
Neutrophil degranulation R-HSA-6798695
Degradation of the extracellular matrix R-HSA-1474228
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 R-HSA-1980143
Signaling by ERBB4 R-HSA-1236394
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Disease R-HSA-1643685
Noncanonical activation of NOTCH3 R-HSA-9017802
EPH-ephrin mediated repulsion of cells R-HSA-3928665
p75 NTR receptor-mediated signalling R-HSA-193704
Nervous system development R-HSA-9675108
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
Amyloid fiber formation R-HSA-977225
Nuclear signaling by ERBB4 R-HSA-1251985
Regulated proteolysis of p75NTR R-HSA-193692
Immune System R-HSA-168256
Signaling by NOTCH4 R-HSA-9013694
Extracellular matrix organization R-HSA-1474244
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH4 R-HSA-9013694
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Noncanonical activation of NOTCH3 R-HSA-9017802
Death Receptor Signaling R-HSA-73887
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Amyloid fiber formation R-HSA-977225
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Degradation of the extracellular matrix R-HSA-1474228
p75 NTR receptor-mediated signalling R-HSA-193704
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
Signaling by ERBB4 R-HSA-1236394
Metabolism of proteins R-HSA-392499
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Developmental Biology R-HSA-1266738
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
Neutrophil degranulation R-HSA-6798695
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Nuclear signaling by ERBB4 R-HSA-1251985
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 in Cancer R-HSA-2644603

Expression Atlas ENSG00000162736
LRG display in Ensembl gene LRG_223
NCBI gene (formerly Entrezgene) 23385
GeneCards 17091
HGNC Symbol HGNC:17091
MIM gene 605254
MIM morbid 142690
UniProtKB Gene Name Q92542
WikiGene 23385
Gene: MME
Ensembl ID : ENSG00000196549
Description: membrane metalloendopeptidase
Gene Synonyms: CALLA,CD10,NEP
3 APIs:
236 Possible Orthologues:

Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Physiological factors R-HSA-5578768
Innate Immune System R-HSA-168249
Peptide hormone metabolism R-HSA-2980736
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Muscle contraction R-HSA-397014
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Cardiac conduction R-HSA-5576891
Peptide hormone metabolism R-HSA-2980736
Physiological factors R-HSA-5578768
Immune System R-HSA-168256
Muscle contraction R-HSA-397014
Innate Immune System R-HSA-168249
Cardiac conduction R-HSA-5576891
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of proteins R-HSA-392499
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Physiological factors R-HSA-5578768
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Muscle contraction R-HSA-397014
Immune System R-HSA-168256
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Neutrophil degranulation R-HSA-6798695
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Cardiac conduction R-HSA-5576891
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Physiological factors R-HSA-5578768
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Physiological factors R-HSA-5578768
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Peptide hormone metabolism R-HSA-2980736
Neutrophil degranulation R-HSA-6798695
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768
Peptide hormone metabolism R-HSA-2980736
Muscle contraction R-HSA-397014
Muscle contraction R-HSA-397014
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Physiological factors R-HSA-5578768
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Neutrophil degranulation R-HSA-6798695
Cardiac conduction R-HSA-5576891
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Immune System R-HSA-168256
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Peptide hormone metabolism R-HSA-2980736
Neutrophil degranulation R-HSA-6798695
Physiological factors R-HSA-5578768
Innate Immune System R-HSA-168249
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Cardiac conduction R-HSA-5576891

Expression Atlas ENSG00000196549
NCBI gene (formerly Entrezgene) 4311
GeneCards 7154
HGNC Symbol HGNC:7154
MIM gene 120520
MIM morbid 617018
UniProtKB Gene Name Q3KQS6
WikiGene 4311
Gene: ADRM1
Ensembl ID : ENSG00000130706
Description: ADRM1 26S proteasome ubiquitin receptor
Gene Synonyms: ARM1,GP110,PSMD16,RPN13
5 APIs:
261 Possible Orthologues:

Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
Deubiquitination R-HSA-5688426
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
UCH proteinases R-HSA-5689603
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592

Expression Atlas ENSG00000130706
NCBI gene (formerly Entrezgene) 11047
GeneCards 15759
HGNC Symbol HGNC:15759
MIM gene 610650
UniProtKB Gene Name Q16186
WikiGene 11047
Gene: CTSK
Ensembl ID : ENSG00000143387
Description: cathepsin K
Gene Synonyms: CTSO,CTSO2,PKND,PYCD
2 APIs:
246 Possible Orthologues:

Innate Immune System R-HSA-168249
Collagen degradation R-HSA-1442490
RNA Polymerase II Transcription R-HSA-73857
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
MHC class II antigen presentation R-HSA-2132295
Trafficking and processing of endosomal TLR R-HSA-1679131
Generic Transcription Pathway R-HSA-212436
Toll-like Receptor Cascades R-HSA-168898
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of the extracellular matrix R-HSA-1474228
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Collagen degradation R-HSA-1442490
Gene expression (Transcription) R-HSA-74160
Degradation of the extracellular matrix R-HSA-1474228
Toll-like Receptor Cascades R-HSA-168898
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Trafficking and processing of endosomal TLR R-HSA-1679131
Activation of Matrix Metalloproteinases R-HSA-1592389
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
Extracellular matrix organization R-HSA-1474244
MHC class II antigen presentation R-HSA-2132295
Transcriptional regulation by RUNX1 R-HSA-8878171
RNA Polymerase II Transcription R-HSA-73857
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Gene expression (Transcription) R-HSA-74160
Collagen degradation R-HSA-1442490
Activation of Matrix Metalloproteinases R-HSA-1592389
Immune System R-HSA-168256
Trafficking and processing of endosomal TLR R-HSA-1679131
Degradation of the extracellular matrix R-HSA-1474228
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Adaptive Immune System R-HSA-1280218
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX1 R-HSA-8878171
MHC class II antigen presentation R-HSA-2132295
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Immune System R-HSA-168256
Degradation of the extracellular matrix R-HSA-1474228
Trafficking and processing of endosomal TLR R-HSA-1679131
Innate Immune System R-HSA-168249
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
Collagen degradation R-HSA-1442490
Extracellular matrix organization R-HSA-1474244
Adaptive Immune System R-HSA-1280218
Generic Transcription Pathway R-HSA-212436
Toll-like Receptor Cascades R-HSA-168898
MHC class II antigen presentation R-HSA-2132295
Activation of Matrix Metalloproteinases R-HSA-1592389
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Collagen degradation R-HSA-1442490
Adaptive Immune System R-HSA-1280218
Toll-like Receptor Cascades R-HSA-168898
Gene expression (Transcription) R-HSA-74160
Activation of Matrix Metalloproteinases R-HSA-1592389
Immune System R-HSA-168256
Degradation of the extracellular matrix R-HSA-1474228
MHC class II antigen presentation R-HSA-2132295
Trafficking and processing of endosomal TLR R-HSA-1679131
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX1 R-HSA-8878171
Extracellular matrix organization R-HSA-1474244
Generic Transcription Pathway R-HSA-212436
Innate Immune System R-HSA-168249
Collagen degradation R-HSA-1442490
Degradation of the extracellular matrix R-HSA-1474228
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
MHC class II antigen presentation R-HSA-2132295
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Activation of Matrix Metalloproteinases R-HSA-1592389
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
Trafficking and processing of endosomal TLR R-HSA-1679131
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Collagen degradation R-HSA-1442490
Trafficking and processing of endosomal TLR R-HSA-1679131
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Generic Transcription Pathway R-HSA-212436
Activation of Matrix Metalloproteinases R-HSA-1592389
Toll-like Receptor Cascades R-HSA-168898
MHC class II antigen presentation R-HSA-2132295
Transcriptional regulation by RUNX1 R-HSA-8878171
Adaptive Immune System R-HSA-1280218
Extracellular matrix organization R-HSA-1474244
RNA Polymerase II Transcription R-HSA-73857
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Trafficking and processing of endosomal TLR R-HSA-1679131
Degradation of the extracellular matrix R-HSA-1474228
RNA Polymerase II Transcription R-HSA-73857
MHC class II antigen presentation R-HSA-2132295
Adaptive Immune System R-HSA-1280218
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of Matrix Metalloproteinases R-HSA-1592389
Collagen degradation R-HSA-1442490
MHC class II antigen presentation R-HSA-2132295
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
Generic Transcription Pathway R-HSA-212436
Degradation of the extracellular matrix R-HSA-1474228
Activation of Matrix Metalloproteinases R-HSA-1592389
RNA Polymerase II Transcription R-HSA-73857
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Trafficking and processing of endosomal TLR R-HSA-1679131
Collagen degradation R-HSA-1442490
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Innate Immune System R-HSA-168249
Degradation of the extracellular matrix R-HSA-1474228
RNA Polymerase II Transcription R-HSA-73857
Toll-like Receptor Cascades R-HSA-168898
MHC class II antigen presentation R-HSA-2132295
Collagen degradation R-HSA-1442490
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of Matrix Metalloproteinases R-HSA-1592389
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Immune System R-HSA-168256
Extracellular matrix organization R-HSA-1474244
Trafficking and processing of endosomal TLR R-HSA-1679131
Adaptive Immune System R-HSA-1280218

Expression Atlas ENSG00000143387
NCBI gene (formerly Entrezgene) 1513
GeneCards 2536
HGNC Symbol HGNC:2536
MIM gene 601105
MIM morbid 265800
UniProtKB Gene Name Q5QP40
WikiGene 1513
Gene: ACE
Ensembl ID : ENSG00000159640
Description: angiotensin I converting enzyme
Gene Synonyms: ACE1,CD143,DCP1
18 APIs:
92 Possible Orthologues:

Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736

Expression Atlas ENSG00000159640
NCBI gene (formerly Entrezgene) 1636
GeneCards 2707
HGNC Symbol HGNC:2707
MIM gene 106180
MIM morbid 614519
UniProtKB Gene Name P12821
WikiGene 1636
Gene: PSEN2
Ensembl ID : ENSG00000143801
Description: presenilin 2
Gene Synonyms: AD3L,AD4,E5-1,PS-2,PS2,STM2
5 APIs:
205 Possible Orthologues:

NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH4 R-HSA-9013694
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
Nervous system development R-HSA-9675108
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH3 R-HSA-9012852
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Nuclear signaling by ERBB4 R-HSA-1251985
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by ERBB4 R-HSA-1236394
Disease R-HSA-1643685
Noncanonical activation of NOTCH3 R-HSA-9017802
EPH-Ephrin signaling R-HSA-2682334
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Axon guidance R-HSA-422475
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signal Transduction R-HSA-162582
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 R-HSA-1980143
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Nervous system development R-HSA-9675108
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Axon guidance R-HSA-422475
Signaling by NOTCH3 R-HSA-9012852
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH2 R-HSA-1980145
p75 NTR receptor-mediated signalling R-HSA-193704
Death Receptor Signaling R-HSA-73887
EPH-Ephrin signaling R-HSA-2682334
Noncanonical activation of NOTCH3 R-HSA-9017802
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Developmental Biology R-HSA-1266738
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NRIF signals cell death from the nucleus R-HSA-205043
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH4 R-HSA-9013694
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH2 R-HSA-1980145
Nuclear signaling by ERBB4 R-HSA-1251985
Signal Transduction R-HSA-162582
EPH-Ephrin signaling R-HSA-2682334
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 R-HSA-1980143
Signaling by ERBB4 R-HSA-1236394
Noncanonical activation of NOTCH3 R-HSA-9017802
Axon guidance R-HSA-422475
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH3 R-HSA-9012852
NRIF signals cell death from the nucleus R-HSA-205043
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Death Receptor Signaling R-HSA-73887
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
p75 NTR receptor-mediated signalling R-HSA-193704
Developmental Biology R-HSA-1266738
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by ERBB4 R-HSA-1236394
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH2 R-HSA-1980145
Noncanonical activation of NOTCH3 R-HSA-9017802
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Nervous system development R-HSA-9675108
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 in Cancer R-HSA-2644603
EPH-Ephrin signaling R-HSA-2682334
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
p75 NTR receptor-mediated signalling R-HSA-193704
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH3 R-HSA-9012852
EPH-Ephrin signaling R-HSA-2682334
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Noncanonical activation of NOTCH3 R-HSA-9017802
Regulated proteolysis of p75NTR R-HSA-193692
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Axon guidance R-HSA-422475
Signaling by ERBB4 R-HSA-1236394
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH R-HSA-157118
NRIF signals cell death from the nucleus R-HSA-205043
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH2 R-HSA-1980145
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
Nuclear signaling by ERBB4 R-HSA-1251985
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Disease R-HSA-1643685
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nuclear signaling by ERBB4 R-HSA-1251985
Nervous system development R-HSA-9675108
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH3 R-HSA-9012852
Signaling by ERBB4 R-HSA-1236394
Axon guidance R-HSA-422475
Noncanonical activation of NOTCH3 R-HSA-9017802
p75 NTR receptor-mediated signalling R-HSA-193704
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH R-HSA-157118
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH2 R-HSA-1980145
Signal Transduction R-HSA-162582
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Death Receptor Signaling R-HSA-73887
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 in Cancer R-HSA-2644603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 in Cancer R-HSA-2644603
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Noncanonical activation of NOTCH3 R-HSA-9017802
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH3 R-HSA-9012852
Disease R-HSA-1643685
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Developmental Biology R-HSA-1266738
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 R-HSA-1980143
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by ERBB4 R-HSA-1236394
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Nuclear signaling by ERBB4 R-HSA-1251985
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Axon guidance R-HSA-422475
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EPH-Ephrin signaling R-HSA-2682334
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 in Cancer R-HSA-2644603
Noncanonical activation of NOTCH3 R-HSA-9017802
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH3 R-HSA-9012852
Nervous system development R-HSA-9675108
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Death Receptor Signaling R-HSA-73887
Signal Transduction R-HSA-162582
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH1 R-HSA-1980143
p75 NTR receptor-mediated signalling R-HSA-193704
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by ERBB4 R-HSA-1236394
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 in Cancer R-HSA-2644603
p75 NTR receptor-mediated signalling R-HSA-193704
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Nervous system development R-HSA-9675108
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 R-HSA-1980143
Signaling by ERBB4 R-HSA-1236394
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Signaling by NOTCH3 R-HSA-9012852
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH2 R-HSA-1980145
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Developmental Biology R-HSA-1266738
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Nuclear signaling by ERBB4 R-HSA-1251985
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 in Cancer R-HSA-2644603
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
NRIF signals cell death from the nucleus R-HSA-205043
Axon guidance R-HSA-422475
Signaling by NOTCH2 R-HSA-1980145
Disease R-HSA-1643685
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by ERBB4 R-HSA-1236394
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
p75 NTR receptor-mediated signalling R-HSA-193704
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 R-HSA-1980143
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH4 R-HSA-9013694
Nuclear signaling by ERBB4 R-HSA-1251985
Death Receptor Signaling R-HSA-73887
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096

Expression Atlas ENSG00000143801
LRG display in Ensembl gene LRG_225
NCBI gene (formerly Entrezgene) 5664
GeneCards 9509
HGNC Symbol HGNC:9509
MIM gene 600759
MIM morbid 613697
UniProtKB Gene Name P49810
WikiGene 5664
Gene: PSMC5
Ensembl ID : ENSG00000087191
Description: proteasome 26S subunit, ATPase 5
Gene Synonyms: P45,P45/SUG,RPT6,S8,SUG-1,SUG1,TBP10,TRIP1
5 APIs:
219 Possible Orthologues:

G1/S Transition R-HSA-69206
G2/M Checkpoints R-HSA-69481
Hedgehog 'on' state R-HSA-5632684
S Phase R-HSA-69242
Degradation of DVL R-HSA-4641258
Signaling by NOTCH R-HSA-157118
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TCR signaling R-HSA-202403
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK family signaling cascades R-HSA-5683057
UCH proteinases R-HSA-5689603
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Deubiquitination R-HSA-5688426
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of amino acids and derivatives R-HSA-71291
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular responses to stimuli R-HSA-8953897
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
ABC-family proteins mediated transport R-HSA-382556
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle, Mitotic R-HSA-69278
Cytokine Signaling in Immune system R-HSA-1280215
Generic Transcription Pathway R-HSA-212436
Degradation of DVL R-HSA-4641258
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of Apoptosis R-HSA-169911
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK6/MAPK4 signaling R-HSA-5687128
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH4 R-HSA-9013694
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
Cell Cycle R-HSA-1640170
Programmed Cell Death R-HSA-5357801
Regulation of RAS by GAPs R-HSA-5658442
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog 'on' state R-HSA-5632684
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by ROBO receptors R-HSA-376176
Mitotic Anaphase R-HSA-68882
Regulation of RUNX3 expression and activity R-HSA-8941858
Negative regulation of NOTCH4 signaling R-HSA-9604323
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX2 expression and activity R-HSA-8939902
Beta-catenin independent WNT signaling R-HSA-3858494
Apoptosis R-HSA-109581
p53-Independent DNA Damage Response R-HSA-69610
Degradation of beta-catenin by the destruction complex R-HSA-195253
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
Cyclin E associated events during G1/S transition R-HSA-69202
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 signaling R-HSA-9020702
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by the B Cell Receptor (BCR) R-HSA-983705
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular response to chemical stress R-HSA-9711123
Orc1 removal from chromatin R-HSA-68949
Metabolism of RNA R-HSA-8953854
Transcriptional regulation by RUNX2 R-HSA-8878166
PIP3 activates AKT signaling R-HSA-1257604
Hh mutants are degraded by ERAD R-HSA-5362768
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ABC transporter disorders R-HSA-5619084
ER-Phagosome pathway R-HSA-1236974
MAPK1/MAPK3 signaling R-HSA-5684996
Host Interactions of HIV factors R-HSA-162909
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX1 R-HSA-8878171
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stress R-HSA-2262752
HIV Infection R-HSA-162906
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by NOTCH R-HSA-157118
Stabilization of p53 R-HSA-69541
Immune System R-HSA-168256
Metabolism of proteins R-HSA-392499
Developmental Biology R-HSA-1266738
Innate Immune System R-HSA-168249
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants abrogate ligand secretion R-HSA-5387390
S Phase R-HSA-69242
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle Checkpoints R-HSA-69620
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
PTEN Regulation R-HSA-6807070
Switching of origins to a post-replicative state R-HSA-69052
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Asymmetric localization of PCP proteins R-HSA-4608870
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication Pre-Initiation R-HSA-69002
Infectious disease R-HSA-5663205
PCP/CE pathway R-HSA-4086400
FCERI mediated NF-kB activation R-HSA-2871837
Activation of NF-kappaB in B cells R-HSA-1169091
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mitotic cell cycle R-HSA-453276
Signaling by WNT R-HSA-195721
Metabolism of polyamines R-HSA-351202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ub-specific processing proteases R-HSA-5689880
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by Interleukins R-HSA-449147
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Mitotic G2-G2/M phases R-HSA-453274
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog 'off' state R-HSA-5610787
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
Class I MHC mediated antigen processing & presentation R-HSA-983169
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Deubiquitination R-HSA-5688426
Programmed Cell Death R-HSA-5357801
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nuclear events mediated by NFE2L2 R-HSA-9759194
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Signaling by Interleukins R-HSA-449147
HIV Infection R-HSA-162906
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism R-HSA-1430728
Ub-specific processing proteases R-HSA-5689880
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'off' state R-HSA-5610787
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle R-HSA-1640170
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
Transport of small molecules R-HSA-382551
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin E associated events during G1/S transition R-HSA-69202
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream TCR signaling R-HSA-202424
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
TCR signaling R-HSA-202403
Synthesis of DNA R-HSA-69239
Signaling by NOTCH R-HSA-157118
Cellular responses to stress R-HSA-2262752
FCERI mediated NF-kB activation R-HSA-2871837
Beta-catenin independent WNT signaling R-HSA-3858494
Neddylation R-HSA-8951664
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Gene expression (Transcription) R-HSA-74160
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Post-translational protein modification R-HSA-597592
p53-Dependent G1 DNA Damage Response R-HSA-69563
PCP/CE pathway R-HSA-4086400
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
DNA Replication R-HSA-69306
G2/M Transition R-HSA-69275
Stabilization of p53 R-HSA-69541
Signaling by WNT R-HSA-195721
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing-Cross presentation R-HSA-1236975
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of AXIN R-HSA-4641257
Disorders of transmembrane transporters R-HSA-5619115
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
G2/M Checkpoints R-HSA-69481
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mitotic cell cycle R-HSA-453276
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of RNA R-HSA-8953854
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular response to hypoxia R-HSA-1234174
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'on' state R-HSA-5632684
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
ABC-family proteins mediated transport R-HSA-382556
Regulation of RAS by GAPs R-HSA-5658442
Immune System R-HSA-168256
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stimuli R-HSA-8953897
ER-Phagosome pathway R-HSA-1236974
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Class I MHC mediated antigen processing & presentation R-HSA-983169
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Mitotic Anaphase R-HSA-68882
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 family signaling R-HSA-446652
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Adaptive Immune System R-HSA-1280218
Vif-mediated degradation of APOBEC3G R-HSA-180585
Apoptosis R-HSA-109581
G1/S Transition R-HSA-69206
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by ROBO receptors R-HSA-376176
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of Apoptosis R-HSA-169911
Regulation of RUNX3 expression and activity R-HSA-8941858
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 signaling R-HSA-9020702
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of PTEN stability and activity R-HSA-8948751
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Generic Transcription Pathway R-HSA-212436
S Phase R-HSA-69242
Axon guidance R-HSA-422475
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Mitotic G2-G2/M phases R-HSA-453274
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic G1 phase and G1/S transition R-HSA-453279
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PIP3 activates AKT signaling R-HSA-1257604
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of DVL R-HSA-4641258
Nervous system development R-HSA-9675108
p53-Independent DNA Damage Response R-HSA-69610
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ABC-family proteins mediated transport R-HSA-382556
Infectious disease R-HSA-5663205
Metabolism R-HSA-1430728
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of RUNX3 expression and activity R-HSA-8941858
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Mitotic Metaphase and Anaphase R-HSA-2555396
ABC transporter disorders R-HSA-5619084
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Innate Immune System R-HSA-168249
G2/M Checkpoints R-HSA-69481
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RAS by GAPs R-HSA-5658442
RAF/MAP kinase cascade R-HSA-5673001
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by WNT R-HSA-195721
Stabilization of p53 R-HSA-69541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Activation of NF-kappaB in B cells R-HSA-1169091
Axon guidance R-HSA-422475
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hedgehog ligand biogenesis R-HSA-5358346
Cytokine Signaling in Immune system R-HSA-1280215
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX2 R-HSA-8878166
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RNA Polymerase II Transcription R-HSA-73857
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
CLEC7A (Dectin-1) signaling R-HSA-5607764
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream TCR signaling R-HSA-202424
Immune System R-HSA-168256
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MAPK family signaling cascades R-HSA-5683057
Nervous system development R-HSA-9675108
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Disorders of transmembrane transporters R-HSA-5619115
Regulation of mitotic cell cycle R-HSA-453276
Developmental Biology R-HSA-1266738
Hedgehog 'off' state R-HSA-5610787
Adaptive Immune System R-HSA-1280218
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PCP/CE pathway R-HSA-4086400
Assembly of the pre-replicative complex R-HSA-68867
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog 'on' state R-HSA-5632684
UCH proteinases R-HSA-5689603
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Independent DNA Damage Response R-HSA-69610
TCR signaling R-HSA-202403
Regulation of expression of SLITs and ROBOs R-HSA-9010553
C-type lectin receptors (CLRs) R-HSA-5621481
Generic Transcription Pathway R-HSA-212436
Deubiquitination R-HSA-5688426
Cellular responses to stress R-HSA-2262752
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX3 R-HSA-8878159
HIV Infection R-HSA-162906
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of polyamines R-HSA-351202
Cell Cycle Checkpoints R-HSA-69620
Defective CFTR causes cystic fibrosis R-HSA-5678895
Neddylation R-HSA-8951664
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of RNA R-HSA-8953854
Signaling by Hedgehog R-HSA-5358351
Separation of Sister Chromatids R-HSA-2467813
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S Transition R-HSA-69206
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Synthesis of DNA R-HSA-69239
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G2-G2/M phases R-HSA-453274
PTEN Regulation R-HSA-6807070
Regulation of Apoptosis R-HSA-169911
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of proteins R-HSA-392499
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication R-HSA-69306
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI2 by the proteasome R-HSA-5610783
Vif-mediated degradation of APOBEC3G R-HSA-180585
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stimuli R-HSA-8953897
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
Mitotic G1 phase and G1/S transition R-HSA-453279
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of amino acids and derivatives R-HSA-71291
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
S Phase R-HSA-69242
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Antigen processing-Cross presentation R-HSA-1236975
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI1 by the proteasome R-HSA-5610780
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to hypoxia R-HSA-1234174
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle, Mitotic R-HSA-69278
PIP3 activates AKT signaling R-HSA-1257604
Host Interactions of HIV factors R-HSA-162909
FCERI mediated NF-kB activation R-HSA-2871837
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX3 R-HSA-8878159
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of polyamines R-HSA-351202
Assembly of the pre-replicative complex R-HSA-68867
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
ER-Phagosome pathway R-HSA-1236974
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
Neddylation R-HSA-8951664
Degradation of AXIN R-HSA-4641257
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hedgehog 'on' state R-HSA-5632684
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
Synthesis of DNA R-HSA-69239
Degradation of DVL R-HSA-4641258
Hh mutants abrogate ligand secretion R-HSA-5387390
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
Signaling by NOTCH R-HSA-157118
Mitotic G2-G2/M phases R-HSA-453274
Metabolism R-HSA-1430728
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
Cell Cycle R-HSA-1640170
RAF/MAP kinase cascade R-HSA-5673001
Cellular response to hypoxia R-HSA-1234174
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by NOTCH4 R-HSA-9013694
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signal Transduction R-HSA-162582
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mitotic cell cycle R-HSA-453276
ABC transporter disorders R-HSA-5619084
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCR signaling R-HSA-202403
Regulation of Apoptosis R-HSA-169911
S Phase R-HSA-69242
Signaling by Interleukins R-HSA-449147
DNA Replication R-HSA-69306
Class I MHC mediated antigen processing & presentation R-HSA-983169
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
Cyclin E associated events during G1/S transition R-HSA-69202
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disease R-HSA-1643685
Signaling by Hedgehog R-HSA-5358351
Mitotic Metaphase and Anaphase R-HSA-2555396
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
HIV Infection R-HSA-162906
Degradation of GLI1 by the proteasome R-HSA-5610780
Programmed Cell Death R-HSA-5357801
Metabolism of RNA R-HSA-8953854
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transcriptional regulation by RUNX1 R-HSA-8878171
Post-translational protein modification R-HSA-597592
Regulation of RAS by GAPs R-HSA-5658442
Deubiquitination R-HSA-5688426
Adaptive Immune System R-HSA-1280218
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ub-specific processing proteases R-HSA-5689880
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
Signaling by ROBO receptors R-HSA-376176
Cell Cycle, Mitotic R-HSA-69278
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
M Phase R-HSA-68886
Hh mutants are degraded by ERAD R-HSA-5362768
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stimuli R-HSA-8953897
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by WNT R-HSA-195721
PCP/CE pathway R-HSA-4086400
PIP3 activates AKT signaling R-HSA-1257604
Cellular response to chemical stress R-HSA-9711123
Vpu mediated degradation of CD4 R-HSA-180534
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of PTEN stability and activity R-HSA-8948751
Stabilization of p53 R-HSA-69541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Transition R-HSA-69275
Regulation of expression of SLITs and ROBOs R-HSA-9010553
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of amino acids and derivatives R-HSA-71291
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Anaphase R-HSA-68882
Downstream TCR signaling R-HSA-202424
Host Interactions of HIV factors R-HSA-162909
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'off' state R-HSA-5610787
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing-Cross presentation R-HSA-1236975
FCERI mediated NF-kB activation R-HSA-2871837
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
KEAP1-NFE2L2 pathway R-HSA-9755511
Cytokine Signaling in Immune system R-HSA-1280215
Hedgehog ligand biogenesis R-HSA-5358346
C-type lectin receptors (CLRs) R-HSA-5621481
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Transport of small molecules R-HSA-382551
G1/S Transition R-HSA-69206
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX2 R-HSA-8878166
Interleukin-1 signaling R-HSA-9020702
Innate Immune System R-HSA-168249
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
PCP/CE pathway R-HSA-4086400
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
Mitotic G1 phase and G1/S transition R-HSA-453279
TCR signaling R-HSA-202403
p53-Dependent G1 DNA Damage Response R-HSA-69563
Axon guidance R-HSA-422475
ABC transporter disorders R-HSA-5619084
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Generic Transcription Pathway R-HSA-212436
Cell Cycle Checkpoints R-HSA-69620
PTEN Regulation R-HSA-6807070
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent DNA Damage Response R-HSA-69610
Asymmetric localization of PCP proteins R-HSA-4608870
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Stabilization of p53 R-HSA-69541
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'on' state R-HSA-5632684
Immune System R-HSA-168256
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of PTEN stability and activity R-HSA-8948751
RAF/MAP kinase cascade R-HSA-5673001
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of AXIN R-HSA-4641257
Metabolism of amino acids and derivatives R-HSA-71291
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vpu mediated degradation of CD4 R-HSA-180534
G1/S DNA Damage Checkpoints R-HSA-69615
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH R-HSA-157118
Signaling by the B Cell Receptor (BCR) R-HSA-983705
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mitotic cell cycle R-HSA-453276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Class I MHC mediated antigen processing & presentation R-HSA-983169
Programmed Cell Death R-HSA-5357801
Separation of Sister Chromatids R-HSA-2467813
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Nuclear events mediated by NFE2L2 R-HSA-9759194
Interleukin-1 signaling R-HSA-9020702
G2/M Checkpoints R-HSA-69481
Metabolism of proteins R-HSA-392499
Orc1 removal from chromatin R-HSA-68949
Defective CFTR causes cystic fibrosis R-HSA-5678895
HIV Infection R-HSA-162906
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Cyclin E associated events during G1/S transition R-HSA-69202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of Apoptosis R-HSA-169911
Adaptive Immune System R-HSA-1280218
Disorders of transmembrane transporters R-HSA-5619115
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by ROBO receptors R-HSA-376176
Metabolism of polyamines R-HSA-351202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Synthesis of DNA R-HSA-69239
Switching of origins to a post-replicative state R-HSA-69052
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
KEAP1-NFE2L2 pathway R-HSA-9755511
Ub-specific processing proteases R-HSA-5689880
Signaling by Interleukins R-HSA-449147
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Hedgehog ligand biogenesis R-HSA-5358346
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH4 R-HSA-9013694
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX3 R-HSA-8878159
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of RUNX3 expression and activity R-HSA-8941858
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing-Cross presentation R-HSA-1236975
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic G2-G2/M phases R-HSA-453274
ER-Phagosome pathway R-HSA-1236974
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Host Interactions of HIV factors R-HSA-162909
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
Cell Cycle R-HSA-1640170
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Cytokine Signaling in Immune system R-HSA-1280215
Vif-mediated degradation of APOBEC3G R-HSA-180585
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of RNA R-HSA-8953854
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S Transition R-HSA-69206
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
Interleukin-1 family signaling R-HSA-446652
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Anaphase R-HSA-68882
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX1 R-HSA-8878171
G2/M Checkpoints R-HSA-69481
Downstream TCR signaling R-HSA-202424
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants are degraded by ERAD R-HSA-5362768
Orc1 removal from chromatin R-HSA-68949
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Generic Transcription Pathway R-HSA-212436
S Phase R-HSA-69242
Ub-specific processing proteases R-HSA-5689880
Negative regulation of NOTCH4 signaling R-HSA-9604323
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FCERI mediated NF-kB activation R-HSA-2871837
Nuclear events mediated by NFE2L2 R-HSA-9759194
PCP/CE pathway R-HSA-4086400
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
UCH proteinases R-HSA-5689603
Cellular responses to stimuli R-HSA-8953897
Neddylation R-HSA-8951664
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Vpu mediated degradation of CD4 R-HSA-180534
Antigen processing-Cross presentation R-HSA-1236975
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of AXIN R-HSA-4641257
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RAS by GAPs R-HSA-5658442
Immune System R-HSA-168256
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signal Transduction R-HSA-162582
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of DVL R-HSA-4641258
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Intracellular signaling by second messengers R-HSA-9006925
HIV Infection R-HSA-162906
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
Disease R-HSA-1643685
Signaling by Interleukins R-HSA-449147
Metabolism of RNA R-HSA-8953854
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Synthesis of DNA R-HSA-69239
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Metaphase and Anaphase R-HSA-2555396
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCF dependent signaling in response to WNT R-HSA-201681
C-type lectin receptors (CLRs) R-HSA-5621481
ABC transporter disorders R-HSA-5619084
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH R-HSA-157118
Cyclin E associated events during G1/S transition R-HSA-69202
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Separation of Sister Chromatids R-HSA-2467813
Metabolism R-HSA-1430728
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by ROBO receptors R-HSA-376176
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Interleukin-1 signaling R-HSA-9020702
Mitotic Anaphase R-HSA-68882
ABC-family proteins mediated transport R-HSA-382556
Programmed Cell Death R-HSA-5357801
MAPK family signaling cascades R-HSA-5683057
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to chemical stress R-HSA-9711123
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by NOTCH4 R-HSA-9013694
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent DNA Damage Response R-HSA-69610
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stress R-HSA-2262752
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transport of small molecules R-HSA-382551
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Hedgehog R-HSA-5358351
Metabolism of amino acids and derivatives R-HSA-71291
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic G2-G2/M phases R-HSA-453274
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
Developmental Biology R-HSA-1266738
Regulation of RUNX2 expression and activity R-HSA-8939902
Adaptive Immune System R-HSA-1280218
Post-translational protein modification R-HSA-597592
Apoptosis R-HSA-109581
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog ligand biogenesis R-HSA-5358346
Gene expression (Transcription) R-HSA-74160
TCR signaling R-HSA-202403
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of NF-kappaB in B cells R-HSA-1169091
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 family signaling R-HSA-446652
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
HIV Infection R-HSA-162906
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of polyamines R-HSA-351202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Class I MHC mediated antigen processing & presentation R-HSA-983169
ABC-family proteins mediated transport R-HSA-382556
Metabolism R-HSA-1430728
PCP/CE pathway R-HSA-4086400
FCERI mediated NF-kB activation R-HSA-2871837
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Gene expression (Transcription) R-HSA-74160
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK6/MAPK4 signaling R-HSA-5687128
G2/M Transition R-HSA-69275
Transport of small molecules R-HSA-382551
Cell Cycle Checkpoints R-HSA-69620
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Ub-specific processing proteases R-HSA-5689880
Degradation of AXIN R-HSA-4641257
Developmental Biology R-HSA-1266738
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic G2-G2/M phases R-HSA-453274
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'on' state R-HSA-5632684
Degradation of DVL R-HSA-4641258
Cell Cycle R-HSA-1640170
Cellular responses to stimuli R-HSA-8953897
Post-translational protein modification R-HSA-597592
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
UCH proteinases R-HSA-5689603
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
Interleukin-1 signaling R-HSA-9020702
Signaling by Interleukins R-HSA-449147
Negative regulation of NOTCH4 signaling R-HSA-9604323
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
KEAP1-NFE2L2 pathway R-HSA-9755511
Neddylation R-HSA-8951664
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disorders of transmembrane transporters R-HSA-5619115
Synthesis of DNA R-HSA-69239
Regulation of PTEN stability and activity R-HSA-8948751
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Hh mutants are degraded by ERAD R-HSA-5362768
ABC transporter disorders R-HSA-5619084
Signaling by ROBO receptors R-HSA-376176
Axon guidance R-HSA-422475
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of mitotic cell cycle R-HSA-453276
TCR signaling R-HSA-202403
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Independent DNA Damage Response R-HSA-69610
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Deubiquitination R-HSA-5688426
Separation of Sister Chromatids R-HSA-2467813
M Phase R-HSA-68886
Hedgehog 'off' state R-HSA-5610787
PTEN Regulation R-HSA-6807070
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX3 R-HSA-8878159
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
RAF/MAP kinase cascade R-HSA-5673001
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of expression of SLITs and ROBOs R-HSA-9010553
C-type lectin receptors (CLRs) R-HSA-5621481
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
DNA Replication R-HSA-69306
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Anaphase R-HSA-68882
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to hypoxia R-HSA-1234174
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
Downstream TCR signaling R-HSA-202424
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX2 R-HSA-8878166
Antigen processing-Cross presentation R-HSA-1236975
Cellular response to chemical stress R-HSA-9711123
Nervous system development R-HSA-9675108
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by WNT R-HSA-195721
Regulation of RUNX3 expression and activity R-HSA-8941858
Immune System R-HSA-168256
G1/S Transition R-HSA-69206
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
MAPK family signaling cascades R-HSA-5683057
DNA Replication Pre-Initiation R-HSA-69002
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH4 R-HSA-9013694
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
Assembly of the pre-replicative complex R-HSA-68867
G2/M Checkpoints R-HSA-69481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
Beta-catenin independent WNT signaling R-HSA-3858494
Nuclear events mediated by NFE2L2 R-HSA-9759194
Programmed Cell Death R-HSA-5357801
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G1 phase and G1/S transition R-HSA-453279
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
Hedgehog 'off' state R-HSA-5610787
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Infectious disease R-HSA-5663205
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of beta-catenin by the destruction complex R-HSA-195253
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
p53-Independent DNA Damage Response R-HSA-69610
G2/M Checkpoints R-HSA-69481
Regulation of Apoptosis R-HSA-169911
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Transition R-HSA-69275
FCERI mediated NF-kB activation R-HSA-2871837
Asymmetric localization of PCP proteins R-HSA-4608870
UCH proteinases R-HSA-5689603
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Gene expression (Transcription) R-HSA-74160
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hh mutants abrogate ligand secretion R-HSA-5387390
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH R-HSA-157118
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Innate Immune System R-HSA-168249
Defective CFTR causes cystic fibrosis R-HSA-5678895
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog ligand biogenesis R-HSA-5358346
Adaptive Immune System R-HSA-1280218
Signaling by the B Cell Receptor (BCR) R-HSA-983705
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism R-HSA-1430728
PTEN Regulation R-HSA-6807070
MAPK family signaling cascades R-HSA-5683057
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of RNA R-HSA-8953854
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX3 R-HSA-8878159
Axon guidance R-HSA-422475
Assembly of the pre-replicative complex R-HSA-68867
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Apoptosis R-HSA-109581
Signaling by WNT R-HSA-195721
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of PTEN stability and activity R-HSA-8948751
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
TCF dependent signaling in response to WNT R-HSA-201681
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Class I MHC mediated antigen processing & presentation R-HSA-983169
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stress R-HSA-2262752
TCR signaling R-HSA-202403
DNA Replication R-HSA-69306
Cellular response to hypoxia R-HSA-1234174
Metabolism of proteins R-HSA-392499
HIV Infection R-HSA-162906
Signaling by Hedgehog R-HSA-5358351
Cell Cycle Checkpoints R-HSA-69620
Vif-mediated degradation of APOBEC3G R-HSA-180585
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Switching of origins to a post-replicative state R-HSA-69052
S Phase R-HSA-69242
Programmed Cell Death R-HSA-5357801
Mitotic G2-G2/M phases R-HSA-453274
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 family signaling R-HSA-446652
Degradation of AXIN R-HSA-4641257
RNA Polymerase II Transcription R-HSA-73857
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Transport of small molecules R-HSA-382551
Signaling by Interleukins R-HSA-449147
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of amino acids and derivatives R-HSA-71291
ABC transporter disorders R-HSA-5619084
PCP/CE pathway R-HSA-4086400
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Synthesis of DNA R-HSA-69239
Intracellular signaling by second messengers R-HSA-9006925
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Developmental Biology R-HSA-1266738
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of RAS by GAPs R-HSA-5658442
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
ABC-family proteins mediated transport R-HSA-382556
DNA Replication Pre-Initiation R-HSA-69002
Disease R-HSA-1643685
Separation of Sister Chromatids R-HSA-2467813
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants are degraded by ERAD R-HSA-5362768
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic Anaphase R-HSA-68882
G1/S Transition R-HSA-69206
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Nervous system development R-HSA-9675108
Cell Cycle, Mitotic R-HSA-69278
ER-Phagosome pathway R-HSA-1236974
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Immune System R-HSA-168256
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism of polyamines R-HSA-351202
PTEN Regulation R-HSA-6807070
Metabolism R-HSA-1430728
Infectious disease R-HSA-5663205
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
Signaling by ROBO receptors R-HSA-376176
Immune System R-HSA-168256
Assembly of the pre-replicative complex R-HSA-68867
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to hypoxia R-HSA-1234174
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of AXIN R-HSA-4641257
Apoptosis R-HSA-109581
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Axon guidance R-HSA-422475
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Interleukin-1 signaling R-HSA-9020702
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transcriptional regulation by RUNX2 R-HSA-8878166
Deubiquitination R-HSA-5688426
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ABC transporter disorders R-HSA-5619084
Signal Transduction R-HSA-162582
Cellular response to chemical stress R-HSA-9711123
Switching of origins to a post-replicative state R-HSA-69052
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
S Phase R-HSA-69242
Degradation of GLI2 by the proteasome R-HSA-5610783
G2/M Transition R-HSA-69275
Metabolism of RNA R-HSA-8953854
Synthesis of DNA R-HSA-69239
Hedgehog 'on' state R-HSA-5632684
DNA Replication R-HSA-69306
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Interleukins R-HSA-449147
Cellular responses to stress R-HSA-2262752
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
ABC-family proteins mediated transport R-HSA-382556
Metabolism of proteins R-HSA-392499
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CLEC7A (Dectin-1) signaling R-HSA-5607764
Orc1 removal from chromatin R-HSA-68949
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Beta-catenin independent WNT signaling R-HSA-3858494
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Transport of small molecules R-HSA-382551
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Hedgehog R-HSA-5358351
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
HIV Infection R-HSA-162906
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G1/S Transition R-HSA-69206
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle R-HSA-1640170
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog 'off' state R-HSA-5610787
ER-Phagosome pathway R-HSA-1236974
Separation of Sister Chromatids R-HSA-2467813
Mitotic G1 phase and G1/S transition R-HSA-453279
TCR signaling R-HSA-202403
G2/M Checkpoints R-HSA-69481
M Phase R-HSA-68886
Neddylation R-HSA-8951664
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hh mutants abrogate ligand secretion R-HSA-5387390
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of polyamines R-HSA-351202
Defective CFTR causes cystic fibrosis R-HSA-5678895
PCP/CE pathway R-HSA-4086400
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Adaptive Immune System R-HSA-1280218
Activation of NF-kappaB in B cells R-HSA-1169091
DNA Replication Pre-Initiation R-HSA-69002
p53-Dependent G1 DNA Damage Response R-HSA-69563
UCH proteinases R-HSA-5689603
p53-Independent DNA Damage Response R-HSA-69610
Generic Transcription Pathway R-HSA-212436
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of DVL R-HSA-4641258
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Innate Immune System R-HSA-168249
Regulation of mitotic cell cycle R-HSA-453276
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stimuli R-HSA-8953897
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by NOTCH R-HSA-157118
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Asymmetric localization of PCP proteins R-HSA-4608870
Programmed Cell Death R-HSA-5357801
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
Hedgehog ligand biogenesis R-HSA-5358346
ER-Phagosome pathway R-HSA-1236974
Signal Transduction R-HSA-162582
Signaling by NOTCH4 R-HSA-9013694
Stabilization of p53 R-HSA-69541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
Cyclin E associated events during G1/S transition R-HSA-69202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Assembly of the pre-replicative complex R-HSA-68867
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI2 by the proteasome R-HSA-5610783
C-type lectin receptors (CLRs) R-HSA-5621481
Intracellular signaling by second messengers R-HSA-9006925
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by Interleukins R-HSA-449147
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Independent DNA Damage Response R-HSA-69610
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic Metaphase and Anaphase R-HSA-2555396
FCERI mediated NF-kB activation R-HSA-2871837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism R-HSA-1430728
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of NF-kappaB in B cells R-HSA-1169091
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Synthesis of DNA R-HSA-69239
Metabolism of amino acids and derivatives R-HSA-71291
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by Hedgehog R-HSA-5358351
Gene expression (Transcription) R-HSA-74160
Regulation of mitotic cell cycle R-HSA-453276
Nuclear events mediated by NFE2L2 R-HSA-9759194
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'off' state R-HSA-5610787
Metabolism of RNA R-HSA-8953854
KEAP1-NFE2L2 pathway R-HSA-9755511
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
Cellular response to chemical stress R-HSA-9711123
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Innate Immune System R-HSA-168249
Transport of small molecules R-HSA-382551
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
PCP/CE pathway R-HSA-4086400
Regulation of expression of SLITs and ROBOs R-HSA-9010553
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cell Cycle Checkpoints R-HSA-69620
Degradation of AXIN R-HSA-4641257
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
Downstream TCR signaling R-HSA-202424
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication Pre-Initiation R-HSA-69002
Beta-catenin independent WNT signaling R-HSA-3858494
MAPK6/MAPK4 signaling R-HSA-5687128
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ABC transporter disorders R-HSA-5619084
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disorders of transmembrane transporters R-HSA-5619115
Immune System R-HSA-168256
Apoptosis R-HSA-109581
Regulation of Apoptosis R-HSA-169911
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Adaptive Immune System R-HSA-1280218
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX2 R-HSA-8878166
Orc1 removal from chromatin R-HSA-68949
Infectious disease R-HSA-5663205
ABC-family proteins mediated transport R-HSA-382556
DNA Replication R-HSA-69306
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCF dependent signaling in response to WNT R-HSA-201681
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
Interleukin-1 family signaling R-HSA-446652
G2/M Checkpoints R-HSA-69481
Cellular response to hypoxia R-HSA-1234174
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants abrogate ligand secretion R-HSA-5387390
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S Transition R-HSA-69206
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
UCH proteinases R-HSA-5689603
TCR signaling R-HSA-202403
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
Axon guidance R-HSA-422475
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by ROBO receptors R-HSA-376176
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Antigen processing-Cross presentation R-HSA-1236975
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog 'on' state R-HSA-5632684
HIV Infection R-HSA-162906
Deubiquitination R-HSA-5688426
Host Interactions of HIV factors R-HSA-162909
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
M Phase R-HSA-68886
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
Class I MHC mediated antigen processing & presentation R-HSA-983169
DNA Replication R-HSA-69306
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCF dependent signaling in response to WNT R-HSA-201681
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
S Phase R-HSA-69242
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Cyclin E associated events during G1/S transition R-HSA-69202
Intracellular signaling by second messengers R-HSA-9006925
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC-family proteins mediated transport R-HSA-382556
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Dependent G1 DNA Damage Response R-HSA-69563
Synthesis of DNA R-HSA-69239
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX3 R-HSA-8878159
Infectious disease R-HSA-5663205
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
ER-Phagosome pathway R-HSA-1236974
Immune System R-HSA-168256
Hedgehog 'on' state R-HSA-5632684
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cellular response to chemical stress R-HSA-9711123
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Neddylation R-HSA-8951664
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK family signaling cascades R-HSA-5683057
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G1 phase and G1/S transition R-HSA-453279
Deubiquitination R-HSA-5688426
Mitotic Anaphase R-HSA-68882
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Programmed Cell Death R-HSA-5357801
Hedgehog 'off' state R-HSA-5610787
Interleukin-1 family signaling R-HSA-446652
Developmental Biology R-HSA-1266738
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of proteins R-HSA-392499
Apoptosis R-HSA-109581
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants are degraded by ERAD R-HSA-5362768
Axon guidance R-HSA-422475
Disorders of transmembrane transporters R-HSA-5619115
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stress R-HSA-2262752
Disease R-HSA-1643685
Signaling by WNT R-HSA-195721
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
TCR signaling R-HSA-202403
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RAS by GAPs R-HSA-5658442
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of polyamines R-HSA-351202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to hypoxia R-HSA-1234174
G2/M Checkpoints R-HSA-69481
Ub-specific processing proteases R-HSA-5689880
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Hedgehog R-HSA-5358351
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of AXIN R-HSA-4641257
Mitotic G2-G2/M phases R-HSA-453274
Regulation of Apoptosis R-HSA-169911
p53-Independent DNA Damage Response R-HSA-69610
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism R-HSA-1430728
G1/S Transition R-HSA-69206
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle R-HSA-1640170
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
PTEN Regulation R-HSA-6807070
G2/M Transition R-HSA-69275
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
FCERI mediated NF-kB activation R-HSA-2871837
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Interleukin-1 signaling R-HSA-9020702
Antigen processing-Cross presentation R-HSA-1236975
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Orc1 removal from chromatin R-HSA-68949
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX2 expression and activity R-HSA-8939902
Post-translational protein modification R-HSA-597592
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of DVL R-HSA-4641258
Switching of origins to a post-replicative state R-HSA-69052
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH R-HSA-157118
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX1 R-HSA-8878171
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Innate Immune System R-HSA-168249
Cell Cycle Checkpoints R-HSA-69620
RAF/MAP kinase cascade R-HSA-5673001
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of PTEN stability and activity R-HSA-8948751
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000087191
NCBI gene (formerly Entrezgene) 5705
GeneCards 9552
HGNC Symbol HGNC:9552
MIM gene 601681
UniProtKB Gene Name P62195
WikiGene 5705
Gene: MMP8
Ensembl ID : ENSG00000118113
Description: matrix metallopeptidase 8
Gene Synonyms: CLG1
3 APIs:
111 Possible Orthologues:

Innate Immune System R-HSA-168249
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Neutrophil degranulation R-HSA-6798695
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Degradation of the extracellular matrix R-HSA-1474228
Activation of Matrix Metalloproteinases R-HSA-1592389
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Collagen degradation R-HSA-1442490
Immune System R-HSA-168256
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Neutrophil degranulation R-HSA-6798695
Collagen degradation R-HSA-1442490
Innate Immune System R-HSA-168249
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Neutrophil degranulation R-HSA-6798695
Collagen degradation R-HSA-1442490
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Activation of Matrix Metalloproteinases R-HSA-1592389
Collagen degradation R-HSA-1442490
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Degradation of the extracellular matrix R-HSA-1474228
Immune System R-HSA-168256
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Neutrophil degranulation R-HSA-6798695
Activation of Matrix Metalloproteinases R-HSA-1592389
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Extracellular matrix organization R-HSA-1474244
Innate Immune System R-HSA-168249
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Immune System R-HSA-168256
Activation of Matrix Metalloproteinases R-HSA-1592389
Collagen degradation R-HSA-1442490
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695

Expression Atlas ENSG00000118113
NCBI gene (formerly Entrezgene) 4317
GeneCards 7175
HGNC Symbol HGNC:7175
MIM gene 120355
UniProtKB Gene Name P22894
WikiGene 4317