Gene: MMP1
Ensembl ID : ENSG00000196611
Description: matrix metallopeptidase 1
Gene Synonyms: CLG
4 APIs:
348 Possible Orthologues:

Basigin interactions R-HSA-210991
Collagen degradation R-HSA-1442490
Cell surface interactions at the vascular wall R-HSA-202733
Metabolism of proteins R-HSA-392499
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Hemostasis R-HSA-109582
Degradation of the extracellular matrix R-HSA-1474228
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Collagen degradation R-HSA-1442490
Extracellular matrix organization R-HSA-1474244
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Activation of Matrix Metalloproteinases R-HSA-1592389
Metabolism of proteins R-HSA-392499
Cell surface interactions at the vascular wall R-HSA-202733
Immune System R-HSA-168256
Basigin interactions R-HSA-210991
Hemostasis R-HSA-109582
Degradation of the extracellular matrix R-HSA-1474228
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Cell surface interactions at the vascular wall R-HSA-202733
Collagen degradation R-HSA-1442490
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Hemostasis R-HSA-109582
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Immune System R-HSA-168256
Cytokine Signaling in Immune system R-HSA-1280215
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Metabolism of proteins R-HSA-392499
Signaling by Interleukins R-HSA-449147
Basigin interactions R-HSA-210991
Basigin interactions R-HSA-210991
Degradation of the extracellular matrix R-HSA-1474228
Activation of Matrix Metalloproteinases R-HSA-1592389
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Hemostasis R-HSA-109582
Cytokine Signaling in Immune system R-HSA-1280215
Cell surface interactions at the vascular wall R-HSA-202733
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Collagen degradation R-HSA-1442490
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Extracellular matrix organization R-HSA-1474244
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of the extracellular matrix R-HSA-1474228
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Basigin interactions R-HSA-210991
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Hemostasis R-HSA-109582
Collagen degradation R-HSA-1442490
Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cell surface interactions at the vascular wall R-HSA-202733
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Hemostasis R-HSA-109582
Extracellular matrix organization R-HSA-1474244
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Signaling by Interleukins R-HSA-449147
Basigin interactions R-HSA-210991
Collagen degradation R-HSA-1442490
Cell surface interactions at the vascular wall R-HSA-202733
Metabolism of proteins R-HSA-392499
Activation of Matrix Metalloproteinases R-HSA-1592389
Immune System R-HSA-168256
Degradation of the extracellular matrix R-HSA-1474228
Cytokine Signaling in Immune system R-HSA-1280215
Hemostasis R-HSA-109582
Basigin interactions R-HSA-210991
Signaling by Interleukins R-HSA-449147
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Metabolism of proteins R-HSA-392499
Cytokine Signaling in Immune system R-HSA-1280215
Extracellular matrix organization R-HSA-1474244
Cell surface interactions at the vascular wall R-HSA-202733
Activation of Matrix Metalloproteinases R-HSA-1592389
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Immune System R-HSA-168256
Collagen degradation R-HSA-1442490
Degradation of the extracellular matrix R-HSA-1474228
Immune System R-HSA-168256
Cell surface interactions at the vascular wall R-HSA-202733
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Extracellular matrix organization R-HSA-1474244
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Basigin interactions R-HSA-210991
Activation of Matrix Metalloproteinases R-HSA-1592389
Signaling by Interleukins R-HSA-449147
Collagen degradation R-HSA-1442490
Hemostasis R-HSA-109582
Metabolism of proteins R-HSA-392499
Degradation of the extracellular matrix R-HSA-1474228
Cell surface interactions at the vascular wall R-HSA-202733
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Collagen degradation R-HSA-1442490
Signaling by Interleukins R-HSA-449147
Degradation of the extracellular matrix R-HSA-1474228
Basigin interactions R-HSA-210991
Metabolism of proteins R-HSA-392499
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Hemostasis R-HSA-109582
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Immune System R-HSA-168256
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of the extracellular matrix R-HSA-1474228
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cytokine Signaling in Immune system R-HSA-1280215
Extracellular matrix organization R-HSA-1474244
Hemostasis R-HSA-109582
Basigin interactions R-HSA-210991
Immune System R-HSA-168256
Collagen degradation R-HSA-1442490
Metabolism of proteins R-HSA-392499
Activation of Matrix Metalloproteinases R-HSA-1592389
Signaling by Interleukins R-HSA-449147
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Cell surface interactions at the vascular wall R-HSA-202733

Expression Atlas ENSG00000196611
NCBI gene (formerly Entrezgene) 4312
GeneCards 7155
HGNC Symbol HGNC:7155
MIM gene 120353
MIM morbid 606963
UniProtKB Gene Name P03956
WikiGene 4312
Gene: ECE1
Ensembl ID : ENSG00000117298
Description: endothelin converting enzyme 1
Gene Synonyms: ECE
1 APIs:
230 Possible Orthologues:

Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076

Expression Atlas ENSG00000117298
NCBI gene (formerly Entrezgene) 1889
GeneCards 3146
HGNC Symbol HGNC:3146
MIM gene 600423
MIM morbid 613870
UniProtKB Gene Name P42892
WikiGene 1889
Gene: REN
Ensembl ID : ENSG00000143839
Description: renin
Gene Synonyms:
2 APIs:
220 Possible Orthologues:

Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736

Expression Atlas ENSG00000143839
NCBI gene (formerly Entrezgene) 5972
GeneCards 9958
HGNC Symbol HGNC:9958
MIM gene 179820
MIM morbid 613092
UniProtKB Gene Name P00797
WikiGene 5972
Gene: CASP1
Ensembl ID : ENSG00000137752
Description: caspase 1
Gene Synonyms: ICE,IL1BC
2 APIs:
427 Possible Orthologues:

RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
The AIM2 inflammasome R-HSA-844615
Purinergic signaling in leishmaniasis infection R-HSA-9660826
NOD1/2 Signaling Pathway R-HSA-168638
Cytokine Signaling in Immune system R-HSA-1280215
Gene expression (Transcription) R-HSA-74160
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
The IPAF inflammasome R-HSA-844623
Pyroptosis R-HSA-5620971
Infectious disease R-HSA-5663205
Interleukin-1 processing R-HSA-448706
Signaling by Interleukins R-HSA-449147
The NLRP3 inflammasome R-HSA-844456
Inflammasomes R-HSA-622312
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV Infections R-HSA-9679506
Leishmania infection R-HSA-9658195
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Regulated Necrosis R-HSA-5218859
Programmed Cell Death R-HSA-5357801
Interleukin-37 signaling R-HSA-9008059
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-1-host interactions R-HSA-9692914
Interleukin-1 family signaling R-HSA-446652
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
Infectious disease R-HSA-5663205
The AIM2 inflammasome R-HSA-844615
Regulated Necrosis R-HSA-5218859
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Cytokine Signaling in Immune system R-HSA-1280215
Leishmania infection R-HSA-9658195
Pyroptosis R-HSA-5620971
Programmed Cell Death R-HSA-5357801
Generic Transcription Pathway R-HSA-212436
Cell recruitment (pro-inflammatory response) R-HSA-9664424
The NLRP3 inflammasome R-HSA-844456
Gene expression (Transcription) R-HSA-74160
Inflammasomes R-HSA-622312
Innate Immune System R-HSA-168249
Interleukin-1 processing R-HSA-448706
SARS-CoV-1-host interactions R-HSA-9692914
Interleukin-37 signaling R-HSA-9008059
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
The IPAF inflammasome R-HSA-844623
Disease R-HSA-1643685
Signaling by Interleukins R-HSA-449147
Interleukin-1 family signaling R-HSA-446652
SARS-CoV-1 Infection R-HSA-9678108
NOD1/2 Signaling Pathway R-HSA-168638
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV Infections R-HSA-9679506
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Immune System R-HSA-168256
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Infectious disease R-HSA-5663205
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Generic Transcription Pathway R-HSA-212436
The NLRP3 inflammasome R-HSA-844456
Cytokine Signaling in Immune system R-HSA-1280215
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV Infections R-HSA-9679506
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Innate Immune System R-HSA-168249
The IPAF inflammasome R-HSA-844623
NOD1/2 Signaling Pathway R-HSA-168638
Interleukin-37 signaling R-HSA-9008059
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Regulated Necrosis R-HSA-5218859
SARS-CoV-1-host interactions R-HSA-9692914
Leishmania infection R-HSA-9658195
SARS-CoV-1 Infection R-HSA-9678108
Inflammasomes R-HSA-622312
Disease R-HSA-1643685
The AIM2 inflammasome R-HSA-844615
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Transcriptional Regulation by TP53 R-HSA-3700989
Pyroptosis R-HSA-5620971
Interleukin-1 processing R-HSA-448706
RNA Polymerase II Transcription R-HSA-73857
Cytokine Signaling in Immune system R-HSA-1280215
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
Signaling by Interleukins R-HSA-449147
Inflammasomes R-HSA-622312
Pyroptosis R-HSA-5620971
Disease R-HSA-1643685
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Gene expression (Transcription) R-HSA-74160
SARS-CoV Infections R-HSA-9679506
SARS-CoV-1-host interactions R-HSA-9692914
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Cell recruitment (pro-inflammatory response) R-HSA-9664424
The NLRP3 inflammasome R-HSA-844456
Regulated Necrosis R-HSA-5218859
Immune System R-HSA-168256
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Programmed Cell Death R-HSA-5357801
The IPAF inflammasome R-HSA-844623
Innate Immune System R-HSA-168249
Leishmania infection R-HSA-9658195
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 processing R-HSA-448706
The AIM2 inflammasome R-HSA-844615
NOD1/2 Signaling Pathway R-HSA-168638
Interleukin-37 signaling R-HSA-9008059
SARS-CoV-1 Infection R-HSA-9678108
Transcriptional Regulation by TP53 R-HSA-3700989
The NLRP3 inflammasome R-HSA-844456
The IPAF inflammasome R-HSA-844623
NOD1/2 Signaling Pathway R-HSA-168638
Interleukin-1 processing R-HSA-448706
RNA Polymerase II Transcription R-HSA-73857
Leishmania infection R-HSA-9658195
Regulated Necrosis R-HSA-5218859
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Immune System R-HSA-168256
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Cytokine Signaling in Immune system R-HSA-1280215
The AIM2 inflammasome R-HSA-844615
Inflammasomes R-HSA-622312
Generic Transcription Pathway R-HSA-212436
Signaling by Interleukins R-HSA-449147
Pyroptosis R-HSA-5620971
Innate Immune System R-HSA-168249
SARS-CoV-1 Infection R-HSA-9678108
Gene expression (Transcription) R-HSA-74160
SARS-CoV-1-host interactions R-HSA-9692914
Infectious disease R-HSA-5663205
Interleukin-37 signaling R-HSA-9008059
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Transcriptional Regulation by TP53 R-HSA-3700989
Interleukin-1 family signaling R-HSA-446652
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Programmed Cell Death R-HSA-5357801
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Leishmania infection R-HSA-9658195
Pyroptosis R-HSA-5620971
SARS-CoV-1 Infection R-HSA-9678108
Inflammasomes R-HSA-622312
Disease R-HSA-1643685
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV Infections R-HSA-9679506
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Cytokine Signaling in Immune system R-HSA-1280215
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Generic Transcription Pathway R-HSA-212436
Regulated Necrosis R-HSA-5218859
Innate Immune System R-HSA-168249
The NLRP3 inflammasome R-HSA-844456
SARS-CoV-1-host interactions R-HSA-9692914
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Interleukin-1 processing R-HSA-448706
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Interleukin-37 signaling R-HSA-9008059
The IPAF inflammasome R-HSA-844623
Transcriptional Regulation by TP53 R-HSA-3700989
Programmed Cell Death R-HSA-5357801
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
NOD1/2 Signaling Pathway R-HSA-168638
Infectious disease R-HSA-5663205
Interleukin-1 family signaling R-HSA-446652
The AIM2 inflammasome R-HSA-844615
Cell recruitment (pro-inflammatory response) R-HSA-9664424

Expression Atlas ENSG00000137752
NCBI gene (formerly Entrezgene) 834
GeneCards 1499
HGNC Symbol HGNC:1499
MIM gene 147678
UniProtKB Gene Name Q5FBZ0
WikiGene 834
Gene: PSMB2
Ensembl ID : ENSG00000126067
Description: proteasome 20S subunit beta 2
Gene Synonyms: HC7-I
6 APIs:
218 Possible Orthologues:

G1/S Transition R-HSA-69206
Signaling by NOTCH R-HSA-157118
PIP3 activates AKT signaling R-HSA-1257604
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog 'off' state R-HSA-5610787
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of PTEN stability and activity R-HSA-8948751
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PCP/CE pathway R-HSA-4086400
Neddylation R-HSA-8951664
Transport of small molecules R-HSA-382551
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle Checkpoints R-HSA-69620
HIV Infection R-HSA-162906
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of RNA R-HSA-8953854
MAPK1/MAPK3 signaling R-HSA-5684996
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signal Transduction R-HSA-162582
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by NOTCH R-HSA-157118
Degradation of GLI2 by the proteasome R-HSA-5610783
Separation of Sister Chromatids R-HSA-2467813
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Apoptosis R-HSA-109581
Activation of NF-kappaB in B cells R-HSA-1169091
DNA Replication R-HSA-69306
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Host Interactions of HIV factors R-HSA-162909
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
Innate Immune System R-HSA-168249
Antigen processing-Cross presentation R-HSA-1236975
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of proteins R-HSA-392499
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX1 R-HSA-8878171
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
Downstream TCR signaling R-HSA-202424
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RAF/MAP kinase cascade R-HSA-5673001
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
Assembly of the pre-replicative complex R-HSA-68867
Signaling by Interleukins R-HSA-449147
Metabolism of polyamines R-HSA-351202
Metabolism R-HSA-1430728
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK family signaling cascades R-HSA-5683057
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by WNT R-HSA-195721
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PTEN Regulation R-HSA-6807070
FCERI mediated NF-kB activation R-HSA-2871837
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
CLEC7A (Dectin-1) signaling R-HSA-5607764
UCH proteinases R-HSA-5689603
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of RAS by GAPs R-HSA-5658442
TCR signaling R-HSA-202403
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G2-G2/M phases R-HSA-453274
ABC transporter disorders R-HSA-5619084
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Orc1 removal from chromatin R-HSA-68949
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular response to chemical stress R-HSA-9711123
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RUNX2 expression and activity R-HSA-8939902
Immune System R-HSA-168256
M Phase R-HSA-68886
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G2/M Checkpoints R-HSA-69481
Adaptive Immune System R-HSA-1280218
Gene expression (Transcription) R-HSA-74160
Disorders of transmembrane transporters R-HSA-5619115
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cyclin E associated events during G1/S transition R-HSA-69202
Synthesis of DNA R-HSA-69239
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of AXIN R-HSA-4641257
Mitotic Metaphase and Anaphase R-HSA-2555396
Beta-catenin independent WNT signaling R-HSA-3858494
Disease R-HSA-1643685
Stabilization of p53 R-HSA-69541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle, Mitotic R-HSA-69278
Mitotic G1 phase and G1/S transition R-HSA-453279
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'on' state R-HSA-5632684
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Hedgehog R-HSA-5358351
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 signaling R-HSA-9020702
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of beta-catenin by the destruction complex R-HSA-195253
Negative regulation of NOTCH4 signaling R-HSA-9604323
Interleukin-1 family signaling R-HSA-446652
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Deubiquitination R-HSA-5688426
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent DNA Damage Response R-HSA-69610
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
Infectious disease R-HSA-5663205
DNA Replication Pre-Initiation R-HSA-69002
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle R-HSA-1640170
G1/S DNA Damage Checkpoints R-HSA-69615
Programmed Cell Death R-HSA-5357801
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of Apoptosis R-HSA-169911
Developmental Biology R-HSA-1266738
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
G1/S Transition R-HSA-69206
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic Anaphase R-HSA-68882
Infectious disease R-HSA-5663205
Cell Cycle Checkpoints R-HSA-69620
Neddylation R-HSA-8951664
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 family signaling R-HSA-446652
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of proteins R-HSA-392499
Apoptosis R-HSA-109581
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
Antigen processing-Cross presentation R-HSA-1236975
UCH proteinases R-HSA-5689603
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disease R-HSA-1643685
p53-Independent DNA Damage Response R-HSA-69610
Regulation of expression of SLITs and ROBOs R-HSA-9010553
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RAS by GAPs R-HSA-5658442
Signaling by WNT R-HSA-195721
Hh mutants abrogate ligand secretion R-HSA-5387390
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cytokine Signaling in Immune system R-HSA-1280215
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Innate Immune System R-HSA-168249
Intracellular signaling by second messengers R-HSA-9006925
DNA Replication R-HSA-69306
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH4 R-HSA-9013694
Regulation of mitotic cell cycle R-HSA-453276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Deubiquitination R-HSA-5688426
MAPK6/MAPK4 signaling R-HSA-5687128
Cell Cycle, Mitotic R-HSA-69278
Separation of Sister Chromatids R-HSA-2467813
Disorders of transmembrane transporters R-HSA-5619115
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of GLI1 by the proteasome R-HSA-5610780
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism of RNA R-HSA-8953854
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Beta-catenin independent WNT signaling R-HSA-3858494
Programmed Cell Death R-HSA-5357801
ABC-family proteins mediated transport R-HSA-382556
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ub-specific processing proteases R-HSA-5689880
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Developmental Biology R-HSA-1266738
Metabolism of polyamines R-HSA-351202
ER-Phagosome pathway R-HSA-1236974
Cellular response to chemical stress R-HSA-9711123
Activation of NF-kappaB in B cells R-HSA-1169091
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Interleukins R-HSA-449147
DNA Replication Pre-Initiation R-HSA-69002
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle R-HSA-1640170
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PCP/CE pathway R-HSA-4086400
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
Signal Transduction R-HSA-162582
Metabolism of amino acids and derivatives R-HSA-71291
Gene expression (Transcription) R-HSA-74160
Hedgehog 'on' state R-HSA-5632684
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular responses to stimuli R-HSA-8953897
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transport of small molecules R-HSA-382551
TCR signaling R-HSA-202403
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX3 expression and activity R-HSA-8941858
RAF/MAP kinase cascade R-HSA-5673001
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism R-HSA-1430728
Host Interactions of HIV factors R-HSA-162909
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Immune System R-HSA-168256
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Axon guidance R-HSA-422475
G1/S DNA Damage Checkpoints R-HSA-69615
Post-translational protein modification R-HSA-597592
HIV Infection R-HSA-162906
Cyclin E associated events during G1/S transition R-HSA-69202
S Phase R-HSA-69242
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Checkpoints R-HSA-69481
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of Apoptosis R-HSA-169911
Cellular responses to stress R-HSA-2262752
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
C-type lectin receptors (CLRs) R-HSA-5621481
PTEN Regulation R-HSA-6807070
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of AXIN R-HSA-4641257
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
CLEC7A (Dectin-1) signaling R-HSA-5607764
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Nervous system development R-HSA-9675108
G1/S Transition R-HSA-69206
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Synthesis of DNA R-HSA-69239
Class I MHC mediated antigen processing & presentation R-HSA-983169
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Generic Transcription Pathway R-HSA-212436
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of DVL R-HSA-4641258
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX2 R-HSA-8878166
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
Activation of NF-kappaB in B cells R-HSA-1169091
Synthesis of DNA R-HSA-69239
Regulation of Apoptosis R-HSA-169911
Hedgehog 'off' state R-HSA-5610787
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
Regulation of RAS by GAPs R-HSA-5658442
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 family signaling R-HSA-446652
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Interleukins R-HSA-449147
Nuclear events mediated by NFE2L2 R-HSA-9759194
Intracellular signaling by second messengers R-HSA-9006925
Vpu mediated degradation of CD4 R-HSA-180534
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ABC-family proteins mediated transport R-HSA-382556
G2/M Checkpoints R-HSA-69481
Transport of small molecules R-HSA-382551
Host Interactions of HIV factors R-HSA-162909
Cellular response to chemical stress R-HSA-9711123
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX2 R-HSA-8878166
Disorders of transmembrane transporters R-HSA-5619115
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of DVL R-HSA-4641258
Immune System R-HSA-168256
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by NOTCH R-HSA-157118
TCR signaling R-HSA-202403
Neddylation R-HSA-8951664
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Programmed Cell Death R-HSA-5357801
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Beta-catenin independent WNT signaling R-HSA-3858494
Cell Cycle, Mitotic R-HSA-69278
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX1 R-HSA-8878171
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
HIV Infection R-HSA-162906
RAF/MAP kinase cascade R-HSA-5673001
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
DNA Replication R-HSA-69306
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Separation of Sister Chromatids R-HSA-2467813
DNA Replication Pre-Initiation R-HSA-69002
Antigen processing-Cross presentation R-HSA-1236975
MAPK family signaling cascades R-HSA-5683057
Metabolism of polyamines R-HSA-351202
Defective CFTR causes cystic fibrosis R-HSA-5678895
KEAP1-NFE2L2 pathway R-HSA-9755511
ER-Phagosome pathway R-HSA-1236974
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by WNT R-HSA-195721
Gene expression (Transcription) R-HSA-74160
Class I MHC mediated antigen processing & presentation R-HSA-983169
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PIP3 activates AKT signaling R-HSA-1257604
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to hypoxia R-HSA-1234174
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Hedgehog R-HSA-5358351
Metabolism of RNA R-HSA-8953854
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of GLI2 by the proteasome R-HSA-5610783
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ub-specific processing proteases R-HSA-5689880
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of amino acids and derivatives R-HSA-71291
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Switching of origins to a post-replicative state R-HSA-69052
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by ROBO receptors R-HSA-376176
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of AXIN R-HSA-4641257
Innate Immune System R-HSA-168249
Downstream TCR signaling R-HSA-202424
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signal Transduction R-HSA-162582
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Anaphase R-HSA-68882
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
p53-Independent DNA Damage Response R-HSA-69610
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism R-HSA-1430728
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog 'on' state R-HSA-5632684
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Transition R-HSA-69275
Cytokine Signaling in Immune system R-HSA-1280215
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH4 R-HSA-9013694
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cell Cycle Checkpoints R-HSA-69620
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Metaphase and Anaphase R-HSA-2555396
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of GLI1 by the proteasome R-HSA-5610780
C-type lectin receptors (CLRs) R-HSA-5621481
Synthesis of DNA R-HSA-69239
Cellular response to hypoxia R-HSA-1234174
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular responses to stress R-HSA-2262752
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK family signaling cascades R-HSA-5683057
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI2 by the proteasome R-HSA-5610783
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
PCP/CE pathway R-HSA-4086400
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cyclin E associated events during G1/S transition R-HSA-69202
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Signal Transduction R-HSA-162582
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Interleukin-1 family signaling R-HSA-446652
Degradation of GLI1 by the proteasome R-HSA-5610780
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stimuli R-HSA-8953897
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
KEAP1-NFE2L2 pathway R-HSA-9755511
Ub-specific processing proteases R-HSA-5689880
p53-Independent DNA Damage Response R-HSA-69610
Disease R-HSA-1643685
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Downstream TCR signaling R-HSA-202424
ER-Phagosome pathway R-HSA-1236974
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Infectious disease R-HSA-5663205
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by ROBO receptors R-HSA-376176
ABC transporter disorders R-HSA-5619084
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transcriptional regulation by RUNX3 R-HSA-8878159
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Axon guidance R-HSA-422475
Beta-catenin independent WNT signaling R-HSA-3858494
Hh mutants are degraded by ERAD R-HSA-5362768
PTEN Regulation R-HSA-6807070
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle, Mitotic R-HSA-69278
FCERI mediated NF-kB activation R-HSA-2871837
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Stabilization of p53 R-HSA-69541
Programmed Cell Death R-HSA-5357801
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Antigen processing-Cross presentation R-HSA-1236975
C-type lectin receptors (CLRs) R-HSA-5621481
Negative regulation of NOTCH4 signaling R-HSA-9604323
Mitotic Metaphase and Anaphase R-HSA-2555396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Nervous system development R-HSA-9675108
Switching of origins to a post-replicative state R-HSA-69052
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Regulation of RAS by GAPs R-HSA-5658442
G1/S Transition R-HSA-69206
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Interleukin-1 signaling R-HSA-9020702
Degradation of DVL R-HSA-4641258
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of polyamines R-HSA-351202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Generic Transcription Pathway R-HSA-212436
Mitotic Anaphase R-HSA-68882
G2/M Transition R-HSA-69275
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cell Cycle R-HSA-1640170
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Apoptosis R-HSA-109581
Regulation of mitotic cell cycle R-HSA-453276
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX1 R-HSA-8878171
HIV Infection R-HSA-162906
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
TCF dependent signaling in response to WNT R-HSA-201681
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G1/S DNA Damage Checkpoints R-HSA-69615
Disorders of transmembrane transporters R-HSA-5619115
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
Signaling by Hedgehog R-HSA-5358351
Metabolism of proteins R-HSA-392499
Mitotic G1 phase and G1/S transition R-HSA-453279
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Neddylation R-HSA-8951664
RAF/MAP kinase cascade R-HSA-5673001
RNA Polymerase II Transcription R-HSA-73857
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of amino acids and derivatives R-HSA-71291
DNA Replication Pre-Initiation R-HSA-69002
G2/M Checkpoints R-HSA-69481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK1/MAPK3 signaling R-HSA-5684996
Class I MHC mediated antigen processing & presentation R-HSA-983169
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of Apoptosis R-HSA-169911
M Phase R-HSA-68886
Signaling by WNT R-HSA-195721
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by Interleukins R-HSA-449147
Hedgehog 'off' state R-HSA-5610787
Metabolism of RNA R-HSA-8953854
Immune System R-HSA-168256
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transport of small molecules R-HSA-382551
Host Interactions of HIV factors R-HSA-162909
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX1 R-HSA-8878171
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Axon guidance R-HSA-422475
Degradation of GLI2 by the proteasome R-HSA-5610783
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Apoptosis R-HSA-109581
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ABC-family proteins mediated transport R-HSA-382556
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK1/MAPK3 signaling R-HSA-5684996
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX3 R-HSA-8878159
Immune System R-HSA-168256
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Separation of Sister Chromatids R-HSA-2467813
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism R-HSA-1430728
Stabilization of p53 R-HSA-69541
Deubiquitination R-HSA-5688426
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of Apoptosis R-HSA-169911
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
CLEC7A (Dectin-1) signaling R-HSA-5607764
Ub-specific processing proteases R-HSA-5689880
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ER-Phagosome pathway R-HSA-1236974
Synthesis of DNA R-HSA-69239
PCP/CE pathway R-HSA-4086400
Cell Cycle, Mitotic R-HSA-69278
Cellular response to hypoxia R-HSA-1234174
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
C-type lectin receptors (CLRs) R-HSA-5621481
Signal Transduction R-HSA-162582
HIV Infection R-HSA-162906
G2/M Checkpoints R-HSA-69481
Regulation of RUNX2 expression and activity R-HSA-8939902
Host Interactions of HIV factors R-HSA-162909
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Activation of NF-kappaB in B cells R-HSA-1169091
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nervous system development R-HSA-9675108
Metabolism of polyamines R-HSA-351202
Disorders of transmembrane transporters R-HSA-5619115
Signaling by WNT R-HSA-195721
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Disease R-HSA-1643685
Degradation of beta-catenin by the destruction complex R-HSA-195253
Assembly of the pre-replicative complex R-HSA-68867
Cyclin E associated events during G1/S transition R-HSA-69202
Interleukin-1 signaling R-HSA-9020702
Downstream TCR signaling R-HSA-202424
Infectious disease R-HSA-5663205
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of RNA R-HSA-8953854
Generic Transcription Pathway R-HSA-212436
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog 'on' state R-HSA-5632684
Programmed Cell Death R-HSA-5357801
Cellular responses to stress R-HSA-2262752
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cytokine Signaling in Immune system R-HSA-1280215
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Gene expression (Transcription) R-HSA-74160
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Anaphase R-HSA-68882
TCR signaling R-HSA-202403
MAPK family signaling cascades R-HSA-5683057
KEAP1-NFE2L2 pathway R-HSA-9755511
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
Transport of small molecules R-HSA-382551
Defective CFTR causes cystic fibrosis R-HSA-5678895
G1/S Transition R-HSA-69206
Hh mutants are degraded by ERAD R-HSA-5362768
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
DNA Replication R-HSA-69306
p53-Dependent G1 DNA Damage Response R-HSA-69563
Vpu mediated degradation of CD4 R-HSA-180534
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Metaphase and Anaphase R-HSA-2555396
Switching of origins to a post-replicative state R-HSA-69052
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Post-translational protein modification R-HSA-597592
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing-Cross presentation R-HSA-1236975
Developmental Biology R-HSA-1266738
Neddylation R-HSA-8951664
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
DNA Replication Pre-Initiation R-HSA-69002
ABC transporter disorders R-HSA-5619084
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle R-HSA-1640170
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI1 by the proteasome R-HSA-5610780
PIP3 activates AKT signaling R-HSA-1257604
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
S Phase R-HSA-69242
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G2/M Transition R-HSA-69275
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by ROBO receptors R-HSA-376176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stimuli R-HSA-8953897
Metabolism of proteins R-HSA-392499
Cellular response to chemical stress R-HSA-9711123
MAPK1/MAPK3 signaling R-HSA-5684996
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle, Mitotic R-HSA-69278
Intracellular signaling by second messengers R-HSA-9006925
G1/S Transition R-HSA-69206
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nervous system development R-HSA-9675108
Infectious disease R-HSA-5663205
Cell Cycle R-HSA-1640170
PCP/CE pathway R-HSA-4086400
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of PTEN stability and activity R-HSA-8948751
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog ligand biogenesis R-HSA-5358346
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle Checkpoints R-HSA-69620
Signaling by Hedgehog R-HSA-5358351
Apoptosis R-HSA-109581
DNA Replication Pre-Initiation R-HSA-69002
Metabolism R-HSA-1430728
Disorders of transmembrane transporters R-HSA-5619115
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
Metabolism of polyamines R-HSA-351202
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Independent DNA Damage Response R-HSA-69610
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Anaphase R-HSA-68882
Activation of NF-kappaB in B cells R-HSA-1169091
Separation of Sister Chromatids R-HSA-2467813
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FCERI mediated NF-kB activation R-HSA-2871837
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by WNT R-HSA-195721
Regulation of RUNX3 expression and activity R-HSA-8941858
Cytokine Signaling in Immune system R-HSA-1280215
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
UCH proteinases R-HSA-5689603
Synthesis of DNA R-HSA-69239
Deubiquitination R-HSA-5688426
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stress R-HSA-2262752
TCR signaling R-HSA-202403
HIV Infection R-HSA-162906
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
TCF dependent signaling in response to WNT R-HSA-201681
Neddylation R-HSA-8951664
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vpu mediated degradation of CD4 R-HSA-180534
Disease R-HSA-1643685
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 signaling R-HSA-9020702
Signaling by NOTCH4 R-HSA-9013694
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cyclin E associated events during G1/S transition R-HSA-69202
Defective CFTR causes cystic fibrosis R-HSA-5678895
M Phase R-HSA-68886
Metabolism of proteins R-HSA-392499
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX2 R-HSA-8878166
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog 'on' state R-HSA-5632684
Gene expression (Transcription) R-HSA-74160
Degradation of DVL R-HSA-4641258
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Asymmetric localization of PCP proteins R-HSA-4608870
Stabilization of p53 R-HSA-69541
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of amino acids and derivatives R-HSA-71291
ABC transporter disorders R-HSA-5619084
ABC-family proteins mediated transport R-HSA-382556
Adaptive Immune System R-HSA-1280218
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI2 by the proteasome R-HSA-5610783
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of RNA R-HSA-8953854
Mitotic G2-G2/M phases R-HSA-453274
Signaling by ROBO receptors R-HSA-376176
Regulation of RAS by GAPs R-HSA-5658442
Antigen processing-Cross presentation R-HSA-1236975
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Innate Immune System R-HSA-168249
Hedgehog 'off' state R-HSA-5610787
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ER-Phagosome pathway R-HSA-1236974
Signaling by Interleukins R-HSA-449147
RAF/MAP kinase cascade R-HSA-5673001
Class I MHC mediated antigen processing & presentation R-HSA-983169
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX3 R-HSA-8878159
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1 DNA Damage Response R-HSA-69563
G2/M Checkpoints R-HSA-69481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hh mutants are degraded by ERAD R-HSA-5362768
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of Apoptosis R-HSA-169911
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PIP3 activates AKT signaling R-HSA-1257604
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to chemical stress R-HSA-9711123
Post-translational protein modification R-HSA-597592
Signaling by NOTCH R-HSA-157118
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 family signaling R-HSA-446652
S Phase R-HSA-69242
Developmental Biology R-HSA-1266738
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Assembly of the pre-replicative complex R-HSA-68867
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
Transport of small molecules R-HSA-382551
Intracellular signaling by second messengers R-HSA-9006925
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
Infectious disease R-HSA-5663205
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Assembly of the pre-replicative complex R-HSA-68867
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
ABC-family proteins mediated transport R-HSA-382556
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by Interleukins R-HSA-449147
Signaling by WNT R-HSA-195721
Downstream TCR signaling R-HSA-202424
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Post-translational protein modification R-HSA-597592
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stimuli R-HSA-8953897
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
Interleukin-1 signaling R-HSA-9020702
Regulation of PTEN stability and activity R-HSA-8948751
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
CLEC7A (Dectin-1) signaling R-HSA-5607764
Host Interactions of HIV factors R-HSA-162909
S Phase R-HSA-69242
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RAS by GAPs R-HSA-5658442
Innate Immune System R-HSA-168249
PTEN Regulation R-HSA-6807070
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
Orc1 removal from chromatin R-HSA-68949
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by ROBO receptors R-HSA-376176
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX3 R-HSA-8878159
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent DNA Damage Response R-HSA-69610
Nervous system development R-HSA-9675108
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog 'off' state R-HSA-5610787
DNA Replication R-HSA-69306
UCH proteinases R-HSA-5689603
Separation of Sister Chromatids R-HSA-2467813
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic G2-G2/M phases R-HSA-453274
FCERI mediated NF-kB activation R-HSA-2871837
Cyclin E associated events during G1/S transition R-HSA-69202
Programmed Cell Death R-HSA-5357801
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Anaphase R-HSA-68882
Hh mutants abrogate ligand secretion R-HSA-5387390
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of RNA R-HSA-8953854
Regulation of Apoptosis R-HSA-169911
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PIP3 activates AKT signaling R-HSA-1257604
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle R-HSA-1640170
Cellular response to hypoxia R-HSA-1234174
Regulation of RUNX3 expression and activity R-HSA-8941858
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RUNX2 expression and activity R-HSA-8939902
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
Regulation of mitotic cell cycle R-HSA-453276
Synthesis of DNA R-HSA-69239
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of polyamines R-HSA-351202
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Deubiquitination R-HSA-5688426
ER-Phagosome pathway R-HSA-1236974
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Hedgehog 'on' state R-HSA-5632684
Ub-specific processing proteases R-HSA-5689880
Cellular responses to stress R-HSA-2262752
Disorders of transmembrane transporters R-HSA-5619115
Cell Cycle Checkpoints R-HSA-69620
G2/M Checkpoints R-HSA-69481
DNA Replication Pre-Initiation R-HSA-69002
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of proteins R-HSA-392499
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of AXIN R-HSA-4641257
Mitotic Metaphase and Anaphase R-HSA-2555396
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of DVL R-HSA-4641258
PCP/CE pathway R-HSA-4086400
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Transition R-HSA-69275
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism R-HSA-1430728
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
HIV Infection R-HSA-162906
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cell Cycle, Mitotic R-HSA-69278
Neddylation R-HSA-8951664
Generic Transcription Pathway R-HSA-212436
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional regulation by RUNX1 R-HSA-8878171
Apoptosis R-HSA-109581
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Hedgehog R-HSA-5358351
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Defective CFTR causes cystic fibrosis R-HSA-5678895
TCR signaling R-HSA-202403
Antigen processing-Cross presentation R-HSA-1236975
Adaptive Immune System R-HSA-1280218
Mitotic G1 phase and G1/S transition R-HSA-453279
Switching of origins to a post-replicative state R-HSA-69052
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
HIV Infection R-HSA-162906
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stress R-HSA-2262752
Separation of Sister Chromatids R-HSA-2467813
Metabolism of RNA R-HSA-8953854
PIP3 activates AKT signaling R-HSA-1257604
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
FCERI mediated NF-kB activation R-HSA-2871837
Innate Immune System R-HSA-168249
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cytokine Signaling in Immune system R-HSA-1280215
Axon guidance R-HSA-422475
DNA Replication R-HSA-69306
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by ROBO receptors R-HSA-376176
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Host Interactions of HIV factors R-HSA-162909
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Vpu mediated degradation of CD4 R-HSA-180534
Infectious disease R-HSA-5663205
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by WNT R-HSA-195721
Transport of small molecules R-HSA-382551
Signaling by Interleukins R-HSA-449147
Hh mutants abrogate ligand secretion R-HSA-5387390
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
Regulation of mitotic cell cycle R-HSA-453276
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cyclin E associated events during G1/S transition R-HSA-69202
ABC-family proteins mediated transport R-HSA-382556
Disease R-HSA-1643685
Apoptosis R-HSA-109581
Metabolism of polyamines R-HSA-351202
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of DVL R-HSA-4641258
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Programmed Cell Death R-HSA-5357801
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH4 R-HSA-9013694
Interleukin-1 family signaling R-HSA-446652
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Metabolism R-HSA-1430728
M Phase R-HSA-68886
S Phase R-HSA-69242
Beta-catenin independent WNT signaling R-HSA-3858494
Antigen processing-Cross presentation R-HSA-1236975
Cellular response to chemical stress R-HSA-9711123
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
Neddylation R-HSA-8951664
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle R-HSA-1640170
Regulation of PTEN stability and activity R-HSA-8948751
Nervous system development R-HSA-9675108
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transcriptional regulation by RUNX2 R-HSA-8878166
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
C-type lectin receptors (CLRs) R-HSA-5621481
Immune System R-HSA-168256
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of AXIN R-HSA-4641257
Signaling by Hedgehog R-HSA-5358351
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
Adaptive Immune System R-HSA-1280218
G2/M Transition R-HSA-69275
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of amino acids and derivatives R-HSA-71291
TCR signaling R-HSA-202403
G1/S Transition R-HSA-69206
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
DNA Replication Pre-Initiation R-HSA-69002
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Negative regulation of NOTCH4 signaling R-HSA-9604323
ER-Phagosome pathway R-HSA-1236974
ABC transporter disorders R-HSA-5619084
Hedgehog 'off' state R-HSA-5610787
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PCP/CE pathway R-HSA-4086400
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX1 R-HSA-8878171
TCF dependent signaling in response to WNT R-HSA-201681
PTEN Regulation R-HSA-6807070
G2/M Checkpoints R-HSA-69481
Activation of NF-kappaB in B cells R-HSA-1169091
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of Apoptosis R-HSA-169911
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI1 by the proteasome R-HSA-5610780
CLEC7A (Dectin-1) signaling R-HSA-5607764
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic G1 phase and G1/S transition R-HSA-453279
Assembly of the pre-replicative complex R-HSA-68867
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RAS by GAPs R-HSA-5658442
Hh mutants are degraded by ERAD R-HSA-5362768
Disorders of transmembrane transporters R-HSA-5619115
Developmental Biology R-HSA-1266738
Stabilization of p53 R-HSA-69541
Switching of origins to a post-replicative state R-HSA-69052
Ub-specific processing proteases R-HSA-5689880
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 signaling R-HSA-9020702
RAF/MAP kinase cascade R-HSA-5673001
Intracellular signaling by second messengers R-HSA-9006925
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disorders of transmembrane transporters R-HSA-5619115
Immune System R-HSA-168256
Cellular responses to stress R-HSA-2262752
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by ROBO receptors R-HSA-376176
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nuclear events mediated by NFE2L2 R-HSA-9759194
Infectious disease R-HSA-5663205
PCP/CE pathway R-HSA-4086400
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stimuli R-HSA-8953897
Apoptosis R-HSA-109581
Cellular response to hypoxia R-HSA-1234174
Regulation of RUNX3 expression and activity R-HSA-8941858
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCR signaling R-HSA-202403
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
ABC transporter disorders R-HSA-5619084
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of RNA R-HSA-8953854
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Dependent G1 DNA Damage Response R-HSA-69563
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle R-HSA-1640170
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G2-G2/M phases R-HSA-453274
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Mitotic Anaphase R-HSA-68882
Switching of origins to a post-replicative state R-HSA-69052
HIV Infection R-HSA-162906
RNA Polymerase II Transcription R-HSA-73857
DNA Replication Pre-Initiation R-HSA-69002
Signaling by Interleukins R-HSA-449147
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog 'on' state R-HSA-5632684
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 signaling R-HSA-9020702
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Programmed Cell Death R-HSA-5357801
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
MAPK6/MAPK4 signaling R-HSA-5687128
Neddylation R-HSA-8951664
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TCF dependent signaling in response to WNT R-HSA-201681
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX3 R-HSA-8878159
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Generic Transcription Pathway R-HSA-212436
Signaling by WNT R-HSA-195721
Antigen processing-Cross presentation R-HSA-1236975
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of GLI1 by the proteasome R-HSA-5610780
Ub-specific processing proteases R-HSA-5689880
PTEN Regulation R-HSA-6807070
G2/M Transition R-HSA-69275
S Phase R-HSA-69242
RAF/MAP kinase cascade R-HSA-5673001
Deubiquitination R-HSA-5688426
Degradation of DVL R-HSA-4641258
Axon guidance R-HSA-422475
UCH proteinases R-HSA-5689603
Orc1 removal from chromatin R-HSA-68949
Hedgehog 'off' state R-HSA-5610787
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S Transition R-HSA-69206
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Developmental Biology R-HSA-1266738
Metabolism of proteins R-HSA-392499
p53-Independent DNA Damage Response R-HSA-69610
M Phase R-HSA-68886
Metabolism of polyamines R-HSA-351202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH R-HSA-157118
Separation of Sister Chromatids R-HSA-2467813
Cell Cycle, Mitotic R-HSA-69278
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Vif-mediated degradation of APOBEC3G R-HSA-180585
Interleukin-1 family signaling R-HSA-446652
ER-Phagosome pathway R-HSA-1236974
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Innate Immune System R-HSA-168249
Vpu mediated degradation of CD4 R-HSA-180534
Assembly of the pre-replicative complex R-HSA-68867
G2/M Checkpoints R-HSA-69481
Intracellular signaling by second messengers R-HSA-9006925
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Stabilization of p53 R-HSA-69541
Signaling by NOTCH4 R-HSA-9013694
Cyclin E associated events during G1/S transition R-HSA-69202
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
DNA Replication R-HSA-69306
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by Hedgehog R-HSA-5358351
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Activation of NF-kappaB in B cells R-HSA-1169091
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle Checkpoints R-HSA-69620
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G2/M Checkpoints R-HSA-69481
Degradation of beta-catenin by the destruction complex R-HSA-195253
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing-Cross presentation R-HSA-1236975
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of polyamines R-HSA-351202
Signaling by NOTCH R-HSA-157118
Programmed Cell Death R-HSA-5357801
Apoptosis R-HSA-109581
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Stabilization of p53 R-HSA-69541
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Metaphase and Anaphase R-HSA-2555396
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
UCH proteinases R-HSA-5689603
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
M Phase R-HSA-68886
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
PCP/CE pathway R-HSA-4086400
Innate Immune System R-HSA-168249
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of Apoptosis R-HSA-169911
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Degradation of DVL R-HSA-4641258
G2/M Transition R-HSA-69275
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent DNA Damage Response R-HSA-69610
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Anaphase R-HSA-68882
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Nuclear events mediated by NFE2L2 R-HSA-9759194
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of proteins R-HSA-392499
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism R-HSA-1430728
Signaling by ROBO receptors R-HSA-376176
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Regulation of RAS by GAPs R-HSA-5658442
Generic Transcription Pathway R-HSA-212436
Vif-mediated degradation of APOBEC3G R-HSA-180585
G1/S DNA Damage Checkpoints R-HSA-69615
Deubiquitination R-HSA-5688426
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Negative regulation of NOTCH4 signaling R-HSA-9604323
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular response to hypoxia R-HSA-1234174
MAPK6/MAPK4 signaling R-HSA-5687128
Switching of origins to a post-replicative state R-HSA-69052
Signaling by WNT R-HSA-195721
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S Transition R-HSA-69206
Activation of NF-kappaB in B cells R-HSA-1169091
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stimuli R-HSA-8953897
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Interleukins R-HSA-449147
Ub-specific processing proteases R-HSA-5689880
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Hedgehog 'off' state R-HSA-5610787
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Orc1 removal from chromatin R-HSA-68949
KEAP1-NFE2L2 pathway R-HSA-9755511
Assembly of the pre-replicative complex R-HSA-68867
Axon guidance R-HSA-422475
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Immune System R-HSA-168256
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by NOTCH4 R-HSA-9013694
Degradation of GLI2 by the proteasome R-HSA-5610783
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cell Cycle R-HSA-1640170
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HIV Infection R-HSA-162906
Signaling by Hedgehog R-HSA-5358351
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
Hh mutants abrogate ligand secretion R-HSA-5387390
Signal Transduction R-HSA-162582
Cellular response to chemical stress R-HSA-9711123
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RUNX2 expression and activity R-HSA-8939902
Downstream TCR signaling R-HSA-202424
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of AXIN R-HSA-4641257
Separation of Sister Chromatids R-HSA-2467813
Disorders of transmembrane transporters R-HSA-5619115
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of RUNX3 expression and activity R-HSA-8941858
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of RNA R-HSA-8953854
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle R-HSA-1640170
DNA Replication R-HSA-69306
Transport of small molecules R-HSA-382551
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of polyamines R-HSA-351202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by WNT R-HSA-195721
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle, Mitotic R-HSA-69278
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Checkpoints R-HSA-69481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
Apoptosis R-HSA-109581
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
Innate Immune System R-HSA-168249
G1/S Transition R-HSA-69206
Metabolism of proteins R-HSA-392499
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Hh mutants are degraded by ERAD R-HSA-5362768
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
Signaling by the B Cell Receptor (BCR) R-HSA-983705
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK family signaling cascades R-HSA-5683057
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ER-Phagosome pathway R-HSA-1236974
Infectious disease R-HSA-5663205
PTEN Regulation R-HSA-6807070
ABC transporter disorders R-HSA-5619084
HIV Infection R-HSA-162906
PCP/CE pathway R-HSA-4086400
Orc1 removal from chromatin R-HSA-68949
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
M Phase R-HSA-68886
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism R-HSA-1430728
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX1 R-HSA-8878171
KEAP1-NFE2L2 pathway R-HSA-9755511
Switching of origins to a post-replicative state R-HSA-69052
Degradation of GLI1 by the proteasome R-HSA-5610780
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
TCR signaling R-HSA-202403
Regulation of PTEN stability and activity R-HSA-8948751
Cellular responses to stress R-HSA-2262752
G2/M Transition R-HSA-69275
Signal Transduction R-HSA-162582
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular response to chemical stress R-HSA-9711123
Host Interactions of HIV factors R-HSA-162909
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Assembly of the pre-replicative complex R-HSA-68867
RAF/MAP kinase cascade R-HSA-5673001
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of Apoptosis R-HSA-169911
Disorders of transmembrane transporters R-HSA-5619115
Stabilization of p53 R-HSA-69541
Hedgehog ligand biogenesis R-HSA-5358346
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by NOTCH R-HSA-157118
Intracellular signaling by second messengers R-HSA-9006925
Programmed Cell Death R-HSA-5357801
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
UCH proteinases R-HSA-5689603
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC-family proteins mediated transport R-HSA-382556
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 signaling R-HSA-9020702
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH4 R-HSA-9013694
Regulation of RAS by GAPs R-HSA-5658442
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vpu mediated degradation of CD4 R-HSA-180534
Gene expression (Transcription) R-HSA-74160
Ub-specific processing proteases R-HSA-5689880
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Anaphase R-HSA-68882
Degradation of AXIN R-HSA-4641257
Signaling by Interleukins R-HSA-449147
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX3 expression and activity R-HSA-8941858
Developmental Biology R-HSA-1266738
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK1/MAPK3 signaling R-HSA-5684996
FCERI mediated NF-kB activation R-HSA-2871837
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by ROBO receptors R-HSA-376176
Degradation of DVL R-HSA-4641258
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
p53-Independent DNA Damage Response R-HSA-69610
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK6/MAPK4 signaling R-HSA-5687128
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Generic Transcription Pathway R-HSA-212436
Synthesis of DNA R-HSA-69239
Deubiquitination R-HSA-5688426
Cellular responses to stimuli R-HSA-8953897
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Post-translational protein modification R-HSA-597592
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
Neddylation R-HSA-8951664
DNA Replication Pre-Initiation R-HSA-69002
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin E associated events during G1/S transition R-HSA-69202
Axon guidance R-HSA-422475
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Downstream TCR signaling R-HSA-202424
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Negative regulation of NOTCH4 signaling R-HSA-9604323

Expression Atlas ENSG00000126067
NCBI gene (formerly Entrezgene) 5690
GeneCards 9539
HGNC Symbol HGNC:9539
MIM gene 602175
UniProtKB Gene Name P49721
WikiGene 5690
Gene: PSMC3
Ensembl ID : ENSG00000165916
Description: proteasome 26S subunit, ATPase 3
Gene Synonyms: RPT5,TBP-1,TBP1
5 APIs:
218 Possible Orthologues:

Mitotic Anaphase R-HSA-68882
Apoptosis R-HSA-109581
Infectious disease R-HSA-5663205
G2/M Checkpoints R-HSA-69481
Hh mutants are degraded by ERAD R-HSA-5362768
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX2 R-HSA-8878166
Orc1 removal from chromatin R-HSA-68949
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Independent DNA Damage Response R-HSA-69610
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Innate Immune System R-HSA-168249
Negative regulation of NOTCH4 signaling R-HSA-9604323
S Phase R-HSA-69242
Cell Cycle, Mitotic R-HSA-69278
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic G2-G2/M phases R-HSA-453274
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog 'off' state R-HSA-5610787
p53-Dependent G1 DNA Damage Response R-HSA-69563
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
UCH proteinases R-HSA-5689603
Neutrophil degranulation R-HSA-6798695
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 signaling R-HSA-9020702
ABC transporter disorders R-HSA-5619084
Regulation of RAS by GAPs R-HSA-5658442
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Developmental Biology R-HSA-1266738
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of GLI1 by the proteasome R-HSA-5610780
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism R-HSA-1430728
Downstream TCR signaling R-HSA-202424
G1/S DNA Damage Checkpoints R-HSA-69615
FCERI mediated NF-kB activation R-HSA-2871837
G1/S Transition R-HSA-69206
Separation of Sister Chromatids R-HSA-2467813
MAPK6/MAPK4 signaling R-HSA-5687128
Post-translational protein modification R-HSA-597592
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of RNA R-HSA-8953854
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of AXIN R-HSA-4641257
Cellular responses to stimuli R-HSA-8953897
PTEN Regulation R-HSA-6807070
Disorders of transmembrane transporters R-HSA-5619115
M Phase R-HSA-68886
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Vpu mediated degradation of CD4 R-HSA-180534
Cellular response to hypoxia R-HSA-1234174
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PCP/CE pathway R-HSA-4086400
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
Axon guidance R-HSA-422475
Degradation of GLI2 by the proteasome R-HSA-5610783
Mitotic G1 phase and G1/S transition R-HSA-453279
HIV Infection R-HSA-162906
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of Apoptosis R-HSA-169911
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PIP3 activates AKT signaling R-HSA-1257604
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of NF-kappaB in B cells R-HSA-1169091
Hh mutants abrogate ligand secretion R-HSA-5387390
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by ROBO receptors R-HSA-376176
Cyclin E associated events during G1/S transition R-HSA-69202
Adaptive Immune System R-HSA-1280218
Hedgehog 'on' state R-HSA-5632684
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
KEAP1-NFE2L2 pathway R-HSA-9755511
Nuclear events mediated by NFE2L2 R-HSA-9759194
RAF/MAP kinase cascade R-HSA-5673001
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Switching of origins to a post-replicative state R-HSA-69052
Assembly of the pre-replicative complex R-HSA-68867
Signaling by Hedgehog R-HSA-5358351
DNA Replication R-HSA-69306
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Synthesis of DNA R-HSA-69239
Immune System R-HSA-168256
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Transition R-HSA-69275
ABC-family proteins mediated transport R-HSA-382556
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nervous system development R-HSA-9675108
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
DNA Replication Pre-Initiation R-HSA-69002
Transport of small molecules R-HSA-382551
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX1 R-HSA-8878171
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stimuli R-HSA-8953897
Signaling by ROBO receptors R-HSA-376176
Post-translational protein modification R-HSA-597592
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH4 R-HSA-9013694
DNA Replication R-HSA-69306
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Regulation of Apoptosis R-HSA-169911
RNA Polymerase II Transcription R-HSA-73857
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of DVL R-HSA-4641258
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G2-G2/M phases R-HSA-453274
Transcriptional regulation by RUNX1 R-HSA-8878171
UCH proteinases R-HSA-5689603
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX2 expression and activity R-HSA-8939902
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Axon guidance R-HSA-422475
G1/S DNA Damage Checkpoints R-HSA-69615
Neutrophil degranulation R-HSA-6798695
Disorders of transmembrane transporters R-HSA-5619115
TCR signaling R-HSA-202403
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
ABC transporter disorders R-HSA-5619084
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
PCP/CE pathway R-HSA-4086400
Switching of origins to a post-replicative state R-HSA-69052
Deubiquitination R-HSA-5688426
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Beta-catenin independent WNT signaling R-HSA-3858494
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transport of small molecules R-HSA-382551
Neddylation R-HSA-8951664
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
ABC-family proteins mediated transport R-HSA-382556
Downstream TCR signaling R-HSA-202424
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants are degraded by ERAD R-HSA-5362768
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RAF/MAP kinase cascade R-HSA-5673001
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stress R-HSA-2262752
Interleukin-1 signaling R-HSA-9020702
MAPK6/MAPK4 signaling R-HSA-5687128
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of polyamines R-HSA-351202
Apoptosis R-HSA-109581
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Immune System R-HSA-168256
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
MAPK family signaling cascades R-HSA-5683057
Disease R-HSA-1643685
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Mitotic Anaphase R-HSA-68882
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 family signaling R-HSA-446652
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH R-HSA-157118
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
M Phase R-HSA-68886
Regulation of PTEN stability and activity R-HSA-8948751
Ub-specific processing proteases R-HSA-5689880
Antigen processing-Cross presentation R-HSA-1236975
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
TCF dependent signaling in response to WNT R-HSA-201681
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of RNA R-HSA-8953854
Metabolism R-HSA-1430728
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by WNT R-HSA-195721
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'off' state R-HSA-5610787
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Class I MHC mediated antigen processing & presentation R-HSA-983169
ER-Phagosome pathway R-HSA-1236974
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
Stabilization of p53 R-HSA-69541
p53-Independent DNA Damage Response R-HSA-69610
Synthesis of DNA R-HSA-69239
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle, Mitotic R-HSA-69278
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of AXIN R-HSA-4641257
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Hedgehog R-HSA-5358351
Degradation of beta-catenin by the destruction complex R-HSA-195253
Generic Transcription Pathway R-HSA-212436
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
HIV Infection R-HSA-162906
Programmed Cell Death R-HSA-5357801
Negative regulation of NOTCH4 signaling R-HSA-9604323
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX3 R-HSA-8878159
Gene expression (Transcription) R-HSA-74160
Hh mutants abrogate ligand secretion R-HSA-5387390
Separation of Sister Chromatids R-HSA-2467813
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog 'on' state R-HSA-5632684
ER-Phagosome pathway R-HSA-1236974
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Generic Transcription Pathway R-HSA-212436
Degradation of GLI1 by the proteasome R-HSA-5610780
Mitotic Anaphase R-HSA-68882
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by Hedgehog R-HSA-5358351
Synthesis of DNA R-HSA-69239
RAF/MAP kinase cascade R-HSA-5673001
Disorders of transmembrane transporters R-HSA-5619115
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Developmental Biology R-HSA-1266738
Degradation of beta-catenin by the destruction complex R-HSA-195253
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PIP3 activates AKT signaling R-HSA-1257604
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transcriptional regulation by RUNX1 R-HSA-8878171
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular response to chemical stress R-HSA-9711123
Axon guidance R-HSA-422475
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Neddylation R-HSA-8951664
Mitotic G2-G2/M phases R-HSA-453274
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Infectious disease R-HSA-5663205
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Gene expression (Transcription) R-HSA-74160
Downstream TCR signaling R-HSA-202424
Class I MHC mediated antigen processing & presentation R-HSA-983169
Host Interactions of HIV factors R-HSA-162909
Intracellular signaling by second messengers R-HSA-9006925
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
PCP/CE pathway R-HSA-4086400
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular response to hypoxia R-HSA-1234174
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of Apoptosis R-HSA-169911
Metabolism of proteins R-HSA-392499
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism R-HSA-1430728
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S Transition R-HSA-69206
Signaling by NOTCH4 R-HSA-9013694
ABC transporter disorders R-HSA-5619084
Beta-catenin independent WNT signaling R-HSA-3858494
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RAS by GAPs R-HSA-5658442
Activation of NF-kappaB in B cells R-HSA-1169091
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
Assembly of the pre-replicative complex R-HSA-68867
Immune System R-HSA-168256
Transcriptional regulation by RUNX3 R-HSA-8878159
Hh mutants abrogate ligand secretion R-HSA-5387390
M Phase R-HSA-68886
Signaling by WNT R-HSA-195721
Deubiquitination R-HSA-5688426
Cellular responses to stimuli R-HSA-8953897
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
HIV Infection R-HSA-162906
Adaptive Immune System R-HSA-1280218
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
Hh mutants are degraded by ERAD R-HSA-5362768
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Nervous system development R-HSA-9675108
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of polyamines R-HSA-351202
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
Cytokine Signaling in Immune system R-HSA-1280215
UCH proteinases R-HSA-5689603
TCR signaling R-HSA-202403
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'on' state R-HSA-5632684
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of RUNX2 expression and activity R-HSA-8939902
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Vpu mediated degradation of CD4 R-HSA-180534
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Signaling by ROBO receptors R-HSA-376176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Interleukins R-HSA-449147
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle R-HSA-1640170
DNA Replication R-HSA-69306
Regulation of PTEN stability and activity R-HSA-8948751
MAPK1/MAPK3 signaling R-HSA-5684996
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Degradation of DVL R-HSA-4641258
Ub-specific processing proteases R-HSA-5689880
Hedgehog 'off' state R-HSA-5610787
Innate Immune System R-HSA-168249
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Neutrophil degranulation R-HSA-6798695
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK family signaling cascades R-HSA-5683057
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
G1/S DNA Damage Checkpoints R-HSA-69615
Disease R-HSA-1643685
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Cell Cycle Checkpoints R-HSA-69620
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Asymmetric localization of PCP proteins R-HSA-4608870
RNA Polymerase II Transcription R-HSA-73857
Orc1 removal from chromatin R-HSA-68949
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PTEN Regulation R-HSA-6807070
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of AXIN R-HSA-4641257
MAPK family signaling cascades R-HSA-5683057
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'off' state R-HSA-5610787
ABC-family proteins mediated transport R-HSA-382556
Signaling by NOTCH4 R-HSA-9013694
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hedgehog ligand biogenesis R-HSA-5358346
Disorders of transmembrane transporters R-HSA-5619115
Transcriptional regulation by RUNX1 R-HSA-8878171
Downstream TCR signaling R-HSA-202424
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Interleukin-1 signaling R-HSA-9020702
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Assembly of the pre-replicative complex R-HSA-68867
Intracellular signaling by second messengers R-HSA-9006925
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Hedgehog R-HSA-5358351
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX3 R-HSA-8878159
Developmental Biology R-HSA-1266738
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle Checkpoints R-HSA-69620
Cellular response to chemical stress R-HSA-9711123
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mitotic cell cycle R-HSA-453276
G1/S Transition R-HSA-69206
MAPK1/MAPK3 signaling R-HSA-5684996
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Neutrophil degranulation R-HSA-6798695
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
G2/M Transition R-HSA-69275
Hh mutants are degraded by ERAD R-HSA-5362768
Post-translational protein modification R-HSA-597592
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
C-type lectin receptors (CLRs) R-HSA-5621481
FCERI mediated NF-kB activation R-HSA-2871837
Synthesis of DNA R-HSA-69239
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Dependent G1 DNA Damage Response R-HSA-69563
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hh mutants abrogate ligand secretion R-HSA-5387390
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'on' state R-HSA-5632684
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
Interleukin-1 family signaling R-HSA-446652
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transport of small molecules R-HSA-382551
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of AXIN R-HSA-4641257
Cellular response to hypoxia R-HSA-1234174
p53-Independent DNA Damage Response R-HSA-69610
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Gene expression (Transcription) R-HSA-74160
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
Host Interactions of HIV factors R-HSA-162909
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of NF-kappaB in B cells R-HSA-1169091
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Switching of origins to a post-replicative state R-HSA-69052
Programmed Cell Death R-HSA-5357801
Metabolism of RNA R-HSA-8953854
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Signaling by the B Cell Receptor (BCR) R-HSA-983705
UCH proteinases R-HSA-5689603
Cell Cycle R-HSA-1640170
Cellular responses to stimuli R-HSA-8953897
Regulation of Apoptosis R-HSA-169911
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of RUNX3 expression and activity R-HSA-8941858
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Defective CFTR causes cystic fibrosis R-HSA-5678895
Orc1 removal from chromatin R-HSA-68949
Class I MHC mediated antigen processing & presentation R-HSA-983169
Stabilization of p53 R-HSA-69541
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of DVL R-HSA-4641258
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of polyamines R-HSA-351202
Apoptosis R-HSA-109581
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transcriptional regulation by RUNX2 R-HSA-8878166
ABC transporter disorders R-HSA-5619084
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Adaptive Immune System R-HSA-1280218
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI2 by the proteasome R-HSA-5610783
Cellular responses to stress R-HSA-2262752
HIV Infection R-HSA-162906
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G2/M Checkpoints R-HSA-69481
Signaling by WNT R-HSA-195721
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
Separation of Sister Chromatids R-HSA-2467813
Antigen processing-Cross presentation R-HSA-1236975
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication Pre-Initiation R-HSA-69002
PCP/CE pathway R-HSA-4086400
Nuclear events mediated by NFE2L2 R-HSA-9759194
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of polyamines R-HSA-351202
Intracellular signaling by second messengers R-HSA-9006925
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of AXIN R-HSA-4641257
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Neutrophil degranulation R-HSA-6798695
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
Generic Transcription Pathway R-HSA-212436
ER-Phagosome pathway R-HSA-1236974
Disorders of transmembrane transporters R-HSA-5619115
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Gene expression (Transcription) R-HSA-74160
Degradation of beta-catenin by the destruction complex R-HSA-195253
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transport of small molecules R-HSA-382551
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism of amino acids and derivatives R-HSA-71291
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RAS by GAPs R-HSA-5658442
Signaling by ROBO receptors R-HSA-376176
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by Interleukins R-HSA-449147
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Signaling by WNT R-HSA-195721
RNA Polymerase II Transcription R-HSA-73857
Programmed Cell Death R-HSA-5357801
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signal Transduction R-HSA-162582
Switching of origins to a post-replicative state R-HSA-69052
TCF dependent signaling in response to WNT R-HSA-201681
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FCERI mediated NF-kB activation R-HSA-2871837
TCR signaling R-HSA-202403
G2/M Checkpoints R-HSA-69481
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
S Phase R-HSA-69242
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'on' state R-HSA-5632684
PCP/CE pathway R-HSA-4086400
Negative regulation of NOTCH4 signaling R-HSA-9604323
HIV Infection R-HSA-162906
DNA Replication R-HSA-69306
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle, Mitotic R-HSA-69278
Signaling by Hedgehog R-HSA-5358351
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RUNX3 expression and activity R-HSA-8941858
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
M Phase R-HSA-68886
Adaptive Immune System R-HSA-1280218
Cell Cycle R-HSA-1640170
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI2 by the proteasome R-HSA-5610783
Infectious disease R-HSA-5663205
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
Assembly of the pre-replicative complex R-HSA-68867
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transcriptional regulation by RUNX3 R-HSA-8878159
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC transporter disorders R-HSA-5619084
Interleukin-1 family signaling R-HSA-446652
Mitotic G2-G2/M phases R-HSA-453274
Activation of NF-kappaB in B cells R-HSA-1169091
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Mitotic Anaphase R-HSA-68882
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism R-HSA-1430728
Signaling by NOTCH R-HSA-157118
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI1 by the proteasome R-HSA-5610780
Degradation of DVL R-HSA-4641258
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog ligand biogenesis R-HSA-5358346
Developmental Biology R-HSA-1266738
p53-Independent DNA Damage Response R-HSA-69610
G2/M Transition R-HSA-69275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Post-translational protein modification R-HSA-597592
MAPK1/MAPK3 signaling R-HSA-5684996
Axon guidance R-HSA-422475
Regulation of mitotic cell cycle R-HSA-453276
Vpu mediated degradation of CD4 R-HSA-180534
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX1 R-HSA-8878171
Stabilization of p53 R-HSA-69541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cell Cycle Checkpoints R-HSA-69620
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to hypoxia R-HSA-1234174
G1/S Transition R-HSA-69206
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Immune System R-HSA-168256
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism of RNA R-HSA-8953854
Hh mutants abrogate ligand secretion R-HSA-5387390
Nervous system development R-HSA-9675108
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK family signaling cascades R-HSA-5683057
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
PTEN Regulation R-HSA-6807070
Innate Immune System R-HSA-168249
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of proteins R-HSA-392499
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of Apoptosis R-HSA-169911
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G1/S DNA Damage Checkpoints R-HSA-69615
C-type lectin receptors (CLRs) R-HSA-5621481
DNA Replication Pre-Initiation R-HSA-69002
Cyclin E associated events during G1/S transition R-HSA-69202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
Disease R-HSA-1643685
Hedgehog 'off' state R-HSA-5610787
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cytokine Signaling in Immune system R-HSA-1280215
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
HIV Infection R-HSA-162906
DNA Replication R-HSA-69306
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by ROBO receptors R-HSA-376176
Apoptosis R-HSA-109581
Ub-specific processing proteases R-HSA-5689880
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of RNA R-HSA-8953854
Hedgehog 'on' state R-HSA-5632684
M Phase R-HSA-68886
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic Anaphase R-HSA-68882
Cellular response to chemical stress R-HSA-9711123
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Transition R-HSA-69275
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by NOTCH R-HSA-157118
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G2-G2/M phases R-HSA-453274
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing-Cross presentation R-HSA-1236975
Downstream TCR signaling R-HSA-202424
RAF/MAP kinase cascade R-HSA-5673001
Programmed Cell Death R-HSA-5357801
Stabilization of p53 R-HSA-69541
Cell Cycle Checkpoints R-HSA-69620
Gene expression (Transcription) R-HSA-74160
Separation of Sister Chromatids R-HSA-2467813
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ER-Phagosome pathway R-HSA-1236974
Asymmetric localization of PCP proteins R-HSA-4608870
Axon guidance R-HSA-422475
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX3 R-HSA-8878159
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle, Mitotic R-HSA-69278
Regulation of mitotic cell cycle R-HSA-453276
UCH proteinases R-HSA-5689603
TCR signaling R-HSA-202403
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
ABC-family proteins mediated transport R-HSA-382556
Signaling by Hedgehog R-HSA-5358351
Transport of small molecules R-HSA-382551
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX2 R-HSA-8878166
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Degradation of AXIN R-HSA-4641257
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Neutrophil degranulation R-HSA-6798695
Infectious disease R-HSA-5663205
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Independent DNA Damage Response R-HSA-69610
Orc1 removal from chromatin R-HSA-68949
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of RAS by GAPs R-HSA-5658442
Signal Transduction R-HSA-162582
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'off' state R-HSA-5610787
MAPK1/MAPK3 signaling R-HSA-5684996
Generic Transcription Pathway R-HSA-212436
ABC transporter disorders R-HSA-5619084
Post-translational protein modification R-HSA-597592
Regulation of PTEN stability and activity R-HSA-8948751
MAPK family signaling cascades R-HSA-5683057
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of Apoptosis R-HSA-169911
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of polyamines R-HSA-351202
Signaling by Interleukins R-HSA-449147
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vif-mediated degradation of APOBEC3G R-HSA-180585
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI2 by the proteasome R-HSA-5610783
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH4 R-HSA-9013694
Innate Immune System R-HSA-168249
G1/S Transition R-HSA-69206
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants abrogate ligand secretion R-HSA-5387390
Nervous system development R-HSA-9675108
Degradation of DVL R-HSA-4641258
PTEN Regulation R-HSA-6807070
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
FCERI mediated NF-kB activation R-HSA-2871837
Cellular responses to stress R-HSA-2262752
Hedgehog ligand biogenesis R-HSA-5358346
CLEC7A (Dectin-1) signaling R-HSA-5607764
Immune System R-HSA-168256
Regulation of RUNX2 expression and activity R-HSA-8939902
Developmental Biology R-HSA-1266738
Deubiquitination R-HSA-5688426
Interleukin-1 signaling R-HSA-9020702
Synthesis of DNA R-HSA-69239
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
p53-Dependent G1 DNA Damage Response R-HSA-69563
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Assembly of the pre-replicative complex R-HSA-68867
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of Apoptosis R-HSA-169911
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Intracellular signaling by second messengers R-HSA-9006925
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of AXIN R-HSA-4641257
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of proteins R-HSA-392499
ABC-family proteins mediated transport R-HSA-382556
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
Generic Transcription Pathway R-HSA-212436
Cyclin E associated events during G1/S transition R-HSA-69202
HIV Infection R-HSA-162906
Cellular response to hypoxia R-HSA-1234174
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX2 R-HSA-8878166
Disorders of transmembrane transporters R-HSA-5619115
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Post-translational protein modification R-HSA-597592
Degradation of DVL R-HSA-4641258
Separation of Sister Chromatids R-HSA-2467813
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G1/S DNA Damage Checkpoints R-HSA-69615
UCH proteinases R-HSA-5689603
Mitotic Anaphase R-HSA-68882
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Neutrophil degranulation R-HSA-6798695
RNA Polymerase II Transcription R-HSA-73857
G1/S Transition R-HSA-69206
Regulation of RUNX2 expression and activity R-HSA-8939902
DNA Replication Pre-Initiation R-HSA-69002
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Nervous system development R-HSA-9675108
Transport of small molecules R-HSA-382551
Developmental Biology R-HSA-1266738
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
Orc1 removal from chromatin R-HSA-68949
Cell Cycle Checkpoints R-HSA-69620
S Phase R-HSA-69242
Hh mutants abrogate ligand secretion R-HSA-5387390
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX3 expression and activity R-HSA-8941858
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by ROBO receptors R-HSA-376176
Stabilization of p53 R-HSA-69541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
Degradation of beta-catenin by the destruction complex R-HSA-195253
M Phase R-HSA-68886
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream TCR signaling R-HSA-202424
Antigen processing-Cross presentation R-HSA-1236975
Hh mutants are degraded by ERAD R-HSA-5362768
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PIP3 activates AKT signaling R-HSA-1257604
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK1/MAPK3 signaling R-HSA-5684996
ABC transporter disorders R-HSA-5619084
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mitotic cell cycle R-HSA-453276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
CLEC7A (Dectin-1) signaling R-HSA-5607764
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
Transcriptional regulation by RUNX3 R-HSA-8878159
Hedgehog 'off' state R-HSA-5610787
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH4 R-HSA-9013694
Hedgehog 'on' state R-HSA-5632684
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
Neddylation R-HSA-8951664
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to chemical stress R-HSA-9711123
Metabolism of RNA R-HSA-8953854
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
Gene expression (Transcription) R-HSA-74160
Metabolism of polyamines R-HSA-351202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Hedgehog R-HSA-5358351
Cell Cycle, Mitotic R-HSA-69278
ER-Phagosome pathway R-HSA-1236974
Host Interactions of HIV factors R-HSA-162909
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RAS by GAPs R-HSA-5658442
Cytokine Signaling in Immune system R-HSA-1280215
Deubiquitination R-HSA-5688426
PTEN Regulation R-HSA-6807070
Signaling by NOTCH R-HSA-157118
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by Interleukins R-HSA-449147
Degradation of GLI1 by the proteasome R-HSA-5610780
TCR signaling R-HSA-202403
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Innate Immune System R-HSA-168249
Beta-catenin independent WNT signaling R-HSA-3858494
Interleukin-1 signaling R-HSA-9020702
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Ub-specific processing proteases R-HSA-5689880
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle R-HSA-1640170
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'on' state R-HSA-5632684
Metabolism of RNA R-HSA-8953854
G2/M Checkpoints R-HSA-69481
ABC transporter disorders R-HSA-5619084
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RUNX2 expression and activity R-HSA-8939902
Assembly of the pre-replicative complex R-HSA-68867
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MAPK1/MAPK3 signaling R-HSA-5684996
Deubiquitination R-HSA-5688426
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX3 R-HSA-8878159
Developmental Biology R-HSA-1266738
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic Anaphase R-HSA-68882
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Beta-catenin independent WNT signaling R-HSA-3858494
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of GLI2 by the proteasome R-HSA-5610783
Disorders of transmembrane transporters R-HSA-5619115
Neutrophil degranulation R-HSA-6798695
Cell Cycle Checkpoints R-HSA-69620
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Apoptosis R-HSA-109581
Asymmetric localization of PCP proteins R-HSA-4608870
Axon guidance R-HSA-422475
Orc1 removal from chromatin R-HSA-68949
Cell Cycle, Mitotic R-HSA-69278
Hh mutants abrogate ligand secretion R-HSA-5387390
Nuclear events mediated by NFE2L2 R-HSA-9759194
Immune System R-HSA-168256
Regulation of Apoptosis R-HSA-169911
Disease R-HSA-1643685
Cellular response to hypoxia R-HSA-1234174
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cytokine Signaling in Immune system R-HSA-1280215
TCR signaling R-HSA-202403
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ER-Phagosome pathway R-HSA-1236974
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
FCERI mediated NF-kB activation R-HSA-2871837
Generic Transcription Pathway R-HSA-212436
p53-Independent DNA Damage Response R-HSA-69610
Degradation of DVL R-HSA-4641258
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog 'off' state R-HSA-5610787
Signaling by ROBO receptors R-HSA-376176
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stress R-HSA-2262752
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S DNA Damage Checkpoints R-HSA-69615
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
HIV Infection R-HSA-162906
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Nervous system development R-HSA-9675108
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Switching of origins to a post-replicative state R-HSA-69052
Degradation of AXIN R-HSA-4641257
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mitotic cell cycle R-HSA-453276
Signaling by NOTCH R-HSA-157118
Stabilization of p53 R-HSA-69541
Ub-specific processing proteases R-HSA-5689880
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
C-type lectin receptors (CLRs) R-HSA-5621481
Downstream TCR signaling R-HSA-202424
Metabolism of polyamines R-HSA-351202
Cyclin E associated events during G1/S transition R-HSA-69202
RAF/MAP kinase cascade R-HSA-5673001
S Phase R-HSA-69242
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by WNT R-HSA-195721
Signaling by NOTCH4 R-HSA-9013694
Synthesis of DNA R-HSA-69239
Class I MHC mediated antigen processing & presentation R-HSA-983169
Post-translational protein modification R-HSA-597592
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog ligand biogenesis R-HSA-5358346
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hh mutants are degraded by ERAD R-HSA-5362768
Gene expression (Transcription) R-HSA-74160
Regulation of PTEN stability and activity R-HSA-8948751
M Phase R-HSA-68886
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
UCH proteinases R-HSA-5689603
Interleukin-1 family signaling R-HSA-446652
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular responses to stimuli R-HSA-8953897
Regulation of RAS by GAPs R-HSA-5658442
G1/S Transition R-HSA-69206
PCP/CE pathway R-HSA-4086400
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cell Cycle R-HSA-1640170
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G2/M Transition R-HSA-69275
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1 DNA Damage Response R-HSA-69563
Infectious disease R-HSA-5663205
Antigen processing-Cross presentation R-HSA-1236975
Signal Transduction R-HSA-162582
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transport of small molecules R-HSA-382551
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RUNX3 expression and activity R-HSA-8941858
G2/M Transition R-HSA-69275
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
Interleukin-1 signaling R-HSA-9020702
Regulation of RUNX2 expression and activity R-HSA-8939902
TCR signaling R-HSA-202403
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of GLI2 by the proteasome R-HSA-5610783
Infectious disease R-HSA-5663205
Signaling by ROBO receptors R-HSA-376176
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cytokine Signaling in Immune system R-HSA-1280215
Orc1 removal from chromatin R-HSA-68949
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PTEN Regulation R-HSA-6807070
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Developmental Biology R-HSA-1266738
G2/M Checkpoints R-HSA-69481
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
G1/S Transition R-HSA-69206
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog ligand biogenesis R-HSA-5358346
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Disease R-HSA-1643685
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH R-HSA-157118
UCH proteinases R-HSA-5689603
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing-Cross presentation R-HSA-1236975
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cell Cycle R-HSA-1640170
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
RAF/MAP kinase cascade R-HSA-5673001
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ABC-family proteins mediated transport R-HSA-382556
M Phase R-HSA-68886
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Generic Transcription Pathway R-HSA-212436
Synthesis of DNA R-HSA-69239
Cell Cycle, Mitotic R-HSA-69278
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signal Transduction R-HSA-162582
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of RNA R-HSA-8953854
PIP3 activates AKT signaling R-HSA-1257604
DNA Replication R-HSA-69306
Assembly of the pre-replicative complex R-HSA-68867
Regulation of Apoptosis R-HSA-169911
Disorders of transmembrane transporters R-HSA-5619115
Programmed Cell Death R-HSA-5357801
CLEC7A (Dectin-1) signaling R-HSA-5607764
Nuclear events mediated by NFE2L2 R-HSA-9759194
Stabilization of p53 R-HSA-69541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stimuli R-HSA-8953897
Cellular response to chemical stress R-HSA-9711123
Innate Immune System R-HSA-168249
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Downstream TCR signaling R-HSA-202424
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hedgehog 'off' state R-HSA-5610787
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Asymmetric localization of PCP proteins R-HSA-4608870
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Independent DNA Damage Response R-HSA-69610
Transcriptional regulation by RUNX3 R-HSA-8878159
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HIV Infection R-HSA-162906
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Class I MHC mediated antigen processing & presentation R-HSA-983169
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Neutrophil degranulation R-HSA-6798695
Mitotic G1 phase and G1/S transition R-HSA-453279
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH4 R-HSA-9013694
Signaling by WNT R-HSA-195721
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular response to hypoxia R-HSA-1234174
MAPK1/MAPK3 signaling R-HSA-5684996
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle Checkpoints R-HSA-69620
ER-Phagosome pathway R-HSA-1236974
Transport of small molecules R-HSA-382551
Degradation of AXIN R-HSA-4641257
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Mitotic Anaphase R-HSA-68882
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of polyamines R-HSA-351202
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX2 R-HSA-8878166
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
C-type lectin receptors (CLRs) R-HSA-5621481
Beta-catenin independent WNT signaling R-HSA-3858494
Neddylation R-HSA-8951664
MAPK family signaling cascades R-HSA-5683057
Post-translational protein modification R-HSA-597592
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
S Phase R-HSA-69242
Regulation of PTEN stability and activity R-HSA-8948751
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Defective CFTR causes cystic fibrosis R-HSA-5678895
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RAS by GAPs R-HSA-5658442
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
ABC transporter disorders R-HSA-5619084
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
UCH proteinases R-HSA-5689603
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of PTEN stability and activity R-HSA-8948751
MAPK1/MAPK3 signaling R-HSA-5684996
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
HIV Infection R-HSA-162906
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle, Mitotic R-HSA-69278
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of AXIN R-HSA-4641257
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication Pre-Initiation R-HSA-69002
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Beta-catenin independent WNT signaling R-HSA-3858494
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Apoptosis R-HSA-109581
Signaling by ROBO receptors R-HSA-376176
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Nervous system development R-HSA-9675108
Mitotic G2-G2/M phases R-HSA-453274
TCR signaling R-HSA-202403
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'on' state R-HSA-5632684
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH R-HSA-157118
Hedgehog ligand biogenesis R-HSA-5358346
Transport of small molecules R-HSA-382551
Cyclin E associated events during G1/S transition R-HSA-69202
Metabolism of amino acids and derivatives R-HSA-71291
M Phase R-HSA-68886
Cellular responses to stress R-HSA-2262752
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Orc1 removal from chromatin R-HSA-68949
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX3 R-HSA-8878159
Class I MHC mediated antigen processing & presentation R-HSA-983169
Deubiquitination R-HSA-5688426
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
Separation of Sister Chromatids R-HSA-2467813
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Checkpoints R-HSA-69481
ER-Phagosome pathway R-HSA-1236974
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Neddylation R-HSA-8951664
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Post-translational protein modification R-HSA-597592
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of DVL R-HSA-4641258
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PTEN Regulation R-HSA-6807070
FCERI mediated NF-kB activation R-HSA-2871837
Defective CFTR causes cystic fibrosis R-HSA-5678895
Programmed Cell Death R-HSA-5357801
PCP/CE pathway R-HSA-4086400
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by WNT R-HSA-195721
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PIP3 activates AKT signaling R-HSA-1257604
G2/M Transition R-HSA-69275
Infectious disease R-HSA-5663205
C-type lectin receptors (CLRs) R-HSA-5621481
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Innate Immune System R-HSA-168249
Regulation of mitotic cell cycle R-HSA-453276
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cell Cycle Checkpoints R-HSA-69620
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Hedgehog R-HSA-5358351
Host Interactions of HIV factors R-HSA-162909
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of polyamines R-HSA-351202
Metabolism of RNA R-HSA-8953854
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Stabilization of p53 R-HSA-69541
Interleukin-1 signaling R-HSA-9020702
Asymmetric localization of PCP proteins R-HSA-4608870
Generic Transcription Pathway R-HSA-212436
G1/S Transition R-HSA-69206
Signal Transduction R-HSA-162582
DNA Replication R-HSA-69306
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
S Phase R-HSA-69242
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of proteins R-HSA-392499
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by NOTCH4 R-HSA-9013694
Switching of origins to a post-replicative state R-HSA-69052
Metabolism R-HSA-1430728
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transcriptional regulation by RUNX2 R-HSA-8878166
Hedgehog 'off' state R-HSA-5610787
Signaling by Interleukins R-HSA-449147
Vpu mediated degradation of CD4 R-HSA-180534
Developmental Biology R-HSA-1266738
CLEC7A (Dectin-1) signaling R-HSA-5607764
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Dependent G1 DNA Damage Response R-HSA-69563
Disease R-HSA-1643685
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Ub-specific processing proteases R-HSA-5689880
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing-Cross presentation R-HSA-1236975
Degradation of GLI1 by the proteasome R-HSA-5610780
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Synthesis of DNA R-HSA-69239
Adaptive Immune System R-HSA-1280218
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of DVL R-HSA-4641258
Antigen processing-Cross presentation R-HSA-1236975
Mitotic Metaphase and Anaphase R-HSA-2555396
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic G1 phase and G1/S transition R-HSA-453279
Separation of Sister Chromatids R-HSA-2467813
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic Anaphase R-HSA-68882
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Generic Transcription Pathway R-HSA-212436
Regulation of mitotic cell cycle R-HSA-453276
Infectious disease R-HSA-5663205
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of AXIN R-HSA-4641257
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX2 R-HSA-8878166
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stimuli R-HSA-8953897
Transport of small molecules R-HSA-382551
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transcriptional regulation by RUNX3 R-HSA-8878159
C-type lectin receptors (CLRs) R-HSA-5621481
Synthesis of DNA R-HSA-69239
Stabilization of p53 R-HSA-69541
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1 DNA Damage Response R-HSA-69563
Programmed Cell Death R-HSA-5357801
Cell Cycle, Mitotic R-HSA-69278
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Deubiquitination R-HSA-5688426
Cellular responses to stress R-HSA-2262752
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
Metabolism of polyamines R-HSA-351202
Cyclin E associated events during G1/S transition R-HSA-69202
Intracellular signaling by second messengers R-HSA-9006925
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
Downstream TCR signaling R-HSA-202424
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of RUNX2 expression and activity R-HSA-8939902
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCR signaling R-HSA-202403
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle R-HSA-1640170
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH4 R-HSA-9013694
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'on' state R-HSA-5632684
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vpu mediated degradation of CD4 R-HSA-180534
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to chemical stress R-HSA-9711123
KEAP1-NFE2L2 pathway R-HSA-9755511
Innate Immune System R-HSA-168249
Beta-catenin independent WNT signaling R-HSA-3858494
p53-Independent DNA Damage Response R-HSA-69610
Immune System R-HSA-168256
ABC transporter disorders R-HSA-5619084
Metabolism R-HSA-1430728
Degradation of GLI2 by the proteasome R-HSA-5610783
MAPK6/MAPK4 signaling R-HSA-5687128
Orc1 removal from chromatin R-HSA-68949
Gene expression (Transcription) R-HSA-74160
Neddylation R-HSA-8951664
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Post-translational protein modification R-HSA-597592
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Neutrophil degranulation R-HSA-6798695
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
MAPK family signaling cascades R-HSA-5683057
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G1/S Transition R-HSA-69206
Hh mutants abrogate ligand secretion R-HSA-5387390
DNA Replication R-HSA-69306
RAF/MAP kinase cascade R-HSA-5673001
Cytokine Signaling in Immune system R-HSA-1280215
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of proteins R-HSA-392499
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RAS by GAPs R-HSA-5658442
Hh mutants are degraded by ERAD R-HSA-5362768
Hedgehog ligand biogenesis R-HSA-5358346
PCP/CE pathway R-HSA-4086400
ABC-family proteins mediated transport R-HSA-382556
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to hypoxia R-HSA-1234174
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
Interleukin-1 signaling R-HSA-9020702
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle Checkpoints R-HSA-69620
S Phase R-HSA-69242
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by Interleukins R-HSA-449147
Switching of origins to a post-replicative state R-HSA-69052
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
HIV Infection R-HSA-162906
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ub-specific processing proteases R-HSA-5689880
DNA Replication Pre-Initiation R-HSA-69002
Nuclear events mediated by NFE2L2 R-HSA-9759194
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721

Expression Atlas ENSG00000165916
NCBI gene (formerly Entrezgene) 5702
GeneCards 9549
HGNC Symbol HGNC:9549
MIM gene 186852
MIM morbid 619354
UniProtKB Gene Name R4GNH3
WikiGene 5702
Gene: PSENEN
Ensembl ID : ENSG00000205155
Description: presenilin enhancer, gamma-secretase subunit
Gene Synonyms: PEN2
5 APIs:
185 Possible Orthologues:

Signaling by ERBB4 R-HSA-1236394
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH1 R-HSA-1980143
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
p75 NTR receptor-mediated signalling R-HSA-193704
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH4 R-HSA-9013694
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Regulated proteolysis of p75NTR R-HSA-193692
Amyloid fiber formation R-HSA-977225
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH2 R-HSA-1980145
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-Ephrin signaling R-HSA-2682334
Signaling by ERBB4 R-HSA-1236394
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulated proteolysis of p75NTR R-HSA-193692
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Developmental Biology R-HSA-1266738
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH2 R-HSA-1980145
Disease R-HSA-1643685
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 R-HSA-1980143
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Amyloid fiber formation R-HSA-977225
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH4 R-HSA-9013694
Noncanonical activation of NOTCH3 R-HSA-9017802
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Axon guidance R-HSA-422475
Metabolism of proteins R-HSA-392499
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
p75 NTR receptor-mediated signalling R-HSA-193704
Nervous system development R-HSA-9675108
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH2 R-HSA-1980145
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Noncanonical activation of NOTCH3 R-HSA-9017802
Death Receptor Signaling R-HSA-73887
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
Nervous system development R-HSA-9675108
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
Nuclear signaling by ERBB4 R-HSA-1251985
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 in Cancer R-HSA-2644603
NRIF signals cell death from the nucleus R-HSA-205043
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
p75 NTR receptor-mediated signalling R-HSA-193704
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH R-HSA-157118
Regulated proteolysis of p75NTR R-HSA-193692
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
EPH-Ephrin signaling R-HSA-2682334
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear signaling by ERBB4 R-HSA-1251985
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH3 R-HSA-9012852
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH2 R-HSA-1980145
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by ERBB4 R-HSA-1236394
Amyloid fiber formation R-HSA-977225
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Death Receptor Signaling R-HSA-73887
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by ERBB4 R-HSA-1236394
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH3 R-HSA-9012852
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Death Receptor Signaling R-HSA-73887
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Regulated proteolysis of p75NTR R-HSA-193692
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH4 R-HSA-9013694
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH2 R-HSA-1980145
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 R-HSA-1980143
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Amyloid fiber formation R-HSA-977225
EPH-Ephrin signaling R-HSA-2682334
Nuclear signaling by ERBB4 R-HSA-1251985
Nuclear signaling by ERBB4 R-HSA-1251985
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
Signaling by ERBB4 R-HSA-1236394
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH3 R-HSA-9012852
Disease R-HSA-1643685
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH4 R-HSA-9013694
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Nervous system development R-HSA-9675108
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Amyloid fiber formation R-HSA-977225
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH2 R-HSA-1980145
Axon guidance R-HSA-422475
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-Ephrin signaling R-HSA-2682334
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NRIF signals cell death from the nucleus R-HSA-205043
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH R-HSA-157118
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH2 R-HSA-1980145
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH3 R-HSA-9012852
Noncanonical activation of NOTCH3 R-HSA-9017802
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nervous system development R-HSA-9675108
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Death Receptor Signaling R-HSA-73887
EPH-Ephrin signaling R-HSA-2682334
Metabolism of proteins R-HSA-392499
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Axon guidance R-HSA-422475
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NRIF signals cell death from the nucleus R-HSA-205043
Death Receptor Signaling R-HSA-73887
Disease R-HSA-1643685
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Amyloid fiber formation R-HSA-977225
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 in Cancer R-HSA-2644603
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH3 R-HSA-9012852
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signal Transduction R-HSA-162582
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by ERBB4 R-HSA-1236394
Metabolism of proteins R-HSA-392499
Signaling by NOTCH2 R-HSA-1980145
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 R-HSA-1980143
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Developmental Biology R-HSA-1266738
Noncanonical activation of NOTCH3 R-HSA-9017802
Nervous system development R-HSA-9675108
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Regulated proteolysis of p75NTR R-HSA-193692
Signal Transduction R-HSA-162582
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EPH-Ephrin signaling R-HSA-2682334
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Death Receptor Signaling R-HSA-73887
Metabolism of proteins R-HSA-392499
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH3 R-HSA-9012852
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH R-HSA-157118
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Axon guidance R-HSA-422475
Signaling by NOTCH2 R-HSA-1980145
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 R-HSA-1980143
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 in Cancer R-HSA-2644603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by NOTCH1 in Cancer R-HSA-2644603
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH R-HSA-157118
Death Receptor Signaling R-HSA-73887
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 R-HSA-1980143
Amyloid fiber formation R-HSA-977225
Disease R-HSA-1643685
Signaling by NOTCH2 R-HSA-1980145
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH3 R-HSA-9012852
Nervous system development R-HSA-9675108
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by ERBB4 R-HSA-1236394
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH4 R-HSA-9013694
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NRIF signals cell death from the nucleus R-HSA-205043
p75 NTR receptor-mediated signalling R-HSA-193704
EPH-Ephrin signaling R-HSA-2682334
Axon guidance R-HSA-422475
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Signaling by ERBB4 R-HSA-1236394
Nuclear signaling by ERBB4 R-HSA-1251985
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 in Cancer R-HSA-2644603
EPH-Ephrin signaling R-HSA-2682334
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
Disease R-HSA-1643685
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Amyloid fiber formation R-HSA-977225

Expression Atlas ENSG00000205155
LRG display in Ensembl gene LRG_222
NCBI gene (formerly Entrezgene) 55851
GeneCards 30100
HGNC Symbol HGNC:30100
MIM gene 607632
MIM morbid 613736
UniProtKB Gene Name Q9NZ42
WikiGene 55851
Gene: F10
Ensembl ID : ENSG00000126218
Description: coagulation factor X
Gene Synonyms:
10 APIs:
239 Possible Orthologues:

Hemostasis R-HSA-109582
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defective factor IX causes hemophilia B R-HSA-9668250
Defective factor IX causes thrombophilia R-HSA-9672383
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Defective F9 variant does not activate FX R-HSA-9673202
Common Pathway of Fibrin Clot Formation R-HSA-140875
Defective cofactor function of FVIIIa variant R-HSA-9672396
Metabolism of proteins R-HSA-392499
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Disease R-HSA-1643685
Post-translational protein modification R-HSA-597592
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Gamma-carboxylation of protein precursors R-HSA-159740
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor VIII causes hemophilia A R-HSA-9662001
Diseases of hemostasis R-HSA-9671793
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Disease R-HSA-1643685
Defective factor IX causes hemophilia B R-HSA-9668250
Defective factor IX causes thrombophilia R-HSA-9672383
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Defective factor VIII causes hemophilia A R-HSA-9662001
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Defective cofactor function of FVIIIa variant R-HSA-9672396
Gamma-carboxylation of protein precursors R-HSA-159740
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Defective F9 variant does not activate FX R-HSA-9673202
Common Pathway of Fibrin Clot Formation R-HSA-140875
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Diseases of hemostasis R-HSA-9671793
Hemostasis R-HSA-109582
Hemostasis R-HSA-109582
Defective F9 variant does not activate FX R-HSA-9673202
Defective factor VIII causes hemophilia A R-HSA-9662001
Disease R-HSA-1643685
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Common Pathway of Fibrin Clot Formation R-HSA-140875
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Defective factor IX causes hemophilia B R-HSA-9668250
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor IX causes thrombophilia R-HSA-9672383
Diseases of hemostasis R-HSA-9671793
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Post-translational protein modification R-HSA-597592
Gamma-carboxylation of protein precursors R-HSA-159740
Metabolism of proteins R-HSA-392499
Defective cofactor function of FVIIIa variant R-HSA-9672396
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Defective factor IX causes thrombophilia R-HSA-9672383
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Common Pathway of Fibrin Clot Formation R-HSA-140875
Hemostasis R-HSA-109582
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor VIII causes hemophilia A R-HSA-9662001
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defective cofactor function of FVIIIa variant R-HSA-9672396
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Gamma-carboxylation of protein precursors R-HSA-159740
Disease R-HSA-1643685
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Diseases of hemostasis R-HSA-9671793
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective F9 variant does not activate FX R-HSA-9673202
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Defective factor IX causes hemophilia B R-HSA-9668250
Hemostasis R-HSA-109582
Diseases of hemostasis R-HSA-9671793
Defective factor IX causes thrombophilia R-HSA-9672383
Defective cofactor function of FVIIIa variant R-HSA-9672396
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Common Pathway of Fibrin Clot Formation R-HSA-140875
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Post-translational protein modification R-HSA-597592
Defective factor IX causes hemophilia B R-HSA-9668250
Disease R-HSA-1643685
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Defective F9 variant does not activate FX R-HSA-9673202
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Defective factor VIII causes hemophilia A R-HSA-9662001
Metabolism of proteins R-HSA-392499
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Post-translational protein modification R-HSA-597592
Disease R-HSA-1643685
Defective factor IX causes hemophilia B R-HSA-9668250
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Defective F9 variant does not activate FX R-HSA-9673202
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Defective cofactor function of FVIIIa variant R-HSA-9672396
Defective factor VIII causes hemophilia A R-HSA-9662001
Defective factor IX causes thrombophilia R-HSA-9672383
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Common Pathway of Fibrin Clot Formation R-HSA-140875
Diseases of hemostasis R-HSA-9671793
Metabolism of proteins R-HSA-392499
Hemostasis R-HSA-109582
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Gamma-carboxylation of protein precursors R-HSA-159740
Common Pathway of Fibrin Clot Formation R-HSA-140875
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective cofactor function of FVIIIa variant R-HSA-9672396
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Defective factor IX causes thrombophilia R-HSA-9672383
Defective F9 variant does not activate FX R-HSA-9673202
Metabolism of proteins R-HSA-392499
Diseases of hemostasis R-HSA-9671793
Hemostasis R-HSA-109582
Disease R-HSA-1643685
Defective factor IX causes hemophilia B R-HSA-9668250
Defective factor VIII causes hemophilia A R-HSA-9662001
Post-translational protein modification R-HSA-597592
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Gamma-carboxylation of protein precursors R-HSA-159740
Hemostasis R-HSA-109582
Defective factor IX causes thrombophilia R-HSA-9672383
Defective factor IX causes hemophilia B R-HSA-9668250
Defective factor VIII causes hemophilia A R-HSA-9662001
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Disease R-HSA-1643685
Post-translational protein modification R-HSA-597592
Common Pathway of Fibrin Clot Formation R-HSA-140875
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective cofactor function of FVIIIa variant R-HSA-9672396
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Diseases of hemostasis R-HSA-9671793
Metabolism of proteins R-HSA-392499
Defective F9 variant does not activate FX R-HSA-9673202
Diseases of hemostasis R-HSA-9671793
Defective factor IX causes hemophilia B R-HSA-9668250
Defective factor VIII causes hemophilia A R-HSA-9662001
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Hemostasis R-HSA-109582
Post-translational protein modification R-HSA-597592
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Common Pathway of Fibrin Clot Formation R-HSA-140875
Gamma-carboxylation of protein precursors R-HSA-159740
Metabolism of proteins R-HSA-392499
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective factor IX causes thrombophilia R-HSA-9672383
Disease R-HSA-1643685
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Defective F9 variant does not activate FX R-HSA-9673202
Defective cofactor function of FVIIIa variant R-HSA-9672396

Expression Atlas ENSG00000126218
LRG display in Ensembl gene LRG_548
NCBI gene (formerly Entrezgene) 2159
GeneCards 3528
HGNC Symbol HGNC:3528
MIM gene 613872
MIM morbid 227600
UniProtKB Gene Name Q5JVE8
WikiGene 2159