Gene: CASP8
Ensembl ID : ENSG00000064012
Description: caspase 8
Gene Synonyms: CASP-8,FLICE,MACH,MCH5
1 APIs:
132 Possible Orthologues:

CLEC7A/inflammasome pathway R-HSA-5660668
Diseases of programmed cell death R-HSA-9645723
NOD1/2 Signaling Pathway R-HSA-168638
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulation of necroptotic cell death R-HSA-5675482
TRAIL signaling R-HSA-75158
Programmed Cell Death R-HSA-5357801
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Cytokine Signaling in Immune system R-HSA-1280215
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signal Transduction R-HSA-162582
MyD88 cascade initiated on plasma membrane R-HSA-975871
Death Receptor Signaling R-HSA-73887
TRIF-mediated programmed cell death R-HSA-2562578
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TNF signaling R-HSA-75893
FasL/ CD95L signaling R-HSA-75157
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Disease R-HSA-1643685
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Regulated Necrosis R-HSA-5218859
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Signaling by Interleukins R-HSA-449147
Toll-like Receptor Cascades R-HSA-168898
RIPK1-mediated regulated necrosis R-HSA-5213460
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of TNFR1 signaling R-HSA-5357905
CASP8 activity is inhibited R-HSA-5218900
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TNFR1-induced proapoptotic signaling R-HSA-5357786
Dimerization of procaspase-8 R-HSA-69416
Apoptotic execution phase R-HSA-75153
Regulation of NF-kappa B signaling R-HSA-9758274
MyD88 dependent cascade initiated on endosome R-HSA-975155
CLEC7A (Dectin-1) signaling R-HSA-5607764
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-1 family signaling R-HSA-446652
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Innate Immune System R-HSA-168249
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Apoptotic cleavage of cellular proteins R-HSA-111465
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Immune System R-HSA-168256
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Interleukin-1 signaling R-HSA-9020702
C-type lectin receptors (CLRs) R-HSA-5621481
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation by c-FLIP R-HSA-3371378
Apoptosis R-HSA-109581
TRIF-mediated programmed cell death R-HSA-2562578
Regulation by c-FLIP R-HSA-3371378
Toll-like Receptor Cascades R-HSA-168898
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Regulation of TNFR1 signaling R-HSA-5357905
Diseases of programmed cell death R-HSA-9645723
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
CASP8 activity is inhibited R-HSA-5218900
CLEC7A/inflammasome pathway R-HSA-5660668
Death Receptor Signaling R-HSA-73887
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Immune System R-HSA-168256
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Apoptotic execution phase R-HSA-75153
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Cytokine Signaling in Immune system R-HSA-1280215
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Regulation of NF-kappa B signaling R-HSA-9758274
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
CLEC7A (Dectin-1) signaling R-HSA-5607764
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Interleukin-1 family signaling R-HSA-446652
Apoptotic cleavage of cellular proteins R-HSA-111465
NOD1/2 Signaling Pathway R-HSA-168638
Signal Transduction R-HSA-162582
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Interleukin-1 signaling R-HSA-9020702
TNFR1-induced proapoptotic signaling R-HSA-5357786
FasL/ CD95L signaling R-HSA-75157
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulated Necrosis R-HSA-5218859
Apoptosis R-HSA-109581
Signaling by Interleukins R-HSA-449147
Regulation of necroptotic cell death R-HSA-5675482
C-type lectin receptors (CLRs) R-HSA-5621481
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
RIPK1-mediated regulated necrosis R-HSA-5213460
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TNF signaling R-HSA-75893
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TRAIL signaling R-HSA-75158
Intrinsic Pathway for Apoptosis R-HSA-109606
Programmed Cell Death R-HSA-5357801
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 dependent cascade initiated on endosome R-HSA-975155
Dimerization of procaspase-8 R-HSA-69416
Disease R-HSA-1643685
FasL/ CD95L signaling R-HSA-75157
TNFR1-induced proapoptotic signaling R-HSA-5357786
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of TNFR1 signaling R-HSA-5357905
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Innate Immune System R-HSA-168249
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RIPK1-mediated regulated necrosis R-HSA-5213460
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TNF signaling R-HSA-75893
CLEC7A (Dectin-1) signaling R-HSA-5607764
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Death Receptor Signaling R-HSA-73887
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Regulation by c-FLIP R-HSA-3371378
Immune System R-HSA-168256
Diseases of programmed cell death R-HSA-9645723
Apoptotic execution phase R-HSA-75153
Regulation of NF-kappa B signaling R-HSA-9758274
Programmed Cell Death R-HSA-5357801
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
CASP8 activity is inhibited R-HSA-5218900
Apoptosis R-HSA-109581
TRIF-mediated programmed cell death R-HSA-2562578
CLEC7A/inflammasome pathway R-HSA-5660668
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Disease R-HSA-1643685
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAIL signaling R-HSA-75158
Regulated Necrosis R-HSA-5218859
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Interleukin-1 signaling R-HSA-9020702
Intrinsic Pathway for Apoptosis R-HSA-109606
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Apoptotic cleavage of cellular proteins R-HSA-111465
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Regulation of necroptotic cell death R-HSA-5675482
NOD1/2 Signaling Pathway R-HSA-168638
Dimerization of procaspase-8 R-HSA-69416
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-1 family signaling R-HSA-446652
CASP8 activity is inhibited R-HSA-5218900
CLEC7A (Dectin-1) signaling R-HSA-5607764
TRIF-mediated programmed cell death R-HSA-2562578
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Apoptotic cleavage of cellular proteins R-HSA-111465
TNFR1-induced proapoptotic signaling R-HSA-5357786
Programmed Cell Death R-HSA-5357801
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Regulation by c-FLIP R-HSA-3371378
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
C-type lectin receptors (CLRs) R-HSA-5621481
TRAIL signaling R-HSA-75158
Innate Immune System R-HSA-168249
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Diseases of programmed cell death R-HSA-9645723
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TNF signaling R-HSA-75893
Interleukin-1 family signaling R-HSA-446652
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Disease R-HSA-1643685
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Death Receptor Signaling R-HSA-73887
RIPK1-mediated regulated necrosis R-HSA-5213460
Apoptotic execution phase R-HSA-75153
Regulation of TNFR1 signaling R-HSA-5357905
MyD88 cascade initiated on plasma membrane R-HSA-975871
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Toll-like Receptor Cascades R-HSA-168898
Dimerization of procaspase-8 R-HSA-69416
NOD1/2 Signaling Pathway R-HSA-168638
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Regulation of NF-kappa B signaling R-HSA-9758274
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulated Necrosis R-HSA-5218859
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Regulation of necroptotic cell death R-HSA-5675482
MyD88-independent TLR4 cascade R-HSA-166166
FasL/ CD95L signaling R-HSA-75157
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
CLEC7A/inflammasome pathway R-HSA-5660668
Apoptosis R-HSA-109581
C-type lectin receptors (CLRs) R-HSA-5621481
Death Receptor Signaling R-HSA-73887
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TNFR1-induced proapoptotic signaling R-HSA-5357786
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
CLEC7A (Dectin-1) signaling R-HSA-5607764
MyD88 dependent cascade initiated on endosome R-HSA-975155
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Apoptotic cleavage of cellular proteins R-HSA-111465
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
RIPK1-mediated regulated necrosis R-HSA-5213460
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Immune System R-HSA-168256
Programmed Cell Death R-HSA-5357801
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
NOD1/2 Signaling Pathway R-HSA-168638
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Interleukin-1 family signaling R-HSA-446652
TNF signaling R-HSA-75893
Regulation by c-FLIP R-HSA-3371378
CLEC7A/inflammasome pathway R-HSA-5660668
MyD88-independent TLR4 cascade R-HSA-166166
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
CASP8 activity is inhibited R-HSA-5218900
Apoptotic execution phase R-HSA-75153
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Innate Immune System R-HSA-168249
Regulation of necroptotic cell death R-HSA-5675482
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Dimerization of procaspase-8 R-HSA-69416
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulated Necrosis R-HSA-5218859
Intrinsic Pathway for Apoptosis R-HSA-109606
Apoptosis R-HSA-109581
FasL/ CD95L signaling R-HSA-75157
TRAIL signaling R-HSA-75158
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll-like Receptor Cascades R-HSA-168898
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRIF-mediated programmed cell death R-HSA-2562578
Signaling by Interleukins R-HSA-449147
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Interleukin-1 signaling R-HSA-9020702
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Diseases of programmed cell death R-HSA-9645723
Regulation of TNFR1 signaling R-HSA-5357905
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Interleukins R-HSA-449147
CLEC7A/inflammasome pathway R-HSA-5660668
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of NF-kappa B signaling R-HSA-9758274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
TRIF-mediated programmed cell death R-HSA-2562578
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88 cascade initiated on plasma membrane R-HSA-975871
MyD88-independent TLR4 cascade R-HSA-166166
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Regulation by c-FLIP R-HSA-3371378
Signal Transduction R-HSA-162582
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
NOD1/2 Signaling Pathway R-HSA-168638
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
RIPK1-mediated regulated necrosis R-HSA-5213460
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TNF signaling R-HSA-75893
TNFR1-induced proapoptotic signaling R-HSA-5357786
MyD88 dependent cascade initiated on endosome R-HSA-975155
Disease R-HSA-1643685
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Apoptosis R-HSA-109581
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Toll-like Receptor Cascades R-HSA-168898
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Regulation of necroptotic cell death R-HSA-5675482
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Apoptotic execution phase R-HSA-75153
Programmed Cell Death R-HSA-5357801
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAIL signaling R-HSA-75158
FasL/ CD95L signaling R-HSA-75157
CASP8 activity is inhibited R-HSA-5218900
Innate Immune System R-HSA-168249
Dimerization of procaspase-8 R-HSA-69416
Death Receptor Signaling R-HSA-73887
Interleukin-1 signaling R-HSA-9020702
Diseases of programmed cell death R-HSA-9645723
Immune System R-HSA-168256
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Cytokine Signaling in Immune system R-HSA-1280215
Apoptotic cleavage of cellular proteins R-HSA-111465
Regulated Necrosis R-HSA-5218859
Intrinsic Pathway for Apoptosis R-HSA-109606
Interleukin-1 family signaling R-HSA-446652
C-type lectin receptors (CLRs) R-HSA-5621481
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
TNFR1-induced proapoptotic signaling R-HSA-5357786
MyD88-independent TLR4 cascade R-HSA-166166
Regulation by c-FLIP R-HSA-3371378
Regulated Necrosis R-HSA-5218859
FasL/ CD95L signaling R-HSA-75157
Death Receptor Signaling R-HSA-73887
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of NF-kappa B signaling R-HSA-9758274
Diseases of programmed cell death R-HSA-9645723
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Immune System R-HSA-168256
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Interleukin-1 family signaling R-HSA-446652
CASP8 activity is inhibited R-HSA-5218900
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Apoptosis R-HSA-109581
Regulation of necroptotic cell death R-HSA-5675482
Programmed Cell Death R-HSA-5357801
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Innate Immune System R-HSA-168249
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Apoptotic execution phase R-HSA-75153
NOD1/2 Signaling Pathway R-HSA-168638
TNF signaling R-HSA-75893
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
CLEC7A/inflammasome pathway R-HSA-5660668
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
RIPK1-mediated regulated necrosis R-HSA-5213460
Apoptotic cleavage of cellular proteins R-HSA-111465
MyD88 cascade initiated on plasma membrane R-HSA-975871
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
TRAIL signaling R-HSA-75158
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88 dependent cascade initiated on endosome R-HSA-975155
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by Interleukins R-HSA-449147
Dimerization of procaspase-8 R-HSA-69416
TRIF-mediated programmed cell death R-HSA-2562578
C-type lectin receptors (CLRs) R-HSA-5621481
Toll-like Receptor Cascades R-HSA-168898
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 dependent cascade initiated on endosome R-HSA-975155
Immune System R-HSA-168256
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRAIL signaling R-HSA-75158
CLEC7A (Dectin-1) signaling R-HSA-5607764
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Signal Transduction R-HSA-162582
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Innate Immune System R-HSA-168249
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
RIPK1-mediated regulated necrosis R-HSA-5213460
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Disease R-HSA-1643685
Regulated Necrosis R-HSA-5218859
TNFR1-induced proapoptotic signaling R-HSA-5357786
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Regulation of NF-kappa B signaling R-HSA-9758274
Apoptotic execution phase R-HSA-75153
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Dimerization of procaspase-8 R-HSA-69416
Regulation of necroptotic cell death R-HSA-5675482
Regulation of TNFR1 signaling R-HSA-5357905
Interleukin-1 signaling R-HSA-9020702
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
C-type lectin receptors (CLRs) R-HSA-5621481
TNF signaling R-HSA-75893
Regulation by c-FLIP R-HSA-3371378
Toll-like Receptor Cascades R-HSA-168898
FasL/ CD95L signaling R-HSA-75157
NOD1/2 Signaling Pathway R-HSA-168638
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
CASP8 activity is inhibited R-HSA-5218900
Apoptosis R-HSA-109581
Intrinsic Pathway for Apoptosis R-HSA-109606
CLEC7A/inflammasome pathway R-HSA-5660668
Death Receptor Signaling R-HSA-73887
Apoptotic cleavage of cellular proteins R-HSA-111465
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Diseases of programmed cell death R-HSA-9645723
Interleukin-1 family signaling R-HSA-446652
TRIF-mediated programmed cell death R-HSA-2562578
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Programmed Cell Death R-HSA-5357801
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulated Necrosis R-HSA-5218859
Dimerization of procaspase-8 R-HSA-69416
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Toll-like Receptor Cascades R-HSA-168898
FasL/ CD95L signaling R-HSA-75157
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of TNFR1 signaling R-HSA-5357905
Disease R-HSA-1643685
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
TNF signaling R-HSA-75893
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signal Transduction R-HSA-162582
MyD88-independent TLR4 cascade R-HSA-166166
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRIF-mediated programmed cell death R-HSA-2562578
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Regulation of NF-kappa B signaling R-HSA-9758274
CASP8 activity is inhibited R-HSA-5218900
NOD1/2 Signaling Pathway R-HSA-168638
Death Receptor Signaling R-HSA-73887
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Regulation by c-FLIP R-HSA-3371378
TRAIL signaling R-HSA-75158
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 cascade initiated on plasma membrane R-HSA-975871
Apoptotic cleavage of cellular proteins R-HSA-111465
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by Interleukins R-HSA-449147
Intrinsic Pathway for Apoptosis R-HSA-109606
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Programmed Cell Death R-HSA-5357801
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Apoptotic execution phase R-HSA-75153
RIPK1-mediated regulated necrosis R-HSA-5213460
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Apoptosis R-HSA-109581
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Regulation of necroptotic cell death R-HSA-5675482
CLEC7A (Dectin-1) signaling R-HSA-5607764
Interleukin-1 signaling R-HSA-9020702
CLEC7A/inflammasome pathway R-HSA-5660668
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Diseases of programmed cell death R-HSA-9645723
TNFR1-induced proapoptotic signaling R-HSA-5357786
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation by c-FLIP R-HSA-3371378
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Dimerization of procaspase-8 R-HSA-69416
Diseases of programmed cell death R-HSA-9645723
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
C-type lectin receptors (CLRs) R-HSA-5621481
Regulated Necrosis R-HSA-5218859
Interleukin-1 family signaling R-HSA-446652
Programmed Cell Death R-HSA-5357801
Death Receptor Signaling R-HSA-73887
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
RIPK1-mediated regulated necrosis R-HSA-5213460
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Interleukins R-HSA-449147
Apoptotic execution phase R-HSA-75153
Cytokine Signaling in Immune system R-HSA-1280215
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
NOD1/2 Signaling Pathway R-HSA-168638
Apoptotic cleavage of cellular proteins R-HSA-111465
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRAIL signaling R-HSA-75158
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Interleukin-1 signaling R-HSA-9020702
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Immune System R-HSA-168256
CASP8 activity is inhibited R-HSA-5218900
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
FasL/ CD95L signaling R-HSA-75157
CLEC7A/inflammasome pathway R-HSA-5660668
TNFR1-induced proapoptotic signaling R-HSA-5357786
Disease R-HSA-1643685
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRIF-mediated programmed cell death R-HSA-2562578
TNF signaling R-HSA-75893
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
CLEC7A (Dectin-1) signaling R-HSA-5607764
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Regulation of NF-kappa B signaling R-HSA-9758274
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
MyD88-independent TLR4 cascade R-HSA-166166
Regulation of necroptotic cell death R-HSA-5675482
Apoptosis R-HSA-109581
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061

Expression Atlas ENSG00000064012
LRG display in Ensembl gene LRG_34
NCBI gene (formerly Entrezgene) 841
GeneCards 1509
HGNC Symbol HGNC:1509
MIM gene 601763
MIM morbid 607271
UniProtKB Gene Name Q14790
WikiGene 841
Gene: CTSS
Ensembl ID : ENSG00000163131
Description: cathepsin S
Gene Synonyms:
1 APIs:
270 Possible Orthologues:

Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
Endosomal/Vacuolar pathway R-HSA-1236977
Neutrophil degranulation R-HSA-6798695
Degradation of the extracellular matrix R-HSA-1474228
Immune System R-HSA-168256
Collagen formation R-HSA-1474290
MHC class II antigen presentation R-HSA-2132295
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Trafficking and processing of endosomal TLR R-HSA-1679131
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Trafficking and processing of endosomal TLR R-HSA-1679131
Toll-like Receptor Cascades R-HSA-168898
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
Extracellular matrix organization R-HSA-1474244
Adaptive Immune System R-HSA-1280218
Endosomal/Vacuolar pathway R-HSA-1236977
Immune System R-HSA-168256
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Collagen formation R-HSA-1474290
MHC class II antigen presentation R-HSA-2132295
Degradation of the extracellular matrix R-HSA-1474228
MHC class II antigen presentation R-HSA-2132295
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Degradation of the extracellular matrix R-HSA-1474228
Toll-like Receptor Cascades R-HSA-168898
Class I MHC mediated antigen processing & presentation R-HSA-983169
Collagen formation R-HSA-1474290
Endosomal/Vacuolar pathway R-HSA-1236977
Adaptive Immune System R-HSA-1280218
Trafficking and processing of endosomal TLR R-HSA-1679131
Immune System R-HSA-168256
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Antigen processing-Cross presentation R-HSA-1236975
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Collagen formation R-HSA-1474290
Extracellular matrix organization R-HSA-1474244
Trafficking and processing of endosomal TLR R-HSA-1679131
Endosomal/Vacuolar pathway R-HSA-1236977
MHC class II antigen presentation R-HSA-2132295
Antigen processing-Cross presentation R-HSA-1236975
Class I MHC mediated antigen processing & presentation R-HSA-983169
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Toll-like Receptor Cascades R-HSA-168898
Adaptive Immune System R-HSA-1280218
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Toll-like Receptor Cascades R-HSA-168898
Extracellular matrix organization R-HSA-1474244
Collagen formation R-HSA-1474290
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Trafficking and processing of endosomal TLR R-HSA-1679131
MHC class II antigen presentation R-HSA-2132295
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Class I MHC mediated antigen processing & presentation R-HSA-983169
Endosomal/Vacuolar pathway R-HSA-1236977
Antigen processing-Cross presentation R-HSA-1236975
Endosomal/Vacuolar pathway R-HSA-1236977
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neutrophil degranulation R-HSA-6798695
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Innate Immune System R-HSA-168249
Collagen formation R-HSA-1474290
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Adaptive Immune System R-HSA-1280218
Trafficking and processing of endosomal TLR R-HSA-1679131
MHC class II antigen presentation R-HSA-2132295
Degradation of the extracellular matrix R-HSA-1474228
Toll-like Receptor Cascades R-HSA-168898
MHC class II antigen presentation R-HSA-2132295
Class I MHC mediated antigen processing & presentation R-HSA-983169
Endosomal/Vacuolar pathway R-HSA-1236977
Adaptive Immune System R-HSA-1280218
Collagen formation R-HSA-1474290
Toll-like Receptor Cascades R-HSA-168898
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Extracellular matrix organization R-HSA-1474244
Neutrophil degranulation R-HSA-6798695
Trafficking and processing of endosomal TLR R-HSA-1679131
Degradation of the extracellular matrix R-HSA-1474228
Collagen formation R-HSA-1474290
Trafficking and processing of endosomal TLR R-HSA-1679131
Class I MHC mediated antigen processing & presentation R-HSA-983169
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Endosomal/Vacuolar pathway R-HSA-1236977
Innate Immune System R-HSA-168249
MHC class II antigen presentation R-HSA-2132295
Antigen processing-Cross presentation R-HSA-1236975
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Degradation of the extracellular matrix R-HSA-1474228
Adaptive Immune System R-HSA-1280218
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Degradation of the extracellular matrix R-HSA-1474228
Adaptive Immune System R-HSA-1280218
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Collagen formation R-HSA-1474290
MHC class II antigen presentation R-HSA-2132295
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Endosomal/Vacuolar pathway R-HSA-1236977
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Trafficking and processing of endosomal TLR R-HSA-1679131
Class I MHC mediated antigen processing & presentation R-HSA-983169
Trafficking and processing of endosomal TLR R-HSA-1679131
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
Innate Immune System R-HSA-168249
MHC class II antigen presentation R-HSA-2132295
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Degradation of the extracellular matrix R-HSA-1474228
Endosomal/Vacuolar pathway R-HSA-1236977
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090
Adaptive Immune System R-HSA-1280218
Collagen formation R-HSA-1474290

Expression Atlas ENSG00000163131
NCBI gene (formerly Entrezgene) 1520
GeneCards 2545
HGNC Symbol HGNC:2545
MIM gene 116845
UniProtKB Gene Name U3KQE7
WikiGene 1520
Gene: PSMB8
Ensembl ID : ENSG00000204264
Description: proteasome 20S subunit beta 8
Gene Synonyms: BETA5I,D6S216E,LMP7,PSMB5I,RING10
6 APIs:
221 Possible Orthologues:

Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Synthesis of DNA R-HSA-69239
Ub-specific processing proteases R-HSA-5689880
ABC transporter disorders R-HSA-5619084
Post-translational protein modification R-HSA-597592
ABC-family proteins mediated transport R-HSA-382556
Programmed Cell Death R-HSA-5357801
FCERI mediated NF-kB activation R-HSA-2871837
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nervous system development R-HSA-9675108
Switching of origins to a post-replicative state R-HSA-69052
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of beta-catenin by the destruction complex R-HSA-195253
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Interleukin-1 family signaling R-HSA-446652
Regulation of Apoptosis R-HSA-169911
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK family signaling cascades R-HSA-5683057
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism of amino acids and derivatives R-HSA-71291
MAPK1/MAPK3 signaling R-HSA-5684996
S Phase R-HSA-69242
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hedgehog ligand biogenesis R-HSA-5358346
Developmental Biology R-HSA-1266738
Orc1 removal from chromatin R-HSA-68949
Stabilization of p53 R-HSA-69541
Metabolism R-HSA-1430728
Hedgehog 'on' state R-HSA-5632684
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle R-HSA-1640170
Cytokine Signaling in Immune system R-HSA-1280215
PTEN Regulation R-HSA-6807070
RAF/MAP kinase cascade R-HSA-5673001
HIV Infection R-HSA-162906
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 signaling R-HSA-9020702
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX3 R-HSA-8878159
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular response to chemical stress R-HSA-9711123
Regulation of RAS by GAPs R-HSA-5658442
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI1 by the proteasome R-HSA-5610780
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by WNT R-HSA-195721
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Immune System R-HSA-168256
Beta-catenin independent WNT signaling R-HSA-3858494
G1/S Transition R-HSA-69206
Degradation of DVL R-HSA-4641258
Metabolism of proteins R-HSA-392499
Mitotic G1 phase and G1/S transition R-HSA-453279
ER-Phagosome pathway R-HSA-1236974
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Intracellular signaling by second messengers R-HSA-9006925
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
Infectious disease R-HSA-5663205
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing-Cross presentation R-HSA-1236975
Signaling by Interleukins R-HSA-449147
Interferon alpha/beta signaling R-HSA-909733
PIP3 activates AKT signaling R-HSA-1257604
UCH proteinases R-HSA-5689603
Cell Cycle Checkpoints R-HSA-69620
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Disorders of transmembrane transporters R-HSA-5619115
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Apoptosis R-HSA-109581
Vpu mediated degradation of CD4 R-HSA-180534
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of polyamines R-HSA-351202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle, Mitotic R-HSA-69278
Signal Transduction R-HSA-162582
Negative regulation of NOTCH4 signaling R-HSA-9604323
Neddylation R-HSA-8951664
DNA Replication R-HSA-69306
TCR signaling R-HSA-202403
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Independent DNA Damage Response R-HSA-69610
Interferon Signaling R-HSA-913531
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular responses to stimuli R-HSA-8953897
Signaling by Hedgehog R-HSA-5358351
Metabolism of RNA R-HSA-8953854
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Host Interactions of HIV factors R-HSA-162909
Separation of Sister Chromatids R-HSA-2467813
Adaptive Immune System R-HSA-1280218
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX2 expression and activity R-HSA-8939902
PCP/CE pathway R-HSA-4086400
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transport of small molecules R-HSA-382551
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Assembly of the pre-replicative complex R-HSA-68867
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic G2-G2/M phases R-HSA-453274
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Defective CFTR causes cystic fibrosis R-HSA-5678895
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Innate Immune System R-HSA-168249
Deubiquitination R-HSA-5688426
Disease R-HSA-1643685
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of PTEN stability and activity R-HSA-8948751
M Phase R-HSA-68886
Degradation of AXIN R-HSA-4641257
Signaling by ROBO receptors R-HSA-376176
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Anaphase R-HSA-68882
Downstream TCR signaling R-HSA-202424
Hh mutants abrogate ligand secretion R-HSA-5387390
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX3 expression and activity R-HSA-8941858
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX1 R-HSA-8878171
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism R-HSA-1430728
Interleukin-1 signaling R-HSA-9020702
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI1 by the proteasome R-HSA-5610780
Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Apoptosis R-HSA-109581
Post-translational protein modification R-HSA-597592
Metabolism of RNA R-HSA-8953854
Vpu mediated degradation of CD4 R-HSA-180534
Neddylation R-HSA-8951664
Metabolism of amino acids and derivatives R-HSA-71291
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to chemical stress R-HSA-9711123
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Hedgehog R-HSA-5358351
G2/M Transition R-HSA-69275
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog ligand biogenesis R-HSA-5358346
Interferon Signaling R-HSA-913531
Generic Transcription Pathway R-HSA-212436
Interferon alpha/beta signaling R-HSA-909733
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Asymmetric localization of PCP proteins R-HSA-4608870
HIV Infection R-HSA-162906
Signaling by WNT R-HSA-195721
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by NOTCH4 R-HSA-9013694
ABC-family proteins mediated transport R-HSA-382556
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic Anaphase R-HSA-68882
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
Regulation of PTEN stability and activity R-HSA-8948751
S Phase R-HSA-69242
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
Class I MHC mediated antigen processing & presentation R-HSA-983169
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by ROBO receptors R-HSA-376176
Intracellular signaling by second messengers R-HSA-9006925
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of Apoptosis R-HSA-169911
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FCERI mediated NF-kB activation R-HSA-2871837
Assembly of the pre-replicative complex R-HSA-68867
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK1/MAPK3 signaling R-HSA-5684996
Developmental Biology R-HSA-1266738
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TCR signaling R-HSA-202403
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
PIP3 activates AKT signaling R-HSA-1257604
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
UCH proteinases R-HSA-5689603
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'on' state R-HSA-5632684
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G2/M Checkpoints R-HSA-69481
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S Transition R-HSA-69206
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Deubiquitination R-HSA-5688426
Infectious disease R-HSA-5663205
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Regulation of RUNX3 expression and activity R-HSA-8941858
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by NOTCH R-HSA-157118
Separation of Sister Chromatids R-HSA-2467813
p53-Independent DNA Damage Response R-HSA-69610
Ub-specific processing proteases R-HSA-5689880
Degradation of DVL R-HSA-4641258
Axon guidance R-HSA-422475
Cellular response to hypoxia R-HSA-1234174
PCP/CE pathway R-HSA-4086400
Hh mutants are degraded by ERAD R-HSA-5362768
C-type lectin receptors (CLRs) R-HSA-5621481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Synthesis of DNA R-HSA-69239
PTEN Regulation R-HSA-6807070
RNA Polymerase II Transcription R-HSA-73857
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing-Cross presentation R-HSA-1236975
Innate Immune System R-HSA-168249
Cellular responses to stimuli R-HSA-8953897
Regulation of RAS by GAPs R-HSA-5658442
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
ABC transporter disorders R-HSA-5619084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
Programmed Cell Death R-HSA-5357801
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Nuclear events mediated by NFE2L2 R-HSA-9759194
ER-Phagosome pathway R-HSA-1236974
p53-Dependent G1 DNA Damage Response R-HSA-69563
Immune System R-HSA-168256
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
Transport of small molecules R-HSA-382551
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'off' state R-HSA-5610787
Beta-catenin independent WNT signaling R-HSA-3858494
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle, Mitotic R-HSA-69278
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
Downstream TCR signaling R-HSA-202424
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hh mutants are degraded by ERAD R-HSA-5362768
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Gene expression (Transcription) R-HSA-74160
Apoptosis R-HSA-109581
Regulation of RUNX2 expression and activity R-HSA-8939902
DNA Replication R-HSA-69306
Signaling by NOTCH4 R-HSA-9013694
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PIP3 activates AKT signaling R-HSA-1257604
G2/M Transition R-HSA-69275
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Disorders of transmembrane transporters R-HSA-5619115
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ub-specific processing proteases R-HSA-5689880
Regulation of Apoptosis R-HSA-169911
UCH proteinases R-HSA-5689603
Transport of small molecules R-HSA-382551
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Synthesis of DNA R-HSA-69239
Activation of NF-kappaB in B cells R-HSA-1169091
Assembly of the pre-replicative complex R-HSA-68867
Infectious disease R-HSA-5663205
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Host Interactions of HIV factors R-HSA-162909
ABC transporter disorders R-HSA-5619084
Interferon alpha/beta signaling R-HSA-909733
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Orc1 removal from chromatin R-HSA-68949
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interferon Signaling R-HSA-913531
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Anaphase R-HSA-68882
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stimuli R-HSA-8953897
Metabolism of proteins R-HSA-392499
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of NOTCH4 signaling R-HSA-9604323
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
DNA Replication Pre-Initiation R-HSA-69002
G1/S Transition R-HSA-69206
Developmental Biology R-HSA-1266738
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by ROBO receptors R-HSA-376176
S Phase R-HSA-69242
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX2 R-HSA-8878166
FCERI mediated NF-kB activation R-HSA-2871837
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
p53-Independent DNA Damage Response R-HSA-69610
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Checkpoints R-HSA-69481
ABC-family proteins mediated transport R-HSA-382556
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Mitotic G1 phase and G1/S transition R-HSA-453279
TCR signaling R-HSA-202403
Hedgehog 'on' state R-HSA-5632684
ER-Phagosome pathway R-HSA-1236974
MAPK family signaling cascades R-HSA-5683057
TCF dependent signaling in response to WNT R-HSA-201681
Switching of origins to a post-replicative state R-HSA-69052
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cell Cycle R-HSA-1640170
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Metabolism of polyamines R-HSA-351202
Stabilization of p53 R-HSA-69541
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of amino acids and derivatives R-HSA-71291
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by WNT R-HSA-195721
Interleukin-1 family signaling R-HSA-446652
Cell Cycle, Mitotic R-HSA-69278
Nervous system development R-HSA-9675108
Mitotic Metaphase and Anaphase R-HSA-2555396
Hedgehog ligand biogenesis R-HSA-5358346
Immune System R-HSA-168256
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PTEN Regulation R-HSA-6807070
M Phase R-HSA-68886
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
Degradation of DVL R-HSA-4641258
Mitotic G2-G2/M phases R-HSA-453274
Interleukin-1 signaling R-HSA-9020702
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RAS by GAPs R-HSA-5658442
Programmed Cell Death R-HSA-5357801
Cyclin E associated events during G1/S transition R-HSA-69202
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism R-HSA-1430728
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH R-HSA-157118
Post-translational protein modification R-HSA-597592
Downstream TCR signaling R-HSA-202424
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
MAPK1/MAPK3 signaling R-HSA-5684996
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'off' state R-HSA-5610787
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Antigen processing-Cross presentation R-HSA-1236975
Regulation of PTEN stability and activity R-HSA-8948751
Nuclear events mediated by NFE2L2 R-HSA-9759194
Adaptive Immune System R-HSA-1280218
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
Defective CFTR causes cystic fibrosis R-HSA-5678895
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of RUNX3 expression and activity R-HSA-8941858
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by Hedgehog R-HSA-5358351
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
ER-Phagosome pathway R-HSA-1236974
Regulation of mitotic cell cycle R-HSA-453276
HIV Infection R-HSA-162906
Hedgehog ligand biogenesis R-HSA-5358346
Interferon alpha/beta signaling R-HSA-909733
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of RUNX3 expression and activity R-HSA-8941858
G2/M Transition R-HSA-69275
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing-Cross presentation R-HSA-1236975
G1/S Transition R-HSA-69206
DNA Replication R-HSA-69306
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Disorders of transmembrane transporters R-HSA-5619115
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular response to chemical stress R-HSA-9711123
Cell Cycle Checkpoints R-HSA-69620
Generic Transcription Pathway R-HSA-212436
Regulation of Apoptosis R-HSA-169911
Orc1 removal from chromatin R-HSA-68949
Signaling by Interleukins R-HSA-449147
Metabolism R-HSA-1430728
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Host Interactions of HIV factors R-HSA-162909
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
M Phase R-HSA-68886
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TCF dependent signaling in response to WNT R-HSA-201681
Synthesis of DNA R-HSA-69239
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Deubiquitination R-HSA-5688426
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PCP/CE pathway R-HSA-4086400
Mitotic Anaphase R-HSA-68882
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Axon guidance R-HSA-422475
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX1 R-HSA-8878171
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Hedgehog 'on' state R-HSA-5632684
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of RNA R-HSA-8953854
Signaling by NOTCH R-HSA-157118
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic G1 phase and G1/S transition R-HSA-453279
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Dependent G1 DNA Damage Response R-HSA-69563
RAF/MAP kinase cascade R-HSA-5673001
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Interleukin-1 signaling R-HSA-9020702
Switching of origins to a post-replicative state R-HSA-69052
Infectious disease R-HSA-5663205
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neddylation R-HSA-8951664
Mitotic G2-G2/M phases R-HSA-453274
Post-translational protein modification R-HSA-597592
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PTEN Regulation R-HSA-6807070
Signaling by NOTCH4 R-HSA-9013694
Metabolism of amino acids and derivatives R-HSA-71291
Gene expression (Transcription) R-HSA-74160
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX2 R-HSA-8878166
Developmental Biology R-HSA-1266738
MAPK family signaling cascades R-HSA-5683057
Degradation of DVL R-HSA-4641258
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Separation of Sister Chromatids R-HSA-2467813
Cellular responses to stress R-HSA-2262752
Degradation of GLI2 by the proteasome R-HSA-5610783
Interleukin-1 family signaling R-HSA-446652
RNA Polymerase II Transcription R-HSA-73857
TCR signaling R-HSA-202403
Metabolism of polyamines R-HSA-351202
Programmed Cell Death R-HSA-5357801
Cellular response to hypoxia R-HSA-1234174
Apoptosis R-HSA-109581
Defective CFTR causes cystic fibrosis R-HSA-5678895
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of PTEN stability and activity R-HSA-8948751
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Hh mutants abrogate ligand secretion R-HSA-5387390
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication Pre-Initiation R-HSA-69002
ABC transporter disorders R-HSA-5619084
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'off' state R-HSA-5610787
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interferon Signaling R-HSA-913531
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Downstream TCR signaling R-HSA-202424
C-type lectin receptors (CLRs) R-HSA-5621481
Stabilization of p53 R-HSA-69541
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
ABC-family proteins mediated transport R-HSA-382556
Immune System R-HSA-168256
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
Degradation of GLI1 by the proteasome R-HSA-5610780
Transport of small molecules R-HSA-382551
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of RAS by GAPs R-HSA-5658442
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
UCH proteinases R-HSA-5689603
Negative regulation of NOTCH4 signaling R-HSA-9604323
S Phase R-HSA-69242
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by WNT R-HSA-195721
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Innate Immune System R-HSA-168249
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M Checkpoints R-HSA-69481
Disorders of transmembrane transporters R-HSA-5619115
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Separation of Sister Chromatids R-HSA-2467813
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of polyamines R-HSA-351202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hh mutants are degraded by ERAD R-HSA-5362768
DNA Replication Pre-Initiation R-HSA-69002
Cytokine Signaling in Immune system R-HSA-1280215
MAPK6/MAPK4 signaling R-HSA-5687128
Interferon alpha/beta signaling R-HSA-909733
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Orc1 removal from chromatin R-HSA-68949
Mitotic Metaphase and Anaphase R-HSA-2555396
Transcriptional regulation by RUNX3 R-HSA-8878159
Post-translational protein modification R-HSA-597592
DNA Replication R-HSA-69306
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S Transition R-HSA-69206
Mitotic Anaphase R-HSA-68882
NIK-->noncanonical NF-kB signaling R-HSA-5676590
RAF/MAP kinase cascade R-HSA-5673001
Ub-specific processing proteases R-HSA-5689880
Regulation of RAS by GAPs R-HSA-5658442
Asymmetric localization of PCP proteins R-HSA-4608870
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Assembly of the pre-replicative complex R-HSA-68867
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
S Phase R-HSA-69242
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
UCH proteinases R-HSA-5689603
CLEC7A (Dectin-1) signaling R-HSA-5607764
Stabilization of p53 R-HSA-69541
Transport of small molecules R-HSA-382551
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PTEN Regulation R-HSA-6807070
Signaling by WNT R-HSA-195721
Regulation of PTEN stability and activity R-HSA-8948751
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC-family proteins mediated transport R-HSA-382556
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
HIV Infection R-HSA-162906
Programmed Cell Death R-HSA-5357801
Metabolism of proteins R-HSA-392499
Class I MHC mediated antigen processing & presentation R-HSA-983169
PIP3 activates AKT signaling R-HSA-1257604
Axon guidance R-HSA-422475
Regulation of RUNX3 expression and activity R-HSA-8941858
Generic Transcription Pathway R-HSA-212436
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Signaling by Interleukins R-HSA-449147
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'off' state R-HSA-5610787
Metabolism R-HSA-1430728
ABC transporter disorders R-HSA-5619084
Cellular responses to stress R-HSA-2262752
Nuclear events mediated by NFE2L2 R-HSA-9759194
ER-Phagosome pathway R-HSA-1236974
TCR signaling R-HSA-202403
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle R-HSA-1640170
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
MAPK family signaling cascades R-HSA-5683057
p53-Dependent G1 DNA Damage Response R-HSA-69563
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of amino acids and derivatives R-HSA-71291
p53-Independent DNA Damage Response R-HSA-69610
Host Interactions of HIV factors R-HSA-162909
Vif-mediated degradation of APOBEC3G R-HSA-180585
Downstream TCR signaling R-HSA-202424
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog 'on' state R-HSA-5632684
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Synthesis of DNA R-HSA-69239
Signaling by NOTCH4 R-HSA-9013694
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
M Phase R-HSA-68886
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by ROBO receptors R-HSA-376176
Switching of origins to a post-replicative state R-HSA-69052
MAPK1/MAPK3 signaling R-HSA-5684996
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX1 R-HSA-8878171
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stimuli R-HSA-8953897
Interleukin-1 signaling R-HSA-9020702
Negative regulation of NOTCH4 signaling R-HSA-9604323
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 family signaling R-HSA-446652
PCP/CE pathway R-HSA-4086400
Transcriptional regulation by RUNX2 R-HSA-8878166
Nervous system development R-HSA-9675108
Interferon Signaling R-HSA-913531
Degradation of GLI1 by the proteasome R-HSA-5610780
Mitotic G1 phase and G1/S transition R-HSA-453279
Apoptosis R-HSA-109581
Beta-catenin independent WNT signaling R-HSA-3858494
Cyclin E associated events during G1/S transition R-HSA-69202
Neddylation R-HSA-8951664
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic G2-G2/M phases R-HSA-453274
Developmental Biology R-HSA-1266738
Degradation of GLI2 by the proteasome R-HSA-5610783
Signal Transduction R-HSA-162582
Cell Cycle Checkpoints R-HSA-69620
Deubiquitination R-HSA-5688426
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of AXIN R-HSA-4641257
Cellular response to hypoxia R-HSA-1234174
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G2/M Transition R-HSA-69275
G2/M Checkpoints R-HSA-69481
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
Vpu mediated degradation of CD4 R-HSA-180534
Antigen processing-Cross presentation R-HSA-1236975
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G2/M Checkpoints R-HSA-69481
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RAS by GAPs R-HSA-5658442
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX3 expression and activity R-HSA-8941858
Programmed Cell Death R-HSA-5357801
Innate Immune System R-HSA-168249
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH R-HSA-157118
Apoptosis R-HSA-109581
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Generic Transcription Pathway R-HSA-212436
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
Immune System R-HSA-168256
Signaling by WNT R-HSA-195721
Infectious disease R-HSA-5663205
Degradation of DVL R-HSA-4641258
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Neddylation R-HSA-8951664
Assembly of the pre-replicative complex R-HSA-68867
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of AXIN R-HSA-4641257
Interferon Signaling R-HSA-913531
Activation of NF-kappaB in B cells R-HSA-1169091
Antigen processing-Cross presentation R-HSA-1236975
Interferon alpha/beta signaling R-HSA-909733
Signaling by Hedgehog R-HSA-5358351
Switching of origins to a post-replicative state R-HSA-69052
Disorders of transmembrane transporters R-HSA-5619115
G2/M Transition R-HSA-69275
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mitotic cell cycle R-HSA-453276
RAF/MAP kinase cascade R-HSA-5673001
C-type lectin receptors (CLRs) R-HSA-5621481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Adaptive Immune System R-HSA-1280218
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI2 by the proteasome R-HSA-5610783
Vpu mediated degradation of CD4 R-HSA-180534
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of Apoptosis R-HSA-169911
Developmental Biology R-HSA-1266738
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle R-HSA-1640170
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Nervous system development R-HSA-9675108
Cellular responses to stress R-HSA-2262752
PCP/CE pathway R-HSA-4086400
Cytokine Signaling in Immune system R-HSA-1280215
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Axon guidance R-HSA-422475
M Phase R-HSA-68886
Degradation of beta-catenin by the destruction complex R-HSA-195253
Defective CFTR causes cystic fibrosis R-HSA-5678895
ER-Phagosome pathway R-HSA-1236974
Metabolism R-HSA-1430728
Metabolism of polyamines R-HSA-351202
Signaling by ROBO receptors R-HSA-376176
G1/S DNA Damage Checkpoints R-HSA-69615
Synthesis of DNA R-HSA-69239
TCR signaling R-HSA-202403
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to hypoxia R-HSA-1234174
Intracellular signaling by second messengers R-HSA-9006925
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle Checkpoints R-HSA-69620
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK1/MAPK3 signaling R-HSA-5684996
Post-translational protein modification R-HSA-597592
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
ABC transporter disorders R-HSA-5619084
G1/S Transition R-HSA-69206
Metabolism of proteins R-HSA-392499
Hh mutants are degraded by ERAD R-HSA-5362768
DNA Replication Pre-Initiation R-HSA-69002
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RNA Polymerase II Transcription R-HSA-73857
Signaling by Interleukins R-HSA-449147
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX3 R-HSA-8878159
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
PTEN Regulation R-HSA-6807070
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
HIV Infection R-HSA-162906
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent DNA Damage Response R-HSA-69610
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'on' state R-HSA-5632684
Signaling by NOTCH4 R-HSA-9013694
PIP3 activates AKT signaling R-HSA-1257604
Deubiquitination R-HSA-5688426
Hedgehog ligand biogenesis R-HSA-5358346
S Phase R-HSA-69242
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK family signaling cascades R-HSA-5683057
TCF dependent signaling in response to WNT R-HSA-201681
UCH proteinases R-HSA-5689603
Interleukin-1 family signaling R-HSA-446652
Mitotic G1 phase and G1/S transition R-HSA-453279
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'off' state R-HSA-5610787
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
ABC-family proteins mediated transport R-HSA-382556
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Class I MHC mediated antigen processing & presentation R-HSA-983169
Ub-specific processing proteases R-HSA-5689880
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Stabilization of p53 R-HSA-69541
Interferon Signaling R-HSA-913531
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX3 R-HSA-8878159
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCR signaling R-HSA-202403
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interferon alpha/beta signaling R-HSA-909733
PTEN Regulation R-HSA-6807070
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
C-type lectin receptors (CLRs) R-HSA-5621481
G1/S Transition R-HSA-69206
Stabilization of p53 R-HSA-69541
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Generic Transcription Pathway R-HSA-212436
Interleukin-1 signaling R-HSA-9020702
Infectious disease R-HSA-5663205
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Signaling by Interleukins R-HSA-449147
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Deubiquitination R-HSA-5688426
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of expression of SLITs and ROBOs R-HSA-9010553
HIV Infection R-HSA-162906
Axon guidance R-HSA-422475
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
DNA Replication Pre-Initiation R-HSA-69002
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle, Mitotic R-HSA-69278
Cellular response to chemical stress R-HSA-9711123
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Assembly of the pre-replicative complex R-HSA-68867
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
Regulation of Apoptosis R-HSA-169911
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Asymmetric localization of PCP proteins R-HSA-4608870
PCP/CE pathway R-HSA-4086400
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic G1 phase and G1/S transition R-HSA-453279
Switching of origins to a post-replicative state R-HSA-69052
Neddylation R-HSA-8951664
Hedgehog 'on' state R-HSA-5632684
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream TCR signaling R-HSA-202424
Synthesis of DNA R-HSA-69239
Cyclin E associated events during G1/S transition R-HSA-69202
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Separation of Sister Chromatids R-HSA-2467813
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of GLI2 by the proteasome R-HSA-5610783
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
KEAP1-NFE2L2 pathway R-HSA-9755511
Intracellular signaling by second messengers R-HSA-9006925
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
DNA Replication R-HSA-69306
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G2/M Transition R-HSA-69275
Interleukin-1 family signaling R-HSA-446652
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC transporter disorders R-HSA-5619084
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cytokine Signaling in Immune system R-HSA-1280215
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PIP3 activates AKT signaling R-HSA-1257604
Class I MHC mediated antigen processing & presentation R-HSA-983169
Transport of small molecules R-HSA-382551
Metabolism of proteins R-HSA-392499
p53-Independent DNA Damage Response R-HSA-69610
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
UCH proteinases R-HSA-5689603
ER-Phagosome pathway R-HSA-1236974
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of polyamines R-HSA-351202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of RAS by GAPs R-HSA-5658442
TCF dependent signaling in response to WNT R-HSA-201681
Transcriptional regulation by RUNX2 R-HSA-8878166
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nervous system development R-HSA-9675108
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of NF-kappaB in B cells R-HSA-1169091
Post-translational protein modification R-HSA-597592
Cellular responses to stimuli R-HSA-8953897
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'off' state R-HSA-5610787
Beta-catenin independent WNT signaling R-HSA-3858494
Programmed Cell Death R-HSA-5357801
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of RNA R-HSA-8953854
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ub-specific processing proteases R-HSA-5689880
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Infectious disease R-HSA-5663205
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of proteins R-HSA-392499
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic Metaphase and Anaphase R-HSA-2555396
Stabilization of p53 R-HSA-69541
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'on' state R-HSA-5632684
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK family signaling cascades R-HSA-5683057
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular response to chemical stress R-HSA-9711123
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 signaling R-HSA-9020702
Neddylation R-HSA-8951664
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
Disorders of transmembrane transporters R-HSA-5619115
Signal Transduction R-HSA-162582
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
UCH proteinases R-HSA-5689603
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of beta-catenin by the destruction complex R-HSA-195253
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of AXIN R-HSA-4641257
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI1 by the proteasome R-HSA-5610780
PIP3 activates AKT signaling R-HSA-1257604
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Host Interactions of HIV factors R-HSA-162909
Cell Cycle, Mitotic R-HSA-69278
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Interleukins R-HSA-449147
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stimuli R-HSA-8953897
Signaling by WNT R-HSA-195721
Apoptosis R-HSA-109581
Interferon Signaling R-HSA-913531
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants are degraded by ERAD R-HSA-5362768
HIV Infection R-HSA-162906
Post-translational protein modification R-HSA-597592
Hh mutants abrogate ligand secretion R-HSA-5387390
Hedgehog ligand biogenesis R-HSA-5358346
Disease R-HSA-1643685
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
Activation of NF-kappaB in B cells R-HSA-1169091
Orc1 removal from chromatin R-HSA-68949
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of DVL R-HSA-4641258
MAPK1/MAPK3 signaling R-HSA-5684996
G1/S Transition R-HSA-69206
Ub-specific processing proteases R-HSA-5689880
Cell Cycle R-HSA-1640170
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Generic Transcription Pathway R-HSA-212436
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RAF/MAP kinase cascade R-HSA-5673001
G2/M Transition R-HSA-69275
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
Regulation of RUNX3 expression and activity R-HSA-8941858
Immune System R-HSA-168256
Vpu mediated degradation of CD4 R-HSA-180534
S Phase R-HSA-69242
Signaling by NOTCH4 R-HSA-9013694
Regulation of mitotic cell cycle R-HSA-453276
PCP/CE pathway R-HSA-4086400
Metabolism of polyamines R-HSA-351202
PTEN Regulation R-HSA-6807070
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication Pre-Initiation R-HSA-69002
Interferon alpha/beta signaling R-HSA-909733
Interleukin-1 family signaling R-HSA-446652
Cellular response to hypoxia R-HSA-1234174
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX3 R-HSA-8878159
ER-Phagosome pathway R-HSA-1236974
TCR signaling R-HSA-202403
Hedgehog 'off' state R-HSA-5610787
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
RNA Polymerase II Transcription R-HSA-73857
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Synthesis of DNA R-HSA-69239
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Anaphase R-HSA-68882
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic G2-G2/M phases R-HSA-453274
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH R-HSA-157118
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FCERI mediated NF-kB activation R-HSA-2871837
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
Vif-mediated degradation of APOBEC3G R-HSA-180585
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of amino acids and derivatives R-HSA-71291
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
Signaling by ROBO receptors R-HSA-376176
Downstream TCR signaling R-HSA-202424
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
p53-Dependent G1 DNA Damage Response R-HSA-69563
Switching of origins to a post-replicative state R-HSA-69052
Developmental Biology R-HSA-1266738
Separation of Sister Chromatids R-HSA-2467813
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants abrogate ligand secretion R-HSA-5387390
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by WNT R-HSA-195721
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX3 expression and activity R-HSA-8941858
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog 'off' state R-HSA-5610787
Separation of Sister Chromatids R-HSA-2467813
ER-Phagosome pathway R-HSA-1236974
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of polyamines R-HSA-351202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of DVL R-HSA-4641258
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog 'on' state R-HSA-5632684
S Phase R-HSA-69242
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RAF/MAP kinase cascade R-HSA-5673001
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Adaptive Immune System R-HSA-1280218
Stabilization of p53 R-HSA-69541
Degradation of GLI2 by the proteasome R-HSA-5610783
Cellular responses to stress R-HSA-2262752
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
Metabolism of RNA R-HSA-8953854
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic Metaphase and Anaphase R-HSA-2555396
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disorders of transmembrane transporters R-HSA-5619115
Asymmetric localization of PCP proteins R-HSA-4608870
Mitotic G1 phase and G1/S transition R-HSA-453279
Vpu mediated degradation of CD4 R-HSA-180534
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of beta-catenin by the destruction complex R-HSA-195253
Innate Immune System R-HSA-168249
Cellular response to chemical stress R-HSA-9711123
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Assembly of the pre-replicative complex R-HSA-68867
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCF dependent signaling in response to WNT R-HSA-201681
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of DNA R-HSA-69239
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G2-G2/M phases R-HSA-453274
Downstream TCR signaling R-HSA-202424
G1/S Transition R-HSA-69206
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
Metabolism of amino acids and derivatives R-HSA-71291
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Nervous system development R-HSA-9675108
Programmed Cell Death R-HSA-5357801
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH R-HSA-157118
Cell Cycle R-HSA-1640170
Signaling by ROBO receptors R-HSA-376176
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication R-HSA-69306
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of Apoptosis R-HSA-169911
Transport of small molecules R-HSA-382551
M Phase R-HSA-68886
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
PTEN Regulation R-HSA-6807070
Disease R-HSA-1643685
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular responses to stimuli R-HSA-8953897
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
C-type lectin receptors (CLRs) R-HSA-5621481
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Generic Transcription Pathway R-HSA-212436
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 signaling R-HSA-9020702
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by Interleukins R-HSA-449147
PCP/CE pathway R-HSA-4086400
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX3 R-HSA-8878159
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
FCERI mediated NF-kB activation R-HSA-2871837
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Transition R-HSA-69275
Metabolism R-HSA-1430728
Interferon Signaling R-HSA-913531
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
Apoptosis R-HSA-109581
Hh mutants are degraded by ERAD R-HSA-5362768
G2/M Checkpoints R-HSA-69481
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
Neddylation R-HSA-8951664
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCR signaling R-HSA-202403
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Interferon alpha/beta signaling R-HSA-909733
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
UCH proteinases R-HSA-5689603
Signaling by NOTCH4 R-HSA-9013694
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Axon guidance R-HSA-422475
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular response to hypoxia R-HSA-1234174
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
Degradation of AXIN R-HSA-4641257
Cyclin E associated events during G1/S transition R-HSA-69202
Developmental Biology R-HSA-1266738
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog ligand biogenesis R-HSA-5358346
Host Interactions of HIV factors R-HSA-162909
Signaling by Hedgehog R-HSA-5358351
Deubiquitination R-HSA-5688426
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signal Transduction R-HSA-162582
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of proteins R-HSA-392499
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Interleukins R-HSA-449147
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Asymmetric localization of PCP proteins R-HSA-4608870
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Immune System R-HSA-168256
Class I MHC mediated antigen processing & presentation R-HSA-983169
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Transition R-HSA-69275
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
Degradation of AXIN R-HSA-4641257
Disease R-HSA-1643685
Hh mutants abrogate ligand secretion R-HSA-5387390
C-type lectin receptors (CLRs) R-HSA-5621481
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
M Phase R-HSA-68886
Cellular response to chemical stress R-HSA-9711123
p53-Independent DNA Damage Response R-HSA-69610
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Programmed Cell Death R-HSA-5357801
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX3 R-HSA-8878159
Interferon alpha/beta signaling R-HSA-909733
Signaling by Hedgehog R-HSA-5358351
UCH proteinases R-HSA-5689603
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of mitotic cell cycle R-HSA-453276
Metabolism R-HSA-1430728
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transport of small molecules R-HSA-382551
Regulation of RAS by GAPs R-HSA-5658442
Stabilization of p53 R-HSA-69541
CLEC7A (Dectin-1) signaling R-HSA-5607764
Separation of Sister Chromatids R-HSA-2467813
Regulation of Apoptosis R-HSA-169911
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC-family proteins mediated transport R-HSA-382556
S Phase R-HSA-69242
HIV Infection R-HSA-162906
Antigen processing-Cross presentation R-HSA-1236975
Signaling by NOTCH4 R-HSA-9013694
TCR signaling R-HSA-202403
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Post-translational protein modification R-HSA-597592
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of proteins R-HSA-392499
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of GLI2 by the proteasome R-HSA-5610783
Generic Transcription Pathway R-HSA-212436
Mitotic Anaphase R-HSA-68882
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Synthesis of DNA R-HSA-69239
Interleukin-1 signaling R-HSA-9020702
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 family signaling R-HSA-446652
Vpu mediated degradation of CD4 R-HSA-180534
Axon guidance R-HSA-422475
Interferon Signaling R-HSA-913531
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular response to hypoxia R-HSA-1234174
Host Interactions of HIV factors R-HSA-162909
Signaling by ROBO receptors R-HSA-376176
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S Transition R-HSA-69206
ER-Phagosome pathway R-HSA-1236974
Cell Cycle R-HSA-1640170
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stress R-HSA-2262752
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Beta-catenin independent WNT signaling R-HSA-3858494
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Metaphase and Anaphase R-HSA-2555396
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of amino acids and derivatives R-HSA-71291
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'on' state R-HSA-5632684
Ub-specific processing proteases R-HSA-5689880
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog 'off' state R-HSA-5610787
Activation of NF-kappaB in B cells R-HSA-1169091
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants are degraded by ERAD R-HSA-5362768
Negative regulation of NOTCH4 signaling R-HSA-9604323
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle, Mitotic R-HSA-69278
Degradation of DVL R-HSA-4641258
Signal Transduction R-HSA-162582
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Cellular responses to stimuli R-HSA-8953897
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of PTEN stability and activity R-HSA-8948751
ABC transporter disorders R-HSA-5619084
Orc1 removal from chromatin R-HSA-68949
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by WNT R-HSA-195721
PTEN Regulation R-HSA-6807070
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Apoptosis R-HSA-109581
DNA Replication R-HSA-69306
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX1 R-HSA-8878171
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Neddylation R-HSA-8951664
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Assembly of the pre-replicative complex R-HSA-68867
PCP/CE pathway R-HSA-4086400

Expression Atlas ENSG00000204264
LRG display in Ensembl gene LRG_1328
NCBI gene (formerly Entrezgene) 5696
GeneCards 9545
HGNC Symbol HGNC:9545
MIM gene 177046
MIM morbid 256040
UniProtKB Gene Name X5D2R7
WikiGene 5696
Gene: PLAT
Ensembl ID : ENSG00000104368
Description: plasminogen activator, tissue type
Gene Synonyms:
1 APIs:
203 Possible Orthologues:

Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Signaling by PDGF R-HSA-186797
Dissolution of Fibrin Clot R-HSA-75205
Hemostasis R-HSA-109582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGF R-HSA-186797
Dissolution of Fibrin Clot R-HSA-75205
Signal Transduction R-HSA-162582
Dissolution of Fibrin Clot R-HSA-75205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGF R-HSA-186797
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Dissolution of Fibrin Clot R-HSA-75205
Signaling by PDGF R-HSA-186797
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Dissolution of Fibrin Clot R-HSA-75205
Hemostasis R-HSA-109582
Signaling by PDGF R-HSA-186797
Hemostasis R-HSA-109582
Dissolution of Fibrin Clot R-HSA-75205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by PDGF R-HSA-186797
Signal Transduction R-HSA-162582
Signaling by PDGF R-HSA-186797
Dissolution of Fibrin Clot R-HSA-75205
Hemostasis R-HSA-109582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Dissolution of Fibrin Clot R-HSA-75205
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Hemostasis R-HSA-109582
Signaling by PDGF R-HSA-186797
Hemostasis R-HSA-109582
Signaling by PDGF R-HSA-186797
Dissolution of Fibrin Clot R-HSA-75205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Dissolution of Fibrin Clot R-HSA-75205
Signal Transduction R-HSA-162582
Hemostasis R-HSA-109582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGF R-HSA-186797

Expression Atlas ENSG00000104368
LRG display in Ensembl gene LRG_570
NCBI gene (formerly Entrezgene) 5327
GeneCards 9051
HGNC Symbol HGNC:9051
MIM gene 173370
UniProtKB Gene Name P00750
WikiGene 5327
Gene: MMP2
Ensembl ID : ENSG00000087245
Description: matrix metallopeptidase 2
Gene Synonyms: CLG4,CLG4A,TBE-1
1 APIs:
210 Possible Orthologues:

Extracellular matrix organization R-HSA-1474244
EPH-Ephrin signaling R-HSA-2682334
Degradation of the extracellular matrix R-HSA-1474228
Axon guidance R-HSA-422475
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Metabolism of proteins R-HSA-392499
Signaling by Nuclear Receptors R-HSA-9006931
ESR-mediated signaling R-HSA-8939211
Nervous system development R-HSA-9675108
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
MAPK6/MAPK4 signaling R-HSA-5687128
Collagen degradation R-HSA-1442490
Extra-nuclear estrogen signaling R-HSA-9009391
MAPK6/MAPK4 signaling R-HSA-5687128
Collagen degradation R-HSA-1442490
Activation of Matrix Metalloproteinases R-HSA-1592389
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Axon guidance R-HSA-422475
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Metabolism of proteins R-HSA-392499
Degradation of the extracellular matrix R-HSA-1474228
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Nuclear Receptors R-HSA-9006931
Extracellular matrix organization R-HSA-1474244
EPH-Ephrin signaling R-HSA-2682334
Extra-nuclear estrogen signaling R-HSA-9009391
Immune System R-HSA-168256
ESR-mediated signaling R-HSA-8939211
Cytokine Signaling in Immune system R-HSA-1280215
EPH-Ephrin signaling R-HSA-2682334
ESR-mediated signaling R-HSA-8939211
Nervous system development R-HSA-9675108
Degradation of the extracellular matrix R-HSA-1474228
Activation of Matrix Metalloproteinases R-HSA-1592389
Developmental Biology R-HSA-1266738
Metabolism of proteins R-HSA-392499
Collagen degradation R-HSA-1442490
MAPK family signaling cascades R-HSA-5683057
Immune System R-HSA-168256
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Extracellular matrix organization R-HSA-1474244
Extra-nuclear estrogen signaling R-HSA-9009391
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Interleukins R-HSA-449147
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by Nuclear Receptors R-HSA-9006931
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of Matrix Metalloproteinases R-HSA-1592389
Immune System R-HSA-168256
ESR-mediated signaling R-HSA-8939211
Axon guidance R-HSA-422475
Extracellular matrix organization R-HSA-1474244
MAPK family signaling cascades R-HSA-5683057
Metabolism of proteins R-HSA-392499
EPH-Ephrin signaling R-HSA-2682334
Degradation of the extracellular matrix R-HSA-1474228
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Signaling by Nuclear Receptors R-HSA-9006931
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Extra-nuclear estrogen signaling R-HSA-9009391
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Collagen degradation R-HSA-1442490
Signaling by Interleukins R-HSA-449147
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by Nuclear Receptors R-HSA-9006931
Collagen degradation R-HSA-1442490
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Extracellular matrix organization R-HSA-1474244
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
EPH-ephrin mediated repulsion of cells R-HSA-3928665
ESR-mediated signaling R-HSA-8939211
EPH-Ephrin signaling R-HSA-2682334
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Extra-nuclear estrogen signaling R-HSA-9009391
Developmental Biology R-HSA-1266738
Degradation of the extracellular matrix R-HSA-1474228
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Nervous system development R-HSA-9675108
Signaling by Nuclear Receptors R-HSA-9006931
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Extra-nuclear estrogen signaling R-HSA-9009391
Cytokine Signaling in Immune system R-HSA-1280215
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
ESR-mediated signaling R-HSA-8939211
MAPK6/MAPK4 signaling R-HSA-5687128
Axon guidance R-HSA-422475
Extracellular matrix organization R-HSA-1474244
Collagen degradation R-HSA-1442490
EPH-Ephrin signaling R-HSA-2682334
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
MAPK family signaling cascades R-HSA-5683057
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
Metabolism of proteins R-HSA-392499
Degradation of the extracellular matrix R-HSA-1474228
EPH-ephrin mediated repulsion of cells R-HSA-3928665
MAPK family signaling cascades R-HSA-5683057
Extracellular matrix organization R-HSA-1474244
Signaling by Interleukins R-HSA-449147
ESR-mediated signaling R-HSA-8939211
Signaling by Nuclear Receptors R-HSA-9006931
Nervous system development R-HSA-9675108
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Metabolism of proteins R-HSA-392499
Degradation of the extracellular matrix R-HSA-1474228
Cytokine Signaling in Immune system R-HSA-1280215
MAPK6/MAPK4 signaling R-HSA-5687128
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
EPH-Ephrin signaling R-HSA-2682334
Collagen degradation R-HSA-1442490
Developmental Biology R-HSA-1266738
Activation of Matrix Metalloproteinases R-HSA-1592389
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Extra-nuclear estrogen signaling R-HSA-9009391
MAPK6/MAPK4 signaling R-HSA-5687128
Extracellular matrix organization R-HSA-1474244
Signal Transduction R-HSA-162582
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Interleukins R-HSA-449147
Collagen degradation R-HSA-1442490
Degradation of the extracellular matrix R-HSA-1474228
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
Metabolism of proteins R-HSA-392499
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Activation of Matrix Metalloproteinases R-HSA-1592389
Extra-nuclear estrogen signaling R-HSA-9009391
Immune System R-HSA-168256
EPH-Ephrin signaling R-HSA-2682334
ESR-mediated signaling R-HSA-8939211
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Developmental Biology R-HSA-1266738
Signaling by Nuclear Receptors R-HSA-9006931
Cytokine Signaling in Immune system R-HSA-1280215
Nervous system development R-HSA-9675108
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
MAPK family signaling cascades R-HSA-5683057
EPH-ephrin mediated repulsion of cells R-HSA-3928665
EPH-Ephrin signaling R-HSA-2682334
Signaling by Nuclear Receptors R-HSA-9006931
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Interleukins R-HSA-449147
Extracellular matrix organization R-HSA-1474244
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
Immune System R-HSA-168256
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of proteins R-HSA-392499
Collagen degradation R-HSA-1442490
ESR-mediated signaling R-HSA-8939211
Axon guidance R-HSA-422475
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Cytokine Signaling in Immune system R-HSA-1280215
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
Extracellular matrix organization R-HSA-1474244
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Immune System R-HSA-168256
MAPK family signaling cascades R-HSA-5683057
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Nuclear Receptors R-HSA-9006931
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
Activation of Matrix Metalloproteinases R-HSA-1592389
Axon guidance R-HSA-422475
Metabolism of proteins R-HSA-392499
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
EPH-Ephrin signaling R-HSA-2682334
ESR-mediated signaling R-HSA-8939211

Expression Atlas ENSG00000087245
NCBI gene (formerly Entrezgene) 4313
GeneCards 7166
HGNC Symbol HGNC:7166
MIM gene 120360
MIM morbid 259600
UniProtKB Gene Name P08253
WikiGene 4313
Gene: CMA1
Ensembl ID : ENSG00000092009
Description: chymase 1
Gene Synonyms:
1 APIs:
317 Possible Orthologues:

Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Peptide hormone metabolism R-HSA-2980736
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Peptide hormone metabolism R-HSA-2980736
Signaling by SCF-KIT R-HSA-1433557
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Peptide hormone metabolism R-HSA-2980736
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Activation of Matrix Metalloproteinases R-HSA-1592389
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Signaling by SCF-KIT R-HSA-1433557
Peptide hormone metabolism R-HSA-2980736
Degradation of the extracellular matrix R-HSA-1474228
Signal Transduction R-HSA-162582
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Peptide hormone metabolism R-HSA-2980736
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of proteins R-HSA-392499
Extracellular matrix organization R-HSA-1474244
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Activation of Matrix Metalloproteinases R-HSA-1592389
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Peptide hormone metabolism R-HSA-2980736
Signal Transduction R-HSA-162582
Signaling by SCF-KIT R-HSA-1433557
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Extracellular matrix organization R-HSA-1474244
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Extracellular matrix organization R-HSA-1474244
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by SCF-KIT R-HSA-1433557
Signal Transduction R-HSA-162582
Activation of Matrix Metalloproteinases R-HSA-1592389
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of proteins R-HSA-392499
Extracellular matrix organization R-HSA-1474244
Peptide hormone metabolism R-HSA-2980736
Signal Transduction R-HSA-162582
Signaling by SCF-KIT R-HSA-1433557
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Degradation of the extracellular matrix R-HSA-1474228
Activation of Matrix Metalloproteinases R-HSA-1592389
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activation of Matrix Metalloproteinases R-HSA-1592389
Peptide hormone metabolism R-HSA-2980736
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by SCF-KIT R-HSA-1433557
Metabolism of proteins R-HSA-392499
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Extracellular matrix organization R-HSA-1474244
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of proteins R-HSA-392499
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Signaling by SCF-KIT R-HSA-1433557

Expression Atlas ENSG00000092009
NCBI gene (formerly Entrezgene) 1215
GeneCards 2097
HGNC Symbol HGNC:2097
MIM gene 118938
UniProtKB Gene Name P23946
WikiGene 1215
Gene: PSMD11
Ensembl ID : ENSG00000108671
Description: proteasome 26S subunit, non-ATPase 11
Gene Synonyms: MGC3844,P44.5,RPN6,S9
5 APIs:
283 Possible Orthologues:

DNA Replication R-HSA-69306
Metabolism R-HSA-1430728
Programmed Cell Death R-HSA-5357801
Adaptive Immune System R-HSA-1280218
Activation of NF-kappaB in B cells R-HSA-1169091
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nuclear events mediated by NFE2L2 R-HSA-9759194
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of GLI1 by the proteasome R-HSA-5610780
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
MAPK family signaling cascades R-HSA-5683057
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'on' state R-HSA-5632684
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX1 R-HSA-8878171
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
Intracellular signaling by second messengers R-HSA-9006925
Separation of Sister Chromatids R-HSA-2467813
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle, Mitotic R-HSA-69278
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by WNT R-HSA-195721
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RAF/MAP kinase cascade R-HSA-5673001
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Hedgehog R-HSA-5358351
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
S Phase R-HSA-69242
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Immune System R-HSA-168256
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of RNA R-HSA-8953854
Stabilization of p53 R-HSA-69541
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular response to hypoxia R-HSA-1234174
Mitotic G1 phase and G1/S transition R-HSA-453279
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Downstream TCR signaling R-HSA-202424
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vpu mediated degradation of CD4 R-HSA-180534
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog 'off' state R-HSA-5610787
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism R-HSA-1430728
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
HIV Infection R-HSA-162906
ER-Phagosome pathway R-HSA-1236974
Apoptosis R-HSA-109581
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by NOTCH4 R-HSA-9013694
Neutrophil degranulation R-HSA-6798695
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
p53-Dependent G1 DNA Damage Response R-HSA-69563
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disease R-HSA-1643685
G1/S DNA Damage Checkpoints R-HSA-69615
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
Metabolism of polyamines R-HSA-351202
Deubiquitination R-HSA-5688426
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Metaphase and Anaphase R-HSA-2555396
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cyclin E associated events during G1/S transition R-HSA-69202
G2/M Transition R-HSA-69275
Degradation of AXIN R-HSA-4641257
Assembly of the pre-replicative complex R-HSA-68867
Hh mutants are degraded by ERAD R-HSA-5362768
Vif-mediated degradation of APOBEC3G R-HSA-180585
Generic Transcription Pathway R-HSA-212436
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stress R-HSA-2262752
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
Signal Transduction R-HSA-162582
Mitotic Anaphase R-HSA-68882
Ub-specific processing proteases R-HSA-5689880
TCR signaling R-HSA-202403
Cell Cycle Checkpoints R-HSA-69620
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RUNX3 expression and activity R-HSA-8941858
DNA Replication Pre-Initiation R-HSA-69002
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI2 by the proteasome R-HSA-5610783
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX2 R-HSA-8878166
ABC transporter disorders R-HSA-5619084
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX3 R-HSA-8878159
Defective CFTR causes cystic fibrosis R-HSA-5678895
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Gene expression (Transcription) R-HSA-74160
Signaling by ROBO receptors R-HSA-376176
Regulation of Apoptosis R-HSA-169911
UCH proteinases R-HSA-5689603
Cytokine Signaling in Immune system R-HSA-1280215
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
Hh mutants abrogate ligand secretion R-HSA-5387390
Synthesis of DNA R-HSA-69239
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of amino acids and derivatives R-HSA-71291
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Host Interactions of HIV factors R-HSA-162909
Nervous system development R-HSA-9675108
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Neddylation R-HSA-8951664
Negative regulation of NOTCH4 signaling R-HSA-9604323
MAPK6/MAPK4 signaling R-HSA-5687128
M Phase R-HSA-68886
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Dependent G1 DNA Damage Response R-HSA-69563
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI2 by the proteasome R-HSA-5610783
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
FCERI mediated NF-kB activation R-HSA-2871837
Programmed Cell Death R-HSA-5357801
DNA Replication R-HSA-69306
C-type lectin receptors (CLRs) R-HSA-5621481
Host Interactions of HIV factors R-HSA-162909
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCR signaling R-HSA-202403
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
Hedgehog 'on' state R-HSA-5632684
Mitotic Metaphase and Anaphase R-HSA-2555396
M Phase R-HSA-68886
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
Apoptosis R-HSA-109581
Disease R-HSA-1643685
Transcriptional regulation by RUNX3 R-HSA-8878159
Assembly of the pre-replicative complex R-HSA-68867
Deubiquitination R-HSA-5688426
Downstream TCR signaling R-HSA-202424
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Anaphase R-HSA-68882
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of DVL R-HSA-4641258
MAPK family signaling cascades R-HSA-5683057
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI1 by the proteasome R-HSA-5610780
RAF/MAP kinase cascade R-HSA-5673001
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle R-HSA-1640170
Metabolism of RNA R-HSA-8953854
Activation of NF-kappaB in B cells R-HSA-1169091
Hedgehog 'off' state R-HSA-5610787
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by NOTCH R-HSA-157118
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S DNA Damage Checkpoints R-HSA-69615
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Negative regulation of NOTCH4 signaling R-HSA-9604323
Neutrophil degranulation R-HSA-6798695
Gene expression (Transcription) R-HSA-74160
ABC transporter disorders R-HSA-5619084
Transport of small molecules R-HSA-382551
ER-Phagosome pathway R-HSA-1236974
Developmental Biology R-HSA-1266738
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Generic Transcription Pathway R-HSA-212436
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Interleukins R-HSA-449147
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
PIP3 activates AKT signaling R-HSA-1257604
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
Neddylation R-HSA-8951664
Vif-mediated degradation of APOBEC3G R-HSA-180585
Nervous system development R-HSA-9675108
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of proteins R-HSA-392499
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
Disorders of transmembrane transporters R-HSA-5619115
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle Checkpoints R-HSA-69620
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Cellular responses to stimuli R-HSA-8953897
Orc1 removal from chromatin R-HSA-68949
Metabolism of amino acids and derivatives R-HSA-71291
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle, Mitotic R-HSA-69278
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of polyamines R-HSA-351202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants are degraded by ERAD R-HSA-5362768
HIV Infection R-HSA-162906
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RAS by GAPs R-HSA-5658442
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
Cellular response to hypoxia R-HSA-1234174
Cellular response to chemical stress R-HSA-9711123
S Phase R-HSA-69242
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
Adaptive Immune System R-HSA-1280218
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Post-translational protein modification R-HSA-597592
Cellular responses to stress R-HSA-2262752
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S Transition R-HSA-69206
Synthesis of DNA R-HSA-69239
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Class I MHC mediated antigen processing & presentation R-HSA-983169
Intracellular signaling by second messengers R-HSA-9006925
PCP/CE pathway R-HSA-4086400
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by ROBO receptors R-HSA-376176
Mitotic G2-G2/M phases R-HSA-453274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH4 R-HSA-9013694
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mitotic cell cycle R-HSA-453276
Orc1 removal from chromatin R-HSA-68949
Vif-mediated degradation of APOBEC3G R-HSA-180585
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'on' state R-HSA-5632684
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Innate Immune System R-HSA-168249
Degradation of DVL R-HSA-4641258
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Cell Cycle, Mitotic R-HSA-69278
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by the B Cell Receptor (BCR) R-HSA-983705
KEAP1-NFE2L2 pathway R-HSA-9755511
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI2 by the proteasome R-HSA-5610783
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
Infectious disease R-HSA-5663205
Mitotic Metaphase and Anaphase R-HSA-2555396
DNA Replication Pre-Initiation R-HSA-69002
Class I MHC mediated antigen processing & presentation R-HSA-983169
Gene expression (Transcription) R-HSA-74160
Regulation of Apoptosis R-HSA-169911
Cellular response to chemical stress R-HSA-9711123
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Asymmetric localization of PCP proteins R-HSA-4608870
Neutrophil degranulation R-HSA-6798695
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ER-Phagosome pathway R-HSA-1236974
Signal Transduction R-HSA-162582
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by ROBO receptors R-HSA-376176
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RNA Polymerase II Transcription R-HSA-73857
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
TCR signaling R-HSA-202403
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX1 R-HSA-8878171
Intracellular signaling by second messengers R-HSA-9006925
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of proteins R-HSA-392499
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX3 expression and activity R-HSA-8941858
p53-Dependent G1 DNA Damage Response R-HSA-69563
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Independent DNA Damage Response R-HSA-69610
G1/S DNA Damage Checkpoints R-HSA-69615
Deubiquitination R-HSA-5688426
M Phase R-HSA-68886
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
Generic Transcription Pathway R-HSA-212436
Downstream TCR signaling R-HSA-202424
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Vpu mediated degradation of CD4 R-HSA-180534
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'off' state R-HSA-5610787
Nervous system development R-HSA-9675108
Cellular responses to stimuli R-HSA-8953897
Hedgehog ligand biogenesis R-HSA-5358346
Interleukin-1 signaling R-HSA-9020702
Separation of Sister Chromatids R-HSA-2467813
MAPK1/MAPK3 signaling R-HSA-5684996
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of GLI1 by the proteasome R-HSA-5610780
Mitotic G2-G2/M phases R-HSA-453274
UCH proteinases R-HSA-5689603
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of RNA R-HSA-8953854
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Stabilization of p53 R-HSA-69541
Regulation of RUNX2 expression and activity R-HSA-8939902
Programmed Cell Death R-HSA-5357801
Cell Cycle R-HSA-1640170
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cytokine Signaling in Immune system R-HSA-1280215
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
G2/M Transition R-HSA-69275
Disease R-HSA-1643685
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1/S Transition R-HSA-69206
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC-family proteins mediated transport R-HSA-382556
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic G1 phase and G1/S transition R-HSA-453279
Ub-specific processing proteases R-HSA-5689880
Disorders of transmembrane transporters R-HSA-5619115
Signaling by WNT R-HSA-195721
DNA Replication R-HSA-69306
ABC transporter disorders R-HSA-5619084
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to hypoxia R-HSA-1234174
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
Synthesis of DNA R-HSA-69239
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PCP/CE pathway R-HSA-4086400
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Interleukin-1 family signaling R-HSA-446652
Disorders of transmembrane transporters R-HSA-5619115
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
Mitotic Anaphase R-HSA-68882
Hh mutants are degraded by ERAD R-HSA-5362768
Adaptive Immune System R-HSA-1280218
MAPK6/MAPK4 signaling R-HSA-5687128
Asymmetric localization of PCP proteins R-HSA-4608870
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of AXIN R-HSA-4641257
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Defective CFTR causes cystic fibrosis R-HSA-5678895
HIV Infection R-HSA-162906
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
DNA Replication R-HSA-69306
Cellular responses to stimuli R-HSA-8953897
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of polyamines R-HSA-351202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
ABC-family proteins mediated transport R-HSA-382556
Activation of NF-kappaB in B cells R-HSA-1169091
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Developmental Biology R-HSA-1266738
Deubiquitination R-HSA-5688426
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by ROBO receptors R-HSA-376176
Separation of Sister Chromatids R-HSA-2467813
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by NOTCH R-HSA-157118
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Programmed Cell Death R-HSA-5357801
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
Class I MHC mediated antigen processing & presentation R-HSA-983169
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RUNX3 expression and activity R-HSA-8941858
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 signaling R-HSA-9020702
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated NF-kB activation R-HSA-2871837
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Generic Transcription Pathway R-HSA-212436
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Signaling by Interleukins R-HSA-449147
MAPK family signaling cascades R-HSA-5683057
Degradation of DVL R-HSA-4641258
Beta-catenin independent WNT signaling R-HSA-3858494
Innate Immune System R-HSA-168249
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Apoptosis R-HSA-109581
Intracellular signaling by second messengers R-HSA-9006925
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vpu mediated degradation of CD4 R-HSA-180534
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH4 R-HSA-9013694
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
RNA Polymerase II Transcription R-HSA-73857
Assembly of the pre-replicative complex R-HSA-68867
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Transition R-HSA-69275
Gene expression (Transcription) R-HSA-74160
Mitotic G1 phase and G1/S transition R-HSA-453279
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Synthesis of DNA R-HSA-69239
Cellular response to chemical stress R-HSA-9711123
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Axon guidance R-HSA-422475
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of Apoptosis R-HSA-169911
Immune System R-HSA-168256
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC transporter disorders R-HSA-5619084
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by WNT R-HSA-195721
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Hedgehog R-HSA-5358351
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Neddylation R-HSA-8951664
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Orc1 removal from chromatin R-HSA-68949
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
Stabilization of p53 R-HSA-69541
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
PIP3 activates AKT signaling R-HSA-1257604
G1/S DNA Damage Checkpoints R-HSA-69615
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog ligand biogenesis R-HSA-5358346
PCP/CE pathway R-HSA-4086400
Neutrophil degranulation R-HSA-6798695
Hedgehog 'on' state R-HSA-5632684
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Disease R-HSA-1643685
PTEN Regulation R-HSA-6807070
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S Transition R-HSA-69206
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of amino acids and derivatives R-HSA-71291
UCH proteinases R-HSA-5689603
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Switching of origins to a post-replicative state R-HSA-69052
Downstream TCR signaling R-HSA-202424
Cell Cycle Checkpoints R-HSA-69620
Post-translational protein modification R-HSA-597592
M Phase R-HSA-68886
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle R-HSA-1640170
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Neddylation R-HSA-8951664
Switching of origins to a post-replicative state R-HSA-69052
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle Checkpoints R-HSA-69620
ABC-family proteins mediated transport R-HSA-382556
Neutrophil degranulation R-HSA-6798695
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hh mutants are degraded by ERAD R-HSA-5362768
HIV Infection R-HSA-162906
Hedgehog 'on' state R-HSA-5632684
Mitotic G2-G2/M phases R-HSA-453274
Degradation of beta-catenin by the destruction complex R-HSA-195253
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 signaling R-HSA-9020702
Degradation of AXIN R-HSA-4641257
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of GLI2 by the proteasome R-HSA-5610783
Downstream TCR signaling R-HSA-202424
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle R-HSA-1640170
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
DNA Replication R-HSA-69306
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'off' state R-HSA-5610787
Regulation of Apoptosis R-HSA-169911
Generic Transcription Pathway R-HSA-212436
Programmed Cell Death R-HSA-5357801
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to chemical stress R-HSA-9711123
Intracellular signaling by second messengers R-HSA-9006925
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
Signal Transduction R-HSA-162582
Regulation of expression of SLITs and ROBOs R-HSA-9010553
UCH proteinases R-HSA-5689603
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Adaptive Immune System R-HSA-1280218
PTEN Regulation R-HSA-6807070
Degradation of GLI1 by the proteasome R-HSA-5610780
M Phase R-HSA-68886
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX3 R-HSA-8878159
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Disease R-HSA-1643685
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic Metaphase and Anaphase R-HSA-2555396
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of mitotic cell cycle R-HSA-453276
p53-Independent DNA Damage Response R-HSA-69610
Nervous system development R-HSA-9675108
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TCR signaling R-HSA-202403
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ER-Phagosome pathway R-HSA-1236974
Orc1 removal from chromatin R-HSA-68949
Cytokine Signaling in Immune system R-HSA-1280215
MAPK family signaling cascades R-HSA-5683057
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Nuclear events mediated by NFE2L2 R-HSA-9759194
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ub-specific processing proteases R-HSA-5689880
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Interleukins R-HSA-449147
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Developmental Biology R-HSA-1266738
Immune System R-HSA-168256
Disorders of transmembrane transporters R-HSA-5619115
Cyclin E associated events during G1/S transition R-HSA-69202
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic Anaphase R-HSA-68882
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants abrogate ligand secretion R-HSA-5387390
Deubiquitination R-HSA-5688426
PIP3 activates AKT signaling R-HSA-1257604
Host Interactions of HIV factors R-HSA-162909
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC transporter disorders R-HSA-5619084
Signaling by WNT R-HSA-195721
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX2 expression and activity R-HSA-8939902
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RAS by GAPs R-HSA-5658442
Innate Immune System R-HSA-168249
CLEC7A (Dectin-1) signaling R-HSA-5607764
G2/M Checkpoints R-HSA-69481
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by ROBO receptors R-HSA-376176
Signaling by NOTCH4 R-HSA-9013694
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
S Phase R-HSA-69242
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Post-translational protein modification R-HSA-597592
Synthesis of DNA R-HSA-69239
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
Cellular responses to stress R-HSA-2262752
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular responses to stimuli R-HSA-8953897
G2/M Transition R-HSA-69275
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Asymmetric localization of PCP proteins R-HSA-4608870
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of polyamines R-HSA-351202
Transport of small molecules R-HSA-382551
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S Transition R-HSA-69206
Gene expression (Transcription) R-HSA-74160
Interleukin-1 family signaling R-HSA-446652
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Assembly of the pre-replicative complex R-HSA-68867
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RNA Polymerase II Transcription R-HSA-73857
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Axon guidance R-HSA-422475
Apoptosis R-HSA-109581
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of RNA R-HSA-8953854
Metabolism of proteins R-HSA-392499
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX3 expression and activity R-HSA-8941858
Programmed Cell Death R-HSA-5357801
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of AXIN R-HSA-4641257
Axon guidance R-HSA-422475
Hedgehog 'on' state R-HSA-5632684
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of RUNX2 expression and activity R-HSA-8939902
Generic Transcription Pathway R-HSA-212436
Downstream TCR signaling R-HSA-202424
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by Hedgehog R-HSA-5358351
p53-Independent DNA Damage Response R-HSA-69610
Gene expression (Transcription) R-HSA-74160
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH4 R-HSA-9013694
ER-Phagosome pathway R-HSA-1236974
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI1 by the proteasome R-HSA-5610780
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
FCERI mediated NF-kB activation R-HSA-2871837
Class I MHC mediated antigen processing & presentation R-HSA-983169
Assembly of the pre-replicative complex R-HSA-68867
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Disorders of transmembrane transporters R-HSA-5619115
Negative regulation of NOTCH4 signaling R-HSA-9604323
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Adaptive Immune System R-HSA-1280218
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Activation of NF-kappaB in B cells R-HSA-1169091
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Post-translational protein modification R-HSA-597592
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Nuclear events mediated by NFE2L2 R-HSA-9759194
DNA Replication R-HSA-69306
Infectious disease R-HSA-5663205
HIV Infection R-HSA-162906
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX1 R-HSA-8878171
C-type lectin receptors (CLRs) R-HSA-5621481
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle, Mitotic R-HSA-69278
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'off' state R-HSA-5610787
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of DVL R-HSA-4641258
Signaling by WNT R-HSA-195721
Ub-specific processing proteases R-HSA-5689880
Neddylation R-HSA-8951664
Apoptosis R-HSA-109581
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
ABC transporter disorders R-HSA-5619084
Interleukin-1 signaling R-HSA-9020702
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Transition R-HSA-69275
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stimuli R-HSA-8953897
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
ABC-family proteins mediated transport R-HSA-382556
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by Interleukins R-HSA-449147
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
TCF dependent signaling in response to WNT R-HSA-201681
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Developmental Biology R-HSA-1266738
G2/M Checkpoints R-HSA-69481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RAS by GAPs R-HSA-5658442
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle R-HSA-1640170
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle Checkpoints R-HSA-69620
Neutrophil degranulation R-HSA-6798695
Metabolism R-HSA-1430728
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by ROBO receptors R-HSA-376176
Antigen processing-Cross presentation R-HSA-1236975
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
M Phase R-HSA-68886
Intracellular signaling by second messengers R-HSA-9006925
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Regulation of Apoptosis R-HSA-169911
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Anaphase R-HSA-68882
Regulation of PTEN stability and activity R-HSA-8948751
Switching of origins to a post-replicative state R-HSA-69052
Immune System R-HSA-168256
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
TCR signaling R-HSA-202403
Synthesis of DNA R-HSA-69239
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic Metaphase and Anaphase R-HSA-2555396
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX3 R-HSA-8878159
Host Interactions of HIV factors R-HSA-162909
Disease R-HSA-1643685
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vpu mediated degradation of CD4 R-HSA-180534
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nervous system development R-HSA-9675108
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G1/S Transition R-HSA-69206
Metabolism of polyamines R-HSA-351202
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of RNA R-HSA-8953854
Signaling by WNT R-HSA-195721
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of GLI2 by the proteasome R-HSA-5610783
Nervous system development R-HSA-9675108
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of amino acids and derivatives R-HSA-71291
TCR signaling R-HSA-202403
Synthesis of DNA R-HSA-69239
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
MAPK family signaling cascades R-HSA-5683057
Degradation of DVL R-HSA-4641258
Adaptive Immune System R-HSA-1280218
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
FCERI mediated NF-kB activation R-HSA-2871837
Activation of NF-kappaB in B cells R-HSA-1169091
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Axon guidance R-HSA-422475
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle, Mitotic R-HSA-69278
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Innate Immune System R-HSA-168249
Regulation of Apoptosis R-HSA-169911
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX3 R-HSA-8878159
Intracellular signaling by second messengers R-HSA-9006925
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of PTEN stability and activity R-HSA-8948751
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
Transport of small molecules R-HSA-382551
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
Deubiquitination R-HSA-5688426
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of RUNX2 expression and activity R-HSA-8939902
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Switching of origins to a post-replicative state R-HSA-69052
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
Separation of Sister Chromatids R-HSA-2467813
Defective CFTR causes cystic fibrosis R-HSA-5678895
Class I MHC mediated antigen processing & presentation R-HSA-983169
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Signaling by Interleukins R-HSA-449147
Signaling by ROBO receptors R-HSA-376176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PCP/CE pathway R-HSA-4086400
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog 'on' state R-HSA-5632684
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Neddylation R-HSA-8951664
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Gene expression (Transcription) R-HSA-74160
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
Ub-specific processing proteases R-HSA-5689880
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
HIV Infection R-HSA-162906
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Dependent G1 DNA Damage Response R-HSA-69563
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Neutrophil degranulation R-HSA-6798695
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Vif-mediated degradation of APOBEC3G R-HSA-180585
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent DNA Damage Response R-HSA-69610
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Cell Cycle Checkpoints R-HSA-69620
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Generic Transcription Pathway R-HSA-212436
Mitotic Metaphase and Anaphase R-HSA-2555396
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stimuli R-HSA-8953897
C-type lectin receptors (CLRs) R-HSA-5621481
S Phase R-HSA-69242
M Phase R-HSA-68886
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Mitotic Anaphase R-HSA-68882
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to hypoxia R-HSA-1234174
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
G2/M Checkpoints R-HSA-69481
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Cellular response to chemical stress R-HSA-9711123
Disease R-HSA-1643685
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic G1 phase and G1/S transition R-HSA-453279
Antigen processing-Cross presentation R-HSA-1236975
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
Vpu mediated degradation of CD4 R-HSA-180534
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of AXIN R-HSA-4641257
Metabolism R-HSA-1430728
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Generic Transcription Pathway R-HSA-212436
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle R-HSA-1640170
C-type lectin receptors (CLRs) R-HSA-5621481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog ligand biogenesis R-HSA-5358346
Apoptosis R-HSA-109581
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of PTEN stability and activity R-HSA-8948751
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Stabilization of p53 R-HSA-69541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ub-specific processing proteases R-HSA-5689880
G2/M Checkpoints R-HSA-69481
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by Hedgehog R-HSA-5358351
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cellular response to hypoxia R-HSA-1234174
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by NOTCH4 R-HSA-9013694
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
G2/M Transition R-HSA-69275
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC-family proteins mediated transport R-HSA-382556
Immune System R-HSA-168256
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
NIK-->noncanonical NF-kB signaling R-HSA-5676590
DNA Replication Pre-Initiation R-HSA-69002
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
S Phase R-HSA-69242
Transport of small molecules R-HSA-382551
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Deubiquitination R-HSA-5688426
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
Neddylation R-HSA-8951664
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stress R-HSA-2262752
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PTEN Regulation R-HSA-6807070
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle Checkpoints R-HSA-69620
Beta-catenin independent WNT signaling R-HSA-3858494
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Cyclin E associated events during G1/S transition R-HSA-69202
Axon guidance R-HSA-422475
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of Apoptosis R-HSA-169911
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of RNA R-HSA-8953854
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic Anaphase R-HSA-68882
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of polyamines R-HSA-351202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
HIV Infection R-HSA-162906
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Independent DNA Damage Response R-HSA-69610
PCP/CE pathway R-HSA-4086400
Nervous system development R-HSA-9675108
TCF dependent signaling in response to WNT R-HSA-201681
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Synthesis of DNA R-HSA-69239
Interleukin-1 family signaling R-HSA-446652
Signaling by ROBO receptors R-HSA-376176
M Phase R-HSA-68886
Hh mutants are degraded by ERAD R-HSA-5362768
Assembly of the pre-replicative complex R-HSA-68867
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
ABC transporter disorders R-HSA-5619084
Hedgehog 'off' state R-HSA-5610787
PIP3 activates AKT signaling R-HSA-1257604
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle, Mitotic R-HSA-69278
Adaptive Immune System R-HSA-1280218
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Cellular responses to stimuli R-HSA-8953897
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Dependent G1 DNA Damage Response R-HSA-69563
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Neutrophil degranulation R-HSA-6798695
Orc1 removal from chromatin R-HSA-68949
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hh mutants abrogate ligand secretion R-HSA-5387390
Signal Transduction R-HSA-162582
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication R-HSA-69306
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK6/MAPK4 signaling R-HSA-5687128
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI1 by the proteasome R-HSA-5610780
MAPK family signaling cascades R-HSA-5683057
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ub-specific processing proteases R-HSA-5689880
M Phase R-HSA-68886
Transcriptional regulation by RUNX3 R-HSA-8878159
Neddylation R-HSA-8951664
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of AXIN R-HSA-4641257
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream TCR signaling R-HSA-202424
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by ROBO receptors R-HSA-376176
Metabolism of proteins R-HSA-392499
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic Anaphase R-HSA-68882
Hh mutants are degraded by ERAD R-HSA-5362768
ABC transporter disorders R-HSA-5619084
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by WNT R-HSA-195721
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing-Cross presentation R-HSA-1236975
PTEN Regulation R-HSA-6807070
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of DVL R-HSA-4641258
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cell Cycle, Mitotic R-HSA-69278
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by NOTCH R-HSA-157118
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
p53-Independent DNA Damage Response R-HSA-69610
Cyclin E associated events during G1/S transition R-HSA-69202
ER-Phagosome pathway R-HSA-1236974
Neutrophil degranulation R-HSA-6798695
KEAP1-NFE2L2 pathway R-HSA-9755511
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G2/M Checkpoints R-HSA-69481
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of amino acids and derivatives R-HSA-71291
TCF dependent signaling in response to WNT R-HSA-201681
TCR signaling R-HSA-202403
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
Stabilization of p53 R-HSA-69541
PCP/CE pathway R-HSA-4086400
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
Orc1 removal from chromatin R-HSA-68949
Gene expression (Transcription) R-HSA-74160
Adaptive Immune System R-HSA-1280218
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Interleukin-1 signaling R-HSA-9020702
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G2-G2/M phases R-HSA-453274
UCH proteinases R-HSA-5689603
Innate Immune System R-HSA-168249
Separation of Sister Chromatids R-HSA-2467813
S Phase R-HSA-69242
Beta-catenin independent WNT signaling R-HSA-3858494
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Host Interactions of HIV factors R-HSA-162909
Transport of small molecules R-HSA-382551
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Vif-mediated degradation of APOBEC3G R-HSA-180585
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of beta-catenin by the destruction complex R-HSA-195253
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
RNA Polymerase II Transcription R-HSA-73857
Cellular response to hypoxia R-HSA-1234174
Assembly of the pre-replicative complex R-HSA-68867
Post-translational protein modification R-HSA-597592
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular response to chemical stress R-HSA-9711123
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stimuli R-HSA-8953897
Signaling by Interleukins R-HSA-449147
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK6/MAPK4 signaling R-HSA-5687128
Disease R-HSA-1643685
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by Hedgehog R-HSA-5358351
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle R-HSA-1640170
Deubiquitination R-HSA-5688426
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Axon guidance R-HSA-422475
ABC-family proteins mediated transport R-HSA-382556
Metabolism of RNA R-HSA-8953854
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Interleukin-1 family signaling R-HSA-446652
Hedgehog 'off' state R-HSA-5610787
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stress R-HSA-2262752
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
DNA Replication R-HSA-69306
Nuclear events mediated by NFE2L2 R-HSA-9759194
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Disorders of transmembrane transporters R-HSA-5619115
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G1/S Transition R-HSA-69206
Regulation of mitotic cell cycle R-HSA-453276
Regulation of RUNX3 expression and activity R-HSA-8941858
HIV Infection R-HSA-162906
Immune System R-HSA-168256
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism R-HSA-1430728
Orc1 removal from chromatin R-HSA-68949
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX1 R-HSA-8878171
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
Mitotic Metaphase and Anaphase R-HSA-2555396
Class I MHC mediated antigen processing & presentation R-HSA-983169
Stabilization of p53 R-HSA-69541
Synthesis of DNA R-HSA-69239
Apoptosis R-HSA-109581
Assembly of the pre-replicative complex R-HSA-68867
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic Anaphase R-HSA-68882
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle, Mitotic R-HSA-69278
Cyclin E associated events during G1/S transition R-HSA-69202
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing-Cross presentation R-HSA-1236975
Metabolism R-HSA-1430728
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX2 expression and activity R-HSA-8939902
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
Nervous system development R-HSA-9675108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle Checkpoints R-HSA-69620
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'on' state R-HSA-5632684
Neddylation R-HSA-8951664
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G1 phase and G1/S transition R-HSA-453279
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Infectious disease R-HSA-5663205
Programmed Cell Death R-HSA-5357801
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Disease R-HSA-1643685
Hedgehog 'off' state R-HSA-5610787
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PCP/CE pathway R-HSA-4086400
UCH proteinases R-HSA-5689603
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transcriptional regulation by RUNX2 R-HSA-8878166
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of DVL R-HSA-4641258
Degradation of GLI2 by the proteasome R-HSA-5610783
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G2/M Transition R-HSA-69275
Generic Transcription Pathway R-HSA-212436
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream TCR signaling R-HSA-202424
MAPK family signaling cascades R-HSA-5683057
Signaling by ROBO receptors R-HSA-376176
Separation of Sister Chromatids R-HSA-2467813
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
DNA Replication R-HSA-69306
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
S Phase R-HSA-69242
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Gene expression (Transcription) R-HSA-74160
Degradation of AXIN R-HSA-4641257
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by NOTCH R-HSA-157118
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stress R-HSA-2262752
ER-Phagosome pathway R-HSA-1236974
TCR signaling R-HSA-202403
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Axon guidance R-HSA-422475
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of RNA R-HSA-8953854
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
Cell Cycle R-HSA-1640170
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of beta-catenin by the destruction complex R-HSA-195253
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Interleukin-1 signaling R-HSA-9020702
HIV Infection R-HSA-162906
Cellular responses to stimuli R-HSA-8953897
Hedgehog ligand biogenesis R-HSA-5358346
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of PTEN stability and activity R-HSA-8948751
ABC transporter disorders R-HSA-5619084
Intracellular signaling by second messengers R-HSA-9006925
PTEN Regulation R-HSA-6807070
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Host Interactions of HIV factors R-HSA-162909
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neutrophil degranulation R-HSA-6798695
Transcriptional regulation by RUNX3 R-HSA-8878159
Signal Transduction R-HSA-162582
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of polyamines R-HSA-351202
Metabolism of proteins R-HSA-392499
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Adaptive Immune System R-HSA-1280218
Deubiquitination R-HSA-5688426
G1/S DNA Damage Checkpoints R-HSA-69615
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1 DNA Damage Response R-HSA-69563
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH4 R-HSA-9013694
Cytokine Signaling in Immune system R-HSA-1280215
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Cellular responses to stress R-HSA-2262752
Neddylation R-HSA-8951664
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Class I MHC mediated antigen processing & presentation R-HSA-983169
TCR signaling R-HSA-202403
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by ROBO receptors R-HSA-376176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
Hedgehog 'on' state R-HSA-5632684
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by NOTCH R-HSA-157118
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Synthesis of DNA R-HSA-69239
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Neutrophil degranulation R-HSA-6798695
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
Adaptive Immune System R-HSA-1280218
Signaling by the B Cell Receptor (BCR) R-HSA-983705
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Degradation of GLI1 by the proteasome R-HSA-5610780
ABC-family proteins mediated transport R-HSA-382556
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Host Interactions of HIV factors R-HSA-162909
FCERI mediated NF-kB activation R-HSA-2871837
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
Developmental Biology R-HSA-1266738
Metabolism of RNA R-HSA-8953854
UCH proteinases R-HSA-5689603
Cytokine Signaling in Immune system R-HSA-1280215
Vpu mediated degradation of CD4 R-HSA-180534
RNA Polymerase II Transcription R-HSA-73857
Signaling by NOTCH4 R-HSA-9013694
Innate Immune System R-HSA-168249
PIP3 activates AKT signaling R-HSA-1257604
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Gene expression (Transcription) R-HSA-74160
Transport of small molecules R-HSA-382551
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle Checkpoints R-HSA-69620
Hh mutants are degraded by ERAD R-HSA-5362768
M Phase R-HSA-68886
Interleukin-1 family signaling R-HSA-446652
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK family signaling cascades R-HSA-5683057
PCP/CE pathway R-HSA-4086400
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of DVL R-HSA-4641258
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of polyamines R-HSA-351202
G2/M Checkpoints R-HSA-69481
C-type lectin receptors (CLRs) R-HSA-5621481
ABC transporter disorders R-HSA-5619084
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ub-specific processing proteases R-HSA-5689880
Hedgehog 'off' state R-HSA-5610787
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RAS by GAPs R-HSA-5658442
Stabilization of p53 R-HSA-69541
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Independent DNA Damage Response R-HSA-69610
Beta-catenin independent WNT signaling R-HSA-3858494
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Immune System R-HSA-168256
TCF dependent signaling in response to WNT R-HSA-201681
Cellular response to chemical stress R-HSA-9711123
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Axon guidance R-HSA-422475
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic Anaphase R-HSA-68882
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
Cell Cycle R-HSA-1640170
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transcriptional regulation by RUNX3 R-HSA-8878159
Generic Transcription Pathway R-HSA-212436
Activation of NF-kappaB in B cells R-HSA-1169091
S Phase R-HSA-69242
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Programmed Cell Death R-HSA-5357801
Intracellular signaling by second messengers R-HSA-9006925
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
Nervous system development R-HSA-9675108
Downstream TCR signaling R-HSA-202424
Post-translational protein modification R-HSA-597592
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism R-HSA-1430728
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
HIV Infection R-HSA-162906
Cellular response to hypoxia R-HSA-1234174
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
KEAP1-NFE2L2 pathway R-HSA-9755511
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vif-mediated degradation of APOBEC3G R-HSA-180585
Assembly of the pre-replicative complex R-HSA-68867
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hedgehog ligand biogenesis R-HSA-5358346
G1/S Transition R-HSA-69206
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of PTEN stability and activity R-HSA-8948751
PTEN Regulation R-HSA-6807070
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by WNT R-HSA-195721
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent G1/S DNA damage checkpoint R-HSA-69613

Expression Atlas ENSG00000108671
NCBI gene (formerly Entrezgene) 5717
GeneCards 9556
HGNC Symbol HGNC:9556
MIM gene 604449
UniProtKB Gene Name O00231
WikiGene 5717
Gene: FAP
Ensembl ID : ENSG00000078098
Description: fibroblast activation protein alpha
Gene Synonyms: DPPIV
3 APIs:
127 Possible Orthologues:

Expression Atlas ENSG00000078098
NCBI gene (formerly Entrezgene) 2191
GeneCards 3590
HGNC Symbol HGNC:3590
MIM gene 600403
UniProtKB Gene Name Q12884
WikiGene 2191