Gene: PTGS2
Ensembl ID : ENSG00000073756
Description: prostaglandin-endoperoxide synthase 2
Gene Synonyms: COX2
73 APIs:
240 Possible Orthologues:

Metabolism R-HSA-1430728
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Nicotinamide salvaging R-HSA-197264
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Immune System R-HSA-168256
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of lipids R-HSA-556833
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Synthesis of 15-eicosatetraenoic acid derivatives R-HSA-2142770
Signaling by Interleukins R-HSA-449147
Interleukin-10 signaling R-HSA-6783783
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism of vitamins and cofactors R-HSA-196854
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Nicotinate metabolism R-HSA-196807
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Fatty acid metabolism R-HSA-8978868
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Metabolism R-HSA-1430728
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Fatty acid metabolism R-HSA-8978868
Cytokine Signaling in Immune system R-HSA-1280215
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Interleukin-10 signaling R-HSA-6783783
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Metabolism of lipids R-HSA-556833
Metabolism of vitamins and cofactors R-HSA-196854
Nicotinamide salvaging R-HSA-197264
Synthesis of 15-eicosatetraenoic acid derivatives R-HSA-2142770
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Immune System R-HSA-168256
Nicotinate metabolism R-HSA-196807
Signaling by Interleukins R-HSA-449147
Interleukin-10 signaling R-HSA-6783783
Immune System R-HSA-168256
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Nicotinamide salvaging R-HSA-197264
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Signaling by Interleukins R-HSA-449147
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Arachidonic acid metabolism R-HSA-2142753
Synthesis of 15-eicosatetraenoic acid derivatives R-HSA-2142770
Metabolism of lipids R-HSA-556833
Fatty acid metabolism R-HSA-8978868
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Cytokine Signaling in Immune system R-HSA-1280215
Nicotinate metabolism R-HSA-196807
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism R-HSA-1430728
Immune System R-HSA-168256
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Arachidonic acid metabolism R-HSA-2142753
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Nicotinamide salvaging R-HSA-197264
Synthesis of 15-eicosatetraenoic acid derivatives R-HSA-2142770
Metabolism of vitamins and cofactors R-HSA-196854
Fatty acid metabolism R-HSA-8978868
Metabolism R-HSA-1430728
Nicotinate metabolism R-HSA-196807
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Metabolism of lipids R-HSA-556833
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Interleukin-10 signaling R-HSA-6783783
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Immune System R-HSA-168256
Fatty acid metabolism R-HSA-8978868
Synthesis of 15-eicosatetraenoic acid derivatives R-HSA-2142770
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Signaling by Interleukins R-HSA-449147
Nicotinate metabolism R-HSA-196807
Metabolism R-HSA-1430728
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Interleukin-10 signaling R-HSA-6783783
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Metabolism of lipids R-HSA-556833
Nicotinamide salvaging R-HSA-197264
Metabolism of vitamins and cofactors R-HSA-196854
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Fatty acid metabolism R-HSA-8978868
Metabolism of lipids R-HSA-556833
Immune System R-HSA-168256
Arachidonic acid metabolism R-HSA-2142753
Nicotinate metabolism R-HSA-196807
Synthesis of 15-eicosatetraenoic acid derivatives R-HSA-2142770
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Interleukin-10 signaling R-HSA-6783783
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Signaling by Interleukins R-HSA-449147
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Metabolism of vitamins and cofactors R-HSA-196854
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Nicotinamide salvaging R-HSA-197264
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Metabolism of vitamins and cofactors R-HSA-196854
Nicotinate metabolism R-HSA-196807
Metabolism R-HSA-1430728
Immune System R-HSA-168256
Synthesis of 15-eicosatetraenoic acid derivatives R-HSA-2142770
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Arachidonic acid metabolism R-HSA-2142753
Metabolism of lipids R-HSA-556833
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Nicotinamide salvaging R-HSA-197264
Fatty acid metabolism R-HSA-8978868
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Interleukin-10 signaling R-HSA-6783783
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Cytokine Signaling in Immune system R-HSA-1280215
Nicotinamide salvaging R-HSA-197264
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Signaling by Interleukins R-HSA-449147
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Interleukin-10 signaling R-HSA-6783783
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Metabolism of vitamins and cofactors R-HSA-196854
Immune System R-HSA-168256
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Synthesis of 15-eicosatetraenoic acid derivatives R-HSA-2142770
Fatty acid metabolism R-HSA-8978868
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Nicotinate metabolism R-HSA-196807
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Immune System R-HSA-168256
Metabolism of lipids R-HSA-556833
Nicotinate metabolism R-HSA-196807
Synthesis of 15-eicosatetraenoic acid derivatives R-HSA-2142770
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Metabolism R-HSA-1430728
Nicotinamide salvaging R-HSA-197264
Fatty acid metabolism R-HSA-8978868
Interleukin-10 signaling R-HSA-6783783
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by Interleukins R-HSA-449147
Metabolism of vitamins and cofactors R-HSA-196854
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Cytokine Signaling in Immune system R-HSA-1280215
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Interleukin-10 signaling R-HSA-6783783
Metabolism of vitamins and cofactors R-HSA-196854
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of 15-eicosatetraenoic acid derivatives R-HSA-2142770
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism R-HSA-1430728
Fatty acid metabolism R-HSA-8978868
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Signaling by Interleukins R-HSA-449147
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Immune System R-HSA-168256
Nicotinamide salvaging R-HSA-197264
Nicotinate metabolism R-HSA-196807
Metabolism of lipids R-HSA-556833

Expression Atlas ENSG00000073756
NCBI gene (formerly Entrezgene) 5743
GeneCards 9605
HGNC Symbol HGNC:9605
MIM gene 600262
UniProtKB Gene Name Q6ZYK7
WikiGene 5743
Gene: CYP46A1
Ensembl ID : ENSG00000036530
Description: cytochrome P450 family 46 subfamily A member 1
Gene Synonyms: CYP46
1 APIs:
260 Possible Orthologues:

Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Phase I - Functionalization of compounds R-HSA-211945
Endogenous sterols R-HSA-211976
Synthesis of bile acids and bile salts R-HSA-192105
Biological oxidations R-HSA-211859
Cytochrome P450 - arranged by substrate type R-HSA-211897
Bile acid and bile salt metabolism R-HSA-194068
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Metabolism of steroids R-HSA-8957322
Phase I - Functionalization of compounds R-HSA-211945
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of lipids R-HSA-556833
Bile acid and bile salt metabolism R-HSA-194068
Endogenous sterols R-HSA-211976
Synthesis of bile acids and bile salts R-HSA-192105
Metabolism of lipids R-HSA-556833
Bile acid and bile salt metabolism R-HSA-194068
Metabolism R-HSA-1430728
Cytochrome P450 - arranged by substrate type R-HSA-211897
Synthesis of bile acids and bile salts R-HSA-192105
Metabolism of steroids R-HSA-8957322
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Endogenous sterols R-HSA-211976
Bile acid and bile salt metabolism R-HSA-194068
Synthesis of bile acids and bile salts R-HSA-192105
Metabolism R-HSA-1430728
Endogenous sterols R-HSA-211976
Phase I - Functionalization of compounds R-HSA-211945
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Metabolism of lipids R-HSA-556833
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of steroids R-HSA-8957322
Biological oxidations R-HSA-211859
Endogenous sterols R-HSA-211976
Bile acid and bile salt metabolism R-HSA-194068
Biological oxidations R-HSA-211859
Synthesis of bile acids and bile salts R-HSA-192105
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Metabolism of lipids R-HSA-556833
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Cytochrome P450 - arranged by substrate type R-HSA-211897
Synthesis of bile acids and bile salts R-HSA-192105
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Bile acid and bile salt metabolism R-HSA-194068
Cytochrome P450 - arranged by substrate type R-HSA-211897
Endogenous sterols R-HSA-211976
Metabolism of steroids R-HSA-8957322
Metabolism of steroids R-HSA-8957322
Metabolism of lipids R-HSA-556833
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Synthesis of bile acids and bile salts R-HSA-192105
Bile acid and bile salt metabolism R-HSA-194068
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Cytochrome P450 - arranged by substrate type R-HSA-211897
Endogenous sterols R-HSA-211976
Metabolism of lipids R-HSA-556833
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Biological oxidations R-HSA-211859
Bile acid and bile salt metabolism R-HSA-194068
Synthesis of bile acids and bile salts R-HSA-192105
Cytochrome P450 - arranged by substrate type R-HSA-211897
Endogenous sterols R-HSA-211976
Synthesis of bile acids and bile salts R-HSA-192105
Metabolism R-HSA-1430728
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Phase I - Functionalization of compounds R-HSA-211945
Cytochrome P450 - arranged by substrate type R-HSA-211897
Bile acid and bile salt metabolism R-HSA-194068
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Metabolism of lipids R-HSA-556833
Biological oxidations R-HSA-211859

Expression Atlas ENSG00000036530
NCBI gene (formerly Entrezgene) 10858
GeneCards 2641
HGNC Symbol HGNC:2641
MIM gene 604087
UniProtKB Gene Name Q9Y6A2
WikiGene 10858
Gene: PTPN11
Ensembl ID : ENSG00000179295
Description: protein tyrosine phosphatase non-receptor type 11
Gene Synonyms: BPTP3,NS1,PTP2C,SH-PTP2,SHP-2,SHP2
1 APIs:
209 Possible Orthologues:

MET activates PTPN11 R-HSA-8865999
IRS-related events triggered by IGF1R R-HSA-2428928
GAB1 signalosome R-HSA-180292
Signaling by FGFR1 R-HSA-5654736
PIP3 activates AKT signaling R-HSA-1257604
Downstream signaling of activated FGFR3 R-HSA-5654708
FRS-mediated FGFR4 signaling R-HSA-5654712
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MyD88-independent TLR4 cascade R-HSA-166166
Signal regulatory protein family interactions R-HSA-391160
Nervous system development R-HSA-9675108
Interleukin-1 family signaling R-HSA-446652
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cell-Cell communication R-HSA-1500931
Hemostasis R-HSA-109582
Prolactin receptor signaling R-HSA-1170546
Negative regulation of FGFR4 signaling R-HSA-5654733
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by PDGF R-HSA-186797
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Signaling by EGFR R-HSA-177929
Signaling by FGFR1 R-HSA-5654736
FRS-mediated FGFR3 signaling R-HSA-5654706
Interleukin-20 family signaling R-HSA-8854691
PECAM1 interactions R-HSA-210990
IGF1R signaling cascade R-HSA-2428924
Signaling by CSF3 (G-CSF) R-HSA-9674555
MAPK1/MAPK3 signaling R-HSA-5684996
Infectious disease R-HSA-5663205
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
MET activates PTPN11 R-HSA-8865999
Interleukin-37 signaling R-HSA-9008059
FLT3 signaling in disease R-HSA-9682385
Spry regulation of FGF signaling R-HSA-1295596
Interleukin-6 family signaling R-HSA-6783589
CTLA4 inhibitory signaling R-HSA-389513
Intracellular signaling by second messengers R-HSA-9006925
Gene expression (Transcription) R-HSA-74160
Interferon alpha/beta signaling R-HSA-909733
Interferon Signaling R-HSA-913531
Downstream signaling of activated FGFR1 R-HSA-5654687
Tie2 Signaling R-HSA-210993
Downstream signaling of activated FGFR4 R-HSA-5654716
Toll-like Receptor Cascades R-HSA-168898
Insulin receptor signalling cascade R-HSA-74751
IRS-mediated signalling R-HSA-112399
Interferon gamma signaling R-HSA-877300
PI3K Cascade R-HSA-109704
FLT3 Signaling R-HSA-9607240
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
MAPK1 (ERK2) activation R-HSA-112411
Platelet activation, signaling and aggregation R-HSA-76002
STAT5 Activation R-HSA-9645135
Interleukin-6 signaling R-HSA-1059683
Signaling by Interleukins R-HSA-449147
PD-1 signaling R-HSA-389948
Netrin-1 signaling R-HSA-373752
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
FRS-mediated FGFR1 signaling R-HSA-5654693
GPVI-mediated activation cascade R-HSA-114604
PI-3K cascade:FGFR4 R-HSA-5654720
PI-3K cascade:FGFR2 R-HSA-5654695
Negative regulation of FGFR2 signaling R-HSA-5654727
Signal Transduction R-HSA-162582
Regulation of IFNG signaling R-HSA-877312
Signaling by Insulin receptor R-HSA-74752
Downstream signaling of activated FGFR2 R-HSA-5654696
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by FGFR3 R-HSA-5654741
Transcriptional regulation by RUNX1 R-HSA-8878171
Netrin mediated repulsion signals R-HSA-418886
FRS-mediated FGFR2 signaling R-HSA-5654700
MAPK3 (ERK1) activation R-HSA-110056
RAF-independent MAPK1/3 activation R-HSA-112409
GAB1 signalosome R-HSA-180292
Negative regulation of FGFR1 signaling R-HSA-5654726
Innate Immune System R-HSA-168249
Signaling by NTRK2 (TRKB) R-HSA-9006115
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Immune System R-HSA-168256
PI-3K cascade:FGFR3 R-HSA-5654710
Adaptive Immune System R-HSA-1280218
Signaling by FGFR4 R-HSA-5654743
RET signaling R-HSA-8853659
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Costimulation by the CD28 family R-HSA-388841
Cytokine Signaling in Immune system R-HSA-1280215
PI-3K cascade:FGFR1 R-HSA-5654689
Downstream signal transduction R-HSA-186763
Generic Transcription Pathway R-HSA-212436
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by MET R-HSA-6806834
Platelet homeostasis R-HSA-418346
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
Signaling by SCF-KIT R-HSA-1433557
SARS-CoV-2 Infection R-HSA-9694516
Axon guidance R-HSA-422475
IRS-related events triggered by IGF1R R-HSA-2428928
Regulation of IFNA/IFNB signaling R-HSA-912694
Negative regulation of the PI3K/AKT network R-HSA-199418
Disease R-HSA-1643685
SARS-CoV Infections R-HSA-9679506
Platelet sensitization by LDL R-HSA-432142
Signaling by Leptin R-HSA-2586552
Signaling by FGFR2 R-HSA-5654738
SARS-CoV-2-host interactions R-HSA-9705683
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR R-HSA-190236
Signaling by NTRKs R-HSA-166520
Adaptive Immune System R-HSA-1280218
Downstream signaling of activated FGFR3 R-HSA-5654708
Axon guidance R-HSA-422475
Insulin receptor signalling cascade R-HSA-74751
Signaling by EGFR R-HSA-177929
Signal regulatory protein family interactions R-HSA-391160
Downstream signal transduction R-HSA-186763
IGF1R signaling cascade R-HSA-2428924
Developmental Biology R-HSA-1266738
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
GAB1 signalosome R-HSA-180292
Infectious disease R-HSA-5663205
Toll-like Receptor Cascades R-HSA-168898
Nervous system development R-HSA-9675108
PI3K Cascade R-HSA-109704
Interleukin-6 family signaling R-HSA-6783589
Costimulation by the CD28 family R-HSA-388841
FLT3 Signaling R-HSA-9607240
Downstream signaling of activated FGFR2 R-HSA-5654696
Cell-Cell communication R-HSA-1500931
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Platelet homeostasis R-HSA-418346
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Interleukin-37 signaling R-HSA-9008059
Signaling by MET R-HSA-6806834
Netrin mediated repulsion signals R-HSA-418886
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by FGFR3 R-HSA-5654741
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
MAPK3 (ERK1) activation R-HSA-110056
Signaling by FGFR2 R-HSA-5654738
Disease R-HSA-1643685
Regulation of IFNA/IFNB signaling R-HSA-912694
Signaling by Interleukins R-HSA-449147
SARS-CoV-2-host interactions R-HSA-9705683
IRS-mediated signalling R-HSA-112399
STAT5 Activation R-HSA-9645135
Hemostasis R-HSA-109582
Netrin-1 signaling R-HSA-373752
Signaling by FGFR4 R-HSA-5654743
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by CSF3 (G-CSF) R-HSA-9674555
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by Leptin R-HSA-2586552
Interferon alpha/beta signaling R-HSA-909733
Signaling by PDGF R-HSA-186797
Intracellular signaling by second messengers R-HSA-9006925
FRS-mediated FGFR3 signaling R-HSA-5654706
PD-1 signaling R-HSA-389948
PI-3K cascade:FGFR3 R-HSA-5654710
PIP3 activates AKT signaling R-HSA-1257604
PI3K/AKT Signaling in Cancer R-HSA-2219528
SARS-CoV-2 Infection R-HSA-9694516
Signaling by SCF-KIT R-HSA-1433557
Platelet activation, signaling and aggregation R-HSA-76002
Cytokine Signaling in Immune system R-HSA-1280215
FRS-mediated FGFR1 signaling R-HSA-5654693
MyD88-independent TLR4 cascade R-HSA-166166
Generic Transcription Pathway R-HSA-212436
Platelet sensitization by LDL R-HSA-432142
PI-3K cascade:FGFR1 R-HSA-5654689
Negative regulation of FGFR4 signaling R-HSA-5654733
Tie2 Signaling R-HSA-210993
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Interleukin-20 family signaling R-HSA-8854691
Downstream signaling of activated FGFR1 R-HSA-5654687
RET signaling R-HSA-8853659
Negative regulation of FGFR1 signaling R-HSA-5654726
IRS-related events triggered by IGF1R R-HSA-2428928
Interferon gamma signaling R-HSA-877300
GPVI-mediated activation cascade R-HSA-114604
Cell surface interactions at the vascular wall R-HSA-202733
Regulation of IFNG signaling R-HSA-877312
Gene expression (Transcription) R-HSA-74160
MAPK1 (ERK2) activation R-HSA-112411
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
Negative regulation of FGFR2 signaling R-HSA-5654727
MET activates PTPN11 R-HSA-8865999
Transcriptional regulation by RUNX1 R-HSA-8878171
CTLA4 inhibitory signaling R-HSA-389513
Signaling by NTRK2 (TRKB) R-HSA-9006115
Prolactin receptor signaling R-HSA-1170546
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
FRS-mediated FGFR4 signaling R-HSA-5654712
Spry regulation of FGF signaling R-HSA-1295596
Signaling by NTRKs R-HSA-166520
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Interleukin-6 signaling R-HSA-1059683
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by FGFR1 R-HSA-5654736
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Regulation of RUNX1 Expression and Activity R-HSA-8934593
MAPK family signaling cascades R-HSA-5683057
Interferon Signaling R-HSA-913531
SARS-CoV Infections R-HSA-9679506
Interleukin-1 family signaling R-HSA-446652
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Signaling by FGFR R-HSA-190236
Signaling by Insulin receptor R-HSA-74752
PECAM1 interactions R-HSA-210990
RAF-independent MAPK1/3 activation R-HSA-112409
RNA Polymerase II Transcription R-HSA-73857
FRS-mediated FGFR2 signaling R-HSA-5654700
FLT3 signaling in disease R-HSA-9682385
PI-3K cascade:FGFR2 R-HSA-5654695
PI-3K cascade:FGFR4 R-HSA-5654720
Netrin-1 signaling R-HSA-373752
Signaling by Insulin receptor R-HSA-74752
Signaling by MET R-HSA-6806834
Platelet sensitization by LDL R-HSA-432142
RET signaling R-HSA-8853659
Signaling by NTRK2 (TRKB) R-HSA-9006115
Signaling by FGFR1 R-HSA-5654736
Toll-like Receptor Cascades R-HSA-168898
Signaling by Interleukins R-HSA-449147
STAT5 Activation R-HSA-9645135
Transcriptional regulation by RUNX1 R-HSA-8878171
FLT3 Signaling R-HSA-9607240
Negative regulation of FGFR3 signaling R-HSA-5654732
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
Intracellular signaling by second messengers R-HSA-9006925
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by FGFR3 R-HSA-5654741
Signal Transduction R-HSA-162582
FRS-mediated FGFR4 signaling R-HSA-5654712
IGF1R signaling cascade R-HSA-2428924
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
GAB1 signalosome R-HSA-180292
Interleukin-1 family signaling R-HSA-446652
Prolactin receptor signaling R-HSA-1170546
Signaling by SCF-KIT R-HSA-1433557
Signaling by EGFR R-HSA-177929
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Disease R-HSA-1643685
Signal regulatory protein family interactions R-HSA-391160
Hemostasis R-HSA-109582
Signaling by FGFR2 R-HSA-5654738
Innate Immune System R-HSA-168249
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by PDGF R-HSA-186797
Signaling by FGFR R-HSA-190236
FRS-mediated FGFR2 signaling R-HSA-5654700
Interferon gamma signaling R-HSA-877300
Netrin mediated repulsion signals R-HSA-418886
Cell surface interactions at the vascular wall R-HSA-202733
Cell-Cell communication R-HSA-1500931
Negative regulation of FGFR4 signaling R-HSA-5654733
Developmental Biology R-HSA-1266738
Signaling by CSF3 (G-CSF) R-HSA-9674555
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Downstream signaling of activated FGFR1 R-HSA-5654687
Cytokine Signaling in Immune system R-HSA-1280215
FLT3 signaling in disease R-HSA-9682385
Interleukin-20 family signaling R-HSA-8854691
PI-3K cascade:FGFR1 R-HSA-5654689
Interleukin-37 signaling R-HSA-9008059
Nervous system development R-HSA-9675108
Interferon alpha/beta signaling R-HSA-909733
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
Interferon Signaling R-HSA-913531
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PD-1 signaling R-HSA-389948
Signaling by Leptin R-HSA-2586552
MAPK3 (ERK1) activation R-HSA-110056
Downstream signal transduction R-HSA-186763
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by NTRKs R-HSA-166520
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
Negative regulation of FGFR1 signaling R-HSA-5654726
MAPK1 (ERK2) activation R-HSA-112411
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR4 R-HSA-5654743
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
MAPK1/MAPK3 signaling R-HSA-5684996
IRS-related events triggered by IGF1R R-HSA-2428928
IRS-mediated signalling R-HSA-112399
Downstream signaling of activated FGFR2 R-HSA-5654696
SARS-CoV-2-host interactions R-HSA-9705683
PI-3K cascade:FGFR4 R-HSA-5654720
Regulation of IFNG signaling R-HSA-877312
PI-3K cascade:FGFR3 R-HSA-5654710
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K Cascade R-HSA-109704
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
SARS-CoV Infections R-HSA-9679506
Immune System R-HSA-168256
PI3K/AKT Signaling in Cancer R-HSA-2219528
RNA Polymerase II Transcription R-HSA-73857
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
CTLA4 inhibitory signaling R-HSA-389513
Spry regulation of FGF signaling R-HSA-1295596
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Regulation of IFNA/IFNB signaling R-HSA-912694
PECAM1 interactions R-HSA-210990
Platelet homeostasis R-HSA-418346
Platelet activation, signaling and aggregation R-HSA-76002
Costimulation by the CD28 family R-HSA-388841
Downstream signaling of activated FGFR3 R-HSA-5654708
FRS-mediated FGFR3 signaling R-HSA-5654706
Interleukin-6 family signaling R-HSA-6783589
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
GPVI-mediated activation cascade R-HSA-114604
RAF-independent MAPK1/3 activation R-HSA-112409
Downstream signaling of activated FGFR4 R-HSA-5654716
Tie2 Signaling R-HSA-210993
Interleukin-6 signaling R-HSA-1059683
FRS-mediated FGFR1 signaling R-HSA-5654693
SARS-CoV-2 Infection R-HSA-9694516
Insulin receptor signalling cascade R-HSA-74751
Costimulation by the CD28 family R-HSA-388841
Downstream signaling of activated FGFR1 R-HSA-5654687
PI-3K cascade:FGFR1 R-HSA-5654689
FRS-mediated FGFR2 signaling R-HSA-5654700
RET signaling R-HSA-8853659
Signal regulatory protein family interactions R-HSA-391160
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Regulation of IFNG signaling R-HSA-877312
Negative regulation of FGFR3 signaling R-HSA-5654732
Infectious disease R-HSA-5663205
Interleukin-6 signaling R-HSA-1059683
SARS-CoV Infections R-HSA-9679506
FRS-mediated FGFR3 signaling R-HSA-5654706
FRS-mediated FGFR4 signaling R-HSA-5654712
Netrin-1 signaling R-HSA-373752
Interferon Signaling R-HSA-913531
SARS-CoV-2 Infection R-HSA-9694516
PD-1 signaling R-HSA-389948
Signaling by FGFR1 R-HSA-5654736
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by Leptin R-HSA-2586552
Interferon alpha/beta signaling R-HSA-909733
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Signal Transduction R-HSA-162582
Downstream signaling of activated FGFR2 R-HSA-5654696
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR R-HSA-190236
Transcriptional regulation by RUNX1 R-HSA-8878171
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Developmental Biology R-HSA-1266738
Signaling by FGFR3 R-HSA-5654741
Negative regulation of the PI3K/AKT network R-HSA-199418
MAPK3 (ERK1) activation R-HSA-110056
Negative regulation of FGFR1 signaling R-HSA-5654726
IGF1R signaling cascade R-HSA-2428924
Cytokine Signaling in Immune system R-HSA-1280215
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by MET R-HSA-6806834
MAPK family signaling cascades R-HSA-5683057
Platelet sensitization by LDL R-HSA-432142
RNA Polymerase II Transcription R-HSA-73857
IRS-mediated signalling R-HSA-112399
PI-3K cascade:FGFR3 R-HSA-5654710
PECAM1 interactions R-HSA-210990
IRS-related events triggered by IGF1R R-HSA-2428928
FLT3 Signaling R-HSA-9607240
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by NTRK2 (TRKB) R-HSA-9006115
SARS-CoV-2-host interactions R-HSA-9705683
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
MET activates PTPN11 R-HSA-8865999
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FLT3 signaling in disease R-HSA-9682385
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
Signaling by NTRKs R-HSA-166520
Gene expression (Transcription) R-HSA-74160
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Netrin mediated repulsion signals R-HSA-418886
Signaling by Insulin receptor R-HSA-74752
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Negative regulation of FGFR2 signaling R-HSA-5654727
Spry regulation of FGF signaling R-HSA-1295596
MyD88-independent TLR4 cascade R-HSA-166166
CTLA4 inhibitory signaling R-HSA-389513
GPVI-mediated activation cascade R-HSA-114604
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Negative regulation of FGFR4 signaling R-HSA-5654733
Nervous system development R-HSA-9675108
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by CSF3 (G-CSF) R-HSA-9674555
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Platelet homeostasis R-HSA-418346
Prolactin receptor signaling R-HSA-1170546
STAT5 Activation R-HSA-9645135
PI3K Cascade R-HSA-109704
Regulation of IFNA/IFNB signaling R-HSA-912694
Innate Immune System R-HSA-168249
Signaling by EGFR R-HSA-177929
Interleukin-37 signaling R-HSA-9008059
Interferon gamma signaling R-HSA-877300
Signaling by FGFR2 R-HSA-5654738
Interleukin-6 family signaling R-HSA-6783589
Signaling by Interleukins R-HSA-449147
Intracellular signaling by second messengers R-HSA-9006925
Immune System R-HSA-168256
MAPK1 (ERK2) activation R-HSA-112411
Signaling by SCF-KIT R-HSA-1433557
Toll-like Receptor Cascades R-HSA-168898
Downstream signal transduction R-HSA-186763
FRS-mediated FGFR1 signaling R-HSA-5654693
GAB1 signalosome R-HSA-180292
Tie2 Signaling R-HSA-210993
Generic Transcription Pathway R-HSA-212436
Interleukin-20 family signaling R-HSA-8854691
Cell-Cell communication R-HSA-1500931
Platelet activation, signaling and aggregation R-HSA-76002
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
PIP3 activates AKT signaling R-HSA-1257604
RAF-independent MAPK1/3 activation R-HSA-112409
Cell surface interactions at the vascular wall R-HSA-202733
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR4 R-HSA-5654743
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Signaling by PDGF R-HSA-186797
Interleukin-1 family signaling R-HSA-446652
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
PI-3K cascade:FGFR4 R-HSA-5654720
Hemostasis R-HSA-109582
IGF1R signaling cascade R-HSA-2428924
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by MET R-HSA-6806834
FRS-mediated FGFR3 signaling R-HSA-5654706
GPVI-mediated activation cascade R-HSA-114604
Axon guidance R-HSA-422475
Downstream signaling of activated FGFR1 R-HSA-5654687
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by FGFR2 R-HSA-5654738
Generic Transcription Pathway R-HSA-212436
Spry regulation of FGF signaling R-HSA-1295596
Netrin-1 signaling R-HSA-373752
Interferon gamma signaling R-HSA-877300
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Infectious disease R-HSA-5663205
Interleukin-37 signaling R-HSA-9008059
RET signaling R-HSA-8853659
Signaling by Leptin R-HSA-2586552
Platelet sensitization by LDL R-HSA-432142
Costimulation by the CD28 family R-HSA-388841
Downstream signal transduction R-HSA-186763
SARS-CoV-2 Infection R-HSA-9694516
Signaling by CSF3 (G-CSF) R-HSA-9674555
GAB1 signalosome R-HSA-180292
Signaling by NTRKs R-HSA-166520
Interleukin-1 family signaling R-HSA-446652
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
RNA Polymerase II Transcription R-HSA-73857
IRS-mediated signalling R-HSA-112399
Platelet homeostasis R-HSA-418346
Signaling by SCF-KIT R-HSA-1433557
Cytokine Signaling in Immune system R-HSA-1280215
Developmental Biology R-HSA-1266738
Negative regulation of FGFR2 signaling R-HSA-5654727
Interleukin-6 family signaling R-HSA-6783589
PI-3K cascade:FGFR3 R-HSA-5654710
Signaling by PDGF R-HSA-186797
MAPK1 (ERK2) activation R-HSA-112411
Signaling by FGFR4 R-HSA-5654743
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Gene expression (Transcription) R-HSA-74160
Interleukin-20 family signaling R-HSA-8854691
PIP3 activates AKT signaling R-HSA-1257604
Downstream signaling of activated FGFR2 R-HSA-5654696
Netrin mediated repulsion signals R-HSA-418886
Downstream signaling of activated FGFR4 R-HSA-5654716
SARS-CoV Infections R-HSA-9679506
PI3K Cascade R-HSA-109704
FRS-mediated FGFR2 signaling R-HSA-5654700
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
FLT3 Signaling R-HSA-9607240
FRS-mediated FGFR1 signaling R-HSA-5654693
FRS-mediated FGFR4 signaling R-HSA-5654712
Cell-Cell communication R-HSA-1500931
Transcriptional regulation by RUNX1 R-HSA-8878171
Prolactin receptor signaling R-HSA-1170546
Interferon Signaling R-HSA-913531
Toll-like Receptor Cascades R-HSA-168898
Interferon alpha/beta signaling R-HSA-909733
Adaptive Immune System R-HSA-1280218
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by FGFR3 R-HSA-5654741
Tie2 Signaling R-HSA-210993
Disease R-HSA-1643685
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Regulation of RUNX1 Expression and Activity R-HSA-8934593
MET activates PTPN11 R-HSA-8865999
Signaling by Insulin receptor R-HSA-74752
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
MyD88-independent TLR4 cascade R-HSA-166166
PI-3K cascade:FGFR4 R-HSA-5654720
Regulation of IFNG signaling R-HSA-877312
Interleukin-6 signaling R-HSA-1059683
Signal Transduction R-HSA-162582
Signaling by NTRK2 (TRKB) R-HSA-9006115
Cell surface interactions at the vascular wall R-HSA-202733
Insulin receptor signalling cascade R-HSA-74751
Hemostasis R-HSA-109582
SARS-CoV-2-host interactions R-HSA-9705683
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
Platelet activation, signaling and aggregation R-HSA-76002
STAT5 Activation R-HSA-9645135
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by EGFR R-HSA-177929
PD-1 signaling R-HSA-389948
Regulation of IFNA/IFNB signaling R-HSA-912694
Signaling by FGFR1 R-HSA-5654736
Signal regulatory protein family interactions R-HSA-391160
MAPK family signaling cascades R-HSA-5683057
PI-3K cascade:FGFR1 R-HSA-5654689
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by FGFR R-HSA-190236
Negative regulation of FGFR4 signaling R-HSA-5654733
Immune System R-HSA-168256
MAPK3 (ERK1) activation R-HSA-110056
Intracellular signaling by second messengers R-HSA-9006925
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
CTLA4 inhibitory signaling R-HSA-389513
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PECAM1 interactions R-HSA-210990
FLT3 signaling in disease R-HSA-9682385
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Interleukins R-HSA-449147
Signaling by FGFR3 R-HSA-5654741
Immune System R-HSA-168256
STAT5 Activation R-HSA-9645135
MAPK family signaling cascades R-HSA-5683057
RET signaling R-HSA-8853659
IRS-related events triggered by IGF1R R-HSA-2428928
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by EGFR R-HSA-177929
MAPK1 (ERK2) activation R-HSA-112411
CTLA4 inhibitory signaling R-HSA-389513
Signaling by PDGF R-HSA-186797
Signaling by CSF3 (G-CSF) R-HSA-9674555
Innate Immune System R-HSA-168249
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Hemostasis R-HSA-109582
Intracellular signaling by second messengers R-HSA-9006925
GPVI-mediated activation cascade R-HSA-114604
Platelet activation, signaling and aggregation R-HSA-76002
MAPK3 (ERK1) activation R-HSA-110056
Negative regulation of FGFR4 signaling R-HSA-5654733
FRS-mediated FGFR4 signaling R-HSA-5654712
Interleukin-6 signaling R-HSA-1059683
Cell surface interactions at the vascular wall R-HSA-202733
Interleukin-1 family signaling R-HSA-446652
Interferon Signaling R-HSA-913531
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Regulation of RUNX1 Expression and Activity R-HSA-8934593
IGF1R signaling cascade R-HSA-2428924
Interferon gamma signaling R-HSA-877300
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K Cascade R-HSA-109704
PI3K/AKT Signaling in Cancer R-HSA-2219528
Toll-like Receptor Cascades R-HSA-168898
Downstream signaling of activated FGFR3 R-HSA-5654708
Downstream signaling of activated FGFR4 R-HSA-5654716
Prolactin receptor signaling R-HSA-1170546
Signaling by NTRKs R-HSA-166520
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by FGFR R-HSA-190236
Disease R-HSA-1643685
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Adaptive Immune System R-HSA-1280218
Signaling by NTRK2 (TRKB) R-HSA-9006115
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by MET R-HSA-6806834
Signaling by Leptin R-HSA-2586552
Platelet homeostasis R-HSA-418346
Signaling by FGFR1 R-HSA-5654736
Netrin mediated repulsion signals R-HSA-418886
Signal regulatory protein family interactions R-HSA-391160
PI-3K cascade:FGFR2 R-HSA-5654695
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by Insulin receptor R-HSA-74752
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Platelet sensitization by LDL R-HSA-432142
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SARS-CoV Infections R-HSA-9679506
Downstream signal transduction R-HSA-186763
Signaling by SCF-KIT R-HSA-1433557
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
Infectious disease R-HSA-5663205
PI-3K cascade:FGFR4 R-HSA-5654720
SARS-CoV-2 Infection R-HSA-9694516
Transcriptional regulation by RUNX1 R-HSA-8878171
FLT3 Signaling R-HSA-9607240
FRS-mediated FGFR1 signaling R-HSA-5654693
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
PECAM1 interactions R-HSA-210990
Developmental Biology R-HSA-1266738
MyD88-independent TLR4 cascade R-HSA-166166
FRS-mediated FGFR3 signaling R-HSA-5654706
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Negative regulation of FGFR2 signaling R-HSA-5654727
Downstream signaling of activated FGFR2 R-HSA-5654696
Spry regulation of FGF signaling R-HSA-1295596
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
Signaling by FGFR2 R-HSA-5654738
MET activates PTPN11 R-HSA-8865999
PI-3K cascade:FGFR3 R-HSA-5654710
Interleukin-20 family signaling R-HSA-8854691
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
IRS-mediated signalling R-HSA-112399
RAF-independent MAPK1/3 activation R-HSA-112409
Costimulation by the CD28 family R-HSA-388841
Netrin-1 signaling R-HSA-373752
Cell-Cell communication R-HSA-1500931
Cytokine Signaling in Immune system R-HSA-1280215
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by FGFR4 R-HSA-5654743
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Axon guidance R-HSA-422475
Downstream signaling of activated FGFR1 R-HSA-5654687
Regulation of IFNG signaling R-HSA-877312
Tie2 Signaling R-HSA-210993
Interferon alpha/beta signaling R-HSA-909733
FLT3 signaling in disease R-HSA-9682385
Signal Transduction R-HSA-162582
PD-1 signaling R-HSA-389948
Interleukin-6 family signaling R-HSA-6783589
Interleukin-37 signaling R-HSA-9008059
Signaling by Interleukins R-HSA-449147
Negative regulation of FGFR3 signaling R-HSA-5654732
Generic Transcription Pathway R-HSA-212436
Regulation of IFNA/IFNB signaling R-HSA-912694
Insulin receptor signalling cascade R-HSA-74751
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
GPVI-mediated activation cascade R-HSA-114604
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by CSF3 (G-CSF) R-HSA-9674555
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FLT3 signaling in disease R-HSA-9682385
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-6 signaling R-HSA-1059683
Netrin-1 signaling R-HSA-373752
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of FGFR2 signaling R-HSA-5654727
Cell surface interactions at the vascular wall R-HSA-202733
Platelet homeostasis R-HSA-418346
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by FGFR4 R-HSA-5654743
RAF-independent MAPK1/3 activation R-HSA-112409
Regulation of IFNA/IFNB signaling R-HSA-912694
Developmental Biology R-HSA-1266738
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by PDGF R-HSA-186797
Interleukin-6 family signaling R-HSA-6783589
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Hemostasis R-HSA-109582
Interferon Signaling R-HSA-913531
Adaptive Immune System R-HSA-1280218
Downstream signaling of activated FGFR3 R-HSA-5654708
PI-3K cascade:FGFR3 R-HSA-5654710
Infectious disease R-HSA-5663205
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Nervous system development R-HSA-9675108
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
SARS-CoV-2 Infection R-HSA-9694516
Tie2 Signaling R-HSA-210993
MAPK1 (ERK2) activation R-HSA-112411
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by FGFR R-HSA-190236
Interferon gamma signaling R-HSA-877300
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Interleukin-20 family signaling R-HSA-8854691
Signaling by NTRKs R-HSA-166520
MET activates PTPN11 R-HSA-8865999
Cell-Cell communication R-HSA-1500931
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR2 R-HSA-5654738
Downstream signaling of activated FGFR2 R-HSA-5654696
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
MyD88-independent TLR4 cascade R-HSA-166166
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Interleukin-1 family signaling R-HSA-446652
Interleukin-37 signaling R-HSA-9008059
IRS-related events triggered by IGF1R R-HSA-2428928
PI-3K cascade:FGFR1 R-HSA-5654689
Generic Transcription Pathway R-HSA-212436
Signaling by EGFR R-HSA-177929
Interferon alpha/beta signaling R-HSA-909733
FRS-mediated FGFR4 signaling R-HSA-5654712
Axon guidance R-HSA-422475
PECAM1 interactions R-HSA-210990
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Insulin receptor R-HSA-74752
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Immune System R-HSA-168256
PI-3K cascade:FGFR4 R-HSA-5654720
Insulin receptor signalling cascade R-HSA-74751
PI3K/AKT Signaling in Cancer R-HSA-2219528
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
FLT3 Signaling R-HSA-9607240
RET signaling R-HSA-8853659
MAPK family signaling cascades R-HSA-5683057
Toll-like Receptor Cascades R-HSA-168898
Regulation of IFNG signaling R-HSA-877312
Signaling by FGFR1 R-HSA-5654736
Costimulation by the CD28 family R-HSA-388841
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PIP3 activates AKT signaling R-HSA-1257604
MAPK3 (ERK1) activation R-HSA-110056
Regulation of RUNX1 Expression and Activity R-HSA-8934593
FRS-mediated FGFR3 signaling R-HSA-5654706
IRS-mediated signalling R-HSA-112399
PD-1 signaling R-HSA-389948
Signal regulatory protein family interactions R-HSA-391160
STAT5 Activation R-HSA-9645135
Prolactin receptor signaling R-HSA-1170546
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Downstream signal transduction R-HSA-186763
Negative regulation of FGFR1 signaling R-HSA-5654726
Negative regulation of FGFR3 signaling R-HSA-5654732
PI-3K cascade:FGFR2 R-HSA-5654695
Netrin mediated repulsion signals R-HSA-418886
Innate Immune System R-HSA-168249
PI3K Cascade R-HSA-109704
Platelet sensitization by LDL R-HSA-432142
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by Leptin R-HSA-2586552
Spry regulation of FGF signaling R-HSA-1295596
Signaling by NTRK2 (TRKB) R-HSA-9006115
Signaling by Interleukins R-HSA-449147
Platelet activation, signaling and aggregation R-HSA-76002
Downstream signaling of activated FGFR1 R-HSA-5654687
FRS-mediated FGFR1 signaling R-HSA-5654693
GAB1 signalosome R-HSA-180292
MAPK1/MAPK3 signaling R-HSA-5684996
CTLA4 inhibitory signaling R-HSA-389513
Signaling by MET R-HSA-6806834
Signaling by SCF-KIT R-HSA-1433557
SARS-CoV Infections R-HSA-9679506
Signaling by FGFR3 R-HSA-5654741
Interleukin-37 signaling R-HSA-9008059
PI-3K cascade:FGFR1 R-HSA-5654689
FRS-mediated FGFR3 signaling R-HSA-5654706
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
MAPK family signaling cascades R-HSA-5683057
Interleukin-6 signaling R-HSA-1059683
Transcriptional regulation by RUNX1 R-HSA-8878171
Toll-like Receptor Cascades R-HSA-168898
Insulin receptor signalling cascade R-HSA-74751
Signaling by SCF-KIT R-HSA-1433557
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
SARS-CoV Infections R-HSA-9679506
FLT3 Signaling R-HSA-9607240
Cell-Cell communication R-HSA-1500931
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signal regulatory protein family interactions R-HSA-391160
Disease R-HSA-1643685
Downstream signal transduction R-HSA-186763
STAT5 Activation R-HSA-9645135
Signaling by Interleukins R-HSA-449147
Signaling by FGFR2 R-HSA-5654738
PI-3K cascade:FGFR4 R-HSA-5654720
MAPK3 (ERK1) activation R-HSA-110056
Immune System R-HSA-168256
Signaling by EGFR R-HSA-177929
Interferon gamma signaling R-HSA-877300
Interferon Signaling R-HSA-913531
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by Leptin R-HSA-2586552
Interleukin-6 family signaling R-HSA-6783589
Signaling by MET R-HSA-6806834
PI3K Cascade R-HSA-109704
FLT3 signaling in disease R-HSA-9682385
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
MAPK1/MAPK3 signaling R-HSA-5684996
PD-1 signaling R-HSA-389948
Signaling by Insulin receptor R-HSA-74752
Interferon alpha/beta signaling R-HSA-909733
Signaling by NTRKs R-HSA-166520
Innate Immune System R-HSA-168249
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Downstream signaling of activated FGFR4 R-HSA-5654716
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
Signaling by CSF3 (G-CSF) R-HSA-9674555
Developmental Biology R-HSA-1266738
GPVI-mediated activation cascade R-HSA-114604
RET signaling R-HSA-8853659
Platelet sensitization by LDL R-HSA-432142
Netrin mediated repulsion signals R-HSA-418886
GAB1 signalosome R-HSA-180292
PECAM1 interactions R-HSA-210990
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 family signaling R-HSA-446652
PIP3 activates AKT signaling R-HSA-1257604
Regulation of IFNG signaling R-HSA-877312
Axon guidance R-HSA-422475
Regulation of IFNA/IFNB signaling R-HSA-912694
Interleukin-20 family signaling R-HSA-8854691
Negative regulation of the PI3K/AKT network R-HSA-199418
Negative regulation of FGFR1 signaling R-HSA-5654726
MAPK1 (ERK2) activation R-HSA-112411
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
IRS-related events triggered by IGF1R R-HSA-2428928
MET activates PTPN11 R-HSA-8865999
Signaling by FGFR3 R-HSA-5654741
Signaling by PDGF R-HSA-186797
Negative regulation of FGFR4 signaling R-HSA-5654733
CTLA4 inhibitory signaling R-HSA-389513
FRS-mediated FGFR4 signaling R-HSA-5654712
RAF-independent MAPK1/3 activation R-HSA-112409
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Signaling by FGFR R-HSA-190236
FRS-mediated FGFR2 signaling R-HSA-5654700
IRS-mediated signalling R-HSA-112399
Netrin-1 signaling R-HSA-373752
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Platelet homeostasis R-HSA-418346
PI-3K cascade:FGFR3 R-HSA-5654710
Hemostasis R-HSA-109582
IGF1R signaling cascade R-HSA-2428924
FRS-mediated FGFR1 signaling R-HSA-5654693
Costimulation by the CD28 family R-HSA-388841
Negative regulation of FGFR3 signaling R-HSA-5654732
Negative regulation of FGFR2 signaling R-HSA-5654727
Platelet activation, signaling and aggregation R-HSA-76002
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Downstream signaling of activated FGFR3 R-HSA-5654708
Spry regulation of FGF signaling R-HSA-1295596
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Generic Transcription Pathway R-HSA-212436
Downstream signaling of activated FGFR2 R-HSA-5654696
Signal Transduction R-HSA-162582
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Tie2 Signaling R-HSA-210993
SARS-CoV-2 Infection R-HSA-9694516
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by FGFR4 R-HSA-5654743
Cell surface interactions at the vascular wall R-HSA-202733
Prolactin receptor signaling R-HSA-1170546
PI-3K cascade:FGFR2 R-HSA-5654695
Intracellular signaling by second messengers R-HSA-9006925
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRK2 (TRKB) R-HSA-9006115
Platelet homeostasis R-HSA-418346
Signaling by Insulin receptor R-HSA-74752
Platelet activation, signaling and aggregation R-HSA-76002
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
PIP3 activates AKT signaling R-HSA-1257604
RET signaling R-HSA-8853659
STAT5 Activation R-HSA-9645135
PI3K/AKT Signaling in Cancer R-HSA-2219528
Interleukin-37 signaling R-HSA-9008059
PI-3K cascade:FGFR3 R-HSA-5654710
Interleukin-1 family signaling R-HSA-446652
Netrin-1 signaling R-HSA-373752
FRS-mediated FGFR4 signaling R-HSA-5654712
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Insulin receptor signalling cascade R-HSA-74751
Regulation of IFNG signaling R-HSA-877312
Signaling by Interleukins R-HSA-449147
Signaling by EGFR R-HSA-177929
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Regulation of RUNX1 Expression and Activity R-HSA-8934593
PI3K Cascade R-HSA-109704
Disease R-HSA-1643685
Prolactin receptor signaling R-HSA-1170546
MET activates PTPN11 R-HSA-8865999
FLT3 Signaling R-HSA-9607240
FRS-mediated FGFR3 signaling R-HSA-5654706
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by FGFR1 R-HSA-5654736
GAB1 signalosome R-HSA-180292
Costimulation by the CD28 family R-HSA-388841
Spry regulation of FGF signaling R-HSA-1295596
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Platelet sensitization by LDL R-HSA-432142
MAPK3 (ERK1) activation R-HSA-110056
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK1 (ERK2) activation R-HSA-112411
Adaptive Immune System R-HSA-1280218
Signaling by NTRK2 (TRKB) R-HSA-9006115
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Toll-like Receptor Cascades R-HSA-168898
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FRS-mediated FGFR2 signaling R-HSA-5654700
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
Downstream signaling of activated FGFR2 R-HSA-5654696
RAF-independent MAPK1/3 activation R-HSA-112409
Negative regulation of FGFR4 signaling R-HSA-5654733
PI-3K cascade:FGFR4 R-HSA-5654720
Downstream signaling of activated FGFR3 R-HSA-5654708
FRS-mediated FGFR1 signaling R-HSA-5654693
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Intracellular signaling by second messengers R-HSA-9006925
PI-3K cascade:FGFR2 R-HSA-5654695
IGF1R signaling cascade R-HSA-2428924
Downstream signal transduction R-HSA-186763
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Nervous system development R-HSA-9675108
Negative regulation of FGFR2 signaling R-HSA-5654727
SARS-CoV-2 Infection R-HSA-9694516
MyD88-independent TLR4 cascade R-HSA-166166
CTLA4 inhibitory signaling R-HSA-389513
Signaling by FGFR3 R-HSA-5654741
GPVI-mediated activation cascade R-HSA-114604
Gene expression (Transcription) R-HSA-74160
Negative regulation of the PI3K/AKT network R-HSA-199418
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
Tie2 Signaling R-HSA-210993
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Signaling by PDGF R-HSA-186797
Signaling by FGFR2 R-HSA-5654738
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by Leptin R-HSA-2586552
Signaling by MET R-HSA-6806834
Interferon Signaling R-HSA-913531
Interferon alpha/beta signaling R-HSA-909733
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Interleukin-20 family signaling R-HSA-8854691
Regulation of IFNA/IFNB signaling R-HSA-912694
Signal regulatory protein family interactions R-HSA-391160
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Generic Transcription Pathway R-HSA-212436
Hemostasis R-HSA-109582
Cell surface interactions at the vascular wall R-HSA-202733
SARS-CoV-2-host interactions R-HSA-9705683
PD-1 signaling R-HSA-389948
PI-3K cascade:FGFR1 R-HSA-5654689
RNA Polymerase II Transcription R-HSA-73857
PECAM1 interactions R-HSA-210990
Signaling by SCF-KIT R-HSA-1433557
Interleukin-6 family signaling R-HSA-6783589
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by FGFR R-HSA-190236
Signaling by NTRKs R-HSA-166520
Negative regulation of FGFR1 signaling R-HSA-5654726
SARS-CoV Infections R-HSA-9679506
Interleukin-6 signaling R-HSA-1059683
IRS-mediated signalling R-HSA-112399
Interferon gamma signaling R-HSA-877300
FLT3 signaling in disease R-HSA-9682385
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by CSF3 (G-CSF) R-HSA-9674555
Immune System R-HSA-168256
Signaling by FGFR4 R-HSA-5654743
Cell-Cell communication R-HSA-1500931
Netrin mediated repulsion signals R-HSA-418886
Innate Immune System R-HSA-168249
Prolactin receptor signaling R-HSA-1170546
Cell surface interactions at the vascular wall R-HSA-202733
FRS-mediated FGFR4 signaling R-HSA-5654712
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
PI3K/AKT Signaling in Cancer R-HSA-2219528
Immune System R-HSA-168256
PI3K Cascade R-HSA-109704
Signal Transduction R-HSA-162582
MyD88-independent TLR4 cascade R-HSA-166166
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR1 R-HSA-5654736
MAPK1 (ERK2) activation R-HSA-112411
PD-1 signaling R-HSA-389948
Downstream signal transduction R-HSA-186763
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by CSF3 (G-CSF) R-HSA-9674555
Axon guidance R-HSA-422475
Infectious disease R-HSA-5663205
Netrin mediated repulsion signals R-HSA-418886
Signaling by FGFR3 R-HSA-5654741
Generic Transcription Pathway R-HSA-212436
Interleukin-6 signaling R-HSA-1059683
Platelet activation, signaling and aggregation R-HSA-76002
FLT3 Signaling R-HSA-9607240
Signaling by FGFR R-HSA-190236
PI-3K cascade:FGFR3 R-HSA-5654710
Signaling by NTRKs R-HSA-166520
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI-3K cascade:FGFR1 R-HSA-5654689
Transcriptional regulation by RUNX1 R-HSA-8878171
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Tie2 Signaling R-HSA-210993
GAB1 signalosome R-HSA-180292
PI-3K cascade:FGFR2 R-HSA-5654695
FLT3 signaling in disease R-HSA-9682385
Signaling by SCF-KIT R-HSA-1433557
Insulin receptor signalling cascade R-HSA-74751
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
RNA Polymerase II Transcription R-HSA-73857
Signaling by EGFR R-HSA-177929
FRS-mediated FGFR1 signaling R-HSA-5654693
Signaling by FGFR4 R-HSA-5654743
Innate Immune System R-HSA-168249
MET activates PTPN11 R-HSA-8865999
Adaptive Immune System R-HSA-1280218
IRS-mediated signalling R-HSA-112399
Interferon alpha/beta signaling R-HSA-909733
Nervous system development R-HSA-9675108
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling of activated FGFR3 R-HSA-5654708
Platelet homeostasis R-HSA-418346
GPVI-mediated activation cascade R-HSA-114604
Interferon Signaling R-HSA-913531
Signaling by MET R-HSA-6806834
Gene expression (Transcription) R-HSA-74160
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal regulatory protein family interactions R-HSA-391160
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
SARS-CoV Infections R-HSA-9679506
Cell-Cell communication R-HSA-1500931
CTLA4 inhibitory signaling R-HSA-389513
Negative regulation of FGFR1 signaling R-HSA-5654726
Interferon gamma signaling R-HSA-877300
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Regulation of IFNG signaling R-HSA-877312
Interleukin-20 family signaling R-HSA-8854691
Negative regulation of FGFR3 signaling R-HSA-5654732
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
PECAM1 interactions R-HSA-210990
Costimulation by the CD28 family R-HSA-388841
Negative regulation of FGFR2 signaling R-HSA-5654727
IGF1R signaling cascade R-HSA-2428924
Cytokine Signaling in Immune system R-HSA-1280215
RAF-independent MAPK1/3 activation R-HSA-112409
MAPK3 (ERK1) activation R-HSA-110056
Downstream signaling of activated FGFR1 R-HSA-5654687
STAT5 Activation R-HSA-9645135
Disease R-HSA-1643685
RET signaling R-HSA-8853659
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Signaling by Interleukins R-HSA-449147
Toll-like Receptor Cascades R-HSA-168898
Signaling by Leptin R-HSA-2586552
PIP3 activates AKT signaling R-HSA-1257604
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Platelet sensitization by LDL R-HSA-432142
Regulation of IFNA/IFNB signaling R-HSA-912694
Hemostasis R-HSA-109582
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by FGFR2 R-HSA-5654738
Developmental Biology R-HSA-1266738
Interleukin-6 family signaling R-HSA-6783589
Signaling by Insulin receptor R-HSA-74752
FRS-mediated FGFR3 signaling R-HSA-5654706
Netrin-1 signaling R-HSA-373752
SARS-CoV-2 Infection R-HSA-9694516
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by NTRK2 (TRKB) R-HSA-9006115
Interleukin-37 signaling R-HSA-9008059
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by PDGF R-HSA-186797
Interleukin-1 family signaling R-HSA-446652
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Downstream signaling of activated FGFR4 R-HSA-5654716
FRS-mediated FGFR2 signaling R-HSA-5654700
MAPK family signaling cascades R-HSA-5683057
PI-3K cascade:FGFR4 R-HSA-5654720

Expression Atlas ENSG00000179295
LRG display in Ensembl gene LRG_614
NCBI gene (formerly Entrezgene) 5781
GeneCards 9644
HGNC Symbol HGNC:9644
MIM gene 176876
MIM morbid 607785
UniProtKB Gene Name Q06124
WikiGene 5781
Gene: INPP5D
Ensembl ID : ENSG00000168918
Description: inositol polyphosphate-5-phosphatase D
Gene Synonyms: HP51CN,SHIP,SHIP1
1 APIs:
214 Possible Orthologues:

Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Phospholipid metabolism R-HSA-1483257
Interleukin receptor SHC signaling R-HSA-912526
Hemostasis R-HSA-109582
TCR signaling R-HSA-202403
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by Interleukins R-HSA-449147
Cell surface interactions at the vascular wall R-HSA-202733
Metabolism R-HSA-1430728
Inositol phosphate metabolism R-HSA-1483249
Interleukin-2 family signaling R-HSA-451927
Cytokine Signaling in Immune system R-HSA-1280215
PECAM1 interactions R-HSA-210990
PI Metabolism R-HSA-1483255
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Metabolism of lipids R-HSA-556833
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Downstream TCR signaling R-HSA-202424
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Phospholipid metabolism R-HSA-1483257
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Metabolism of lipids R-HSA-556833
Immune System R-HSA-168256
Metabolism R-HSA-1430728
Interleukin-2 family signaling R-HSA-451927
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PECAM1 interactions R-HSA-210990
PI Metabolism R-HSA-1483255
Interleukin receptor SHC signaling R-HSA-912526
TCR signaling R-HSA-202403
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Adaptive Immune System R-HSA-1280218
Downstream TCR signaling R-HSA-202424
Cell surface interactions at the vascular wall R-HSA-202733
Inositol phosphate metabolism R-HSA-1483249
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Hemostasis R-HSA-109582
Hemostasis R-HSA-109582
Cell surface interactions at the vascular wall R-HSA-202733
TCR signaling R-HSA-202403
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Inositol phosphate metabolism R-HSA-1483249
Interleukin-2 family signaling R-HSA-451927
Adaptive Immune System R-HSA-1280218
Interleukin receptor SHC signaling R-HSA-912526
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Cytokine Signaling in Immune system R-HSA-1280215
PI Metabolism R-HSA-1483255
PECAM1 interactions R-HSA-210990
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Signaling by Interleukins R-HSA-449147
Downstream TCR signaling R-HSA-202424
Immune System R-HSA-168256
Phospholipid metabolism R-HSA-1483257
PECAM1 interactions R-HSA-210990
Interleukin-2 family signaling R-HSA-451927
Cytokine Signaling in Immune system R-HSA-1280215
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
Hemostasis R-HSA-109582
Metabolism R-HSA-1430728
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Immune System R-HSA-168256
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Adaptive Immune System R-HSA-1280218
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Phospholipid metabolism R-HSA-1483257
Signaling by Interleukins R-HSA-449147
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Inositol phosphate metabolism R-HSA-1483249
Metabolism of lipids R-HSA-556833
Interleukin receptor SHC signaling R-HSA-912526
Cell surface interactions at the vascular wall R-HSA-202733
PI Metabolism R-HSA-1483255
Cell surface interactions at the vascular wall R-HSA-202733
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PECAM1 interactions R-HSA-210990
Interleukin-2 family signaling R-HSA-451927
PI Metabolism R-HSA-1483255
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
TCR signaling R-HSA-202403
Immune System R-HSA-168256
Phospholipid metabolism R-HSA-1483257
Hemostasis R-HSA-109582
Interleukin receptor SHC signaling R-HSA-912526
Metabolism of lipids R-HSA-556833
Inositol phosphate metabolism R-HSA-1483249
Downstream TCR signaling R-HSA-202424
Metabolism R-HSA-1430728
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Adaptive Immune System R-HSA-1280218
Signaling by Interleukins R-HSA-449147
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Cytokine Signaling in Immune system R-HSA-1280215
Hemostasis R-HSA-109582
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by Interleukins R-HSA-449147
Metabolism of lipids R-HSA-556833
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
PECAM1 interactions R-HSA-210990
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Immune System R-HSA-168256
Metabolism R-HSA-1430728
Interleukin receptor SHC signaling R-HSA-912526
Cell surface interactions at the vascular wall R-HSA-202733
Downstream TCR signaling R-HSA-202424
Adaptive Immune System R-HSA-1280218
TCR signaling R-HSA-202403
PI Metabolism R-HSA-1483255
Phospholipid metabolism R-HSA-1483257
Interleukin-2 family signaling R-HSA-451927
Inositol phosphate metabolism R-HSA-1483249
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-2 family signaling R-HSA-451927
Interleukin receptor SHC signaling R-HSA-912526
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Adaptive Immune System R-HSA-1280218
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Immune System R-HSA-168256
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Inositol phosphate metabolism R-HSA-1483249
Hemostasis R-HSA-109582
Cell surface interactions at the vascular wall R-HSA-202733
Cytokine Signaling in Immune system R-HSA-1280215
PI Metabolism R-HSA-1483255
Phospholipid metabolism R-HSA-1483257
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
PECAM1 interactions R-HSA-210990
Signaling by Interleukins R-HSA-449147
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
PECAM1 interactions R-HSA-210990
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-2 family signaling R-HSA-451927
Adaptive Immune System R-HSA-1280218
Interleukin receptor SHC signaling R-HSA-912526
Cell surface interactions at the vascular wall R-HSA-202733
TCR signaling R-HSA-202403
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Inositol phosphate metabolism R-HSA-1483249
Downstream TCR signaling R-HSA-202424
Metabolism of lipids R-HSA-556833
Phospholipid metabolism R-HSA-1483257
Metabolism R-HSA-1430728
Immune System R-HSA-168256
PI Metabolism R-HSA-1483255
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Hemostasis R-HSA-109582
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Signaling by Interleukins R-HSA-449147
Interleukin-2 family signaling R-HSA-451927
TCR signaling R-HSA-202403
Cytokine Signaling in Immune system R-HSA-1280215
Downstream TCR signaling R-HSA-202424
Immune System R-HSA-168256
Phospholipid metabolism R-HSA-1483257
PI Metabolism R-HSA-1483255
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by Interleukins R-HSA-449147
Cell surface interactions at the vascular wall R-HSA-202733
PECAM1 interactions R-HSA-210990
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Metabolism R-HSA-1430728
Interleukin receptor SHC signaling R-HSA-912526
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Metabolism of lipids R-HSA-556833
Hemostasis R-HSA-109582
Inositol phosphate metabolism R-HSA-1483249
Adaptive Immune System R-HSA-1280218
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
PECAM1 interactions R-HSA-210990
TCR signaling R-HSA-202403
Interleukin-2 family signaling R-HSA-451927
Downstream TCR signaling R-HSA-202424
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by Interleukins R-HSA-449147
Metabolism of lipids R-HSA-556833
Adaptive Immune System R-HSA-1280218
Hemostasis R-HSA-109582
Metabolism R-HSA-1430728
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Immune System R-HSA-168256
Phospholipid metabolism R-HSA-1483257
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin receptor SHC signaling R-HSA-912526
PI Metabolism R-HSA-1483255
Inositol phosphate metabolism R-HSA-1483249
Synthesis of PIPs at the plasma membrane R-HSA-1660499

Expression Atlas ENSG00000168918
NCBI gene (formerly Entrezgene) 3635
GeneCards 6079
HGNC Symbol HGNC:6079
MIM gene 601582
UniProtKB Gene Name Q92835
WikiGene 3635
Gene: NT5E
Ensembl ID : ENSG00000135318
Description: 5'-nucleotidase ecto
Gene Synonyms: CALJA,CD73,EN,ENT,NT5
1 APIs:
250 Possible Orthologues:

Nucleotide catabolism R-HSA-8956319
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Infectious disease R-HSA-5663205
Metabolism of vitamins and cofactors R-HSA-196854
Purine catabolism R-HSA-74259
Nicotinate metabolism R-HSA-196807
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Leishmania infection R-HSA-9658195
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Disease R-HSA-1643685
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Pyrimidine catabolism R-HSA-73621
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Purine catabolism R-HSA-74259
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Nucleotide catabolism R-HSA-8956319
Leishmania infection R-HSA-9658195
Disease R-HSA-1643685
Metabolism of vitamins and cofactors R-HSA-196854
Nicotinate metabolism R-HSA-196807
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Infectious disease R-HSA-5663205
Infectious disease R-HSA-5663205
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Purine catabolism R-HSA-74259
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Nicotinate metabolism R-HSA-196807
Nucleotide catabolism R-HSA-8956319
Metabolism of vitamins and cofactors R-HSA-196854
Leishmania infection R-HSA-9658195
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Disease R-HSA-1643685
Pyrimidine catabolism R-HSA-73621
Leishmania infection R-HSA-9658195
Infectious disease R-HSA-5663205
Metabolism of nucleotides R-HSA-15869
Metabolism of vitamins and cofactors R-HSA-196854
Purine catabolism R-HSA-74259
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Metabolism R-HSA-1430728
Nicotinate metabolism R-HSA-196807
Pyrimidine catabolism R-HSA-73621
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Nucleotide catabolism R-HSA-8956319
Disease R-HSA-1643685
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Purine catabolism R-HSA-74259
Metabolism of vitamins and cofactors R-HSA-196854
Pyrimidine catabolism R-HSA-73621
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Nicotinate metabolism R-HSA-196807
Leishmania infection R-HSA-9658195
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Nucleotide catabolism R-HSA-8956319
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Disease R-HSA-1643685
Pyrimidine catabolism R-HSA-73621
Metabolism of nucleotides R-HSA-15869
Leishmania infection R-HSA-9658195
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Infectious disease R-HSA-5663205
Nicotinate metabolism R-HSA-196807
Metabolism of vitamins and cofactors R-HSA-196854
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Purine catabolism R-HSA-74259
Metabolism R-HSA-1430728
Metabolism of vitamins and cofactors R-HSA-196854
Infectious disease R-HSA-5663205
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Leishmania infection R-HSA-9658195
Purine catabolism R-HSA-74259
Pyrimidine catabolism R-HSA-73621
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Nicotinate metabolism R-HSA-196807
Nucleotide catabolism R-HSA-8956319
Disease R-HSA-1643685
Metabolism of nucleotides R-HSA-15869
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Leishmania infection R-HSA-9658195
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Nicotinate metabolism R-HSA-196807
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of nucleotides R-HSA-15869
Purine catabolism R-HSA-74259
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Nucleotide catabolism R-HSA-8956319
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Infectious disease R-HSA-5663205
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Pyrimidine catabolism R-HSA-73621
Purine catabolism R-HSA-74259
Leishmania infection R-HSA-9658195
Metabolism of vitamins and cofactors R-HSA-196854
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Disease R-HSA-1643685
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Nicotinate metabolism R-HSA-196807
Metabolism R-HSA-1430728
Pyrimidine catabolism R-HSA-73621
Infectious disease R-HSA-5663205
Purine catabolism R-HSA-74259
Metabolism of vitamins and cofactors R-HSA-196854
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Nicotinate metabolism R-HSA-196807
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Leishmania infection R-HSA-9658195
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Metabolism of nucleotides R-HSA-15869
Disease R-HSA-1643685
Nucleotide catabolism R-HSA-8956319
Metabolism of vitamins and cofactors R-HSA-196854
Nicotinate metabolism R-HSA-196807
Nucleotide catabolism R-HSA-8956319
Infectious disease R-HSA-5663205
Purine catabolism R-HSA-74259
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Pyrimidine catabolism R-HSA-73621
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Leishmania infection R-HSA-9658195

Expression Atlas ENSG00000135318
NCBI gene (formerly Entrezgene) 4907
GeneCards 8021
HGNC Symbol HGNC:8021
MIM gene 129190
MIM morbid 211800
UniProtKB Gene Name Q96B60
WikiGene 4907
Gene: PPP3CA
Ensembl ID : ENSG00000138814
Description: protein phosphatase 3 catalytic subunit alpha
Gene Synonyms: CALN,CALNA,CNA1,PPP2B
1 APIs:
230 Possible Orthologues:

GPCR downstream signalling R-HSA-388396
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Ca2+ pathway R-HSA-4086398
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Calcineurin activates NFAT R-HSA-2025928
C-type lectin receptors (CLRs) R-HSA-5621481
CLEC7A (Dectin-1) signaling R-HSA-5607764
FCERI mediated Ca+2 mobilization R-HSA-2871809
DARPP-32 events R-HSA-180024
Beta-catenin independent WNT signaling R-HSA-3858494
Opioid Signalling R-HSA-111885
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Adaptive Immune System R-HSA-1280218
G alpha (i) signalling events R-HSA-418594
Signaling by WNT R-HSA-195721
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ca2+ pathway R-HSA-4086398
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by GPCR R-HSA-372790
FCERI mediated Ca+2 mobilization R-HSA-2871809
Signal Transduction R-HSA-162582
DARPP-32 events R-HSA-180024
G alpha (i) signalling events R-HSA-418594
Opioid Signalling R-HSA-111885
GPCR downstream signalling R-HSA-388396
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Calcineurin activates NFAT R-HSA-2025928
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by WNT R-HSA-195721
C-type lectin receptors (CLRs) R-HSA-5621481
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by the B Cell Receptor (BCR) R-HSA-983705
CLEC7A (Dectin-1) signaling R-HSA-5607764
C-type lectin receptors (CLRs) R-HSA-5621481
Adaptive Immune System R-HSA-1280218
Signaling by WNT R-HSA-195721
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Immune System R-HSA-168256
Beta-catenin independent WNT signaling R-HSA-3858494
Innate Immune System R-HSA-168249
Ca2+ pathway R-HSA-4086398
DARPP-32 events R-HSA-180024
Opioid Signalling R-HSA-111885
Signal Transduction R-HSA-162582
Calcineurin activates NFAT R-HSA-2025928
G alpha (i) signalling events R-HSA-418594
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated Ca+2 mobilization R-HSA-2871809
Beta-catenin independent WNT signaling R-HSA-3858494
Immune System R-HSA-168256
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
DARPP-32 events R-HSA-180024
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Opioid Signalling R-HSA-111885
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ca2+ pathway R-HSA-4086398
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
Calcineurin activates NFAT R-HSA-2025928
Signaling by WNT R-HSA-195721
CLEC7A (Dectin-1) signaling R-HSA-5607764
C-type lectin receptors (CLRs) R-HSA-5621481
FCERI mediated Ca+2 mobilization R-HSA-2871809
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by GPCR R-HSA-372790
Beta-catenin independent WNT signaling R-HSA-3858494
Opioid Signalling R-HSA-111885
Ca2+ pathway R-HSA-4086398
Signal Transduction R-HSA-162582
DARPP-32 events R-HSA-180024
G alpha (i) signalling events R-HSA-418594
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
GPCR downstream signalling R-HSA-388396
FCERI mediated Ca+2 mobilization R-HSA-2871809
Calcineurin activates NFAT R-HSA-2025928
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by WNT R-HSA-195721
Immune System R-HSA-168256
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by WNT R-HSA-195721
CLEC7A (Dectin-1) signaling R-HSA-5607764
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Immune System R-HSA-168256
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
FCERI mediated Ca+2 mobilization R-HSA-2871809
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by GPCR R-HSA-372790
Innate Immune System R-HSA-168249
DARPP-32 events R-HSA-180024
C-type lectin receptors (CLRs) R-HSA-5621481
Ca2+ pathway R-HSA-4086398
Signaling by the B Cell Receptor (BCR) R-HSA-983705
GPCR downstream signalling R-HSA-388396
Beta-catenin independent WNT signaling R-HSA-3858494
Calcineurin activates NFAT R-HSA-2025928
Opioid Signalling R-HSA-111885
Adaptive Immune System R-HSA-1280218
Ca2+ pathway R-HSA-4086398
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Opioid Signalling R-HSA-111885
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
FCERI mediated Ca+2 mobilization R-HSA-2871809
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Calcineurin activates NFAT R-HSA-2025928
Signaling by WNT R-HSA-195721
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Innate Immune System R-HSA-168249
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Beta-catenin independent WNT signaling R-HSA-3858494
DARPP-32 events R-HSA-180024
GPCR downstream signalling R-HSA-388396
Ca2+ pathway R-HSA-4086398
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
G alpha (i) signalling events R-HSA-418594
Immune System R-HSA-168256
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Opioid Signalling R-HSA-111885
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FCERI mediated Ca+2 mobilization R-HSA-2871809
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
GPCR downstream signalling R-HSA-388396
Adaptive Immune System R-HSA-1280218
Calcineurin activates NFAT R-HSA-2025928
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
C-type lectin receptors (CLRs) R-HSA-5621481
Beta-catenin independent WNT signaling R-HSA-3858494
DARPP-32 events R-HSA-180024
Signaling by WNT R-HSA-195721
Opioid Signalling R-HSA-111885
FCERI mediated Ca+2 mobilization R-HSA-2871809
Signal Transduction R-HSA-162582
Signaling by the B Cell Receptor (BCR) R-HSA-983705
C-type lectin receptors (CLRs) R-HSA-5621481
Beta-catenin independent WNT signaling R-HSA-3858494
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by GPCR R-HSA-372790
Signaling by WNT R-HSA-195721
DARPP-32 events R-HSA-180024
Immune System R-HSA-168256
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
CLEC7A (Dectin-1) signaling R-HSA-5607764
Calcineurin activates NFAT R-HSA-2025928
Innate Immune System R-HSA-168249
Ca2+ pathway R-HSA-4086398
Adaptive Immune System R-HSA-1280218
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
C-type lectin receptors (CLRs) R-HSA-5621481
Adaptive Immune System R-HSA-1280218
FCERI mediated Ca+2 mobilization R-HSA-2871809
DARPP-32 events R-HSA-180024
Signaling by WNT R-HSA-195721
Ca2+ pathway R-HSA-4086398
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signal Transduction R-HSA-162582
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
CLEC7A (Dectin-1) signaling R-HSA-5607764
Beta-catenin independent WNT signaling R-HSA-3858494
Immune System R-HSA-168256
Signaling by GPCR R-HSA-372790
Calcineurin activates NFAT R-HSA-2025928
Opioid Signalling R-HSA-111885
G alpha (i) signalling events R-HSA-418594
Innate Immune System R-HSA-168249
GPCR downstream signalling R-HSA-388396

Expression Atlas ENSG00000138814
NCBI gene (formerly Entrezgene) 5530
GeneCards 9314
HGNC Symbol HGNC:9314
MIM gene 114105
MIM morbid 618265
UniProtKB Gene Name Q08209
WikiGene 5530
Gene: PTPRB
Ensembl ID : ENSG00000127329
Description: protein tyrosine phosphatase receptor type B
Gene Synonyms: PTPB
1 APIs:
268 Possible Orthologues:

Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249

Expression Atlas ENSG00000127329
NCBI gene (formerly Entrezgene) 5787
GeneCards 9665
HGNC Symbol HGNC:9665
MIM gene 176882
UniProtKB Gene Name Q6ZR19
WikiGene 5787
Gene: PDE4D
Ensembl ID : ENSG00000113448
Description: phosphodiesterase 4D
Gene Synonyms: DPDE3
24 APIs:
235 Possible Orthologues:

Signaling by GPCR R-HSA-372790
Opioid Signalling R-HSA-111885
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
DARPP-32 events R-HSA-180024
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
DARPP-32 events R-HSA-180024
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Opioid Signalling R-HSA-111885
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
G alpha (i) signalling events R-HSA-418594
DARPP-32 events R-HSA-180024
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Opioid Signalling R-HSA-111885
GPCR downstream signalling R-HSA-388396
Opioid Signalling R-HSA-111885
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
DARPP-32 events R-HSA-180024
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
DARPP-32 events R-HSA-180024
Opioid Signalling R-HSA-111885
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
G alpha (i) signalling events R-HSA-418594
Opioid Signalling R-HSA-111885
Signaling by GPCR R-HSA-372790
DARPP-32 events R-HSA-180024
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
DARPP-32 events R-HSA-180024
Signaling by GPCR R-HSA-372790
Opioid Signalling R-HSA-111885
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
DARPP-32 events R-HSA-180024
Opioid Signalling R-HSA-111885
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
DARPP-32 events R-HSA-180024
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
Opioid Signalling R-HSA-111885
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Opioid Signalling R-HSA-111885
GPCR downstream signalling R-HSA-388396
DARPP-32 events R-HSA-180024
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000113448
NCBI gene (formerly Entrezgene) 5144
GeneCards 8783
HGNC Symbol HGNC:8783
MIM gene 600129
MIM morbid 614613
UniProtKB Gene Name Q08499
WikiGene 5144