Gene: DHFR
Ensembl ID : ENSG00000228716
Description: dihydrofolate reductase
Gene Synonyms: DHFR1
5 APIs:
316 Possible Orthologues:

Cell Cycle, Mitotic R-HSA-69278
Metabolism R-HSA-1430728
Metabolism of cofactors R-HSA-8978934
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
G1/S Transition R-HSA-69206
Metabolism of vitamins and cofactors R-HSA-196854
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
G1/S-Specific Transcription R-HSA-69205
Metabolism of folate and pterines R-HSA-196757
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of folate and pterines R-HSA-196757
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
G1/S-Specific Transcription R-HSA-69205
Metabolism of cofactors R-HSA-8978934
Metabolism R-HSA-1430728
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism R-HSA-1430728
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Cell Cycle, Mitotic R-HSA-69278
G1/S-Specific Transcription R-HSA-69205
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of folate and pterines R-HSA-196757
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of cofactors R-HSA-8978934
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Cell Cycle, Mitotic R-HSA-69278
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism R-HSA-1430728
G1/S Transition R-HSA-69206
Metabolism of cofactors R-HSA-8978934
Metabolism of folate and pterines R-HSA-196757
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S-Specific Transcription R-HSA-69205
Cell Cycle R-HSA-1640170
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Cell Cycle R-HSA-1640170
Metabolism of folate and pterines R-HSA-196757
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Cell Cycle, Mitotic R-HSA-69278
Metabolism of cofactors R-HSA-8978934
G1/S-Specific Transcription R-HSA-69205
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism R-HSA-1430728
Metabolism of vitamins and cofactors R-HSA-196854
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
Metabolism of vitamins and cofactors R-HSA-196854
Cell Cycle, Mitotic R-HSA-69278
Metabolism of folate and pterines R-HSA-196757
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S-Specific Transcription R-HSA-69205
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
G1/S Transition R-HSA-69206
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Metabolism of cofactors R-HSA-8978934
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
Cell Cycle, Mitotic R-HSA-69278
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
G1/S Transition R-HSA-69206
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of folate and pterines R-HSA-196757
Metabolism of vitamins and cofactors R-HSA-196854
G1/S-Specific Transcription R-HSA-69205
Metabolism of cofactors R-HSA-8978934
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of cofactors R-HSA-8978934
Metabolism of folate and pterines R-HSA-196757
Cell Cycle, Mitotic R-HSA-69278
Metabolism of vitamins and cofactors R-HSA-196854
G1/S-Specific Transcription R-HSA-69205
G1/S Transition R-HSA-69206
Metabolism R-HSA-1430728
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Cell Cycle R-HSA-1640170

Expression Atlas ENSG00000228716
NCBI gene (formerly Entrezgene) 1719
GeneCards 2861
HGNC Symbol HGNC:2861
MIM gene 126060
MIM morbid 613839
UniProtKB Gene Name P00374
WikiGene 1719
Gene: ALOX5
Ensembl ID : ENSG00000012779
Description: arachidonate 5-lipoxygenase
Gene Synonyms: 5-LOX
8 APIs:
223 Possible Orthologues:

Synthesis of Lipoxins (LX) R-HSA-2142700
Metabolism of lipids R-HSA-556833
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Cytokine Signaling in Immune system R-HSA-1280215
Fatty acid metabolism R-HSA-8978868
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Metabolism R-HSA-1430728
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Immune System R-HSA-168256
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of DPAn-3-derived maresins R-HSA-9026290
Neutrophil degranulation R-HSA-6798695
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Biosynthesis of maresins R-HSA-9018682
Biosynthesis of DPAn-3-derived protectins and resolvins R-HSA-9026286
Biosynthesis of D-series resolvins R-HSA-9018676
Innate Immune System R-HSA-168249
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Interleukin-1 family signaling R-HSA-446652
Interleukin-18 signaling R-HSA-9012546
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Biosynthesis of DPAn-3-derived 13-series resolvins R-HSA-9026403
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Signaling by Interleukins R-HSA-449147
Metabolism R-HSA-1430728
Interleukin-18 signaling R-HSA-9012546
Interleukin-1 family signaling R-HSA-446652
Biosynthesis of DPAn-3-derived maresins R-HSA-9026290
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Biosynthesis of D-series resolvins R-HSA-9018676
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Cytokine Signaling in Immune system R-HSA-1280215
Fatty acid metabolism R-HSA-8978868
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Immune System R-HSA-168256
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Biosynthesis of DPAn-3-derived protectins and resolvins R-HSA-9026286
Biosynthesis of DPAn-3-derived 13-series resolvins R-HSA-9026403
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688
Synthesis of Lipoxins (LX) R-HSA-2142700
Metabolism of lipids R-HSA-556833
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Signaling by Interleukins R-HSA-449147
Biosynthesis of maresins R-HSA-9018682
Fatty acid metabolism R-HSA-8978868
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Synthesis of Lipoxins (LX) R-HSA-2142700
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Innate Immune System R-HSA-168249
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688
Biosynthesis of DPAn-3-derived maresins R-HSA-9026290
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Signaling by Interleukins R-HSA-449147
Metabolism R-HSA-1430728
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Biosynthesis of DPAn-3-derived protectins and resolvins R-HSA-9026286
Interleukin-18 signaling R-HSA-9012546
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Biosynthesis of maresins R-HSA-9018682
Immune System R-HSA-168256
Interleukin-1 family signaling R-HSA-446652
Biosynthesis of D-series resolvins R-HSA-9018676
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Arachidonic acid metabolism R-HSA-2142753
Metabolism of lipids R-HSA-556833
Neutrophil degranulation R-HSA-6798695
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Biosynthesis of DPAn-3-derived 13-series resolvins R-HSA-9026403
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Metabolism of lipids R-HSA-556833
Biosynthesis of D-series resolvins R-HSA-9018676
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Innate Immune System R-HSA-168249
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Interleukin-1 family signaling R-HSA-446652
Biosynthesis of DPAn-3-derived protectins and resolvins R-HSA-9026286
Interleukin-18 signaling R-HSA-9012546
Synthesis of Lipoxins (LX) R-HSA-2142700
Biosynthesis of DPAn-3-derived 13-series resolvins R-HSA-9026403
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Fatty acid metabolism R-HSA-8978868
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Neutrophil degranulation R-HSA-6798695
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of DPAn-3-derived maresins R-HSA-9026290
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Immune System R-HSA-168256
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Biosynthesis of maresins R-HSA-9018682
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Biosynthesis of DPAn-3-derived maresins R-HSA-9026290
Innate Immune System R-HSA-168249
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Signaling by Interleukins R-HSA-449147
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of DPAn-3-derived protectins and resolvins R-HSA-9026286
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Neutrophil degranulation R-HSA-6798695
Metabolism R-HSA-1430728
Biosynthesis of maresins R-HSA-9018682
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Interleukin-1 family signaling R-HSA-446652
Immune System R-HSA-168256
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688
Metabolism of lipids R-HSA-556833
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Synthesis of Lipoxins (LX) R-HSA-2142700
Biosynthesis of D-series resolvins R-HSA-9018676
Cytokine Signaling in Immune system R-HSA-1280215
Biosynthesis of DPAn-3-derived 13-series resolvins R-HSA-9026403
Fatty acid metabolism R-HSA-8978868
Interleukin-18 signaling R-HSA-9012546
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Arachidonic acid metabolism R-HSA-2142753
Cytokine Signaling in Immune system R-HSA-1280215
Biosynthesis of DPAn-3-derived 13-series resolvins R-HSA-9026403
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688
Neutrophil degranulation R-HSA-6798695
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Innate Immune System R-HSA-168249
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Signaling by Interleukins R-HSA-449147
Interleukin-1 family signaling R-HSA-446652
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Biosynthesis of D-series resolvins R-HSA-9018676
Biosynthesis of DPAn-3-derived maresins R-HSA-9026290
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Interleukin-18 signaling R-HSA-9012546
Biosynthesis of maresins R-HSA-9018682
Immune System R-HSA-168256
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Fatty acid metabolism R-HSA-8978868
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of DPAn-3-derived protectins and resolvins R-HSA-9026286
Synthesis of Lipoxins (LX) R-HSA-2142700
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Metabolism R-HSA-1430728
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of DPAn-3-derived 13-series resolvins R-HSA-9026403
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Signaling by Interleukins R-HSA-449147
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688
Biosynthesis of maresins R-HSA-9018682
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Synthesis of Lipoxins (LX) R-HSA-2142700
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Biosynthesis of DPAn-3-derived maresins R-HSA-9026290
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Cytokine Signaling in Immune system R-HSA-1280215
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Interleukin-18 signaling R-HSA-9012546
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
Biosynthesis of D-series resolvins R-HSA-9018676
Fatty acid metabolism R-HSA-8978868
Biosynthesis of DPAn-3-derived protectins and resolvins R-HSA-9026286
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Metabolism of lipids R-HSA-556833
Biosynthesis of maresins R-HSA-9018682
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Arachidonic acid metabolism R-HSA-2142753
Interleukin-18 signaling R-HSA-9012546
Interleukin-1 family signaling R-HSA-446652
Metabolism of lipids R-HSA-556833
Biosynthesis of DPAn-3-derived maresins R-HSA-9026290
Biosynthesis of DPAn-3-derived protectins and resolvins R-HSA-9026286
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Biosynthesis of D-series resolvins R-HSA-9018676
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Innate Immune System R-HSA-168249
Synthesis of Lipoxins (LX) R-HSA-2142700
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Neutrophil degranulation R-HSA-6798695
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Biosynthesis of DPAn-3-derived 13-series resolvins R-HSA-9026403
Metabolism R-HSA-1430728
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Fatty acid metabolism R-HSA-8978868
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688
Immune System R-HSA-168256
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688
Interleukin-18 signaling R-HSA-9012546
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
Biosynthesis of DPAn-3-derived protectins and resolvins R-HSA-9026286
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Fatty acid metabolism R-HSA-8978868
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Synthesis of Lipoxins (LX) R-HSA-2142700
Biosynthesis of DPAn-3-derived maresins R-HSA-9026290
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Immune System R-HSA-168256
Biosynthesis of D-series resolvins R-HSA-9018676
Metabolism of lipids R-HSA-556833
Neutrophil degranulation R-HSA-6798695
Signaling by Interleukins R-HSA-449147
Arachidonic acid metabolism R-HSA-2142753
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Biosynthesis of maresins R-HSA-9018682
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Biosynthesis of DPAn-3-derived 13-series resolvins R-HSA-9026403
Metabolism R-HSA-1430728
Biosynthesis of DPA-derived SPMs R-HSA-9018683
Synthesis of Lipoxins (LX) R-HSA-2142700
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661
Biosynthesis of DPAn-3-derived maresins R-HSA-9026290
Metabolism of lipids R-HSA-556833
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Biosynthesis of DPAn-3 SPMs R-HSA-9025094
Biosynthesis of maresins R-HSA-9018682
Metabolism R-HSA-1430728
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896
Biosynthesis of EPA-derived SPMs R-HSA-9018679
Interleukin-1 family signaling R-HSA-446652
Biosynthesis of DPAn-3-derived 13-series resolvins R-HSA-9026403
Fatty acid metabolism R-HSA-8978868
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of D-series resolvins R-HSA-9018676
Immune System R-HSA-168256
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688
Biosynthesis of DPAn-3-derived protectins and resolvins R-HSA-9026286
Interleukin-18 signaling R-HSA-9012546
Signaling by Interleukins R-HSA-449147
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678

Expression Atlas ENSG00000012779
NCBI gene (formerly Entrezgene) 240
GeneCards 435
HGNC Symbol HGNC:435
MIM gene 152390
MIM morbid 600807
UniProtKB Gene Name P09917
WikiGene 240
Gene: IDO1
Ensembl ID : ENSG00000131203
Description: indoleamine 2,3-dioxygenase 1
Gene Synonyms: IDO,INDO
2 APIs:
98 Possible Orthologues:

Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
Tryptophan catabolism R-HSA-71240
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
Tryptophan catabolism R-HSA-71240
Metabolism of amino acids and derivatives R-HSA-71291
Tryptophan catabolism R-HSA-71240
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Tryptophan catabolism R-HSA-71240
Tryptophan catabolism R-HSA-71240
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of amino acids and derivatives R-HSA-71291
Tryptophan catabolism R-HSA-71240
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Tryptophan catabolism R-HSA-71240
Metabolism R-HSA-1430728

Expression Atlas ENSG00000131203
NCBI gene (formerly Entrezgene) 3620
GeneCards 6059
HGNC Symbol HGNC:6059
MIM gene 147435
UniProtKB Gene Name P14902
WikiGene 3620
Gene: PTGS1
Ensembl ID : ENSG00000095303
Description: prostaglandin-endoperoxide synthase 1
Gene Synonyms: COX1,PGHS-1,PTGHS
58 APIs:
256 Possible Orthologues:

COX reactions R-HSA-140180
Arachidonic acid metabolism R-HSA-2142753
Fatty acid metabolism R-HSA-8978868
Biological oxidations R-HSA-211859
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
COX reactions R-HSA-140180
Metabolism R-HSA-1430728
Fatty acid metabolism R-HSA-8978868
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Arachidonic acid metabolism R-HSA-2142753
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Metabolism of lipids R-HSA-556833
COX reactions R-HSA-140180
Fatty acid metabolism R-HSA-8978868
Phase I - Functionalization of compounds R-HSA-211945
Arachidonic acid metabolism R-HSA-2142753
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Arachidonic acid metabolism R-HSA-2142753
Metabolism of lipids R-HSA-556833
Phase I - Functionalization of compounds R-HSA-211945
Fatty acid metabolism R-HSA-8978868
COX reactions R-HSA-140180
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Arachidonic acid metabolism R-HSA-2142753
Metabolism of lipids R-HSA-556833
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
COX reactions R-HSA-140180
Fatty acid metabolism R-HSA-8978868
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Fatty acid metabolism R-HSA-8978868
Metabolism R-HSA-1430728
Arachidonic acid metabolism R-HSA-2142753
Biological oxidations R-HSA-211859
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Metabolism of lipids R-HSA-556833
COX reactions R-HSA-140180
Biological oxidations R-HSA-211859
Fatty acid metabolism R-HSA-8978868
Arachidonic acid metabolism R-HSA-2142753
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Metabolism R-HSA-1430728
COX reactions R-HSA-140180
Metabolism R-HSA-1430728
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Biological oxidations R-HSA-211859
Arachidonic acid metabolism R-HSA-2142753
Fatty acid metabolism R-HSA-8978868
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
COX reactions R-HSA-140180
Phase I - Functionalization of compounds R-HSA-211945
Arachidonic acid metabolism R-HSA-2142753
COX reactions R-HSA-140180
Metabolism of lipids R-HSA-556833
Fatty acid metabolism R-HSA-8978868
Biological oxidations R-HSA-211859
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Metabolism R-HSA-1430728
Fatty acid metabolism R-HSA-8978868
Biological oxidations R-HSA-211859
COX reactions R-HSA-140180
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Arachidonic acid metabolism R-HSA-2142753
Phase I - Functionalization of compounds R-HSA-211945
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123

Expression Atlas ENSG00000095303
LRG display in Ensembl gene LRG_639
NCBI gene (formerly Entrezgene) 5742
GeneCards 9604
HGNC Symbol HGNC:9604
MIM gene 176805
UniProtKB Gene Name X6RJD6
WikiGene 5742
Gene: HMGCR
Ensembl ID : ENSG00000113161
Description: 3-hydroxy-3-methylglutaryl-CoA reductase
Gene Synonyms:
10 APIs:
272 Possible Orthologues:

PPARA activates gene expression R-HSA-1989781
Cholesterol biosynthesis R-HSA-191273
Metabolism of steroids R-HSA-8957322
Nervous system development R-HSA-9675108
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Developmental Biology R-HSA-1266738
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Cholesterol biosynthesis R-HSA-191273
Developmental Biology R-HSA-1266738
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
PPARA activates gene expression R-HSA-1989781
Metabolism of steroids R-HSA-8957322
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Metabolism R-HSA-1430728
PPARA activates gene expression R-HSA-1989781
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Metabolism of lipids R-HSA-556833
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism of steroids R-HSA-8957322
Cholesterol biosynthesis R-HSA-191273
Nervous system development R-HSA-9675108
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
PPARA activates gene expression R-HSA-1989781
Developmental Biology R-HSA-1266738
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Metabolism of steroids R-HSA-8957322
Nervous system development R-HSA-9675108
Metabolism R-HSA-1430728
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Metabolism of lipids R-HSA-556833
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Cholesterol biosynthesis R-HSA-191273
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Metabolism R-HSA-1430728
Nervous system development R-HSA-9675108
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Developmental Biology R-HSA-1266738
PPARA activates gene expression R-HSA-1989781
Metabolism of lipids R-HSA-556833
Cholesterol biosynthesis R-HSA-191273
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
PPARA activates gene expression R-HSA-1989781
Metabolism of steroids R-HSA-8957322
Developmental Biology R-HSA-1266738
Cholesterol biosynthesis R-HSA-191273
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Nervous system development R-HSA-9675108
Metabolism of lipids R-HSA-556833
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Metabolism R-HSA-1430728
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Metabolism of lipids R-HSA-556833
Cholesterol biosynthesis R-HSA-191273
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
PPARA activates gene expression R-HSA-1989781
Metabolism of steroids R-HSA-8957322
Cholesterol biosynthesis R-HSA-191273
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism of steroids R-HSA-8957322
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Developmental Biology R-HSA-1266738
Metabolism of lipids R-HSA-556833
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Nervous system development R-HSA-9675108
Metabolism R-HSA-1430728
PPARA activates gene expression R-HSA-1989781
Metabolism of steroids R-HSA-8957322
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Nervous system development R-HSA-9675108
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism R-HSA-1430728
Cholesterol biosynthesis R-HSA-191273
PPARA activates gene expression R-HSA-1989781
Metabolism of lipids R-HSA-556833
Developmental Biology R-HSA-1266738
Metabolism of lipids R-HSA-556833
Developmental Biology R-HSA-1266738
Metabolism R-HSA-1430728
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
PPARA activates gene expression R-HSA-1989781
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Cholesterol biosynthesis R-HSA-191273
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Nervous system development R-HSA-9675108
Metabolism of steroids R-HSA-8957322
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Metabolism of steroids R-HSA-8957322
Nervous system development R-HSA-9675108
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism R-HSA-1430728
PPARA activates gene expression R-HSA-1989781
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Developmental Biology R-HSA-1266738
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Metabolism of lipids R-HSA-556833
Cholesterol biosynthesis R-HSA-191273

Expression Atlas ENSG00000113161
NCBI gene (formerly Entrezgene) 3156
GeneCards 5006
HGNC Symbol HGNC:5006
MIM gene 142910
MIM morbid 142910
UniProtKB Gene Name P04035
WikiGene 3156
Gene: MAOB
Ensembl ID : ENSG00000069535
Description: monoamine oxidase B
Gene Synonyms:
14 APIs:
333 Possible Orthologues:

Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB R-HSA-141333
Amine Oxidase reactions R-HSA-140179
Biological oxidations R-HSA-211859
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB R-HSA-141333
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Amine Oxidase reactions R-HSA-140179
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB R-HSA-141333
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Amine Oxidase reactions R-HSA-140179
Phase I - Functionalization of compounds R-HSA-211945
Amine Oxidase reactions R-HSA-140179
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB R-HSA-141333
Amine Oxidase reactions R-HSA-140179
Metabolism R-HSA-1430728
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB R-HSA-141333
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Phase I - Functionalization of compounds R-HSA-211945
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB R-HSA-141333
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Amine Oxidase reactions R-HSA-140179
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB R-HSA-141333
Amine Oxidase reactions R-HSA-140179
Metabolism R-HSA-1430728

Expression Atlas ENSG00000069535
NCBI gene (formerly Entrezgene) 4129
GeneCards 6834
HGNC Symbol HGNC:6834
MIM gene 309860
UniProtKB Gene Name P27338
WikiGene 4129
Gene: CYP3A4
Ensembl ID : ENSG00000160868
Description: cytochrome P450 family 3 subfamily A member 4
Gene Synonyms: CYP3A3
3 APIs:
638 Possible Orthologues:

Xenobiotics R-HSA-211981
Biosynthesis of maresins R-HSA-9018682
Drug ADME R-HSA-9748784
Biological oxidations R-HSA-211859
Prednisone ADME R-HSA-9757110
Biosynthesis of maresin-like SPMs R-HSA-9027307
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Atorvastatin ADME R-HSA-9754706
Aflatoxin activation and detoxification R-HSA-5423646
Metabolism R-HSA-1430728
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Phase I - Functionalization of compounds R-HSA-211945
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of lipids R-HSA-556833
Aspirin ADME R-HSA-9749641
Biosynthesis of maresin-like SPMs R-HSA-9027307
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Drug ADME R-HSA-9748784
Atorvastatin ADME R-HSA-9754706
Biological oxidations R-HSA-211859
Aflatoxin activation and detoxification R-HSA-5423646
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Aspirin ADME R-HSA-9749641
Biosynthesis of maresins R-HSA-9018682
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Metabolism R-HSA-1430728
Xenobiotics R-HSA-211981
Prednisone ADME R-HSA-9757110
Cytochrome P450 - arranged by substrate type R-HSA-211897
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Biosynthesis of maresin-like SPMs R-HSA-9027307
Biosynthesis of maresins R-HSA-9018682
Metabolism R-HSA-1430728
Xenobiotics R-HSA-211981
Drug ADME R-HSA-9748784
Aflatoxin activation and detoxification R-HSA-5423646
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Phase I - Functionalization of compounds R-HSA-211945
Aspirin ADME R-HSA-9749641
Prednisone ADME R-HSA-9757110
Metabolism of lipids R-HSA-556833
Biological oxidations R-HSA-211859
Atorvastatin ADME R-HSA-9754706
Cytochrome P450 - arranged by substrate type R-HSA-211897
Phase I - Functionalization of compounds R-HSA-211945
Aflatoxin activation and detoxification R-HSA-5423646
Metabolism of lipids R-HSA-556833
Prednisone ADME R-HSA-9757110
Metabolism R-HSA-1430728
Atorvastatin ADME R-HSA-9754706
Drug ADME R-HSA-9748784
Biological oxidations R-HSA-211859
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Biosynthesis of maresin-like SPMs R-HSA-9027307
Biosynthesis of maresins R-HSA-9018682
Cytochrome P450 - arranged by substrate type R-HSA-211897
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Aspirin ADME R-HSA-9749641
Xenobiotics R-HSA-211981
Phase I - Functionalization of compounds R-HSA-211945
Aflatoxin activation and detoxification R-HSA-5423646
Drug ADME R-HSA-9748784
Aspirin ADME R-HSA-9749641
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Cytochrome P450 - arranged by substrate type R-HSA-211897
Atorvastatin ADME R-HSA-9754706
Biosynthesis of maresins R-HSA-9018682
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Biosynthesis of maresin-like SPMs R-HSA-9027307
Metabolism of lipids R-HSA-556833
Xenobiotics R-HSA-211981
Prednisone ADME R-HSA-9757110
Metabolism of lipids R-HSA-556833
Biological oxidations R-HSA-211859
Aflatoxin activation and detoxification R-HSA-5423646
Cytochrome P450 - arranged by substrate type R-HSA-211897
Drug ADME R-HSA-9748784
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of maresins R-HSA-9018682
Xenobiotics R-HSA-211981
Aspirin ADME R-HSA-9749641
Phase I - Functionalization of compounds R-HSA-211945
Biosynthesis of maresin-like SPMs R-HSA-9027307
Prednisone ADME R-HSA-9757110
Metabolism R-HSA-1430728
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Atorvastatin ADME R-HSA-9754706
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Biosynthesis of maresins R-HSA-9018682
Biological oxidations R-HSA-211859
Atorvastatin ADME R-HSA-9754706
Xenobiotics R-HSA-211981
Cytochrome P450 - arranged by substrate type R-HSA-211897
Aspirin ADME R-HSA-9749641
Aflatoxin activation and detoxification R-HSA-5423646
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Metabolism of lipids R-HSA-556833
Drug ADME R-HSA-9748784
Biosynthesis of maresin-like SPMs R-HSA-9027307
Prednisone ADME R-HSA-9757110
Aspirin ADME R-HSA-9749641
Phase I - Functionalization of compounds R-HSA-211945
Biosynthesis of maresin-like SPMs R-HSA-9027307
Drug ADME R-HSA-9748784
Metabolism of lipids R-HSA-556833
Xenobiotics R-HSA-211981
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of maresins R-HSA-9018682
Biological oxidations R-HSA-211859
Aflatoxin activation and detoxification R-HSA-5423646
Metabolism R-HSA-1430728
Atorvastatin ADME R-HSA-9754706
Cytochrome P450 - arranged by substrate type R-HSA-211897
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Prednisone ADME R-HSA-9757110
Atorvastatin ADME R-HSA-9754706
Biosynthesis of maresins R-HSA-9018682
Aspirin ADME R-HSA-9749641
Biological oxidations R-HSA-211859
Xenobiotics R-HSA-211981
Aflatoxin activation and detoxification R-HSA-5423646
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Biosynthesis of maresin-like SPMs R-HSA-9027307
Cytochrome P450 - arranged by substrate type R-HSA-211897
Drug ADME R-HSA-9748784
Prednisone ADME R-HSA-9757110
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Phase I - Functionalization of compounds R-HSA-211945

Expression Atlas ENSG00000160868
NCBI gene (formerly Entrezgene) 1576
GeneCards 2637
HGNC Symbol HGNC:2637
MIM gene 124010
MIM morbid 619073
UniProtKB Gene Name Q6GRK0
WikiGene 1576
Gene: HPD
Ensembl ID : ENSG00000158104
Description: 4-hydroxyphenylpyruvate dioxygenase
Gene Synonyms: 4-HPPD,4HPPD,GLOD3,PPD
1 APIs:
207 Possible Orthologues:

Phenylalanine and tyrosine metabolism R-HSA-8963691
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism of amino acids and derivatives R-HSA-71291
Tyrosine catabolism R-HSA-8963684
Metabolism R-HSA-1430728
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Phenylalanine and tyrosine metabolism R-HSA-8963691
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
Phenylalanine and tyrosine metabolism R-HSA-8963691
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Tyrosine catabolism R-HSA-8963684
Metabolism R-HSA-1430728
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism R-HSA-1430728
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism of amino acids and derivatives R-HSA-71291
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
Phenylalanine and tyrosine metabolism R-HSA-8963691
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism R-HSA-1430728
Tyrosine catabolism R-HSA-8963684
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Phenylalanine and tyrosine metabolism R-HSA-8963691
Tyrosine catabolism R-HSA-8963684
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism R-HSA-1430728

Expression Atlas ENSG00000158104
NCBI gene (formerly Entrezgene) 3242
GeneCards 5147
HGNC Symbol HGNC:5147
MIM gene 609695
MIM morbid 276710
UniProtKB Gene Name A0A0B4J1R4
WikiGene 3242