Gene: MAPK1
Ensembl ID : ENSG00000100030
Description: mitogen-activated protein kinase 1
Gene Synonyms: ERK,ERK2,MAPK2,P41MAPK,PRKM1,PRKM2
6 APIs:
214 Possible Orthologues:

Signaling by MAP2K mutants R-HSA-9652169
Hemostasis R-HSA-109582
MAP kinase activation R-HSA-450294
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cytokine Signaling in Immune system R-HSA-1280215
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Infection with Mycobacterium tuberculosis R-HSA-9635486
Ca-dependent events R-HSA-111996
Signaling by MAPK mutants R-HSA-9652817
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Negative regulation of FGFR2 signaling R-HSA-5654727
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Signaling by Rho GTPases R-HSA-194315
Signaling by TGFB family members R-HSA-9006936
Signaling by FGFR4 R-HSA-5654743
Transcriptional Regulation by NPAS4 R-HSA-9634815
Toll-like Receptor Cascades R-HSA-168898
Signaling by GPCR R-HSA-372790
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Opioid Signalling R-HSA-111885
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Leishmania phagocytosis R-HSA-9664417
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
PLC beta mediated events R-HSA-112043
Signaling by NTRK1 (TRKA) R-HSA-187037
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
MAPK1/MAPK3 signaling R-HSA-5684996
Platelet activation, signaling and aggregation R-HSA-76002
Oxidative Stress Induced Senescence R-HSA-2559580
Negative regulation of MAPK pathway R-HSA-5675221
ERK/MAPK targets R-HSA-198753
Intracellular signaling by second messengers R-HSA-9006925
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by Insulin receptor R-HSA-74752
Post NMDA receptor activation events R-HSA-438064
Recycling pathway of L1 R-HSA-437239
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by RAF1 mutants R-HSA-9656223
Suppression of apoptosis R-HSA-9635465
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
RUNX2 regulates bone development R-HSA-8941326
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling by MAP2K mutants R-HSA-9652169
MyD88-independent TLR4 cascade R-HSA-166166
phospho-PLA2 pathway R-HSA-111995
Parasite infection R-HSA-9664407
PIP3 activates AKT signaling R-HSA-1257604
MAPK family signaling cascades R-HSA-5683057
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Infectious disease R-HSA-5663205
Mitotic Prophase R-HSA-68875
Negative regulation of FGFR3 signaling R-HSA-5654732
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Growth hormone receptor signaling R-HSA-982772
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
ERKs are inactivated R-HSA-202670
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Neuronal System R-HSA-112316
MAPK1 (ERK2) activation R-HSA-112411
Negative regulation of FGFR1 signaling R-HSA-5654726
Neutrophil degranulation R-HSA-6798695
Oncogenic MAPK signaling R-HSA-6802957
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by NODAL R-HSA-1181150
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal transduction by L1 R-HSA-445144
Signaling by ALK in cancer R-HSA-9700206
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
RAF-independent MAPK1/3 activation R-HSA-112409
Gene expression (Transcription) R-HSA-74160
Regulation of the apoptosome activity R-HSA-9627069
Signaling by Interleukins R-HSA-449147
Signaling by FGFR2 R-HSA-5654738
Frs2-mediated activation R-HSA-170968
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MyD88 dependent cascade initiated on endosome R-HSA-975155
Prolonged ERK activation events R-HSA-169893
L1CAM interactions R-HSA-373760
Innate Immune System R-HSA-168249
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
G alpha (i) signalling events R-HSA-418594
PTEN Regulation R-HSA-6807070
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signalling to ERKs R-HSA-187687
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Formation of apoptosome R-HSA-111458
ESR-mediated signaling R-HSA-8939211
Insulin receptor signalling cascade R-HSA-74751
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Axon guidance R-HSA-422475
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Regulation of PTEN gene transcription R-HSA-8943724
Oncogene Induced Senescence R-HSA-2559585
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Activin R-HSA-1502540
FCERI mediated MAPK activation R-HSA-2871796
RAF/MAP kinase cascade R-HSA-5673001
Intrinsic Pathway for Apoptosis R-HSA-109606
Transmission across Chemical Synapses R-HSA-112315
Generic Transcription Pathway R-HSA-212436
NCAM signaling for neurite out-growth R-HSA-375165
Signaling downstream of RAS mutants R-HSA-9649948
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by FGFR3 R-HSA-5654741
Signaling by RAS mutants R-HSA-6802949
Apoptosis R-HSA-109581
Immune System R-HSA-168256
Negative feedback regulation of MAPK pathway R-HSA-5674499
Spry regulation of FGF signaling R-HSA-1295596
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by NTRKs R-HSA-166520
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
RHO GTPase Effectors R-HSA-195258
Cellular response to heat stress R-HSA-3371556
Signal attenuation R-HSA-74749
Transcriptional regulation by RUNX2 R-HSA-8878166
Leishmania infection R-HSA-9658195
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by FGFR1 R-HSA-5654736
Programmed Cell Death R-HSA-5357801
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
M Phase R-HSA-68886
G alpha (q) signalling events R-HSA-416476
RSK activation R-HSA-444257
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Negative regulation of the PI3K/AKT network R-HSA-199418
Negative regulation of FGFR4 signaling R-HSA-5654733
Signal Transduction R-HSA-162582
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cellular Senescence R-HSA-2559583
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cell Cycle, Mitotic R-HSA-69278
FCGR3A-mediated phagocytosis R-HSA-9664422
MAP kinase activation R-HSA-450294
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Response of Mtb to phagocytosis R-HSA-9637690
GPCR downstream signalling R-HSA-388396
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Nuclear Receptors R-HSA-9006931
NPAS4 regulates expression of target genes R-HSA-9768919
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by FGFR R-HSA-190236
MAP2K and MAPK activation R-HSA-5674135
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Apoptotic factor-mediated response R-HSA-111471
Oxidative Stress Induced Senescence R-HSA-2559580
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by NTRK1 (TRKA) R-HSA-187037
phospho-PLA2 pathway R-HSA-111995
Signal Transduction R-HSA-162582
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
MyD88 cascade initiated on plasma membrane R-HSA-975871
Transmission across Chemical Synapses R-HSA-112315
Intracellular signaling by second messengers R-HSA-9006925
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
NCAM signaling for neurite out-growth R-HSA-375165
Negative regulation of the PI3K/AKT network R-HSA-199418
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by ALK in cancer R-HSA-9700206
Oncogenic MAPK signaling R-HSA-6802957
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
G-protein mediated events R-HSA-112040
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Post NMDA receptor activation events R-HSA-438064
Extra-nuclear estrogen signaling R-HSA-9009391
Cellular responses to stimuli R-HSA-8953897
Apoptotic factor-mediated response R-HSA-111471
Ca-dependent events R-HSA-111996
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Mitotic Prophase R-HSA-68875
Axon guidance R-HSA-422475
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAPK1/MAPK3 signaling R-HSA-5684996
Neutrophil degranulation R-HSA-6798695
Insulin receptor signalling cascade R-HSA-74751
Negative feedback regulation of MAPK pathway R-HSA-5674499
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Signaling by Insulin receptor R-HSA-74752
MyD88-independent TLR4 cascade R-HSA-166166
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Transcriptional regulation by RUNX2 R-HSA-8878166
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Hemostasis R-HSA-109582
Response of Mtb to phagocytosis R-HSA-9637690
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
Opioid Signalling R-HSA-111885
Infection with Mycobacterium tuberculosis R-HSA-9635486
Leishmania infection R-HSA-9658195
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cellular response to heat stress R-HSA-3371556
Signaling by NTRKs R-HSA-166520
Signaling by Activin R-HSA-1502540
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
FCGR3A-mediated phagocytosis R-HSA-9664422
Apoptosis R-HSA-109581
Negative regulation of MAPK pathway R-HSA-5675221
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by TGFB family members R-HSA-9006936
RUNX2 regulates bone development R-HSA-8941326
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
G alpha (i) signalling events R-HSA-418594
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR4 R-HSA-5654743
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signal transduction by L1 R-HSA-445144
GPCR downstream signalling R-HSA-388396
Negative regulation of FGFR4 signaling R-HSA-5654733
Negative regulation of FGFR2 signaling R-HSA-5654727
Infectious disease R-HSA-5663205
MyD88 dependent cascade initiated on endosome R-HSA-975155
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Developmental Biology R-HSA-1266738
Regulation of PTEN gene transcription R-HSA-8943724
ERKs are inactivated R-HSA-202670
Signaling by NODAL R-HSA-1181150
RSK activation R-HSA-444257
Activation of the AP-1 family of transcription factors R-HSA-450341
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
Signaling by MAP2K mutants R-HSA-9652169
Prolonged ERK activation events R-HSA-169893
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Regulation of the apoptosome activity R-HSA-9627069
PLC beta mediated events R-HSA-112043
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Leishmania phagocytosis R-HSA-9664417
ERK/MAPK targets R-HSA-198753
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
Signal attenuation R-HSA-74749
Growth hormone receptor signaling R-HSA-982772
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Interleukin-17 signaling R-HSA-448424
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by MAPK mutants R-HSA-9652817
Oncogene Induced Senescence R-HSA-2559585
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Recycling pathway of L1 R-HSA-437239
ESR-mediated signaling R-HSA-8939211
Disease R-HSA-1643685
Parasite infection R-HSA-9664407
Negative regulation of FGFR3 signaling R-HSA-5654732
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by FGFR2 R-HSA-5654738
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PTEN Regulation R-HSA-6807070
Signaling by Rho GTPases R-HSA-194315
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
M Phase R-HSA-68886
Innate Immune System R-HSA-168249
RHO GTPase Effectors R-HSA-195258
MAP kinase activation R-HSA-450294
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Frs2-mediated activation R-HSA-170968
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by FGFR1 R-HSA-5654736
Cellular responses to stress R-HSA-2262752
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Cell Cycle, Mitotic R-HSA-69278
FCERI mediated MAPK activation R-HSA-2871796
MAP2K and MAPK activation R-HSA-5674135
Suppression of apoptosis R-HSA-9635465
RAF/MAP kinase cascade R-HSA-5673001
Formation of apoptosome R-HSA-111458
MAPK1 (ERK2) activation R-HSA-112411
Neuronal System R-HSA-112316
Cellular Senescence R-HSA-2559583
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Intrinsic Pathway for Apoptosis R-HSA-109606
Signalling to ERKs R-HSA-187687
Programmed Cell Death R-HSA-5357801
Signaling by RAS mutants R-HSA-6802949
Cell Cycle R-HSA-1640170
Signaling by Interleukins R-HSA-449147
Gene expression (Transcription) R-HSA-74160
NPAS4 regulates expression of target genes R-HSA-9768919
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by FGFR R-HSA-190236
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
L1CAM interactions R-HSA-373760
PIP3 activates AKT signaling R-HSA-1257604
Toll-like Receptor Cascades R-HSA-168898
Signaling by FGFR3 R-HSA-5654741
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Oncogenic MAPK signaling R-HSA-6802957
Suppression of apoptosis R-HSA-9635465
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
ESR-mediated signaling R-HSA-8939211
Regulation of the apoptosome activity R-HSA-9627069
Cytokine Signaling in Immune system R-HSA-1280215
ERKs are inactivated R-HSA-202670
PLC beta mediated events R-HSA-112043
Oncogene Induced Senescence R-HSA-2559585
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
GPCR downstream signalling R-HSA-388396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by RAF1 mutants R-HSA-9656223
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX2 R-HSA-8878166
PIP3 activates AKT signaling R-HSA-1257604
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Opioid Signalling R-HSA-111885
Transmission across Chemical Synapses R-HSA-112315
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by FGFR2 R-HSA-5654738
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Insulin receptor signalling cascade R-HSA-74751
Prolonged ERK activation events R-HSA-169893
Parasite infection R-HSA-9664407
G alpha (i) signalling events R-HSA-418594
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
RUNX2 regulates bone development R-HSA-8941326
Signaling by GPCR R-HSA-372790
Toll-like Receptor Cascades R-HSA-168898
Transcriptional Regulation by NPAS4 R-HSA-9634815
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
L1CAM interactions R-HSA-373760
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Programmed Cell Death R-HSA-5357801
Frs2-mediated activation R-HSA-170968
Signaling downstream of RAS mutants R-HSA-9649948
FCERI mediated MAPK activation R-HSA-2871796
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by FGFR R-HSA-190236
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Recycling pathway of L1 R-HSA-437239
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Gene expression (Transcription) R-HSA-74160
Signal transduction by L1 R-HSA-445144
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Leishmania infection R-HSA-9658195
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
PTEN Regulation R-HSA-6807070
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Apoptotic factor-mediated response R-HSA-111471
Signal attenuation R-HSA-74749
Response of Mtb to phagocytosis R-HSA-9637690
Signaling by ALK in cancer R-HSA-9700206
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Immune System R-HSA-168256
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cytochrome c-mediated apoptotic response R-HSA-111461
RAF-independent MAPK1/3 activation R-HSA-112409
Ca-dependent events R-HSA-111996
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Post NMDA receptor activation events R-HSA-438064
Hemostasis R-HSA-109582
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Innate Immune System R-HSA-168249
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Rho GTPases R-HSA-194315
Signaling by Interleukins R-HSA-449147
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR3 R-HSA-5654741
MAP2K and MAPK activation R-HSA-5674135
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Intracellular signaling by second messengers R-HSA-9006925
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Activation of the AP-1 family of transcription factors R-HSA-450341
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by RAS mutants R-HSA-6802949
Regulation of PTEN gene transcription R-HSA-8943724
Platelet activation, signaling and aggregation R-HSA-76002
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
M Phase R-HSA-68886
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Formation of apoptosome R-HSA-111458
Negative regulation of FGFR2 signaling R-HSA-5654727
Disease R-HSA-1643685
MAP kinase activation R-HSA-450294
Mitotic Prophase R-HSA-68875
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Apoptosis R-HSA-109581
Signaling by Activin R-HSA-1502540
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
G alpha (q) signalling events R-HSA-416476
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
G-protein mediated events R-HSA-112040
FCGR3A-mediated phagocytosis R-HSA-9664422
MyD88 cascade initiated on plasma membrane R-HSA-975871
Developmental Biology R-HSA-1266738
Growth hormone receptor signaling R-HSA-982772
Neuronal System R-HSA-112316
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by NTRKs R-HSA-166520
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Axon guidance R-HSA-422475
Infection with Mycobacterium tuberculosis R-HSA-9635486
Extra-nuclear estrogen signaling R-HSA-9009391
Signalling to ERKs R-HSA-187687
RHO GTPase Effectors R-HSA-195258
Cell Cycle, Mitotic R-HSA-69278
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Neutrophil degranulation R-HSA-6798695
RNA Polymerase II Transcription R-HSA-73857
Signaling by Insulin receptor R-HSA-74752
Negative regulation of FGFR4 signaling R-HSA-5654733
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Negative feedback regulation of MAPK pathway R-HSA-5674499
Negative regulation of the PI3K/AKT network R-HSA-199418
Generic Transcription Pathway R-HSA-212436
phospho-PLA2 pathway R-HSA-111995
Signaling by Nuclear Receptors R-HSA-9006931
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Spry regulation of FGF signaling R-HSA-1295596
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling by NODAL R-HSA-1181150
Cellular responses to stimuli R-HSA-8953897
MAPK1 (ERK2) activation R-HSA-112411
Signaling by TGFB family members R-HSA-9006936
RSK activation R-HSA-444257
Cellular response to heat stress R-HSA-3371556
Cellular responses to stress R-HSA-2262752
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by TGF-beta Receptor Complex R-HSA-170834
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
ERK/MAPK targets R-HSA-198753
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR4 R-HSA-5654743
Signaling by MAPK mutants R-HSA-9652817
Signaling by FGFR1 R-HSA-5654736
Leishmania phagocytosis R-HSA-9664417
NCAM signaling for neurite out-growth R-HSA-375165
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Negative regulation of FGFR3 signaling R-HSA-5654732
Nervous system development R-HSA-9675108
Interleukin-17 signaling R-HSA-448424
Signal Transduction R-HSA-162582
Cellular Senescence R-HSA-2559583
Negative regulation of MAPK pathway R-HSA-5675221
Advanced glycosylation endproduct receptor signaling R-HSA-879415
RSK activation R-HSA-444257
G alpha (i) signalling events R-HSA-418594
Cellular responses to stimuli R-HSA-8953897
RUNX2 regulates bone development R-HSA-8941326
Developmental Biology R-HSA-1266738
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Regulation of PTEN gene transcription R-HSA-8943724
ERK/MAPK targets R-HSA-198753
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Oncogenic MAPK signaling R-HSA-6802957
Platelet activation, signaling and aggregation R-HSA-76002
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Apoptosis R-HSA-109581
Negative regulation of FGFR3 signaling R-HSA-5654732
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NODAL R-HSA-1181150
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Nuclear Receptors R-HSA-9006931
Prolonged ERK activation events R-HSA-169893
Signaling by FGFR4 R-HSA-5654743
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Growth hormone receptor signaling R-HSA-982772
Signaling by ALK in cancer R-HSA-9700206
Negative regulation of MAPK pathway R-HSA-5675221
phospho-PLA2 pathway R-HSA-111995
Oncogene Induced Senescence R-HSA-2559585
Negative feedback regulation of MAPK pathway R-HSA-5674499
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Cell Cycle R-HSA-1640170
MAP2K and MAPK activation R-HSA-5674135
Neuronal System R-HSA-112316
MyD88 dependent cascade initiated on endosome R-HSA-975155
Recycling pathway of L1 R-HSA-437239
Signaling by FGFR3 R-HSA-5654741
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Axon guidance R-HSA-422475
Insulin receptor signalling cascade R-HSA-74751
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Rho GTPases R-HSA-194315
Cell Cycle, Mitotic R-HSA-69278
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Cytochrome c-mediated apoptotic response R-HSA-111461
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by RAS mutants R-HSA-6802949
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Negative regulation of FGFR4 signaling R-HSA-5654733
ERKs are inactivated R-HSA-202670
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Infectious disease R-HSA-5663205
Signaling by FGFR R-HSA-190236
Cellular Senescence R-HSA-2559583
FCGR3A-mediated phagocytosis R-HSA-9664422
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
ESR-mediated signaling R-HSA-8939211
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
MAP kinase activation R-HSA-450294
Transcriptional regulation by RUNX2 R-HSA-8878166
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling downstream of RAS mutants R-HSA-9649948
Programmed Cell Death R-HSA-5357801
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Gene expression (Transcription) R-HSA-74160
Spry regulation of FGF signaling R-HSA-1295596
Signaling by Interleukins R-HSA-449147
MyD88 cascade initiated on plasma membrane R-HSA-975871
Post NMDA receptor activation events R-HSA-438064
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
GPCR downstream signalling R-HSA-388396
Parasite infection R-HSA-9664407
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
L1CAM interactions R-HSA-373760
Signaling by FGFR2 R-HSA-5654738
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by NTRK1 (TRKA) R-HSA-187037
Transmission across Chemical Synapses R-HSA-112315
Neutrophil degranulation R-HSA-6798695
Cytokine Signaling in Immune system R-HSA-1280215
RAF/MAP kinase cascade R-HSA-5673001
Opioid Signalling R-HSA-111885
Mitotic Prophase R-HSA-68875
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Toll-like Receptor Cascades R-HSA-168898
Signal Transduction R-HSA-162582
RHO GTPase Effectors R-HSA-195258
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by RAF1 mutants R-HSA-9656223
Apoptotic factor-mediated response R-HSA-111471
Signaling by TGFB family members R-HSA-9006936
Regulation of the apoptosome activity R-HSA-9627069
Leishmania phagocytosis R-HSA-9664417
Signaling by MAP2K mutants R-HSA-9652169
MAPK family signaling cascades R-HSA-5683057
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
RNA Polymerase II Transcription R-HSA-73857
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by FGFR1 R-HSA-5654736
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Frs2-mediated activation R-HSA-170968
NPAS4 regulates expression of target genes R-HSA-9768919
Infection with Mycobacterium tuberculosis R-HSA-9635486
Formation of apoptosome R-HSA-111458
Ca-dependent events R-HSA-111996
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Immune System R-HSA-168256
M Phase R-HSA-68886
PLC beta mediated events R-HSA-112043
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
MyD88-independent TLR4 cascade R-HSA-166166
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Advanced glycosylation endproduct receptor signaling R-HSA-879415
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Transcriptional Regulation by NPAS4 R-HSA-9634815
PTEN Regulation R-HSA-6807070
G alpha (q) signalling events R-HSA-416476
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cellular response to heat stress R-HSA-3371556
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Suppression of apoptosis R-HSA-9635465
Signaling by MAPK mutants R-HSA-9652817
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by GPCR R-HSA-372790
Signaling by Insulin receptor R-HSA-74752
Leishmania infection R-HSA-9658195
Signal transduction by L1 R-HSA-445144
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Oxidative Stress Induced Senescence R-HSA-2559580
Negative regulation of FGFR2 signaling R-HSA-5654727
G-protein mediated events R-HSA-112040
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by NTRKs R-HSA-166520
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Activin R-HSA-1502540
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signal attenuation R-HSA-74749
Signalling to ERKs R-HSA-187687
Signaling by TGF-beta Receptor Complex R-HSA-170834
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
MAPK1 (ERK2) activation R-HSA-112411
Negative regulation of FGFR1 signaling R-HSA-5654726
FCERI mediated MAPK activation R-HSA-2871796
MAPK1/MAPK3 signaling R-HSA-5684996
Response of Mtb to phagocytosis R-HSA-9637690
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
PIP3 activates AKT signaling R-HSA-1257604
Cytochrome c-mediated apoptotic response R-HSA-111461
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by GPCR R-HSA-372790
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
RUNX2 regulates bone development R-HSA-8941326
Signaling by MAP2K mutants R-HSA-9652169
RAF/MAP kinase cascade R-HSA-5673001
Cell Cycle, Mitotic R-HSA-69278
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by TGF-beta Receptor Complex R-HSA-170834
Apoptosis R-HSA-109581
Gene expression (Transcription) R-HSA-74160
Transmission across Chemical Synapses R-HSA-112315
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Ca-dependent events R-HSA-111996
Suppression of apoptosis R-HSA-9635465
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Oxidative Stress Induced Senescence R-HSA-2559580
Neuronal System R-HSA-112316
Cellular response to heat stress R-HSA-3371556
Platelet activation, signaling and aggregation R-HSA-76002
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Negative regulation of MAPK pathway R-HSA-5675221
Formation of apoptosome R-HSA-111458
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by NTRKs R-HSA-166520
Signaling by RAS mutants R-HSA-6802949
MAP kinase activation R-HSA-450294
Signaling by ALK fusions and activated point mutants R-HSA-9725370
MAPK1/MAPK3 signaling R-HSA-5684996
RSK activation R-HSA-444257
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Programmed Cell Death R-HSA-5357801
Signal attenuation R-HSA-74749
Infection with Mycobacterium tuberculosis R-HSA-9635486
Neutrophil degranulation R-HSA-6798695
Signaling by FGFR3 R-HSA-5654741
Prolonged ERK activation events R-HSA-169893
Growth hormone receptor signaling R-HSA-982772
G-protein mediated events R-HSA-112040
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Generic Transcription Pathway R-HSA-212436
Spry regulation of FGF signaling R-HSA-1295596
Negative regulation of FGFR3 signaling R-HSA-5654732
MAPK1 (ERK2) activation R-HSA-112411
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NODAL R-HSA-1181150
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of the apoptosome activity R-HSA-9627069
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR4 R-HSA-5654743
MAPK family signaling cascades R-HSA-5683057
Signaling by RAF1 mutants R-HSA-9656223
Signaling downstream of RAS mutants R-HSA-9649948
Leishmania phagocytosis R-HSA-9664417
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
M Phase R-HSA-68886
Oncogenic MAPK signaling R-HSA-6802957
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Rho GTPases R-HSA-194315
Extra-nuclear estrogen signaling R-HSA-9009391
MyD88-independent TLR4 cascade R-HSA-166166
Oncogene Induced Senescence R-HSA-2559585
Cellular responses to stress R-HSA-2262752
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Signal transduction by L1 R-HSA-445144
Leishmania infection R-HSA-9658195
Frs2-mediated activation R-HSA-170968
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
PLC beta mediated events R-HSA-112043
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
ERK/MAPK targets R-HSA-198753
Signaling by Activin R-HSA-1502540
MAP2K and MAPK activation R-HSA-5674135
Nervous system development R-HSA-9675108
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Signaling by Nuclear Receptors R-HSA-9006931
Negative regulation of the PI3K/AKT network R-HSA-199418
RAF-independent MAPK1/3 activation R-HSA-112409
FCERI mediated MAPK activation R-HSA-2871796
Innate Immune System R-HSA-168249
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-17 signaling R-HSA-448424
Disease R-HSA-1643685
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by FGFR2 R-HSA-5654738
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Infectious disease R-HSA-5663205
phospho-PLA2 pathway R-HSA-111995
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional Regulation by NPAS4 R-HSA-9634815
Mitotic Prophase R-HSA-68875
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Recycling pathway of L1 R-HSA-437239
Cellular Senescence R-HSA-2559583
Signaling by NTRK1 (TRKA) R-HSA-187037
Intrinsic Pathway for Apoptosis R-HSA-109606
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
RHO GTPase Effectors R-HSA-195258
PTEN Regulation R-HSA-6807070
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signalling to ERKs R-HSA-187687
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MyD88 cascade initiated on plasma membrane R-HSA-975871
G alpha (q) signalling events R-HSA-416476
Signaling by FGFR R-HSA-190236
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by Insulin receptor R-HSA-74752
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Hemostasis R-HSA-109582
Signaling by MAPK mutants R-HSA-9652817
ESR-mediated signaling R-HSA-8939211
Post NMDA receptor activation events R-HSA-438064
Cell Cycle R-HSA-1640170
Parasite infection R-HSA-9664407
Signaling by FGFR1 R-HSA-5654736
Opioid Signalling R-HSA-111885
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCGR3A-mediated phagocytosis R-HSA-9664422
Negative regulation of FGFR2 signaling R-HSA-5654727
Apoptotic factor-mediated response R-HSA-111471
Signaling by ALK in cancer R-HSA-9700206
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by TGFB family members R-HSA-9006936
Immune System R-HSA-168256
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
L1CAM interactions R-HSA-373760
GPCR downstream signalling R-HSA-388396
Transcriptional regulation by RUNX2 R-HSA-8878166
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Cellular responses to stimuli R-HSA-8953897
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by Interleukins R-HSA-449147
Response of Mtb to phagocytosis R-HSA-9637690
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
ERKs are inactivated R-HSA-202670
RUNX2 regulates osteoblast differentiation R-HSA-8940973
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Intracellular signaling by second messengers R-HSA-9006925
MyD88 cascade initiated on plasma membrane R-HSA-975871
Leishmania infection R-HSA-9658195
Prolonged ERK activation events R-HSA-169893
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
phospho-PLA2 pathway R-HSA-111995
Programmed Cell Death R-HSA-5357801
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Interleukins R-HSA-449147
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signalling to ERKs R-HSA-187687
Signaling by MAP2K mutants R-HSA-9652169
Signaling by GPCR R-HSA-372790
Signal attenuation R-HSA-74749
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
Cell Cycle, Mitotic R-HSA-69278
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
ERKs are inactivated R-HSA-202670
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cytochrome c-mediated apoptotic response R-HSA-111461
GPCR downstream signalling R-HSA-388396
FCERI mediated MAPK activation R-HSA-2871796
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by FGFR1 R-HSA-5654736
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Negative regulation of MAPK pathway R-HSA-5675221
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MAPK1/MAPK3 signaling R-HSA-5684996
Suppression of apoptosis R-HSA-9635465
Cellular response to heat stress R-HSA-3371556
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Negative regulation of FGFR1 signaling R-HSA-5654726
MAP2K and MAPK activation R-HSA-5674135
Immune System R-HSA-168256
Interleukin-17 signaling R-HSA-448424
Signaling by RAF1 mutants R-HSA-9656223
MAPK1 (ERK2) activation R-HSA-112411
Signaling by BRAF and RAF1 fusions R-HSA-6802952
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by TGF-beta Receptor Complex R-HSA-170834
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Infection with Mycobacterium tuberculosis R-HSA-9635486
Toll-like Receptor Cascades R-HSA-168898
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Axon guidance R-HSA-422475
Neutrophil degranulation R-HSA-6798695
Leishmania phagocytosis R-HSA-9664417
PTEN Regulation R-HSA-6807070
Regulation of PTEN gene transcription R-HSA-8943724
Post NMDA receptor activation events R-HSA-438064
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by TGFB family members R-HSA-9006936
Signaling by MAPK mutants R-HSA-9652817
Apoptotic factor-mediated response R-HSA-111471
Frs2-mediated activation R-HSA-170968
Signaling by Rho GTPases R-HSA-194315
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Transmission across Chemical Synapses R-HSA-112315
Gene expression (Transcription) R-HSA-74160
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Negative regulation of the PI3K/AKT network R-HSA-199418
Generic Transcription Pathway R-HSA-212436
Neuronal System R-HSA-112316
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signal transduction by L1 R-HSA-445144
RSK activation R-HSA-444257
NCAM signaling for neurite out-growth R-HSA-375165
Ca-dependent events R-HSA-111996
Signaling by FGFR R-HSA-190236
Disease R-HSA-1643685
ESR-mediated signaling R-HSA-8939211
Formation of apoptosome R-HSA-111458
NPAS4 regulates expression of target genes R-HSA-9768919
Oncogenic MAPK signaling R-HSA-6802957
Oncogene Induced Senescence R-HSA-2559585
ERK/MAPK targets R-HSA-198753
Signaling by FGFR4 R-HSA-5654743
Opioid Signalling R-HSA-111885
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by FGFR3 R-HSA-5654741
MyD88-independent TLR4 cascade R-HSA-166166
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Cellular responses to stress R-HSA-2262752
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling by RAS mutants R-HSA-6802949
Intrinsic Pathway for Apoptosis R-HSA-109606
G-protein mediated events R-HSA-112040
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
PLC beta mediated events R-HSA-112043
Signaling by NTRKs R-HSA-166520
Growth hormone receptor signaling R-HSA-982772
Parasite infection R-HSA-9664407
Signaling by NTRK1 (TRKA) R-HSA-187037
Developmental Biology R-HSA-1266738
FCGR3A-mediated phagocytosis R-HSA-9664422
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
RHO GTPase Effectors R-HSA-195258
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
M Phase R-HSA-68886
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by NODAL R-HSA-1181150
Signal Transduction R-HSA-162582
Oxidative Stress Induced Senescence R-HSA-2559580
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Nuclear Receptors R-HSA-9006931
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Cellular Senescence R-HSA-2559583
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by FGFR2 R-HSA-5654738
Recycling pathway of L1 R-HSA-437239
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of FGFR2 signaling R-HSA-5654727
Infectious disease R-HSA-5663205
Spry regulation of FGF signaling R-HSA-1295596
Mitotic Prophase R-HSA-68875
Innate Immune System R-HSA-168249
Hemostasis R-HSA-109582
Signaling by Activin R-HSA-1502540
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Regulation of HSF1-mediated heat shock response R-HSA-3371453
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
RAF-independent MAPK1/3 activation R-HSA-112409
MyD88 dependent cascade initiated on endosome R-HSA-975155
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cell Cycle R-HSA-1640170
Regulation of the apoptosome activity R-HSA-9627069
RNA Polymerase II Transcription R-HSA-73857
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
L1CAM interactions R-HSA-373760
Activation of the AP-1 family of transcription factors R-HSA-450341
G alpha (i) signalling events R-HSA-418594
Insulin receptor signalling cascade R-HSA-74751
Response of Mtb to phagocytosis R-HSA-9637690
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Apoptosis R-HSA-109581
Signaling by Insulin receptor R-HSA-74752
Signaling by ALK in cancer R-HSA-9700206
Transcriptional regulation by RUNX2 R-HSA-8878166
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RUNX2 regulates bone development R-HSA-8941326
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Opioid Signalling R-HSA-111885
Signaling by RAF1 mutants R-HSA-9656223
Transmission across Chemical Synapses R-HSA-112315
MAP2K and MAPK activation R-HSA-5674135
Axon guidance R-HSA-422475
Signaling by FGFR1 R-HSA-5654736
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
FCGR3A-mediated phagocytosis R-HSA-9664422
RAF/MAP kinase cascade R-HSA-5673001
Insulin receptor signalling cascade R-HSA-74751
Cellular responses to stress R-HSA-2262752
Signaling by FGFR2 R-HSA-5654738
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Negative regulation of FGFR4 signaling R-HSA-5654733
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Growth hormone receptor signaling R-HSA-982772
M Phase R-HSA-68886
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Spry regulation of FGF signaling R-HSA-1295596
Signaling by RAS mutants R-HSA-6802949
MAPK1/MAPK3 signaling R-HSA-5684996
MyD88-independent TLR4 cascade R-HSA-166166
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Frs2-mediated activation R-HSA-170968
Cellular Senescence R-HSA-2559583
Interleukin-17 signaling R-HSA-448424
Prolonged ERK activation events R-HSA-169893
Negative regulation of MAPK pathway R-HSA-5675221
Negative regulation of the PI3K/AKT network R-HSA-199418
Regulation of PTEN gene transcription R-HSA-8943724
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NODAL R-HSA-1181150
Negative regulation of FGFR1 signaling R-HSA-5654726
Immune System R-HSA-168256
Recycling pathway of L1 R-HSA-437239
Developmental Biology R-HSA-1266738
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
phospho-PLA2 pathway R-HSA-111995
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Neutrophil degranulation R-HSA-6798695
MAP kinase activation R-HSA-450294
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by Rho GTPases R-HSA-194315
Intracellular signaling by second messengers R-HSA-9006925
RUNX2 regulates bone development R-HSA-8941326
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by Nuclear Receptors R-HSA-9006931
Generic Transcription Pathway R-HSA-212436
Signal attenuation R-HSA-74749
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by NTRK1 (TRKA) R-HSA-187037
Parasite infection R-HSA-9664407
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by FGFR R-HSA-190236
Oxidative Stress Induced Senescence R-HSA-2559580
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
G-protein mediated events R-HSA-112040
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
RAF-independent MAPK1/3 activation R-HSA-112409
L1CAM interactions R-HSA-373760
Response of Mtb to phagocytosis R-HSA-9637690
Activation of NMDA receptors and postsynaptic events R-HSA-442755
GPCR downstream signalling R-HSA-388396
Regulation of HSF1-mediated heat shock response R-HSA-3371453
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by Interleukins R-HSA-449147
Signalling to ERKs R-HSA-187687
Signaling by MAPK mutants R-HSA-9652817
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Hemostasis R-HSA-109582
Signaling by GPCR R-HSA-372790
ERKs are inactivated R-HSA-202670
Mitotic Prophase R-HSA-68875
Suppression of apoptosis R-HSA-9635465
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 cascade initiated on plasma membrane R-HSA-975871
Disease R-HSA-1643685
Oncogenic MAPK signaling R-HSA-6802957
Regulation of the apoptosome activity R-HSA-9627069
Infectious disease R-HSA-5663205
Programmed Cell Death R-HSA-5357801
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Negative regulation of FGFR2 signaling R-HSA-5654727
Innate Immune System R-HSA-168249
Toll-like Receptor Cascades R-HSA-168898
Cytochrome c-mediated apoptotic response R-HSA-111461
Formation of apoptosome R-HSA-111458
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by ALK in cancer R-HSA-9700206
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Ca-dependent events R-HSA-111996
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Leishmania phagocytosis R-HSA-9664417
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
PIP3 activates AKT signaling R-HSA-1257604
ERK/MAPK targets R-HSA-198753
Signaling by TGFB family members R-HSA-9006936
PLC beta mediated events R-HSA-112043
Nervous system development R-HSA-9675108
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Signaling by NTRKs R-HSA-166520
Signaling by TGF-beta Receptor Complex R-HSA-170834
Apoptotic factor-mediated response R-HSA-111471
Oncogene Induced Senescence R-HSA-2559585
Signal transduction by L1 R-HSA-445144
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by FGFR3 R-HSA-5654741
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Gene expression (Transcription) R-HSA-74160
Cell Cycle, Mitotic R-HSA-69278
MyD88 dependent cascade initiated on endosome R-HSA-975155
Negative feedback regulation of MAPK pathway R-HSA-5674499
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RHO GTPase Effectors R-HSA-195258
FCERI mediated MAPK activation R-HSA-2871796
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Activin R-HSA-1502540
Signaling by MAP2K mutants R-HSA-9652169
Post NMDA receptor activation events R-HSA-438064
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cellular response to heat stress R-HSA-3371556
RSK activation R-HSA-444257
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Leishmania infection R-HSA-9658195
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by Insulin receptor R-HSA-74752
Activation of the AP-1 family of transcription factors R-HSA-450341
Platelet activation, signaling and aggregation R-HSA-76002
Cell Cycle R-HSA-1640170
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Apoptosis R-HSA-109581
G alpha (i) signalling events R-HSA-418594
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
ESR-mediated signaling R-HSA-8939211
Extra-nuclear estrogen signaling R-HSA-9009391
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
PTEN Regulation R-HSA-6807070
NPAS4 regulates expression of target genes R-HSA-9768919
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Signaling downstream of RAS mutants R-HSA-9649948
MAPK1 (ERK2) activation R-HSA-112411
Signaling by FGFR4 R-HSA-5654743
Neuronal System R-HSA-112316
Regulation of the apoptosome activity R-HSA-9627069
Signaling by FGFR4 R-HSA-5654743
Oncogenic MAPK signaling R-HSA-6802957
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signal transduction by L1 R-HSA-445144
Negative regulation of FGFR4 signaling R-HSA-5654733
G alpha (i) signalling events R-HSA-418594
Infectious disease R-HSA-5663205
Transmission across Chemical Synapses R-HSA-112315
Activation of the AP-1 family of transcription factors R-HSA-450341
PIP3 activates AKT signaling R-HSA-1257604
Signaling by RAS mutants R-HSA-6802949
Post NMDA receptor activation events R-HSA-438064
PTEN Regulation R-HSA-6807070
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
M Phase R-HSA-68886
Infection with Mycobacterium tuberculosis R-HSA-9635486
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Leishmania phagocytosis R-HSA-9664417
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by FGFR1 R-HSA-5654736
Signaling by BRAF and RAF1 fusions R-HSA-6802952
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Insulin receptor R-HSA-74752
MAPK1 (ERK2) activation R-HSA-112411
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by Activin R-HSA-1502540
MAP kinase activation R-HSA-450294
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Cell Cycle, Mitotic R-HSA-69278
Signaling by TGFB family members R-HSA-9006936
ERKs are inactivated R-HSA-202670
Recycling pathway of L1 R-HSA-437239
G-protein mediated events R-HSA-112040
Intracellular signaling by second messengers R-HSA-9006925
Extra-nuclear estrogen signaling R-HSA-9009391
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
RSK activation R-HSA-444257
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
L1CAM interactions R-HSA-373760
Transcriptional Regulation by NPAS4 R-HSA-9634815
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Regulation of PTEN gene transcription R-HSA-8943724
Ca-dependent events R-HSA-111996
Hemostasis R-HSA-109582
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of HSF1-mediated heat shock response R-HSA-3371453
GPCR downstream signalling R-HSA-388396
Axon guidance R-HSA-422475
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Innate Immune System R-HSA-168249
Cellular Senescence R-HSA-2559583
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by MAP2K mutants R-HSA-9652169
Signaling by NODAL R-HSA-1181150
Signaling by NTRKs R-HSA-166520
Apoptotic factor-mediated response R-HSA-111471
Cellular responses to stimuli R-HSA-8953897
Signaling by FGFR R-HSA-190236
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
Neuronal System R-HSA-112316
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Negative regulation of FGFR3 signaling R-HSA-5654732
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
Mitotic Prophase R-HSA-68875
Formation of apoptosome R-HSA-111458
Programmed Cell Death R-HSA-5357801
NCAM signaling for neurite out-growth R-HSA-375165
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Apoptosis R-HSA-109581
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by RAF1 mutants R-HSA-9656223
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Growth hormone receptor signaling R-HSA-982772
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
FCGR3A-mediated phagocytosis R-HSA-9664422
Platelet activation, signaling and aggregation R-HSA-76002
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by GPCR R-HSA-372790
ERK/MAPK targets R-HSA-198753
RUNX2 regulates bone development R-HSA-8941326
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by Interleukins R-HSA-449147
Negative regulation of FGFR1 signaling R-HSA-5654726
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Opioid Signalling R-HSA-111885
Signal attenuation R-HSA-74749
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Neutrophil degranulation R-HSA-6798695
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
RHO GTPase Effectors R-HSA-195258
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Immune System R-HSA-168256
FCERI mediated MAPK activation R-HSA-2871796
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
MyD88 dependent cascade initiated on endosome R-HSA-975155
Disease R-HSA-1643685
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by FGFR3 R-HSA-5654741
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
ESR-mediated signaling R-HSA-8939211
Parasite infection R-HSA-9664407
phospho-PLA2 pathway R-HSA-111995
Signalling to ERKs R-HSA-187687
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling downstream of RAS mutants R-HSA-9649948
NPAS4 regulates expression of target genes R-HSA-9768919
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Generic Transcription Pathway R-HSA-212436
Frs2-mediated activation R-HSA-170968
Leishmania infection R-HSA-9658195
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
MyD88-independent TLR4 cascade R-HSA-166166
RAF/MAP kinase cascade R-HSA-5673001
Oxidative Stress Induced Senescence R-HSA-2559580
Negative regulation of FGFR2 signaling R-HSA-5654727
Nervous system development R-HSA-9675108
MyD88 cascade initiated on plasma membrane R-HSA-975871
Oncogene Induced Senescence R-HSA-2559585
Prolonged ERK activation events R-HSA-169893
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Cellular response to heat stress R-HSA-3371556
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Negative regulation of MAPK pathway R-HSA-5675221
PLC beta mediated events R-HSA-112043
Signaling by ALK in cancer R-HSA-9700206
Toll-like Receptor Cascades R-HSA-168898
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR2 R-HSA-5654738
Negative feedback regulation of MAPK pathway R-HSA-5674499
MAP2K and MAPK activation R-HSA-5674135
Signaling by MAPK mutants R-HSA-9652817
Response of Mtb to phagocytosis R-HSA-9637690
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RNA Polymerase II Transcription R-HSA-73857
Interleukin-17 signaling R-HSA-448424
Cell Cycle R-HSA-1640170
Suppression of apoptosis R-HSA-9635465
RAF-independent MAPK1/3 activation R-HSA-112409
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G alpha (q) signalling events R-HSA-416476
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by TGF-beta Receptor Complex R-HSA-170834
Insulin receptor signalling cascade R-HSA-74751
MAP2K and MAPK activation R-HSA-5674135
Signaling by FGFR3 R-HSA-5654741
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
PLC beta mediated events R-HSA-112043
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Opioid Signalling R-HSA-111885
Infection with Mycobacterium tuberculosis R-HSA-9635486
RAF-independent MAPK1/3 activation R-HSA-112409
Cell Cycle, Mitotic R-HSA-69278
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by MAPK mutants R-HSA-9652817
G alpha (q) signalling events R-HSA-416476
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Immune System R-HSA-168256
Hemostasis R-HSA-109582
Neutrophil degranulation R-HSA-6798695
NPAS4 regulates expression of target genes R-HSA-9768919
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Post NMDA receptor activation events R-HSA-438064
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Oncogene Induced Senescence R-HSA-2559585
Signaling by Interleukins R-HSA-449147
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by GPCR R-HSA-372790
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Response of Mtb to phagocytosis R-HSA-9637690
ERKs are inactivated R-HSA-202670
Ca-dependent events R-HSA-111996
MyD88-independent TLR4 cascade R-HSA-166166
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signal Transduction R-HSA-162582
NCAM signaling for neurite out-growth R-HSA-375165
Activation of the AP-1 family of transcription factors R-HSA-450341
Regulation of the apoptosome activity R-HSA-9627069
Signaling by Insulin receptor R-HSA-74752
Formation of apoptosome R-HSA-111458
Cellular Senescence R-HSA-2559583
Advanced glycosylation endproduct receptor signaling R-HSA-879415
G-protein mediated events R-HSA-112040
ERK/MAPK targets R-HSA-198753
Innate Immune System R-HSA-168249
Cell Cycle R-HSA-1640170
Growth hormone receptor signaling R-HSA-982772
Signaling by FGFR1 R-HSA-5654736
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
RHO GTPase Effectors R-HSA-195258
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Rho GTPases R-HSA-194315
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by RAS mutants R-HSA-6802949
RNA Polymerase II Transcription R-HSA-73857
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
FCERI mediated MAPK activation R-HSA-2871796
RAF/MAP kinase cascade R-HSA-5673001
Signaling by MAP2K mutants R-HSA-9652169
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Oncogenic MAPK signaling R-HSA-6802957
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
FCGR3A-mediated phagocytosis R-HSA-9664422
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by RAF1 mutants R-HSA-9656223
Signaling by FGFR4 R-HSA-5654743
Leishmania infection R-HSA-9658195
Spry regulation of FGF signaling R-HSA-1295596
Generic Transcription Pathway R-HSA-212436
Recycling pathway of L1 R-HSA-437239
Interleukin-17 signaling R-HSA-448424
ESR-mediated signaling R-HSA-8939211
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Negative regulation of the PI3K/AKT network R-HSA-199418
Regulation of PTEN gene transcription R-HSA-8943724
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Cellular response to heat stress R-HSA-3371556
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll-like Receptor Cascades R-HSA-168898
Apoptotic factor-mediated response R-HSA-111471
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Infectious disease R-HSA-5663205
Signaling by Activin R-HSA-1502540
MAPK family signaling cascades R-HSA-5683057
Signaling by ALK in cancer R-HSA-9700206
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Negative regulation of MAPK pathway R-HSA-5675221
Frs2-mediated activation R-HSA-170968
RSK activation R-HSA-444257
Intracellular signaling by second messengers R-HSA-9006925
Programmed Cell Death R-HSA-5357801
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Apoptosis R-HSA-109581
Signalling to ERKs R-HSA-187687
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
L1CAM interactions R-HSA-373760
Parasite infection R-HSA-9664407
Prolonged ERK activation events R-HSA-169893
Extra-nuclear estrogen signaling R-HSA-9009391
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Signaling by FGFR2 R-HSA-5654738
Platelet activation, signaling and aggregation R-HSA-76002
Axon guidance R-HSA-422475
Disease R-HSA-1643685
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Oxidative Stress Induced Senescence R-HSA-2559580
Suppression of apoptosis R-HSA-9635465
Signaling by NODAL R-HSA-1181150
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Signaling by Nuclear Receptors R-HSA-9006931
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Leishmania phagocytosis R-HSA-9664417
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
PTEN Regulation R-HSA-6807070
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cellular responses to stress R-HSA-2262752
Signal transduction by L1 R-HSA-445144
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
GPCR downstream signalling R-HSA-388396
Cytochrome c-mediated apoptotic response R-HSA-111461
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Nervous system development R-HSA-9675108
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Neuronal System R-HSA-112316
Transcriptional Regulation by NPAS4 R-HSA-9634815
RUNX2 regulates bone development R-HSA-8941326
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by TGF-beta Receptor Complex R-HSA-170834
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Transmission across Chemical Synapses R-HSA-112315
Mitotic Prophase R-HSA-68875
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signaling by NTRKs R-HSA-166520
Transcriptional regulation by RUNX2 R-HSA-8878166
Intrinsic Pathway for Apoptosis R-HSA-109606
Signal attenuation R-HSA-74749
Negative regulation of FGFR3 signaling R-HSA-5654732
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
phospho-PLA2 pathway R-HSA-111995
MAP kinase activation R-HSA-450294
Signaling by NTRK1 (TRKA) R-HSA-187037
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by FGFR R-HSA-190236
G alpha (i) signalling events R-HSA-418594
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
MAPK1 (ERK2) activation R-HSA-112411
Signaling by TGFB family members R-HSA-9006936
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
M Phase R-HSA-68886
ERK/MAPK targets R-HSA-198753
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Negative regulation of FGFR2 signaling R-HSA-5654727
RHO GTPase Effectors R-HSA-195258
Developmental Biology R-HSA-1266738
Oncogenic MAPK signaling R-HSA-6802957
Signaling by FGFR1 R-HSA-5654736
Signal Transduction R-HSA-162582
Regulation of PTEN gene transcription R-HSA-8943724
MAPK1 (ERK2) activation R-HSA-112411
Negative regulation of MAPK pathway R-HSA-5675221
MyD88 cascade initiated on plasma membrane R-HSA-975871
Ca-dependent events R-HSA-111996
Neutrophil degranulation R-HSA-6798695
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Insulin receptor signalling cascade R-HSA-74751
MAPK family signaling cascades R-HSA-5683057
Signaling by Rho GTPases R-HSA-194315
MAP kinase activation R-HSA-450294
Signaling by FGFR2 R-HSA-5654738
Transcriptional regulation by RUNX2 R-HSA-8878166
Leishmania infection R-HSA-9658195
RSK activation R-HSA-444257
Signaling by NTRKs R-HSA-166520
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Cellular response to heat stress R-HSA-3371556
Signaling by NODAL R-HSA-1181150
Negative feedback regulation of MAPK pathway R-HSA-5674499
Gene expression (Transcription) R-HSA-74160
Cell Cycle, Mitotic R-HSA-69278
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FGFR4 R-HSA-5654743
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by Insulin receptor R-HSA-74752
L1CAM interactions R-HSA-373760
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Intracellular signaling by second messengers R-HSA-9006925
MyD88-independent TLR4 cascade R-HSA-166166
Intrinsic Pathway for Apoptosis R-HSA-109606
FCERI mediated MAPK activation R-HSA-2871796
Cellular responses to stress R-HSA-2262752
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
NCAM signaling for neurite out-growth R-HSA-375165
Apoptosis R-HSA-109581
Signaling by FGFR3 R-HSA-5654741
Signaling by RAS mutants R-HSA-6802949
Growth hormone receptor signaling R-HSA-982772
RNA Polymerase II Transcription R-HSA-73857
Leishmania phagocytosis R-HSA-9664417
Interleukin-17 signaling R-HSA-448424
Apoptotic factor-mediated response R-HSA-111471
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Frs2-mediated activation R-HSA-170968
Cell Cycle R-HSA-1640170
Signaling by NTRK1 (TRKA) R-HSA-187037
ESR-mediated signaling R-HSA-8939211
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Transmission across Chemical Synapses R-HSA-112315
Signaling downstream of RAS mutants R-HSA-9649948
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Prolonged ERK activation events R-HSA-169893
Regulation of the apoptosome activity R-HSA-9627069
Cellular responses to stimuli R-HSA-8953897
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Signaling by FGFR R-HSA-190236
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Extra-nuclear estrogen signaling R-HSA-9009391
Infection with Mycobacterium tuberculosis R-HSA-9635486
G alpha (q) signalling events R-HSA-416476
Opioid Signalling R-HSA-111885
Negative regulation of FGFR3 signaling R-HSA-5654732
Signal transduction by L1 R-HSA-445144
Suppression of apoptosis R-HSA-9635465
Activation of the AP-1 family of transcription factors R-HSA-450341
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
MAPK1/MAPK3 signaling R-HSA-5684996
Generic Transcription Pathway R-HSA-212436
Signaling by Interleukins R-HSA-449147
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Programmed Cell Death R-HSA-5357801
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signalling to ERKs R-HSA-187687
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Disease R-HSA-1643685
phospho-PLA2 pathway R-HSA-111995
GPCR downstream signalling R-HSA-388396
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Mitotic Prophase R-HSA-68875
Immune System R-HSA-168256
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Platelet activation, signaling and aggregation R-HSA-76002
Spry regulation of FGF signaling R-HSA-1295596
Signaling by MAPK mutants R-HSA-9652817
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RUNX2 regulates bone development R-HSA-8941326
Cytokine Signaling in Immune system R-HSA-1280215
Infectious disease R-HSA-5663205
NPAS4 regulates expression of target genes R-HSA-9768919
Response of Mtb to phagocytosis R-HSA-9637690
ERKs are inactivated R-HSA-202670
Negative regulation of FGFR1 signaling R-HSA-5654726
MyD88 dependent cascade initiated on endosome R-HSA-975155
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Innate Immune System R-HSA-168249
Transcriptional Regulation by NPAS4 R-HSA-9634815
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Neuronal System R-HSA-112316
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Axon guidance R-HSA-422475
Cellular Senescence R-HSA-2559583
PIP3 activates AKT signaling R-HSA-1257604
G-protein mediated events R-HSA-112040
Signaling by TGFB family members R-HSA-9006936
Formation of apoptosome R-HSA-111458
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by RAF1 mutants R-HSA-9656223
Signaling by TGF-beta Receptor Complex R-HSA-170834
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Activin R-HSA-1502540
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Parasite infection R-HSA-9664407
Signaling by MAP2K mutants R-HSA-9652169
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Signaling by ALK in cancer R-HSA-9700206
FCGR3A-mediated phagocytosis R-HSA-9664422
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Negative regulation of the PI3K/AKT network R-HSA-199418
MAP2K and MAPK activation R-HSA-5674135
Signal attenuation R-HSA-74749
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Cytochrome c-mediated apoptotic response R-HSA-111461
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by Nuclear Receptors R-HSA-9006931
Hemostasis R-HSA-109582
G alpha (i) signalling events R-HSA-418594
RAF/MAP kinase cascade R-HSA-5673001
Toll-like Receptor Cascades R-HSA-168898
Post NMDA receptor activation events R-HSA-438064
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Oncogene Induced Senescence R-HSA-2559585
PLC beta mediated events R-HSA-112043
Signaling by GPCR R-HSA-372790
M Phase R-HSA-68886
Recycling pathway of L1 R-HSA-437239
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
PTEN Regulation R-HSA-6807070
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Hemostasis R-HSA-109582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
ERKs are inactivated R-HSA-202670
Neuronal System R-HSA-112316
Neutrophil degranulation R-HSA-6798695
MyD88-independent TLR4 cascade R-HSA-166166
Negative regulation of FGFR1 signaling R-HSA-5654726
Toll-like Receptor Cascades R-HSA-168898
Signaling by TGF-beta Receptor Complex R-HSA-170834
M Phase R-HSA-68886
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Negative regulation of FGFR4 signaling R-HSA-5654733
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Disease R-HSA-1643685
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Negative regulation of the PI3K/AKT network R-HSA-199418
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by NTRKs R-HSA-166520
Cellular Senescence R-HSA-2559583
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK family signaling cascades R-HSA-5683057
Cytochrome c-mediated apoptotic response R-HSA-111461
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by TGFB family members R-HSA-9006936
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Cellular response to heat stress R-HSA-3371556
Insulin receptor signalling cascade R-HSA-74751
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Transmission across Chemical Synapses R-HSA-112315
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Axon guidance R-HSA-422475
FCERI mediated MAPK activation R-HSA-2871796
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Spry regulation of FGF signaling R-HSA-1295596
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by FGFR3 R-HSA-5654741
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Extra-nuclear estrogen signaling R-HSA-9009391
Leishmania infection R-HSA-9658195
Oncogenic MAPK signaling R-HSA-6802957
RAF/MAP kinase cascade R-HSA-5673001
PLC beta mediated events R-HSA-112043
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Infection with Mycobacterium tuberculosis R-HSA-9635486
ERK/MAPK targets R-HSA-198753
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Signal attenuation R-HSA-74749
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by FGFR1 R-HSA-5654736
RHO GTPase Effectors R-HSA-195258
Transcriptional regulation by RUNX2 R-HSA-8878166
Signal transduction by L1 R-HSA-445144
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Mitotic Prophase R-HSA-68875
Growth hormone receptor signaling R-HSA-982772
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ca-dependent events R-HSA-111996
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by RAF1 mutants R-HSA-9656223
Leishmania phagocytosis R-HSA-9664417
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
RUNX2 regulates bone development R-HSA-8941326
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Interleukins R-HSA-449147
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by NODAL R-HSA-1181150
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Apoptotic factor-mediated response R-HSA-111471
Gene expression (Transcription) R-HSA-74160
phospho-PLA2 pathway R-HSA-111995
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Nervous system development R-HSA-9675108
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stress R-HSA-2262752
Intracellular signaling by second messengers R-HSA-9006925
Regulation of the apoptosome activity R-HSA-9627069
Suppression of apoptosis R-HSA-9635465
Cell Cycle R-HSA-1640170
Oncogene Induced Senescence R-HSA-2559585
Recycling pathway of L1 R-HSA-437239
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by MAPK mutants R-HSA-9652817
Signaling by FGFR2 R-HSA-5654738
RNA Polymerase II Transcription R-HSA-73857
GPCR downstream signalling R-HSA-388396
Signaling by MAP2K mutants R-HSA-9652169
MyD88 cascade initiated on plasma membrane R-HSA-975871
MyD88 dependent cascade initiated on endosome R-HSA-975155
Parasite infection R-HSA-9664407
PTEN Regulation R-HSA-6807070
Frs2-mediated activation R-HSA-170968
RAF-independent MAPK1/3 activation R-HSA-112409
Post NMDA receptor activation events R-HSA-438064
Signaling by Nuclear Receptors R-HSA-9006931
NPAS4 regulates expression of target genes R-HSA-9768919
RSK activation R-HSA-444257
G alpha (i) signalling events R-HSA-418594
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by FGFR R-HSA-190236
Response of Mtb to phagocytosis R-HSA-9637690
Programmed Cell Death R-HSA-5357801
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by FGFR4 R-HSA-5654743
Signaling by Rho GTPases R-HSA-194315
Signaling by GPCR R-HSA-372790
Negative regulation of FGFR3 signaling R-HSA-5654732
G alpha (q) signalling events R-HSA-416476
Signalling to ERKs R-HSA-187687
Signaling by Insulin receptor R-HSA-74752
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAP2K and MAPK activation R-HSA-5674135
Signaling by Activin R-HSA-1502540
Infectious disease R-HSA-5663205
ESR-mediated signaling R-HSA-8939211
L1CAM interactions R-HSA-373760
Negative regulation of MAPK pathway R-HSA-5675221
Opioid Signalling R-HSA-111885
Innate Immune System R-HSA-168249
Activation of NMDA receptors and postsynaptic events R-HSA-442755
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
G-protein mediated events R-HSA-112040
Immune System R-HSA-168256
Cell Cycle, Mitotic R-HSA-69278
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Apoptosis R-HSA-109581
Developmental Biology R-HSA-1266738
MAP kinase activation R-HSA-450294
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulation of HSF1-mediated heat shock response R-HSA-3371453
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Platelet activation, signaling and aggregation R-HSA-76002
MAPK1 (ERK2) activation R-HSA-112411
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Formation of apoptosome R-HSA-111458
Signaling by ALK in cancer R-HSA-9700206
Prolonged ERK activation events R-HSA-169893
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling downstream of RAS mutants R-HSA-9649948
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Negative regulation of FGFR2 signaling R-HSA-5654727
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by RAS mutants R-HSA-6802949

Expression Atlas ENSG00000100030
LRG display in Ensembl gene LRG_786
NCBI gene (formerly Entrezgene) 5594
GeneCards 6871
HGNC Symbol HGNC:6871
MIM gene 176948
MIM morbid 619087
UniProtKB Gene Name Q1HBJ4
WikiGene 5594
Gene: KDR
Ensembl ID : ENSG00000128052
Description: kinase insert domain receptor
Gene Synonyms: CD309,FLK1,VEGFR,VEGFR2
71 APIs:
199 Possible Orthologues:

VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by VEGF R-HSA-194138
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGF ligand-receptor interactions R-HSA-194313
Extracellular matrix organization R-HSA-1474244
VEGFA-VEGFR2 Pathway R-HSA-4420097
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Integrin cell surface interactions R-HSA-216083
Signaling by PDGFR in disease R-HSA-9671555
Integrin cell surface interactions R-HSA-216083
VEGFR2 mediated cell proliferation R-HSA-5218921
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGFA-VEGFR2 Pathway R-HSA-4420097
Disease R-HSA-1643685
Extracellular matrix organization R-HSA-1474244
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
Signaling by PDGFR in disease R-HSA-9671555
Signal Transduction R-HSA-162582
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFA-VEGFR2 Pathway R-HSA-4420097
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by VEGF R-HSA-194138
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
VEGF ligand-receptor interactions R-HSA-194313
Signaling by PDGFR in disease R-HSA-9671555
Signal Transduction R-HSA-162582
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGFR2 mediated cell proliferation R-HSA-5218921
Integrin cell surface interactions R-HSA-216083
Extracellular matrix organization R-HSA-1474244
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by VEGF R-HSA-194138
VEGFA-VEGFR2 Pathway R-HSA-4420097
Integrin cell surface interactions R-HSA-216083
VEGF ligand-receptor interactions R-HSA-194313
Extracellular matrix organization R-HSA-1474244
Disease R-HSA-1643685
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signal Transduction R-HSA-162582
Signaling by PDGFR in disease R-HSA-9671555
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signal Transduction R-HSA-162582
VEGFA-VEGFR2 Pathway R-HSA-4420097
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Integrin cell surface interactions R-HSA-216083
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGFR in disease R-HSA-9671555
VEGF ligand-receptor interactions R-HSA-194313
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signaling by VEGF R-HSA-194138
Extracellular matrix organization R-HSA-1474244
Signaling by VEGF R-HSA-194138
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signal Transduction R-HSA-162582
VEGFR2 mediated cell proliferation R-HSA-5218921
Integrin cell surface interactions R-HSA-216083
Signaling by PDGFR in disease R-HSA-9671555
Extracellular matrix organization R-HSA-1474244
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGFA-VEGFR2 Pathway R-HSA-4420097
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Disease R-HSA-1643685
Integrin cell surface interactions R-HSA-216083
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGFR2 mediated cell proliferation R-HSA-5218921
Extracellular matrix organization R-HSA-1474244
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signaling by VEGF R-HSA-194138
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGFR in disease R-HSA-9671555
VEGF ligand-receptor interactions R-HSA-194313
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGFA-VEGFR2 Pathway R-HSA-4420097
Integrin cell surface interactions R-HSA-216083
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by PDGFR in disease R-HSA-9671555
VEGF ligand-receptor interactions R-HSA-194313
Signaling by VEGF R-HSA-194138
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
VEGFR2 mediated cell proliferation R-HSA-5218921
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGFA-VEGFR2 Pathway R-HSA-4420097
Extracellular matrix organization R-HSA-1474244
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
VEGF ligand-receptor interactions R-HSA-194313
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGFR2 mediated cell proliferation R-HSA-5218921
Integrin cell surface interactions R-HSA-216083
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
Extracellular matrix organization R-HSA-1474244
Signaling by PDGFR in disease R-HSA-9671555
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
VEGFA-VEGFR2 Pathway R-HSA-4420097
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFR2 mediated cell proliferation R-HSA-5218921
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signaling by PDGFR in disease R-HSA-9671555
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by VEGF R-HSA-194138
Integrin cell surface interactions R-HSA-216083
VEGF ligand-receptor interactions R-HSA-194313
Extracellular matrix organization R-HSA-1474244
Disease R-HSA-1643685

Expression Atlas ENSG00000128052
LRG display in Ensembl gene LRG_1198
NCBI gene (formerly Entrezgene) 3791
GeneCards 6307
HGNC Symbol HGNC:6307
MIM gene 191306
MIM morbid 602089
UniProtKB Gene Name P35968
WikiGene 3791
Gene: IKBKB
Ensembl ID : ENSG00000104365
Description: inhibitor of nuclear factor kappa B kinase subunit beta
Gene Synonyms: IKK-BETA,IKK2,IKKB,NFKBIKB
7 APIs:
197 Possible Orthologues:

Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Diseases of Immune System R-HSA-5260271
TCR signaling R-HSA-202403
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
p75NTR recruits signalling complexes R-HSA-209543
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Diseases associated with the TLR signaling cascade R-HSA-5602358
Regulation of NF-kappa B signaling R-HSA-9758274
C-type lectin receptors (CLRs) R-HSA-5621481
TRAF6 mediated NF-kB activation R-HSA-933542
MyD88 cascade initiated on plasma membrane R-HSA-975871
p75NTR signals via NF-kB R-HSA-193639
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Signaling by the B Cell Receptor (BCR) R-HSA-983705
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
ER-Phagosome pathway R-HSA-1236974
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88 dependent cascade initiated on endosome R-HSA-975155
NOD1/2 Signaling Pathway R-HSA-168638
p75 NTR receptor-mediated signalling R-HSA-193704
IkBA variant leads to EDA-ID R-HSA-5603029
Activation of NF-kappaB in B cells R-HSA-1169091
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
MAP kinase activation R-HSA-450294
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
MyD88-independent TLR4 cascade R-HSA-166166
FCERI mediated NF-kB activation R-HSA-2871837
IKBKB deficiency causes SCID R-HSA-5602636
Immune System R-HSA-168256
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Interleukin-1 family signaling R-HSA-446652
SARS-CoV Infections R-HSA-9679506
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by Interleukins R-HSA-449147
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TNF signaling R-HSA-75893
CLEC7A (Dectin-1) signaling R-HSA-5607764
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
SARS-CoV-2 Infection R-HSA-9694516
NF-kB is activated and signals survival R-HSA-209560
Innate Immune System R-HSA-168249
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-1 signaling R-HSA-9020702
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Antigen processing-Cross presentation R-HSA-1236975
Downstream TCR signaling R-HSA-202424
Signal Transduction R-HSA-162582
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Toll-like Receptor Cascades R-HSA-168898
IKK complex recruitment mediated by RIP1 R-HSA-937041
Disease R-HSA-1643685
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
SARS-CoV-2-host interactions R-HSA-9705683
Cytokine Signaling in Immune system R-HSA-1280215
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
IRAK1 recruits IKK complex R-HSA-937039
Regulation of TNFR1 signaling R-HSA-5357905
MyD88 cascade initiated on plasma membrane R-HSA-975871
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
MyD88 dependent cascade initiated on endosome R-HSA-975155
IKK complex recruitment mediated by RIP1 R-HSA-937041
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
Interleukin-1 family signaling R-HSA-446652
Infectious disease R-HSA-5663205
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signal Transduction R-HSA-162582
ER-Phagosome pathway R-HSA-1236974
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of TNFR1 signaling R-HSA-5357905
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
IKBKB deficiency causes SCID R-HSA-5602636
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Interleukins R-HSA-449147
TRAF6 mediated NF-kB activation R-HSA-933542
MAP kinase activation R-HSA-450294
Innate Immune System R-HSA-168249
Interleukin-17 signaling R-HSA-448424
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MyD88-independent TLR4 cascade R-HSA-166166
C-type lectin receptors (CLRs) R-HSA-5621481
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
IkBA variant leads to EDA-ID R-HSA-5603029
Death Receptor Signaling R-HSA-73887
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
SARS-CoV Infections R-HSA-9679506
NF-kB is activated and signals survival R-HSA-209560
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
IRAK1 recruits IKK complex R-HSA-937039
p75NTR recruits signalling complexes R-HSA-209543
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Diseases of Immune System R-HSA-5260271
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
NOD1/2 Signaling Pathway R-HSA-168638
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Immune System R-HSA-168256
SARS-CoV-2 Infection R-HSA-9694516
TCR signaling R-HSA-202403
Activation of NF-kappaB in B cells R-HSA-1169091
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Diseases associated with the TLR signaling cascade R-HSA-5602358
Disease R-HSA-1643685
p75NTR signals via NF-kB R-HSA-193639
TNF signaling R-HSA-75893
Antigen processing-Cross presentation R-HSA-1236975
Downstream TCR signaling R-HSA-202424
SARS-CoV-2-host interactions R-HSA-9705683
Regulation of NF-kappa B signaling R-HSA-9758274
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
FCERI mediated NF-kB activation R-HSA-2871837
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
p75 NTR receptor-mediated signalling R-HSA-193704
Interleukin-1 signaling R-HSA-9020702
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
Toll-like Receptor Cascades R-HSA-168898
Immune System R-HSA-168256
Downstream TCR signaling R-HSA-202424
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Interleukin-1 family signaling R-HSA-446652
MyD88 dependent cascade initiated on endosome R-HSA-975155
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
NOD1/2 Signaling Pathway R-HSA-168638
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MAP kinase activation R-HSA-450294
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by Interleukins R-HSA-449147
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
FCERI mediated NF-kB activation R-HSA-2871837
C-type lectin receptors (CLRs) R-HSA-5621481
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
SARS-CoV Infections R-HSA-9679506
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Diseases associated with the TLR signaling cascade R-HSA-5602358
MyD88 cascade initiated on plasma membrane R-HSA-975871
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
TCR signaling R-HSA-202403
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
IkBA variant leads to EDA-ID R-HSA-5603029
p75NTR signals via NF-kB R-HSA-193639
p75 NTR receptor-mediated signalling R-HSA-193704
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
Diseases of Immune System R-HSA-5260271
IRAK1 recruits IKK complex R-HSA-937039
Activation of NF-kappaB in B cells R-HSA-1169091
ER-Phagosome pathway R-HSA-1236974
SARS-CoV-2 Infection R-HSA-9694516
TRAF6 mediated NF-kB activation R-HSA-933542
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Regulation of TNFR1 signaling R-HSA-5357905
Interleukin-17 signaling R-HSA-448424
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
NF-kB is activated and signals survival R-HSA-209560
MyD88-independent TLR4 cascade R-HSA-166166
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
IKBKB deficiency causes SCID R-HSA-5602636
Cytokine Signaling in Immune system R-HSA-1280215
TNF signaling R-HSA-75893
Signal Transduction R-HSA-162582
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Antigen processing-Cross presentation R-HSA-1236975
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Class I MHC mediated antigen processing & presentation R-HSA-983169
p75NTR recruits signalling complexes R-HSA-209543
SARS-CoV-2-host interactions R-HSA-9705683
IKK complex recruitment mediated by RIP1 R-HSA-937041
SARS-CoV-2 Infection R-HSA-9694516
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
SARS-CoV-2-host interactions R-HSA-9705683
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Disease R-HSA-1643685
IKBKB deficiency causes SCID R-HSA-5602636
p75 NTR receptor-mediated signalling R-HSA-193704
MyD88 cascade initiated on plasma membrane R-HSA-975871
p75NTR signals via NF-kB R-HSA-193639
Diseases of Immune System R-HSA-5260271
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p75NTR recruits signalling complexes R-HSA-209543
TNF signaling R-HSA-75893
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
SARS-CoV Infections R-HSA-9679506
Interleukin-1 family signaling R-HSA-446652
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
MAP kinase activation R-HSA-450294
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Antigen processing-Cross presentation R-HSA-1236975
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
C-type lectin receptors (CLRs) R-HSA-5621481
TRAF6 mediated NF-kB activation R-HSA-933542
Downstream TCR signaling R-HSA-202424
MyD88 dependent cascade initiated on endosome R-HSA-975155
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Class I MHC mediated antigen processing & presentation R-HSA-983169
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
ER-Phagosome pathway R-HSA-1236974
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
FCERI mediated NF-kB activation R-HSA-2871837
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Adaptive Immune System R-HSA-1280218
Diseases associated with the TLR signaling cascade R-HSA-5602358
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
NOD1/2 Signaling Pathway R-HSA-168638
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Infectious disease R-HSA-5663205
IRAK1 recruits IKK complex R-HSA-937039
TCR signaling R-HSA-202403
Activation of NF-kappaB in B cells R-HSA-1169091
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Regulation of TNFR1 signaling R-HSA-5357905
Signaling by Interleukins R-HSA-449147
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll-like Receptor Cascades R-HSA-168898
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
NF-kB is activated and signals survival R-HSA-209560
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88-independent TLR4 cascade R-HSA-166166
IKK complex recruitment mediated by RIP1 R-HSA-937041
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
IkBA variant leads to EDA-ID R-HSA-5603029
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Interleukin-1 signaling R-HSA-9020702
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Adaptive Immune System R-HSA-1280218
TNF signaling R-HSA-75893
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
IKBKB deficiency causes SCID R-HSA-5602636
Immune System R-HSA-168256
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
TRAF6 mediated NF-kB activation R-HSA-933542
Regulation of TNFR1 signaling R-HSA-5357905
Antigen processing-Cross presentation R-HSA-1236975
SARS-CoV-2 Infection R-HSA-9694516
MyD88 dependent cascade initiated on endosome R-HSA-975155
Class I MHC mediated antigen processing & presentation R-HSA-983169
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Diseases associated with the TLR signaling cascade R-HSA-5602358
Toll-like Receptor Cascades R-HSA-168898
FCERI mediated NF-kB activation R-HSA-2871837
IRAK1 recruits IKK complex R-HSA-937039
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ER-Phagosome pathway R-HSA-1236974
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
TCR signaling R-HSA-202403
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
p75 NTR receptor-mediated signalling R-HSA-193704
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
NF-kB is activated and signals survival R-HSA-209560
Activation of NF-kappaB in B cells R-HSA-1169091
NOD1/2 Signaling Pathway R-HSA-168638
IKK complex recruitment mediated by RIP1 R-HSA-937041
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Diseases of Immune System R-HSA-5260271
MAP kinase activation R-HSA-450294
p75NTR recruits signalling complexes R-HSA-209543
p75NTR signals via NF-kB R-HSA-193639
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88-independent TLR4 cascade R-HSA-166166
CLEC7A (Dectin-1) signaling R-HSA-5607764
SARS-CoV Infections R-HSA-9679506
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Infectious disease R-HSA-5663205
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Death Receptor Signaling R-HSA-73887
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Downstream TCR signaling R-HSA-202424
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
SARS-CoV-2-host interactions R-HSA-9705683
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-17 signaling R-HSA-448424
Interleukin-1 family signaling R-HSA-446652
Regulation of NF-kappa B signaling R-HSA-9758274
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
IkBA variant leads to EDA-ID R-HSA-5603029
MyD88 cascade initiated on plasma membrane R-HSA-975871
Class I MHC mediated antigen processing & presentation R-HSA-983169
IRAK1 recruits IKK complex R-HSA-937039
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Interleukin-17 signaling R-HSA-448424
IkBA variant leads to EDA-ID R-HSA-5603029
MyD88 dependent cascade initiated on endosome R-HSA-975155
p75NTR recruits signalling complexes R-HSA-209543
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Diseases of Immune System R-HSA-5260271
IKK complex recruitment mediated by RIP1 R-HSA-937041
Diseases associated with the TLR signaling cascade R-HSA-5602358
Innate Immune System R-HSA-168249
MyD88 cascade initiated on plasma membrane R-HSA-975871
FCERI mediated NF-kB activation R-HSA-2871837
C-type lectin receptors (CLRs) R-HSA-5621481
Death Receptor Signaling R-HSA-73887
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of NF-kappa B signaling R-HSA-9758274
Antigen processing-Cross presentation R-HSA-1236975
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Interleukin-1 signaling R-HSA-9020702
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
MyD88-independent TLR4 cascade R-HSA-166166
NOD1/2 Signaling Pathway R-HSA-168638
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-1 family signaling R-HSA-446652
Cytokine Signaling in Immune system R-HSA-1280215
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
NF-kB is activated and signals survival R-HSA-209560
Activation of NF-kappaB in B cells R-HSA-1169091
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
IKBKB deficiency causes SCID R-HSA-5602636
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by Interleukins R-HSA-449147
Downstream TCR signaling R-HSA-202424
SARS-CoV-2-host interactions R-HSA-9705683
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p75NTR signals via NF-kB R-HSA-193639
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Infectious disease R-HSA-5663205
SARS-CoV-2 Infection R-HSA-9694516
ER-Phagosome pathway R-HSA-1236974
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
MAP kinase activation R-HSA-450294
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TNF signaling R-HSA-75893
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Immune System R-HSA-168256
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
SARS-CoV Infections R-HSA-9679506
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
TCR signaling R-HSA-202403
TRAF6 mediated NF-kB activation R-HSA-933542
Signal Transduction R-HSA-162582
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Interleukin-1 family signaling R-HSA-446652
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
NF-kB is activated and signals survival R-HSA-209560
Diseases of Immune System R-HSA-5260271
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Interleukin-1 signaling R-HSA-9020702
Activation of NF-kappaB in B cells R-HSA-1169091
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Interleukin-17 signaling R-HSA-448424
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TCR signaling R-HSA-202403
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
SARS-CoV-2 Infection R-HSA-9694516
MyD88 dependent cascade initiated on endosome R-HSA-975155
Diseases associated with the TLR signaling cascade R-HSA-5602358
p75NTR recruits signalling complexes R-HSA-209543
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
p75 NTR receptor-mediated signalling R-HSA-193704
Class I MHC mediated antigen processing & presentation R-HSA-983169
IKK complex recruitment mediated by RIP1 R-HSA-937041
Infectious disease R-HSA-5663205
ER-Phagosome pathway R-HSA-1236974
FCERI mediated NF-kB activation R-HSA-2871837
TNF signaling R-HSA-75893
Antigen processing-Cross presentation R-HSA-1236975
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
p75NTR signals via NF-kB R-HSA-193639
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
IkBA variant leads to EDA-ID R-HSA-5603029
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Disease R-HSA-1643685
CLEC7A (Dectin-1) signaling R-HSA-5607764
SARS-CoV Infections R-HSA-9679506
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Regulation of NF-kappa B signaling R-HSA-9758274
SARS-CoV-2-host interactions R-HSA-9705683
MyD88-independent TLR4 cascade R-HSA-166166
IKBKB deficiency causes SCID R-HSA-5602636
IRAK1 recruits IKK complex R-HSA-937039
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Innate Immune System R-HSA-168249
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Downstream TCR signaling R-HSA-202424
Adaptive Immune System R-HSA-1280218
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Death Receptor Signaling R-HSA-73887
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
NOD1/2 Signaling Pathway R-HSA-168638
MyD88 cascade initiated on plasma membrane R-HSA-975871
Immune System R-HSA-168256
Toll-like Receptor Cascades R-HSA-168898
Regulation of TNFR1 signaling R-HSA-5357905
TRAF6 mediated NF-kB activation R-HSA-933542
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
C-type lectin receptors (CLRs) R-HSA-5621481
MAP kinase activation R-HSA-450294
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Innate Immune System R-HSA-168249
Death Receptor Signaling R-HSA-73887
NOD1/2 Signaling Pathway R-HSA-168638
Interleukin-1 family signaling R-HSA-446652
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
Interleukin-1 signaling R-HSA-9020702
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Activation of NF-kappaB in B cells R-HSA-1169091
p75NTR signals via NF-kB R-HSA-193639
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
Signaling by Interleukins R-HSA-449147
p75NTR recruits signalling complexes R-HSA-209543
Diseases associated with the TLR signaling cascade R-HSA-5602358
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
IKK complex recruitment mediated by RIP1 R-HSA-937041
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
MAP kinase activation R-HSA-450294
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Class I MHC mediated antigen processing & presentation R-HSA-983169
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Signal Transduction R-HSA-162582
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
C-type lectin receptors (CLRs) R-HSA-5621481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
IkBA variant leads to EDA-ID R-HSA-5603029
Interleukin-17 signaling R-HSA-448424
FCERI mediated NF-kB activation R-HSA-2871837
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88 dependent cascade initiated on endosome R-HSA-975155
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Toll-like Receptor Cascades R-HSA-168898
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Diseases of Immune System R-HSA-5260271
Downstream TCR signaling R-HSA-202424
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Regulation of NF-kappa B signaling R-HSA-9758274
SARS-CoV-2-host interactions R-HSA-9705683
SARS-CoV Infections R-HSA-9679506
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
SARS-CoV-2 Infection R-HSA-9694516
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Adaptive Immune System R-HSA-1280218
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TCR signaling R-HSA-202403
Regulation of TNFR1 signaling R-HSA-5357905
Antigen processing-Cross presentation R-HSA-1236975
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
NF-kB is activated and signals survival R-HSA-209560
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
IKBKB deficiency causes SCID R-HSA-5602636
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
p75 NTR receptor-mediated signalling R-HSA-193704
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
CLEC7A (Dectin-1) signaling R-HSA-5607764
TNF signaling R-HSA-75893
Infectious disease R-HSA-5663205
IRAK1 recruits IKK complex R-HSA-937039
TRAF6 mediated NF-kB activation R-HSA-933542
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Immune System R-HSA-168256
ER-Phagosome pathway R-HSA-1236974
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Disease R-HSA-1643685
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
CLEC7A (Dectin-1) signaling R-HSA-5607764
IkBA variant leads to EDA-ID R-HSA-5603029
Interleukin-1 family signaling R-HSA-446652
C-type lectin receptors (CLRs) R-HSA-5621481
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
p75NTR recruits signalling complexes R-HSA-209543
Diseases associated with the TLR signaling cascade R-HSA-5602358
p75NTR signals via NF-kB R-HSA-193639
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Antigen processing-Cross presentation R-HSA-1236975
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
NF-kB is activated and signals survival R-HSA-209560
Signaling by Interleukins R-HSA-449147
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cytokine Signaling in Immune system R-HSA-1280215
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
IRAK1 recruits IKK complex R-HSA-937039
SARS-CoV-2 Infection R-HSA-9694516
IKK complex recruitment mediated by RIP1 R-HSA-937041
Class I MHC mediated antigen processing & presentation R-HSA-983169
Downstream TCR signaling R-HSA-202424
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
NOD1/2 Signaling Pathway R-HSA-168638
Adaptive Immune System R-HSA-1280218
MyD88 dependent cascade initiated on endosome R-HSA-975155
Death Receptor Signaling R-HSA-73887
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Infectious disease R-HSA-5663205
Activation of NF-kappaB in B cells R-HSA-1169091
TRAF6 mediated NF-kB activation R-HSA-933542
Interleukin-17 signaling R-HSA-448424
TCR signaling R-HSA-202403
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulation of TNFR1 signaling R-HSA-5357905
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Innate Immune System R-HSA-168249
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Disease R-HSA-1643685
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Diseases of Immune System R-HSA-5260271
MAP kinase activation R-HSA-450294
Toll-like Receptor Cascades R-HSA-168898
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Immune System R-HSA-168256
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Regulation of NF-kappa B signaling R-HSA-9758274
TNF signaling R-HSA-75893
Interleukin-1 signaling R-HSA-9020702
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
SARS-CoV Infections R-HSA-9679506
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
SARS-CoV-2-host interactions R-HSA-9705683
Signal Transduction R-HSA-162582
p75 NTR receptor-mediated signalling R-HSA-193704
IKBKB deficiency causes SCID R-HSA-5602636
ER-Phagosome pathway R-HSA-1236974
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Infectious disease R-HSA-5663205
IKK complex recruitment mediated by RIP1 R-HSA-937041
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of NF-kappa B signaling R-HSA-9758274
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
TNF signaling R-HSA-75893
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
Disease R-HSA-1643685
Signaling by Interleukins R-HSA-449147
IkBA variant leads to EDA-ID R-HSA-5603029
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
ER-Phagosome pathway R-HSA-1236974
Diseases associated with the TLR signaling cascade R-HSA-5602358
Regulation of TNFR1 signaling R-HSA-5357905
SARS-CoV Infections R-HSA-9679506
FCERI mediated NF-kB activation R-HSA-2871837
NOD1/2 Signaling Pathway R-HSA-168638
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Death Receptor Signaling R-HSA-73887
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
IKBKB deficiency causes SCID R-HSA-5602636
Toll-like Receptor Cascades R-HSA-168898
NF-kB is activated and signals survival R-HSA-209560
Interleukin-1 signaling R-HSA-9020702
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Class I MHC mediated antigen processing & presentation R-HSA-983169
Diseases of Immune System R-HSA-5260271
Innate Immune System R-HSA-168249
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Immune System R-HSA-168256
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
SARS-CoV-2-host interactions R-HSA-9705683
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
TCR signaling R-HSA-202403
p75NTR recruits signalling complexes R-HSA-209543
SARS-CoV-2 Infection R-HSA-9694516
Signal Transduction R-HSA-162582
CLEC7A (Dectin-1) signaling R-HSA-5607764
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Interleukin-1 family signaling R-HSA-446652
MyD88 dependent cascade initiated on endosome R-HSA-975155
Interleukin-17 signaling R-HSA-448424
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Downstream TCR signaling R-HSA-202424
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
MyD88-independent TLR4 cascade R-HSA-166166
Adaptive Immune System R-HSA-1280218
MAP kinase activation R-HSA-450294
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
p75NTR signals via NF-kB R-HSA-193639
C-type lectin receptors (CLRs) R-HSA-5621481
Antigen processing-Cross presentation R-HSA-1236975
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
IRAK1 recruits IKK complex R-HSA-937039
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Regulation of NF-kappa B signaling R-HSA-9758274
Activation of NF-kappaB in B cells R-HSA-1169091
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
IkBA variant leads to EDA-ID R-HSA-5603029
TNFR1-induced NFkappaB signaling pathway R-HSA-5357956
MAP kinase activation R-HSA-450294
Regulation of TNFR1 signaling R-HSA-5357905
C-type lectin receptors (CLRs) R-HSA-5621481
FCERI mediated NF-kB activation R-HSA-2871837
Innate Immune System R-HSA-168249
p75 NTR receptor-mediated signalling R-HSA-193704
CLEC7A (Dectin-1) signaling R-HSA-5607764
Immune System R-HSA-168256
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027
p75NTR signals via NF-kB R-HSA-193639
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
SARS-CoV-2-host interactions R-HSA-9705683
Downstream TCR signaling R-HSA-202424
MyD88 cascade initiated on plasma membrane R-HSA-975871
Interleukin-17 signaling R-HSA-448424
Class I MHC mediated antigen processing & presentation R-HSA-983169
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Diseases associated with the TLR signaling cascade R-HSA-5602358
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
NF-kB is activated and signals survival R-HSA-209560
Signal Transduction R-HSA-162582
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
IRAK1 recruits IKK complex R-HSA-937039
SARS-CoV Infections R-HSA-9679506
Toll-like Receptor Cascades R-HSA-168898
Signaling by Interleukins R-HSA-449147
Infectious disease R-HSA-5663205
SARS-CoV-2 Infection R-HSA-9694516
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Interleukin-1 signaling R-HSA-9020702
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cytokine Signaling in Immune system R-HSA-1280215
Antigen processing-Cross presentation R-HSA-1236975
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88-independent TLR4 cascade R-HSA-166166
IKBKB deficiency causes SCID R-HSA-5602636
NOD1/2 Signaling Pathway R-HSA-168638
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Diseases of Immune System R-HSA-5260271
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 dependent cascade initiated on endosome R-HSA-975155
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Disease R-HSA-1643685
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927
ER-Phagosome pathway R-HSA-1236974
IKK complex recruitment mediated by RIP1 R-HSA-937041
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
TCR signaling R-HSA-202403
p75NTR recruits signalling complexes R-HSA-209543
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TNF signaling R-HSA-75893

Expression Atlas ENSG00000104365
LRG display in Ensembl gene LRG_1241
NCBI gene (formerly Entrezgene) 3551
GeneCards 5960
HGNC Symbol HGNC:5960
MIM gene 603258
MIM morbid 618204
UniProtKB Gene Name O14920
WikiGene 3551
Gene: FLT1
Ensembl ID : ENSG00000102755
Description: fms related receptor tyrosine kinase 1
Gene Synonyms: FLT,VEGFR1
45 APIs:
199 Possible Orthologues:

Signaling by VEGF R-HSA-194138
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signaling by VEGF R-HSA-194138
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signal Transduction R-HSA-162582
VEGF ligand-receptor interactions R-HSA-194313
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
VEGF ligand-receptor interactions R-HSA-194313
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF ligand-receptor interactions R-HSA-194313
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signal Transduction R-HSA-162582
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
VEGF ligand-receptor interactions R-HSA-194313
Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signal Transduction R-HSA-162582
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signaling by VEGF R-HSA-194138

Expression Atlas ENSG00000102755
LRG display in Ensembl gene LRG_425
NCBI gene (formerly Entrezgene) 2321
GeneCards 3763
HGNC Symbol HGNC:3763
MIM gene 165070
UniProtKB Gene Name P17948
WikiGene 2321
Gene: NTRK1
Ensembl ID : ENSG00000198400
Description: neurotrophic receptor tyrosine kinase 1
Gene Synonyms: MTC,TRK,TRKA
6 APIs:
200 Possible Orthologues:

Signalling to p38 via RIT and RIN R-HSA-187706
Signalling to ERKs R-HSA-187687
Prolonged ERK activation events R-HSA-169893
Signalling to STAT3 R-HSA-198745
Signalling to p38 via RIT and RIN R-HSA-187706
PLC-gamma1 signalling R-HSA-167021
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Frs2-mediated activation R-HSA-170968
ARMS-mediated activation R-HSA-170984
NGF-independant TRKA activation R-HSA-187024
Signaling by NTRK1 (TRKA) R-HSA-187037
Activation of TRKA receptors R-HSA-187015
TRKA activation by NGF R-HSA-187042
PI3K/AKT activation R-HSA-198203
Signaling by NTRKs R-HSA-166520
Signal Transduction R-HSA-162582
Signalling to RAS R-HSA-167044
Retrograde neurotrophin signalling R-HSA-177504
Activation of TRKA receptors R-HSA-187015
Signaling by NTRK1 (TRKA) R-HSA-187037
Retrograde neurotrophin signalling R-HSA-177504
PLC-gamma1 signalling R-HSA-167021
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NGF-independant TRKA activation R-HSA-187024
Signal Transduction R-HSA-162582
Signaling by NTRKs R-HSA-166520
Signalling to p38 via RIT and RIN R-HSA-187706
PI3K/AKT activation R-HSA-198203
TRKA activation by NGF R-HSA-187042
Prolonged ERK activation events R-HSA-169893
ARMS-mediated activation R-HSA-170984
Signalling to STAT3 R-HSA-198745
Signalling to ERKs R-HSA-187687
Signalling to RAS R-HSA-167044
Frs2-mediated activation R-HSA-170968
Signalling to ERKs R-HSA-187687
Prolonged ERK activation events R-HSA-169893
ARMS-mediated activation R-HSA-170984
Frs2-mediated activation R-HSA-170968
Activation of TRKA receptors R-HSA-187015
PLC-gamma1 signalling R-HSA-167021
Signalling to STAT3 R-HSA-198745
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K/AKT activation R-HSA-198203
Signal Transduction R-HSA-162582
TRKA activation by NGF R-HSA-187042
Signaling by NTRKs R-HSA-166520
NGF-independant TRKA activation R-HSA-187024
Signalling to RAS R-HSA-167044
Signalling to p38 via RIT and RIN R-HSA-187706
Retrograde neurotrophin signalling R-HSA-177504
PLC-gamma1 signalling R-HSA-167021
Signaling by NTRK1 (TRKA) R-HSA-187037
Signal Transduction R-HSA-162582
NGF-independant TRKA activation R-HSA-187024
Frs2-mediated activation R-HSA-170968
Signalling to STAT3 R-HSA-198745
Retrograde neurotrophin signalling R-HSA-177504
Activation of TRKA receptors R-HSA-187015
Signalling to p38 via RIT and RIN R-HSA-187706
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
TRKA activation by NGF R-HSA-187042
PI3K/AKT activation R-HSA-198203
Signaling by NTRKs R-HSA-166520
Signalling to ERKs R-HSA-187687
ARMS-mediated activation R-HSA-170984
Signalling to RAS R-HSA-167044
Prolonged ERK activation events R-HSA-169893
Retrograde neurotrophin signalling R-HSA-177504
PLC-gamma1 signalling R-HSA-167021
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRKs R-HSA-166520
Signalling to ERKs R-HSA-187687
Signal Transduction R-HSA-162582
Activation of TRKA receptors R-HSA-187015
ARMS-mediated activation R-HSA-170984
Signaling by NTRK1 (TRKA) R-HSA-187037
TRKA activation by NGF R-HSA-187042
Signalling to STAT3 R-HSA-198745
Signalling to p38 via RIT and RIN R-HSA-187706
PI3K/AKT activation R-HSA-198203
NGF-independant TRKA activation R-HSA-187024
Frs2-mediated activation R-HSA-170968
Signalling to RAS R-HSA-167044
Prolonged ERK activation events R-HSA-169893
Signalling to STAT3 R-HSA-198745
Signalling to ERKs R-HSA-187687
TRKA activation by NGF R-HSA-187042
Signaling by NTRKs R-HSA-166520
Signal Transduction R-HSA-162582
PI3K/AKT activation R-HSA-198203
Signalling to p38 via RIT and RIN R-HSA-187706
Signalling to RAS R-HSA-167044
Frs2-mediated activation R-HSA-170968
Prolonged ERK activation events R-HSA-169893
Activation of TRKA receptors R-HSA-187015
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
ARMS-mediated activation R-HSA-170984
Retrograde neurotrophin signalling R-HSA-177504
PLC-gamma1 signalling R-HSA-167021
NGF-independant TRKA activation R-HSA-187024
Signalling to STAT3 R-HSA-198745
NGF-independant TRKA activation R-HSA-187024
Signaling by NTRK1 (TRKA) R-HSA-187037
Signal Transduction R-HSA-162582
Activation of TRKA receptors R-HSA-187015
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signalling to ERKs R-HSA-187687
Signaling by NTRKs R-HSA-166520
Signalling to RAS R-HSA-167044
Retrograde neurotrophin signalling R-HSA-177504
Prolonged ERK activation events R-HSA-169893
Frs2-mediated activation R-HSA-170968
PI3K/AKT activation R-HSA-198203
PLC-gamma1 signalling R-HSA-167021
ARMS-mediated activation R-HSA-170984
Signalling to p38 via RIT and RIN R-HSA-187706
TRKA activation by NGF R-HSA-187042
Signalling to RAS R-HSA-167044
Signalling to STAT3 R-HSA-198745
PLC-gamma1 signalling R-HSA-167021
Signalling to ERKs R-HSA-187687
PI3K/AKT activation R-HSA-198203
Retrograde neurotrophin signalling R-HSA-177504
Signaling by NTRK1 (TRKA) R-HSA-187037
TRKA activation by NGF R-HSA-187042
Frs2-mediated activation R-HSA-170968
Prolonged ERK activation events R-HSA-169893
ARMS-mediated activation R-HSA-170984
Signaling by NTRKs R-HSA-166520
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
NGF-independant TRKA activation R-HSA-187024
Activation of TRKA receptors R-HSA-187015
Signal Transduction R-HSA-162582
TRKA activation by NGF R-HSA-187042
Activation of TRKA receptors R-HSA-187015
ARMS-mediated activation R-HSA-170984
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Prolonged ERK activation events R-HSA-169893
Signalling to ERKs R-HSA-187687
PLC-gamma1 signalling R-HSA-167021
Signaling by NTRK1 (TRKA) R-HSA-187037
Signalling to p38 via RIT and RIN R-HSA-187706
Retrograde neurotrophin signalling R-HSA-177504
Signaling by NTRKs R-HSA-166520
NGF-independant TRKA activation R-HSA-187024
Signalling to RAS R-HSA-167044
Frs2-mediated activation R-HSA-170968
Signalling to STAT3 R-HSA-198745
PI3K/AKT activation R-HSA-198203
Signalling to STAT3 R-HSA-198745
Signalling to ERKs R-HSA-187687
Frs2-mediated activation R-HSA-170968
Prolonged ERK activation events R-HSA-169893
Signaling by NTRKs R-HSA-166520
PI3K/AKT activation R-HSA-198203
NGF-independant TRKA activation R-HSA-187024
ARMS-mediated activation R-HSA-170984
Signalling to p38 via RIT and RIN R-HSA-187706
Signaling by NTRK1 (TRKA) R-HSA-187037
TRKA activation by NGF R-HSA-187042
Activation of TRKA receptors R-HSA-187015
Retrograde neurotrophin signalling R-HSA-177504
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PLC-gamma1 signalling R-HSA-167021
Signalling to RAS R-HSA-167044

Expression Atlas ENSG00000198400
LRG display in Ensembl gene LRG_261
NCBI gene (formerly Entrezgene) 4914
GeneCards 8031
HGNC Symbol HGNC:8031
MIM gene 191315
MIM morbid 256800
UniProtKB Gene Name X5DR71
WikiGene 4914
Gene: EML4
Ensembl ID : ENSG00000143924
Description: EMAP like 4
Gene Synonyms: C2ORF2,ELP120,ROPP120
5 APIs:
214 Possible Orthologues:

ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK in cancer R-HSA-9700206
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Mitotic Prometaphase R-HSA-68877
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
ALK mutants bind TKIs R-HSA-9700645
Disease R-HSA-1643685
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK fusions and activated point mutants R-HSA-9725370
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Cell Cycle R-HSA-1640170
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
M Phase R-HSA-68886
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Cell Cycle, Mitotic R-HSA-69278
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Mitotic Prometaphase R-HSA-68877
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
ALK mutants bind TKIs R-HSA-9700645
M Phase R-HSA-68886
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK in cancer R-HSA-9700206
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
ALK mutants bind TKIs R-HSA-9700645
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Cell Cycle, Mitotic R-HSA-69278
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Signaling by ALK in cancer R-HSA-9700206
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
ALK mutants bind TKIs R-HSA-9700645
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Mitotic Prometaphase R-HSA-68877
Cell Cycle, Mitotic R-HSA-69278
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
Disease R-HSA-1643685
ALK mutants bind TKIs R-HSA-9700645
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by ALK in cancer R-HSA-9700206
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell Cycle, Mitotic R-HSA-69278
Signaling by ALK in cancer R-HSA-9700206
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Disease R-HSA-1643685
Mitotic Prometaphase R-HSA-68877
ALK mutants bind TKIs R-HSA-9700645
Cell Cycle R-HSA-1640170
EML4 and NUDC in mitotic spindle formation R-HSA-9648025
M Phase R-HSA-68886

Expression Atlas ENSG00000143924
NCBI gene (formerly Entrezgene) 27436
GeneCards 1316
HGNC Symbol HGNC:1316
MIM gene 607442
UniProtKB Gene Name Q9HC35
WikiGene 27436
Gene: PIK3CB
Ensembl ID : ENSG00000051382
Description: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
Gene Synonyms: PIK3C1
31 APIs:
216 Possible Orthologues:

Axon guidance R-HSA-422475
IRS-mediated signalling R-HSA-112399
DAP12 interactions R-HSA-2172127
Role of phospholipids in phagocytosis R-HSA-2029485
Regulation of signaling by CBL R-HSA-912631
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
GPVI-mediated activation cascade R-HSA-114604
PI3K/AKT Signaling in Cancer R-HSA-2219528
Tie2 Signaling R-HSA-210993
Nephrin family interactions R-HSA-373753
Downstream TCR signaling R-HSA-202424
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin receptor SHC signaling R-HSA-912526
Insulin receptor signalling cascade R-HSA-74751
RET signaling R-HSA-8853659
Developmental Biology R-HSA-1266738
MAPK1/MAPK3 signaling R-HSA-5684996
TCR signaling R-HSA-202403
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Metabolism of lipids R-HSA-556833
Signaling by PDGFR in disease R-HSA-9671555
Intracellular signaling by second messengers R-HSA-9006925
IRS-mediated signalling R-HSA-112399
Adaptive Immune System R-HSA-1280218
Hemostasis R-HSA-109582
PI3K/AKT activation R-HSA-198203
IGF1R signaling cascade R-HSA-2428924
Signaling by NTRK1 (TRKA) R-HSA-187037
DAP12 interactions R-HSA-2172127
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
Disease R-HSA-1643685
Signaling by VEGF R-HSA-194138
Signaling by Erythropoietin R-HSA-9006335
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by ALK R-HSA-201556
MAPK family signaling cascades R-HSA-5683057
Signaling by PDGF R-HSA-186797
DAP12 signaling R-HSA-2424491
RAF/MAP kinase cascade R-HSA-5673001
Downstream signal transduction R-HSA-186763
Metabolism R-HSA-1430728
Interleukin-2 family signaling R-HSA-451927
Signaling by Interleukins R-HSA-449147
Phospholipid metabolism R-HSA-1483257
Cell surface interactions at the vascular wall R-HSA-202733
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Platelet activation, signaling and aggregation R-HSA-76002
Cytokine Signaling in Immune system R-HSA-1280215
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI Metabolism R-HSA-1483255
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
PI3K Cascade R-HSA-109704
Nervous system development R-HSA-9675108
Signaling by NTRKs R-HSA-166520
Signaling by Insulin receptor R-HSA-74752
Immune System R-HSA-168256
Cell-Cell communication R-HSA-1500931
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Axon guidance R-HSA-422475
Downstream signal transduction R-HSA-186763
Cell-Cell communication R-HSA-1500931
Innate Immune System R-HSA-168249
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
MAPK family signaling cascades R-HSA-5683057
Immune System R-HSA-168256
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
TCR signaling R-HSA-202403
Metabolism R-HSA-1430728
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Adaptive Immune System R-HSA-1280218
Interleukin-2 family signaling R-HSA-451927
Cytokine Signaling in Immune system R-HSA-1280215
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Regulation of signaling by CBL R-HSA-912631
Signaling by PDGFR in disease R-HSA-9671555
Phospholipid metabolism R-HSA-1483257
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Intracellular signaling by second messengers R-HSA-9006925
RET signaling R-HSA-8853659
Hemostasis R-HSA-109582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Insulin receptor signalling cascade R-HSA-74751
Signal Transduction R-HSA-162582
Metabolism of lipids R-HSA-556833
Role of phospholipids in phagocytosis R-HSA-2029485
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
VEGFA-VEGFR2 Pathway R-HSA-4420097
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K Cascade R-HSA-109704
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Insulin receptor R-HSA-74752
Signaling by Erythropoietin R-HSA-9006335
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Negative regulation of the PI3K/AKT network R-HSA-199418
IRS-related events triggered by IGF1R R-HSA-2428928
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by NTRK1 (TRKA) R-HSA-187037
Cell surface interactions at the vascular wall R-HSA-202733
IRS-mediated signalling R-HSA-112399
Platelet activation, signaling and aggregation R-HSA-76002
Interleukin receptor SHC signaling R-HSA-912526
DAP12 interactions R-HSA-2172127
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nephrin family interactions R-HSA-373753
DAP12 signaling R-HSA-2424491
Signaling by ALK R-HSA-201556
Tie2 Signaling R-HSA-210993
PI3K/AKT activation R-HSA-198203
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
Signaling by VEGF R-HSA-194138
IGF1R signaling cascade R-HSA-2428924
Downstream TCR signaling R-HSA-202424
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Nervous system development R-HSA-9675108
RAF/MAP kinase cascade R-HSA-5673001
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
PI Metabolism R-HSA-1483255
Signaling by PDGF R-HSA-186797
PIP3 activates AKT signaling R-HSA-1257604
Signaling by NTRKs R-HSA-166520
Disease R-HSA-1643685
GPVI-mediated activation cascade R-HSA-114604
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
IRS-mediated signalling R-HSA-112399
Signaling by PDGF R-HSA-186797
Regulation of signaling by CBL R-HSA-912631
Signaling by VEGF R-HSA-194138
Cell-Cell communication R-HSA-1500931
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Adaptive Immune System R-HSA-1280218
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
DAP12 signaling R-HSA-2424491
Role of phospholipids in phagocytosis R-HSA-2029485
Tie2 Signaling R-HSA-210993
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Negative regulation of the PI3K/AKT network R-HSA-199418
Intracellular signaling by second messengers R-HSA-9006925
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IGF1R signaling cascade R-HSA-2428924
Metabolism R-HSA-1430728
Signaling by Erythropoietin R-HSA-9006335
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
TCR signaling R-HSA-202403
Nephrin family interactions R-HSA-373753
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by NTRKs R-HSA-166520
PI Metabolism R-HSA-1483255
Interleukin receptor SHC signaling R-HSA-912526
Phospholipid metabolism R-HSA-1483257
Immune System R-HSA-168256
Insulin receptor signalling cascade R-HSA-74751
Axon guidance R-HSA-422475
Signaling by PDGFR in disease R-HSA-9671555
Signaling by Interleukins R-HSA-449147
MAPK family signaling cascades R-HSA-5683057
PIP3 activates AKT signaling R-HSA-1257604
Downstream TCR signaling R-HSA-202424
PI3K Cascade R-HSA-109704
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
PI3K/AKT activation R-HSA-198203
Hemostasis R-HSA-109582
Metabolism of lipids R-HSA-556833
Innate Immune System R-HSA-168249
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
RAF/MAP kinase cascade R-HSA-5673001
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nervous system development R-HSA-9675108
Downstream signal transduction R-HSA-186763
Cell surface interactions at the vascular wall R-HSA-202733
Disease R-HSA-1643685
GPVI-mediated activation cascade R-HSA-114604
DAP12 interactions R-HSA-2172127
Signaling by Insulin receptor R-HSA-74752
Cytokine Signaling in Immune system R-HSA-1280215
Developmental Biology R-HSA-1266738
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Interleukin-2 family signaling R-HSA-451927
MAPK1/MAPK3 signaling R-HSA-5684996
RET signaling R-HSA-8853659
Signaling by NTRK1 (TRKA) R-HSA-187037
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by ALK R-HSA-201556
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ALK R-HSA-201556
Signaling by Interleukins R-HSA-449147
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PIP3 activates AKT signaling R-HSA-1257604
Role of phospholipids in phagocytosis R-HSA-2029485
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by VEGF R-HSA-194138
Adaptive Immune System R-HSA-1280218
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by PDGF R-HSA-186797
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Cell surface interactions at the vascular wall R-HSA-202733
Innate Immune System R-HSA-168249
IGF1R signaling cascade R-HSA-2428924
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGFR in disease R-HSA-9671555
RAF/MAP kinase cascade R-HSA-5673001
PI3K Cascade R-HSA-109704
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
PI3K/AKT Signaling in Cancer R-HSA-2219528
Disease R-HSA-1643685
Synthesis of PIPs at the plasma membrane R-HSA-1660499
IRS-mediated signalling R-HSA-112399
IRS-related events triggered by IGF1R R-HSA-2428928
Downstream TCR signaling R-HSA-202424
Intracellular signaling by second messengers R-HSA-9006925
Phospholipid metabolism R-HSA-1483257
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by NTRK1 (TRKA) R-HSA-187037
Negative regulation of the PI3K/AKT network R-HSA-199418
Hemostasis R-HSA-109582
Interleukin-2 family signaling R-HSA-451927
Signaling by NTRKs R-HSA-166520
VEGFA-VEGFR2 Pathway R-HSA-4420097
Downstream signal transduction R-HSA-186763
DAP12 interactions R-HSA-2172127
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
Interleukin receptor SHC signaling R-HSA-912526
RET signaling R-HSA-8853659
PI3K/AKT activation R-HSA-198203
GPVI-mediated activation cascade R-HSA-114604
Immune System R-HSA-168256
TCR signaling R-HSA-202403
Regulation of signaling by CBL R-HSA-912631
DAP12 signaling R-HSA-2424491
MAPK family signaling cascades R-HSA-5683057
PI Metabolism R-HSA-1483255
Signaling by Insulin receptor R-HSA-74752
Insulin receptor signalling cascade R-HSA-74751
Nephrin family interactions R-HSA-373753
Tie2 Signaling R-HSA-210993
Platelet activation, signaling and aggregation R-HSA-76002
Cytokine Signaling in Immune system R-HSA-1280215
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by Erythropoietin R-HSA-9006335
Cell-Cell communication R-HSA-1500931
MAPK1/MAPK3 signaling R-HSA-5684996
Cell surface interactions at the vascular wall R-HSA-202733
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PI Metabolism R-HSA-1483255
GPVI-mediated activation cascade R-HSA-114604
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
IRS-mediated signalling R-HSA-112399
Signaling by Interleukins R-HSA-449147
Signaling by NTRK1 (TRKA) R-HSA-187037
Downstream TCR signaling R-HSA-202424
DAP12 signaling R-HSA-2424491
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Regulation of signaling by CBL R-HSA-912631
Role of phospholipids in phagocytosis R-HSA-2029485
Disease R-HSA-1643685
Immune System R-HSA-168256
MAPK1/MAPK3 signaling R-HSA-5684996
IRS-related events triggered by IGF1R R-HSA-2428928
Interleukin-2 family signaling R-HSA-451927
Signaling by ALK R-HSA-201556
PI3K/AKT activation R-HSA-198203
RAF/MAP kinase cascade R-HSA-5673001
Innate Immune System R-HSA-168249
Cytokine Signaling in Immune system R-HSA-1280215
IGF1R signaling cascade R-HSA-2428924
DAP12 interactions R-HSA-2172127
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by PDGF R-HSA-186797
Phospholipid metabolism R-HSA-1483257
Nephrin family interactions R-HSA-373753
Downstream signal transduction R-HSA-186763
Interleukin receptor SHC signaling R-HSA-912526
Signal Transduction R-HSA-162582
Insulin receptor signalling cascade R-HSA-74751
Adaptive Immune System R-HSA-1280218
PIP3 activates AKT signaling R-HSA-1257604
VEGFA-VEGFR2 Pathway R-HSA-4420097
MAPK family signaling cascades R-HSA-5683057
Signaling by Erythropoietin R-HSA-9006335
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Platelet activation, signaling and aggregation R-HSA-76002
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Cell-Cell communication R-HSA-1500931
Nervous system development R-HSA-9675108
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Metabolism R-HSA-1430728
PI3K/AKT Signaling in Cancer R-HSA-2219528
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Tie2 Signaling R-HSA-210993
TCR signaling R-HSA-202403
PI3K Cascade R-HSA-109704
Developmental Biology R-HSA-1266738
Negative regulation of the PI3K/AKT network R-HSA-199418
RET signaling R-HSA-8853659
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by PDGFR in disease R-HSA-9671555
Signaling by NTRKs R-HSA-166520
Signaling by Insulin receptor R-HSA-74752
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Intracellular signaling by second messengers R-HSA-9006925
Hemostasis R-HSA-109582
Axon guidance R-HSA-422475
Signaling by VEGF R-HSA-194138
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Metabolism of lipids R-HSA-556833
Platelet activation, signaling and aggregation R-HSA-76002
Downstream TCR signaling R-HSA-202424
DAP12 signaling R-HSA-2424491
TCR signaling R-HSA-202403
PI3K/AKT Signaling in Cancer R-HSA-2219528
VEGFA-VEGFR2 Pathway R-HSA-4420097
PI3K Cascade R-HSA-109704
IRS-mediated signalling R-HSA-112399
Signaling by PDGF R-HSA-186797
Metabolism of lipids R-HSA-556833
Downstream signal transduction R-HSA-186763
Signaling by Interleukins R-HSA-449147
Adaptive Immune System R-HSA-1280218
Signaling by Insulin receptor R-HSA-74752
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by VEGF R-HSA-194138
Intracellular signaling by second messengers R-HSA-9006925
IGF1R signaling cascade R-HSA-2428924
MAPK family signaling cascades R-HSA-5683057
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by NTRK1 (TRKA) R-HSA-187037
Interleukin-2 family signaling R-HSA-451927
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
IRS-related events triggered by IGF1R R-HSA-2428928
GPVI-mediated activation cascade R-HSA-114604
RAF/MAP kinase cascade R-HSA-5673001
Signaling by ALK R-HSA-201556
Insulin receptor signalling cascade R-HSA-74751
Signaling by PDGFR in disease R-HSA-9671555
PIP3 activates AKT signaling R-HSA-1257604
Interleukin receptor SHC signaling R-HSA-912526
Developmental Biology R-HSA-1266738
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
DAP12 interactions R-HSA-2172127
Immune System R-HSA-168256
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by Erythropoietin R-HSA-9006335
Cell surface interactions at the vascular wall R-HSA-202733
PI Metabolism R-HSA-1483255
Phospholipid metabolism R-HSA-1483257
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Hemostasis R-HSA-109582
Role of phospholipids in phagocytosis R-HSA-2029485
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Metabolism R-HSA-1430728
PI3K/AKT activation R-HSA-198203
Signal Transduction R-HSA-162582
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Axon guidance R-HSA-422475
Nephrin family interactions R-HSA-373753
Cell-Cell communication R-HSA-1500931
Innate Immune System R-HSA-168249
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RET signaling R-HSA-8853659
Signaling by NTRKs R-HSA-166520
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Tie2 Signaling R-HSA-210993
Regulation of signaling by CBL R-HSA-912631
MAPK1/MAPK3 signaling R-HSA-5684996
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Downstream TCR signaling R-HSA-202424
Role of phospholipids in phagocytosis R-HSA-2029485
Nephrin family interactions R-HSA-373753
Signaling by Erythropoietin R-HSA-9006335
Cytokine Signaling in Immune system R-HSA-1280215
VEGFA-VEGFR2 Pathway R-HSA-4420097
Intracellular signaling by second messengers R-HSA-9006925
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell-Cell communication R-HSA-1500931
Regulation of signaling by CBL R-HSA-912631
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
PI3K/AKT activation R-HSA-198203
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by PDGF R-HSA-186797
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RET signaling R-HSA-8853659
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Phospholipid metabolism R-HSA-1483257
Cell surface interactions at the vascular wall R-HSA-202733
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Insulin receptor R-HSA-74752
Nervous system development R-HSA-9675108
IRS-mediated signalling R-HSA-112399
Signaling by NTRKs R-HSA-166520
Downstream signal transduction R-HSA-186763
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Interleukin-2 family signaling R-HSA-451927
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI Metabolism R-HSA-1483255
IGF1R signaling cascade R-HSA-2428924
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
Interleukin receptor SHC signaling R-HSA-912526
Insulin receptor signalling cascade R-HSA-74751
Signaling by ALK R-HSA-201556
PI3K Cascade R-HSA-109704
RAF/MAP kinase cascade R-HSA-5673001
Hemostasis R-HSA-109582
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by PDGFR in disease R-HSA-9671555
Immune System R-HSA-168256
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Metabolism of lipids R-HSA-556833
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
PIP3 activates AKT signaling R-HSA-1257604
Metabolism R-HSA-1430728
DAP12 signaling R-HSA-2424491
Platelet activation, signaling and aggregation R-HSA-76002
MAPK1/MAPK3 signaling R-HSA-5684996
Tie2 Signaling R-HSA-210993
Signaling by VEGF R-HSA-194138
GPVI-mediated activation cascade R-HSA-114604
Disease R-HSA-1643685
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Negative regulation of the PI3K/AKT network R-HSA-199418
Adaptive Immune System R-HSA-1280218
DAP12 interactions R-HSA-2172127
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by NTRK1 (TRKA) R-HSA-187037
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT activation R-HSA-198203
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
RET signaling R-HSA-8853659
Signaling by PDGF R-HSA-186797
Disease R-HSA-1643685
Cell surface interactions at the vascular wall R-HSA-202733
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Erythropoietin R-HSA-9006335
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Innate Immune System R-HSA-168249
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
IRS-related events triggered by IGF1R R-HSA-2428928
Regulation of signaling by CBL R-HSA-912631
Axon guidance R-HSA-422475
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Phospholipid metabolism R-HSA-1483257
Nervous system development R-HSA-9675108
TCR signaling R-HSA-202403
DAP12 signaling R-HSA-2424491
Signaling by NTRKs R-HSA-166520
Signaling by Interleukins R-HSA-449147
Signaling by NTRK1 (TRKA) R-HSA-187037
Downstream signal transduction R-HSA-186763
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
PI Metabolism R-HSA-1483255
Hemostasis R-HSA-109582
IGF1R signaling cascade R-HSA-2428924
Cytokine Signaling in Immune system R-HSA-1280215
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism R-HSA-1430728
IRS-mediated signalling R-HSA-112399
PIP3 activates AKT signaling R-HSA-1257604
Insulin receptor signalling cascade R-HSA-74751
PI3K Cascade R-HSA-109704
Immune System R-HSA-168256
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
Intracellular signaling by second messengers R-HSA-9006925
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
VEGFA-VEGFR2 Pathway R-HSA-4420097
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Insulin receptor R-HSA-74752
Nephrin family interactions R-HSA-373753
Metabolism of lipids R-HSA-556833
Signaling by PDGFR in disease R-HSA-9671555
Cell-Cell communication R-HSA-1500931
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Interleukin-2 family signaling R-HSA-451927
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Interleukin receptor SHC signaling R-HSA-912526
Adaptive Immune System R-HSA-1280218
Tie2 Signaling R-HSA-210993
DAP12 interactions R-HSA-2172127
GPVI-mediated activation cascade R-HSA-114604
Downstream TCR signaling R-HSA-202424
Signaling by VEGF R-HSA-194138
Signaling by ALK R-HSA-201556
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PI3K/AKT Signaling in Cancer R-HSA-2219528
Role of phospholipids in phagocytosis R-HSA-2029485
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
IGF1R signaling cascade R-HSA-2428924
PI3K Cascade R-HSA-109704
RET signaling R-HSA-8853659
Metabolism R-HSA-1430728
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Interleukin receptor SHC signaling R-HSA-912526
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by VEGF R-HSA-194138
TCR signaling R-HSA-202403
Downstream signal transduction R-HSA-186763
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Nervous system development R-HSA-9675108
GPVI-mediated activation cascade R-HSA-114604
Tie2 Signaling R-HSA-210993
Developmental Biology R-HSA-1266738
Signaling by PDGF R-HSA-186797
Signaling by NTRK1 (TRKA) R-HSA-187037
RAF/MAP kinase cascade R-HSA-5673001
Intracellular signaling by second messengers R-HSA-9006925
Adaptive Immune System R-HSA-1280218
Axon guidance R-HSA-422475
DAP12 signaling R-HSA-2424491
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by ALK R-HSA-201556
Metabolism of lipids R-HSA-556833
Signaling by Interleukins R-HSA-449147
Role of phospholipids in phagocytosis R-HSA-2029485
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Insulin receptor signalling cascade R-HSA-74751
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Cell-Cell communication R-HSA-1500931
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Nephrin family interactions R-HSA-373753
IRS-related events triggered by IGF1R R-HSA-2428928
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Disease R-HSA-1643685
Immune System R-HSA-168256
Downstream TCR signaling R-HSA-202424
Signaling by PDGFR in disease R-HSA-9671555
Interleukin-2 family signaling R-HSA-451927
Signaling by Insulin receptor R-HSA-74752
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Erythropoietin R-HSA-9006335
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI3K/AKT activation R-HSA-198203
Innate Immune System R-HSA-168249
PI Metabolism R-HSA-1483255
MAPK family signaling cascades R-HSA-5683057
Phospholipid metabolism R-HSA-1483257
Regulation of signaling by CBL R-HSA-912631
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by NTRKs R-HSA-166520
Hemostasis R-HSA-109582
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PI3K/AKT Signaling in Cancer R-HSA-2219528
Negative regulation of the PI3K/AKT network R-HSA-199418
MAPK1/MAPK3 signaling R-HSA-5684996
PIP3 activates AKT signaling R-HSA-1257604
TCR signaling R-HSA-202403
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Negative regulation of the PI3K/AKT network R-HSA-199418
PIP3 activates AKT signaling R-HSA-1257604
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Downstream signal transduction R-HSA-186763
Phospholipid metabolism R-HSA-1483257
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Innate Immune System R-HSA-168249
Platelet activation, signaling and aggregation R-HSA-76002
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RAF/MAP kinase cascade R-HSA-5673001
GPVI-mediated activation cascade R-HSA-114604
Metabolism of lipids R-HSA-556833
Signaling by Interleukins R-HSA-449147
PI Metabolism R-HSA-1483255
Hemostasis R-HSA-109582
Interleukin receptor SHC signaling R-HSA-912526
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IGF1R signaling cascade R-HSA-2428924
Signaling by Insulin receptor R-HSA-74752
IRS-related events triggered by IGF1R R-HSA-2428928
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by PDGF R-HSA-186797
Disease R-HSA-1643685
IRS-mediated signalling R-HSA-112399
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by NTRKs R-HSA-166520
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Intracellular signaling by second messengers R-HSA-9006925
DAP12 signaling R-HSA-2424491
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Cell-Cell communication R-HSA-1500931
PI3K/AKT activation R-HSA-198203
Interleukin-2 family signaling R-HSA-451927
Developmental Biology R-HSA-1266738
Adaptive Immune System R-HSA-1280218
Downstream TCR signaling R-HSA-202424
Signaling by PDGFR in disease R-HSA-9671555
Nephrin family interactions R-HSA-373753
Insulin receptor signalling cascade R-HSA-74751
Metabolism R-HSA-1430728
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signal Transduction R-HSA-162582
Tie2 Signaling R-HSA-210993
Regulation of signaling by CBL R-HSA-912631
Signaling by Erythropoietin R-HSA-9006335
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by ALK R-HSA-201556
VEGFA-VEGFR2 Pathway R-HSA-4420097
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Role of phospholipids in phagocytosis R-HSA-2029485
Cell surface interactions at the vascular wall R-HSA-202733
DAP12 interactions R-HSA-2172127
PI3K Cascade R-HSA-109704
Signaling by VEGF R-HSA-194138
Immune System R-HSA-168256
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
MAPK family signaling cascades R-HSA-5683057
RET signaling R-HSA-8853659
MAPK1/MAPK3 signaling R-HSA-5684996
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202

Expression Atlas ENSG00000051382
NCBI gene (formerly Entrezgene) 5291
GeneCards 8976
HGNC Symbol HGNC:8976
MIM gene 602925
UniProtKB Gene Name Q68DL0
WikiGene 5291
Gene: PRKDC
Ensembl ID : ENSG00000253729
Description: protein kinase, DNA-activated, catalytic subunit
Gene Synonyms: DNA-PKC,DNA-PKCS,DNAPK,DNAPKC,DNPK1,HYRC,HYRC1,P350,P460,XRCC7
1 APIs:
187 Possible Orthologues:

Immune System R-HSA-168256
Protein ubiquitination R-HSA-8852135
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
DNA Repair R-HSA-73894
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
IRF3-mediated induction of type I IFN R-HSA-3270619
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
DNA Double-Strand Break Repair R-HSA-5693532
Metabolism of proteins R-HSA-392499
STING mediated induction of host immune responses R-HSA-1834941
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
STING mediated induction of host immune responses R-HSA-1834941
Protein ubiquitination R-HSA-8852135
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
IRF3-mediated induction of type I IFN R-HSA-3270619
Metabolism of proteins R-HSA-392499
DNA Double-Strand Break Repair R-HSA-5693532
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Post-translational protein modification R-HSA-597592
DNA Repair R-HSA-73894
IRF3-mediated induction of type I IFN R-HSA-3270619
Protein ubiquitination R-HSA-8852135
DNA Double-Strand Break Repair R-HSA-5693532
DNA Repair R-HSA-73894
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Immune System R-HSA-168256
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
STING mediated induction of host immune responses R-HSA-1834941
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
IRF3-mediated induction of type I IFN R-HSA-3270619
STING mediated induction of host immune responses R-HSA-1834941
DNA Repair R-HSA-73894
Immune System R-HSA-168256
DNA Double-Strand Break Repair R-HSA-5693532
Innate Immune System R-HSA-168249
Post-translational protein modification R-HSA-597592
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Protein ubiquitination R-HSA-8852135
Metabolism of proteins R-HSA-392499
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
DNA Repair R-HSA-73894
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
IRF3-mediated induction of type I IFN R-HSA-3270619
Immune System R-HSA-168256
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
DNA Double-Strand Break Repair R-HSA-5693532
Innate Immune System R-HSA-168249
Protein ubiquitination R-HSA-8852135
Metabolism of proteins R-HSA-392499
STING mediated induction of host immune responses R-HSA-1834941
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
Post-translational protein modification R-HSA-597592
Post-translational protein modification R-HSA-597592
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
STING mediated induction of host immune responses R-HSA-1834941
IRF3-mediated induction of type I IFN R-HSA-3270619
Protein ubiquitination R-HSA-8852135
DNA Repair R-HSA-73894
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Innate Immune System R-HSA-168249
DNA Double-Strand Break Repair R-HSA-5693532
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
STING mediated induction of host immune responses R-HSA-1834941
DNA Double-Strand Break Repair R-HSA-5693532
IRF3-mediated induction of type I IFN R-HSA-3270619
Immune System R-HSA-168256
DNA Repair R-HSA-73894
Innate Immune System R-HSA-168249
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
Post-translational protein modification R-HSA-597592
Protein ubiquitination R-HSA-8852135
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
IRF3-mediated induction of type I IFN R-HSA-3270619
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
DNA Repair R-HSA-73894
DNA Double-Strand Break Repair R-HSA-5693532
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
STING mediated induction of host immune responses R-HSA-1834941
Protein ubiquitination R-HSA-8852135
Post-translational protein modification R-HSA-597592
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Post-translational protein modification R-HSA-597592
STING mediated induction of host immune responses R-HSA-1834941
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Immune System R-HSA-168256
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
DNA Double-Strand Break Repair R-HSA-5693532
DNA Repair R-HSA-73894
IRF3-mediated induction of type I IFN R-HSA-3270619
Protein ubiquitination R-HSA-8852135
Metabolism of proteins R-HSA-392499
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Innate Immune System R-HSA-168249
DNA Repair R-HSA-73894
Immune System R-HSA-168256
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Innate Immune System R-HSA-168249
Metabolism of proteins R-HSA-392499
IRF3-mediated induction of type I IFN R-HSA-3270619
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
Post-translational protein modification R-HSA-597592
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
DNA Double-Strand Break Repair R-HSA-5693532
STING mediated induction of host immune responses R-HSA-1834941
Protein ubiquitination R-HSA-8852135

Expression Atlas ENSG00000253729
LRG display in Ensembl gene LRG_162
NCBI gene (formerly Entrezgene) 5591
GeneCards 9413
HGNC Symbol HGNC:9413
MIM gene 600899
MIM morbid 615966
UniProtKB Gene Name P78527
WikiGene 5591