Gene: MAP3K9
Ensembl ID : ENSG00000006432
Description: mitogen-activated protein kinase kinase kinase 9
Gene Synonyms: MEKK9,MLK1,PRKE1
1 APIs:
195 Possible Orthologues:

Expression Atlas ENSG00000006432
NCBI gene (formerly Entrezgene) 4293
GeneCards 6861
HGNC Symbol HGNC:6861
MIM gene 600136
UniProtKB Gene Name P80192
WikiGene 4293
Gene: LYN
Ensembl ID : ENSG00000254087
Description: LYN proto-oncogene, Src family tyrosine kinase
Gene Synonyms: JTK8
4 APIs:
197 Possible Orthologues:

Innate Immune System R-HSA-168249
Growth hormone receptor signaling R-HSA-982772
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Axon guidance R-HSA-422475
Adaptive Immune System R-HSA-1280218
CD22 mediated BCR regulation R-HSA-5690714
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Infectious disease R-HSA-5663205
Signaling by Erythropoietin R-HSA-9006335
Signaling by Interleukins R-HSA-449147
Cyclin D associated events in G1 R-HSA-69231
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Signaling by SCF-KIT R-HSA-1433557
Leishmania infection R-HSA-9658195
EPHB-mediated forward signaling R-HSA-3928662
Cell Cycle R-HSA-1640170
Leishmania parasite growth and survival R-HSA-9664433
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of signaling by CBL R-HSA-912631
Hemostasis R-HSA-109582
G1 Phase R-HSA-69236
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
CD209 (DC-SIGN) signaling R-HSA-5621575
Regulation of KIT signaling R-HSA-1433559
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Dectin-2 family R-HSA-5621480
CTLA4 inhibitory signaling R-HSA-389513
Parasite infection R-HSA-9664407
Erythropoietin activates STAT5 R-HSA-9027283
Cell Cycle, Mitotic R-HSA-69278
Signaling by CSF3 (G-CSF) R-HSA-9674555
EPHA-mediated growth cone collapse R-HSA-3928663
FCERI mediated Ca+2 mobilization R-HSA-2871809
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Leishmania phagocytosis R-HSA-9664417
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
FCGR3A-mediated phagocytosis R-HSA-9664422
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Platelet activation, signaling and aggregation R-HSA-76002
EPH-Ephrin signaling R-HSA-2682334
Disease R-HSA-1643685
Signaling by KIT in disease R-HSA-9669938
GPVI-mediated activation cascade R-HSA-114604
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Mitotic G1 phase and G1/S transition R-HSA-453279
FCERI mediated MAPK activation R-HSA-2871796
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Erythropoietin activates RAS R-HSA-9027284
PECAM1 interactions R-HSA-210990
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
FCERI mediated NF-kB activation R-HSA-2871837
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Costimulation by the CD28 family R-HSA-388841
C-type lectin receptors (CLRs) R-HSA-5621481
FCGR activation R-HSA-2029481
Cell surface interactions at the vascular wall R-HSA-202733
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Platelet Adhesion to exposed collagen R-HSA-75892
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
CD28 co-stimulation R-HSA-389356
Immune System R-HSA-168256
CD28 co-stimulation R-HSA-389356
FCGR activation R-HSA-2029481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Leishmania infection R-HSA-9658195
Dectin-2 family R-HSA-5621480
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EPHB-mediated forward signaling R-HSA-3928662
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Hemostasis R-HSA-109582
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated MAPK activation R-HSA-2871796
Regulation of signaling by CBL R-HSA-912631
Adaptive Immune System R-HSA-1280218
Signaling by CSF3 (G-CSF) R-HSA-9674555
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
G1 Phase R-HSA-69236
Erythropoietin activates RAS R-HSA-9027284
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
CD209 (DC-SIGN) signaling R-HSA-5621575
Erythropoietin activates STAT5 R-HSA-9027283
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
GPVI-mediated activation cascade R-HSA-114604
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Platelet Adhesion to exposed collagen R-HSA-75892
Signaling by Erythropoietin R-HSA-9006335
EPHA-mediated growth cone collapse R-HSA-3928663
Platelet activation, signaling and aggregation R-HSA-76002
EPH-Ephrin signaling R-HSA-2682334
Mitotic G1 phase and G1/S transition R-HSA-453279
Infectious disease R-HSA-5663205
CD22 mediated BCR regulation R-HSA-5690714
Axon guidance R-HSA-422475
Costimulation by the CD28 family R-HSA-388841
FCGR3A-mediated phagocytosis R-HSA-9664422
Disease R-HSA-1643685
PECAM1 interactions R-HSA-210990
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of KIT signaling R-HSA-1433559
Leishmania phagocytosis R-HSA-9664417
Signaling by KIT in disease R-HSA-9669938
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
FCERI mediated Ca+2 mobilization R-HSA-2871809
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Cyclin D associated events in G1 R-HSA-69231
Signaling by SCF-KIT R-HSA-1433557
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Leishmania parasite growth and survival R-HSA-9664433
Growth hormone receptor signaling R-HSA-982772
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
C-type lectin receptors (CLRs) R-HSA-5621481
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Parasite infection R-HSA-9664407
Cell surface interactions at the vascular wall R-HSA-202733
Nervous system development R-HSA-9675108
CTLA4 inhibitory signaling R-HSA-389513
Cell Cycle, Mitotic R-HSA-69278
Cyclin D associated events in G1 R-HSA-69231
Signaling by Interleukins R-HSA-449147
FCERI mediated Ca+2 mobilization R-HSA-2871809
Parasite infection R-HSA-9664407
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Nervous system development R-HSA-9675108
FCGR3A-mediated phagocytosis R-HSA-9664422
C-type lectin receptors (CLRs) R-HSA-5621481
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
FCERI mediated NF-kB activation R-HSA-2871837
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signal Transduction R-HSA-162582
Erythropoietin activates RAS R-HSA-9027284
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Platelet Adhesion to exposed collagen R-HSA-75892
EPHA-mediated growth cone collapse R-HSA-3928663
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
CTLA4 inhibitory signaling R-HSA-389513
Signaling by SCF-KIT R-HSA-1433557
Growth hormone receptor signaling R-HSA-982772
FCERI mediated MAPK activation R-HSA-2871796
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Leishmania parasite growth and survival R-HSA-9664433
Hemostasis R-HSA-109582
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Regulation of signaling by CBL R-HSA-912631
Disease R-HSA-1643685
Dectin-2 family R-HSA-5621480
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Platelet activation, signaling and aggregation R-HSA-76002
Immune System R-HSA-168256
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Leishmania infection R-HSA-9658195
CD22 mediated BCR regulation R-HSA-5690714
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by Erythropoietin R-HSA-9006335
Developmental Biology R-HSA-1266738
CD28 co-stimulation R-HSA-389356
Adaptive Immune System R-HSA-1280218
Erythropoietin activates STAT5 R-HSA-9027283
EPHB-mediated forward signaling R-HSA-3928662
Regulation of KIT signaling R-HSA-1433559
GPVI-mediated activation cascade R-HSA-114604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Costimulation by the CD28 family R-HSA-388841
Cytokine Signaling in Immune system R-HSA-1280215
Cell Cycle, Mitotic R-HSA-69278
G1 Phase R-HSA-69236
CD209 (DC-SIGN) signaling R-HSA-5621575
Mitotic G1 phase and G1/S transition R-HSA-453279
Infectious disease R-HSA-5663205
Cell Cycle R-HSA-1640170
Leishmania phagocytosis R-HSA-9664417
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by KIT in disease R-HSA-9669938
FCGR activation R-HSA-2029481
Innate Immune System R-HSA-168249
PECAM1 interactions R-HSA-210990
EPH-Ephrin signaling R-HSA-2682334
Signaling by CSF3 (G-CSF) R-HSA-9674555
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Leishmania phagocytosis R-HSA-9664417
Signaling by KIT in disease R-HSA-9669938
Costimulation by the CD28 family R-HSA-388841
Platelet activation, signaling and aggregation R-HSA-76002
EPHB-mediated forward signaling R-HSA-3928662
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Signal Transduction R-HSA-162582
Cyclin D associated events in G1 R-HSA-69231
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Parasite infection R-HSA-9664407
Innate Immune System R-HSA-168249
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by SCF-KIT R-HSA-1433557
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
GPVI-mediated activation cascade R-HSA-114604
Leishmania infection R-HSA-9658195
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Cell Cycle R-HSA-1640170
Erythropoietin activates RAS R-HSA-9027284
Dectin-2 family R-HSA-5621480
Growth hormone receptor signaling R-HSA-982772
Regulation of signaling by CBL R-HSA-912631
Erythropoietin activates STAT5 R-HSA-9027283
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Regulation of KIT signaling R-HSA-1433559
CD22 mediated BCR regulation R-HSA-5690714
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Nervous system development R-HSA-9675108
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Cell Cycle, Mitotic R-HSA-69278
CD28 co-stimulation R-HSA-389356
Signaling by CSF3 (G-CSF) R-HSA-9674555
FCGR3A-mediated phagocytosis R-HSA-9664422
Axon guidance R-HSA-422475
Infectious disease R-HSA-5663205
Leishmania parasite growth and survival R-HSA-9664433
FCERI mediated MAPK activation R-HSA-2871796
FCERI mediated Ca+2 mobilization R-HSA-2871809
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
FCGR activation R-HSA-2029481
Signaling by Interleukins R-HSA-449147
CTLA4 inhibitory signaling R-HSA-389513
Platelet Adhesion to exposed collagen R-HSA-75892
CD209 (DC-SIGN) signaling R-HSA-5621575
Cytokine Signaling in Immune system R-HSA-1280215
EPH-Ephrin signaling R-HSA-2682334
EPHA-mediated growth cone collapse R-HSA-3928663
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
G1 Phase R-HSA-69236
Adaptive Immune System R-HSA-1280218
Signaling by Erythropoietin R-HSA-9006335
PECAM1 interactions R-HSA-210990
Cell surface interactions at the vascular wall R-HSA-202733
Immune System R-HSA-168256
Hemostasis R-HSA-109582
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle, Mitotic R-HSA-69278
Signaling by CSF3 (G-CSF) R-HSA-9674555
Parasite infection R-HSA-9664407
G1 Phase R-HSA-69236
Signaling by the B Cell Receptor (BCR) R-HSA-983705
EPH-Ephrin signaling R-HSA-2682334
Mitotic G1 phase and G1/S transition R-HSA-453279
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
PECAM1 interactions R-HSA-210990
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Developmental Biology R-HSA-1266738
Hemostasis R-HSA-109582
Signaling by SCF-KIT R-HSA-1433557
Erythropoietin activates STAT5 R-HSA-9027283
Infectious disease R-HSA-5663205
Axon guidance R-HSA-422475
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
FCERI mediated Ca+2 mobilization R-HSA-2871809
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Growth hormone receptor signaling R-HSA-982772
CD209 (DC-SIGN) signaling R-HSA-5621575
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Signal Transduction R-HSA-162582
Regulation of signaling by CBL R-HSA-912631
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
CD22 mediated BCR regulation R-HSA-5690714
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
CD28 co-stimulation R-HSA-389356
Leishmania infection R-HSA-9658195
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
FCERI mediated NF-kB activation R-HSA-2871837
CTLA4 inhibitory signaling R-HSA-389513
GPVI-mediated activation cascade R-HSA-114604
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of KIT signaling R-HSA-1433559
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
Platelet Adhesion to exposed collagen R-HSA-75892
Cell surface interactions at the vascular wall R-HSA-202733
FCERI mediated MAPK activation R-HSA-2871796
Adaptive Immune System R-HSA-1280218
Erythropoietin activates RAS R-HSA-9027284
FCGR activation R-HSA-2029481
Signaling by KIT in disease R-HSA-9669938
Cyclin D associated events in G1 R-HSA-69231
Innate Immune System R-HSA-168249
Dectin-2 family R-HSA-5621480
Leishmania phagocytosis R-HSA-9664417
Signaling by Interleukins R-HSA-449147
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Erythropoietin R-HSA-9006335
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
FCGR3A-mediated phagocytosis R-HSA-9664422
EPHA-mediated growth cone collapse R-HSA-3928663
Cell Cycle R-HSA-1640170
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Costimulation by the CD28 family R-HSA-388841
Leishmania parasite growth and survival R-HSA-9664433
EPHB-mediated forward signaling R-HSA-3928662
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nervous system development R-HSA-9675108
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by Interleukins R-HSA-449147
FCGR3A-mediated phagocytosis R-HSA-9664422
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Cytokine Signaling in Immune system R-HSA-1280215
Infectious disease R-HSA-5663205
FCERI mediated MAPK activation R-HSA-2871796
Cell Cycle R-HSA-1640170
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
FCGR activation R-HSA-2029481
FCERI mediated Ca+2 mobilization R-HSA-2871809
Platelet activation, signaling and aggregation R-HSA-76002
Dectin-2 family R-HSA-5621480
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
CD209 (DC-SIGN) signaling R-HSA-5621575
G1 Phase R-HSA-69236
EPHA-mediated growth cone collapse R-HSA-3928663
Erythropoietin activates RAS R-HSA-9027284
Growth hormone receptor signaling R-HSA-982772
Disease R-HSA-1643685
Immune System R-HSA-168256
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
GPVI-mediated activation cascade R-HSA-114604
CD22 mediated BCR regulation R-HSA-5690714
Cell surface interactions at the vascular wall R-HSA-202733
Hemostasis R-HSA-109582
Mitotic G1 phase and G1/S transition R-HSA-453279
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
CTLA4 inhibitory signaling R-HSA-389513
Regulation of KIT signaling R-HSA-1433559
EPH-ephrin mediated repulsion of cells R-HSA-3928665
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulation of signaling by CBL R-HSA-912631
Adaptive Immune System R-HSA-1280218
Platelet Adhesion to exposed collagen R-HSA-75892
Leishmania phagocytosis R-HSA-9664417
Leishmania infection R-HSA-9658195
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by KIT in disease R-HSA-9669938
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Erythropoietin activates STAT5 R-HSA-9027283
Cell Cycle, Mitotic R-HSA-69278
Innate Immune System R-HSA-168249
Leishmania parasite growth and survival R-HSA-9664433
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Signaling by CSF3 (G-CSF) R-HSA-9674555
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Axon guidance R-HSA-422475
EPH-Ephrin signaling R-HSA-2682334
C-type lectin receptors (CLRs) R-HSA-5621481
Cyclin D associated events in G1 R-HSA-69231
Signaling by SCF-KIT R-HSA-1433557
PECAM1 interactions R-HSA-210990
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by Erythropoietin R-HSA-9006335
Parasite infection R-HSA-9664407
Costimulation by the CD28 family R-HSA-388841
EPHB-mediated forward signaling R-HSA-3928662
CD28 co-stimulation R-HSA-389356
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Leishmania infection R-HSA-9658195
Parasite infection R-HSA-9664407
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Axon guidance R-HSA-422475
Hemostasis R-HSA-109582
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
FCGR activation R-HSA-2029481
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Signaling by Interleukins R-HSA-449147
FCERI mediated Ca+2 mobilization R-HSA-2871809
Signaling by KIT in disease R-HSA-9669938
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by the B Cell Receptor (BCR) R-HSA-983705
EPHB-mediated forward signaling R-HSA-3928662
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
GPVI-mediated activation cascade R-HSA-114604
C-type lectin receptors (CLRs) R-HSA-5621481
CD209 (DC-SIGN) signaling R-HSA-5621575
Regulation of KIT signaling R-HSA-1433559
CD22 mediated BCR regulation R-HSA-5690714
EPHA-mediated growth cone collapse R-HSA-3928663
Signaling by CSF3 (G-CSF) R-HSA-9674555
Cytokine Signaling in Immune system R-HSA-1280215
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
FCERI mediated NF-kB activation R-HSA-2871837
Erythropoietin activates STAT5 R-HSA-9027283
G1 Phase R-HSA-69236
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Costimulation by the CD28 family R-HSA-388841
Mitotic G1 phase and G1/S transition R-HSA-453279
Growth hormone receptor signaling R-HSA-982772
EPH-ephrin mediated repulsion of cells R-HSA-3928665
CTLA4 inhibitory signaling R-HSA-389513
Infectious disease R-HSA-5663205
FCGR3A-mediated phagocytosis R-HSA-9664422
Cell surface interactions at the vascular wall R-HSA-202733
Nervous system development R-HSA-9675108
Signaling by Erythropoietin R-HSA-9006335
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Developmental Biology R-HSA-1266738
Signaling by SCF-KIT R-HSA-1433557
Leishmania parasite growth and survival R-HSA-9664433
Leishmania phagocytosis R-HSA-9664417
Innate Immune System R-HSA-168249
EPH-Ephrin signaling R-HSA-2682334
Cell Cycle R-HSA-1640170
Immune System R-HSA-168256
Regulation of signaling by CBL R-HSA-912631
Cell Cycle, Mitotic R-HSA-69278
Signal Transduction R-HSA-162582
Platelet Adhesion to exposed collagen R-HSA-75892
PECAM1 interactions R-HSA-210990
Platelet activation, signaling and aggregation R-HSA-76002
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
CD28 co-stimulation R-HSA-389356
Cyclin D associated events in G1 R-HSA-69231
FCERI mediated MAPK activation R-HSA-2871796
Adaptive Immune System R-HSA-1280218
Dectin-2 family R-HSA-5621480
Erythropoietin activates RAS R-HSA-9027284
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
C-type lectin receptors (CLRs) R-HSA-5621481
G1 Phase R-HSA-69236
CTLA4 inhibitory signaling R-HSA-389513
EPHB-mediated forward signaling R-HSA-3928662
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FCERI mediated MAPK activation R-HSA-2871796
Cyclin D associated events in G1 R-HSA-69231
EPH-Ephrin signaling R-HSA-2682334
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Hemostasis R-HSA-109582
Axon guidance R-HSA-422475
Leishmania phagocytosis R-HSA-9664417
Cell Cycle, Mitotic R-HSA-69278
FCGR activation R-HSA-2029481
Regulation of signaling by CBL R-HSA-912631
Regulation of KIT signaling R-HSA-1433559
FCERI mediated NF-kB activation R-HSA-2871837
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Innate Immune System R-HSA-168249
Cell Cycle R-HSA-1640170
CD209 (DC-SIGN) signaling R-HSA-5621575
Costimulation by the CD28 family R-HSA-388841
Signaling by Erythropoietin R-HSA-9006335
Adaptive Immune System R-HSA-1280218
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
GPVI-mediated activation cascade R-HSA-114604
Developmental Biology R-HSA-1266738
Platelet activation, signaling and aggregation R-HSA-76002
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Erythropoietin activates RAS R-HSA-9027284
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Leishmania infection R-HSA-9658195
Signaling by KIT in disease R-HSA-9669938
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Cell surface interactions at the vascular wall R-HSA-202733
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Infectious disease R-HSA-5663205
EPHA-mediated growth cone collapse R-HSA-3928663
FCERI mediated Ca+2 mobilization R-HSA-2871809
Parasite infection R-HSA-9664407
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Erythropoietin activates STAT5 R-HSA-9027283
CD28 co-stimulation R-HSA-389356
Signaling by CSF3 (G-CSF) R-HSA-9674555
Cytokine Signaling in Immune system R-HSA-1280215
CD22 mediated BCR regulation R-HSA-5690714
FCGR3A-mediated phagocytosis R-HSA-9664422
Disease R-HSA-1643685
Dectin-2 family R-HSA-5621480
PECAM1 interactions R-HSA-210990
Signaling by Interleukins R-HSA-449147
Mitotic G1 phase and G1/S transition R-HSA-453279
Platelet Adhesion to exposed collagen R-HSA-75892
Leishmania parasite growth and survival R-HSA-9664433
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Signaling by SCF-KIT R-HSA-1433557
Growth hormone receptor signaling R-HSA-982772
Signaling by Erythropoietin R-HSA-9006335
Platelet Adhesion to exposed collagen R-HSA-75892
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Leishmania phagocytosis R-HSA-9664417
FCGR3A-mediated phagocytosis R-HSA-9664422
CD28 co-stimulation R-HSA-389356
FCGR activation R-HSA-2029481
PECAM1 interactions R-HSA-210990
Cell Cycle, Mitotic R-HSA-69278
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Interleukins R-HSA-449147
Infectious disease R-HSA-5663205
Platelet activation, signaling and aggregation R-HSA-76002
CD22 mediated BCR regulation R-HSA-5690714
Signal Transduction R-HSA-162582
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Growth hormone receptor signaling R-HSA-982772
Leishmania infection R-HSA-9658195
Developmental Biology R-HSA-1266738
GPVI-mediated activation cascade R-HSA-114604
EPH-Ephrin signaling R-HSA-2682334
Disease R-HSA-1643685
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Erythropoietin activates RAS R-HSA-9027284
CTLA4 inhibitory signaling R-HSA-389513
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
FCERI mediated MAPK activation R-HSA-2871796
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by KIT in disease R-HSA-9669938
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated Ca+2 mobilization R-HSA-2871809
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell Cycle R-HSA-1640170
CD209 (DC-SIGN) signaling R-HSA-5621575
Signaling by SCF-KIT R-HSA-1433557
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
EPHA-mediated growth cone collapse R-HSA-3928663
EPHB-mediated forward signaling R-HSA-3928662
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
G1 Phase R-HSA-69236
Leishmania parasite growth and survival R-HSA-9664433
Immune System R-HSA-168256
Costimulation by the CD28 family R-HSA-388841
Regulation of signaling by CBL R-HSA-912631
Mitotic G1 phase and G1/S transition R-HSA-453279
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
Cyclin D associated events in G1 R-HSA-69231
Cell surface interactions at the vascular wall R-HSA-202733
Regulation of KIT signaling R-HSA-1433559
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Dectin-2 family R-HSA-5621480
FCERI mediated NF-kB activation R-HSA-2871837
Adaptive Immune System R-HSA-1280218
Signaling by CSF3 (G-CSF) R-HSA-9674555
Parasite infection R-HSA-9664407
Hemostasis R-HSA-109582
Erythropoietin activates STAT5 R-HSA-9027283
Hemostasis R-HSA-109582
Growth hormone receptor signaling R-HSA-982772
Signaling by KIT in disease R-HSA-9669938
Cell Cycle R-HSA-1640170
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Platelet Adhesion to exposed collagen R-HSA-75892
Signaling by SCF-KIT R-HSA-1433557
Parasite infection R-HSA-9664407
Leishmania phagocytosis R-HSA-9664417
Disease R-HSA-1643685
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Dectin-2 family R-HSA-5621480
CD28 co-stimulation R-HSA-389356
Erythropoietin activates STAT5 R-HSA-9027283
G1 Phase R-HSA-69236
Regulation of signaling by CBL R-HSA-912631
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Costimulation by the CD28 family R-HSA-388841
Erythropoietin activates RAS R-HSA-9027284
Cytokine Signaling in Immune system R-HSA-1280215
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
EPHB-mediated forward signaling R-HSA-3928662
Nervous system development R-HSA-9675108
Mitotic G1 phase and G1/S transition R-HSA-453279
FCERI mediated Ca+2 mobilization R-HSA-2871809
CTLA4 inhibitory signaling R-HSA-389513
CD209 (DC-SIGN) signaling R-HSA-5621575
GPVI-mediated activation cascade R-HSA-114604
Leishmania parasite growth and survival R-HSA-9664433
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Adaptive Immune System R-HSA-1280218
EPHA-mediated growth cone collapse R-HSA-3928663
Infectious disease R-HSA-5663205
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
C-type lectin receptors (CLRs) R-HSA-5621481
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Regulation of KIT signaling R-HSA-1433559
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Immune System R-HSA-168256
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
FCERI mediated MAPK activation R-HSA-2871796
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Innate Immune System R-HSA-168249
Leishmania infection R-HSA-9658195
CD22 mediated BCR regulation R-HSA-5690714
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Axon guidance R-HSA-422475
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by CSF3 (G-CSF) R-HSA-9674555
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Developmental Biology R-HSA-1266738
FCGR activation R-HSA-2029481
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Cyclin D associated events in G1 R-HSA-69231
FCGR3A-mediated IL10 synthesis R-HSA-9664323
EPH-Ephrin signaling R-HSA-2682334
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell Cycle, Mitotic R-HSA-69278
Signaling by Erythropoietin R-HSA-9006335
PECAM1 interactions R-HSA-210990
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Interleukins R-HSA-449147
FCERI mediated NF-kB activation R-HSA-2871837

Expression Atlas ENSG00000254087
NCBI gene (formerly Entrezgene) 4067
GeneCards 6735
HGNC Symbol HGNC:6735
MIM gene 165120
UniProtKB Gene Name P07948
WikiGene 4067
Ensembl ID : ENSG00000162889
Description: MAPK activated protein kinase 2
Gene Synonyms: MK2
1 APIs:
240 Possible Orthologues:

Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism R-HSA-1430728
Immune System R-HSA-168256
MyD88 dependent cascade initiated on endosome R-HSA-975155
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Cellular responses to stress R-HSA-2262752
Oxidative Stress Induced Senescence R-HSA-2559580
Interleukin-17 signaling R-HSA-448424
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Fatty acid metabolism R-HSA-8978868
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
MAP kinase activation R-HSA-450294
CREB phosphorylation R-HSA-199920
Signalling to RAS R-HSA-167044
Signaling by NTRKs R-HSA-166520
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll-like Receptor Cascades R-HSA-168898
MyD88 cascade initiated on plasma membrane R-HSA-975871
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Metabolism of lipids R-HSA-556833
Signaling by NTRK1 (TRKA) R-HSA-187037
Cellular Senescence R-HSA-2559583
Cytokine Signaling in Immune system R-HSA-1280215
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Metabolism of RNA R-HSA-8953854
Innate Immune System R-HSA-168249
MyD88-independent TLR4 cascade R-HSA-166166
Cellular response to heat stress R-HSA-3371556
TNF signaling R-HSA-75893
Arachidonic acid metabolism R-HSA-2142753
p38MAPK events R-HSA-171007
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cellular responses to stimuli R-HSA-8953897
Signalling to ERKs R-HSA-187687
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by VEGF R-HSA-194138
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Regulation of TNFR1 signaling R-HSA-5357905
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by NTRKs R-HSA-166520
Metabolism R-HSA-1430728
Toll-like Receptor Cascades R-HSA-168898
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
VEGFA-VEGFR2 Pathway R-HSA-4420097
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
MyD88 dependent cascade initiated on endosome R-HSA-975155
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signalling to RAS R-HSA-167044
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
MAP kinase activation R-HSA-450294
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by VEGF R-HSA-194138
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Death Receptor Signaling R-HSA-73887
Innate Immune System R-HSA-168249
Signalling to ERKs R-HSA-187687
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Fatty acid metabolism R-HSA-8978868
Arachidonic acid metabolism R-HSA-2142753
TNF signaling R-HSA-75893
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Interleukin-17 signaling R-HSA-448424
Immune System R-HSA-168256
MyD88 cascade initiated on plasma membrane R-HSA-975871
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Metabolism of RNA R-HSA-8953854
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular response to heat stress R-HSA-3371556
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
p38MAPK events R-HSA-171007
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Metabolism of lipids R-HSA-556833
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Oxidative Stress Induced Senescence R-HSA-2559580
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Regulation of TNFR1 signaling R-HSA-5357905
Signaling by Interleukins R-HSA-449147
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
CREB phosphorylation R-HSA-199920
Signaling by Interleukins R-HSA-449147
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Immune System R-HSA-168256
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Cytokine Signaling in Immune system R-HSA-1280215
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Interleukin-17 signaling R-HSA-448424
Metabolism of lipids R-HSA-556833
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Metabolism of RNA R-HSA-8953854
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Metabolism R-HSA-1430728
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stimuli R-HSA-8953897
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by NTRK1 (TRKA) R-HSA-187037
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by VEGF R-HSA-194138
MAP kinase activation R-HSA-450294
VEGFA-VEGFR2 Pathway R-HSA-4420097
MyD88 dependent cascade initiated on endosome R-HSA-975155
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signalling to ERKs R-HSA-187687
Signal Transduction R-HSA-162582
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
p38MAPK events R-HSA-171007
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Innate Immune System R-HSA-168249
Cellular Senescence R-HSA-2559583
Signaling by NTRKs R-HSA-166520
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Arachidonic acid metabolism R-HSA-2142753
Cellular responses to stress R-HSA-2262752
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll-like Receptor Cascades R-HSA-168898
Fatty acid metabolism R-HSA-8978868
CREB phosphorylation R-HSA-199920
Death Receptor Signaling R-HSA-73887
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TNF signaling R-HSA-75893
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signalling to RAS R-HSA-167044
Cellular Senescence R-HSA-2559583
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
Toll-like Receptor Cascades R-HSA-168898
Arachidonic acid metabolism R-HSA-2142753
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88-independent TLR4 cascade R-HSA-166166
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Metabolism of RNA R-HSA-8953854
Signaling by NTRK1 (TRKA) R-HSA-187037
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Immune System R-HSA-168256
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Oxidative Stress Induced Senescence R-HSA-2559580
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAP kinase activation R-HSA-450294
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by NTRKs R-HSA-166520
p38MAPK events R-HSA-171007
CREB phosphorylation R-HSA-199920
Fatty acid metabolism R-HSA-8978868
Signaling by VEGF R-HSA-194138
Regulation of TNFR1 signaling R-HSA-5357905
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Cellular responses to stress R-HSA-2262752
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
TNF signaling R-HSA-75893
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Cellular response to heat stress R-HSA-3371556
Signal Transduction R-HSA-162582
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Interleukin-17 signaling R-HSA-448424
Death Receptor Signaling R-HSA-73887
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
MyD88 cascade initiated on plasma membrane R-HSA-975871
Metabolism of lipids R-HSA-556833
Signalling to ERKs R-HSA-187687
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
VEGFA-VEGFR2 Pathway R-HSA-4420097
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signalling to RAS R-HSA-167044
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism R-HSA-1430728
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TNF signaling R-HSA-75893
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Immune System R-HSA-168256
Toll-like Receptor Cascades R-HSA-168898
Signaling by NTRKs R-HSA-166520
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signalling to ERKs R-HSA-187687
Arachidonic acid metabolism R-HSA-2142753
Cellular Senescence R-HSA-2559583
Regulation of TNFR1 signaling R-HSA-5357905
Cellular responses to stress R-HSA-2262752
VEGFA-VEGFR2 Pathway R-HSA-4420097
Interleukin-17 signaling R-HSA-448424
Signaling by NTRK1 (TRKA) R-HSA-187037
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Fatty acid metabolism R-HSA-8978868
Signaling by Interleukins R-HSA-449147
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signal Transduction R-HSA-162582
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Oxidative Stress Induced Senescence R-HSA-2559580
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Innate Immune System R-HSA-168249
Metabolism of RNA R-HSA-8953854
Signalling to RAS R-HSA-167044
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
CREB phosphorylation R-HSA-199920
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MAP kinase activation R-HSA-450294
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by VEGF R-HSA-194138
Cytokine Signaling in Immune system R-HSA-1280215
p38MAPK events R-HSA-171007
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MyD88-independent TLR4 cascade R-HSA-166166
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular response to heat stress R-HSA-3371556
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
MyD88 dependent cascade initiated on endosome R-HSA-975155
Arachidonic acid metabolism R-HSA-2142753
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
TNF signaling R-HSA-75893
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signaling by NTRKs R-HSA-166520
VEGFA-VEGFR2 Pathway R-HSA-4420097
Metabolism R-HSA-1430728
Fatty acid metabolism R-HSA-8978868
Cellular responses to stress R-HSA-2262752
Death Receptor Signaling R-HSA-73887
Signaling by VEGF R-HSA-194138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
p38MAPK events R-HSA-171007
Signalling to RAS R-HSA-167044
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Cellular Senescence R-HSA-2559583
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAP kinase activation R-HSA-450294
Regulation of TNFR1 signaling R-HSA-5357905
Signal Transduction R-HSA-162582
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 cascade initiated on plasma membrane R-HSA-975871
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Metabolism of lipids R-HSA-556833
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signalling to ERKs R-HSA-187687
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular responses to stimuli R-HSA-8953897
CREB phosphorylation R-HSA-199920
Metabolism of RNA R-HSA-8953854
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stress R-HSA-2262752
MAP kinase activation R-HSA-450294
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signalling to ERKs R-HSA-187687
Metabolism of lipids R-HSA-556833
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Innate Immune System R-HSA-168249
Interleukin-17 signaling R-HSA-448424
Signaling by NTRKs R-HSA-166520
Death Receptor Signaling R-HSA-73887
Cellular response to heat stress R-HSA-3371556
Signal Transduction R-HSA-162582
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Signaling by VEGF R-HSA-194138
Cellular Senescence R-HSA-2559583
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Fatty acid metabolism R-HSA-8978868
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Interleukins R-HSA-449147
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Immune System R-HSA-168256
Signalling to RAS R-HSA-167044
MyD88-independent TLR4 cascade R-HSA-166166
Metabolism of RNA R-HSA-8953854
Oxidative Stress Induced Senescence R-HSA-2559580
p38MAPK events R-HSA-171007
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
VEGFA-VEGFR2 Pathway R-HSA-4420097
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Metabolism R-HSA-1430728
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll-like Receptor Cascades R-HSA-168898
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Arachidonic acid metabolism R-HSA-2142753
Regulation of TNFR1 signaling R-HSA-5357905
CREB phosphorylation R-HSA-199920
TNF signaling R-HSA-75893
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Cellular responses to stimuli R-HSA-8953897
Signaling by VEGF R-HSA-194138
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signal Transduction R-HSA-162582
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Innate Immune System R-HSA-168249
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Metabolism of lipids R-HSA-556833
Signaling by NTRKs R-HSA-166520
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Interleukin-17 signaling R-HSA-448424
TNF signaling R-HSA-75893
Fatty acid metabolism R-HSA-8978868
Signaling by NTRK1 (TRKA) R-HSA-187037
Signalling to RAS R-HSA-167044
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
VEGFA-VEGFR2 Pathway R-HSA-4420097
MyD88-independent TLR4 cascade R-HSA-166166
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signalling to ERKs R-HSA-187687
MAP kinase activation R-HSA-450294
MyD88 dependent cascade initiated on endosome R-HSA-975155
Metabolism R-HSA-1430728
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cellular response to heat stress R-HSA-3371556
Arachidonic acid metabolism R-HSA-2142753
p38MAPK events R-HSA-171007
Toll-like Receptor Cascades R-HSA-168898
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of RNA R-HSA-8953854
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular Senescence R-HSA-2559583
Immune System R-HSA-168256
CREB phosphorylation R-HSA-199920
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Regulation of TNFR1 signaling R-HSA-5357905
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stress R-HSA-2262752
Oxidative Stress Induced Senescence R-HSA-2559580
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
Signaling by Interleukins R-HSA-449147
MyD88 dependent cascade initiated on endosome R-HSA-975155
Immune System R-HSA-168256
Toll-like Receptor Cascades R-HSA-168898
Regulation of TNFR1 signaling R-HSA-5357905
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
p38MAPK events R-HSA-171007
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Metabolism of lipids R-HSA-556833
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Arachidonic acid metabolism R-HSA-2142753
Cellular Senescence R-HSA-2559583
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Signaling by NTRK1 (TRKA) R-HSA-187037
Cellular response to heat stress R-HSA-3371556
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Death Receptor Signaling R-HSA-73887
Cellular responses to stress R-HSA-2262752
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signalling to RAS R-HSA-167044
Oxidative Stress Induced Senescence R-HSA-2559580
MyD88 cascade initiated on plasma membrane R-HSA-975871
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
MAP kinase activation R-HSA-450294
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
Signalling to ERKs R-HSA-187687
Fatty acid metabolism R-HSA-8978868
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
Signaling by VEGF R-HSA-194138
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
TNF signaling R-HSA-75893
Metabolism of RNA R-HSA-8953854
CREB phosphorylation R-HSA-199920
Signaling by NTRKs R-HSA-166520
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Arachidonic acid metabolism R-HSA-2142753
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Immune System R-HSA-168256
VEGFA-VEGFR2 Pathway R-HSA-4420097
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Death Receptor Signaling R-HSA-73887
MAP kinase activation R-HSA-450294
Signaling by NTRK1 (TRKA) R-HSA-187037
Signalling to ERKs R-HSA-187687
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
CREB phosphorylation R-HSA-199920
Signaling by NTRKs R-HSA-166520
Cellular response to heat stress R-HSA-3371556
Toll-like Receptor Cascades R-HSA-168898
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stress R-HSA-2262752
MyD88-independent TLR4 cascade R-HSA-166166
TNF signaling R-HSA-75893
MyD88 dependent cascade initiated on endosome R-HSA-975155
Regulation of TNFR1 signaling R-HSA-5357905
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
p38MAPK events R-HSA-171007
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Metabolism R-HSA-1430728
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
Interleukin-17 signaling R-HSA-448424
MyD88 cascade initiated on plasma membrane R-HSA-975871
Metabolism of RNA R-HSA-8953854
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by VEGF R-HSA-194138
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cytokine Signaling in Immune system R-HSA-1280215
Innate Immune System R-HSA-168249
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Cellular Senescence R-HSA-2559583
Signalling to RAS R-HSA-167044
Signal Transduction R-HSA-162582
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Metabolism of lipids R-HSA-556833
Fatty acid metabolism R-HSA-8978868
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164

Expression Atlas ENSG00000162889
NCBI gene (formerly Entrezgene) 9261
GeneCards 6887
HGNC Symbol HGNC:6887
MIM gene 602006
UniProtKB Gene Name P49137
WikiGene 9261
Gene: EGFR
Ensembl ID : ENSG00000146648
Description: epidermal growth factor receptor
Gene Synonyms: ERBB,ERBB1,ERRP
73 APIs:
286 Possible Orthologues:

Disease R-HSA-1643685
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
Downregulation of ERBB2 signaling R-HSA-8863795
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
Signaling by ERBB2 ECD mutants R-HSA-9665348
L1CAM interactions R-HSA-373760
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
HCMV Early Events R-HSA-9609690
GRB2 events in EGFR signaling R-HSA-179812
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PIP3 activates AKT signaling R-HSA-1257604
Membrane Trafficking R-HSA-199991
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
PI3K events in ERBB2 signaling R-HSA-1963642
Gene expression (Transcription) R-HSA-74160
EGFR interacts with phospholipase C-gamma R-HSA-212718
Signaling by Nuclear Receptors R-HSA-9006931
ESR-mediated signaling R-HSA-8939211
Developmental Biology R-HSA-1266738
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Intracellular signaling by second messengers R-HSA-9006925
Signal transduction by L1 R-HSA-445144
Extra-nuclear estrogen signaling R-HSA-9009391
Nervous system development R-HSA-9675108
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Signaling by PTK6 R-HSA-8848021
EGFR Transactivation by Gastrin R-HSA-2179392
G alpha (q) signalling events R-HSA-416476
Axon guidance R-HSA-422475
HCMV Infection R-HSA-9609646
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by EGFRvIII in Cancer R-HSA-5637812
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by GPCR R-HSA-372790
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Signal Transduction R-HSA-162582
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by ERBB2 in Cancer R-HSA-1227990
ERBB2 Regulates Cell Motility R-HSA-6785631
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by ERBB4 R-HSA-1236394
RNA Polymerase II Transcription R-HSA-73857
Signaling by EGFR in Cancer R-HSA-1643713
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB2 KD Mutants R-HSA-9664565
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by NOTCH3 R-HSA-9012852
PTK6 promotes HIF1A stabilization R-HSA-8857538
GPCR downstream signalling R-HSA-388396
Infectious disease R-HSA-5663205
SHC1 events in ERBB2 signaling R-HSA-1250196
SHC1 events in EGFR signaling R-HSA-180336
Vesicle-mediated transport R-HSA-5653656
GAB1 signalosome R-HSA-180292
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
PLCG1 events in ERBB2 signaling R-HSA-1251932
EGFR downregulation R-HSA-182971
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by ERBB2 R-HSA-1227986
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by EGFR R-HSA-177929
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by NOTCH R-HSA-157118
Generic Transcription Pathway R-HSA-212436
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SHC1 events in ERBB2 signaling R-HSA-1250196
EGFR interacts with phospholipase C-gamma R-HSA-212718
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by ERBB2 R-HSA-1227986
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by PTK6 R-HSA-8848021
GPCR downstream signalling R-HSA-388396
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
PI3K/AKT Signaling in Cancer R-HSA-2219528
Developmental Biology R-HSA-1266738
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by NOTCH R-HSA-157118
PIP3 activates AKT signaling R-HSA-1257604
Signal transduction by L1 R-HSA-445144
Membrane Trafficking R-HSA-199991
Signaling by ERBB4 R-HSA-1236394
Signaling by EGFRvIII in Cancer R-HSA-5637812
Vesicle-mediated transport R-HSA-5653656
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
L1CAM interactions R-HSA-373760
EGFR Transactivation by Gastrin R-HSA-2179392
Signaling by Nuclear Receptors R-HSA-9006931
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
ESR-mediated signaling R-HSA-8939211
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
HCMV Infection R-HSA-9609646
Signaling by ERBB2 in Cancer R-HSA-1227990
RNA Polymerase II Transcription R-HSA-73857
Signaling by EGFR R-HSA-177929
Signaling by GPCR R-HSA-372790
Axon guidance R-HSA-422475
GRB2 events in ERBB2 signaling R-HSA-1963640
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Infectious disease R-HSA-5663205
Signaling by NOTCH3 R-HSA-9012852
G alpha (q) signalling events R-HSA-416476
MAPK1/MAPK3 signaling R-HSA-5684996
Clathrin-mediated endocytosis R-HSA-8856828
Constitutive Signaling by EGFRvIII R-HSA-5637810
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
EGFR downregulation R-HSA-182971
GAB1 signalosome R-HSA-180292
GRB2 events in EGFR signaling R-HSA-179812
Downregulation of ERBB2 signaling R-HSA-8863795
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Nervous system development R-HSA-9675108
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Extra-nuclear estrogen signaling R-HSA-9009391
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ERBB2 ECD mutants R-HSA-9665348
PTK6 promotes HIF1A stabilization R-HSA-8857538
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
HCMV Early Events R-HSA-9609690
SHC1 events in EGFR signaling R-HSA-180336
PLCG1 events in ERBB2 signaling R-HSA-1251932
Signaling by ERBB2 KD Mutants R-HSA-9664565
Constitutive Signaling by EGFRvIII R-HSA-5637810
Infectious disease R-HSA-5663205
Signaling by Nuclear Receptors R-HSA-9006931
EGFR Transactivation by Gastrin R-HSA-2179392
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
SHC1 events in ERBB2 signaling R-HSA-1250196
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
ERBB2 Activates PTK6 Signaling R-HSA-8847993
PLCG1 events in ERBB2 signaling R-HSA-1251932
L1CAM interactions R-HSA-373760
EGFR downregulation R-HSA-182971
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by EGFR R-HSA-177929
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by EGFRvIII in Cancer R-HSA-5637812
Axon guidance R-HSA-422475
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
GRB2 events in EGFR signaling R-HSA-179812
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
ESR-mediated signaling R-HSA-8939211
RNA Polymerase II Transcription R-HSA-73857
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by EGFR in Cancer R-HSA-1643713
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by ERBB4 R-HSA-1236394
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Downregulation of ERBB2 signaling R-HSA-8863795
Vesicle-mediated transport R-HSA-5653656
GPCR downstream signalling R-HSA-388396
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
Signaling by PTK6 R-HSA-8848021
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
ERBB2 Regulates Cell Motility R-HSA-6785631
Generic Transcription Pathway R-HSA-212436
HCMV Early Events R-HSA-9609690
Signaling by NOTCH R-HSA-157118
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Developmental Biology R-HSA-1266738
Signal transduction by L1 R-HSA-445144
GRB2 events in ERBB2 signaling R-HSA-1963640
MAPK family signaling cascades R-HSA-5683057
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
RAF/MAP kinase cascade R-HSA-5673001
Signaling by ERBB2 ECD mutants R-HSA-9665348
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K events in ERBB2 signaling R-HSA-1963642
Gene expression (Transcription) R-HSA-74160
Membrane Trafficking R-HSA-199991
GAB1 signalosome R-HSA-180292
SHC1 events in EGFR signaling R-HSA-180336
Signaling by ERBB2 R-HSA-1227986
EGFR interacts with phospholipase C-gamma R-HSA-212718
Extra-nuclear estrogen signaling R-HSA-9009391
HCMV Infection R-HSA-9609646
MAPK1/MAPK3 signaling R-HSA-5684996
PTK6 promotes HIF1A stabilization R-HSA-8857538
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by NOTCH3 R-HSA-9012852
Developmental Biology R-HSA-1266738
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by EGFR in Cancer R-HSA-1643713
Constitutive Signaling by EGFRvIII R-HSA-5637810
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Infectious disease R-HSA-5663205
Signaling by GPCR R-HSA-372790
Signaling by ERBB2 KD Mutants R-HSA-9664565
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by EGFRvIII in Cancer R-HSA-5637812
G alpha (q) signalling events R-HSA-416476
Axon guidance R-HSA-422475
Vesicle-mediated transport R-HSA-5653656
HCMV Early Events R-HSA-9609690
Signaling by ERBB4 R-HSA-1236394
Signaling by EGFR R-HSA-177929
L1CAM interactions R-HSA-373760
GRB2 events in EGFR signaling R-HSA-179812
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH3 R-HSA-9012852
Disease R-HSA-1643685
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
GAB1 signalosome R-HSA-180292
SHC1 events in EGFR signaling R-HSA-180336
Signaling by PTK6 R-HSA-8848021
PLCG1 events in ERBB2 signaling R-HSA-1251932
PTK6 promotes HIF1A stabilization R-HSA-8857538
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH R-HSA-157118
Signal transduction by L1 R-HSA-445144
SHC1 events in ERBB2 signaling R-HSA-1250196
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by ERBB2 ECD mutants R-HSA-9665348
Intracellular signaling by second messengers R-HSA-9006925
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Membrane Trafficking R-HSA-199991
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
ERBB2 Regulates Cell Motility R-HSA-6785631
Generic Transcription Pathway R-HSA-212436
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by ERBB2 R-HSA-1227986
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Extra-nuclear estrogen signaling R-HSA-9009391
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Downregulation of ERBB2 signaling R-HSA-8863795
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EGFR downregulation R-HSA-182971
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI3K events in ERBB2 signaling R-HSA-1963642
EGFR interacts with phospholipase C-gamma R-HSA-212718
Signaling by Nuclear Receptors R-HSA-9006931
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
GPCR downstream signalling R-HSA-388396
ESR-mediated signaling R-HSA-8939211
EGFR Transactivation by Gastrin R-HSA-2179392
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
HCMV Infection R-HSA-9609646
Signaling by ERBB2 in Cancer R-HSA-1227990
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Vesicle-mediated transport R-HSA-5653656
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SHC1 events in EGFR signaling R-HSA-180336
ERBB2 Regulates Cell Motility R-HSA-6785631
RNA Polymerase II Transcription R-HSA-73857
PI3K/AKT Signaling in Cancer R-HSA-2219528
Generic Transcription Pathway R-HSA-212436
Signaling by ERBB2 ECD mutants R-HSA-9665348
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Signal Transduction R-HSA-162582
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
PLCG1 events in ERBB2 signaling R-HSA-1251932
GAB1 signalosome R-HSA-180292
HCMV Early Events R-HSA-9609690
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by Nuclear Receptors R-HSA-9006931
SHC1 events in ERBB2 signaling R-HSA-1250196
G alpha (q) signalling events R-HSA-416476
Signaling by PTK6 R-HSA-8848021
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signal transduction by L1 R-HSA-445144
Signaling by GPCR R-HSA-372790
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
PTK6 promotes HIF1A stabilization R-HSA-8857538
L1CAM interactions R-HSA-373760
Signaling by NOTCH R-HSA-157118
PI3K events in ERBB2 signaling R-HSA-1963642
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Infectious disease R-HSA-5663205
Signaling by EGFR in Cancer R-HSA-1643713
Disease R-HSA-1643685
ESR-mediated signaling R-HSA-8939211
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by EGFR R-HSA-177929
EGFR downregulation R-HSA-182971
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Developmental Biology R-HSA-1266738
EGFR Transactivation by Gastrin R-HSA-2179392
Intracellular signaling by second messengers R-HSA-9006925
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by ERBB2 KD Mutants R-HSA-9664565
Membrane Trafficking R-HSA-199991
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Extra-nuclear estrogen signaling R-HSA-9009391
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
GRB2 events in EGFR signaling R-HSA-179812
Signaling by ERBB4 R-HSA-1236394
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by EGFRvIII in Cancer R-HSA-5637812
Gene expression (Transcription) R-HSA-74160
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Downregulation of ERBB2 signaling R-HSA-8863795
Signaling by NOTCH3 R-HSA-9012852
Signaling by ERBB2 R-HSA-1227986
EGFR interacts with phospholipase C-gamma R-HSA-212718
HCMV Infection R-HSA-9609646
GPCR downstream signalling R-HSA-388396
Constitutive Signaling by EGFRvIII R-HSA-5637810
Axon guidance R-HSA-422475
EGFR interacts with phospholipase C-gamma R-HSA-212718
G alpha (q) signalling events R-HSA-416476
Signaling by ERBB4 R-HSA-1236394
SHC1 events in ERBB2 signaling R-HSA-1250196
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by Nuclear Receptors R-HSA-9006931
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Signaling by ERBB2 ECD mutants R-HSA-9665348
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by EGFR R-HSA-177929
Signaling by ERBB2 KD Mutants R-HSA-9664565
RAF/MAP kinase cascade R-HSA-5673001
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
GRB2 events in ERBB2 signaling R-HSA-1963640
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by ERBB2 R-HSA-1227986
ERBB2 Activates PTK6 Signaling R-HSA-8847993
PLCG1 events in ERBB2 signaling R-HSA-1251932
HCMV Early Events R-HSA-9609690
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PTK6 promotes HIF1A stabilization R-HSA-8857538
Signaling by ERBB2 in Cancer R-HSA-1227990
Signal transduction by L1 R-HSA-445144
ERBB2 Regulates Cell Motility R-HSA-6785631
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
GRB2 events in EGFR signaling R-HSA-179812
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Generic Transcription Pathway R-HSA-212436
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Axon guidance R-HSA-422475
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
ESR-mediated signaling R-HSA-8939211
Signaling by NOTCH R-HSA-157118
Signaling by EGFRvIII in Cancer R-HSA-5637812
Developmental Biology R-HSA-1266738
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Clathrin-mediated endocytosis R-HSA-8856828
Signaling by GPCR R-HSA-372790
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by PTK6 R-HSA-8848021
PI3K events in ERBB2 signaling R-HSA-1963642
Infectious disease R-HSA-5663205
L1CAM interactions R-HSA-373760
EGFR downregulation R-HSA-182971
EGFR Transactivation by Gastrin R-HSA-2179392
SHC1 events in EGFR signaling R-HSA-180336
Membrane Trafficking R-HSA-199991
Vesicle-mediated transport R-HSA-5653656
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Constitutive Signaling by EGFRvIII R-HSA-5637810
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by NOTCH3 R-HSA-9012852
Downregulation of ERBB2 signaling R-HSA-8863795
GAB1 signalosome R-HSA-180292
GPCR downstream signalling R-HSA-388396
HCMV Infection R-HSA-9609646
Signaling by Nuclear Receptors R-HSA-9006931
MAPK family signaling cascades R-HSA-5683057
ESR-mediated signaling R-HSA-8939211
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signaling by ERBB2 R-HSA-1227986
Signaling by NOTCH3 R-HSA-9012852
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by EGFR in Cancer R-HSA-1643713
HCMV Infection R-HSA-9609646
Membrane Trafficking R-HSA-199991
ERBB2 Regulates Cell Motility R-HSA-6785631
PI3K/AKT Signaling in Cancer R-HSA-2219528
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
SHC1 events in ERBB2 signaling R-HSA-1250196
PTK6 promotes HIF1A stabilization R-HSA-8857538
Signaling by NOTCH R-HSA-157118
GRB2 events in EGFR signaling R-HSA-179812
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Vesicle-mediated transport R-HSA-5653656
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by ERBB2 in Cancer R-HSA-1227990
Constitutive Signaling by EGFRvIII R-HSA-5637810
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
G alpha (q) signalling events R-HSA-416476
Generic Transcription Pathway R-HSA-212436
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Signal Transduction R-HSA-162582
L1CAM interactions R-HSA-373760
EGFR downregulation R-HSA-182971
Extra-nuclear estrogen signaling R-HSA-9009391
PI3K events in ERBB2 signaling R-HSA-1963642
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by EGFRvIII in Cancer R-HSA-5637812
Disease R-HSA-1643685
SHC1 events in EGFR signaling R-HSA-180336
Signaling by GPCR R-HSA-372790
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EGFR interacts with phospholipase C-gamma R-HSA-212718
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by PTK6 R-HSA-8848021
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
GRB2 events in ERBB2 signaling R-HSA-1963640
Clathrin-mediated endocytosis R-HSA-8856828
GAB1 signalosome R-HSA-180292
Downregulation of ERBB2 signaling R-HSA-8863795
PLCG1 events in ERBB2 signaling R-HSA-1251932
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by EGFR R-HSA-177929
GPCR downstream signalling R-HSA-388396
EGFR Transactivation by Gastrin R-HSA-2179392
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
Signal transduction by L1 R-HSA-445144
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
HCMV Early Events R-HSA-9609690
Signaling by ERBB4 R-HSA-1236394
Negative regulation of the PI3K/AKT network R-HSA-199418
Downregulation of ERBB2 signaling R-HSA-8863795
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K events in ERBB2 signaling R-HSA-1963642
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by EGFR R-HSA-177929
PTK6 promotes HIF1A stabilization R-HSA-8857538
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
GAB1 signalosome R-HSA-180292
RNA Polymerase II Transcription R-HSA-73857
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by ERBB4 R-HSA-1236394
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by EGFRvIII in Cancer R-HSA-5637812
Signaling by GPCR R-HSA-372790
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
GPCR downstream signalling R-HSA-388396
Signaling by EGFR in Cancer R-HSA-1643713
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH3 R-HSA-9012852
SHC1 events in ERBB2 signaling R-HSA-1250196
Signaling by ERBB2 in Cancer R-HSA-1227990
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal Transduction R-HSA-162582
Signaling by ERBB2 R-HSA-1227986
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
Extra-nuclear estrogen signaling R-HSA-9009391
Generic Transcription Pathway R-HSA-212436
L1CAM interactions R-HSA-373760
Signaling by ERBB2 KD Mutants R-HSA-9664565
Nervous system development R-HSA-9675108
MAPK1/MAPK3 signaling R-HSA-5684996
EGFR downregulation R-HSA-182971
G alpha (q) signalling events R-HSA-416476
Signal transduction by L1 R-HSA-445144
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
GRB2 events in ERBB2 signaling R-HSA-1963640
Intracellular signaling by second messengers R-HSA-9006925
EGFR interacts with phospholipase C-gamma R-HSA-212718
RAF/MAP kinase cascade R-HSA-5673001
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
PLCG1 events in ERBB2 signaling R-HSA-1251932
GRB2 events in EGFR signaling R-HSA-179812
EGFR Transactivation by Gastrin R-HSA-2179392
HCMV Early Events R-HSA-9609690
SHC1 events in EGFR signaling R-HSA-180336
Signaling by NOTCH R-HSA-157118
MAPK family signaling cascades R-HSA-5683057
Signaling by PTK6 R-HSA-8848021
Clathrin-mediated endocytosis R-HSA-8856828
Disease R-HSA-1643685
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Membrane Trafficking R-HSA-199991
Axon guidance R-HSA-422475
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Vesicle-mediated transport R-HSA-5653656
HCMV Infection R-HSA-9609646
ESR-mediated signaling R-HSA-8939211
Intracellular signaling by second messengers R-HSA-9006925
Nervous system development R-HSA-9675108
EGFR Transactivation by Gastrin R-HSA-2179392
PLCG1 events in ERBB2 signaling R-HSA-1251932
Signal transduction by L1 R-HSA-445144
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
GPCR downstream signalling R-HSA-388396
HCMV Infection R-HSA-9609646
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
MAPK1/MAPK3 signaling R-HSA-5684996
PIP3 activates AKT signaling R-HSA-1257604
Signaling by PTK6 R-HSA-8848021
EGFR interacts with phospholipase C-gamma R-HSA-212718
HCMV Early Events R-HSA-9609690
EGFR downregulation R-HSA-182971
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by ERBB4 R-HSA-1236394
Axon guidance R-HSA-422475
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
PTK6 promotes HIF1A stabilization R-HSA-8857538
GRB2 events in EGFR signaling R-HSA-179812
MAPK family signaling cascades R-HSA-5683057
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
RNA Polymerase II Transcription R-HSA-73857
Clathrin-mediated endocytosis R-HSA-8856828
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Downregulation of ERBB2 signaling R-HSA-8863795
Signaling by EGFR R-HSA-177929
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Nuclear Receptors R-HSA-9006931
Generic Transcription Pathway R-HSA-212436
SHC1 events in EGFR signaling R-HSA-180336
Vesicle-mediated transport R-HSA-5653656
Signaling by EGFR in Cancer R-HSA-1643713
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by NOTCH R-HSA-157118
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB2 in Cancer R-HSA-1227990
ERBB2 Regulates Cell Motility R-HSA-6785631
ESR-mediated signaling R-HSA-8939211
L1CAM interactions R-HSA-373760
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by NOTCH3 R-HSA-9012852
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
GAB1 signalosome R-HSA-180292
Signaling by GPCR R-HSA-372790
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by ERBB2 R-HSA-1227986
Signaling by ERBB2 KD Mutants R-HSA-9664565
Disease R-HSA-1643685
SHC1 events in ERBB2 signaling R-HSA-1250196
Gene expression (Transcription) R-HSA-74160
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Membrane Trafficking R-HSA-199991
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by EGFRvIII in Cancer R-HSA-5637812
Extra-nuclear estrogen signaling R-HSA-9009391
Constitutive Signaling by EGFRvIII R-HSA-5637810
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Infectious disease R-HSA-5663205
Signaling by EGFRvIII in Cancer R-HSA-5637812
Signaling by EGFR in Cancer R-HSA-1643713
Intracellular signaling by second messengers R-HSA-9006925
Downregulation of ERBB2 signaling R-HSA-8863795
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by NOTCH R-HSA-157118
EGFR downregulation R-HSA-182971
GRB2 events in ERBB2 signaling R-HSA-1963640
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by ERBB2 in Cancer R-HSA-1227990
Infectious disease R-HSA-5663205
Signaling by ERBB2 R-HSA-1227986
Generic Transcription Pathway R-HSA-212436
Clathrin-mediated endocytosis R-HSA-8856828
RNA Polymerase II Transcription R-HSA-73857
Signaling by ERBB4 R-HSA-1236394
PTK6 promotes HIF1A stabilization R-HSA-8857538
SHC1 events in ERBB2 signaling R-HSA-1250196
Disease R-HSA-1643685
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
ERBB2 Regulates Cell Motility R-HSA-6785631
Gene expression (Transcription) R-HSA-74160
Vesicle-mediated transport R-HSA-5653656
Axon guidance R-HSA-422475
Signaling by PTK6 R-HSA-8848021
HCMV Infection R-HSA-9609646
MAPK family signaling cascades R-HSA-5683057
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825
HCMV Early Events R-HSA-9609690
RAF/MAP kinase cascade R-HSA-5673001
EGFR interacts with phospholipase C-gamma R-HSA-212718
Membrane Trafficking R-HSA-199991
Constitutive Signaling by EGFRvIII R-HSA-5637810
PI3K events in ERBB2 signaling R-HSA-1963642
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
GAB1 signalosome R-HSA-180292
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signal transduction by L1 R-HSA-445144
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by GPCR R-HSA-372790
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
GPCR downstream signalling R-HSA-388396
Signaling by NOTCH3 R-HSA-9012852
Signal Transduction R-HSA-162582
EGFR Transactivation by Gastrin R-HSA-2179392
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303
L1CAM interactions R-HSA-373760
Signaling by EGFR R-HSA-177929
G alpha (q) signalling events R-HSA-416476
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Negative regulation of the PI3K/AKT network R-HSA-199418
PLCG1 events in ERBB2 signaling R-HSA-1251932
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
GRB2 events in EGFR signaling R-HSA-179812
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
ESR-mediated signaling R-HSA-8939211
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SHC1 events in EGFR signaling R-HSA-180336

Expression Atlas ENSG00000146648
LRG display in Ensembl gene LRG_304
NCBI gene (formerly Entrezgene) 1956
GeneCards 3236
HGNC Symbol HGNC:3236
MIM gene 131550
MIM morbid 616069
UniProtKB Gene Name Q504U8
WikiGene 1956
Gene: MKNK2
Ensembl ID : ENSG00000099875
Description: MAPK interacting serine/threonine kinase 2
Gene Synonyms: GPRK7,MNK2
1 APIs:
221 Possible Orthologues:

Expression Atlas ENSG00000099875
NCBI gene (formerly Entrezgene) 2872
GeneCards 7111
HGNC Symbol HGNC:7111
MIM gene 605069
UniProtKB Gene Name Q9NV89
WikiGene 2872
Gene: PDGFRA
Ensembl ID : ENSG00000134853
Description: platelet derived growth factor receptor alpha
Gene Synonyms: CD140A,GAS9,PDGFR2
29 APIs:
204 Possible Orthologues:

RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by PDGF R-HSA-186797
PI3K/AKT Signaling in Cancer R-HSA-2219528
Sunitinib-resistant PDGFR mutants R-HSA-9674401
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Imatinib-resistant PDGFR mutants R-HSA-9674396
Drug resistance of PDGFR mutants R-HSA-9674415
MAPK family signaling cascades R-HSA-5683057
PDGFR mutants bind TKIs R-HSA-9674428
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signal transduction R-HSA-186763
Signaling by PDGFR in disease R-HSA-9671555
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Intracellular signaling by second messengers R-HSA-9006925
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Downstream signal transduction R-HSA-186763
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Sunitinib-resistant PDGFR mutants R-HSA-9674401
RAF/MAP kinase cascade R-HSA-5673001
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Regorafenib-resistant PDGFR mutants R-HSA-9674403
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
Disease R-HSA-1643685
PDGFR mutants bind TKIs R-HSA-9674428
Imatinib-resistant PDGFR mutants R-HSA-9674396
PIP3 activates AKT signaling R-HSA-1257604
Signaling by PDGFR in disease R-HSA-9671555
Drug resistance of PDGFR mutants R-HSA-9674415
Signaling by PDGF R-HSA-186797
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
PI3K/AKT Signaling in Cancer R-HSA-2219528
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Signaling by PDGF R-HSA-186797
Signaling by PDGFR in disease R-HSA-9671555
Downstream signal transduction R-HSA-186763
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK family signaling cascades R-HSA-5683057
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Negative regulation of the PI3K/AKT network R-HSA-199418
Imatinib-resistant PDGFR mutants R-HSA-9674396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PDGFR mutants bind TKIs R-HSA-9674428
Disease R-HSA-1643685
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Drug resistance of PDGFR mutants R-HSA-9674415
Imatinib-resistant PDGFR mutants R-HSA-9674396
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Drug resistance of PDGFR mutants R-HSA-9674415
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by PDGFR in disease R-HSA-9671555
PDGFR mutants bind TKIs R-HSA-9674428
Disease R-HSA-1643685
Signaling by PDGF R-HSA-186797
Sorafenib-resistant PDGFR mutants R-HSA-9674404
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
Downstream signal transduction R-HSA-186763
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signal transduction R-HSA-186763
Signaling by PDGF R-HSA-186797
Signaling by PDGFR in disease R-HSA-9671555
RAF/MAP kinase cascade R-HSA-5673001
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Disease R-HSA-1643685
PDGFR mutants bind TKIs R-HSA-9674428
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal Transduction R-HSA-162582
Drug resistance of PDGFR mutants R-HSA-9674415
Imatinib-resistant PDGFR mutants R-HSA-9674396
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regorafenib-resistant PDGFR mutants R-HSA-9674403
MAPK family signaling cascades R-HSA-5683057
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PIP3 activates AKT signaling R-HSA-1257604
Signaling by PDGFR in disease R-HSA-9671555
Downstream signal transduction R-HSA-186763
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
Imatinib-resistant PDGFR mutants R-HSA-9674396
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
PDGFR mutants bind TKIs R-HSA-9674428
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by PDGF R-HSA-186797
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
PIP3 activates AKT signaling R-HSA-1257604
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
MAPK1/MAPK3 signaling R-HSA-5684996
Drug resistance of PDGFR mutants R-HSA-9674415
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGFR in disease R-HSA-9671555
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
PDGFR mutants bind TKIs R-HSA-9674428
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signal transduction R-HSA-186763
Drug resistance of PDGFR mutants R-HSA-9674415
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Imatinib-resistant PDGFR mutants R-HSA-9674396
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by PDGF R-HSA-186797
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGF R-HSA-186797
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Disease R-HSA-1643685
Drug resistance of PDGFR mutants R-HSA-9674415
PDGFR mutants bind TKIs R-HSA-9674428
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Downstream signal transduction R-HSA-186763
PIP3 activates AKT signaling R-HSA-1257604
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Imatinib-resistant PDGFR mutants R-HSA-9674396
MAPK family signaling cascades R-HSA-5683057
Signaling by PDGFR in disease R-HSA-9671555
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signal transduction R-HSA-186763
Sunitinib-resistant PDGFR mutants R-HSA-9674401
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK family signaling cascades R-HSA-5683057
Drug resistance of PDGFR mutants R-HSA-9674415
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Imatinib-resistant PDGFR mutants R-HSA-9674396
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
PDGFR mutants bind TKIs R-HSA-9674428
Signaling by PDGFR in disease R-HSA-9671555
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regorafenib-resistant PDGFR mutants R-HSA-9674403
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Signaling by PDGF R-HSA-186797
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAF/MAP kinase cascade R-HSA-5673001
Drug resistance of PDGFR mutants R-HSA-9674415
PDGFR mutants bind TKIs R-HSA-9674428
MAPK1/MAPK3 signaling R-HSA-5684996
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Downstream signal transduction R-HSA-186763
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Sunitinib-resistant PDGFR mutants R-HSA-9674401
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Imatinib-resistant PDGFR mutants R-HSA-9674396
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signal Transduction R-HSA-162582
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by PDGF R-HSA-186797
MAPK family signaling cascades R-HSA-5683057
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by PDGFR in disease R-HSA-9671555
Negative regulation of the PI3K/AKT network R-HSA-199418

Expression Atlas ENSG00000134853
LRG display in Ensembl gene LRG_309
NCBI gene (formerly Entrezgene) 5156
GeneCards 8803
HGNC Symbol HGNC:8803
MIM gene 173490
MIM morbid 607685
UniProtKB Gene Name P16234
WikiGene 5156
Gene: JAK2
Ensembl ID : ENSG00000096968
Description: Janus kinase 2
Gene Synonyms: JTK10
23 APIs:
265 Possible Orthologues:

G1 Phase R-HSA-69236
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-2 family signaling R-HSA-451927
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Interleukin-6 signaling R-HSA-1059683
Interleukin-6 family signaling R-HSA-6783589
Mitotic G1 phase and G1/S transition R-HSA-453279
Chromatin organization R-HSA-4839726
Erythropoietin activates RAS R-HSA-9027284
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Infectious disease R-HSA-5663205
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV Infections R-HSA-9679506
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-23 signaling R-HSA-9020933
Signaling by KIT in disease R-HSA-9669938
RAF activation R-HSA-5673000
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
G1 Phase R-HSA-69236
Interferon gamma signaling R-HSA-877300
Interleukin-12 signaling R-HSA-9020591
Interleukin-35 Signalling R-HSA-8984722
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Growth hormone receptor signaling R-HSA-982772
Cyclin D associated events in G1 R-HSA-69231
Interleukin-12 family signaling R-HSA-447115
MAPK family signaling cascades R-HSA-5683057
Signaling by Erythropoietin R-HSA-9006335
Prolactin receptor signaling R-HSA-1170546
Interleukin-27 signaling R-HSA-9020956
Disease R-HSA-1643685
Hemostasis R-HSA-109582
RMTs methylate histone arginines R-HSA-3214858
Potential therapeutics for SARS R-HSA-9679191
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Erythropoietin activates STAT5 R-HSA-9027283
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-20 family signaling R-HSA-8854691
Signaling by Leptin R-HSA-2586552
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK1 (ERK2) activation R-HSA-112411
Signaling by SCF-KIT R-HSA-1433557
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Oncogenic MAPK signaling R-HSA-6802957
Signaling by RAS mutants R-HSA-6802949
Immune System R-HSA-168256
Interferon Signaling R-HSA-913531
Signaling by Interleukins R-HSA-449147
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Chromatin modifying enzymes R-HSA-3247509
Regulation of IFNG signaling R-HSA-877312
Signaling by RAF1 mutants R-HSA-9656223
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Cell Cycle R-HSA-1640170
Interleukin receptor SHC signaling R-HSA-912526
Interleukin-2 family signaling R-HSA-451927
Signaling by Leptin R-HSA-2586552
Interleukin-6 family signaling R-HSA-6783589
Cell Cycle R-HSA-1640170
Signal Transduction R-HSA-162582
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Chromatin modifying enzymes R-HSA-3247509
Interleukin-12 family signaling R-HSA-447115
Growth hormone receptor signaling R-HSA-982772
Potential therapeutics for SARS R-HSA-9679191
Erythropoietin activates RAS R-HSA-9027284
Interferon Signaling R-HSA-913531
Interleukin-27 signaling R-HSA-9020956
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Interleukin-12 signaling R-HSA-9020591
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-23 signaling R-HSA-9020933
Interferon gamma signaling R-HSA-877300
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Regulation of IFNG signaling R-HSA-877312
Disease R-HSA-1643685
Interleukin-20 family signaling R-HSA-8854691
RAF-independent MAPK1/3 activation R-HSA-112409
Cyclin D associated events in G1 R-HSA-69231
Signaling by Erythropoietin R-HSA-9006335
Erythropoietin activates STAT5 R-HSA-9027283
MAPK family signaling cascades R-HSA-5683057
Signaling by RAF1 mutants R-HSA-9656223
Cytokine Signaling in Immune system R-HSA-1280215
Chromatin organization R-HSA-4839726
RMTs methylate histone arginines R-HSA-3214858
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
G1 Phase R-HSA-69236
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Interleukin-35 Signalling R-HSA-8984722
Factors involved in megakaryocyte development and platelet production R-HSA-983231
MAPK3 (ERK1) activation R-HSA-110056
Infectious disease R-HSA-5663205
MAPK1 (ERK2) activation R-HSA-112411
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Prolactin receptor signaling R-HSA-1170546
Mitotic G1 phase and G1/S transition R-HSA-453279
Oncogenic MAPK signaling R-HSA-6802957
Interleukin-6 signaling R-HSA-1059683
Signaling by RAS mutants R-HSA-6802949
Interleukin receptor SHC signaling R-HSA-912526
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
RAF activation R-HSA-5673000
Signaling downstream of RAS mutants R-HSA-9649948
Cell Cycle, Mitotic R-HSA-69278
Signaling by KIT in disease R-HSA-9669938
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hemostasis R-HSA-109582
Signaling by CSF3 (G-CSF) R-HSA-9674555
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
SARS-CoV Infections R-HSA-9679506
RAF/MAP kinase cascade R-HSA-5673001
Chromatin modifying enzymes R-HSA-3247509
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Cell Cycle R-HSA-1640170
Interleukin-12 family signaling R-HSA-447115
Interleukin-35 Signalling R-HSA-8984722
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Interleukin-6 signaling R-HSA-1059683
Immune System R-HSA-168256
Interleukin receptor SHC signaling R-HSA-912526
G1 Phase R-HSA-69236
Growth hormone receptor signaling R-HSA-982772
Interferon Signaling R-HSA-913531
Signaling by Erythropoietin R-HSA-9006335
RAF activation R-HSA-5673000
Erythropoietin activates STAT5 R-HSA-9027283
Erythropoietin activates RAS R-HSA-9027284
Interferon gamma signaling R-HSA-877300
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-20 family signaling R-HSA-8854691
Interleukin-6 family signaling R-HSA-6783589
Interleukin-27 signaling R-HSA-9020956
Infectious disease R-HSA-5663205
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of IFNG signaling R-HSA-877312
Potential therapeutics for SARS R-HSA-9679191
Prolactin receptor signaling R-HSA-1170546
MAPK3 (ERK1) activation R-HSA-110056
Signaling by SCF-KIT R-HSA-1433557
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Disease R-HSA-1643685
Interleukin-23 signaling R-HSA-9020933
Signal Transduction R-HSA-162582
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Signaling by RAS mutants R-HSA-6802949
Cell Cycle, Mitotic R-HSA-69278
Cytokine Signaling in Immune system R-HSA-1280215
SARS-CoV Infections R-HSA-9679506
MAPK family signaling cascades R-HSA-5683057
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Cyclin D associated events in G1 R-HSA-69231
RMTs methylate histone arginines R-HSA-3214858
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Interleukins R-HSA-449147
Signaling by KIT in disease R-HSA-9669938
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Oncogenic MAPK signaling R-HSA-6802957
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-12 signaling R-HSA-9020591
Signaling by Leptin R-HSA-2586552
Chromatin organization R-HSA-4839726
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-2 family signaling R-HSA-451927
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK1 (ERK2) activation R-HSA-112411
Hemostasis R-HSA-109582
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-23 signaling R-HSA-9020933
Signaling downstream of RAS mutants R-HSA-9649948
Potential therapeutics for SARS R-HSA-9679191
Interleukin-2 family signaling R-HSA-451927
Erythropoietin activates STAT5 R-HSA-9027283
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Prolactin receptor signaling R-HSA-1170546
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RMTs methylate histone arginines R-HSA-3214858
MAPK1 (ERK2) activation R-HSA-112411
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Interferon gamma signaling R-HSA-877300
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-20 family signaling R-HSA-8854691
Cell Cycle R-HSA-1640170
Hemostasis R-HSA-109582
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Interleukin-35 Signalling R-HSA-8984722
Cell Cycle, Mitotic R-HSA-69278
Signal Transduction R-HSA-162582
Chromatin modifying enzymes R-HSA-3247509
Disease R-HSA-1643685
Signaling by CSF3 (G-CSF) R-HSA-9674555
G1 Phase R-HSA-69236
Cyclin D associated events in G1 R-HSA-69231
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
Signaling by RAS mutants R-HSA-6802949
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Chromatin organization R-HSA-4839726
MAPK3 (ERK1) activation R-HSA-110056
Signaling by KIT in disease R-HSA-9669938
Interferon Signaling R-HSA-913531
Signaling by SCF-KIT R-HSA-1433557
MAPK family signaling cascades R-HSA-5683057
Interleukin-6 signaling R-HSA-1059683
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by BRAF and RAF1 fusions R-HSA-6802952
RAF-independent MAPK1/3 activation R-HSA-112409
Erythropoietin activates RAS R-HSA-9027284
Signaling by RAF1 mutants R-HSA-9656223
RAF activation R-HSA-5673000
Factors involved in megakaryocyte development and platelet production R-HSA-983231
SARS-CoV Infections R-HSA-9679506
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Regulation of IFNG signaling R-HSA-877312
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Oncogenic MAPK signaling R-HSA-6802957
Immune System R-HSA-168256
Signaling by Leptin R-HSA-2586552
Interleukin-12 family signaling R-HSA-447115
Interleukin-27 signaling R-HSA-9020956
Interleukin receptor SHC signaling R-HSA-912526
Mitotic G1 phase and G1/S transition R-HSA-453279
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-6 family signaling R-HSA-6783589
Signaling by Erythropoietin R-HSA-9006335
Interleukin-12 signaling R-HSA-9020591
Growth hormone receptor signaling R-HSA-982772
Interleukin-20 family signaling R-HSA-8854691
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Immune System R-HSA-168256
Regulation of IFNG signaling R-HSA-877312
Chromatin modifying enzymes R-HSA-3247509
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Chromatin organization R-HSA-4839726
Erythropoietin activates STAT5 R-HSA-9027283
Potential therapeutics for SARS R-HSA-9679191
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
SARS-CoV Infections R-HSA-9679506
Oncogenic MAPK signaling R-HSA-6802957
G1 Phase R-HSA-69236
Interleukin-12 family signaling R-HSA-447115
Cyclin D associated events in G1 R-HSA-69231
Interleukin-27 signaling R-HSA-9020956
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Erythropoietin activates RAS R-HSA-9027284
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Interleukin-6 signaling R-HSA-1059683
Signaling by Interleukins R-HSA-449147
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Hemostasis R-HSA-109582
Signaling by RAF1 mutants R-HSA-9656223
Cell Cycle R-HSA-1640170
Mitotic G1 phase and G1/S transition R-HSA-453279
Factors involved in megakaryocyte development and platelet production R-HSA-983231
RAF-independent MAPK1/3 activation R-HSA-112409
Growth hormone receptor signaling R-HSA-982772
Signaling by KIT in disease R-HSA-9669938
Cytokine Signaling in Immune system R-HSA-1280215
MAPK1 (ERK2) activation R-HSA-112411
RMTs methylate histone arginines R-HSA-3214858
Cell Cycle, Mitotic R-HSA-69278
Interferon gamma signaling R-HSA-877300
Signaling by Erythropoietin R-HSA-9006335
Prolactin receptor signaling R-HSA-1170546
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-35 Signalling R-HSA-8984722
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Interleukin receptor SHC signaling R-HSA-912526
Interferon Signaling R-HSA-913531
Signaling by RAS mutants R-HSA-6802949
Interleukin-2 family signaling R-HSA-451927
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-6 family signaling R-HSA-6783589
Disease R-HSA-1643685
MAPK family signaling cascades R-HSA-5683057
RAF activation R-HSA-5673000
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Signaling by BRAF and RAF1 fusions R-HSA-6802952
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling downstream of RAS mutants R-HSA-9649948
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Signaling by SCF-KIT R-HSA-1433557
Interleukin-12 signaling R-HSA-9020591
Signaling by Leptin R-HSA-2586552
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Infectious disease R-HSA-5663205
Interleukin-23 signaling R-HSA-9020933
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Leptin R-HSA-2586552
Hemostasis R-HSA-109582
Regulation of IFNG signaling R-HSA-877312
Growth hormone receptor signaling R-HSA-982772
RAF activation R-HSA-5673000
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Interferon Signaling R-HSA-913531
Prolactin receptor signaling R-HSA-1170546
Cell Cycle R-HSA-1640170
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by RAS mutants R-HSA-6802949
Signaling by KIT in disease R-HSA-9669938
Signaling by Interleukins R-HSA-449147
Cyclin D associated events in G1 R-HSA-69231
RMTs methylate histone arginines R-HSA-3214858
Interleukin-2 family signaling R-HSA-451927
SARS-CoV Infections R-HSA-9679506
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Erythropoietin R-HSA-9006335
Disease R-HSA-1643685
Erythropoietin activates STAT5 R-HSA-9027283
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Chromatin modifying enzymes R-HSA-3247509
Erythropoietin activates RAS R-HSA-9027284
Interleukin-12 family signaling R-HSA-447115
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-6 family signaling R-HSA-6783589
Infectious disease R-HSA-5663205
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Interleukin receptor SHC signaling R-HSA-912526
Signaling by BRAF and RAF1 fusions R-HSA-6802952
G1 Phase R-HSA-69236
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-23 signaling R-HSA-9020933
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
MAPK1 (ERK2) activation R-HSA-112411
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-12 signaling R-HSA-9020591
Interleukin-6 signaling R-HSA-1059683
Chromatin organization R-HSA-4839726
Immune System R-HSA-168256
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle, Mitotic R-HSA-69278
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Interleukin-27 signaling R-HSA-9020956
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Potential therapeutics for SARS R-HSA-9679191
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Signaling by CSF3 (G-CSF) R-HSA-9674555
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-20 family signaling R-HSA-8854691
Interleukin-35 Signalling R-HSA-8984722
Signaling by SCF-KIT R-HSA-1433557
Oncogenic MAPK signaling R-HSA-6802957
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
MAPK1/MAPK3 signaling R-HSA-5684996
Interferon gamma signaling R-HSA-877300
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signaling by RAF1 mutants R-HSA-9656223
Signal Transduction R-HSA-162582
Interleukin-6 family signaling R-HSA-6783589
Cell Cycle, Mitotic R-HSA-69278
Interleukin-6 signaling R-HSA-1059683
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin receptor SHC signaling R-HSA-912526
Interleukin-23 signaling R-HSA-9020933
Signaling by Leptin R-HSA-2586552
Cyclin D associated events in G1 R-HSA-69231
RAF-independent MAPK1/3 activation R-HSA-112409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-12 signaling R-HSA-9020591
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Cytokine Signaling in Immune system R-HSA-1280215
Chromatin modifying enzymes R-HSA-3247509
Oncogenic MAPK signaling R-HSA-6802957
MAPK1 (ERK2) activation R-HSA-112411
Interleukin-20 family signaling R-HSA-8854691
Signaling by Erythropoietin R-HSA-9006335
Interferon gamma signaling R-HSA-877300
Hemostasis R-HSA-109582
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Interleukin-2 family signaling R-HSA-451927
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Erythropoietin activates RAS R-HSA-9027284
Prolactin receptor signaling R-HSA-1170546
Regulation of IFNG signaling R-HSA-877312
Interleukin-27 signaling R-HSA-9020956
RAF/MAP kinase cascade R-HSA-5673001
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Growth hormone receptor signaling R-HSA-982772
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by KIT in disease R-HSA-9669938
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
SARS-CoV Infections R-HSA-9679506
RMTs methylate histone arginines R-HSA-3214858
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Chromatin organization R-HSA-4839726
Signaling by RAS mutants R-HSA-6802949
Infectious disease R-HSA-5663205
Interferon Signaling R-HSA-913531
Interleukin-12 family signaling R-HSA-447115
Potential therapeutics for SARS R-HSA-9679191
Mitotic G1 phase and G1/S transition R-HSA-453279
Erythropoietin activates STAT5 R-HSA-9027283
MAPK family signaling cascades R-HSA-5683057
Cell Cycle R-HSA-1640170
Interleukin-35 Signalling R-HSA-8984722
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
MAPK3 (ERK1) activation R-HSA-110056
RAF activation R-HSA-5673000
G1 Phase R-HSA-69236
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Disease R-HSA-1643685
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Infectious disease R-HSA-5663205
Cell Cycle, Mitotic R-HSA-69278
Interferon Signaling R-HSA-913531
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-23 signaling R-HSA-9020933
G1 Phase R-HSA-69236
Potential therapeutics for SARS R-HSA-9679191
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-12 family signaling R-HSA-447115
Signaling by KIT in disease R-HSA-9669938
Disease R-HSA-1643685
Interleukin-12 signaling R-HSA-9020591
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signal Transduction R-HSA-162582
Interleukin-35 Signalling R-HSA-8984722
Chromatin organization R-HSA-4839726
Cyclin D associated events in G1 R-HSA-69231
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Signaling by RAF1 mutants R-HSA-9656223
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Oncogenic MAPK signaling R-HSA-6802957
Interleukin receptor SHC signaling R-HSA-912526
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
RMTs methylate histone arginines R-HSA-3214858
Chromatin modifying enzymes R-HSA-3247509
MAPK3 (ERK1) activation R-HSA-110056
RAF activation R-HSA-5673000
Signaling by Interleukins R-HSA-449147
Cell Cycle R-HSA-1640170
Signaling by Erythropoietin R-HSA-9006335
Hemostasis R-HSA-109582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by CSF3 (G-CSF) R-HSA-9674555
Growth hormone receptor signaling R-HSA-982772
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Interleukin-20 family signaling R-HSA-8854691
Mitotic G1 phase and G1/S transition R-HSA-453279
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of IFNG signaling R-HSA-877312
Prolactin receptor signaling R-HSA-1170546
MAPK1 (ERK2) activation R-HSA-112411
Interleukin-27 signaling R-HSA-9020956
MAPK family signaling cascades R-HSA-5683057
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
RAF-independent MAPK1/3 activation R-HSA-112409
RAF/MAP kinase cascade R-HSA-5673001
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Interleukin-6 family signaling R-HSA-6783589
Interleukin-6 signaling R-HSA-1059683
SARS-CoV Infections R-HSA-9679506
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Interleukin-2 family signaling R-HSA-451927
MAPK1/MAPK3 signaling R-HSA-5684996
Interferon gamma signaling R-HSA-877300
Signaling by SCF-KIT R-HSA-1433557
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Immune System R-HSA-168256
Erythropoietin activates RAS R-HSA-9027284
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by RAS mutants R-HSA-6802949
Signaling by Leptin R-HSA-2586552
Erythropoietin activates STAT5 R-HSA-9027283
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Growth hormone receptor signaling R-HSA-982772
Signaling by KIT in disease R-HSA-9669938
Interleukin-20 family signaling R-HSA-8854691
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Disease R-HSA-1643685
Interleukin-6 family signaling R-HSA-6783589
Interleukin-2 family signaling R-HSA-451927
Interleukin-12 signaling R-HSA-9020591
Interleukin-6 signaling R-HSA-1059683
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Interleukin receptor SHC signaling R-HSA-912526
Erythropoietin activates STAT5 R-HSA-9027283
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Chromatin organization R-HSA-4839726
Signal Transduction R-HSA-162582
G1 Phase R-HSA-69236
Interleukin-27 signaling R-HSA-9020956
Prolactin receptor signaling R-HSA-1170546
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-12 family signaling R-HSA-447115
Signaling by Interleukins R-HSA-449147
Signaling downstream of RAS mutants R-HSA-9649948
Immune System R-HSA-168256
MAPK1 (ERK2) activation R-HSA-112411
Cell Cycle R-HSA-1640170
Signaling by Erythropoietin R-HSA-9006335
RMTs methylate histone arginines R-HSA-3214858
Interleukin-23 signaling R-HSA-9020933
Infectious disease R-HSA-5663205
RAF activation R-HSA-5673000
Signaling by Leptin R-HSA-2586552
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Hemostasis R-HSA-109582
Interferon gamma signaling R-HSA-877300
Interleukin-35 Signalling R-HSA-8984722
MAPK1/MAPK3 signaling R-HSA-5684996
Cyclin D associated events in G1 R-HSA-69231
Signaling by RAS mutants R-HSA-6802949
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
Potential therapeutics for SARS R-HSA-9679191
MAPK family signaling cascades R-HSA-5683057
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Regulation of IFNG signaling R-HSA-877312
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
SARS-CoV Infections R-HSA-9679506
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Interferon Signaling R-HSA-913531
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK3 (ERK1) activation R-HSA-110056
Erythropoietin activates RAS R-HSA-9027284
Signaling by RAF1 mutants R-HSA-9656223
Chromatin modifying enzymes R-HSA-3247509
Oncogenic MAPK signaling R-HSA-6802957
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by SCF-KIT R-HSA-1433557
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Interleukin-6 signaling R-HSA-1059683
Chromatin organization R-HSA-4839726
Signaling by KIT in disease R-HSA-9669938
Interleukin-23 signaling R-HSA-9020933
RAF activation R-HSA-5673000
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Mitotic G1 phase and G1/S transition R-HSA-453279
MAPK1 (ERK2) activation R-HSA-112411
Interferon Signaling R-HSA-913531
Signaling by RAS mutants R-HSA-6802949
Interferon gamma signaling R-HSA-877300
Infectious disease R-HSA-5663205
MAPK1/MAPK3 signaling R-HSA-5684996
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
RAF-independent MAPK1/3 activation R-HSA-112409
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Interleukin-2 family signaling R-HSA-451927
Interleukin-35 Signalling R-HSA-8984722
Interleukin-12 signaling R-HSA-9020591
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Potential therapeutics for SARS R-HSA-9679191
Signaling by Interleukins R-HSA-449147
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Prolactin receptor signaling R-HSA-1170546
Regulation of IFNG signaling R-HSA-877312
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Signaling by Leptin R-HSA-2586552
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277
Interleukin-12 family signaling R-HSA-447115
Erythropoietin activates STAT5 R-HSA-9027283
Signaling downstream of RAS mutants R-HSA-9649948
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Hemostasis R-HSA-109582
Interleukin-20 family signaling R-HSA-8854691
Signaling by RAF1 mutants R-HSA-9656223
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cyclin D associated events in G1 R-HSA-69231
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by CSF3 (G-CSF) R-HSA-9674555
Disease R-HSA-1643685
Interleukin-27 signaling R-HSA-9020956
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
Growth hormone receptor signaling R-HSA-982772
RMTs methylate histone arginines R-HSA-3214858
SARS-CoV Infections R-HSA-9679506
Interleukin receptor SHC signaling R-HSA-912526
Oncogenic MAPK signaling R-HSA-6802957
Cell Cycle R-HSA-1640170
Chromatin modifying enzymes R-HSA-3247509
Signaling by SCF-KIT R-HSA-1433557
Interleukin-6 family signaling R-HSA-6783589
Erythropoietin activates RAS R-HSA-9027284
Immune System R-HSA-168256
Signaling by Erythropoietin R-HSA-9006335

Expression Atlas ENSG00000096968
LRG display in Ensembl gene LRG_612
NCBI gene (formerly Entrezgene) 3717
GeneCards 6192
HGNC Symbol HGNC:6192
MIM gene 147796
MIM morbid 614521
UniProtKB Gene Name O60674
WikiGene 3717
Gene: MAP3K11
Ensembl ID : ENSG00000173327
Description: mitogen-activated protein kinase kinase kinase 11
Gene Synonyms: MEKK11,MLK3,PTK1,SPRK
1 APIs:
184 Possible Orthologues:

RAF activation R-HSA-5673000
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHOV GTPase cycle R-HSA-9013424
RAF/MAP kinase cascade R-HSA-5673001
Oncogenic MAPK signaling R-HSA-6802957
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
RHO GTPase cycle R-HSA-9012999
Signaling by RAS mutants R-HSA-6802949
Disease R-HSA-1643685
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
RHOG GTPase cycle R-HSA-9013408
MAPK family signaling cascades R-HSA-5683057
CDC42 GTPase cycle R-HSA-9013148
Signaling downstream of RAS mutants R-HSA-9649948
RAF activation R-HSA-5673000
MAPK1/MAPK3 signaling R-HSA-5684996
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHOV GTPase cycle R-HSA-9013424
MAPK family signaling cascades R-HSA-5683057
Signaling by RAS mutants R-HSA-6802949
RAF/MAP kinase cascade R-HSA-5673001
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
CDC42 GTPase cycle R-HSA-9013148
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
RHOG GTPase cycle R-HSA-9013408
RHO GTPase cycle R-HSA-9012999
RAF activation R-HSA-5673000
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Rho GTPases R-HSA-194315
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling downstream of RAS mutants R-HSA-9649948
Oncogenic MAPK signaling R-HSA-6802957
Disease R-HSA-1643685
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RAF activation R-HSA-5673000
Signal Transduction R-HSA-162582
RAF/MAP kinase cascade R-HSA-5673001
RHO GTPase cycle R-HSA-9012999
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
CDC42 GTPase cycle R-HSA-9013148
Signaling by RAS mutants R-HSA-6802949
RHOG GTPase cycle R-HSA-9013408
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHOV GTPase cycle R-HSA-9013424
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by Rho GTPases R-HSA-194315
Disease R-HSA-1643685
Oncogenic MAPK signaling R-HSA-6802957
Oncogenic MAPK signaling R-HSA-6802957
Signaling downstream of RAS mutants R-HSA-9649948
Signal Transduction R-HSA-162582
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RHOG GTPase cycle R-HSA-9013408
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF activation R-HSA-5673000
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Rho GTPases R-HSA-194315
RHO GTPase cycle R-HSA-9012999
RAF/MAP kinase cascade R-HSA-5673001
CDC42 GTPase cycle R-HSA-9013148
RHOV GTPase cycle R-HSA-9013424
Signaling by RAS mutants R-HSA-6802949
RHO GTPase cycle R-HSA-9012999
Signal Transduction R-HSA-162582
RHOV GTPase cycle R-HSA-9013424
Signaling downstream of RAS mutants R-HSA-9649948
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
MAPK family signaling cascades R-HSA-5683057
Signaling by RAS mutants R-HSA-6802949
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Oncogenic MAPK signaling R-HSA-6802957
CDC42 GTPase cycle R-HSA-9013148
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signaling by Rho GTPases R-HSA-194315
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RHOG GTPase cycle R-HSA-9013408
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
CDC42 GTPase cycle R-HSA-9013148
Signaling by RAS mutants R-HSA-6802949
Signaling downstream of RAS mutants R-HSA-9649948
MAPK1/MAPK3 signaling R-HSA-5684996
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RHOG GTPase cycle R-HSA-9013408
Signaling by Rho GTPases R-HSA-194315
RHOV GTPase cycle R-HSA-9013424
Disease R-HSA-1643685
RHO GTPase cycle R-HSA-9012999
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
RAF activation R-HSA-5673000
Signal Transduction R-HSA-162582
Oncogenic MAPK signaling R-HSA-6802957
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
CDC42 GTPase cycle R-HSA-9013148
RHOG GTPase cycle R-HSA-9013408
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
MAPK family signaling cascades R-HSA-5683057
Oncogenic MAPK signaling R-HSA-6802957
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
RHOV GTPase cycle R-HSA-9013424
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Signaling by RAS mutants R-HSA-6802949
Signaling downstream of RAS mutants R-HSA-9649948
RHO GTPase cycle R-HSA-9012999
Signaling by Rho GTPases R-HSA-194315
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF activation R-HSA-5673000
Oncogenic MAPK signaling R-HSA-6802957
Disease R-HSA-1643685
Signaling downstream of RAS mutants R-HSA-9649948
RAF activation R-HSA-5673000
RAF/MAP kinase cascade R-HSA-5673001
Signaling by RAS mutants R-HSA-6802949
RHOV GTPase cycle R-HSA-9013424
RHO GTPase cycle R-HSA-9012999
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
CDC42 GTPase cycle R-HSA-9013148
RHOG GTPase cycle R-HSA-9013408
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Oncogenic MAPK signaling R-HSA-6802957
Disease R-HSA-1643685
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
CDC42 GTPase cycle R-HSA-9013148
Signal Transduction R-HSA-162582
RAF activation R-HSA-5673000
Signaling downstream of RAS mutants R-HSA-9649948
RHOV GTPase cycle R-HSA-9013424
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Rho GTPases R-HSA-194315
RAF/MAP kinase cascade R-HSA-5673001
RHO GTPase cycle R-HSA-9012999
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHOG GTPase cycle R-HSA-9013408
Signaling by RAS mutants R-HSA-6802949
MAPK family signaling cascades R-HSA-5683057
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542

Expression Atlas ENSG00000173327
NCBI gene (formerly Entrezgene) 4296
GeneCards 6850
HGNC Symbol HGNC:6850
MIM gene 600050
UniProtKB Gene Name Q16584
WikiGene 4296