Gene: ERBB2
Ensembl ID : ENSG00000141736
Description: erb-b2 receptor tyrosine kinase 2
Gene Synonyms: C-ERB-2,C-ERB2,CD340,HER-2,HER2,MLN-19,NEU,NGL,P185(ERBB2)
39 APIs:
200 Possible Orthologues:

Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Drug resistance in ERBB2 KD mutants R-HSA-9665230
ERBB2 Regulates Cell Motility R-HSA-6785631
PI3K events in ERBB2 signaling R-HSA-1963642
Disease R-HSA-1643685
Signaling by ERBB2 KD Mutants R-HSA-9664565
Intracellular signaling by second messengers R-HSA-9006925
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Sema4D in semaphorin signaling R-HSA-400685
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Downregulation of ERBB2 signaling R-HSA-8863795
Signaling by ERBB2 ECD mutants R-HSA-9665348
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
SHC1 events in ERBB2 signaling R-HSA-1250196
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
PLCG1 events in ERBB2 signaling R-HSA-1251932
Signaling by ERBB2 in Cancer R-HSA-1227990
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signaling by ERBB2 R-HSA-1227986
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
GRB2 events in ERBB2 signaling R-HSA-1963640
MAPK1/MAPK3 signaling R-HSA-5684996
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Generic Transcription Pathway R-HSA-212436
GRB7 events in ERBB2 signaling R-HSA-1306955
Nervous system development R-HSA-9675108
RAF/MAP kinase cascade R-HSA-5673001
RNA Polymerase II Transcription R-HSA-73857
Axon guidance R-HSA-422475
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
MAPK family signaling cascades R-HSA-5683057
Signaling by PTK6 R-HSA-8848021
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Semaphorin interactions R-HSA-373755
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
PI3K/AKT Signaling in Cancer R-HSA-2219528
Negative regulation of the PI3K/AKT network R-HSA-199418
Developmental Biology R-HSA-1266738
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
MAPK family signaling cascades R-HSA-5683057
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
RNA Polymerase II Transcription R-HSA-73857
SHC1 events in ERBB2 signaling R-HSA-1250196
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by ERBB2 KD Mutants R-HSA-9664565
PI3K events in ERBB2 signaling R-HSA-1963642
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
GRB7 events in ERBB2 signaling R-HSA-1306955
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by ERBB2 in Cancer R-HSA-1227990
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Nervous system development R-HSA-9675108
PI3K/AKT Signaling in Cancer R-HSA-2219528
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Semaphorin interactions R-HSA-373755
Intracellular signaling by second messengers R-HSA-9006925
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
RAF/MAP kinase cascade R-HSA-5673001
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Sema4D in semaphorin signaling R-HSA-400685
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Downregulation of ERBB2 signaling R-HSA-8863795
Disease R-HSA-1643685
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
GRB2 events in ERBB2 signaling R-HSA-1963640
MAPK1/MAPK3 signaling R-HSA-5684996
PLCG1 events in ERBB2 signaling R-HSA-1251932
Axon guidance R-HSA-422475
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by PTK6 R-HSA-8848021
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Signaling by ERBB2 R-HSA-1227986
RAF/MAP kinase cascade R-HSA-5673001
Downregulation of ERBB2 signaling R-HSA-8863795
Signal Transduction R-HSA-162582
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by PTK6 R-HSA-8848021
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
SHC1 events in ERBB2 signaling R-HSA-1250196
Signaling by ERBB2 KD Mutants R-HSA-9664565
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Sema4D in semaphorin signaling R-HSA-400685
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by ERBB2 in Cancer R-HSA-1227990
PI3K events in ERBB2 signaling R-HSA-1963642
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Nervous system development R-HSA-9675108
PLCG1 events in ERBB2 signaling R-HSA-1251932
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
Signaling by ERBB2 R-HSA-1227986
Generic Transcription Pathway R-HSA-212436
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
MAPK family signaling cascades R-HSA-5683057
Developmental Biology R-HSA-1266738
Signaling by ERBB2 ECD mutants R-HSA-9665348
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Drug resistance in ERBB2 KD mutants R-HSA-9665230
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
Gene expression (Transcription) R-HSA-74160
GRB7 events in ERBB2 signaling R-HSA-1306955
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
PI3K/AKT Signaling in Cancer R-HSA-2219528
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
PIP3 activates AKT signaling R-HSA-1257604
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
GRB2 events in ERBB2 signaling R-HSA-1963640
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Semaphorin interactions R-HSA-373755
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
ERBB2 Regulates Cell Motility R-HSA-6785631
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Signal Transduction R-HSA-162582
Downregulation of ERBB2 signaling R-HSA-8863795
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Sema4D in semaphorin signaling R-HSA-400685
Drug resistance in ERBB2 KD mutants R-HSA-9665230
GRB2 events in ERBB2 signaling R-HSA-1963640
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Semaphorin interactions R-HSA-373755
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by ERBB2 in Cancer R-HSA-1227990
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Developmental Biology R-HSA-1266738
PLCG1 events in ERBB2 signaling R-HSA-1251932
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Gene expression (Transcription) R-HSA-74160
Signaling by ERBB2 ECD mutants R-HSA-9665348
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by ERBB2 R-HSA-1227986
Intracellular signaling by second messengers R-HSA-9006925
Axon guidance R-HSA-422475
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
RNA Polymerase II Transcription R-HSA-73857
PI3K/AKT Signaling in Cancer R-HSA-2219528
GRB7 events in ERBB2 signaling R-HSA-1306955
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SHC1 events in ERBB2 signaling R-HSA-1250196
Disease R-HSA-1643685
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by PTK6 R-HSA-8848021
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
MAPK family signaling cascades R-HSA-5683057
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by PTK6 R-HSA-8848021
ERBB2 Regulates Cell Motility R-HSA-6785631
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Developmental Biology R-HSA-1266738
RNA Polymerase II Transcription R-HSA-73857
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of the PI3K/AKT network R-HSA-199418
Disease R-HSA-1643685
Signaling by ERBB2 KD Mutants R-HSA-9664565
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Semaphorin interactions R-HSA-373755
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
Sema4D in semaphorin signaling R-HSA-400685
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
GRB7 events in ERBB2 signaling R-HSA-1306955
PI3K events in ERBB2 signaling R-HSA-1963642
PLCG1 events in ERBB2 signaling R-HSA-1251932
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by ERBB2 ECD mutants R-HSA-9665348
Downregulation of ERBB2 signaling R-HSA-8863795
Gene expression (Transcription) R-HSA-74160
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Generic Transcription Pathway R-HSA-212436
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Nervous system development R-HSA-9675108
Signaling by ERBB2 in Cancer R-HSA-1227990
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Signaling by ERBB2 R-HSA-1227986
SHC1 events in ERBB2 signaling R-HSA-1250196
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
ERBB2 Activates PTK6 Signaling R-HSA-8847993
GRB2 events in ERBB2 signaling R-HSA-1963640
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB2 KD Mutants R-HSA-9664565
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
Sema4D in semaphorin signaling R-HSA-400685
Axon guidance R-HSA-422475
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
SHC1 events in ERBB2 signaling R-HSA-1250196
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
GRB7 events in ERBB2 signaling R-HSA-1306955
ERBB2 Activates PTK6 Signaling R-HSA-8847993
PLCG1 events in ERBB2 signaling R-HSA-1251932
Downregulation of ERBB2 signaling R-HSA-8863795
Signaling by ERBB2 ECD mutants R-HSA-9665348
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Signaling by PTK6 R-HSA-8848021
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Developmental Biology R-HSA-1266738
Semaphorin interactions R-HSA-373755
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Intracellular signaling by second messengers R-HSA-9006925
PI3K/AKT Signaling in Cancer R-HSA-2219528
RAF/MAP kinase cascade R-HSA-5673001
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
MAPK1/MAPK3 signaling R-HSA-5684996
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
Signaling by ERBB2 R-HSA-1227986
Signaling by ERBB2 in Cancer R-HSA-1227990
PI3K events in ERBB2 signaling R-HSA-1963642
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Intracellular signaling by second messengers R-HSA-9006925
Gene expression (Transcription) R-HSA-74160
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Axon guidance R-HSA-422475
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by ERBB2 R-HSA-1227986
Sema4D in semaphorin signaling R-HSA-400685
Signaling by ERBB2 in Cancer R-HSA-1227990
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Semaphorin interactions R-HSA-373755
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Signaling by PTK6 R-HSA-8848021
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Signaling by ERBB2 KD Mutants R-HSA-9664565
GRB2 events in ERBB2 signaling R-HSA-1963640
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Generic Transcription Pathway R-HSA-212436
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
SHC1 events in ERBB2 signaling R-HSA-1250196
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by ERBB2 ECD mutants R-HSA-9665348
Disease R-HSA-1643685
Downregulation of ERBB2 signaling R-HSA-8863795
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K events in ERBB2 signaling R-HSA-1963642
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
ERBB2 Regulates Cell Motility R-HSA-6785631
GRB7 events in ERBB2 signaling R-HSA-1306955
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
PLCG1 events in ERBB2 signaling R-HSA-1251932
RNA Polymerase II Transcription R-HSA-73857
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
PI3K/AKT Signaling in Cancer R-HSA-2219528
RAF/MAP kinase cascade R-HSA-5673001
Semaphorin interactions R-HSA-373755
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
MAPK family signaling cascades R-HSA-5683057
PLCG1 events in ERBB2 signaling R-HSA-1251932
Axon guidance R-HSA-422475
GRB7 events in ERBB2 signaling R-HSA-1306955
RNA Polymerase II Transcription R-HSA-73857
GRB2 events in ERBB2 signaling R-HSA-1963640
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by ERBB2 in Cancer R-HSA-1227990
Generic Transcription Pathway R-HSA-212436
Signaling by ERBB2 R-HSA-1227986
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Disease R-HSA-1643685
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
ERBB2 Regulates Cell Motility R-HSA-6785631
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by ERBB2 ECD mutants R-HSA-9665348
Downregulation of ERBB2 signaling R-HSA-8863795
SHC1 events in ERBB2 signaling R-HSA-1250196
PIP3 activates AKT signaling R-HSA-1257604
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Sema4D in semaphorin signaling R-HSA-400685
Gene expression (Transcription) R-HSA-74160
Signaling by PTK6 R-HSA-8848021
Drug resistance in ERBB2 KD mutants R-HSA-9665230
PI3K events in ERBB2 signaling R-HSA-1963642
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Developmental Biology R-HSA-1266738
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Nervous system development R-HSA-9675108
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Signal Transduction R-HSA-162582
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
SHC1 events in ERBB2 signaling R-HSA-1250196
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
GRB7 events in ERBB2 signaling R-HSA-1306955
Intracellular signaling by second messengers R-HSA-9006925
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Developmental Biology R-HSA-1266738
Signaling by ERBB2 ECD mutants R-HSA-9665348
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Signaling by ERBB2 R-HSA-1227986
Sema4D in semaphorin signaling R-HSA-400685
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by ERBB2 KD Mutants R-HSA-9664565
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
ERBB2 Regulates Cell Motility R-HSA-6785631
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K events in ERBB2 signaling R-HSA-1963642
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Disease R-HSA-1643685
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
PLCG1 events in ERBB2 signaling R-HSA-1251932
Axon guidance R-HSA-422475
PIP3 activates AKT signaling R-HSA-1257604
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downregulation of ERBB2 signaling R-HSA-8863795
Semaphorin interactions R-HSA-373755
Signaling by PTK6 R-HSA-8848021
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
RAF/MAP kinase cascade R-HSA-5673001
RNA Polymerase II Transcription R-HSA-73857
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by PTK6 R-HSA-8848021
Drug resistance in ERBB2 KD mutants R-HSA-9665230
GRB7 events in ERBB2 signaling R-HSA-1306955
Downregulation of ERBB2 signaling R-HSA-8863795
PIP3 activates AKT signaling R-HSA-1257604
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
MAPK1/MAPK3 signaling R-HSA-5684996
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
RNA Polymerase II Transcription R-HSA-73857
Signaling by ERBB2 KD Mutants R-HSA-9664565
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K/AKT Signaling in Cancer R-HSA-2219528
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Negative regulation of the PI3K/AKT network R-HSA-199418
Developmental Biology R-HSA-1266738
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Semaphorin interactions R-HSA-373755
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
ERBB2 Activates PTK6 Signaling R-HSA-8847993
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
MAPK family signaling cascades R-HSA-5683057
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Intracellular signaling by second messengers R-HSA-9006925
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by ERBB2 in Cancer R-HSA-1227990
Sema4D in semaphorin signaling R-HSA-400685
Axon guidance R-HSA-422475
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Nervous system development R-HSA-9675108
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
SHC1 events in ERBB2 signaling R-HSA-1250196
RAF/MAP kinase cascade R-HSA-5673001
Generic Transcription Pathway R-HSA-212436
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
PLCG1 events in ERBB2 signaling R-HSA-1251932
Signaling by ERBB2 R-HSA-1227986
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Gene expression (Transcription) R-HSA-74160
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000141736
LRG display in Ensembl gene LRG_724
NCBI gene (formerly Entrezgene) 2064
GeneCards 3430
HGNC Symbol HGNC:3430
MIM gene 164870
MIM morbid 619465
UniProtKB Gene Name X5DNK3
WikiGene 2064
Gene: KIT
Ensembl ID : ENSG00000157404
Description: KIT proto-oncogene, receptor tyrosine kinase
Gene Synonyms: C-KIT,CD117,PBT,SCFR
32 APIs:
211 Possible Orthologues:

Signaling by extracellular domain mutants of KIT R-HSA-9680187
MAPK family signaling cascades R-HSA-5683057
PI3K/AKT Signaling in Cancer R-HSA-2219528
Generic Transcription Pathway R-HSA-212436
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Masitinib-resistant KIT mutants R-HSA-9669924
PIP3 activates AKT signaling R-HSA-1257604
Sorafenib-resistant KIT mutants R-HSA-9669936
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by kinase domain mutants of KIT R-HSA-9669933
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Drug resistance of KIT mutants R-HSA-9669937
Sunitinib-resistant KIT mutants R-HSA-9669934
Signaling by SCF-KIT R-HSA-1433557
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Disease R-HSA-1643685
KIT mutants bind TKIs R-HSA-9669921
RAF/MAP kinase cascade R-HSA-5673001
Dasatinib-resistant KIT mutants R-HSA-9669914
Intracellular signaling by second messengers R-HSA-9006925
Nilotinib-resistant KIT mutants R-HSA-9669926
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Regorafenib-resistant KIT mutants R-HSA-9669929
Regulation of KIT signaling R-HSA-1433559
Negative regulation of the PI3K/AKT network R-HSA-199418
Imatinib-resistant KIT mutants R-HSA-9669917
Signal Transduction R-HSA-162582
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by KIT in disease R-HSA-9669938
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
PI3K/AKT Signaling in Cancer R-HSA-2219528
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
MAPK family signaling cascades R-HSA-5683057
Drug resistance of KIT mutants R-HSA-9669937
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Sorafenib-resistant KIT mutants R-HSA-9669936
Intracellular signaling by second messengers R-HSA-9006925
Regulation of KIT signaling R-HSA-1433559
RNA Polymerase II Transcription R-HSA-73857
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of the PI3K/AKT network R-HSA-199418
Masitinib-resistant KIT mutants R-HSA-9669924
Signaling by SCF-KIT R-HSA-1433557
Signaling by kinase domain mutants of KIT R-HSA-9669933
Regorafenib-resistant KIT mutants R-HSA-9669929
Sunitinib-resistant KIT mutants R-HSA-9669934
Nilotinib-resistant KIT mutants R-HSA-9669926
Disease R-HSA-1643685
Signaling by KIT in disease R-HSA-9669938
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Imatinib-resistant KIT mutants R-HSA-9669917
MAPK1/MAPK3 signaling R-HSA-5684996
PIP3 activates AKT signaling R-HSA-1257604
Generic Transcription Pathway R-HSA-212436
KIT mutants bind TKIs R-HSA-9669921
Gene expression (Transcription) R-HSA-74160
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Dasatinib-resistant KIT mutants R-HSA-9669914
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Signal Transduction R-HSA-162582
Masitinib-resistant KIT mutants R-HSA-9669924
Generic Transcription Pathway R-HSA-212436
Signaling by kinase domain mutants of KIT R-HSA-9669933
PIP3 activates AKT signaling R-HSA-1257604
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Sorafenib-resistant KIT mutants R-HSA-9669936
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by KIT in disease R-HSA-9669938
Signal Transduction R-HSA-162582
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Nilotinib-resistant KIT mutants R-HSA-9669926
Intracellular signaling by second messengers R-HSA-9006925
Gene expression (Transcription) R-HSA-74160
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Dasatinib-resistant KIT mutants R-HSA-9669914
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Regulation of KIT signaling R-HSA-1433559
KIT mutants bind TKIs R-HSA-9669921
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regorafenib-resistant KIT mutants R-HSA-9669929
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Negative regulation of the PI3K/AKT network R-HSA-199418
Drug resistance of KIT mutants R-HSA-9669937
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Imatinib-resistant KIT mutants R-HSA-9669917
Signaling by SCF-KIT R-HSA-1433557
Sunitinib-resistant KIT mutants R-HSA-9669934
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Signaling by SCF-KIT R-HSA-1433557
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Regulation of KIT signaling R-HSA-1433559
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Sunitinib-resistant KIT mutants R-HSA-9669934
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Sorafenib-resistant KIT mutants R-HSA-9669936
MAPK1/MAPK3 signaling R-HSA-5684996
Masitinib-resistant KIT mutants R-HSA-9669924
Gene expression (Transcription) R-HSA-74160
RAF/MAP kinase cascade R-HSA-5673001
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
Dasatinib-resistant KIT mutants R-HSA-9669914
Regorafenib-resistant KIT mutants R-HSA-9669929
Imatinib-resistant KIT mutants R-HSA-9669917
KIT mutants bind TKIs R-HSA-9669921
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nilotinib-resistant KIT mutants R-HSA-9669926
RNA Polymerase II Transcription R-HSA-73857
Signaling by kinase domain mutants of KIT R-HSA-9669933
Drug resistance of KIT mutants R-HSA-9669937
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by KIT in disease R-HSA-9669938
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Drug resistance of KIT mutants R-HSA-9669937
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
KIT mutants bind TKIs R-HSA-9669921
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regorafenib-resistant KIT mutants R-HSA-9669929
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by extracellular domain mutants of KIT R-HSA-9680187
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by KIT in disease R-HSA-9669938
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Sunitinib-resistant KIT mutants R-HSA-9669934
Disease R-HSA-1643685
Nilotinib-resistant KIT mutants R-HSA-9669926
Signal Transduction R-HSA-162582
Sorafenib-resistant KIT mutants R-HSA-9669936
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by SCF-KIT R-HSA-1433557
Regulation of KIT signaling R-HSA-1433559
PIP3 activates AKT signaling R-HSA-1257604
Generic Transcription Pathway R-HSA-212436
RAF/MAP kinase cascade R-HSA-5673001
Imatinib-resistant KIT mutants R-HSA-9669917
Masitinib-resistant KIT mutants R-HSA-9669924
MAPK family signaling cascades R-HSA-5683057
PI3K/AKT Signaling in Cancer R-HSA-2219528
Dasatinib-resistant KIT mutants R-HSA-9669914
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by kinase domain mutants of KIT R-HSA-9669933
Drug resistance of KIT mutants R-HSA-9669937
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Generic Transcription Pathway R-HSA-212436
KIT mutants bind TKIs R-HSA-9669921
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K/AKT Signaling in Cancer R-HSA-2219528
Masitinib-resistant KIT mutants R-HSA-9669924
Nilotinib-resistant KIT mutants R-HSA-9669926
Regulation of KIT signaling R-HSA-1433559
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Imatinib-resistant KIT mutants R-HSA-9669917
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Sorafenib-resistant KIT mutants R-HSA-9669936
Signaling by kinase domain mutants of KIT R-HSA-9669933
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by SCF-KIT R-HSA-1433557
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
Sunitinib-resistant KIT mutants R-HSA-9669934
Regorafenib-resistant KIT mutants R-HSA-9669929
Negative regulation of the PI3K/AKT network R-HSA-199418
Gene expression (Transcription) R-HSA-74160
Dasatinib-resistant KIT mutants R-HSA-9669914
Signaling by KIT in disease R-HSA-9669938
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signal Transduction R-HSA-162582
Imatinib-resistant KIT mutants R-HSA-9669917
Nilotinib-resistant KIT mutants R-HSA-9669926
Signaling by KIT in disease R-HSA-9669938
Sorafenib-resistant KIT mutants R-HSA-9669936
RNA Polymerase II Transcription R-HSA-73857
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
MAPK1/MAPK3 signaling R-HSA-5684996
Gene expression (Transcription) R-HSA-74160
Dasatinib-resistant KIT mutants R-HSA-9669914
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Regorafenib-resistant KIT mutants R-HSA-9669929
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
KIT mutants bind TKIs R-HSA-9669921
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by kinase domain mutants of KIT R-HSA-9669933
Masitinib-resistant KIT mutants R-HSA-9669924
MAPK family signaling cascades R-HSA-5683057
Drug resistance of KIT mutants R-HSA-9669937
Generic Transcription Pathway R-HSA-212436
Sunitinib-resistant KIT mutants R-HSA-9669934
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by SCF-KIT R-HSA-1433557
Regulation of KIT signaling R-HSA-1433559
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Intracellular signaling by second messengers R-HSA-9006925
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Signaling by SCF-KIT R-HSA-1433557
Sorafenib-resistant KIT mutants R-HSA-9669936
MAPK1/MAPK3 signaling R-HSA-5684996
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
RAF/MAP kinase cascade R-HSA-5673001
Regulation of KIT signaling R-HSA-1433559
PIP3 activates AKT signaling R-HSA-1257604
Nilotinib-resistant KIT mutants R-HSA-9669926
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by kinase domain mutants of KIT R-HSA-9669933
Signaling by KIT in disease R-HSA-9669938
Disease R-HSA-1643685
Dasatinib-resistant KIT mutants R-HSA-9669914
Masitinib-resistant KIT mutants R-HSA-9669924
Imatinib-resistant KIT mutants R-HSA-9669917
Sunitinib-resistant KIT mutants R-HSA-9669934
Signaling by extracellular domain mutants of KIT R-HSA-9680187
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Drug resistance of KIT mutants R-HSA-9669937
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Regorafenib-resistant KIT mutants R-HSA-9669929
Negative regulation of the PI3K/AKT network R-HSA-199418
KIT mutants bind TKIs R-HSA-9669921
Gene expression (Transcription) R-HSA-74160
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Regulation of KIT signaling R-HSA-1433559
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
KIT mutants bind TKIs R-HSA-9669921
Sorafenib-resistant KIT mutants R-HSA-9669936
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by kinase domain mutants of KIT R-HSA-9669933
Nilotinib-resistant KIT mutants R-HSA-9669926
Regorafenib-resistant KIT mutants R-HSA-9669929
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RNA Polymerase II Transcription R-HSA-73857
Signaling by SCF-KIT R-HSA-1433557
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Masitinib-resistant KIT mutants R-HSA-9669924
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by KIT in disease R-HSA-9669938
Dasatinib-resistant KIT mutants R-HSA-9669914
Imatinib-resistant KIT mutants R-HSA-9669917
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
PI3K/AKT Signaling in Cancer R-HSA-2219528
Drug resistance of KIT mutants R-HSA-9669937
Sunitinib-resistant KIT mutants R-HSA-9669934
Disease R-HSA-1643685
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of the PI3K/AKT network R-HSA-199418
Masitinib-resistant KIT mutants R-HSA-9669924
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935
Nilotinib-resistant KIT mutants R-HSA-9669926
Signaling by extracellular domain mutants of KIT R-HSA-9680187
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Imatinib-resistant KIT mutants R-HSA-9669917
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Drug resistance of KIT mutants R-HSA-9669937
Signaling by SCF-KIT R-HSA-1433557
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by KIT in disease R-HSA-9669938
Dasatinib-resistant KIT mutants R-HSA-9669914
Signaling by kinase domain mutants of KIT R-HSA-9669933
PI3K/AKT Signaling in Cancer R-HSA-2219528
Disease R-HSA-1643685
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Regulation of KIT signaling R-HSA-1433559
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Sunitinib-resistant KIT mutants R-HSA-9669934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Regorafenib-resistant KIT mutants R-HSA-9669929
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
Sorafenib-resistant KIT mutants R-HSA-9669936
Negative regulation of the PI3K/AKT network R-HSA-199418
KIT mutants bind TKIs R-HSA-9669921
Signaling by Receptor Tyrosine Kinases R-HSA-9006934

Expression Atlas ENSG00000157404
LRG display in Ensembl gene LRG_307
NCBI gene (formerly Entrezgene) 3815
GeneCards 6342
HGNC Symbol HGNC:6342
MIM gene 164920
MIM morbid 606764
UniProtKB Gene Name P10721
WikiGene 3815
Gene: EPHA2
Ensembl ID : ENSG00000142627
Description: EPH receptor A2
Gene Synonyms: ECK
2 APIs:
124 Possible Orthologues:

Signal Transduction R-HSA-162582
RAC1 GTPase cycle R-HSA-9013149
Developmental Biology R-HSA-1266738
RHO GTPase cycle R-HSA-9012999
RHOV GTPase cycle R-HSA-9013424
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHOU GTPase cycle R-HSA-9013420
RND2 GTPase cycle R-HSA-9696270
RND3 GTPase cycle R-HSA-9696264
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Signaling by Rho GTPases R-HSA-194315
RHOG GTPase cycle R-HSA-9013408
RAC3 GTPase cycle R-HSA-9013423
EPH-Ephrin signaling R-HSA-2682334
EPH-ephrin mediated repulsion of cells R-HSA-3928665
RAC2 GTPase cycle R-HSA-9013404
RND1 GTPase cycle R-HSA-9696273
EPHA-mediated growth cone collapse R-HSA-3928663
RHOU GTPase cycle R-HSA-9013420
Signaling by Rho GTPases R-HSA-194315
RND2 GTPase cycle R-HSA-9696270
RAC2 GTPase cycle R-HSA-9013404
Nervous system development R-HSA-9675108
EPH-Ephrin signaling R-HSA-2682334
RHOG GTPase cycle R-HSA-9013408
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
EPH-ephrin mediated repulsion of cells R-HSA-3928665
EPHA-mediated growth cone collapse R-HSA-3928663
Axon guidance R-HSA-422475
RAC1 GTPase cycle R-HSA-9013149
RHOV GTPase cycle R-HSA-9013424
RND1 GTPase cycle R-HSA-9696273
RHO GTPase cycle R-HSA-9012999
RAC3 GTPase cycle R-HSA-9013423
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
RND3 GTPase cycle R-HSA-9696264
RHOV GTPase cycle R-HSA-9013424
Signal Transduction R-HSA-162582
RAC1 GTPase cycle R-HSA-9013149
EPH-Ephrin signaling R-HSA-2682334
EPH-ephrin mediated repulsion of cells R-HSA-3928665
RAC2 GTPase cycle R-HSA-9013404
RND3 GTPase cycle R-HSA-9696264
Nervous system development R-HSA-9675108
RAC3 GTPase cycle R-HSA-9013423
RHO GTPase cycle R-HSA-9012999
Signaling by Rho GTPases R-HSA-194315
RHOU GTPase cycle R-HSA-9013420
Axon guidance R-HSA-422475
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RND2 GTPase cycle R-HSA-9696270
Developmental Biology R-HSA-1266738
RHOG GTPase cycle R-HSA-9013408
RND1 GTPase cycle R-HSA-9696273
EPHA-mediated growth cone collapse R-HSA-3928663
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Rho GTPases R-HSA-194315
RHOV GTPase cycle R-HSA-9013424
RHOU GTPase cycle R-HSA-9013420
EPHA-mediated growth cone collapse R-HSA-3928663
RND2 GTPase cycle R-HSA-9696270
Axon guidance R-HSA-422475
RAC3 GTPase cycle R-HSA-9013423
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHOG GTPase cycle R-HSA-9013408
RND3 GTPase cycle R-HSA-9696264
RHO GTPase cycle R-HSA-9012999
RAC2 GTPase cycle R-HSA-9013404
RND1 GTPase cycle R-HSA-9696273
EPH-Ephrin signaling R-HSA-2682334
RAC1 GTPase cycle R-HSA-9013149
EPH-ephrin mediated repulsion of cells R-HSA-3928665
RND1 GTPase cycle R-HSA-9696273
Developmental Biology R-HSA-1266738
RHOG GTPase cycle R-HSA-9013408
Signaling by Rho GTPases R-HSA-194315
EPH-Ephrin signaling R-HSA-2682334
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
RAC1 GTPase cycle R-HSA-9013149
RAC2 GTPase cycle R-HSA-9013404
RHOV GTPase cycle R-HSA-9013424
RND3 GTPase cycle R-HSA-9696264
EPHA-mediated growth cone collapse R-HSA-3928663
Nervous system development R-HSA-9675108
RAC3 GTPase cycle R-HSA-9013423
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RND2 GTPase cycle R-HSA-9696270
RHOU GTPase cycle R-HSA-9013420
RHO GTPase cycle R-HSA-9012999
RAC1 GTPase cycle R-HSA-9013149
RHOU GTPase cycle R-HSA-9013420
EPH-ephrin mediated repulsion of cells R-HSA-3928665
RND1 GTPase cycle R-HSA-9696273
Axon guidance R-HSA-422475
RND3 GTPase cycle R-HSA-9696264
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
EPH-Ephrin signaling R-HSA-2682334
RAC3 GTPase cycle R-HSA-9013423
EPHA-mediated growth cone collapse R-HSA-3928663
Nervous system development R-HSA-9675108
RHOG GTPase cycle R-HSA-9013408
RAC2 GTPase cycle R-HSA-9013404
Signaling by Rho GTPases R-HSA-194315
RND2 GTPase cycle R-HSA-9696270
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
RHO GTPase cycle R-HSA-9012999
RHOV GTPase cycle R-HSA-9013424
RAC2 GTPase cycle R-HSA-9013404
Nervous system development R-HSA-9675108
RND3 GTPase cycle R-HSA-9696264
RHO GTPase cycle R-HSA-9012999
Signal Transduction R-HSA-162582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RAC3 GTPase cycle R-HSA-9013423
RHOG GTPase cycle R-HSA-9013408
EPH-Ephrin signaling R-HSA-2682334
RND2 GTPase cycle R-HSA-9696270
RHOV GTPase cycle R-HSA-9013424
RAC1 GTPase cycle R-HSA-9013149
EPHA-mediated growth cone collapse R-HSA-3928663
RND1 GTPase cycle R-HSA-9696273
RHOU GTPase cycle R-HSA-9013420
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Rho GTPases R-HSA-194315
Axon guidance R-HSA-422475
RHOU GTPase cycle R-HSA-9013420
Signaling by Rho GTPases R-HSA-194315
RHOV GTPase cycle R-HSA-9013424
RND2 GTPase cycle R-HSA-9696270
RAC1 GTPase cycle R-HSA-9013149
Developmental Biology R-HSA-1266738
EPHA-mediated growth cone collapse R-HSA-3928663
EPH-Ephrin signaling R-HSA-2682334
RHOG GTPase cycle R-HSA-9013408
RAC3 GTPase cycle R-HSA-9013423
Signal Transduction R-HSA-162582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RAC2 GTPase cycle R-HSA-9013404
RHO GTPase cycle R-HSA-9012999
Nervous system development R-HSA-9675108
RND3 GTPase cycle R-HSA-9696264
RND1 GTPase cycle R-HSA-9696273
EPH-ephrin mediated repulsion of cells R-HSA-3928665
RHO GTPase cycle R-HSA-9012999
RHOV GTPase cycle R-HSA-9013424
RND2 GTPase cycle R-HSA-9696270
Signal Transduction R-HSA-162582
RND1 GTPase cycle R-HSA-9696273
RAC2 GTPase cycle R-HSA-9013404
RHOG GTPase cycle R-HSA-9013408
EPHA-mediated growth cone collapse R-HSA-3928663
RHOU GTPase cycle R-HSA-9013420
RAC1 GTPase cycle R-HSA-9013149
Signaling by Rho GTPases R-HSA-194315
Nervous system development R-HSA-9675108
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Axon guidance R-HSA-422475
RND3 GTPase cycle R-HSA-9696264
EPH-Ephrin signaling R-HSA-2682334
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Developmental Biology R-HSA-1266738
RAC3 GTPase cycle R-HSA-9013423

Expression Atlas ENSG00000142627
NCBI gene (formerly Entrezgene) 1969
GeneCards 3386
HGNC Symbol HGNC:3386
MIM gene 176946
MIM morbid 116600
UniProtKB Gene Name P29317
WikiGene 1969
Gene: NTRK3
Ensembl ID : ENSG00000140538
Description: neurotrophic receptor tyrosine kinase 3
Gene Synonyms: TRKC
3 APIs:
271 Possible Orthologues:

Signaling by NTRKs R-HSA-166520
NTRK3 as a dependence receptor R-HSA-9603505
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through PI3K R-HSA-9603381
Neuronal System R-HSA-112316
Protein-protein interactions at synapses R-HSA-6794362
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTF3 activates NTRK3 signaling R-HSA-9034013
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Activated NTRK3 signals through RAS R-HSA-9034864
Signal Transduction R-HSA-162582
Activated NTRK3 signals through PI3K R-HSA-9603381
Activated NTRK3 signals through RAS R-HSA-9034864
Activated NTRK3 signals through PLCG1 R-HSA-9034793
NTRK3 as a dependence receptor R-HSA-9603505
Signal Transduction R-HSA-162582
Protein-protein interactions at synapses R-HSA-6794362
Signaling by NTRK3 (TRKC) R-HSA-9034015
NTF3 activates NTRK3 signaling R-HSA-9034013
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRKs R-HSA-166520
Neuronal System R-HSA-112316
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Signal Transduction R-HSA-162582
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by NTRKs R-HSA-166520
Activated NTRK3 signals through RAS R-HSA-9034864
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRK3 (TRKC) R-HSA-9034015
NTF3 activates NTRK3 signaling R-HSA-9034013
NTRK3 as a dependence receptor R-HSA-9603505
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Protein-protein interactions at synapses R-HSA-6794362
Neuronal System R-HSA-112316
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTF3 activates NTRK3 signaling R-HSA-9034013
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through RAS R-HSA-9034864
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Protein-protein interactions at synapses R-HSA-6794362
Signal Transduction R-HSA-162582
NTRK3 as a dependence receptor R-HSA-9603505
Neuronal System R-HSA-112316
Signaling by NTRKs R-HSA-166520
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Activated NTRK3 signals through PI3K R-HSA-9603381
Protein-protein interactions at synapses R-HSA-6794362
NTF3 activates NTRK3 signaling R-HSA-9034013
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activated NTRK3 signals through RAS R-HSA-9034864
Signaling by NTRKs R-HSA-166520
Signaling by NTRK3 (TRKC) R-HSA-9034015
NTRK3 as a dependence receptor R-HSA-9603505
Activated NTRK3 signals through PI3K R-HSA-9603381
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Signal Transduction R-HSA-162582
Neuronal System R-HSA-112316
Signaling by NTRKs R-HSA-166520
NTRK3 as a dependence receptor R-HSA-9603505
Signaling by NTRK3 (TRKC) R-HSA-9034015
Receptor-type tyrosine-protein phosphatases R-HSA-388844
NTF3 activates NTRK3 signaling R-HSA-9034013
Signal Transduction R-HSA-162582
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Protein-protein interactions at synapses R-HSA-6794362
Activated NTRK3 signals through RAS R-HSA-9034864
Neuronal System R-HSA-112316
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Protein-protein interactions at synapses R-HSA-6794362
Signaling by NTRKs R-HSA-166520
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTRK3 as a dependence receptor R-HSA-9603505
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through PI3K R-HSA-9603381
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Activated NTRK3 signals through RAS R-HSA-9034864
NTF3 activates NTRK3 signaling R-HSA-9034013
Signal Transduction R-HSA-162582
Neuronal System R-HSA-112316
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Neuronal System R-HSA-112316
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activated NTRK3 signals through RAS R-HSA-9034864
NTRK3 as a dependence receptor R-HSA-9603505
NTF3 activates NTRK3 signaling R-HSA-9034013
Signal Transduction R-HSA-162582
Protein-protein interactions at synapses R-HSA-6794362
Signaling by NTRKs R-HSA-166520
Signaling by NTRKs R-HSA-166520
Activated NTRK3 signals through PLCG1 R-HSA-9034793
Neuronal System R-HSA-112316
Signaling by NTRK3 (TRKC) R-HSA-9034015
Activated NTRK3 signals through RAS R-HSA-9034864
Protein-protein interactions at synapses R-HSA-6794362
Signal Transduction R-HSA-162582
NTRK3 as a dependence receptor R-HSA-9603505
Activated NTRK3 signals through PI3K R-HSA-9603381
Receptor-type tyrosine-protein phosphatases R-HSA-388844
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NTF3 activates NTRK3 signaling R-HSA-9034013

Expression Atlas ENSG00000140538
NCBI gene (formerly Entrezgene) 4916
GeneCards 8033
HGNC Symbol HGNC:8033
MIM gene 191316
UniProtKB Gene Name X5DNW6
WikiGene 4916
Gene: PRKCB
Ensembl ID : ENSG00000166501
Description: protein kinase C beta
Gene Synonyms: PKCB,PRKCB1,PRKCB2
7 APIs:
299 Possible Orthologues:

Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Neuronal System R-HSA-112316
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle R-HSA-1640170
Trafficking of AMPA receptors R-HSA-399719
Signaling by VEGF R-HSA-194138
WNT5A-dependent internalization of FZD4 R-HSA-5099900
G alpha (z) signalling events R-HSA-418597
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Immune System R-HSA-168256
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
VEGFR2 mediated cell proliferation R-HSA-5218921
Adaptive Immune System R-HSA-1280218
Disinhibition of SNARE formation R-HSA-114516
Signaling by GPCR R-HSA-372790
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Beta-catenin independent WNT signaling R-HSA-3858494
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Hemostasis R-HSA-109582
Nuclear Envelope Breakdown R-HSA-2980766
Gene expression (Transcription) R-HSA-74160
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
GPCR downstream signalling R-HSA-388396
Signaling by WNT R-HSA-195721
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Mitotic Prophase R-HSA-68875
RHO GTPase Effectors R-HSA-195258
Platelet activation, signaling and aggregation R-HSA-76002
PCP/CE pathway R-HSA-4086400
Transmission across Chemical Synapses R-HSA-112315
RNA Polymerase II Transcription R-HSA-73857
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
VEGFA-VEGFR2 Pathway R-HSA-4420097
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle, Mitotic R-HSA-69278
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Transmission across Chemical Synapses R-HSA-112315
Beta-catenin independent WNT signaling R-HSA-3858494
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
G alpha (z) signalling events R-HSA-418597
VEGFR2 mediated cell proliferation R-HSA-5218921
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
VEGFA-VEGFR2 Pathway R-HSA-4420097
Trafficking of AMPA receptors R-HSA-399719
Neuronal System R-HSA-112316
Cell Cycle R-HSA-1640170
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
Disinhibition of SNARE formation R-HSA-114516
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transcriptional regulation by RUNX1 R-HSA-8878171
Nuclear Envelope Breakdown R-HSA-2980766
M Phase R-HSA-68886
Immune System R-HSA-168256
Hemostasis R-HSA-109582
Signaling by GPCR R-HSA-372790
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by WNT R-HSA-195721
Cell Cycle, Mitotic R-HSA-69278
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Generic Transcription Pathway R-HSA-212436
Mitotic Prophase R-HSA-68875
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RNA Polymerase II Transcription R-HSA-73857
Depolymerisation of the Nuclear Lamina R-HSA-4419969
PCP/CE pathway R-HSA-4086400
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
GPCR downstream signalling R-HSA-388396
Signaling by VEGF R-HSA-194138
Activation of NF-kappaB in B cells R-HSA-1169091
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by Rho GTPases R-HSA-194315
Adaptive Immune System R-HSA-1280218
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
RHO GTPase Effectors R-HSA-195258
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
G alpha (z) signalling events R-HSA-418597
GPCR downstream signalling R-HSA-388396
Nuclear Envelope Breakdown R-HSA-2980766
Platelet activation, signaling and aggregation R-HSA-76002
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Trafficking of AMPA receptors R-HSA-399719
Signaling by Rho GTPases R-HSA-194315
Cell Cycle, Mitotic R-HSA-69278
RHO GTPase Effectors R-HSA-195258
Hemostasis R-HSA-109582
Cell Cycle R-HSA-1640170
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
VEGFA-VEGFR2 Pathway R-HSA-4420097
M Phase R-HSA-68886
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
Signaling by GPCR R-HSA-372790
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Signaling by WNT R-HSA-195721
Signaling by VEGF R-HSA-194138
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Adaptive Immune System R-HSA-1280218
Beta-catenin independent WNT signaling R-HSA-3858494
VEGFR2 mediated cell proliferation R-HSA-5218921
Mitotic Prophase R-HSA-68875
RNA Polymerase II Transcription R-HSA-73857
Disinhibition of SNARE formation R-HSA-114516
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
PCP/CE pathway R-HSA-4086400
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Adaptive Immune System R-HSA-1280218
M Phase R-HSA-68886
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases R-HSA-194315
Signaling by VEGF R-HSA-194138
Immune System R-HSA-168256
Nuclear Envelope Breakdown R-HSA-2980766
G alpha (z) signalling events R-HSA-418597
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Neuronal System R-HSA-112316
Generic Transcription Pathway R-HSA-212436
WNT5A-dependent internalization of FZD4 R-HSA-5099900
VEGFA-VEGFR2 Pathway R-HSA-4420097
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by GPCR R-HSA-372790
Cell Cycle R-HSA-1640170
Mitotic Prophase R-HSA-68875
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
GPCR downstream signalling R-HSA-388396
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cell Cycle, Mitotic R-HSA-69278
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Platelet activation, signaling and aggregation R-HSA-76002
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Gene expression (Transcription) R-HSA-74160
Trafficking of AMPA receptors R-HSA-399719
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
Activation of NF-kappaB in B cells R-HSA-1169091
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Hemostasis R-HSA-109582
Beta-catenin independent WNT signaling R-HSA-3858494
Transmission across Chemical Synapses R-HSA-112315
RNA Polymerase II Transcription R-HSA-73857
RHO GTPase Effectors R-HSA-195258
PCP/CE pathway R-HSA-4086400
VEGFR2 mediated cell proliferation R-HSA-5218921
Disinhibition of SNARE formation R-HSA-114516
Depolymerisation of the Nuclear Lamina R-HSA-4419969
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Mitotic Prophase R-HSA-68875
Trafficking of AMPA receptors R-HSA-399719
Disinhibition of SNARE formation R-HSA-114516
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Signaling by Rho GTPases R-HSA-194315
Adaptive Immune System R-HSA-1280218
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Transmission across Chemical Synapses R-HSA-112315
Cell Cycle, Mitotic R-HSA-69278
Activation of NF-kappaB in B cells R-HSA-1169091
RHO GTPase Effectors R-HSA-195258
Cell Cycle R-HSA-1640170
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Transcriptional regulation by RUNX1 R-HSA-8878171
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
Neuronal System R-HSA-112316
Beta-catenin independent WNT signaling R-HSA-3858494
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Gene expression (Transcription) R-HSA-74160
VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by VEGF R-HSA-194138
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
PCP/CE pathway R-HSA-4086400
G alpha (z) signalling events R-HSA-418597
Signaling by WNT R-HSA-195721
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
GPCR downstream signalling R-HSA-388396
RNA Polymerase II Transcription R-HSA-73857
Immune System R-HSA-168256
Hemostasis R-HSA-109582
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
M Phase R-HSA-68886
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by GPCR R-HSA-372790
Nuclear Envelope Breakdown R-HSA-2980766
Platelet activation, signaling and aggregation R-HSA-76002
Disinhibition of SNARE formation R-HSA-114516
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Trafficking of AMPA receptors R-HSA-399719
Generic Transcription Pathway R-HSA-212436
WNT5A-dependent internalization of FZD4 R-HSA-5099900
RNA Polymerase II Transcription R-HSA-73857
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by the B Cell Receptor (BCR) R-HSA-983705
VEGFR2 mediated cell proliferation R-HSA-5218921
Transmission across Chemical Synapses R-HSA-112315
G alpha (z) signalling events R-HSA-418597
Gene expression (Transcription) R-HSA-74160
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Cell Cycle R-HSA-1640170
PCP/CE pathway R-HSA-4086400
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Immune System R-HSA-168256
Cell Cycle, Mitotic R-HSA-69278
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Mitotic Prophase R-HSA-68875
Signaling by Rho GTPases R-HSA-194315
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
M Phase R-HSA-68886
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Hemostasis R-HSA-109582
Neuronal System R-HSA-112316
Beta-catenin independent WNT signaling R-HSA-3858494
Nuclear Envelope Breakdown R-HSA-2980766
RHO GTPase Effectors R-HSA-195258
Signaling by WNT R-HSA-195721
Signaling by VEGF R-HSA-194138
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX1 R-HSA-8878171
GPCR downstream signalling R-HSA-388396
Adaptive Immune System R-HSA-1280218
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Nuclear Envelope Breakdown R-HSA-2980766
Mitotic Prophase R-HSA-68875
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by WNT R-HSA-195721
VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by VEGF R-HSA-194138
Platelet activation, signaling and aggregation R-HSA-76002
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Beta-catenin independent WNT signaling R-HSA-3858494
GPCR downstream signalling R-HSA-388396
Trafficking of AMPA receptors R-HSA-399719
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by Rho GTPases R-HSA-194315
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Neuronal System R-HSA-112316
Signaling by GPCR R-HSA-372790
PCP/CE pathway R-HSA-4086400
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
M Phase R-HSA-68886
Generic Transcription Pathway R-HSA-212436
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
G alpha (z) signalling events R-HSA-418597
WNT5A-dependent internalization of FZD4 R-HSA-5099900
VEGFA-VEGFR2 Pathway R-HSA-4420097
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Immune System R-HSA-168256
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transmission across Chemical Synapses R-HSA-112315
Hemostasis R-HSA-109582
RHO GTPase Effectors R-HSA-195258
Depolymerisation of the Nuclear Lamina R-HSA-4419969
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
Cell Cycle R-HSA-1640170
Disinhibition of SNARE formation R-HSA-114516
Cell Cycle, Mitotic R-HSA-69278
RNA Polymerase II Transcription R-HSA-73857
M Phase R-HSA-68886
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Cell Cycle, Mitotic R-HSA-69278
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RNA Polymerase II Transcription R-HSA-73857
GPCR downstream signalling R-HSA-388396
Platelet activation, signaling and aggregation R-HSA-76002
Immune System R-HSA-168256
Cell Cycle R-HSA-1640170
Signaling by Rho GTPases R-HSA-194315
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Neuronal System R-HSA-112316
Signaling by VEGF R-HSA-194138
RHO GTPase Effectors R-HSA-195258
Generic Transcription Pathway R-HSA-212436
Hemostasis R-HSA-109582
Signaling by WNT R-HSA-195721
Nuclear Envelope Breakdown R-HSA-2980766
VEGFR2 mediated cell proliferation R-HSA-5218921
G alpha (z) signalling events R-HSA-418597
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signal Transduction R-HSA-162582
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transmission across Chemical Synapses R-HSA-112315
Disinhibition of SNARE formation R-HSA-114516
Activation of NF-kappaB in B cells R-HSA-1169091
PCP/CE pathway R-HSA-4086400
Signaling by GPCR R-HSA-372790
Mitotic Prophase R-HSA-68875
VEGFA-VEGFR2 Pathway R-HSA-4420097
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
Beta-catenin independent WNT signaling R-HSA-3858494
Trafficking of AMPA receptors R-HSA-399719
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Signaling by GPCR R-HSA-372790
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transcriptional regulation by RUNX1 R-HSA-8878171
Trafficking of AMPA receptors R-HSA-399719
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Nuclear Envelope Breakdown R-HSA-2980766
Disinhibition of SNARE formation R-HSA-114516
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Transmission across Chemical Synapses R-HSA-112315
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Immune System R-HSA-168256
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Platelet activation, signaling and aggregation R-HSA-76002
Adaptive Immune System R-HSA-1280218
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
Gene expression (Transcription) R-HSA-74160
GPCR downstream signalling R-HSA-388396
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
M Phase R-HSA-68886
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle, Mitotic R-HSA-69278
PCP/CE pathway R-HSA-4086400
Signaling by Rho GTPases R-HSA-194315
RHO GTPase Effectors R-HSA-195258
Signal Transduction R-HSA-162582
Beta-catenin independent WNT signaling R-HSA-3858494
RNA Polymerase II Transcription R-HSA-73857
Neuronal System R-HSA-112316
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Signaling by WNT R-HSA-195721
Cell Cycle R-HSA-1640170
Signaling by VEGF R-HSA-194138
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Hemostasis R-HSA-109582
Mitotic Prophase R-HSA-68875
Activation of NF-kappaB in B cells R-HSA-1169091
Generic Transcription Pathway R-HSA-212436
G alpha (z) signalling events R-HSA-418597
VEGFR2 mediated cell proliferation R-HSA-5218921
Trafficking of GluR2-containing AMPA receptors R-HSA-416993
Cell Cycle R-HSA-1640170
Disinhibition of SNARE formation R-HSA-114516
Neuronal System R-HSA-112316
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
M Phase R-HSA-68886
RHO GTPase Effectors R-HSA-195258
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Activation of NF-kappaB in B cells R-HSA-1169091
Adaptive Immune System R-HSA-1280218
Cell Cycle, Mitotic R-HSA-69278
Signaling by WNT R-HSA-195721
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246
G alpha (z) signalling events R-HSA-418597
VEGFR2 mediated cell proliferation R-HSA-5218921
Transcriptional regulation by RUNX1 R-HSA-8878171
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by Rho GTPases R-HSA-194315
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Signaling by VEGF R-HSA-194138
WNT5A-dependent internalization of FZD4 R-HSA-5099900
Transmission across Chemical Synapses R-HSA-112315
Signal Transduction R-HSA-162582
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by GPCR R-HSA-372790
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Nuclear Envelope Breakdown R-HSA-2980766
Immune System R-HSA-168256
Gene expression (Transcription) R-HSA-74160
Hemostasis R-HSA-109582
Mitotic Prophase R-HSA-68875
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
GPCR downstream signalling R-HSA-388396
VEGFA-VEGFR2 Pathway R-HSA-4420097
RNA Polymerase II Transcription R-HSA-73857
Platelet activation, signaling and aggregation R-HSA-76002
Trafficking of AMPA receptors R-HSA-399719
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Generic Transcription Pathway R-HSA-212436

Expression Atlas ENSG00000166501
NCBI gene (formerly Entrezgene) 5579
GeneCards 9395
HGNC Symbol HGNC:9395
MIM gene 176970
UniProtKB Gene Name P05771
WikiGene 5579
Gene: CDK5
Ensembl ID : ENSG00000164885
Description: cyclin dependent kinase 5
Gene Synonyms: PSSALRE
3 APIs:
166 Possible Orthologues:

Signaling by NTRKs R-HSA-166520
CRMPs in Sema3A signaling R-HSA-399956
Diseases of programmed cell death R-HSA-9645723
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity R-HSA-5633007
Signal Transduction R-HSA-162582
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by GPCR R-HSA-372790
Activated NTRK2 signals through CDK5 R-HSA-9032845
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Transcriptional Regulation by NPAS4 R-HSA-9634815
Generic Transcription Pathway R-HSA-212436
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRK2 (TRKB) R-HSA-9006115
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Signaling by NTRKs R-HSA-166520
Nervous system development R-HSA-9675108
G alpha (i) signalling events R-HSA-418594
DARPP-32 events R-HSA-180024
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Neurodegenerative Diseases R-HSA-8863678
Signaling by NTRK1 (TRKA) R-HSA-187037
CRMPs in Sema3A signaling R-HSA-399956
GPCR downstream signalling R-HSA-388396
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Hemostasis R-HSA-109582
Opioid Signalling R-HSA-111885
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
NGF-stimulated transcription R-HSA-9031628
Transcriptional Regulation by TP53 R-HSA-3700989
Semaphorin interactions R-HSA-373755
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
G alpha (i) signalling events R-HSA-418594
Gene expression (Transcription) R-HSA-74160
Signaling by NTRK1 (TRKA) R-HSA-187037
Opioid Signalling R-HSA-111885
Regulation of TP53 Activity R-HSA-5633007
Hemostasis R-HSA-109582
NGF-stimulated transcription R-HSA-9031628
Diseases of programmed cell death R-HSA-9645723
Nervous system development R-HSA-9675108
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signal Transduction R-HSA-162582
Transcriptional Regulation by TP53 R-HSA-3700989
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
CRMPs in Sema3A signaling R-HSA-399956
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
RNA Polymerase II Transcription R-HSA-73857
Activated NTRK2 signals through CDK5 R-HSA-9032845
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
GPCR downstream signalling R-HSA-388396
DARPP-32 events R-HSA-180024
Transcriptional Regulation by NPAS4 R-HSA-9634815
Semaphorin interactions R-HSA-373755
Disease R-HSA-1643685
Neurodegenerative Diseases R-HSA-8863678
Axon guidance R-HSA-422475
Signaling by NTRK2 (TRKB) R-HSA-9006115
NPAS4 regulates expression of target genes R-HSA-9768919
Developmental Biology R-HSA-1266738
Signaling by GPCR R-HSA-372790
Signaling by NTRKs R-HSA-166520
Generic Transcription Pathway R-HSA-212436
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRK2 (TRKB) R-HSA-9006115
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by TP53 R-HSA-3700989
Nervous system development R-HSA-9675108
Signaling by GPCR R-HSA-372790
DARPP-32 events R-HSA-180024
Opioid Signalling R-HSA-111885
Generic Transcription Pathway R-HSA-212436
NPAS4 regulates expression of target genes R-HSA-9768919
Diseases of programmed cell death R-HSA-9645723
G alpha (i) signalling events R-HSA-418594
Developmental Biology R-HSA-1266738
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
RNA Polymerase II Transcription R-HSA-73857
Signaling by NTRK1 (TRKA) R-HSA-187037
Axon guidance R-HSA-422475
Disease R-HSA-1643685
CRMPs in Sema3A signaling R-HSA-399956
Signal Transduction R-HSA-162582
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by NTRKs R-HSA-166520
Hemostasis R-HSA-109582
NGF-stimulated transcription R-HSA-9031628
Factors involved in megakaryocyte development and platelet production R-HSA-983231
GPCR downstream signalling R-HSA-388396
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Regulation of TP53 Activity R-HSA-5633007
Neurodegenerative Diseases R-HSA-8863678
Transcriptional Regulation by NPAS4 R-HSA-9634815
Semaphorin interactions R-HSA-373755
Activated NTRK2 signals through CDK5 R-HSA-9032845
Transcriptional Regulation by NPAS4 R-HSA-9634815
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Semaphorin interactions R-HSA-373755
Activated NTRK2 signals through CDK5 R-HSA-9032845
DARPP-32 events R-HSA-180024
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Axon guidance R-HSA-422475
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Signaling by NTRK1 (TRKA) R-HSA-187037
CRMPs in Sema3A signaling R-HSA-399956
Disease R-HSA-1643685
Diseases of programmed cell death R-HSA-9645723
Gene expression (Transcription) R-HSA-74160
G alpha (i) signalling events R-HSA-418594
Neurodegenerative Diseases R-HSA-8863678
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Generic Transcription Pathway R-HSA-212436
Signaling by GPCR R-HSA-372790
Regulation of TP53 Activity R-HSA-5633007
Signaling by NTRK2 (TRKB) R-HSA-9006115
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
NPAS4 regulates expression of target genes R-HSA-9768919
Developmental Biology R-HSA-1266738
Opioid Signalling R-HSA-111885
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Hemostasis R-HSA-109582
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
NGF-stimulated transcription R-HSA-9031628
Transcriptional Regulation by TP53 R-HSA-3700989
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by NTRKs R-HSA-166520
Opioid Signalling R-HSA-111885
Factors involved in megakaryocyte development and platelet production R-HSA-983231
CRMPs in Sema3A signaling R-HSA-399956
Regulation of TP53 Activity R-HSA-5633007
Transcriptional Regulation by NPAS4 R-HSA-9634815
Gene expression (Transcription) R-HSA-74160
Neurodegenerative Diseases R-HSA-8863678
Semaphorin interactions R-HSA-373755
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by NTRK1 (TRKA) R-HSA-187037
Generic Transcription Pathway R-HSA-212436
Axon guidance R-HSA-422475
NPAS4 regulates expression of target genes R-HSA-9768919
Hemostasis R-HSA-109582
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Activated NTRK2 signals through CDK5 R-HSA-9032845
DARPP-32 events R-HSA-180024
Signaling by GPCR R-HSA-372790
Disease R-HSA-1643685
Diseases of programmed cell death R-HSA-9645723
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
NGF-stimulated transcription R-HSA-9031628
Signaling by NTRK2 (TRKB) R-HSA-9006115
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Signaling by NTRK2 (TRKB) R-HSA-9006115
Generic Transcription Pathway R-HSA-212436
Semaphorin interactions R-HSA-373755
DARPP-32 events R-HSA-180024
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by GPCR R-HSA-372790
Diseases of programmed cell death R-HSA-9645723
NPAS4 regulates expression of target genes R-HSA-9768919
Neurodegenerative Diseases R-HSA-8863678
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Opioid Signalling R-HSA-111885
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Regulation of TP53 Activity R-HSA-5633007
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
G alpha (i) signalling events R-HSA-418594
Hemostasis R-HSA-109582
Disease R-HSA-1643685
NGF-stimulated transcription R-HSA-9031628
RNA Polymerase II Transcription R-HSA-73857
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Activated NTRK2 signals through CDK5 R-HSA-9032845
GPCR downstream signalling R-HSA-388396
Signaling by NTRKs R-HSA-166520
Transcriptional Regulation by NPAS4 R-HSA-9634815
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Nervous system development R-HSA-9675108
CRMPs in Sema3A signaling R-HSA-399956
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity R-HSA-5633007
Signaling by NTRKs R-HSA-166520
DARPP-32 events R-HSA-180024
Disease R-HSA-1643685
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Transcriptional Regulation by NPAS4 R-HSA-9634815
Transcriptional Regulation by TP53 R-HSA-3700989
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Hemostasis R-HSA-109582
Nervous system development R-HSA-9675108
Factors involved in megakaryocyte development and platelet production R-HSA-983231
CRMPs in Sema3A signaling R-HSA-399956
Activated NTRK2 signals through CDK5 R-HSA-9032845
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Semaphorin interactions R-HSA-373755
Diseases of programmed cell death R-HSA-9645723
Signaling by GPCR R-HSA-372790
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
NPAS4 regulates expression of target genes R-HSA-9768919
Opioid Signalling R-HSA-111885
Signaling by NTRK2 (TRKB) R-HSA-9006115
G alpha (i) signalling events R-HSA-418594
Gene expression (Transcription) R-HSA-74160
NGF-stimulated transcription R-HSA-9031628
Signaling by NTRK1 (TRKA) R-HSA-187037
Developmental Biology R-HSA-1266738
Neurodegenerative Diseases R-HSA-8863678
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NPAS4 regulates expression of target genes R-HSA-9768919
Transcriptional Regulation by TP53 R-HSA-3700989
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
NGF-stimulated transcription R-HSA-9031628
Signaling by NTRK2 (TRKB) R-HSA-9006115
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Hemostasis R-HSA-109582
Neurodegenerative Diseases R-HSA-8863678
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Opioid Signalling R-HSA-111885
GPCR downstream signalling R-HSA-388396
Developmental Biology R-HSA-1266738
Activated NTRK2 signals through CDK5 R-HSA-9032845
Regulation of TP53 Activity R-HSA-5633007
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by GPCR R-HSA-372790
Generic Transcription Pathway R-HSA-212436
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
DARPP-32 events R-HSA-180024
Transcriptional Regulation by NPAS4 R-HSA-9634815
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
G alpha (i) signalling events R-HSA-418594
CRMPs in Sema3A signaling R-HSA-399956
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
Signaling by NTRKs R-HSA-166520
Axon guidance R-HSA-422475
Semaphorin interactions R-HSA-373755
Diseases of programmed cell death R-HSA-9645723
NGF-stimulated transcription R-HSA-9031628
G alpha (i) signalling events R-HSA-418594
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Transcriptional Regulation by NPAS4 R-HSA-9634815
Diseases of programmed cell death R-HSA-9645723
Signaling by NTRK2 (TRKB) R-HSA-9006115
CRMPs in Sema3A signaling R-HSA-399956
RNA Polymerase II Transcription R-HSA-73857
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signal Transduction R-HSA-162582
Signaling by NTRK1 (TRKA) R-HSA-187037
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
GPCR downstream signalling R-HSA-388396
NPAS4 regulates expression of target genes R-HSA-9768919
Axon guidance R-HSA-422475
Opioid Signalling R-HSA-111885
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulation of TP53 Activity R-HSA-5633007
Activated NTRK2 signals through CDK5 R-HSA-9032845
Generic Transcription Pathway R-HSA-212436
Neurodegenerative Diseases R-HSA-8863678
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Hemostasis R-HSA-109582
Signaling by NTRKs R-HSA-166520
Semaphorin interactions R-HSA-373755
Signaling by GPCR R-HSA-372790
Gene expression (Transcription) R-HSA-74160
DARPP-32 events R-HSA-180024
Disease R-HSA-1643685
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Semaphorin interactions R-HSA-373755
Signaling by GPCR R-HSA-372790
NGF-stimulated transcription R-HSA-9031628
RNA Polymerase II Transcription R-HSA-73857
G alpha (i) signalling events R-HSA-418594
Axon guidance R-HSA-422475
Neurodegenerative Diseases R-HSA-8863678
DARPP-32 events R-HSA-180024
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by NTRK2 (TRKB) R-HSA-9006115
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Regulation of TP53 Activity R-HSA-5633007
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by NTRKs R-HSA-166520
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
CRMPs in Sema3A signaling R-HSA-399956
Disease R-HSA-1643685
Activated NTRK2 signals through CDK5 R-HSA-9032845
Opioid Signalling R-HSA-111885
Gene expression (Transcription) R-HSA-74160
GPCR downstream signalling R-HSA-388396
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Transcriptional Regulation by NPAS4 R-HSA-9634815
Diseases of programmed cell death R-HSA-9645723
Generic Transcription Pathway R-HSA-212436
Signaling by NTRK1 (TRKA) R-HSA-187037
Nervous system development R-HSA-9675108
NPAS4 regulates expression of target genes R-HSA-9768919
Hemostasis R-HSA-109582
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Regulation of TP53 Activity R-HSA-5633007
Developmental Biology R-HSA-1266738
Signaling by GPCR R-HSA-372790
Nervous system development R-HSA-9675108
Signaling by NTRK1 (TRKA) R-HSA-187037
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
DARPP-32 events R-HSA-180024
Hemostasis R-HSA-109582
Activated NTRK2 signals through CDK5 R-HSA-9032845
Signaling by NTRK2 (TRKB) R-HSA-9006115
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Transcriptional Regulation by NPAS4 R-HSA-9634815
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Opioid Signalling R-HSA-111885
GPCR downstream signalling R-HSA-388396
NPAS4 regulates expression of target genes R-HSA-9768919
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Diseases of programmed cell death R-HSA-9645723
Semaphorin interactions R-HSA-373755
Signaling by NTRKs R-HSA-166520
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Neurodegenerative Diseases R-HSA-8863678
NGF-stimulated transcription R-HSA-9031628
Disease R-HSA-1643685
G alpha (i) signalling events R-HSA-418594
Transcriptional Regulation by TP53 R-HSA-3700989
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000164885
NCBI gene (formerly Entrezgene) 1020
GeneCards 1774
HGNC Symbol HGNC:1774
MIM gene 123831
MIM morbid 616342
UniProtKB Gene Name Q00535
WikiGene 1020
Gene: AKT3
Ensembl ID : ENSG00000117020
Description: AKT serine/threonine kinase 3
Gene Synonyms: PKBG,PRKBG,RAC-GAMMA
14 APIs:
201 Possible Orthologues:

Intrinsic Pathway for Apoptosis R-HSA-109606
Cellular response to chemical stress R-HSA-9711123
Transcriptional Regulation by TP53 R-HSA-3700989
S Phase R-HSA-69242
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Apoptosis R-HSA-109581
Vesicle-mediated transport R-HSA-5653656
GPCR downstream signalling R-HSA-388396
Signaling by VEGF R-HSA-194138
Gene expression (Transcription) R-HSA-74160
TP53 Regulates Metabolic Genes R-HSA-5628897
Cellular responses to stress R-HSA-2262752
AKT-mediated inactivation of FOXO1A R-HSA-211163
Costimulation by the CD28 family R-HSA-388841
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by GPCR R-HSA-372790
Downregulation of ERBB2 signaling R-HSA-8863795
PIP3 activates AKT signaling R-HSA-1257604
AKT phosphorylates targets in the cytosol R-HSA-198323
Regulation of beta-cell development R-HSA-186712
Regulation of TP53 Expression and Degradation R-HSA-6806003
G-protein beta:gamma signalling R-HSA-397795
Transcriptional regulation by RUNX2 R-HSA-8878166
Rab regulation of trafficking R-HSA-9007101
Generic Transcription Pathway R-HSA-212436
SARS-CoV-2 Infection R-HSA-9694516
Cytokine Signaling in Immune system R-HSA-1280215
RUNX2 regulates genes involved in cell migration R-HSA-8941332
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
PTEN Regulation R-HSA-6807070
Disease R-HSA-1643685
SARS-CoV Infections R-HSA-9679506
Membrane Trafficking R-HSA-199991
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of TP53 Activity R-HSA-5633007
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
G1/S Transition R-HSA-69206
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
CD28 co-stimulation R-HSA-389356
Signal Transduction R-HSA-162582
ESR-mediated signaling R-HSA-8939211
Signaling by Nuclear Receptors R-HSA-9006931
Negative regulation of the PI3K/AKT network R-HSA-199418
FLT3 Signaling R-HSA-9607240
SARS-CoV-2-host interactions R-HSA-9705683
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K/AKT Signaling in Cancer R-HSA-2219528
Activation of BAD and translocation to mitochondria R-HSA-111447
VEGFR2 mediated vascular permeability R-HSA-5218920
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stimuli R-HSA-8953897
Activation of BH3-only proteins R-HSA-114452
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle R-HSA-1640170
AKT phosphorylates targets in the nucleus R-HSA-198693
Regulation of localization of FOXO transcription factors R-HSA-9614399
Infectious disease R-HSA-5663205
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity through Acetylation R-HSA-6804758
G beta:gamma signalling through PI3Kgamma R-HSA-392451
CTLA4 inhibitory signaling R-HSA-389513
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ERBB2 R-HSA-1227986
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Immune System R-HSA-168256
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Adaptive Immune System R-HSA-1280218
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
FOXO-mediated transcription R-HSA-9614085
Regulation of TP53 Degradation R-HSA-6804757
Programmed Cell Death R-HSA-5357801
Extra-nuclear estrogen signaling R-HSA-9009391
Regulation of gene expression in beta cells R-HSA-210745
VEGFA-VEGFR2 Pathway R-HSA-4420097
Regulation of PTEN stability and activity R-HSA-8948751
Intrinsic Pathway for Apoptosis R-HSA-109606
GPCR downstream signalling R-HSA-388396
Extra-nuclear estrogen signaling R-HSA-9009391
Downregulation of ERBB2 signaling R-HSA-8863795
Cellular responses to stimuli R-HSA-8953897
G1/S Transition R-HSA-69206
VEGFA-VEGFR2 Pathway R-HSA-4420097
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Nuclear Receptors R-HSA-9006931
CD28 co-stimulation R-HSA-389356
Infectious disease R-HSA-5663205
Regulation of gene expression in beta cells R-HSA-210745
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
PI3K/AKT Signaling in Cancer R-HSA-2219528
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Transcriptional regulation by RUNX2 R-HSA-8878166
Generic Transcription Pathway R-HSA-212436
Activation of BAD and translocation to mitochondria R-HSA-111447
AKT phosphorylates targets in the nucleus R-HSA-198693
CTLA4 inhibitory signaling R-HSA-389513
FLT3 Signaling R-HSA-9607240
Regulation of localization of FOXO transcription factors R-HSA-9614399
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Intracellular signaling by second messengers R-HSA-9006925
Signaling by GPCR R-HSA-372790
Programmed Cell Death R-HSA-5357801
SARS-CoV-2 Infection R-HSA-9694516
Regulation of TP53 Degradation R-HSA-6804757
Cell Cycle, Mitotic R-HSA-69278
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
S Phase R-HSA-69242
Membrane Trafficking R-HSA-199991
SARS-CoV-2-host interactions R-HSA-9705683
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Vesicle-mediated transport R-HSA-5653656
Signaling by ERBB2 R-HSA-1227986
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Expression and Degradation R-HSA-6806003
FOXO-mediated transcription R-HSA-9614085
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Costimulation by the CD28 family R-HSA-388841
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity R-HSA-5633007
KEAP1-NFE2L2 pathway R-HSA-9755511
AKT phosphorylates targets in the cytosol R-HSA-198323
PTEN Regulation R-HSA-6807070
Regulation of beta-cell development R-HSA-186712
Apoptosis R-HSA-109581
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of the PI3K/AKT network R-HSA-199418
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Adaptive Immune System R-HSA-1280218
Transcriptional Regulation by TP53 R-HSA-3700989
TP53 Regulates Metabolic Genes R-HSA-5628897
Regulation of TP53 Activity through Acetylation R-HSA-6804758
AKT-mediated inactivation of FOXO1A R-HSA-211163
Activation of BH3-only proteins R-HSA-114452
Developmental Biology R-HSA-1266738
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stress R-HSA-2262752
SARS-CoV Infections R-HSA-9679506
VEGFR2 mediated vascular permeability R-HSA-5218920
Immune System R-HSA-168256
Rab regulation of trafficking R-HSA-9007101
ESR-mediated signaling R-HSA-8939211
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Cellular response to chemical stress R-HSA-9711123
G-protein beta:gamma signalling R-HSA-397795
CD28 dependent PI3K/Akt signaling R-HSA-389357
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Mitotic G1 phase and G1/S transition R-HSA-453279
Disease R-HSA-1643685
G-protein beta:gamma signalling R-HSA-397795
Regulation of gene expression in beta cells R-HSA-210745
Vesicle-mediated transport R-HSA-5653656
Apoptosis R-HSA-109581
S Phase R-HSA-69242
Gene expression (Transcription) R-HSA-74160
GPCR downstream signalling R-HSA-388396
Intrinsic Pathway for Apoptosis R-HSA-109606
Cellular response to chemical stress R-HSA-9711123
Regulation of TP53 Expression and Degradation R-HSA-6806003
VEGFR2 mediated vascular permeability R-HSA-5218920
FLT3 Signaling R-HSA-9607240
Cell Cycle R-HSA-1640170
Intracellular signaling by second messengers R-HSA-9006925
Regulation of localization of FOXO transcription factors R-HSA-9614399
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by ERBB2 R-HSA-1227986
AKT phosphorylates targets in the cytosol R-HSA-198323
Costimulation by the CD28 family R-HSA-388841
Regulation of TP53 Activity R-HSA-5633007
Mitotic G1 phase and G1/S transition R-HSA-453279
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
AKT-mediated inactivation of FOXO1A R-HSA-211163
SARS-CoV-2 Infection R-HSA-9694516
RNA Polymerase II Transcription R-HSA-73857
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regulation of beta-cell development R-HSA-186712
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Extra-nuclear estrogen signaling R-HSA-9009391
Cellular responses to stimuli R-HSA-8953897
G1/S Transition R-HSA-69206
Regulation of TP53 Degradation R-HSA-6804757
Cellular responses to stress R-HSA-2262752
CD28 co-stimulation R-HSA-389356
CTLA4 inhibitory signaling R-HSA-389513
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Nuclear Receptors R-HSA-9006931
Developmental Biology R-HSA-1266738
CD28 dependent PI3K/Akt signaling R-HSA-389357
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Downregulation of ERBB2 signaling R-HSA-8863795
Rab regulation of trafficking R-HSA-9007101
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Membrane Trafficking R-HSA-199991
Transcriptional Regulation by TP53 R-HSA-3700989
SARS-CoV Infections R-HSA-9679506
TP53 Regulates Metabolic Genes R-HSA-5628897
Immune System R-HSA-168256
Negative regulation of the PI3K/AKT network R-HSA-199418
SARS-CoV-2-host interactions R-HSA-9705683
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
VEGFA-VEGFR2 Pathway R-HSA-4420097
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Generic Transcription Pathway R-HSA-212436
Regulation of PTEN stability and activity R-HSA-8948751
KEAP1-NFE2L2 pathway R-HSA-9755511
Activation of BH3-only proteins R-HSA-114452
Programmed Cell Death R-HSA-5357801
FOXO-mediated transcription R-HSA-9614085
AKT phosphorylates targets in the nucleus R-HSA-198693
ESR-mediated signaling R-HSA-8939211
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Cell Cycle, Mitotic R-HSA-69278
PTEN Regulation R-HSA-6807070
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by GPCR R-HSA-372790
Activation of BAD and translocation to mitochondria R-HSA-111447
Disease R-HSA-1643685
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
FLT3 Signaling R-HSA-9607240
CD28 co-stimulation R-HSA-389356
RUNX2 regulates genes involved in cell migration R-HSA-8941332
PTEN Regulation R-HSA-6807070
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Signaling by GPCR R-HSA-372790
VEGFR2 mediated vascular permeability R-HSA-5218920
FOXO-mediated transcription R-HSA-9614085
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by VEGF R-HSA-194138
Developmental Biology R-HSA-1266738
Cyclin E associated events during G1/S transition R-HSA-69202
Costimulation by the CD28 family R-HSA-388841
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
TP53 Regulates Metabolic Genes R-HSA-5628897
SARS-CoV Infections R-HSA-9679506
Extra-nuclear estrogen signaling R-HSA-9009391
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regulation of beta-cell development R-HSA-186712
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G-protein beta:gamma signalling R-HSA-397795
Signaling by Nuclear Receptors R-HSA-9006931
Transcriptional Regulation by TP53 R-HSA-3700989
Disease R-HSA-1643685
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of gene expression in beta cells R-HSA-210745
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Mitotic G1 phase and G1/S transition R-HSA-453279
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
AKT phosphorylates targets in the nucleus R-HSA-198693
Regulation of TP53 Expression and Degradation R-HSA-6806003
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulation of localization of FOXO transcription factors R-HSA-9614399
Apoptosis R-HSA-109581
Cell Cycle R-HSA-1640170
GPCR downstream signalling R-HSA-388396
Downregulation of ERBB2 signaling R-HSA-8863795
Vesicle-mediated transport R-HSA-5653656
ESR-mediated signaling R-HSA-8939211
Gene expression (Transcription) R-HSA-74160
VEGFA-VEGFR2 Pathway R-HSA-4420097
Regulation of TP53 Activity R-HSA-5633007
CD28 dependent PI3K/Akt signaling R-HSA-389357
Activation of BAD and translocation to mitochondria R-HSA-111447
Membrane Trafficking R-HSA-199991
Regulation of TP53 Degradation R-HSA-6804757
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Signal Transduction R-HSA-162582
Activation of BH3-only proteins R-HSA-114452
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Programmed Cell Death R-HSA-5357801
SARS-CoV-2-host interactions R-HSA-9705683
S Phase R-HSA-69242
Rab regulation of trafficking R-HSA-9007101
Adaptive Immune System R-HSA-1280218
Cellular response to chemical stress R-HSA-9711123
CTLA4 inhibitory signaling R-HSA-389513
SARS-CoV-2 Infection R-HSA-9694516
Infectious disease R-HSA-5663205
G1/S Transition R-HSA-69206
AKT-mediated inactivation of FOXO1A R-HSA-211163
Signaling by ERBB2 R-HSA-1227986
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
AKT phosphorylates targets in the cytosol R-HSA-198323
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
PIP3 activates AKT signaling R-HSA-1257604
Cellular responses to stimuli R-HSA-8953897
Disease R-HSA-1643685
Membrane Trafficking R-HSA-199991
G1/S Transition R-HSA-69206
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SARS-CoV-2-host interactions R-HSA-9705683
Signal Transduction R-HSA-162582
Apoptosis R-HSA-109581
G-protein beta:gamma signalling R-HSA-397795
Infectious disease R-HSA-5663205
Regulation of gene expression in beta cells R-HSA-210745
Regulation of localization of FOXO transcription factors R-HSA-9614399
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Extra-nuclear estrogen signaling R-HSA-9009391
Cell Cycle, Mitotic R-HSA-69278
Vesicle-mediated transport R-HSA-5653656
KEAP1-NFE2L2 pathway R-HSA-9755511
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity R-HSA-5633007
Programmed Cell Death R-HSA-5357801
FOXO-mediated transcription R-HSA-9614085
AKT-mediated inactivation of FOXO1A R-HSA-211163
PTEN Regulation R-HSA-6807070
VEGFA-VEGFR2 Pathway R-HSA-4420097
Transcriptional regulation by RUNX2 R-HSA-8878166
CTLA4 inhibitory signaling R-HSA-389513
Transcriptional Regulation by TP53 R-HSA-3700989
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Negative regulation of the PI3K/AKT network R-HSA-199418
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
CD28 dependent PI3K/Akt signaling R-HSA-389357
ESR-mediated signaling R-HSA-8939211
CD28 co-stimulation R-HSA-389356
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
VEGFR2 mediated vascular permeability R-HSA-5218920
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Regulation of PTEN stability and activity R-HSA-8948751
GPCR downstream signalling R-HSA-388396
Developmental Biology R-HSA-1266738
FLT3 Signaling R-HSA-9607240
Activation of BH3-only proteins R-HSA-114452
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Immune System R-HSA-168256
Activation of BAD and translocation to mitochondria R-HSA-111447
S Phase R-HSA-69242
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Regulation of TP53 Expression and Degradation R-HSA-6806003
Intracellular signaling by second messengers R-HSA-9006925
Cellular response to chemical stress R-HSA-9711123
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by GPCR R-HSA-372790
AKT phosphorylates targets in the cytosol R-HSA-198323
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Adaptive Immune System R-HSA-1280218
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Intrinsic Pathway for Apoptosis R-HSA-109606
Cellular responses to stress R-HSA-2262752
AKT phosphorylates targets in the nucleus R-HSA-198693
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stimuli R-HSA-8953897
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by VEGF R-HSA-194138
Cytokine Signaling in Immune system R-HSA-1280215
TP53 Regulates Metabolic Genes R-HSA-5628897
Signaling by ERBB2 R-HSA-1227986
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
PIP3 activates AKT signaling R-HSA-1257604
Regulation of beta-cell development R-HSA-186712
Costimulation by the CD28 family R-HSA-388841
SARS-CoV Infections R-HSA-9679506
Rab regulation of trafficking R-HSA-9007101
RNA Polymerase II Transcription R-HSA-73857
Signaling by Nuclear Receptors R-HSA-9006931
SARS-CoV-2 Infection R-HSA-9694516
Downregulation of ERBB2 signaling R-HSA-8863795
Transcriptional regulation by RUNX2 R-HSA-8878166
GPCR downstream signalling R-HSA-388396
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
S Phase R-HSA-69242
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of beta-cell development R-HSA-186712
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Extra-nuclear estrogen signaling R-HSA-9009391
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
PI3K/AKT Signaling in Cancer R-HSA-2219528
CD28 co-stimulation R-HSA-389356
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Adaptive Immune System R-HSA-1280218
Activation of BAD and translocation to mitochondria R-HSA-111447
SARS-CoV-2-host interactions R-HSA-9705683
G1/S Transition R-HSA-69206
Downregulation of ERBB2 signaling R-HSA-8863795
RNA Polymerase II Transcription R-HSA-73857
Mitotic G1 phase and G1/S transition R-HSA-453279
VEGFA-VEGFR2 Pathway R-HSA-4420097
SARS-CoV Infections R-HSA-9679506
Cell Cycle, Mitotic R-HSA-69278
Regulation of gene expression in beta cells R-HSA-210745
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
VEGFR2 mediated vascular permeability R-HSA-5218920
Programmed Cell Death R-HSA-5357801
Cellular responses to stress R-HSA-2262752
Activation of BH3-only proteins R-HSA-114452
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
AKT-mediated inactivation of FOXO1A R-HSA-211163
TP53 Regulates Metabolic Genes R-HSA-5628897
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
AKT phosphorylates targets in the cytosol R-HSA-198323
Negative regulation of the PI3K/AKT network R-HSA-199418
Immune System R-HSA-168256
PIP3 activates AKT signaling R-HSA-1257604
Membrane Trafficking R-HSA-199991
Cellular response to chemical stress R-HSA-9711123
Signaling by GPCR R-HSA-372790
Cyclin E associated events during G1/S transition R-HSA-69202
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Generic Transcription Pathway R-HSA-212436
FLT3 Signaling R-HSA-9607240
Costimulation by the CD28 family R-HSA-388841
Regulation of localization of FOXO transcription factors R-HSA-9614399
Intrinsic Pathway for Apoptosis R-HSA-109606
ESR-mediated signaling R-HSA-8939211
FOXO-mediated transcription R-HSA-9614085
Apoptosis R-HSA-109581
PTEN Regulation R-HSA-6807070
Signaling by Nuclear Receptors R-HSA-9006931
Vesicle-mediated transport R-HSA-5653656
Transcriptional Regulation by TP53 R-HSA-3700989
G beta:gamma signalling through PI3Kgamma R-HSA-392451
AKT phosphorylates targets in the nucleus R-HSA-198693
G-protein beta:gamma signalling R-HSA-397795
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of TP53 Activity R-HSA-5633007
CTLA4 inhibitory signaling R-HSA-389513
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Regulation of TP53 Expression and Degradation R-HSA-6806003
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle R-HSA-1640170
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Signaling by VEGF R-HSA-194138
KEAP1-NFE2L2 pathway R-HSA-9755511
Rab regulation of trafficking R-HSA-9007101
Signaling by ERBB2 R-HSA-1227986
CD28 dependent PI3K/Akt signaling R-HSA-389357
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Regulation of TP53 Degradation R-HSA-6804757
SARS-CoV-2 Infection R-HSA-9694516
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Developmental Biology R-HSA-1266738
G-protein beta:gamma signalling R-HSA-397795
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Negative regulation of the PI3K/AKT network R-HSA-199418
CD28 dependent PI3K/Akt signaling R-HSA-389357
Costimulation by the CD28 family R-HSA-388841
PI3K/AKT Signaling in Cancer R-HSA-2219528
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by ERBB2 R-HSA-1227986
KEAP1-NFE2L2 pathway R-HSA-9755511
PTEN Regulation R-HSA-6807070
Activation of BAD and translocation to mitochondria R-HSA-111447
PIP3 activates AKT signaling R-HSA-1257604
SARS-CoV-2-host interactions R-HSA-9705683
Vesicle-mediated transport R-HSA-5653656
Signaling by Nuclear Receptors R-HSA-9006931
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Regulation of localization of FOXO transcription factors R-HSA-9614399
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Membrane Trafficking R-HSA-199991
Cyclin E associated events during G1/S transition R-HSA-69202
AKT phosphorylates targets in the cytosol R-HSA-198323
Generic Transcription Pathway R-HSA-212436
Regulation of gene expression in beta cells R-HSA-210745
Regulation of TP53 Expression and Degradation R-HSA-6806003
Signaling by GPCR R-HSA-372790
Rab regulation of trafficking R-HSA-9007101
CD28 co-stimulation R-HSA-389356
FOXO-mediated transcription R-HSA-9614085
FLT3 Signaling R-HSA-9607240
GPCR downstream signalling R-HSA-388396
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Cell Cycle, Mitotic R-HSA-69278
TP53 Regulates Metabolic Genes R-HSA-5628897
Disease R-HSA-1643685
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
ESR-mediated signaling R-HSA-8939211
Transcriptional regulation by RUNX2 R-HSA-8878166
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Infectious disease R-HSA-5663205
Signaling by VEGF R-HSA-194138
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Apoptosis R-HSA-109581
VEGFA-VEGFR2 Pathway R-HSA-4420097
Intrinsic Pathway for Apoptosis R-HSA-109606
SARS-CoV Infections R-HSA-9679506
AKT-mediated inactivation of FOXO1A R-HSA-211163
Cell Cycle R-HSA-1640170
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
CTLA4 inhibitory signaling R-HSA-389513
Extra-nuclear estrogen signaling R-HSA-9009391
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S Transition R-HSA-69206
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGFR2 mediated vascular permeability R-HSA-5218920
Cytokine Signaling in Immune system R-HSA-1280215
SARS-CoV-2 Infection R-HSA-9694516
Downregulation of ERBB2 signaling R-HSA-8863795
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
Regulation of beta-cell development R-HSA-186712
Mitotic G1 phase and G1/S transition R-HSA-453279
Signal Transduction R-HSA-162582
AKT phosphorylates targets in the nucleus R-HSA-198693
Regulation of TP53 Degradation R-HSA-6804757
Activation of BH3-only proteins R-HSA-114452
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Cellular response to chemical stress R-HSA-9711123
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cellular responses to stress R-HSA-2262752
S Phase R-HSA-69242
Adaptive Immune System R-HSA-1280218
PIP3 activates AKT signaling R-HSA-1257604
Intrinsic Pathway for Apoptosis R-HSA-109606
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Membrane Trafficking R-HSA-199991
FLT3 Signaling R-HSA-9607240
TP53 Regulates Metabolic Genes R-HSA-5628897
Regulation of TP53 Activity through Acetylation R-HSA-6804758
SARS-CoV Infections R-HSA-9679506
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of TP53 Expression and Degradation R-HSA-6806003
Signaling by ERBB2 R-HSA-1227986
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SARS-CoV-2-host interactions R-HSA-9705683
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
ESR-mediated signaling R-HSA-8939211
CTLA4 inhibitory signaling R-HSA-389513
Costimulation by the CD28 family R-HSA-388841
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Nuclear Receptors R-HSA-9006931
CD28 co-stimulation R-HSA-389356
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Cytokine Signaling in Immune system R-HSA-1280215
Programmed Cell Death R-HSA-5357801
PTEN Regulation R-HSA-6807070
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Cell Cycle R-HSA-1640170
RUNX2 regulates genes involved in cell migration R-HSA-8941332
FOXO-mediated transcription R-HSA-9614085
G beta:gamma signalling through PI3Kgamma R-HSA-392451
AKT-mediated inactivation of FOXO1A R-HSA-211163
Vesicle-mediated transport R-HSA-5653656
Activation of BH3-only proteins R-HSA-114452
Apoptosis R-HSA-109581
S Phase R-HSA-69242
Transcriptional Regulation by TP53 R-HSA-3700989
Activation of BAD and translocation to mitochondria R-HSA-111447
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cellular response to chemical stress R-HSA-9711123
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Regulation of beta-cell development R-HSA-186712
Regulation of gene expression in beta cells R-HSA-210745
AKT phosphorylates targets in the nucleus R-HSA-198693
GPCR downstream signalling R-HSA-388396
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of TP53 Activity R-HSA-5633007
VEGFR2 mediated vascular permeability R-HSA-5218920
CD28 dependent PI3K/Akt signaling R-HSA-389357
Cellular responses to stimuli R-HSA-8953897
Rab regulation of trafficking R-HSA-9007101
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Degradation R-HSA-6804757
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G1 phase and G1/S transition R-HSA-453279
Gene expression (Transcription) R-HSA-74160
G-protein beta:gamma signalling R-HSA-397795
SARS-CoV-2 Infection R-HSA-9694516
Negative regulation of the PI3K/AKT network R-HSA-199418
Extra-nuclear estrogen signaling R-HSA-9009391
AKT phosphorylates targets in the cytosol R-HSA-198323
Signaling by GPCR R-HSA-372790
VEGFA-VEGFR2 Pathway R-HSA-4420097
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
Regulation of localization of FOXO transcription factors R-HSA-9614399
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
Immune System R-HSA-168256
Signaling by VEGF R-HSA-194138
Developmental Biology R-HSA-1266738
Regulation of PTEN stability and activity R-HSA-8948751
Downregulation of ERBB2 signaling R-HSA-8863795
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
Activation of BAD and translocation to mitochondria R-HSA-111447
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Immune System R-HSA-168256
CD28 co-stimulation R-HSA-389356
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGFR2 mediated vascular permeability R-HSA-5218920
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Activation of BH3-only proteins R-HSA-114452
Regulation of TP53 Activity R-HSA-5633007
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
G-protein beta:gamma signalling R-HSA-397795
AKT phosphorylates targets in the nucleus R-HSA-198693
FLT3 Signaling R-HSA-9607240
Signaling by ERBB2 R-HSA-1227986
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Apoptosis R-HSA-109581
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV Infections R-HSA-9679506
ESR-mediated signaling R-HSA-8939211
Membrane Trafficking R-HSA-199991
Regulation of localization of FOXO transcription factors R-HSA-9614399
Intrinsic Pathway for Apoptosis R-HSA-109606
CD28 dependent PI3K/Akt signaling R-HSA-389357
Rab regulation of trafficking R-HSA-9007101
Regulation of TP53 Degradation R-HSA-6804757
Extra-nuclear estrogen signaling R-HSA-9009391
Disease R-HSA-1643685
Gene expression (Transcription) R-HSA-74160
SARS-CoV-2-host interactions R-HSA-9705683
Regulation of gene expression in beta cells R-HSA-210745
Negative regulation of the PI3K/AKT network R-HSA-199418
Cyclin E associated events during G1/S transition R-HSA-69202
RNA Polymerase II Transcription R-HSA-73857
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Signaling by VEGF R-HSA-194138
Downregulation of ERBB2 signaling R-HSA-8863795
Mitotic G1 phase and G1/S transition R-HSA-453279
SARS-CoV-2 Infection R-HSA-9694516
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cell Cycle R-HSA-1640170
Intracellular signaling by second messengers R-HSA-9006925
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
Cellular response to chemical stress R-HSA-9711123
FOXO-mediated transcription R-HSA-9614085
AKT-mediated inactivation of FOXO1A R-HSA-211163
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Transcriptional Regulation by TP53 R-HSA-3700989
Costimulation by the CD28 family R-HSA-388841
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
Signal Transduction R-HSA-162582
TP53 Regulates Metabolic Genes R-HSA-5628897
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K/AKT Signaling in Cancer R-HSA-2219528
S Phase R-HSA-69242
AKT phosphorylates targets in the cytosol R-HSA-198323
Regulation of beta-cell development R-HSA-186712
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by GPCR R-HSA-372790
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
CTLA4 inhibitory signaling R-HSA-389513
GPCR downstream signalling R-HSA-388396
Transcriptional regulation by RUNX2 R-HSA-8878166
KEAP1-NFE2L2 pathway R-HSA-9755511
G1/S Transition R-HSA-69206
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Regulation of TP53 Expression and Degradation R-HSA-6806003
Vesicle-mediated transport R-HSA-5653656
Signaling by Nuclear Receptors R-HSA-9006931

Expression Atlas ENSG00000117020
LRG display in Ensembl gene LRG_1396
NCBI gene (formerly Entrezgene) 10000
GeneCards 393
HGNC Symbol HGNC:393
MIM gene 611223
MIM morbid 615937
UniProtKB Gene Name Q9Y243
WikiGene 10000
Gene: YES1
Ensembl ID : ENSG00000176105
Description: YES proto-oncogene 1, Src family tyrosine kinase
Gene Synonyms: C-YES,HST441,YES
1 APIs:
258 Possible Orthologues:

Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
RUNX2 regulates osteoblast differentiation R-HSA-8940973
PECAM1 interactions R-HSA-210990
Adaptive Immune System R-HSA-1280218
EPHB-mediated forward signaling R-HSA-3928662
Parasite infection R-HSA-9664407
Generic Transcription Pathway R-HSA-212436
EPH-ephrin mediated repulsion of cells R-HSA-3928665
FCGR3A-mediated phagocytosis R-HSA-9664422
Nervous system development R-HSA-9675108
Signaling by ERBB2 R-HSA-1227986
Regulation of signaling by CBL R-HSA-912631
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Axon guidance R-HSA-422475
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Cytokine Signaling in Immune system R-HSA-1280215
Gene expression (Transcription) R-HSA-74160
FCGR activation R-HSA-2029481
RUNX2 regulates bone development R-HSA-8941326
Regulation of KIT signaling R-HSA-1433559
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Leishmania infection R-HSA-9658195
Leishmania parasite growth and survival R-HSA-9664433
Signaling by SCF-KIT R-HSA-1433557
Signaling by KIT in disease R-HSA-9669938
CTLA4 inhibitory signaling R-HSA-389513
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
EPHA-mediated growth cone collapse R-HSA-3928663
Costimulation by the CD28 family R-HSA-388841
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Leishmania phagocytosis R-HSA-9664417
Disease R-HSA-1643685
Cell surface interactions at the vascular wall R-HSA-202733
Transcriptional regulation by RUNX2 R-HSA-8878166
CD28 co-stimulation R-HSA-389356
Developmental Biology R-HSA-1266738
RNA Polymerase II Transcription R-HSA-73857
Hemostasis R-HSA-109582
Innate Immune System R-HSA-168249
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PECAM1 interactions R-HSA-210990
EPH-Ephrin signaling R-HSA-2682334
Axon guidance R-HSA-422475
Adaptive Immune System R-HSA-1280218
Parasite infection R-HSA-9664407
CD28 co-stimulation R-HSA-389356
EPHA-mediated growth cone collapse R-HSA-3928663
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by KIT in disease R-HSA-9669938
Costimulation by the CD28 family R-HSA-388841
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Gene expression (Transcription) R-HSA-74160
Leishmania infection R-HSA-9658195
CTLA4 inhibitory signaling R-HSA-389513
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX2 R-HSA-8878166
Nervous system development R-HSA-9675108
Leishmania parasite growth and survival R-HSA-9664433
Hemostasis R-HSA-109582
EPHB-mediated forward signaling R-HSA-3928662
Regulation of KIT signaling R-HSA-1433559
RUNX2 regulates bone development R-HSA-8941326
Innate Immune System R-HSA-168249
Signaling by ERBB2 R-HSA-1227986
Immune System R-HSA-168256
FCGR3A-mediated phagocytosis R-HSA-9664422
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Signal Transduction R-HSA-162582
Leishmania phagocytosis R-HSA-9664417
Generic Transcription Pathway R-HSA-212436
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Disease R-HSA-1643685
Cell surface interactions at the vascular wall R-HSA-202733
Regulation of signaling by CBL R-HSA-912631
Signaling by Interleukins R-HSA-449147
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
FCGR activation R-HSA-2029481
Signaling by SCF-KIT R-HSA-1433557
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Developmental Biology R-HSA-1266738
RNA Polymerase II Transcription R-HSA-73857
Cytokine Signaling in Immune system R-HSA-1280215
Parasite infection R-HSA-9664407
EPHB-mediated forward signaling R-HSA-3928662
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of signaling by CBL R-HSA-912631
RUNX2 regulates osteoblast differentiation R-HSA-8940973
CD28 co-stimulation R-HSA-389356
Adaptive Immune System R-HSA-1280218
Leishmania parasite growth and survival R-HSA-9664433
Costimulation by the CD28 family R-HSA-388841
Nervous system development R-HSA-9675108
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
RUNX2 regulates bone development R-HSA-8941326
FCGR activation R-HSA-2029481
Signaling by ERBB2 R-HSA-1227986
Signaling by Interleukins R-HSA-449147
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
EPHA-mediated growth cone collapse R-HSA-3928663
FCGR3A-mediated phagocytosis R-HSA-9664422
Immune System R-HSA-168256
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
RNA Polymerase II Transcription R-HSA-73857
Leishmania infection R-HSA-9658195
Innate Immune System R-HSA-168249
Signaling by SCF-KIT R-HSA-1433557
Gene expression (Transcription) R-HSA-74160
CTLA4 inhibitory signaling R-HSA-389513
PECAM1 interactions R-HSA-210990
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX2 R-HSA-8878166
Axon guidance R-HSA-422475
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by KIT in disease R-HSA-9669938
Infectious disease R-HSA-5663205
Cytokine Signaling in Immune system R-HSA-1280215
Leishmania phagocytosis R-HSA-9664417
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Regulation of KIT signaling R-HSA-1433559
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Hemostasis R-HSA-109582
EPH-Ephrin signaling R-HSA-2682334
FCGR3A-mediated phagocytosis R-HSA-9664422
Signal Transduction R-HSA-162582
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Signaling by KIT in disease R-HSA-9669938
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Nervous system development R-HSA-9675108
Regulation of signaling by CBL R-HSA-912631
RNA Polymerase II Transcription R-HSA-73857
Cell surface interactions at the vascular wall R-HSA-202733
Cytokine Signaling in Immune system R-HSA-1280215
Gene expression (Transcription) R-HSA-74160
CTLA4 inhibitory signaling R-HSA-389513
Disease R-HSA-1643685
CD28 co-stimulation R-HSA-389356
Axon guidance R-HSA-422475
EPHB-mediated forward signaling R-HSA-3928662
Innate Immune System R-HSA-168249
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Costimulation by the CD28 family R-HSA-388841
Adaptive Immune System R-HSA-1280218
Developmental Biology R-HSA-1266738
Signaling by ERBB2 R-HSA-1227986
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
EPH-Ephrin signaling R-HSA-2682334
Parasite infection R-HSA-9664407
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by SCF-KIT R-HSA-1433557
EPHA-mediated growth cone collapse R-HSA-3928663
Transcriptional regulation by RUNX2 R-HSA-8878166
Immune System R-HSA-168256
Hemostasis R-HSA-109582
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Signaling by Interleukins R-HSA-449147
Leishmania parasite growth and survival R-HSA-9664433
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Generic Transcription Pathway R-HSA-212436
PECAM1 interactions R-HSA-210990
RUNX2 regulates bone development R-HSA-8941326
Leishmania infection R-HSA-9658195
Regulation of KIT signaling R-HSA-1433559
Leishmania phagocytosis R-HSA-9664417
FCGR activation R-HSA-2029481
Infectious disease R-HSA-5663205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
CD28 co-stimulation R-HSA-389356
Cell surface interactions at the vascular wall R-HSA-202733
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Axon guidance R-HSA-422475
EPHA-mediated growth cone collapse R-HSA-3928663
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by KIT in disease R-HSA-9669938
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Signaling by ERBB2 R-HSA-1227986
PECAM1 interactions R-HSA-210990
Hemostasis R-HSA-109582
CTLA4 inhibitory signaling R-HSA-389513
Generic Transcription Pathway R-HSA-212436
EPH-Ephrin signaling R-HSA-2682334
Leishmania infection R-HSA-9658195
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Immune System R-HSA-168256
FCGR activation R-HSA-2029481
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by SCF-KIT R-HSA-1433557
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Innate Immune System R-HSA-168249
Costimulation by the CD28 family R-HSA-388841
Parasite infection R-HSA-9664407
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Regulation of signaling by CBL R-HSA-912631
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Regulation of KIT signaling R-HSA-1433559
Leishmania parasite growth and survival R-HSA-9664433
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FCGR3A-mediated IL10 synthesis R-HSA-9664323
EPHB-mediated forward signaling R-HSA-3928662
Developmental Biology R-HSA-1266738
RUNX2 regulates bone development R-HSA-8941326
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
Leishmania phagocytosis R-HSA-9664417
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Immune System R-HSA-168256
Signaling by ERBB2 R-HSA-1227986
CD28 co-stimulation R-HSA-389356
Transcriptional regulation by RUNX2 R-HSA-8878166
Generic Transcription Pathway R-HSA-212436
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
EPHA-mediated growth cone collapse R-HSA-3928663
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signal Transduction R-HSA-162582
FCGR3A-mediated phagocytosis R-HSA-9664422
Disease R-HSA-1643685
Regulation of signaling by CBL R-HSA-912631
FCGR activation R-HSA-2029481
Leishmania phagocytosis R-HSA-9664417
Regulation of KIT signaling R-HSA-1433559
Infectious disease R-HSA-5663205
CTLA4 inhibitory signaling R-HSA-389513
Costimulation by the CD28 family R-HSA-388841
Axon guidance R-HSA-422475
EPH-Ephrin signaling R-HSA-2682334
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Innate Immune System R-HSA-168249
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Developmental Biology R-HSA-1266738
Signaling by SCF-KIT R-HSA-1433557
Nervous system development R-HSA-9675108
Leishmania parasite growth and survival R-HSA-9664433
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
RNA Polymerase II Transcription R-HSA-73857
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Signaling by KIT in disease R-HSA-9669938
Adaptive Immune System R-HSA-1280218
Hemostasis R-HSA-109582
RUNX2 regulates bone development R-HSA-8941326
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
PECAM1 interactions R-HSA-210990
Leishmania infection R-HSA-9658195
Parasite infection R-HSA-9664407
EPHB-mediated forward signaling R-HSA-3928662
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Gene expression (Transcription) R-HSA-74160
Cell surface interactions at the vascular wall R-HSA-202733
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
CD28 co-stimulation R-HSA-389356
PECAM1 interactions R-HSA-210990
Generic Transcription Pathway R-HSA-212436
FCGR3A-mediated IL10 synthesis R-HSA-9664323
RNA Polymerase II Transcription R-HSA-73857
Regulation of KIT signaling R-HSA-1433559
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Nervous system development R-HSA-9675108
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Signaling by SCF-KIT R-HSA-1433557
FCGR activation R-HSA-2029481
Leishmania infection R-HSA-9658195
Parasite infection R-HSA-9664407
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Axon guidance R-HSA-422475
Costimulation by the CD28 family R-HSA-388841
Hemostasis R-HSA-109582
Disease R-HSA-1643685
EPH-Ephrin signaling R-HSA-2682334
EPHB-mediated forward signaling R-HSA-3928662
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Infectious disease R-HSA-5663205
Leishmania phagocytosis R-HSA-9664417
FCGR3A-mediated phagocytosis R-HSA-9664422
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Gene expression (Transcription) R-HSA-74160
Regulation of signaling by CBL R-HSA-912631
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
Signaling by KIT in disease R-HSA-9669938
EPHA-mediated growth cone collapse R-HSA-3928663
Signaling by ERBB2 R-HSA-1227986
Cytokine Signaling in Immune system R-HSA-1280215
CTLA4 inhibitory signaling R-HSA-389513
Transcriptional regulation by RUNX2 R-HSA-8878166
Signal Transduction R-HSA-162582
Cell surface interactions at the vascular wall R-HSA-202733
Adaptive Immune System R-HSA-1280218
RUNX2 regulates bone development R-HSA-8941326
Leishmania parasite growth and survival R-HSA-9664433
EPH-ephrin mediated repulsion of cells R-HSA-3928665
PECAM1 interactions R-HSA-210990
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hemostasis R-HSA-109582
EPHB-mediated forward signaling R-HSA-3928662
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX2 R-HSA-8878166
RNA Polymerase II Transcription R-HSA-73857
Regulation of KIT signaling R-HSA-1433559
Signaling by SCF-KIT R-HSA-1433557
Innate Immune System R-HSA-168249
Axon guidance R-HSA-422475
Leishmania parasite growth and survival R-HSA-9664433
Regulation of signaling by CBL R-HSA-912631
RUNX2 regulates bone development R-HSA-8941326
CD28 co-stimulation R-HSA-389356
FCGR3A-mediated phagocytosis R-HSA-9664422
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
CTLA4 inhibitory signaling R-HSA-389513
EPH-Ephrin signaling R-HSA-2682334
Infectious disease R-HSA-5663205
FCGR3A-mediated IL10 synthesis R-HSA-9664323
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Generic Transcription Pathway R-HSA-212436
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
FCGR activation R-HSA-2029481
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by ERBB2 R-HSA-1227986
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Adaptive Immune System R-HSA-1280218
Leishmania phagocytosis R-HSA-9664417
EPHA-mediated growth cone collapse R-HSA-3928663
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Costimulation by the CD28 family R-HSA-388841
Signaling by KIT in disease R-HSA-9669938
Signaling by Interleukins R-HSA-449147
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Nervous system development R-HSA-9675108
Leishmania infection R-HSA-9658195
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Gene expression (Transcription) R-HSA-74160
Parasite infection R-HSA-9664407
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Signaling by Interleukins R-HSA-449147
EPHA-mediated growth cone collapse R-HSA-3928663
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by KIT in disease R-HSA-9669938
Costimulation by the CD28 family R-HSA-388841
Regulation of KIT signaling R-HSA-1433559
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Developmental Biology R-HSA-1266738
Leishmania phagocytosis R-HSA-9664417
Axon guidance R-HSA-422475
RNA Polymerase II Transcription R-HSA-73857
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RUNX2 regulates bone development R-HSA-8941326
Hemostasis R-HSA-109582
Nervous system development R-HSA-9675108
PECAM1 interactions R-HSA-210990
CTLA4 inhibitory signaling R-HSA-389513
Signaling by ERBB2 R-HSA-1227986
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Gene expression (Transcription) R-HSA-74160
Infectious disease R-HSA-5663205
EPH-Ephrin signaling R-HSA-2682334
FCGR activation R-HSA-2029481
Cell surface interactions at the vascular wall R-HSA-202733
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX2 R-HSA-8878166
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Cytokine Signaling in Immune system R-HSA-1280215
Leishmania infection R-HSA-9658195
Generic Transcription Pathway R-HSA-212436
CD28 co-stimulation R-HSA-389356
Parasite infection R-HSA-9664407
EPHB-mediated forward signaling R-HSA-3928662
EPH-ephrin mediated repulsion of cells R-HSA-3928665
FCGR3A-mediated phagocytosis R-HSA-9664422
Immune System R-HSA-168256
Leishmania parasite growth and survival R-HSA-9664433
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Regulation of signaling by CBL R-HSA-912631
RUNX2 regulates osteoblast differentiation R-HSA-8940973
FCGR3A-mediated phagocytosis R-HSA-9664422
Signal Transduction R-HSA-162582
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Cell surface interactions at the vascular wall R-HSA-202733
Leishmania phagocytosis R-HSA-9664417
CTLA4 inhibitory signaling R-HSA-389513
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Regulation of signaling by CBL R-HSA-912631
Nervous system development R-HSA-9675108
Leishmania parasite growth and survival R-HSA-9664433
Signaling by SCF-KIT R-HSA-1433557
Gene expression (Transcription) R-HSA-74160
PECAM1 interactions R-HSA-210990
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Immune System R-HSA-168256
Hemostasis R-HSA-109582
Signaling by KIT in disease R-HSA-9669938
EPHB-mediated forward signaling R-HSA-3928662
Adaptive Immune System R-HSA-1280218
RNA Polymerase II Transcription R-HSA-73857
EPHA-mediated growth cone collapse R-HSA-3928663
Leishmania infection R-HSA-9658195
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Regulation of KIT signaling R-HSA-1433559
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Signaling by ERBB2 R-HSA-1227986
RUNX2 regulates bone development R-HSA-8941326
FCGR activation R-HSA-2029481
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Generic Transcription Pathway R-HSA-212436
Signaling by Interleukins R-HSA-449147
Disease R-HSA-1643685
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
EPH-ephrin mediated repulsion of cells R-HSA-3928665
CD28 co-stimulation R-HSA-389356
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Parasite infection R-HSA-9664407
Costimulation by the CD28 family R-HSA-388841
EPH-Ephrin signaling R-HSA-2682334
Innate Immune System R-HSA-168249

Expression Atlas ENSG00000176105
NCBI gene (formerly Entrezgene) 7525
GeneCards 12841
HGNC Symbol HGNC:12841
MIM gene 164880
UniProtKB Gene Name P07947
WikiGene 7525