Gene: PLK4
Ensembl ID : ENSG00000142731
Description: polo like kinase 4
Gene Synonyms: SAK,STK18
2 APIs:
215 Possible Orthologues:

G2/M Transition R-HSA-69275
Cilium Assembly R-HSA-5617833
Loss of Nlp from mitotic centrosomes R-HSA-380259
Centrosome maturation R-HSA-380287
Cell Cycle R-HSA-1640170
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Organelle biogenesis and maintenance R-HSA-1852241
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
M Phase R-HSA-68886
AURKA Activation by TPX2 R-HSA-8854518
Mitotic Prometaphase R-HSA-68877
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
M Phase R-HSA-68886
Cilium Assembly R-HSA-5617833
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Centrosome maturation R-HSA-380287
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Mitotic Prometaphase R-HSA-68877
Mitotic G2-G2/M phases R-HSA-453274
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
AURKA Activation by TPX2 R-HSA-8854518
Cell Cycle R-HSA-1640170
Loss of Nlp from mitotic centrosomes R-HSA-380259
Organelle biogenesis and maintenance R-HSA-1852241
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
G2/M Transition R-HSA-69275
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Cell Cycle R-HSA-1640170
Centrosome maturation R-HSA-380287
Cell Cycle, Mitotic R-HSA-69278
AURKA Activation by TPX2 R-HSA-8854518
Organelle biogenesis and maintenance R-HSA-1852241
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Prometaphase R-HSA-68877
Cilium Assembly R-HSA-5617833
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
M Phase R-HSA-68886
Loss of Nlp from mitotic centrosomes R-HSA-380259
Organelle biogenesis and maintenance R-HSA-1852241
Cell Cycle R-HSA-1640170
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Cell Cycle, Mitotic R-HSA-69278
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Cilium Assembly R-HSA-5617833
Loss of Nlp from mitotic centrosomes R-HSA-380259
Mitotic G2-G2/M phases R-HSA-453274
AURKA Activation by TPX2 R-HSA-8854518
Centrosome maturation R-HSA-380287
M Phase R-HSA-68886
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
G2/M Transition R-HSA-69275
Mitotic Prometaphase R-HSA-68877
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Mitotic Prometaphase R-HSA-68877
Loss of Nlp from mitotic centrosomes R-HSA-380259
Cell Cycle, Mitotic R-HSA-69278
Organelle biogenesis and maintenance R-HSA-1852241
M Phase R-HSA-68886
Cilium Assembly R-HSA-5617833
Centrosome maturation R-HSA-380287
G2/M Transition R-HSA-69275
AURKA Activation by TPX2 R-HSA-8854518
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle R-HSA-1640170
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Prometaphase R-HSA-68877
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Centrosome maturation R-HSA-380287
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
M Phase R-HSA-68886
AURKA Activation by TPX2 R-HSA-8854518
Loss of Nlp from mitotic centrosomes R-HSA-380259
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Organelle biogenesis and maintenance R-HSA-1852241
Cell Cycle R-HSA-1640170
Cilium Assembly R-HSA-5617833
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Organelle biogenesis and maintenance R-HSA-1852241
Cilium Assembly R-HSA-5617833
Mitotic Prometaphase R-HSA-68877
Cell Cycle R-HSA-1640170
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
M Phase R-HSA-68886
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Cell Cycle, Mitotic R-HSA-69278
G2/M Transition R-HSA-69275
AURKA Activation by TPX2 R-HSA-8854518
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Loss of Nlp from mitotic centrosomes R-HSA-380259
Centrosome maturation R-HSA-380287
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Mitotic G2-G2/M phases R-HSA-453274
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
G2/M Transition R-HSA-69275
AURKA Activation by TPX2 R-HSA-8854518
Loss of Nlp from mitotic centrosomes R-HSA-380259
Cell Cycle, Mitotic R-HSA-69278
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Cilium Assembly R-HSA-5617833
Mitotic Prometaphase R-HSA-68877
Organelle biogenesis and maintenance R-HSA-1852241
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Centrosome maturation R-HSA-380287
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
Cell Cycle R-HSA-1640170
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Cilium Assembly R-HSA-5617833
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Cell Cycle R-HSA-1640170
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
M Phase R-HSA-68886
G2/M Transition R-HSA-69275
Loss of Nlp from mitotic centrosomes R-HSA-380259
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
AURKA Activation by TPX2 R-HSA-8854518
Organelle biogenesis and maintenance R-HSA-1852241
Centrosome maturation R-HSA-380287
G2/M Transition R-HSA-69275
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Mitotic Prometaphase R-HSA-68877
Cell Cycle, Mitotic R-HSA-69278
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Loss of Nlp from mitotic centrosomes R-HSA-380259
Mitotic G2-G2/M phases R-HSA-453274
Centrosome maturation R-HSA-380287
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Organelle biogenesis and maintenance R-HSA-1852241
Cilium Assembly R-HSA-5617833
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Cell Cycle R-HSA-1640170
M Phase R-HSA-68886
AURKA Activation by TPX2 R-HSA-8854518
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Anchoring of the basal body to the plasma membrane R-HSA-5620912
AURKA Activation by TPX2 R-HSA-8854518
Cell Cycle, Mitotic R-HSA-69278
Centrosome maturation R-HSA-380287
Organelle biogenesis and maintenance R-HSA-1852241
Loss of Nlp from mitotic centrosomes R-HSA-380259
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
M Phase R-HSA-68886
Cilium Assembly R-HSA-5617833
Mitotic Prometaphase R-HSA-68877
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Cell Cycle R-HSA-1640170
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Mitotic G2-G2/M phases R-HSA-453274
G2/M Transition R-HSA-69275

Expression Atlas ENSG00000142731
NCBI gene (formerly Entrezgene) 10733
GeneCards 11397
HGNC Symbol HGNC:11397
MIM gene 605031
MIM morbid 616171
UniProtKB Gene Name O00444
WikiGene 10733
Gene: CDK1
Ensembl ID : ENSG00000170312
Description: cyclin dependent kinase 1
Gene Synonyms: CDC2,CDC28A
9 APIs:
241 Possible Orthologues:

Mitotic Prophase R-HSA-68875
Gene expression (Transcription) R-HSA-74160
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
Mitotic G1 phase and G1/S transition R-HSA-453279
Deubiquitination R-HSA-5688426
G2/M Checkpoints R-HSA-69481
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Regulation of TP53 Degradation R-HSA-6804757
RNA Polymerase II Transcription R-HSA-73857
MAPK6/MAPK4 signaling R-HSA-5687128
Condensation of Prometaphase Chromosomes R-HSA-2514853
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Resolution of Sister Chromatid Cohesion R-HSA-2500257
E2F mediated regulation of DNA replication R-HSA-113510
Mitotic Prophase R-HSA-68875
Transcriptional Regulation by TP53 R-HSA-3700989
Ovarian tumor domain proteases R-HSA-5689896
G2/M Transition R-HSA-69275
Nuclear Envelope Breakdown R-HSA-2980766
G1/S-Specific Transcription R-HSA-69205
Phosphorylation of Emi1 R-HSA-176417
G2/M DNA replication checkpoint R-HSA-69478
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Anchoring of the basal body to the plasma membrane R-HSA-5620912
M Phase R-HSA-68886
Phosphorylation of the APC/C R-HSA-176412
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Cell Cycle, Mitotic R-HSA-69278
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Mitotic Prometaphase R-HSA-68877
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Gene expression (Transcription) R-HSA-74160
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
G1/S Transition R-HSA-69206
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Cilium Assembly R-HSA-5617833
Mitotic Anaphase R-HSA-68882
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
MAPK family signaling cascades R-HSA-5683057
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
MAPK3 (ERK1) activation R-HSA-110056
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle Checkpoints R-HSA-69620
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G2/M DNA damage checkpoint R-HSA-69473
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
MASTL Facilitates Mitotic Progression R-HSA-2465910
Centrosome maturation R-HSA-380287
Regulation of TP53 Activity R-HSA-5633007
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Condensation of Prophase Chromosomes R-HSA-2299718
RAF-independent MAPK1/3 activation R-HSA-112409
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Cell Cycle R-HSA-1640170
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
AURKA Activation by TPX2 R-HSA-8854518
Loss of Nlp from mitotic centrosomes R-HSA-380259
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G0 and Early G1 R-HSA-1538133
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic Metaphase and Anaphase R-HSA-2555396
Organelle biogenesis and maintenance R-HSA-1852241
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Regulation of mitotic cell cycle R-HSA-453276
MAPK3 (ERK1) activation R-HSA-110056
AURKA Activation by TPX2 R-HSA-8854518
G1/S Transition R-HSA-69206
Mitotic Anaphase R-HSA-68882
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Expression and Degradation R-HSA-6806003
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Loss of Nlp from mitotic centrosomes R-HSA-380259
Phosphorylation of Emi1 R-HSA-176417
Nuclear Envelope Breakdown R-HSA-2980766
G0 and Early G1 R-HSA-1538133
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
Mitotic Metaphase and Anaphase R-HSA-2555396
Ovarian tumor domain proteases R-HSA-5689896
Depolymerisation of the Nuclear Lamina R-HSA-4419969
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Mitotic G1 phase and G1/S transition R-HSA-453279
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
G2/M DNA replication checkpoint R-HSA-69478
Organelle biogenesis and maintenance R-HSA-1852241
Mitotic G2-G2/M phases R-HSA-453274
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
E2F mediated regulation of DNA replication R-HSA-113510
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
G2/M DNA damage checkpoint R-HSA-69473
MAPK1/MAPK3 signaling R-HSA-5684996
Generic Transcription Pathway R-HSA-212436
Mitotic Prophase R-HSA-68875
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Gene expression (Transcription) R-HSA-74160
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Phosphorylation of the APC/C R-HSA-176412
Regulation of TP53 Degradation R-HSA-6804757
Cilium Assembly R-HSA-5617833
Centrosome maturation R-HSA-380287
Deubiquitination R-HSA-5688426
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G2/M Checkpoints R-HSA-69481
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
M Phase R-HSA-68886
Transcriptional Regulation by TP53 R-HSA-3700989
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Cell Cycle R-HSA-1640170
Condensation of Prometaphase Chromosomes R-HSA-2514853
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Transcriptional regulation by RUNX2 R-HSA-8878166
MASTL Facilitates Mitotic Progression R-HSA-2465910
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Regulation of TP53 Activity R-HSA-5633007
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Cell Cycle Checkpoints R-HSA-69620
Metabolism of proteins R-HSA-392499
MAPK family signaling cascades R-HSA-5683057
Condensation of Prophase Chromosomes R-HSA-2299718
G1/S-Specific Transcription R-HSA-69205
RAF-independent MAPK1/3 activation R-HSA-112409
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mitotic cell cycle R-HSA-453276
Post-translational protein modification R-HSA-597592
Ovarian tumor domain proteases R-HSA-5689896
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nuclear Envelope Breakdown R-HSA-2980766
Condensation of Prometaphase Chromosomes R-HSA-2514853
Loss of Nlp from mitotic centrosomes R-HSA-380259
Deubiquitination R-HSA-5688426
AURKA Activation by TPX2 R-HSA-8854518
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Depolymerisation of the Nuclear Lamina R-HSA-4419969
RAF-independent MAPK1/3 activation R-HSA-112409
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of proteins R-HSA-392499
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Regulation of TP53 Expression and Degradation R-HSA-6806003
Mitotic Prometaphase R-HSA-68877
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
M Phase R-HSA-68886
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic Anaphase R-HSA-68882
G2/M Checkpoints R-HSA-69481
G0 and Early G1 R-HSA-1538133
G1/S Transition R-HSA-69206
Mitotic G2-G2/M phases R-HSA-453274
Anchoring of the basal body to the plasma membrane R-HSA-5620912
E2F mediated regulation of DNA replication R-HSA-113510
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Cell Cycle, Mitotic R-HSA-69278
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Degradation R-HSA-6804757
Transcriptional Regulation by TP53 R-HSA-3700989
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Mitotic Metaphase and Anaphase R-HSA-2555396
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
G2/M DNA damage checkpoint R-HSA-69473
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
MASTL Facilitates Mitotic Progression R-HSA-2465910
Signal Transduction R-HSA-162582
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Organelle biogenesis and maintenance R-HSA-1852241
G2/M DNA replication checkpoint R-HSA-69478
Phosphorylation of the APC/C R-HSA-176412
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Regulation of TP53 Activity R-HSA-5633007
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
Centrosome maturation R-HSA-380287
Phosphorylation of Emi1 R-HSA-176417
Condensation of Prophase Chromosomes R-HSA-2299718
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
MAPK3 (ERK1) activation R-HSA-110056
MAPK family signaling cascades R-HSA-5683057
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Cilium Assembly R-HSA-5617833
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S-Specific Transcription R-HSA-69205
G2/M Transition R-HSA-69275
Cell Cycle Checkpoints R-HSA-69620
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of mitotic cell cycle R-HSA-453276
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
MAPK3 (ERK1) activation R-HSA-110056
Cilium Assembly R-HSA-5617833
G1/S Transition R-HSA-69206
Gene expression (Transcription) R-HSA-74160
Condensation of Prophase Chromosomes R-HSA-2299718
AURKA Activation by TPX2 R-HSA-8854518
Resolution of Sister Chromatid Cohesion R-HSA-2500257
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
Nuclear Envelope Breakdown R-HSA-2980766
Regulation of TP53 Degradation R-HSA-6804757
Centrosome maturation R-HSA-380287
Deubiquitination R-HSA-5688426
RNA Polymerase II Transcription R-HSA-73857
RAF-independent MAPK1/3 activation R-HSA-112409
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle Checkpoints R-HSA-69620
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Phosphorylation of Emi1 R-HSA-176417
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of TP53 Expression and Degradation R-HSA-6806003
G2/M Checkpoints R-HSA-69481
MAPK1/MAPK3 signaling R-HSA-5684996
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Mitotic Metaphase and Anaphase R-HSA-2555396
Transcriptional regulation by RUNX2 R-HSA-8878166
Phosphorylation of the APC/C R-HSA-176412
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Organelle biogenesis and maintenance R-HSA-1852241
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Loss of Nlp from mitotic centrosomes R-HSA-380259
Post-translational protein modification R-HSA-597592
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle R-HSA-1640170
Mitotic Anaphase R-HSA-68882
Mitotic Prophase R-HSA-68875
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
G2/M DNA damage checkpoint R-HSA-69473
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
G1/S-Specific Transcription R-HSA-69205
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Condensation of Prometaphase Chromosomes R-HSA-2514853
Ovarian tumor domain proteases R-HSA-5689896
Mitotic Prometaphase R-HSA-68877
Regulation of TP53 Activity R-HSA-5633007
MAPK family signaling cascades R-HSA-5683057
Mitotic G2-G2/M phases R-HSA-453274
Nuclear Envelope (NE) Reassembly R-HSA-2995410
MASTL Facilitates Mitotic Progression R-HSA-2465910
G2/M Transition R-HSA-69275
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Regulation of mitotic cell cycle R-HSA-453276
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional Regulation by TP53 R-HSA-3700989
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
G0 and Early G1 R-HSA-1538133
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic G1 phase and G1/S transition R-HSA-453279
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
E2F mediated regulation of DNA replication R-HSA-113510
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
G2/M DNA replication checkpoint R-HSA-69478
Regulation of TP53 Activity R-HSA-5633007
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Deubiquitination R-HSA-5688426
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Gene expression (Transcription) R-HSA-74160
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of TP53 Degradation R-HSA-6804757
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
RAF-independent MAPK1/3 activation R-HSA-112409
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Generic Transcription Pathway R-HSA-212436
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Mitotic G2-G2/M phases R-HSA-453274
G2/M DNA damage checkpoint R-HSA-69473
Cell Cycle R-HSA-1640170
Regulation of TP53 Expression and Degradation R-HSA-6806003
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Cilium Assembly R-HSA-5617833
Loss of Nlp from mitotic centrosomes R-HSA-380259
M Phase R-HSA-68886
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Metabolism of proteins R-HSA-392499
Phosphorylation of Emi1 R-HSA-176417
Organelle biogenesis and maintenance R-HSA-1852241
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Nuclear Envelope Breakdown R-HSA-2980766
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
MAPK3 (ERK1) activation R-HSA-110056
Depolymerisation of the Nuclear Lamina R-HSA-4419969
MASTL Facilitates Mitotic Progression R-HSA-2465910
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
E2F mediated regulation of DNA replication R-HSA-113510
MAPK family signaling cascades R-HSA-5683057
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Ovarian tumor domain proteases R-HSA-5689896
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Transcriptional regulation by RUNX2 R-HSA-8878166
AURKA Activation by TPX2 R-HSA-8854518
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
Condensation of Prophase Chromosomes R-HSA-2299718
G2/M Checkpoints R-HSA-69481
Transcriptional Regulation by TP53 R-HSA-3700989
G0 and Early G1 R-HSA-1538133
Mitotic Prophase R-HSA-68875
Signal Transduction R-HSA-162582
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic Prometaphase R-HSA-68877
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
G2/M DNA replication checkpoint R-HSA-69478
G1/S-Specific Transcription R-HSA-69205
Condensation of Prometaphase Chromosomes R-HSA-2514853
Centrosome maturation R-HSA-380287
G2/M Transition R-HSA-69275
MAPK6/MAPK4 signaling R-HSA-5687128
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Anaphase R-HSA-68882
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Post-translational protein modification R-HSA-597592
Phosphorylation of the APC/C R-HSA-176412
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Cell Cycle, Mitotic R-HSA-69278
Regulation of TP53 Degradation R-HSA-6804757
Cell Cycle, Mitotic R-HSA-69278
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Mitotic Prometaphase R-HSA-68877
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
RAF-independent MAPK1/3 activation R-HSA-112409
MAPK6/MAPK4 signaling R-HSA-5687128
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Phosphorylation of the APC/C R-HSA-176412
Regulation of TP53 Expression and Degradation R-HSA-6806003
Nuclear Envelope (NE) Reassembly R-HSA-2995410
AURKA Activation by TPX2 R-HSA-8854518
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Regulation of mitotic cell cycle R-HSA-453276
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Organelle biogenesis and maintenance R-HSA-1852241
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
MASTL Facilitates Mitotic Progression R-HSA-2465910
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Centrosome maturation R-HSA-380287
Mitotic Prophase R-HSA-68875
Cell Cycle Checkpoints R-HSA-69620
G2/M DNA replication checkpoint R-HSA-69478
Metabolism of proteins R-HSA-392499
G2/M Transition R-HSA-69275
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Nuclear Envelope Breakdown R-HSA-2980766
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Condensation of Prophase Chromosomes R-HSA-2299718
Regulation of TP53 Activity R-HSA-5633007
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Deubiquitination R-HSA-5688426
G2/M Checkpoints R-HSA-69481
Mitotic G2-G2/M phases R-HSA-453274
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
MAPK family signaling cascades R-HSA-5683057
G1/S-Specific Transcription R-HSA-69205
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Cell Cycle R-HSA-1640170
Condensation of Prometaphase Chromosomes R-HSA-2514853
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Transcriptional Regulation by TP53 R-HSA-3700989
G0 and Early G1 R-HSA-1538133
Cilium Assembly R-HSA-5617833
MAPK3 (ERK1) activation R-HSA-110056
Post-translational protein modification R-HSA-597592
G1/S Transition R-HSA-69206
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
M Phase R-HSA-68886
Loss of Nlp from mitotic centrosomes R-HSA-380259
G2/M DNA damage checkpoint R-HSA-69473
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
E2F mediated regulation of DNA replication R-HSA-113510
Gene expression (Transcription) R-HSA-74160
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Metaphase and Anaphase R-HSA-2555396
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX2 R-HSA-8878166
Ovarian tumor domain proteases R-HSA-5689896
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic G1 phase and G1/S transition R-HSA-453279
Phosphorylation of Emi1 R-HSA-176417
MAPK1/MAPK3 signaling R-HSA-5684996
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Mitotic Anaphase R-HSA-68882
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX2 R-HSA-8878166
G2/M DNA damage checkpoint R-HSA-69473
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Transcriptional Regulation by TP53 R-HSA-3700989
Cell Cycle Checkpoints R-HSA-69620
G1/S-Specific Transcription R-HSA-69205
Metabolism of proteins R-HSA-392499
Phosphorylation of the APC/C R-HSA-176412
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cilium Assembly R-HSA-5617833
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Mitotic G2-G2/M phases R-HSA-453274
Condensation of Prophase Chromosomes R-HSA-2299718
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Centrosome maturation R-HSA-380287
Cell Cycle, Mitotic R-HSA-69278
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Generic Transcription Pathway R-HSA-212436
Mitotic Prophase R-HSA-68875
Cell Cycle R-HSA-1640170
Nuclear Envelope (NE) Reassembly R-HSA-2995410
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Depolymerisation of the Nuclear Lamina R-HSA-4419969
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Nuclear Envelope Breakdown R-HSA-2980766
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
RNA Polymerase II Transcription R-HSA-73857
G2/M Transition R-HSA-69275
E2F mediated regulation of DNA replication R-HSA-113510
Mitotic Anaphase R-HSA-68882
Organelle biogenesis and maintenance R-HSA-1852241
Loss of Nlp from mitotic centrosomes R-HSA-380259
Gene expression (Transcription) R-HSA-74160
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
G2/M DNA replication checkpoint R-HSA-69478
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Ovarian tumor domain proteases R-HSA-5689896
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
MASTL Facilitates Mitotic Progression R-HSA-2465910
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Signal Transduction R-HSA-162582
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of TP53 Activity R-HSA-5633007
RAF-independent MAPK1/3 activation R-HSA-112409
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
Condensation of Prometaphase Chromosomes R-HSA-2514853
Regulation of TP53 Degradation R-HSA-6804757
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
G0 and Early G1 R-HSA-1538133
Mitotic Prometaphase R-HSA-68877
Post-translational protein modification R-HSA-597592
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Phosphorylation of Emi1 R-HSA-176417
Deubiquitination R-HSA-5688426
G1/S Transition R-HSA-69206
MAPK3 (ERK1) activation R-HSA-110056
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Regulation of mitotic cell cycle R-HSA-453276
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK1/MAPK3 signaling R-HSA-5684996
AURKA Activation by TPX2 R-HSA-8854518
G2/M DNA damage checkpoint R-HSA-69473
G2/M Checkpoints R-HSA-69481
G0 and Early G1 R-HSA-1538133
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Cell Cycle Checkpoints R-HSA-69620
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Deubiquitination R-HSA-5688426
Transcriptional Regulation by TP53 R-HSA-3700989
Depolymerisation of the Nuclear Lamina R-HSA-4419969
G2/M DNA replication checkpoint R-HSA-69478
Cilium Assembly R-HSA-5617833
Regulation of TP53 Expression and Degradation R-HSA-6806003
Mitotic Prometaphase R-HSA-68877
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Condensation of Prophase Chromosomes R-HSA-2299718
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Metabolism of proteins R-HSA-392499
RAF-independent MAPK1/3 activation R-HSA-112409
Regulation of TP53 Degradation R-HSA-6804757
Mitotic Prophase R-HSA-68875
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Cell Cycle, Mitotic R-HSA-69278
Mitotic Metaphase and Anaphase R-HSA-2555396
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Mitotic G1 phase and G1/S transition R-HSA-453279
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
G1/S Transition R-HSA-69206
Nuclear Envelope Breakdown R-HSA-2980766
MASTL Facilitates Mitotic Progression R-HSA-2465910
Loss of Nlp from mitotic centrosomes R-HSA-380259
Phosphorylation of the APC/C R-HSA-176412
G2/M Transition R-HSA-69275
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
E2F mediated regulation of DNA replication R-HSA-113510
Regulation of mitotic cell cycle R-HSA-453276
RNA Polymerase II Transcription R-HSA-73857
AURKA Activation by TPX2 R-HSA-8854518
Cell Cycle R-HSA-1640170
Organelle biogenesis and maintenance R-HSA-1852241
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK family signaling cascades R-HSA-5683057
G1/S-Specific Transcription R-HSA-69205
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Centrosome maturation R-HSA-380287
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ovarian tumor domain proteases R-HSA-5689896
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Anaphase R-HSA-68882
Post-translational protein modification R-HSA-597592
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Mitotic G2-G2/M phases R-HSA-453274
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Condensation of Prometaphase Chromosomes R-HSA-2514853
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Phosphorylation of Emi1 R-HSA-176417
MAPK3 (ERK1) activation R-HSA-110056
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Regulation of TP53 Activity R-HSA-5633007
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
MAPK1/MAPK3 signaling R-HSA-5684996
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Transcriptional regulation by RUNX2 R-HSA-8878166
Signal Transduction R-HSA-162582
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulation of mitotic cell cycle R-HSA-453276
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
RNA Polymerase II Transcription R-HSA-73857
Mitotic Prometaphase R-HSA-68877
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Deubiquitination R-HSA-5688426
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
AURKA Activation by TPX2 R-HSA-8854518
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
Cell Cycle Checkpoints R-HSA-69620
G1/S Transition R-HSA-69206
Signal Transduction R-HSA-162582
RAF-independent MAPK1/3 activation R-HSA-112409
M Phase R-HSA-68886
E2F mediated regulation of DNA replication R-HSA-113510
Mitotic Prophase R-HSA-68875
Regulation of TP53 Expression and Degradation R-HSA-6806003
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Degradation R-HSA-6804757
MAPK3 (ERK1) activation R-HSA-110056
G2/M DNA replication checkpoint R-HSA-69478
MAPK family signaling cascades R-HSA-5683057
Mitotic G2-G2/M phases R-HSA-453274
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Mitotic Anaphase R-HSA-68882
Regulation of TP53 Activity R-HSA-5633007
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cilium Assembly R-HSA-5617833
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Post-translational protein modification R-HSA-597592
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Loss of Nlp from mitotic centrosomes R-HSA-380259
G2/M Transition R-HSA-69275
Nuclear Envelope (NE) Reassembly R-HSA-2995410
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Phosphorylation of the APC/C R-HSA-176412
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Anchoring of the basal body to the plasma membrane R-HSA-5620912
MAPK6/MAPK4 signaling R-HSA-5687128
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Phosphorylation of Emi1 R-HSA-176417
Transcriptional Regulation by TP53 R-HSA-3700989
MASTL Facilitates Mitotic Progression R-HSA-2465910
G0 and Early G1 R-HSA-1538133
Transcriptional regulation by RUNX2 R-HSA-8878166
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Resolution of Sister Chromatid Cohesion R-HSA-2500257
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
G1/S-Specific Transcription R-HSA-69205
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Centrosome maturation R-HSA-380287
Cell Cycle, Mitotic R-HSA-69278
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Nuclear Envelope Breakdown R-HSA-2980766
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Metabolism of proteins R-HSA-392499
G2/M Checkpoints R-HSA-69481
Organelle biogenesis and maintenance R-HSA-1852241
Condensation of Prometaphase Chromosomes R-HSA-2514853
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Condensation of Prophase Chromosomes R-HSA-2299718
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M DNA damage checkpoint R-HSA-69473
Ovarian tumor domain proteases R-HSA-5689896
MAPK1/MAPK3 signaling R-HSA-5684996
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Centrosome maturation R-HSA-380287
Metabolism of proteins R-HSA-392499
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Nuclear Envelope (NE) Reassembly R-HSA-2995410
Nuclear Envelope Breakdown R-HSA-2980766
AURKA Activation by TPX2 R-HSA-8854518
Cell Cycle R-HSA-1640170
Loss of Nlp from mitotic centrosomes R-HSA-380259
MASTL Facilitates Mitotic Progression R-HSA-2465910
Depolymerisation of the Nuclear Lamina R-HSA-4419969
Mitotic G2-G2/M phases R-HSA-453274
G2/M Checkpoints R-HSA-69481
Ovarian tumor domain proteases R-HSA-5689896
Post-translational protein modification R-HSA-597592
MAPK6/MAPK4 signaling R-HSA-5687128
Cilium Assembly R-HSA-5617833
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
G2/M DNA replication checkpoint R-HSA-69478
Resolution of Sister Chromatid Cohesion R-HSA-2500257
G0 and Early G1 R-HSA-1538133
Mitotic Prophase R-HSA-68875
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of TP53 Activity R-HSA-5633007
M Phase R-HSA-68886
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Prometaphase R-HSA-68877
Signal Transduction R-HSA-162582
Condensation of Prometaphase Chromosomes R-HSA-2514853
Phosphorylation of the APC/C R-HSA-176412
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
RAF-independent MAPK1/3 activation R-HSA-112409
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Deubiquitination R-HSA-5688426
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
Organelle biogenesis and maintenance R-HSA-1852241
G1/S-Specific Transcription R-HSA-69205
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Mitotic G1 phase and G1/S transition R-HSA-453279
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulation of TP53 Expression and Degradation R-HSA-6806003
G2/M DNA damage checkpoint R-HSA-69473
MAPK family signaling cascades R-HSA-5683057
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic Anaphase R-HSA-68882
RNA Polymerase II Transcription R-HSA-73857
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle Checkpoints R-HSA-69620
MAPK3 (ERK1) activation R-HSA-110056
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of TP53 Degradation R-HSA-6804757
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Transcriptional Regulation by TP53 R-HSA-3700989
G1/S Transition R-HSA-69206
Condensation of Prophase Chromosomes R-HSA-2299718
Phosphorylation of Emi1 R-HSA-176417
E2F mediated regulation of DNA replication R-HSA-113510
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of mitotic cell cycle R-HSA-453276
G2/M Transition R-HSA-69275
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Resolution of Sister Chromatid Cohesion R-HSA-2500257
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383
Organelle biogenesis and maintenance R-HSA-1852241
MAPK3 (ERK1) activation R-HSA-110056
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of TP53 Degradation R-HSA-6804757
Ovarian tumor domain proteases R-HSA-5689896
RAF-independent MAPK1/3 activation R-HSA-112409
G0 and Early G1 R-HSA-1538133
G2/M DNA replication checkpoint R-HSA-69478
Signal Transduction R-HSA-162582
Nuclear Envelope (NE) Reassembly R-HSA-2995410
E2F mediated regulation of DNA replication R-HSA-113510
G1/S Transition R-HSA-69206
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Depolymerisation of the Nuclear Lamina R-HSA-4419969
G1/S-Specific Transcription R-HSA-69205
M Phase R-HSA-68886
Post-translational protein modification R-HSA-597592
Cell Cycle R-HSA-1640170
Cell Cycle Checkpoints R-HSA-69620
G2/M Transition R-HSA-69275
Regulation of TP53 Expression and Degradation R-HSA-6806003
Mitotic Anaphase R-HSA-68882
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Deubiquitination R-HSA-5688426
Condensation of Prophase Chromosomes R-HSA-2299718
Regulation of TP53 Activity R-HSA-5633007
Phosphorylation of the APC/C R-HSA-176412
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300
Mitotic G1 phase and G1/S transition R-HSA-453279
Condensation of Prometaphase Chromosomes R-HSA-2514853
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Loss of Nlp from mitotic centrosomes R-HSA-380259
Mitotic Prometaphase R-HSA-68877
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035
Centrosome maturation R-HSA-380287
Regulation of mitotic cell cycle R-HSA-453276
Cilium Assembly R-HSA-5617833
MAPK1/MAPK3 signaling R-HSA-5684996
MASTL Facilitates Mitotic Progression R-HSA-2465910
Transcriptional Regulation by TP53 R-HSA-3700989
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
MAPK6/MAPK4 signaling R-HSA-5687128
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX2 R-HSA-8878166
G2/M DNA damage checkpoint R-HSA-69473
Mitotic G2-G2/M phases R-HSA-453274
Gene expression (Transcription) R-HSA-74160
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes R-HSA-170145
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Mitotic Prophase R-HSA-68875
MAPK family signaling cascades R-HSA-5683057
AURKA Activation by TPX2 R-HSA-8854518
Mitotic Metaphase and Anaphase R-HSA-2555396
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854
Nuclear Envelope Breakdown R-HSA-2980766
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Phosphorylation of Emi1 R-HSA-176417
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507
G2/M Checkpoints R-HSA-69481

Expression Atlas ENSG00000170312
NCBI gene (formerly Entrezgene) 983
GeneCards 1722
HGNC Symbol HGNC:1722
MIM gene 116940
UniProtKB Gene Name P06493
WikiGene 983
Gene: AKT1
Ensembl ID : ENSG00000142208
Description: AKT serine/threonine kinase 1
Gene Synonyms: AKT,PKB,PRKBA,RAC,RAC-ALPHA
16 APIs:
220 Possible Orthologues:

Metabolism R-HSA-1430728
Immune System R-HSA-168256
Cell Cycle R-HSA-1640170
Signaling by GPCR R-HSA-372790
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Gene expression (Transcription) R-HSA-74160
Disease R-HSA-1643685
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular responses to stress R-HSA-2262752
VEGFA-VEGFR2 Pathway R-HSA-4420097
VEGFR2 mediated vascular permeability R-HSA-5218920
eNOS activation R-HSA-203615
CD28 co-stimulation R-HSA-389356
RUNX2 regulates genes involved in cell migration R-HSA-8941332
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
SARS-CoV Infections R-HSA-9679506
AKT phosphorylates targets in the nucleus R-HSA-198693
Metabolism of cofactors R-HSA-8978934
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Vesicle-mediated transport R-HSA-5653656
CD28 dependent PI3K/Akt signaling R-HSA-389357
Integrin signaling R-HSA-354192
Cellular response to chemical stress R-HSA-9711123
AKT-mediated inactivation of FOXO1A R-HSA-211163
Transcriptional Regulation by TP53 R-HSA-3700989
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle R-HSA-1640170
Programmed Cell Death R-HSA-5357801
Signaling by Nuclear Receptors R-HSA-9006931
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FOXO-mediated transcription R-HSA-9614085
Regulation of beta-cell development R-HSA-186712
S Phase R-HSA-69242
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Regulation of TP53 Activity R-HSA-5633007
Hemostasis R-HSA-109582
GPCR downstream signalling R-HSA-388396
Regulation of gene expression in beta cells R-HSA-210745
Generic Transcription Pathway R-HSA-212436
Mitotic G1 phase and G1/S transition R-HSA-453279
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by WNT R-HSA-195721
Regulation of PTEN stability and activity R-HSA-8948751
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Platelet activation, signaling and aggregation R-HSA-76002
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Signaling by GPCR R-HSA-372790
PIP3 activates AKT signaling R-HSA-1257604
Membrane Trafficking R-HSA-199991
Signaling by VEGF R-HSA-194138
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Metabolism of vitamins and cofactors R-HSA-196854
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
FLT3 Signaling R-HSA-9607240
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Extra-nuclear estrogen signaling R-HSA-9009391
SARS-CoV-2 Infection R-HSA-9694516
PTEN Regulation R-HSA-6807070
Signaling by PTK6 R-HSA-8848021
MTOR signalling R-HSA-165159
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
Intrinsic Pathway for Apoptosis R-HSA-109606
TP53 Regulates Metabolic Genes R-HSA-5628897
Rab regulation of trafficking R-HSA-9007101
Infectious disease R-HSA-5663205
Cell Cycle, Mitotic R-HSA-69278
Regulation of TP53 Degradation R-HSA-6804757
Regulation of localization of FOXO transcription factors R-HSA-9614399
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
Metabolism of RNA R-HSA-8953854
Platelet Aggregation (Plug Formation) R-HSA-76009
Activation of BAD and translocation to mitochondria R-HSA-111447
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
TCF dependent signaling in response to WNT R-HSA-201681
PI3K/AKT Signaling in Cancer R-HSA-2219528
Downregulation of ERBB2 signaling R-HSA-8863795
Regulation of TP53 Expression and Degradation R-HSA-6806003
G1/S Transition R-HSA-69206
Signaling by ERBB2 R-HSA-1227986
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
Cyclin E associated events during G1/S transition R-HSA-69202
CTLA4 inhibitory signaling R-HSA-389513
KEAP1-NFE2L2 pathway R-HSA-9755511
Apoptosis R-HSA-109581
ESR-mediated signaling R-HSA-8939211
Costimulation by the CD28 family R-HSA-388841
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
AKT phosphorylates targets in the cytosol R-HSA-198323
Developmental Biology R-HSA-1266738
G-protein beta:gamma signalling R-HSA-397795
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Activation of BH3-only proteins R-HSA-114452
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by NOTCH R-HSA-157118
Apoptosis R-HSA-109581
eNOS activation R-HSA-203615
KEAP1-NFE2L2 pathway R-HSA-9755511
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
PTEN Regulation R-HSA-6807070
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of TP53 Activity through Acetylation R-HSA-6804758
VEGFR2 mediated vascular permeability R-HSA-5218920
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Signaling by Nuclear Receptors R-HSA-9006931
Developmental Biology R-HSA-1266738
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
ESR-mediated signaling R-HSA-8939211
Regulation of TP53 Degradation R-HSA-6804757
Activation of BH3-only proteins R-HSA-114452
Intrinsic Pathway for Apoptosis R-HSA-109606
Rab regulation of trafficking R-HSA-9007101
AKT phosphorylates targets in the cytosol R-HSA-198323
Platelet Aggregation (Plug Formation) R-HSA-76009
Regulation of TP53 Expression and Degradation R-HSA-6806003
FLT3 Signaling R-HSA-9607240
Downregulation of ERBB2 signaling R-HSA-8863795
Costimulation by the CD28 family R-HSA-388841
Signaling by PTK6 R-HSA-8848021
G beta:gamma signalling through PI3Kgamma R-HSA-392451
SARS-CoV Infections R-HSA-9679506
Regulation of localization of FOXO transcription factors R-HSA-9614399
Cell Cycle, Mitotic R-HSA-69278
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
CD28 co-stimulation R-HSA-389356
Negative regulation of the PI3K/AKT network R-HSA-199418
TCF dependent signaling in response to WNT R-HSA-201681
Activation of BAD and translocation to mitochondria R-HSA-111447
PI3K/AKT Signaling in Cancer R-HSA-2219528
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Vesicle-mediated transport R-HSA-5653656
Cellular responses to stress R-HSA-2262752
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
Extra-nuclear estrogen signaling R-HSA-9009391
Integrin signaling R-HSA-354192
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Intracellular signaling by second messengers R-HSA-9006925
Cellular response to chemical stress R-HSA-9711123
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
VEGFA-VEGFR2 Pathway R-HSA-4420097
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Adaptive Immune System R-HSA-1280218
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SARS-CoV-2 Infection R-HSA-9694516
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
Signaling by ERBB2 R-HSA-1227986
FOXO-mediated transcription R-HSA-9614085
Transcriptional regulation by RUNX2 R-HSA-8878166
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Membrane Trafficking R-HSA-199991
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle R-HSA-1640170
Cyclin E associated events during G1/S transition R-HSA-69202
G-protein beta:gamma signalling R-HSA-397795
GPCR downstream signalling R-HSA-388396
Regulation of TP53 Activity R-HSA-5633007
S Phase R-HSA-69242
Signaling by VEGF R-HSA-194138
MTOR signalling R-HSA-165159
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
G1/S Transition R-HSA-69206
Programmed Cell Death R-HSA-5357801
Regulation of gene expression in beta cells R-HSA-210745
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
AKT-mediated inactivation of FOXO1A R-HSA-211163
Hemostasis R-HSA-109582
AKT phosphorylates targets in the nucleus R-HSA-198693
Infectious disease R-HSA-5663205
Metabolism of cofactors R-HSA-8978934
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
RNA Polymerase II Transcription R-HSA-73857
Metabolism of vitamins and cofactors R-HSA-196854
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by NOTCH4 R-HSA-9013694
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional Regulation by TP53 R-HSA-3700989
Cellular responses to stimuli R-HSA-8953897
TP53 Regulates Metabolic Genes R-HSA-5628897
Signaling by Interleukins R-HSA-449147
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Disease R-HSA-1643685
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
Immune System R-HSA-168256
Signaling by GPCR R-HSA-372790
Regulation of beta-cell development R-HSA-186712
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
CTLA4 inhibitory signaling R-HSA-389513
SARS-CoV-2-host interactions R-HSA-9705683
Metabolism of RNA R-HSA-8953854
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Regulation of TP53 Activity R-HSA-5633007
MTOR signalling R-HSA-165159
Signaling by NOTCH R-HSA-157118
Metabolism of vitamins and cofactors R-HSA-196854
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
VEGFR2 mediated vascular permeability R-HSA-5218920
Signal Transduction R-HSA-162582
Activation of BAD and translocation to mitochondria R-HSA-111447
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activation of BH3-only proteins R-HSA-114452
PTEN Regulation R-HSA-6807070
Transcriptional Regulation by TP53 R-HSA-3700989
Intrinsic Pathway for Apoptosis R-HSA-109606
ESR-mediated signaling R-HSA-8939211
Downregulation of ERBB2 signaling R-HSA-8863795
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
AKT phosphorylates targets in the nucleus R-HSA-198693
Signaling by Nuclear Receptors R-HSA-9006931
Adaptive Immune System R-HSA-1280218
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism R-HSA-1430728
CD28 co-stimulation R-HSA-389356
Developmental Biology R-HSA-1266738
Signaling by GPCR R-HSA-372790
Negative regulation of the PI3K/AKT network R-HSA-199418
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
S Phase R-HSA-69242
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stimuli R-HSA-8953897
Metabolism of RNA R-HSA-8953854
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
Regulation of TP53 Degradation R-HSA-6804757
Immune System R-HSA-168256
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
SARS-CoV Infections R-HSA-9679506
G-protein beta:gamma signalling R-HSA-397795
Signaling by WNT R-HSA-195721
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Transcriptional regulation by RUNX2 R-HSA-8878166
Platelet activation, signaling and aggregation R-HSA-76002
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by Interleukins R-HSA-449147
Apoptosis R-HSA-109581
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of beta-cell development R-HSA-186712
Cellular responses to stress R-HSA-2262752
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Hemostasis R-HSA-109582
Cell Cycle, Mitotic R-HSA-69278
GPCR downstream signalling R-HSA-388396
Vesicle-mediated transport R-HSA-5653656
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
FLT3 Signaling R-HSA-9607240
AKT-mediated inactivation of FOXO1A R-HSA-211163
Costimulation by the CD28 family R-HSA-388841
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of gene expression in beta cells R-HSA-210745
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by ERBB2 R-HSA-1227986
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by PTK6 R-HSA-8848021
Mitotic G1 phase and G1/S transition R-HSA-453279
Cytokine Signaling in Immune system R-HSA-1280215
Integrin signaling R-HSA-354192
G1/S Transition R-HSA-69206
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Signaling by NOTCH4 R-HSA-9013694
Membrane Trafficking R-HSA-199991
CTLA4 inhibitory signaling R-HSA-389513
Regulation of PTEN stability and activity R-HSA-8948751
AKT phosphorylates targets in the cytosol R-HSA-198323
CD28 dependent PI3K/Akt signaling R-HSA-389357
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Extra-nuclear estrogen signaling R-HSA-9009391
Generic Transcription Pathway R-HSA-212436
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Intracellular signaling by second messengers R-HSA-9006925
Signaling by VEGF R-HSA-194138
FOXO-mediated transcription R-HSA-9614085
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
eNOS activation R-HSA-203615
SARS-CoV-2 Infection R-HSA-9694516
Platelet Aggregation (Plug Formation) R-HSA-76009
Cellular response to chemical stress R-HSA-9711123
TP53 Regulates Metabolic Genes R-HSA-5628897
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Programmed Cell Death R-HSA-5357801
Metabolism of cofactors R-HSA-8978934
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Regulation of localization of FOXO transcription factors R-HSA-9614399
VEGFA-VEGFR2 Pathway R-HSA-4420097
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Expression and Degradation R-HSA-6806003
Rab regulation of trafficking R-HSA-9007101
PIP3 activates AKT signaling R-HSA-1257604
VEGFA-VEGFR2 Pathway R-HSA-4420097
Vesicle-mediated transport R-HSA-5653656
Regulation of TP53 Activity R-HSA-5633007
TP53 Regulates Metabolic Genes R-HSA-5628897
SARS-CoV Infections R-HSA-9679506
PIP3 activates AKT signaling R-HSA-1257604
PI3K/AKT Signaling in Cancer R-HSA-2219528
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
SARS-CoV-2-host interactions R-HSA-9705683
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
ESR-mediated signaling R-HSA-8939211
Platelet Aggregation (Plug Formation) R-HSA-76009
Rab regulation of trafficking R-HSA-9007101
Signaling by NOTCH4 R-HSA-9013694
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Metabolism of vitamins and cofactors R-HSA-196854
Signaling by PTK6 R-HSA-8848021
Generic Transcription Pathway R-HSA-212436
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
eNOS activation R-HSA-203615
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by WNT R-HSA-195721
Intracellular signaling by second messengers R-HSA-9006925
PTEN Regulation R-HSA-6807070
Signaling by Nuclear Receptors R-HSA-9006931
CD28 co-stimulation R-HSA-389356
SARS-CoV-2 Infection R-HSA-9694516
Adaptive Immune System R-HSA-1280218
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
AKT phosphorylates targets in the nucleus R-HSA-198693
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Programmed Cell Death R-HSA-5357801
Activation of BH3-only proteins R-HSA-114452
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cellular response to chemical stress R-HSA-9711123
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH R-HSA-157118
Signaling by VEGF R-HSA-194138
AKT-mediated inactivation of FOXO1A R-HSA-211163
GPCR downstream signalling R-HSA-388396
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Degradation R-HSA-6804757
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
CTLA4 inhibitory signaling R-HSA-389513
Regulation of PTEN stability and activity R-HSA-8948751
Activation of BAD and translocation to mitochondria R-HSA-111447
Platelet activation, signaling and aggregation R-HSA-76002
Cell Cycle R-HSA-1640170
G-protein beta:gamma signalling R-HSA-397795
Signaling by ERBB2 R-HSA-1227986
Disease R-HSA-1643685
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Signal Transduction R-HSA-162582
VEGFR2 mediated vascular permeability R-HSA-5218920
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by GPCR R-HSA-372790
Costimulation by the CD28 family R-HSA-388841
Regulation of beta-cell development R-HSA-186712
Regulation of gene expression in beta cells R-HSA-210745
Regulation of localization of FOXO transcription factors R-HSA-9614399
G1/S Transition R-HSA-69206
Infectious disease R-HSA-5663205
Negative regulation of NOTCH4 signaling R-HSA-9604323
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Metabolism of RNA R-HSA-8953854
Cellular responses to stimuli R-HSA-8953897
Apoptosis R-HSA-109581
AKT phosphorylates targets in the cytosol R-HSA-198323
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
S Phase R-HSA-69242
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Cellular responses to stress R-HSA-2262752
Integrin signaling R-HSA-354192
Extra-nuclear estrogen signaling R-HSA-9009391
Downregulation of ERBB2 signaling R-HSA-8863795
Metabolism of cofactors R-HSA-8978934
FOXO-mediated transcription R-HSA-9614085
Negative regulation of the PI3K/AKT network R-HSA-199418
Hemostasis R-HSA-109582
Cell Cycle, Mitotic R-HSA-69278
Gene expression (Transcription) R-HSA-74160
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Membrane Trafficking R-HSA-199991
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
CD28 dependent PI3K/Akt signaling R-HSA-389357
MTOR signalling R-HSA-165159
FLT3 Signaling R-HSA-9607240
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by PTK6 R-HSA-8848021
Cellular response to chemical stress R-HSA-9711123
Signaling by VEGF R-HSA-194138
Cell Cycle, Mitotic R-HSA-69278
Regulation of localization of FOXO transcription factors R-HSA-9614399
Signaling by Interleukins R-HSA-449147
Negative regulation of NOTCH4 signaling R-HSA-9604323
MTOR signalling R-HSA-165159
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Adaptive Immune System R-HSA-1280218
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Programmed Cell Death R-HSA-5357801
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of TP53 Activity R-HSA-5633007
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intrinsic Pathway for Apoptosis R-HSA-109606
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
CD28 co-stimulation R-HSA-389356
TP53 Regulates Metabolic Genes R-HSA-5628897
Apoptosis R-HSA-109581
Regulation of gene expression in beta cells R-HSA-210745
AKT-mediated inactivation of FOXO1A R-HSA-211163
Cytokine Signaling in Immune system R-HSA-1280215
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
ESR-mediated signaling R-HSA-8939211
Mitotic G1 phase and G1/S transition R-HSA-453279
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Downregulation of ERBB2 signaling R-HSA-8863795
Signaling by NOTCH R-HSA-157118
VEGFR2 mediated vascular permeability R-HSA-5218920
Signaling by ERBB2 R-HSA-1227986
Activation of BH3-only proteins R-HSA-114452
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
G-protein beta:gamma signalling R-HSA-397795
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by NOTCH4 R-HSA-9013694
Platelet Aggregation (Plug Formation) R-HSA-76009
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism R-HSA-1430728
Transcriptional Regulation by TP53 R-HSA-3700989
AKT phosphorylates targets in the nucleus R-HSA-198693
Integrin signaling R-HSA-354192
Activation of BAD and translocation to mitochondria R-HSA-111447
eNOS activation R-HSA-203615
FLT3 Signaling R-HSA-9607240
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of beta-cell development R-HSA-186712
Signaling by Nuclear Receptors R-HSA-9006931
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
KEAP1-NFE2L2 pathway R-HSA-9755511
G1/S Transition R-HSA-69206
Negative regulation of the PI3K/AKT network R-HSA-199418
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cellular responses to stimuli R-HSA-8953897
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
SARS-CoV Infections R-HSA-9679506
Signaling by GPCR R-HSA-372790
SARS-CoV-2-host interactions R-HSA-9705683
Costimulation by the CD28 family R-HSA-388841
Metabolism of RNA R-HSA-8953854
CD28 dependent PI3K/Akt signaling R-HSA-389357
TCF dependent signaling in response to WNT R-HSA-201681
Immune System R-HSA-168256
VEGFA-VEGFR2 Pathway R-HSA-4420097
Regulation of TP53 Activity through Acetylation R-HSA-6804758
PI3K/AKT Signaling in Cancer R-HSA-2219528
SARS-CoV-2 Infection R-HSA-9694516
Metabolism of cofactors R-HSA-8978934
GPCR downstream signalling R-HSA-388396
AKT phosphorylates targets in the cytosol R-HSA-198323
S Phase R-HSA-69242
Rab regulation of trafficking R-HSA-9007101
Platelet activation, signaling and aggregation R-HSA-76002
FOXO-mediated transcription R-HSA-9614085
Vesicle-mediated transport R-HSA-5653656
Generic Transcription Pathway R-HSA-212436
G beta:gamma signalling through PI3Kgamma R-HSA-392451
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
PIP3 activates AKT signaling R-HSA-1257604
Infectious disease R-HSA-5663205
Metabolism of vitamins and cofactors R-HSA-196854
Hemostasis R-HSA-109582
Membrane Trafficking R-HSA-199991
CTLA4 inhibitory signaling R-HSA-389513
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Developmental Biology R-HSA-1266738
Regulation of TP53 Degradation R-HSA-6804757
Cell Cycle, Mitotic R-HSA-69278
Cyclin E associated events during G1/S transition R-HSA-69202
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disease R-HSA-1643685
Downregulation of ERBB2 signaling R-HSA-8863795
Activation of BAD and translocation to mitochondria R-HSA-111447
Signaling by Interleukins R-HSA-449147
Regulation of localization of FOXO transcription factors R-HSA-9614399
AKT phosphorylates targets in the cytosol R-HSA-198323
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
AKT phosphorylates targets in the nucleus R-HSA-198693
Hemostasis R-HSA-109582
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Platelet activation, signaling and aggregation R-HSA-76002
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Signaling by PTK6 R-HSA-8848021
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
G1/S Transition R-HSA-69206
FLT3 Signaling R-HSA-9607240
Transcriptional Regulation by TP53 R-HSA-3700989
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
CTLA4 inhibitory signaling R-HSA-389513
TCF dependent signaling in response to WNT R-HSA-201681
Platelet Aggregation (Plug Formation) R-HSA-76009
CD28 dependent PI3K/Akt signaling R-HSA-389357
PTEN Regulation R-HSA-6807070
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Activation of BH3-only proteins R-HSA-114452
Membrane Trafficking R-HSA-199991
Signaling by NOTCH R-HSA-157118
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Rab regulation of trafficking R-HSA-9007101
Regulation of PTEN stability and activity R-HSA-8948751
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by GPCR R-HSA-372790
Vesicle-mediated transport R-HSA-5653656
Metabolism of vitamins and cofactors R-HSA-196854
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGFA-VEGFR2 Pathway R-HSA-4420097
Metabolism of cofactors R-HSA-8978934
eNOS activation R-HSA-203615
Cellular response to chemical stress R-HSA-9711123
SARS-CoV Infections R-HSA-9679506
PIP3 activates AKT signaling R-HSA-1257604
Regulation of TP53 Degradation R-HSA-6804757
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulation of TP53 Activity through Acetylation R-HSA-6804758
TP53 Regulates Metabolic Genes R-HSA-5628897
VEGFR2 mediated vascular permeability R-HSA-5218920
Infectious disease R-HSA-5663205
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Cell Cycle R-HSA-1640170
Cellular responses to stress R-HSA-2262752
MTOR signalling R-HSA-165159
Programmed Cell Death R-HSA-5357801
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Regulation of beta-cell development R-HSA-186712
CD28 co-stimulation R-HSA-389356
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Immune System R-HSA-168256
PI3K/AKT Signaling in Cancer R-HSA-2219528
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by NOTCH4 R-HSA-9013694
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Intracellular signaling by second messengers R-HSA-9006925
SARS-CoV-2 Infection R-HSA-9694516
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of TP53 Expression and Degradation R-HSA-6806003
Generic Transcription Pathway R-HSA-212436
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
FOXO-mediated transcription R-HSA-9614085
Integrin signaling R-HSA-354192
Metabolism of RNA R-HSA-8953854
Regulation of TP53 Activity R-HSA-5633007
Signaling by Nuclear Receptors R-HSA-9006931
Extra-nuclear estrogen signaling R-HSA-9009391
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Metabolism R-HSA-1430728
Signaling by ERBB2 R-HSA-1227986
Regulation of gene expression in beta cells R-HSA-210745
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX2 R-HSA-8878166
S Phase R-HSA-69242
G-protein beta:gamma signalling R-HSA-397795
Signal Transduction R-HSA-162582
KEAP1-NFE2L2 pathway R-HSA-9755511
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
Signaling by VEGF R-HSA-194138
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Signaling by WNT R-HSA-195721
AKT-mediated inactivation of FOXO1A R-HSA-211163
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
GPCR downstream signalling R-HSA-388396
Cellular responses to stimuli R-HSA-8953897
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Costimulation by the CD28 family R-HSA-388841
ESR-mediated signaling R-HSA-8939211
TCF dependent signaling in response to WNT R-HSA-201681
ESR-mediated signaling R-HSA-8939211
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Programmed Cell Death R-HSA-5357801
Signaling by Interleukins R-HSA-449147
SARS-CoV-2-host interactions R-HSA-9705683
Intrinsic Pathway for Apoptosis R-HSA-109606
VEGFR2 mediated vascular permeability R-HSA-5218920
Regulation of gene expression in beta cells R-HSA-210745
CD28 co-stimulation R-HSA-389356
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Hemostasis R-HSA-109582
Metabolism R-HSA-1430728
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by NOTCH R-HSA-157118
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
Platelet Aggregation (Plug Formation) R-HSA-76009
G1/S Transition R-HSA-69206
Metabolism of cofactors R-HSA-8978934
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH4 R-HSA-9013694
Immune System R-HSA-168256
PTEN Regulation R-HSA-6807070
VEGFA-VEGFR2 Pathway R-HSA-4420097
Regulation of TP53 Activity R-HSA-5633007
Transcriptional regulation by RUNX2 R-HSA-8878166
Membrane Trafficking R-HSA-199991
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
CTLA4 inhibitory signaling R-HSA-389513
TP53 Regulates Metabolic Genes R-HSA-5628897
Regulation of beta-cell development R-HSA-186712
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
AKT phosphorylates targets in the cytosol R-HSA-198323
eNOS activation R-HSA-203615
Costimulation by the CD28 family R-HSA-388841
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Activation of BAD and translocation to mitochondria R-HSA-111447
SARS-CoV-2 Infection R-HSA-9694516
Apoptosis R-HSA-109581
CD28 dependent PI3K/Akt signaling R-HSA-389357
Metabolism of RNA R-HSA-8953854
Regulation of TP53 Degradation R-HSA-6804757
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Cellular responses to stimuli R-HSA-8953897
Downregulation of ERBB2 signaling R-HSA-8863795
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
Signaling by ERBB2 R-HSA-1227986
Regulation of TP53 Expression and Degradation R-HSA-6806003
Mitotic G1 phase and G1/S transition R-HSA-453279
Disease R-HSA-1643685
Cellular response to chemical stress R-HSA-9711123
Generic Transcription Pathway R-HSA-212436
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
AKT phosphorylates targets in the nucleus R-HSA-198693
MTOR signalling R-HSA-165159
Regulation of localization of FOXO transcription factors R-HSA-9614399
SARS-CoV Infections R-HSA-9679506
S Phase R-HSA-69242
Intracellular signaling by second messengers R-HSA-9006925
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Signal Transduction R-HSA-162582
Extra-nuclear estrogen signaling R-HSA-9009391
FOXO-mediated transcription R-HSA-9614085
Developmental Biology R-HSA-1266738
Cyclin E associated events during G1/S transition R-HSA-69202
RNA Polymerase II Transcription R-HSA-73857
FLT3 Signaling R-HSA-9607240
Infectious disease R-HSA-5663205
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Cell Cycle R-HSA-1640170
Rab regulation of trafficking R-HSA-9007101
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
PI3K/AKT Signaling in Cancer R-HSA-2219528
GPCR downstream signalling R-HSA-388396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional Regulation by TP53 R-HSA-3700989
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cell Cycle, Mitotic R-HSA-69278
Signaling by VEGF R-HSA-194138
Platelet activation, signaling and aggregation R-HSA-76002
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Signaling by PTK6 R-HSA-8848021
Metabolism of vitamins and cofactors R-HSA-196854
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Regulation of PTEN stability and activity R-HSA-8948751
Vesicle-mediated transport R-HSA-5653656
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Signaling by Nuclear Receptors R-HSA-9006931
Negative regulation of NOTCH4 signaling R-HSA-9604323
G-protein beta:gamma signalling R-HSA-397795
AKT-mediated inactivation of FOXO1A R-HSA-211163
Activation of BH3-only proteins R-HSA-114452
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by WNT R-HSA-195721
Adaptive Immune System R-HSA-1280218
Integrin signaling R-HSA-354192
PIP3 activates AKT signaling R-HSA-1257604
KEAP1-NFE2L2 pathway R-HSA-9755511
Cytokine Signaling in Immune system R-HSA-1280215
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
Signaling by NOTCH4 R-HSA-9013694
Vesicle-mediated transport R-HSA-5653656
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
S Phase R-HSA-69242
Transcriptional Regulation by TP53 R-HSA-3700989
ESR-mediated signaling R-HSA-8939211
VEGFR2 mediated vascular permeability R-HSA-5218920
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Platelet activation, signaling and aggregation R-HSA-76002
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Signaling by Nuclear Receptors R-HSA-9006931
Negative regulation of NOTCH4 signaling R-HSA-9604323
eNOS activation R-HSA-203615
Cell Cycle, Mitotic R-HSA-69278
Adaptive Immune System R-HSA-1280218
Membrane Trafficking R-HSA-199991
Hemostasis R-HSA-109582
Negative regulation of the PI3K/AKT network R-HSA-199418
Regulation of PTEN stability and activity R-HSA-8948751
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Integrin signaling R-HSA-354192
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Intracellular signaling by second messengers R-HSA-9006925
Regulation of TP53 Degradation R-HSA-6804757
G1/S Transition R-HSA-69206
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
SARS-CoV-2 Infection R-HSA-9694516
Signaling by PTK6 R-HSA-8848021
Downregulation of ERBB2 signaling R-HSA-8863795
Intrinsic Pathway for Apoptosis R-HSA-109606
Cellular responses to stress R-HSA-2262752
Regulation of beta-cell development R-HSA-186712
MTOR signalling R-HSA-165159
Signaling by ERBB2 R-HSA-1227986
PI3K/AKT Signaling in Cancer R-HSA-2219528
PTEN Regulation R-HSA-6807070
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by GPCR R-HSA-372790
Regulation of gene expression in beta cells R-HSA-210745
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
RNA Polymerase II Transcription R-HSA-73857
Activation of BAD and translocation to mitochondria R-HSA-111447
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of RNA R-HSA-8953854
AKT phosphorylates targets in the cytosol R-HSA-198323
G-protein beta:gamma signalling R-HSA-397795
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Apoptosis R-HSA-109581
Cellular responses to stimuli R-HSA-8953897
TP53 Regulates Metabolic Genes R-HSA-5628897
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
FLT3 Signaling R-HSA-9607240
Extra-nuclear estrogen signaling R-HSA-9009391
GPCR downstream signalling R-HSA-388396
CTLA4 inhibitory signaling R-HSA-389513
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of TP53 Activity R-HSA-5633007
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle R-HSA-1640170
CD28 dependent PI3K/Akt signaling R-HSA-389357
AKT phosphorylates targets in the nucleus R-HSA-198693
CD28 co-stimulation R-HSA-389356
VEGFA-VEGFR2 Pathway R-HSA-4420097
Activation of BH3-only proteins R-HSA-114452
Signaling by VEGF R-HSA-194138
Rab regulation of trafficking R-HSA-9007101
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
SARS-CoV Infections R-HSA-9679506
Platelet Aggregation (Plug Formation) R-HSA-76009
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Cellular response to chemical stress R-HSA-9711123
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by NOTCH R-HSA-157118
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Metabolism R-HSA-1430728
Developmental Biology R-HSA-1266738
Costimulation by the CD28 family R-HSA-388841
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Generic Transcription Pathway R-HSA-212436
Programmed Cell Death R-HSA-5357801
AKT-mediated inactivation of FOXO1A R-HSA-211163
Signaling by Interleukins R-HSA-449147
Signaling by WNT R-HSA-195721
Infectious disease R-HSA-5663205
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulation of localization of FOXO transcription factors R-HSA-9614399
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic G1 phase and G1/S transition R-HSA-453279
FOXO-mediated transcription R-HSA-9614085
Regulation of TP53 Expression and Degradation R-HSA-6806003
Metabolism of cofactors R-HSA-8978934
Metabolism of vitamins and cofactors R-HSA-196854
Immune System R-HSA-168256
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
AKT phosphorylates targets in the cytosol R-HSA-198323
PIP3 activates AKT signaling R-HSA-1257604
VEGFA-VEGFR2 Pathway R-HSA-4420097
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Activation of BH3-only proteins R-HSA-114452
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Programmed Cell Death R-HSA-5357801
Activation of BAD and translocation to mitochondria R-HSA-111447
Signaling by VEGF R-HSA-194138
G-protein beta:gamma signalling R-HSA-397795
Cellular responses to stress R-HSA-2262752
Vesicle-mediated transport R-HSA-5653656
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Regulation of gene expression in beta cells R-HSA-210745
Intracellular signaling by second messengers R-HSA-9006925
Platelet activation, signaling and aggregation R-HSA-76002
Gene expression (Transcription) R-HSA-74160
CD28 dependent PI3K/Akt signaling R-HSA-389357
Metabolism of RNA R-HSA-8953854
Integrin signaling R-HSA-354192
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
CTLA4 inhibitory signaling R-HSA-389513
Signaling by Nuclear Receptors R-HSA-9006931
eNOS activation R-HSA-203615
Regulation of PTEN stability and activity R-HSA-8948751
Adaptive Immune System R-HSA-1280218
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Apoptosis R-HSA-109581
Infectious disease R-HSA-5663205
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
SARS-CoV-2 Infection R-HSA-9694516
Signaling by GPCR R-HSA-372790
KEAP1-NFE2L2 pathway R-HSA-9755511
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of TP53 Expression and Degradation R-HSA-6806003
SARS-CoV Infections R-HSA-9679506
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Regulation of localization of FOXO transcription factors R-HSA-9614399
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Metabolism R-HSA-1430728
Disease R-HSA-1643685
FLT3 Signaling R-HSA-9607240
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Intrinsic Pathway for Apoptosis R-HSA-109606
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by NOTCH4 R-HSA-9013694
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131
PI3K/AKT Signaling in Cancer R-HSA-2219528
ESR-mediated signaling R-HSA-8939211
TP53 Regulates Metabolic Genes R-HSA-5628897
Rab regulation of trafficking R-HSA-9007101
FOXO-mediated transcription R-HSA-9614085
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Metabolism of cofactors R-HSA-8978934
CD28 co-stimulation R-HSA-389356
Costimulation by the CD28 family R-HSA-388841
Membrane Trafficking R-HSA-199991
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469
AKT-mediated inactivation of FOXO1A R-HSA-211163
Generic Transcription Pathway R-HSA-212436
S Phase R-HSA-69242
Downregulation of ERBB2 signaling R-HSA-8863795
Transcriptional regulation by RUNX2 R-HSA-8878166
Negative regulation of the PI3K/AKT network R-HSA-199418
G1/S Transition R-HSA-69206
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by ERBB2 R-HSA-1227986
Mitotic G1 phase and G1/S transition R-HSA-453279
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Transcriptional Regulation by TP53 R-HSA-3700989
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Metabolism of vitamins and cofactors R-HSA-196854
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Signal Transduction R-HSA-162582
MTOR signalling R-HSA-165159
Regulation of beta-cell development R-HSA-186712
Immune System R-HSA-168256
Platelet Aggregation (Plug Formation) R-HSA-76009
Signaling by PTK6 R-HSA-8848021
VEGFR2 mediated vascular permeability R-HSA-5218920
Cellular response to chemical stress R-HSA-9711123
Extra-nuclear estrogen signaling R-HSA-9009391
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
GPCR downstream signalling R-HSA-388396
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
RNA Polymerase II Transcription R-HSA-73857
Signaling by WNT R-HSA-195721
Developmental Biology R-HSA-1266738
PTEN Regulation R-HSA-6807070
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Interleukins R-HSA-449147
SARS-CoV-2-host interactions R-HSA-9705683
Hemostasis R-HSA-109582
AKT phosphorylates targets in the nucleus R-HSA-198693
Regulation of TP53 Degradation R-HSA-6804757
G beta:gamma signalling through PI3Kgamma R-HSA-392451

Expression Atlas ENSG00000142208
LRG display in Ensembl gene LRG_721
NCBI gene (formerly Entrezgene) 207
GeneCards 391
HGNC Symbol HGNC:391
MIM gene 164730
MIM morbid 615109
UniProtKB Gene Name P31749
WikiGene 207
Gene: FGFR1
Ensembl ID : ENSG00000077782
Description: fibroblast growth factor receptor 1
Gene Synonyms: BFGFR,CD331,CEK,FLG,FLT2,H2,H3,H4,H5,KAL2,N-SAM
26 APIs:
293 Possible Orthologues:

MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by activated point mutants of FGFR1 R-HSA-1839122
MAPK family signaling cascades R-HSA-5683057
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR1 in disease R-HSA-5655302
Downstream signaling of activated FGFR1 R-HSA-5654687
RAF/MAP kinase cascade R-HSA-5673001
Gastrulation R-HSA-9758941
Signal Transduction R-HSA-162582
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
FGFR1 ligand binding and activation R-HSA-190242
Developmental Biology R-HSA-1266738
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K Cascade R-HSA-109704
Signaling by FGFR in disease R-HSA-1226099
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Negative regulation of the PI3K/AKT network R-HSA-199418
IGF1R signaling cascade R-HSA-2428924
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by FGFR1 R-HSA-5654736
L1CAM interactions R-HSA-373760
Signaling by FGFR R-HSA-190236
Formation of paraxial mesoderm R-HSA-9793380
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FRS-mediated FGFR1 signaling R-HSA-5654693
Axon guidance R-HSA-422475
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI-3K cascade:FGFR1 R-HSA-5654689
FGFR1b ligand binding and activation R-HSA-190370
Disease R-HSA-1643685
FGFR1c ligand binding and activation R-HSA-190373
Signal transduction by L1 R-HSA-445144
IRS-mediated signalling R-HSA-112399
Signaling by FGFR1 amplification mutants R-HSA-1839120
Signaling by Insulin receptor R-HSA-74752
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Negative regulation of FGFR1 signaling R-HSA-5654726
PI3K/AKT Signaling in Cancer R-HSA-2219528
FGFR1 mutant receptor activation R-HSA-1839124
Nervous system development R-HSA-9675108
PIP3 activates AKT signaling R-HSA-1257604
SHC-mediated cascade:FGFR1 R-HSA-5654688
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IGF1R signaling cascade R-HSA-2428924
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
PI3K/AKT Signaling in Cancer R-HSA-2219528
FRS-mediated FGFR1 signaling R-HSA-5654693
Signaling by FGFR1 in disease R-HSA-5655302
NCAM signaling for neurite out-growth R-HSA-375165
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR1 R-HSA-5654736
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR R-HSA-190236
L1CAM interactions R-HSA-373760
Signal Transduction R-HSA-162582
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Negative regulation of FGFR1 signaling R-HSA-5654726
FGFR1 mutant receptor activation R-HSA-1839124
Axon guidance R-HSA-422475
MAPK1/MAPK3 signaling R-HSA-5684996
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
IRS-mediated signalling R-HSA-112399
Signaling by FGFR in disease R-HSA-1226099
FGFR1c and Klotho ligand binding and activation R-HSA-190374
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Insulin receptor R-HSA-74752
Signal transduction by L1 R-HSA-445144
PI-3K cascade:FGFR1 R-HSA-5654689
PI3K Cascade R-HSA-109704
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
SHC-mediated cascade:FGFR1 R-HSA-5654688
MAPK family signaling cascades R-HSA-5683057
FGFR1b ligand binding and activation R-HSA-190370
FGFR1 ligand binding and activation R-HSA-190242
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Developmental Biology R-HSA-1266738
Signaling by FGFR1 amplification mutants R-HSA-1839120
Gastrulation R-HSA-9758941
FGFR1c ligand binding and activation R-HSA-190373
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by activated point mutants of FGFR1 R-HSA-1839122
Formation of paraxial mesoderm R-HSA-9793380
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
Signaling by FGFR1 amplification mutants R-HSA-1839120
Formation of paraxial mesoderm R-HSA-9793380
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Insulin receptor R-HSA-74752
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
RAF/MAP kinase cascade R-HSA-5673001
Gastrulation R-HSA-9758941
PI-3K cascade:FGFR1 R-HSA-5654689
Downstream signaling of activated FGFR1 R-HSA-5654687
SHC-mediated cascade:FGFR1 R-HSA-5654688
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by activated point mutants of FGFR1 R-HSA-1839122
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI3K Cascade R-HSA-109704
PIP3 activates AKT signaling R-HSA-1257604
FGFR1c ligand binding and activation R-HSA-190373
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
L1CAM interactions R-HSA-373760
MAPK1/MAPK3 signaling R-HSA-5684996
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by FGFR1 R-HSA-5654736
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Insulin receptor signalling cascade R-HSA-74751
FGFR1 ligand binding and activation R-HSA-190242
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR in disease R-HSA-1226099
IRS-related events triggered by IGF1R R-HSA-2428928
Signal transduction by L1 R-HSA-445144
Axon guidance R-HSA-422475
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Intracellular signaling by second messengers R-HSA-9006925
IRS-mediated signalling R-HSA-112399
Nervous system development R-HSA-9675108
IGF1R signaling cascade R-HSA-2428924
FRS-mediated FGFR1 signaling R-HSA-5654693
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Signaling by FGFR R-HSA-190236
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FGFR1b ligand binding and activation R-HSA-190370
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR R-HSA-190236
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
FRS-mediated FGFR1 signaling R-HSA-5654693
Downstream signaling of activated FGFR1 R-HSA-5654687
IRS-mediated signalling R-HSA-112399
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Signaling by Insulin receptor R-HSA-74752
PI3K Cascade R-HSA-109704
Nervous system development R-HSA-9675108
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Signal transduction by L1 R-HSA-445144
Gastrulation R-HSA-9758941
Signal Transduction R-HSA-162582
FGFR1b ligand binding and activation R-HSA-190370
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of FGFR1 signaling R-HSA-5654726
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
Intracellular signaling by second messengers R-HSA-9006925
Formation of paraxial mesoderm R-HSA-9793380
L1CAM interactions R-HSA-373760
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IGF1R signaling cascade R-HSA-2428924
Signaling by activated point mutants of FGFR1 R-HSA-1839122
IRS-related events triggered by IGF1R R-HSA-2428928
Axon guidance R-HSA-422475
Signaling by FGFR1 amplification mutants R-HSA-1839120
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by FGFR1 R-HSA-5654736
Insulin receptor signalling cascade R-HSA-74751
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Signaling by FGFR in disease R-HSA-1226099
FGFR1c ligand binding and activation R-HSA-190373
NCAM signaling for neurite out-growth R-HSA-375165
MAPK1/MAPK3 signaling R-HSA-5684996
FGFR1 ligand binding and activation R-HSA-190242
Negative regulation of the PI3K/AKT network R-HSA-199418
Developmental Biology R-HSA-1266738
MAPK family signaling cascades R-HSA-5683057
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
SHC-mediated cascade:FGFR1 R-HSA-5654688
FGFR1 mutant receptor activation R-HSA-1839124
Negative regulation of the PI3K/AKT network R-HSA-199418
Nervous system development R-HSA-9675108
FGFR1b ligand binding and activation R-HSA-190370
L1CAM interactions R-HSA-373760
Formation of paraxial mesoderm R-HSA-9793380
Signaling by activated point mutants of FGFR1 R-HSA-1839122
Signaling by FGFR1 R-HSA-5654736
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
IGF1R signaling cascade R-HSA-2428924
Intracellular signaling by second messengers R-HSA-9006925
SHC-mediated cascade:FGFR1 R-HSA-5654688
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FGFR1c ligand binding and activation R-HSA-190373
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signal transduction by L1 R-HSA-445144
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
IRS-mediated signalling R-HSA-112399
Signaling by FGFR1 in disease R-HSA-5655302
Negative regulation of FGFR1 signaling R-HSA-5654726
Signal Transduction R-HSA-162582
Gastrulation R-HSA-9758941
PI3K Cascade R-HSA-109704
Signaling by FGFR1 amplification mutants R-HSA-1839120
Developmental Biology R-HSA-1266738
Signaling by FGFR R-HSA-190236
IRS-related events triggered by IGF1R R-HSA-2428928
FRS-mediated FGFR1 signaling R-HSA-5654693
Disease R-HSA-1643685
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Insulin receptor R-HSA-74752
FGFR1 ligand binding and activation R-HSA-190242
MAPK family signaling cascades R-HSA-5683057
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Axon guidance R-HSA-422475
PI3K/AKT Signaling in Cancer R-HSA-2219528
Insulin receptor signalling cascade R-HSA-74751
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI-3K cascade:FGFR1 R-HSA-5654689
NCAM signaling for neurite out-growth R-HSA-375165
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Signaling by FGFR in disease R-HSA-1226099
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FGFR1 mutant receptor activation R-HSA-1839124
NCAM signaling for neurite out-growth R-HSA-375165
PIP3 activates AKT signaling R-HSA-1257604
Formation of paraxial mesoderm R-HSA-9793380
MAPK1/MAPK3 signaling R-HSA-5684996
Axon guidance R-HSA-422475
FGFR1c ligand binding and activation R-HSA-190373
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR R-HSA-190236
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Disease R-HSA-1643685
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR in disease R-HSA-1226099
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Insulin receptor signalling cascade R-HSA-74751
FGFR1 ligand binding and activation R-HSA-190242
Signal transduction by L1 R-HSA-445144
PI3K Cascade R-HSA-109704
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
RAF/MAP kinase cascade R-HSA-5673001
FGFR1b ligand binding and activation R-HSA-190370
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR1 amplification mutants R-HSA-1839120
Signaling by activated point mutants of FGFR1 R-HSA-1839122
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Gastrulation R-HSA-9758941
Nervous system development R-HSA-9675108
SHC-mediated cascade:FGFR1 R-HSA-5654688
Developmental Biology R-HSA-1266738
Signaling by FGFR1 R-HSA-5654736
Negative regulation of FGFR1 signaling R-HSA-5654726
FRS-mediated FGFR1 signaling R-HSA-5654693
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
L1CAM interactions R-HSA-373760
Downstream signaling of activated FGFR1 R-HSA-5654687
IRS-related events triggered by IGF1R R-HSA-2428928
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR1 in disease R-HSA-5655302
IRS-mediated signalling R-HSA-112399
PI-3K cascade:FGFR1 R-HSA-5654689
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
FGFR1 mutant receptor activation R-HSA-1839124
Formation of paraxial mesoderm R-HSA-9793380
Signaling by FGFR1 R-HSA-5654736
MAPK family signaling cascades R-HSA-5683057
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by FGFR1 in disease R-HSA-5655302
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IGF1R signaling cascade R-HSA-2428924
Disease R-HSA-1643685
Signaling by FGFR in disease R-HSA-1226099
Insulin receptor signalling cascade R-HSA-74751
FGFR1c and Klotho ligand binding and activation R-HSA-190374
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Insulin receptor R-HSA-74752
Signaling by activated point mutants of FGFR1 R-HSA-1839122
PIP3 activates AKT signaling R-HSA-1257604
FRS-mediated FGFR1 signaling R-HSA-5654693
Intracellular signaling by second messengers R-HSA-9006925
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
SHC-mediated cascade:FGFR1 R-HSA-5654688
Axon guidance R-HSA-422475
IRS-mediated signalling R-HSA-112399
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
FGFR1c ligand binding and activation R-HSA-190373
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
L1CAM interactions R-HSA-373760
Signal transduction by L1 R-HSA-445144
PI3K Cascade R-HSA-109704
PI3K/AKT Signaling in Cancer R-HSA-2219528
Downstream signaling of activated FGFR1 R-HSA-5654687
PI-3K cascade:FGFR1 R-HSA-5654689
FGFR1 ligand binding and activation R-HSA-190242
Signaling by FGFR1 amplification mutants R-HSA-1839120
Negative regulation of FGFR1 signaling R-HSA-5654726
Developmental Biology R-HSA-1266738
FGFR1b ligand binding and activation R-HSA-190370
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by FGFR R-HSA-190236
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Negative regulation of the PI3K/AKT network R-HSA-199418
Gastrulation R-HSA-9758941
IRS-related events triggered by IGF1R R-HSA-2428928
FGFR1c ligand binding and activation R-HSA-190373
Disease R-HSA-1643685
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
RAF/MAP kinase cascade R-HSA-5673001
IRS-related events triggered by IGF1R R-HSA-2428928
IRS-mediated signalling R-HSA-112399
SHC-mediated cascade:FGFR1 R-HSA-5654688
Nervous system development R-HSA-9675108
PIP3 activates AKT signaling R-HSA-1257604
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR in disease R-HSA-1226099
Negative regulation of FGFR1 signaling R-HSA-5654726
Developmental Biology R-HSA-1266738
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR1 in disease R-HSA-5655302
PI3K/AKT Signaling in Cancer R-HSA-2219528
FGFR1b ligand binding and activation R-HSA-190370
IGF1R signaling cascade R-HSA-2428924
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FGFR1 ligand binding and activation R-HSA-190242
Insulin receptor signalling cascade R-HSA-74751
Negative regulation of the PI3K/AKT network R-HSA-199418
NCAM signaling for neurite out-growth R-HSA-375165
PI-3K cascade:FGFR1 R-HSA-5654689
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Gastrulation R-HSA-9758941
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by activated point mutants of FGFR1 R-HSA-1839122
Signal transduction by L1 R-HSA-445144
L1CAM interactions R-HSA-373760
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
FRS-mediated FGFR1 signaling R-HSA-5654693
FGFR1 mutant receptor activation R-HSA-1839124
Formation of paraxial mesoderm R-HSA-9793380
Signaling by FGFR R-HSA-190236
FGFR1c and Klotho ligand binding and activation R-HSA-190374
PI3K Cascade R-HSA-109704
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by FGFR1 amplification mutants R-HSA-1839120
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR1 R-HSA-5654736
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signaling of activated FGFR1 R-HSA-5654687
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
FGFR1c ligand binding and activation R-HSA-190373
IGF1R signaling cascade R-HSA-2428924
Nervous system development R-HSA-9675108
FGFR1 ligand binding and activation R-HSA-190242
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR R-HSA-190236
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Insulin receptor signalling cascade R-HSA-74751
L1CAM interactions R-HSA-373760
Intracellular signaling by second messengers R-HSA-9006925
Signaling by activated point mutants of FGFR1 R-HSA-1839122
PIP3 activates AKT signaling R-HSA-1257604
Signaling by FGFR1 in disease R-HSA-5655302
Signal transduction by L1 R-HSA-445144
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
Signaling by FGFR1 R-HSA-5654736
IRS-mediated signalling R-HSA-112399
Signaling by FGFR in disease R-HSA-1226099
NCAM signaling for neurite out-growth R-HSA-375165
IRS-related events triggered by IGF1R R-HSA-2428928
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
Developmental Biology R-HSA-1266738
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by FGFR1 amplification mutants R-HSA-1839120
Axon guidance R-HSA-422475
FGFR1c and Klotho ligand binding and activation R-HSA-190374
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Insulin receptor R-HSA-74752
Formation of paraxial mesoderm R-HSA-9793380
SHC-mediated cascade:FGFR1 R-HSA-5654688
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K Cascade R-HSA-109704
FRS-mediated FGFR1 signaling R-HSA-5654693
MAPK family signaling cascades R-HSA-5683057
Gastrulation R-HSA-9758941
RAF/MAP kinase cascade R-HSA-5673001
FGFR1b ligand binding and activation R-HSA-190370
Developmental Biology R-HSA-1266738
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR R-HSA-190236
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FGFR1 mutant receptor activation R-HSA-1839124
Signal Transduction R-HSA-162582
IRS-related events triggered by IGF1R R-HSA-2428928
Formation of paraxial mesoderm R-HSA-9793380
PI3K Cascade R-HSA-109704
Disease R-HSA-1643685
L1CAM interactions R-HSA-373760
Signal transduction by L1 R-HSA-445144
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by FGFR1 in disease R-HSA-5655302
MAPK family signaling cascades R-HSA-5683057
IRS-mediated signalling R-HSA-112399
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by activated point mutants of FGFR1 R-HSA-1839122
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919
Signaling by FGFR1 R-HSA-5654736
Signaling by FGFR1 amplification mutants R-HSA-1839120
FGFR1c and Klotho ligand binding and activation R-HSA-190374
Signaling by Insulin receptor R-HSA-74752
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF/MAP kinase cascade R-HSA-5673001
SHC-mediated cascade:FGFR1 R-HSA-5654688
Axon guidance R-HSA-422475
IGF1R signaling cascade R-HSA-2428924
MAPK1/MAPK3 signaling R-HSA-5684996
Nervous system development R-HSA-9675108
Downstream signaling of activated FGFR1 R-HSA-5654687
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Gastrulation R-HSA-9758941
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
NCAM signaling for neurite out-growth R-HSA-375165
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219
Insulin receptor signalling cascade R-HSA-74751
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
FGFR1b ligand binding and activation R-HSA-190370
FGFR1 ligand binding and activation R-HSA-190242
FGFR1c ligand binding and activation R-HSA-190373
Signaling by FGFR in disease R-HSA-1226099
FRS-mediated FGFR1 signaling R-HSA-5654693

Expression Atlas ENSG00000077782
LRG display in Ensembl gene LRG_993
NCBI gene (formerly Entrezgene) 2260
GeneCards 3688
HGNC Symbol HGNC:3688
MIM gene 136350
MIM morbid 615465
UniProtKB Gene Name P11362
WikiGene 2260
Gene: PRKACG
Ensembl ID : ENSG00000165059
Description: protein kinase cAMP-activated catalytic subunit gamma
Gene Synonyms: PKACG
1 APIs:
365 Possible Orthologues:

Plasma lipoprotein assembly R-HSA-8963898
Transport of small molecules R-HSA-382551
Integration of energy metabolism R-HSA-163685
G-protein mediated events R-HSA-112040
Disease R-HSA-1643685
Immune System R-HSA-168256
Degradation of GLI1 by the proteasome R-HSA-5610780
Ca-dependent events R-HSA-111996
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Hemostasis R-HSA-109582
Factors involved in megakaryocyte development and platelet production R-HSA-983231
DAG and IP3 signaling R-HSA-1489509
Signal Transduction R-HSA-162582
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720
MAPK6/MAPK4 signaling R-HSA-5687128
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358
ROBO receptors bind AKAP5 R-HSA-9010642
G alpha (i) signalling events R-HSA-418594
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
PLC beta mediated events R-HSA-112043
PKA activation in glucagon signalling R-HSA-164378
Signaling by ROBO receptors R-HSA-376176
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
VEGFA-VEGFR2 Pathway R-HSA-4420097
C-type lectin receptors (CLRs) R-HSA-5621481
Triglyceride catabolism R-HSA-163560
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676
Opioid Signalling R-HSA-111885
Developmental Biology R-HSA-1266738
Post NMDA receptor activation events R-HSA-438064
CD209 (DC-SIGN) signaling R-HSA-5621575
Glycolysis R-HSA-70171
RET signaling R-HSA-8853659
GPCR downstream signalling R-HSA-388396
Neuronal System R-HSA-112316
Signaling by Hedgehog R-HSA-5358351
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040
Leishmania infection R-HSA-9658195
Glucose metabolism R-HSA-70326
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Metabolism R-HSA-1430728
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
Leishmania parasite growth and survival R-HSA-9664433
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600
Hedgehog 'off' state R-HSA-5610787
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
MAPK family signaling cascades R-HSA-5683057
Calmodulin induced events R-HSA-111933
Aquaporin-mediated transport R-HSA-445717
Intracellular signaling by second messengers R-HSA-9006925
Triglyceride metabolism R-HSA-8979227
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Rap1 signalling R-HSA-392517
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by VEGF R-HSA-194138
PKA activation R-HSA-163615
Signaling by GPCR R-HSA-372790
Metabolism of carbohydrates R-HSA-71387
Glucagon signaling in metabolic regulation R-HSA-163359
GPER1 signaling R-HSA-9634597
G alpha (s) signalling events R-HSA-418555
PKA-mediated phosphorylation of CREB R-HSA-111931
Regulation of insulin secretion R-HSA-422356
DARPP-32 events R-HSA-180024
Nervous system development R-HSA-9675108
Adaptive Immune System R-HSA-1280218
HDL assembly R-HSA-8963896
CaM pathway R-HSA-111997
Metabolism of lipids R-HSA-556833
Transmission across Chemical Synapses R-HSA-112315
DARPP-32 events R-HSA-180024
PKA activation in glucagon signalling R-HSA-164378
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
RET signaling R-HSA-8853659
Immune System R-HSA-168256
G alpha (s) signalling events R-HSA-418555
Leishmania parasite growth and survival R-HSA-9664433
Opioid Signalling R-HSA-111885
GPCR downstream signalling R-HSA-388396
Innate Immune System R-HSA-168249
Glycolysis R-HSA-70171
HDL assembly R-HSA-8963896
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676
Disease R-HSA-1643685
Glucose metabolism R-HSA-70326
PKA-mediated phosphorylation of CREB R-HSA-111931
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Glucagon signaling in metabolic regulation R-HSA-163359
PLC beta mediated events R-HSA-112043
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040
Developmental Biology R-HSA-1266738
Neuronal System R-HSA-112316
Ca-dependent events R-HSA-111996
Signaling by ROBO receptors R-HSA-376176
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog 'off' state R-HSA-5610787
Metabolism R-HSA-1430728
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Aquaporin-mediated transport R-HSA-445717
Signaling by GPCR R-HSA-372790
G-protein mediated events R-HSA-112040
Triglyceride catabolism R-HSA-163560
Integration of energy metabolism R-HSA-163685
Transport of small molecules R-HSA-382551
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of carbohydrates R-HSA-71387
Metabolism of lipids R-HSA-556833
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by VEGF R-HSA-194138
Regulation of insulin secretion R-HSA-422356
Hemostasis R-HSA-109582
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Post NMDA receptor activation events R-HSA-438064
Axon guidance R-HSA-422475
DAG and IP3 signaling R-HSA-1489509
VEGFA-VEGFR2 Pathway R-HSA-4420097
Triglyceride metabolism R-HSA-8979227
CaM pathway R-HSA-111997
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358
ROBO receptors bind AKAP5 R-HSA-9010642
Transmission across Chemical Synapses R-HSA-112315
G alpha (i) signalling events R-HSA-418594
PKA activation R-HSA-163615
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720
Rap1 signalling R-HSA-392517
CD209 (DC-SIGN) signaling R-HSA-5621575
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Degradation of GLI2 by the proteasome R-HSA-5610783
Infectious disease R-HSA-5663205
GPER1 signaling R-HSA-9634597
Leishmania infection R-HSA-9658195
MAPK family signaling cascades R-HSA-5683057
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600
C-type lectin receptors (CLRs) R-HSA-5621481
Calmodulin induced events R-HSA-111933
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Plasma lipoprotein assembly R-HSA-8963898
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Signaling by Hedgehog R-HSA-5358351
Nervous system development R-HSA-9675108

Expression Atlas ENSG00000165059
LRG display in Ensembl gene LRG_1004
NCBI gene (formerly Entrezgene) 5568
GeneCards 9382
HGNC Symbol HGNC:9382
MIM gene 176893
MIM morbid 616176
UniProtKB Gene Name P22612
WikiGene 5568
Gene: ACVR2B
Ensembl ID : ENSG00000114739
Description: activin A receptor type 2B
Gene Synonyms: ACTR-IIB
1 APIs:
259 Possible Orthologues:

Signaling by Activin R-HSA-1502540
Signaling by TGFB family members R-HSA-9006936
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Signaling by NODAL R-HSA-1181150
Regulation of signaling by NODAL R-HSA-1433617
Signaling by BMP R-HSA-201451
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
Signaling by Activin R-HSA-1502540
Developmental Biology R-HSA-1266738
Regulation of signaling by NODAL R-HSA-1433617
Signaling by BMP R-HSA-201451
Signaling by NODAL R-HSA-1181150
Signaling by Activin R-HSA-1502540
Regulation of signaling by NODAL R-HSA-1433617
Signaling by NODAL R-HSA-1181150
Signaling by BMP R-HSA-201451
Developmental Biology R-HSA-1266738
Signaling by TGFB family members R-HSA-9006936
Signal Transduction R-HSA-162582
Signaling by Activin R-HSA-1502540
Signal Transduction R-HSA-162582
Signaling by NODAL R-HSA-1181150
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Developmental Biology R-HSA-1266738
Regulation of signaling by NODAL R-HSA-1433617
Signaling by TGFB family members R-HSA-9006936
Signaling by Activin R-HSA-1502540
Signaling by NODAL R-HSA-1181150
Signal Transduction R-HSA-162582
Signaling by BMP R-HSA-201451
Developmental Biology R-HSA-1266738
Regulation of signaling by NODAL R-HSA-1433617
Regulation of signaling by NODAL R-HSA-1433617
Signaling by TGFB family members R-HSA-9006936
Signaling by NODAL R-HSA-1181150
Signaling by Activin R-HSA-1502540
Signal Transduction R-HSA-162582
Signaling by BMP R-HSA-201451
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Signaling by BMP R-HSA-201451
Developmental Biology R-HSA-1266738
Regulation of signaling by NODAL R-HSA-1433617
Signaling by TGFB family members R-HSA-9006936
Signaling by NODAL R-HSA-1181150
Signaling by Activin R-HSA-1502540
Signaling by BMP R-HSA-201451
Developmental Biology R-HSA-1266738
Regulation of signaling by NODAL R-HSA-1433617
Signaling by TGFB family members R-HSA-9006936
Signal Transduction R-HSA-162582
Signaling by Activin R-HSA-1502540
Signaling by NODAL R-HSA-1181150
Signaling by Activin R-HSA-1502540
Signaling by NODAL R-HSA-1181150
Signaling by TGFB family members R-HSA-9006936
Regulation of signaling by NODAL R-HSA-1433617
Signaling by BMP R-HSA-201451
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Signaling by BMP R-HSA-201451
Signaling by NODAL R-HSA-1181150
Developmental Biology R-HSA-1266738
Signaling by TGFB family members R-HSA-9006936
Regulation of signaling by NODAL R-HSA-1433617
Signaling by Activin R-HSA-1502540
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000114739
NCBI gene (formerly Entrezgene) 93
GeneCards 174
HGNC Symbol HGNC:174
MIM gene 602730
MIM morbid 613751
UniProtKB Gene Name Q13705
WikiGene 93
Gene: MAP3K1
Ensembl ID : ENSG00000095015
Description: mitogen-activated protein kinase kinase kinase 1
Gene Synonyms: MAPKKK1,MEKK,MEKK1
1 APIs:
160 Possible Orthologues:

Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
FCERI mediated MAPK activation R-HSA-2871796
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll-like Receptor Cascades R-HSA-168898
Immune System R-HSA-168256
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Immune System R-HSA-168256
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
TRAF6 mediated NF-kB activation R-HSA-933542
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
FCERI mediated MAPK activation R-HSA-2871796
Innate Immune System R-HSA-168249
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Innate Immune System R-HSA-168249
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll-like Receptor Cascades R-HSA-168898
Immune System R-HSA-168256
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated NF-kB activation R-HSA-933542
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
FCERI mediated MAPK activation R-HSA-2871796
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88 cascade initiated on plasma membrane R-HSA-975871
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll-like Receptor Cascades R-HSA-168898
Immune System R-HSA-168256
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88 dependent cascade initiated on endosome R-HSA-975155
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Innate Immune System R-HSA-168249
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Immune System R-HSA-168256
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88 cascade initiated on plasma membrane R-HSA-975871
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MyD88 dependent cascade initiated on endosome R-HSA-975155
Innate Immune System R-HSA-168249
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRAF6 mediated NF-kB activation R-HSA-933542
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Immune System R-HSA-168256
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
FCERI mediated MAPK activation R-HSA-2871796
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll-like Receptor Cascades R-HSA-168898
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Innate Immune System R-HSA-168249
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated NF-kB activation R-HSA-933542
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRAF6 mediated NF-kB activation R-HSA-933542
Innate Immune System R-HSA-168249
FCERI mediated MAPK activation R-HSA-2871796
MyD88 cascade initiated on plasma membrane R-HSA-975871
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Immune System R-HSA-168256
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Immune System R-HSA-168256
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Innate Immune System R-HSA-168249
Toll-like Receptor Cascades R-HSA-168898
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRAF6 mediated NF-kB activation R-HSA-933542
Immune System R-HSA-168256
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
FCERI mediated MAPK activation R-HSA-2871796
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Innate Immune System R-HSA-168249
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll-like Receptor Cascades R-HSA-168898
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88 dependent cascade initiated on endosome R-HSA-975155
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Innate Immune System R-HSA-168249
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
FCERI mediated MAPK activation R-HSA-2871796
Immune System R-HSA-168256
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138

Expression Atlas ENSG00000095015
NCBI gene (formerly Entrezgene) 4214
GeneCards 6848
HGNC Symbol HGNC:6848
MIM gene 600982
MIM morbid 613762
UniProtKB Gene Name Q13233
WikiGene 4214
Gene: TGFBR1
Ensembl ID : ENSG00000106799
Description: transforming growth factor beta receptor 1
Gene Synonyms: ACVRLK4,ALK-5,ALK5,ESS1,MSSE,TBR-I,TBRI
2 APIs:
236 Possible Orthologues:

Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Downregulation of TGF-beta receptor signaling R-HSA-2173788
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by TGF-beta Receptor Complex R-HSA-170834
Loss of Function of TGFBR2 in Cancer R-HSA-3642278
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signaling by TGFB family members R-HSA-9006936
Post-translational protein modification R-HSA-597592
TGFBR1 KD Mutants in Cancer R-HSA-3656532
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356
UCH proteinases R-HSA-5689603
Signal Transduction R-HSA-162582
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
Disease R-HSA-1643685
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by TGFB family members R-HSA-9006936
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356
Ub-specific processing proteases R-HSA-5689880
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Signaling by TGF-beta Receptor Complex R-HSA-170834
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Disease R-HSA-1643685
TGFBR1 KD Mutants in Cancer R-HSA-3656532
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Deubiquitination R-HSA-5688426
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
Loss of Function of TGFBR2 in Cancer R-HSA-3642278
Downregulation of TGF-beta receptor signaling R-HSA-2173788
Post-translational protein modification R-HSA-597592
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356
Disease R-HSA-1643685
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signal Transduction R-HSA-162582
Ub-specific processing proteases R-HSA-5689880
Deubiquitination R-HSA-5688426
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790
Downregulation of TGF-beta receptor signaling R-HSA-2173788
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of proteins R-HSA-392499
TGFBR1 KD Mutants in Cancer R-HSA-3656532
TGF-beta receptor signaling activates SMADs R-HSA-2173789
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Loss of Function of TGFBR2 in Cancer R-HSA-3642278
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Signaling by TGFB family members R-HSA-9006936
Signaling by TGF-beta Receptor Complex R-HSA-170834
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Disease R-HSA-1643685
Signaling by TGFB family members R-HSA-9006936
Loss of Function of TGFBR2 in Cancer R-HSA-3642278
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Signal Transduction R-HSA-162582
TGFBR1 KD Mutants in Cancer R-HSA-3656532
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Downregulation of TGF-beta receptor signaling R-HSA-2173788
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Signaling by TGF-beta Receptor Complex R-HSA-170834
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349
Post-translational protein modification R-HSA-597592
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790
Downregulation of TGF-beta receptor signaling R-HSA-2173788
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Deubiquitination R-HSA-5688426
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790
UCH proteinases R-HSA-5689603
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349
Ub-specific processing proteases R-HSA-5689880
Signaling by TGFB family members R-HSA-9006936
Post-translational protein modification R-HSA-597592
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TGF-beta receptor signaling activates SMADs R-HSA-2173789
TGFBR1 KD Mutants in Cancer R-HSA-3656532
Loss of Function of TGFBR2 in Cancer R-HSA-3642278
Metabolism of proteins R-HSA-392499
Signaling by TGF-beta Receptor Complex R-HSA-170834
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Signal Transduction R-HSA-162582
Deubiquitination R-HSA-5688426
Loss of Function of TGFBR2 in Cancer R-HSA-3642278
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Ub-specific processing proteases R-HSA-5689880
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by TGFB family members R-HSA-9006936
Signaling by TGF-beta Receptor Complex R-HSA-170834
Downregulation of TGF-beta receptor signaling R-HSA-2173788
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Metabolism of proteins R-HSA-392499
TGFBR1 KD Mutants in Cancer R-HSA-3656532
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356
Disease R-HSA-1643685
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Loss of Function of TGFBR2 in Cancer R-HSA-3642278
Downregulation of TGF-beta receptor signaling R-HSA-2173788
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of proteins R-HSA-392499
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790
Signaling by TGF-beta Receptor Complex R-HSA-170834
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Ub-specific processing proteases R-HSA-5689880
Signaling by TGFB family members R-HSA-9006936
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Post-translational protein modification R-HSA-597592
TGFBR1 KD Mutants in Cancer R-HSA-3656532
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Disease R-HSA-1643685
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349
Deubiquitination R-HSA-5688426
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
UCH proteinases R-HSA-5689603
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790
Signal Transduction R-HSA-162582
Ub-specific processing proteases R-HSA-5689880
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Metabolism of proteins R-HSA-392499
Signaling by TGF-beta Receptor Complex R-HSA-170834
TGFBR1 KD Mutants in Cancer R-HSA-3656532
Post-translational protein modification R-HSA-597592
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356
Downregulation of TGF-beta receptor signaling R-HSA-2173788
Loss of Function of TGFBR2 in Cancer R-HSA-3642278
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Deubiquitination R-HSA-5688426
Signaling by TGF-beta Receptor Complex R-HSA-170834
TGFBR1 KD Mutants in Cancer R-HSA-3656532
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Loss of Function of TGFBR2 in Cancer R-HSA-3642278
Downregulation of TGF-beta receptor signaling R-HSA-2173788
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
UCH proteinases R-HSA-5689603
Signaling by TGFB family members R-HSA-9006936
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Ub-specific processing proteases R-HSA-5689880
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349
Post-translational protein modification R-HSA-597592
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790
Signal Transduction R-HSA-162582
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Loss of Function of TGFBR2 in Cancer R-HSA-3642278
Metabolism of proteins R-HSA-392499
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Signaling by TGFB family members R-HSA-9006936
Disease R-HSA-1643685
TGFBR1 KD Mutants in Cancer R-HSA-3656532
Deubiquitination R-HSA-5688426
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Post-translational protein modification R-HSA-597592
Signal Transduction R-HSA-162582
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
UCH proteinases R-HSA-5689603
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Ub-specific processing proteases R-HSA-5689880
Downregulation of TGF-beta receptor signaling R-HSA-2173788
Signaling by TGF-beta Receptor Complex R-HSA-170834
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790

Expression Atlas ENSG00000106799
NCBI gene (formerly Entrezgene) 7046
GeneCards 11772
HGNC Symbol HGNC:11772
MIM gene 190181
MIM morbid 609192
UniProtKB Gene Name Q5T7S2
WikiGene 7046