Ensembl ID : ENSG00000089022
Description: MAPK activated protein kinase 5
Gene Synonyms: MK5,PRAK
1 APIs:
179 Possible Orthologues:

Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Oxidative Stress Induced Senescence R-HSA-2559580
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
MAPK family signaling cascades R-HSA-5683057
Cellular Senescence R-HSA-2559583
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity R-HSA-5633007
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK6/MAPK4 signaling R-HSA-5687128
MAPK6/MAPK4 signaling R-HSA-5687128
Oxidative Stress Induced Senescence R-HSA-2559580
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity R-HSA-5633007
Regulation of TP53 Activity R-HSA-5633007
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stress R-HSA-2262752
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Cellular Senescence R-HSA-2559583
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity R-HSA-5633007
Oxidative Stress Induced Senescence R-HSA-2559580
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
MAPK family signaling cascades R-HSA-5683057
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Cellular Senescence R-HSA-2559583
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of TP53 Activity R-HSA-5633007
MAPK family signaling cascades R-HSA-5683057
Transcriptional Regulation by TP53 R-HSA-3700989
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
MAPK6/MAPK4 signaling R-HSA-5687128
Oxidative Stress Induced Senescence R-HSA-2559580
Transcriptional Regulation by TP53 R-HSA-3700989
MAPK family signaling cascades R-HSA-5683057
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
Oxidative Stress Induced Senescence R-HSA-2559580
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of TP53 Activity R-HSA-5633007
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Oxidative Stress Induced Senescence R-HSA-2559580
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stimuli R-HSA-8953897
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Regulation of TP53 Activity R-HSA-5633007
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583

Expression Atlas ENSG00000089022
NCBI gene (formerly Entrezgene) 8550
GeneCards 6889
HGNC Symbol HGNC:6889
MIM gene 606723
MIM morbid 619869
UniProtKB Gene Name R4GN93
WikiGene 8550
Gene: GSK3A
Ensembl ID : ENSG00000105723
Description: glycogen synthase kinase 3 alpha
Gene Synonyms:
4 APIs:
259 Possible Orthologues:

Late SARS-CoV-2 Infection Events R-HSA-9772573
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signal Transduction R-HSA-162582
IRE1alpha activates chaperones R-HSA-381070
AKT phosphorylates targets in the cytosol R-HSA-198323
Translation of Structural Proteins R-HSA-9683701
Infection with Mycobacterium tuberculosis R-HSA-9635486
Disease R-HSA-1643685
XBP1(S) activates chaperone genes R-HSA-381038
Cellular responses to stimuli R-HSA-8953897
SARS-CoV-1 Infection R-HSA-9678108
Maturation of nucleoprotein R-HSA-9683610
PIP3 activates AKT signaling R-HSA-1257604
Unfolded Protein Response (UPR) R-HSA-381119
Intracellular signaling by second messengers R-HSA-9006925
SARS-CoV Infections R-HSA-9679506
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Maturation of nucleoprotein R-HSA-9694631
SARS-CoV-2 Infection R-HSA-9694516
Cellular responses to stress R-HSA-2262752
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Response of Mtb to phagocytosis R-HSA-9637690
Translation of Structural Proteins R-HSA-9694635
Suppression of apoptosis R-HSA-9635465
Infectious disease R-HSA-5663205
PI3K/AKT Signaling in Cancer R-HSA-2219528
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Translation of Structural Proteins R-HSA-9683701
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
PI3K/AKT Signaling in Cancer R-HSA-2219528
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-2 Infection R-HSA-9694516
Cellular responses to stimuli R-HSA-8953897
Infection with Mycobacterium tuberculosis R-HSA-9635486
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Translation of Structural Proteins R-HSA-9694635
Suppression of apoptosis R-HSA-9635465
IRE1alpha activates chaperones R-HSA-381070
Maturation of nucleoprotein R-HSA-9694631
PIP3 activates AKT signaling R-HSA-1257604
SARS-CoV Infections R-HSA-9679506
Late SARS-CoV-2 Infection Events R-HSA-9772573
XBP1(S) activates chaperone genes R-HSA-381038
Response of Mtb to phagocytosis R-HSA-9637690
Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Maturation of nucleoprotein R-HSA-9683610
AKT phosphorylates targets in the cytosol R-HSA-198323
Intracellular signaling by second messengers R-HSA-9006925
Unfolded Protein Response (UPR) R-HSA-381119
Intracellular signaling by second messengers R-HSA-9006925
PI3K/AKT Signaling in Cancer R-HSA-2219528
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
SARS-CoV Infections R-HSA-9679506
Signal Transduction R-HSA-162582
AKT phosphorylates targets in the cytosol R-HSA-198323
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Unfolded Protein Response (UPR) R-HSA-381119
Response of Mtb to phagocytosis R-HSA-9637690
Infectious disease R-HSA-5663205
Maturation of nucleoprotein R-HSA-9694631
SARS-CoV-2 Infection R-HSA-9694516
XBP1(S) activates chaperone genes R-HSA-381038
Cellular responses to stimuli R-HSA-8953897
Late SARS-CoV-2 Infection Events R-HSA-9772573
SARS-CoV-1 Infection R-HSA-9678108
Maturation of nucleoprotein R-HSA-9683610
PIP3 activates AKT signaling R-HSA-1257604
Translation of Structural Proteins R-HSA-9683701
Cellular responses to stress R-HSA-2262752
Disease R-HSA-1643685
IRE1alpha activates chaperones R-HSA-381070
Infection with Mycobacterium tuberculosis R-HSA-9635486
Translation of Structural Proteins R-HSA-9694635
Suppression of apoptosis R-HSA-9635465
SARS-CoV-2 Infection R-HSA-9694516
AKT phosphorylates targets in the cytosol R-HSA-198323
XBP1(S) activates chaperone genes R-HSA-381038
Response of Mtb to phagocytosis R-HSA-9637690
Signal Transduction R-HSA-162582
Infection with Mycobacterium tuberculosis R-HSA-9635486
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
IRE1alpha activates chaperones R-HSA-381070
Translation of Structural Proteins R-HSA-9694635
Suppression of apoptosis R-HSA-9635465
Maturation of nucleoprotein R-HSA-9683610
PI3K/AKT Signaling in Cancer R-HSA-2219528
SARS-CoV-1 Infection R-HSA-9678108
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Unfolded Protein Response (UPR) R-HSA-381119
Intracellular signaling by second messengers R-HSA-9006925
Cellular responses to stimuli R-HSA-8953897
SARS-CoV Infections R-HSA-9679506
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Infectious disease R-HSA-5663205
Maturation of nucleoprotein R-HSA-9694631
Late SARS-CoV-2 Infection Events R-HSA-9772573
Translation of Structural Proteins R-HSA-9683701
Translation of Structural Proteins R-HSA-9683701
SARS-CoV-2 Infection R-HSA-9694516
XBP1(S) activates chaperone genes R-HSA-381038
AKT phosphorylates targets in the cytosol R-HSA-198323
Signal Transduction R-HSA-162582
Late SARS-CoV-2 Infection Events R-HSA-9772573
Cellular responses to stress R-HSA-2262752
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Response of Mtb to phagocytosis R-HSA-9637690
Suppression of apoptosis R-HSA-9635465
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Translation of Structural Proteins R-HSA-9694635
Maturation of nucleoprotein R-HSA-9683610
Infectious disease R-HSA-5663205
Maturation of nucleoprotein R-HSA-9694631
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Unfolded Protein Response (UPR) R-HSA-381119
SARS-CoV Infections R-HSA-9679506
Cellular responses to stimuli R-HSA-8953897
SARS-CoV-1 Infection R-HSA-9678108
PI3K/AKT Signaling in Cancer R-HSA-2219528
IRE1alpha activates chaperones R-HSA-381070
Disease R-HSA-1643685
Infection with Mycobacterium tuberculosis R-HSA-9635486
Response of Mtb to phagocytosis R-HSA-9637690
Disease R-HSA-1643685
Infection with Mycobacterium tuberculosis R-HSA-9635486
SARS-CoV-2 Infection R-HSA-9694516
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
XBP1(S) activates chaperone genes R-HSA-381038
Translation of Structural Proteins R-HSA-9683701
Unfolded Protein Response (UPR) R-HSA-381119
Infectious disease R-HSA-5663205
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
AKT phosphorylates targets in the cytosol R-HSA-198323
SARS-CoV Infections R-HSA-9679506
Cellular responses to stress R-HSA-2262752
Maturation of nucleoprotein R-HSA-9683610
Translation of Structural Proteins R-HSA-9694635
SARS-CoV-1 Infection R-HSA-9678108
PI3K/AKT Signaling in Cancer R-HSA-2219528
Maturation of nucleoprotein R-HSA-9694631
IRE1alpha activates chaperones R-HSA-381070
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Suppression of apoptosis R-HSA-9635465
Late SARS-CoV-2 Infection Events R-HSA-9772573
PIP3 activates AKT signaling R-HSA-1257604
SARS-CoV-2 Infection R-HSA-9694516
Translation of Structural Proteins R-HSA-9683701
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
SARS-CoV-1 Infection R-HSA-9678108
Translation of Structural Proteins R-HSA-9694635
Intracellular signaling by second messengers R-HSA-9006925
Infectious disease R-HSA-5663205
Suppression of apoptosis R-HSA-9635465
Maturation of nucleoprotein R-HSA-9694631
XBP1(S) activates chaperone genes R-HSA-381038
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular responses to stress R-HSA-2262752
Unfolded Protein Response (UPR) R-HSA-381119
Disease R-HSA-1643685
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
IRE1alpha activates chaperones R-HSA-381070
SARS-CoV Infections R-HSA-9679506
Maturation of nucleoprotein R-HSA-9683610
AKT phosphorylates targets in the cytosol R-HSA-198323
Late SARS-CoV-2 Infection Events R-HSA-9772573
Response of Mtb to phagocytosis R-HSA-9637690
Infection with Mycobacterium tuberculosis R-HSA-9635486
Cellular responses to stimuli R-HSA-8953897
Unfolded Protein Response (UPR) R-HSA-381119
Infectious disease R-HSA-5663205
Intracellular signaling by second messengers R-HSA-9006925
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
AKT phosphorylates targets in the cytosol R-HSA-198323
Signal Transduction R-HSA-162582
Infection with Mycobacterium tuberculosis R-HSA-9635486
Response of Mtb to phagocytosis R-HSA-9637690
SARS-CoV-1 Infection R-HSA-9678108
PI3K/AKT Signaling in Cancer R-HSA-2219528
Late SARS-CoV-2 Infection Events R-HSA-9772573
Translation of Structural Proteins R-HSA-9694635
Disease R-HSA-1643685
SARS-CoV-2 Infection R-HSA-9694516
Maturation of nucleoprotein R-HSA-9694631
PIP3 activates AKT signaling R-HSA-1257604
Cellular responses to stress R-HSA-2262752
SARS-CoV Infections R-HSA-9679506
Suppression of apoptosis R-HSA-9635465
XBP1(S) activates chaperone genes R-HSA-381038
Translation of Structural Proteins R-HSA-9683701
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
IRE1alpha activates chaperones R-HSA-381070
Maturation of nucleoprotein R-HSA-9683610
PI3K/AKT Signaling in Cancer R-HSA-2219528
Unfolded Protein Response (UPR) R-HSA-381119
Maturation of nucleoprotein R-HSA-9694631
SARS-CoV-2 Infection R-HSA-9694516
Cellular responses to stress R-HSA-2262752
AKT phosphorylates targets in the cytosol R-HSA-198323
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SARS-CoV Infections R-HSA-9679506
Translation of Structural Proteins R-HSA-9694635
XBP1(S) activates chaperone genes R-HSA-381038
Response of Mtb to phagocytosis R-HSA-9637690
Maturation of nucleoprotein R-HSA-9683610
IRE1alpha activates chaperones R-HSA-381070
PIP3 activates AKT signaling R-HSA-1257604
Late SARS-CoV-2 Infection Events R-HSA-9772573
Translation of Structural Proteins R-HSA-9683701
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Infection with Mycobacterium tuberculosis R-HSA-9635486
Disease R-HSA-1643685
SARS-CoV-1 Infection R-HSA-9678108
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
Suppression of apoptosis R-HSA-9635465
Intracellular signaling by second messengers R-HSA-9006925
IRE1alpha activates chaperones R-HSA-381070
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Unfolded Protein Response (UPR) R-HSA-381119
Translation of Structural Proteins R-HSA-9694635
PIP3 activates AKT signaling R-HSA-1257604
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Disease R-HSA-1643685
XBP1(S) activates chaperone genes R-HSA-381038
Infectious disease R-HSA-5663205
Intracellular signaling by second messengers R-HSA-9006925
SARS-CoV-2 Infection R-HSA-9694516
Late SARS-CoV-2 Infection Events R-HSA-9772573
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
SARS-CoV-1 Infection R-HSA-9678108
Maturation of nucleoprotein R-HSA-9683610
Maturation of nucleoprotein R-HSA-9694631
PI3K/AKT Signaling in Cancer R-HSA-2219528
Infection with Mycobacterium tuberculosis R-HSA-9635486
AKT phosphorylates targets in the cytosol R-HSA-198323
SARS-CoV Infections R-HSA-9679506
Translation of Structural Proteins R-HSA-9683701
Suppression of apoptosis R-HSA-9635465
Response of Mtb to phagocytosis R-HSA-9637690
Maturation of nucleoprotein R-HSA-9694631
AKT phosphorylates targets in the cytosol R-HSA-198323
Infectious disease R-HSA-5663205
SARS-CoV-1 Infection R-HSA-9678108
Disease R-HSA-1643685
Translation of Structural Proteins R-HSA-9694635
Signal Transduction R-HSA-162582
SARS-CoV Infections R-HSA-9679506
IRE1alpha activates chaperones R-HSA-381070
Suppression of apoptosis R-HSA-9635465
PI3K/AKT Signaling in Cancer R-HSA-2219528
Response of Mtb to phagocytosis R-HSA-9637690
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Late SARS-CoV-2 Infection Events R-HSA-9772573
Unfolded Protein Response (UPR) R-HSA-381119
PIP3 activates AKT signaling R-HSA-1257604
Translation of Structural Proteins R-HSA-9683701
Maturation of nucleoprotein R-HSA-9683610
SARS-CoV-2 Infection R-HSA-9694516
Cellular responses to stress R-HSA-2262752
XBP1(S) activates chaperone genes R-HSA-381038
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular responses to stimuli R-HSA-8953897
Intracellular signaling by second messengers R-HSA-9006925

Expression Atlas ENSG00000105723
NCBI gene (formerly Entrezgene) 2931
GeneCards 4616
HGNC Symbol HGNC:4616
MIM gene 606784
UniProtKB Gene Name P49840
WikiGene 2931
Gene: FGFR2
Ensembl ID : ENSG00000066468
Description: fibroblast growth factor receptor 2
Gene Synonyms: BEK,CD332,CEK3,CFD1,ECT1,JWS,K-SAM,KGFR,TK14,TK25
27 APIs:
218 Possible Orthologues:

Activated point mutants of FGFR2 R-HSA-2033519
PI3K Cascade R-HSA-109704
FGFR2b ligand binding and activation R-HSA-190377
FGFR2 alternative splicing R-HSA-6803529
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FGFR2c ligand binding and activation R-HSA-190375
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR in disease R-HSA-1226099
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Insulin receptor R-HSA-74752
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by FGFR R-HSA-190236
Signaling by FGFR2 IIIa TM R-HSA-8851708
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by FGFR2 R-HSA-5654738
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 amplification mutants R-HSA-2023837
FGFR2 ligand binding and activation R-HSA-190241
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
FGFR2 mutant receptor activation R-HSA-1839126
Insulin receptor signalling cascade R-HSA-74751
SHC-mediated cascade:FGFR2 R-HSA-5654699
PIP3 activates AKT signaling R-HSA-1257604
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by FGFR2 fusions R-HSA-8853333
IRS-mediated signalling R-HSA-112399
Negative regulation of the PI3K/AKT network R-HSA-199418
Negative regulation of FGFR2 signaling R-HSA-5654727
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Disease R-HSA-1643685
Signaling by FGFR2 fusions R-HSA-8853333
IRS-mediated signalling R-HSA-112399
Signaling by FGFR2 in disease R-HSA-5655253
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
FGFR2c ligand binding and activation R-HSA-190375
Insulin receptor signalling cascade R-HSA-74751
FGFR2 ligand binding and activation R-HSA-190241
FGFR2b ligand binding and activation R-HSA-190377
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Downstream signaling of activated FGFR2 R-HSA-5654696
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IGF1R signaling cascade R-HSA-2428924
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR R-HSA-190236
PI3K Cascade R-HSA-109704
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR in disease R-HSA-1226099
Negative regulation of FGFR2 signaling R-HSA-5654727
Activated point mutants of FGFR2 R-HSA-2033519
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 R-HSA-5654738
FGFR2 mutant receptor activation R-HSA-1839126
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by FGFR2 IIIa TM R-HSA-8851708
IRS-related events triggered by IGF1R R-HSA-2428928
PI-3K cascade:FGFR2 R-HSA-5654695
FGFR2 alternative splicing R-HSA-6803529
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Activated point mutants of FGFR2 R-HSA-2033519
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling of activated FGFR2 R-HSA-5654696
FGFR2 alternative splicing R-HSA-6803529
FGFR2c ligand binding and activation R-HSA-190375
Signal Transduction R-HSA-162582
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by FGFR2 IIIa TM R-HSA-8851708
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 amplification mutants R-HSA-2023837
FGFR2 ligand binding and activation R-HSA-190241
Negative regulation of the PI3K/AKT network R-HSA-199418
FGFR2 mutant receptor activation R-HSA-1839126
PI3K Cascade R-HSA-109704
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
IRS-mediated signalling R-HSA-112399
Signaling by FGFR in disease R-HSA-1226099
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR R-HSA-190236
IGF1R signaling cascade R-HSA-2428924
FGFR2b ligand binding and activation R-HSA-190377
Disease R-HSA-1643685
Signaling by Insulin receptor R-HSA-74752
PI3K/AKT Signaling in Cancer R-HSA-2219528
Insulin receptor signalling cascade R-HSA-74751
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR2 in disease R-HSA-5655253
RAF/MAP kinase cascade R-HSA-5673001
FRS-mediated FGFR2 signaling R-HSA-5654700
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 in disease R-HSA-5655253
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FGFR2 ligand binding and activation R-HSA-190241
MAPK1/MAPK3 signaling R-HSA-5684996
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR2 IIIa TM R-HSA-8851708
Disease R-HSA-1643685
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2c ligand binding and activation R-HSA-190375
Signaling by FGFR R-HSA-190236
Downstream signaling of activated FGFR2 R-HSA-5654696
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR in disease R-HSA-1226099
PI3K Cascade R-HSA-109704
IRS-mediated signalling R-HSA-112399
Insulin receptor signalling cascade R-HSA-74751
IGF1R signaling cascade R-HSA-2428924
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR2 R-HSA-5654738
PIP3 activates AKT signaling R-HSA-1257604
FRS-mediated FGFR2 signaling R-HSA-5654700
SHC-mediated cascade:FGFR2 R-HSA-5654699
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FGFR2b ligand binding and activation R-HSA-190377
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by Insulin receptor R-HSA-74752
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI-3K cascade:FGFR2 R-HSA-5654695
IRS-related events triggered by IGF1R R-HSA-2428928
MAPK family signaling cascades R-HSA-5683057
IRS-mediated signalling R-HSA-112399
PIP3 activates AKT signaling R-HSA-1257604
Signaling by FGFR2 IIIa TM R-HSA-8851708
FGFR2 ligand binding and activation R-HSA-190241
PI3K Cascade R-HSA-109704
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by FGFR2 in disease R-HSA-5655253
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2b ligand binding and activation R-HSA-190377
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR2 amplification mutants R-HSA-2023837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Signaling by FGFR in disease R-HSA-1226099
FGFR2c ligand binding and activation R-HSA-190375
RAF/MAP kinase cascade R-HSA-5673001
PI3K/AKT Signaling in Cancer R-HSA-2219528
SHC-mediated cascade:FGFR2 R-HSA-5654699
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
FRS-mediated FGFR2 signaling R-HSA-5654700
Disease R-HSA-1643685
IRS-related events triggered by IGF1R R-HSA-2428928
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
FGFR2 alternative splicing R-HSA-6803529
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR R-HSA-190236
IGF1R signaling cascade R-HSA-2428924
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 in disease R-HSA-5655253
FGFR2c ligand binding and activation R-HSA-190375
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
Negative regulation of the PI3K/AKT network R-HSA-199418
FGFR2 ligand binding and activation R-HSA-190241
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
MAPK1/MAPK3 signaling R-HSA-5684996
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 amplification mutants R-HSA-2023837
IRS-related events triggered by IGF1R R-HSA-2428928
Negative regulation of FGFR2 signaling R-HSA-5654727
RAF/MAP kinase cascade R-HSA-5673001
IRS-mediated signalling R-HSA-112399
IGF1R signaling cascade R-HSA-2428924
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by FGFR2 IIIa TM R-HSA-8851708
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR in disease R-HSA-1226099
PI3K Cascade R-HSA-109704
MAPK family signaling cascades R-HSA-5683057
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Disease R-HSA-1643685
Downstream signaling of activated FGFR2 R-HSA-5654696
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR R-HSA-190236
Intracellular signaling by second messengers R-HSA-9006925
FRS-mediated FGFR2 signaling R-HSA-5654700
FGFR2 mutant receptor activation R-HSA-1839126
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2b ligand binding and activation R-HSA-190377
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Insulin receptor signalling cascade R-HSA-74751
IGF1R signaling cascade R-HSA-2428924
PIP3 activates AKT signaling R-HSA-1257604
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K Cascade R-HSA-109704
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR R-HSA-190236
Signaling by FGFR2 amplification mutants R-HSA-2023837
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2 mutant receptor activation R-HSA-1839126
Signal Transduction R-HSA-162582
FRS-mediated FGFR2 signaling R-HSA-5654700
IRS-mediated signalling R-HSA-112399
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 IIIa TM R-HSA-8851708
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR in disease R-HSA-1226099
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Negative regulation of FGFR2 signaling R-HSA-5654727
PI3K/AKT Signaling in Cancer R-HSA-2219528
Disease R-HSA-1643685
FGFR2c ligand binding and activation R-HSA-190375
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FGFR2 ligand binding and activation R-HSA-190241
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 in disease R-HSA-5655253
IRS-related events triggered by IGF1R R-HSA-2428928
FGFR2 alternative splicing R-HSA-6803529
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling of activated FGFR2 R-HSA-5654696
Insulin receptor signalling cascade R-HSA-74751
FGFR2b ligand binding and activation R-HSA-190377
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IGF1R signaling cascade R-HSA-2428924
Activated point mutants of FGFR2 R-HSA-2033519
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 amplification mutants R-HSA-2023837
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
SHC-mediated cascade:FGFR2 R-HSA-5654699
PIP3 activates AKT signaling R-HSA-1257604
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by FGFR2 fusions R-HSA-8853333
Downstream signaling of activated FGFR2 R-HSA-5654696
FGFR2c ligand binding and activation R-HSA-190375
Negative regulation of FGFR2 signaling R-HSA-5654727
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR2 IIIa TM R-HSA-8851708
Disease R-HSA-1643685
FGFR2 ligand binding and activation R-HSA-190241
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR R-HSA-190236
PI-3K cascade:FGFR2 R-HSA-5654695
FGFR2b ligand binding and activation R-HSA-190377
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR2 in disease R-HSA-5655253
IRS-mediated signalling R-HSA-112399
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR in disease R-HSA-1226099
IRS-related events triggered by IGF1R R-HSA-2428928
PI3K Cascade R-HSA-109704
FGFR2 alternative splicing R-HSA-6803529
Signal Transduction R-HSA-162582
FGFR2 mutant receptor activation R-HSA-1839126
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 in disease R-HSA-5655253
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by FGFR2 amplification mutants R-HSA-2023837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR in disease R-HSA-1226099
Disease R-HSA-1643685
Negative regulation of FGFR2 signaling R-HSA-5654727
PIP3 activates AKT signaling R-HSA-1257604
FGFR2 mutant receptor activation R-HSA-1839126
Signaling by FGFR2 IIIa TM R-HSA-8851708
Signaling by FGFR R-HSA-190236
Signal Transduction R-HSA-162582
FGFR2b ligand binding and activation R-HSA-190377
IRS-mediated signalling R-HSA-112399
FGFR2c ligand binding and activation R-HSA-190375
IGF1R signaling cascade R-HSA-2428924
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
IRS-related events triggered by IGF1R R-HSA-2428928
PI3K Cascade R-HSA-109704
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Insulin receptor R-HSA-74752
PI-3K cascade:FGFR2 R-HSA-5654695
Negative regulation of the PI3K/AKT network R-HSA-199418
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2 ligand binding and activation R-HSA-190241
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
SHC-mediated cascade:FGFR2 R-HSA-5654699
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 IIIa TM R-HSA-8851708
SHC-mediated cascade:FGFR2 R-HSA-5654699
FGFR2b ligand binding and activation R-HSA-190377
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 in disease R-HSA-5655253
IRS-related events triggered by IGF1R R-HSA-2428928
MAPK family signaling cascades R-HSA-5683057
FGFR2c ligand binding and activation R-HSA-190375
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR2 R-HSA-5654738
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR2 fusions R-HSA-8853333
Negative regulation of FGFR2 signaling R-HSA-5654727
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR R-HSA-190236
Activated point mutants of FGFR2 R-HSA-2033519
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Disease R-HSA-1643685
PI-3K cascade:FGFR2 R-HSA-5654695
MAPK1/MAPK3 signaling R-HSA-5684996
FRS-mediated FGFR2 signaling R-HSA-5654700
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
PI3K Cascade R-HSA-109704
Signaling by FGFR in disease R-HSA-1226099
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2 ligand binding and activation R-HSA-190241
FGFR2 alternative splicing R-HSA-6803529
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS-mediated signalling R-HSA-112399

Expression Atlas ENSG00000066468
LRG display in Ensembl gene LRG_994
NCBI gene (formerly Entrezgene) 2263
GeneCards 3689
HGNC Symbol HGNC:3689
MIM gene 176943
MIM morbid 614592
UniProtKB Gene Name S4R3B2
WikiGene 2263
Gene: PRKACB
Ensembl ID : ENSG00000142875
Description: protein kinase cAMP-activated catalytic subunit beta
Gene Synonyms: PKACB
1 APIs:
303 Possible Orthologues:

Disease R-HSA-1643685
Metabolism of lipids R-HSA-556833
Signal Transduction R-HSA-162582
Transport of small molecules R-HSA-382551
Leishmania parasite growth and survival R-HSA-9664433
Degradation of GLI1 by the proteasome R-HSA-5610780
Rap1 signalling R-HSA-392517
PLC beta mediated events R-HSA-112043
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Calmodulin induced events R-HSA-111933
DARPP-32 events R-HSA-180024
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Triglyceride metabolism R-HSA-8979227
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Immune System R-HSA-168256
Signaling by ROBO receptors R-HSA-376176
CD209 (DC-SIGN) signaling R-HSA-5621575
GPCR downstream signalling R-HSA-388396
Metabolism of carbohydrates R-HSA-71387
Glucagon signaling in metabolic regulation R-HSA-163359
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Degradation of GLI2 by the proteasome R-HSA-5610783
Leishmania infection R-HSA-9658195
Adaptive Immune System R-HSA-1280218
Glucose metabolism R-HSA-70326
VEGFA-VEGFR2 Pathway R-HSA-4420097
DAG and IP3 signaling R-HSA-1489509
HDL assembly R-HSA-8963896
PKA activation in glucagon signalling R-HSA-164378
Nervous system development R-HSA-9675108
Triglyceride catabolism R-HSA-163560
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
CaM pathway R-HSA-111997
Regulation of insulin secretion R-HSA-422356
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transmission across Chemical Synapses R-HSA-112315
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676
G-protein mediated events R-HSA-112040
G alpha (s) signalling events R-HSA-418555
Integration of energy metabolism R-HSA-163685
GPER1 signaling R-HSA-9634597
Plasma lipoprotein assembly R-HSA-8963898
Ca-dependent events R-HSA-111996
Metabolism R-HSA-1430728
Hedgehog 'off' state R-HSA-5610787
Hemostasis R-HSA-109582
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
Neuronal System R-HSA-112316
C-type lectin receptors (CLRs) R-HSA-5621481
Aquaporin-mediated transport R-HSA-445717
MAPK family signaling cascades R-HSA-5683057
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040
Infectious disease R-HSA-5663205
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720
Signaling by GPCR R-HSA-372790
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600
G alpha (i) signalling events R-HSA-418594
PKA activation R-HSA-163615
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358
PKA-mediated phosphorylation of CREB R-HSA-111931
Post NMDA receptor activation events R-HSA-438064
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
RET signaling R-HSA-8853659
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by VEGF R-HSA-194138
ROBO receptors bind AKAP5 R-HSA-9010642
Innate Immune System R-HSA-168249
Opioid Signalling R-HSA-111885
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Glycolysis R-HSA-70171
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Hedgehog R-HSA-5358351
GPER1 signaling R-HSA-9634597
DARPP-32 events R-HSA-180024
G-protein mediated events R-HSA-112040
PKA activation in glucagon signalling R-HSA-164378
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Hemostasis R-HSA-109582
Axon guidance R-HSA-422475
CD209 (DC-SIGN) signaling R-HSA-5621575
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Calmodulin induced events R-HSA-111933
Metabolism of carbohydrates R-HSA-71387
Metabolism of lipids R-HSA-556833
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720
Signaling by GPCR R-HSA-372790
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676
Signal Transduction R-HSA-162582
Post NMDA receptor activation events R-HSA-438064
ROBO receptors bind AKAP5 R-HSA-9010642
Ca-dependent events R-HSA-111996
Signaling by VEGF R-HSA-194138
Aquaporin-mediated transport R-HSA-445717
Triglyceride metabolism R-HSA-8979227
Leishmania infection R-HSA-9658195
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
C-type lectin receptors (CLRs) R-HSA-5621481
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Glycolysis R-HSA-70171
Glucose metabolism R-HSA-70326
PKA-mediated phosphorylation of CREB R-HSA-111931
Immune System R-HSA-168256
PLC beta mediated events R-HSA-112043
Degradation of GLI1 by the proteasome R-HSA-5610780
Plasma lipoprotein assembly R-HSA-8963898
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Transport of small molecules R-HSA-382551
MAPK family signaling cascades R-HSA-5683057
Transmission across Chemical Synapses R-HSA-112315
Triglyceride catabolism R-HSA-163560
Degradation of GLI2 by the proteasome R-HSA-5610783
DAG and IP3 signaling R-HSA-1489509
CaM pathway R-HSA-111997
HDL assembly R-HSA-8963896
Leishmania parasite growth and survival R-HSA-9664433
Rap1 signalling R-HSA-392517
Innate Immune System R-HSA-168249
G alpha (i) signalling events R-HSA-418594
Integration of energy metabolism R-HSA-163685
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358
Neuronal System R-HSA-112316
Metabolism R-HSA-1430728
Opioid Signalling R-HSA-111885
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
G alpha (s) signalling events R-HSA-418555
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600
Nervous system development R-HSA-9675108
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
GPCR downstream signalling R-HSA-388396
Regulation of insulin secretion R-HSA-422356
VEGFA-VEGFR2 Pathway R-HSA-4420097
PKA activation R-HSA-163615
MAPK6/MAPK4 signaling R-HSA-5687128
Glucagon signaling in metabolic regulation R-HSA-163359
Developmental Biology R-HSA-1266738
RET signaling R-HSA-8853659
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Intracellular signaling by second messengers R-HSA-9006925
Adaptive Immune System R-HSA-1280218
Hedgehog 'off' state R-HSA-5610787
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by Hedgehog R-HSA-5358351
Signaling by ROBO receptors R-HSA-376176
Disease R-HSA-1643685
Transmission across Chemical Synapses R-HSA-112315
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040
Integration of energy metabolism R-HSA-163685
Opioid Signalling R-HSA-111885
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Calmodulin induced events R-HSA-111933
G alpha (i) signalling events R-HSA-418594
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Glucagon signaling in metabolic regulation R-HSA-163359
Adaptive Immune System R-HSA-1280218
Aquaporin-mediated transport R-HSA-445717
Regulation of insulin secretion R-HSA-422356
Post NMDA receptor activation events R-HSA-438064
Glycolysis R-HSA-70171
G-protein mediated events R-HSA-112040
Glucose metabolism R-HSA-70326
DAG and IP3 signaling R-HSA-1489509
PLC beta mediated events R-HSA-112043
Signaling by ROBO receptors R-HSA-376176
VEGFA-VEGFR2 Pathway R-HSA-4420097
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600
Signaling by Hedgehog R-HSA-5358351
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Innate Immune System R-HSA-168249
PKA-mediated phosphorylation of CREB R-HSA-111931
Degradation of GLI2 by the proteasome R-HSA-5610783
FCGR3A-mediated IL10 synthesis R-HSA-9664323
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Disease R-HSA-1643685
Triglyceride metabolism R-HSA-8979227
PKA activation R-HSA-163615
MAPK family signaling cascades R-HSA-5683057
Infectious disease R-HSA-5663205
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676
Metabolism R-HSA-1430728
CaM pathway R-HSA-111997
Transport of small molecules R-HSA-382551
Degradation of GLI1 by the proteasome R-HSA-5610780
HDL assembly R-HSA-8963896
Signaling by GPCR R-HSA-372790
Plasma lipoprotein assembly R-HSA-8963898
Triglyceride catabolism R-HSA-163560
PKA activation in glucagon signalling R-HSA-164378
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of carbohydrates R-HSA-71387
Ca-dependent events R-HSA-111996
Neuronal System R-HSA-112316
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
ROBO receptors bind AKAP5 R-HSA-9010642
Intracellular signaling by second messengers R-HSA-9006925
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Axon guidance R-HSA-422475
RET signaling R-HSA-8853659
GPER1 signaling R-HSA-9634597
Nervous system development R-HSA-9675108
Rap1 signalling R-HSA-392517
Signaling by VEGF R-HSA-194138
CD209 (DC-SIGN) signaling R-HSA-5621575
Hemostasis R-HSA-109582
DARPP-32 events R-HSA-180024
Leishmania infection R-HSA-9658195
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of lipids R-HSA-556833
Leishmania parasite growth and survival R-HSA-9664433
C-type lectin receptors (CLRs) R-HSA-5621481
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358
Hedgehog 'off' state R-HSA-5610787
Signal Transduction R-HSA-162582
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Developmental Biology R-HSA-1266738
Immune System R-HSA-168256
Degradation of GLI1 by the proteasome R-HSA-5610780
ROBO receptors bind AKAP5 R-HSA-9010642
Disease R-HSA-1643685
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Integration of energy metabolism R-HSA-163685
Infectious disease R-HSA-5663205
Hedgehog 'off' state R-HSA-5610787
Transmission across Chemical Synapses R-HSA-112315
Ca-dependent events R-HSA-111996
Metabolism of lipids R-HSA-556833
G alpha (i) signalling events R-HSA-418594
Glycolysis R-HSA-70171
PKA activation R-HSA-163615
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Metabolism R-HSA-1430728
PLC beta mediated events R-HSA-112043
DARPP-32 events R-HSA-180024
Metabolism of carbohydrates R-HSA-71387
Triglyceride metabolism R-HSA-8979227
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358
Regulation of insulin secretion R-HSA-422356
CaM pathway R-HSA-111997
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
VEGFA-VEGFR2 Pathway R-HSA-4420097
Hemostasis R-HSA-109582
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Glucagon signaling in metabolic regulation R-HSA-163359
PKA-mediated phosphorylation of CREB R-HSA-111931
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720
PKA activation in glucagon signalling R-HSA-164378
DAG and IP3 signaling R-HSA-1489509
Calmodulin induced events R-HSA-111933
Adaptive Immune System R-HSA-1280218
MAPK family signaling cascades R-HSA-5683057
Glucose metabolism R-HSA-70326
Intracellular signaling by second messengers R-HSA-9006925
Innate Immune System R-HSA-168249
Signaling by ROBO receptors R-HSA-376176
Immune System R-HSA-168256
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Post NMDA receptor activation events R-HSA-438064
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by VEGF R-HSA-194138
GPCR downstream signalling R-HSA-388396
Leishmania infection R-HSA-9658195
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
RET signaling R-HSA-8853659
Rap1 signalling R-HSA-392517
Opioid Signalling R-HSA-111885
MAPK6/MAPK4 signaling R-HSA-5687128
Neuronal System R-HSA-112316
Developmental Biology R-HSA-1266738
C-type lectin receptors (CLRs) R-HSA-5621481
CD209 (DC-SIGN) signaling R-HSA-5621575
Plasma lipoprotein assembly R-HSA-8963898
Leishmania parasite growth and survival R-HSA-9664433
Signaling by GPCR R-HSA-372790
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Aquaporin-mediated transport R-HSA-445717
HDL assembly R-HSA-8963896
Triglyceride catabolism R-HSA-163560
Signaling by Hedgehog R-HSA-5358351
G alpha (s) signalling events R-HSA-418555
G-protein mediated events R-HSA-112040
Transport of small molecules R-HSA-382551
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
GPER1 signaling R-HSA-9634597
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Infectious disease R-HSA-5663205
Opioid Signalling R-HSA-111885
Developmental Biology R-HSA-1266738
Leishmania infection R-HSA-9658195
MAPK family signaling cascades R-HSA-5683057
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Neuronal System R-HSA-112316
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
DAG and IP3 signaling R-HSA-1489509
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Signaling by VEGF R-HSA-194138
Triglyceride metabolism R-HSA-8979227
Metabolism of lipids R-HSA-556833
Triglyceride catabolism R-HSA-163560
Glycolysis R-HSA-70171
Metabolism of carbohydrates R-HSA-71387
C-type lectin receptors (CLRs) R-HSA-5621481
Integration of energy metabolism R-HSA-163685
Post NMDA receptor activation events R-HSA-438064
Hedgehog 'off' state R-HSA-5610787
CaM pathway R-HSA-111997
G-protein mediated events R-HSA-112040
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720
Transmission across Chemical Synapses R-HSA-112315
Plasma lipoprotein assembly R-HSA-8963898
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G alpha (s) signalling events R-HSA-418555
Rap1 signalling R-HSA-392517
PKA activation in glucagon signalling R-HSA-164378
GPCR downstream signalling R-HSA-388396
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600
PKA-mediated phosphorylation of CREB R-HSA-111931
Leishmania parasite growth and survival R-HSA-9664433
G alpha (i) signalling events R-HSA-418594
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358
Factors involved in megakaryocyte development and platelet production R-HSA-983231
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Intracellular signaling by second messengers R-HSA-9006925
GPER1 signaling R-HSA-9634597
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676
ROBO receptors bind AKAP5 R-HSA-9010642
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Innate Immune System R-HSA-168249
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by ROBO receptors R-HSA-376176
Axon guidance R-HSA-422475
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040
MAPK6/MAPK4 signaling R-HSA-5687128
Hemostasis R-HSA-109582
Regulation of insulin secretion R-HSA-422356
Signal Transduction R-HSA-162582
DARPP-32 events R-HSA-180024
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
CD209 (DC-SIGN) signaling R-HSA-5621575
Ca-dependent events R-HSA-111996
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Degradation of GLI1 by the proteasome R-HSA-5610780
Adaptive Immune System R-HSA-1280218
HDL assembly R-HSA-8963896
RET signaling R-HSA-8853659
Immune System R-HSA-168256
Aquaporin-mediated transport R-HSA-445717
Signaling by Hedgehog R-HSA-5358351
Calmodulin induced events R-HSA-111933
PLC beta mediated events R-HSA-112043
Glucose metabolism R-HSA-70326
Glucagon signaling in metabolic regulation R-HSA-163359
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by GPCR R-HSA-372790
Metabolism R-HSA-1430728
PKA activation R-HSA-163615
Degradation of GLI2 by the proteasome R-HSA-5610783
GPCR downstream signalling R-HSA-388396
Integration of energy metabolism R-HSA-163685
Innate Immune System R-HSA-168249
Axon guidance R-HSA-422475
MAPK family signaling cascades R-HSA-5683057
Degradation of GLI1 by the proteasome R-HSA-5610780
ROBO receptors bind AKAP5 R-HSA-9010642
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Ca-dependent events R-HSA-111996
Opioid Signalling R-HSA-111885
G-protein mediated events R-HSA-112040
Intracellular signaling by second messengers R-HSA-9006925
Metabolism R-HSA-1430728
Glucagon signaling in metabolic regulation R-HSA-163359
Signal Transduction R-HSA-162582
Glucose metabolism R-HSA-70326
RET signaling R-HSA-8853659
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Transmission across Chemical Synapses R-HSA-112315
Leishmania parasite growth and survival R-HSA-9664433
PKA activation in glucagon signalling R-HSA-164378
Hedgehog 'off' state R-HSA-5610787
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Hemostasis R-HSA-109582
VEGFA-VEGFR2 Pathway R-HSA-4420097
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Triglyceride metabolism R-HSA-8979227
CD209 (DC-SIGN) signaling R-HSA-5621575
Glycolysis R-HSA-70171
MAPK6/MAPK4 signaling R-HSA-5687128
DARPP-32 events R-HSA-180024
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of carbohydrates R-HSA-71387
Neuronal System R-HSA-112316
Signaling by ROBO receptors R-HSA-376176
PKA activation R-HSA-163615
Calmodulin induced events R-HSA-111933
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Immune System R-HSA-168256
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040
GPER1 signaling R-HSA-9634597
Developmental Biology R-HSA-1266738
Transport of small molecules R-HSA-382551
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI2 by the proteasome R-HSA-5610783
Aquaporin-mediated transport R-HSA-445717
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Rap1 signalling R-HSA-392517
Signaling by GPCR R-HSA-372790
Signaling by VEGF R-HSA-194138
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G alpha (s) signalling events R-HSA-418555
Triglyceride catabolism R-HSA-163560
HDL assembly R-HSA-8963896
Adaptive Immune System R-HSA-1280218
Regulation of insulin secretion R-HSA-422356
Leishmania infection R-HSA-9658195
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Metabolism of lipids R-HSA-556833
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Post NMDA receptor activation events R-HSA-438064
DAG and IP3 signaling R-HSA-1489509
PLC beta mediated events R-HSA-112043
G alpha (i) signalling events R-HSA-418594
Nervous system development R-HSA-9675108
Plasma lipoprotein assembly R-HSA-8963898
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600
CaM pathway R-HSA-111997
PKA-mediated phosphorylation of CREB R-HSA-111931
Factors involved in megakaryocyte development and platelet production R-HSA-983231
PLC beta mediated events R-HSA-112043
Innate Immune System R-HSA-168249
CaM pathway R-HSA-111997
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358
Neuronal System R-HSA-112316
C-type lectin receptors (CLRs) R-HSA-5621481
CD209 (DC-SIGN) signaling R-HSA-5621575
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Infectious disease R-HSA-5663205
Hedgehog 'off' state R-HSA-5610787
DAG and IP3 signaling R-HSA-1489509
G alpha (i) signalling events R-HSA-418594
Rap1 signalling R-HSA-392517
Triglyceride metabolism R-HSA-8979227
Post NMDA receptor activation events R-HSA-438064
GPER1 signaling R-HSA-9634597
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of insulin secretion R-HSA-422356
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Axon guidance R-HSA-422475
G-protein mediated events R-HSA-112040
RET signaling R-HSA-8853659
G alpha (s) signalling events R-HSA-418555
Ca-dependent events R-HSA-111996
Glycolysis R-HSA-70171
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
GPCR downstream signalling R-HSA-388396
Calmodulin induced events R-HSA-111933
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Metabolism of carbohydrates R-HSA-71387
ROBO receptors bind AKAP5 R-HSA-9010642
Metabolism R-HSA-1430728
Glucagon signaling in metabolic regulation R-HSA-163359
Hemostasis R-HSA-109582
Aquaporin-mediated transport R-HSA-445717
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by ROBO receptors R-HSA-376176
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720
PKA activation R-HSA-163615
Nervous system development R-HSA-9675108
PKA-mediated phosphorylation of CREB R-HSA-111931
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Hedgehog R-HSA-5358351
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
VEGFA-VEGFR2 Pathway R-HSA-4420097
HDL assembly R-HSA-8963896
Intracellular signaling by second messengers R-HSA-9006925
Immune System R-HSA-168256
Glucose metabolism R-HSA-70326
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600
Transport of small molecules R-HSA-382551
Leishmania infection R-HSA-9658195
Plasma lipoprotein assembly R-HSA-8963898
Signaling by VEGF R-HSA-194138
Developmental Biology R-HSA-1266738
Metabolism of lipids R-HSA-556833
Signaling by GPCR R-HSA-372790
DARPP-32 events R-HSA-180024
Degradation of GLI2 by the proteasome R-HSA-5610783
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Integration of energy metabolism R-HSA-163685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Triglyceride catabolism R-HSA-163560
Transmission across Chemical Synapses R-HSA-112315
Leishmania parasite growth and survival R-HSA-9664433
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676
Adaptive Immune System R-HSA-1280218
PKA activation in glucagon signalling R-HSA-164378
Opioid Signalling R-HSA-111885
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040
Neuronal System R-HSA-112316
Infectious disease R-HSA-5663205
Transport of small molecules R-HSA-382551
PKA activation in glucagon signalling R-HSA-164378
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
GPER1 signaling R-HSA-9634597
Metabolism of carbohydrates R-HSA-71387
Post NMDA receptor activation events R-HSA-438064
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600
Aquaporin-mediated transport R-HSA-445717
Triglyceride metabolism R-HSA-8979227
Hemostasis R-HSA-109582
Transmission across Chemical Synapses R-HSA-112315
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by VEGF R-HSA-194138
RET signaling R-HSA-8853659
G alpha (s) signalling events R-HSA-418555
Signaling by ROBO receptors R-HSA-376176
Glucose metabolism R-HSA-70326
Innate Immune System R-HSA-168249
HDL assembly R-HSA-8963896
Triglyceride catabolism R-HSA-163560
Signaling by GPCR R-HSA-372790
Opioid Signalling R-HSA-111885
Metabolism of lipids R-HSA-556833
Signal Transduction R-HSA-162582
Signaling by Hedgehog R-HSA-5358351
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Immune System R-HSA-168256
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720
PKA activation R-HSA-163615
Glycolysis R-HSA-70171
PKA-mediated phosphorylation of CREB R-HSA-111931
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358
MAPK6/MAPK4 signaling R-HSA-5687128
Leishmania infection R-HSA-9658195
Ca-dependent events R-HSA-111996
Regulation of insulin secretion R-HSA-422356
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040
Integration of energy metabolism R-HSA-163685
Axon guidance R-HSA-422475
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'off' state R-HSA-5610787
VEGFA-VEGFR2 Pathway R-HSA-4420097
Nervous system development R-HSA-9675108
CD209 (DC-SIGN) signaling R-HSA-5621575
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Degradation of GLI1 by the proteasome R-HSA-5610780
Calmodulin induced events R-HSA-111933
MAPK family signaling cascades R-HSA-5683057
Degradation of GLI2 by the proteasome R-HSA-5610783
G-protein mediated events R-HSA-112040
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676
Rap1 signalling R-HSA-392517
Disease R-HSA-1643685
Plasma lipoprotein assembly R-HSA-8963898
ROBO receptors bind AKAP5 R-HSA-9010642
CaM pathway R-HSA-111997
DAG and IP3 signaling R-HSA-1489509
Metabolism R-HSA-1430728
Adaptive Immune System R-HSA-1280218
FCGR3A-mediated IL10 synthesis R-HSA-9664323
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
DARPP-32 events R-HSA-180024
Glucagon signaling in metabolic regulation R-HSA-163359
Leishmania parasite growth and survival R-HSA-9664433
PLC beta mediated events R-HSA-112043
C-type lectin receptors (CLRs) R-HSA-5621481

Expression Atlas ENSG00000142875
NCBI gene (formerly Entrezgene) 5567
GeneCards 9381
HGNC Symbol HGNC:9381
MIM gene 176892
MIM morbid 619143
UniProtKB Gene Name P22694
WikiGene 5567
Gene: MAPK3
Ensembl ID : ENSG00000102882
Description: mitogen-activated protein kinase 3
Gene Synonyms: ERK1,P44ERK1,P44MAPK,PRKM3
6 APIs:
199 Possible Orthologues:

ERK/MAPK targets R-HSA-198753
M Phase R-HSA-68886
Disease R-HSA-1643685
Signaling by RAS mutants R-HSA-6802949
Signaling by NODAL R-HSA-1181150
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
G alpha (q) signalling events R-HSA-416476
ESR-mediated signaling R-HSA-8939211
Signal attenuation R-HSA-74749
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Growth hormone receptor signaling R-HSA-982772
GPCR downstream signalling R-HSA-388396
Negative regulation of MAPK pathway R-HSA-5675221
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR3 R-HSA-5654741
Signaling by TGF-beta Receptor Complex R-HSA-170834
ISG15 antiviral mechanism R-HSA-1169408
RUNX2 regulates bone development R-HSA-8941326
Toll-like Receptor Cascades R-HSA-168898
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Negative regulation of FGFR3 signaling R-HSA-5654732
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Disease R-HSA-1643685
Signaling by Nuclear Receptors R-HSA-9006931
Activation of the AP-1 family of transcription factors R-HSA-450341
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by FGFR1 R-HSA-5654736
Signaling by Activin R-HSA-1502540
Signaling by NTRKs R-HSA-166520
L1CAM interactions R-HSA-373760
MAPK3 (ERK1) activation R-HSA-110056
Interferon Signaling R-HSA-913531
Frs2-mediated activation R-HSA-170968
Signalling to ERKs R-HSA-187687
RNA Polymerase I Promoter Opening R-HSA-73728
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ALK in cancer R-HSA-9700206
Cell Cycle, Mitotic R-HSA-69278
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
NCAM signaling for neurite out-growth R-HSA-375165
Cellular responses to stress R-HSA-2262752
Signaling downstream of RAS mutants R-HSA-9649948
Negative regulation of the PI3K/AKT network R-HSA-199418
MyD88 cascade initiated on plasma membrane R-HSA-975871
Formation of apoptosome R-HSA-111458
ERK/MAPK targets R-HSA-198753
Response of Mtb to phagocytosis R-HSA-9637690
M Phase R-HSA-68886
Post NMDA receptor activation events R-HSA-438064
Transcriptional regulation by RUNX2 R-HSA-8878166
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Suppression of apoptosis R-HSA-9635465
Cellular Senescence R-HSA-2559583
Nervous system development R-HSA-9675108
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Hemostasis R-HSA-109582
Intrinsic Pathway for Apoptosis R-HSA-109606
RNA Polymerase I Promoter Clearance R-HSA-73854
Regulation of the apoptosome activity R-HSA-9627069
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-17 signaling R-HSA-448424
Innate Immune System R-HSA-168249
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Neuronal System R-HSA-112316
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF-independent MAPK1/3 activation R-HSA-112409
Leishmania phagocytosis R-HSA-9664417
MAPK family signaling cascades R-HSA-5683057
Generic Transcription Pathway R-HSA-212436
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Immune System R-HSA-168256
Signaling by TGFB family members R-HSA-9006936
Signal transduction by L1 R-HSA-445144
Signaling by FGFR4 R-HSA-5654743
Oxidative Stress Induced Senescence R-HSA-2559580
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Cytochrome c-mediated apoptotic response R-HSA-111461
MAP kinase activation R-HSA-450294
Insulin receptor signalling cascade R-HSA-74751
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Insulin receptor R-HSA-74752
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RNA Polymerase I Transcription R-HSA-73864
MyD88-independent TLR4 cascade R-HSA-166166
Transmission across Chemical Synapses R-HSA-112315
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by Interleukins R-HSA-449147
Signaling by FGFR2 R-HSA-5654738
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Leishmania infection R-HSA-9658195
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Apoptotic factor-mediated response R-HSA-111471
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by GPCR R-HSA-372790
RHO GTPase Effectors R-HSA-195258
Oncogene Induced Senescence R-HSA-2559585
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
PTEN Regulation R-HSA-6807070
Developmental Biology R-HSA-1266738
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Cellular response to heat stress R-HSA-3371556
NPAS4 regulates expression of target genes R-HSA-9768919
ERKs are inactivated R-HSA-202670
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Programmed Cell Death R-HSA-5357801
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MAP2K and MAPK activation R-HSA-5674135
RAF/MAP kinase cascade R-HSA-5673001
FCGR3A-mediated phagocytosis R-HSA-9664422
Negative regulation of FGFR1 signaling R-HSA-5654726
Parasite infection R-HSA-9664407
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
Signaling by MAP2K mutants R-HSA-9652169
Axon guidance R-HSA-422475
Infection with Mycobacterium tuberculosis R-HSA-9635486
Oncogenic MAPK signaling R-HSA-6802957
Apoptosis R-HSA-109581
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cell Cycle R-HSA-1640170
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Prolonged ERK activation events R-HSA-169893
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Negative regulation of FGFR4 signaling R-HSA-5654733
FCERI mediated MAPK activation R-HSA-2871796
Infectious disease R-HSA-5663205
Negative regulation of FGFR2 signaling R-HSA-5654727
Mitotic Prophase R-HSA-68875
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Signaling by FGFR R-HSA-190236
Transcriptional Regulation by NPAS4 R-HSA-9634815
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by NTRK1 (TRKA) R-HSA-187037
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
RSK activation R-HSA-444257
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Frs2-mediated activation R-HSA-170968
Cell Cycle, Mitotic R-HSA-69278
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by RAS mutants R-HSA-6802949
Interleukin-17 signaling R-HSA-448424
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Signaling by GPCR R-HSA-372790
Growth hormone receptor signaling R-HSA-982772
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by FGFR3 R-HSA-5654741
Suppression of apoptosis R-HSA-9635465
Transcriptional regulation by RUNX2 R-HSA-8878166
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
M Phase R-HSA-68886
Cellular response to heat stress R-HSA-3371556
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RSK activation R-HSA-444257
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by TGFB family members R-HSA-9006936
Signal transduction by L1 R-HSA-445144
FCGR3A-mediated phagocytosis R-HSA-9664422
Response of Mtb to phagocytosis R-HSA-9637690
Regulation of PTEN gene transcription R-HSA-8943724
Negative feedback regulation of MAPK pathway R-HSA-5674499
MAP2K and MAPK activation R-HSA-5674135
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Rho GTPases R-HSA-194315
Signaling by Insulin receptor R-HSA-74752
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Axon guidance R-HSA-422475
Programmed Cell Death R-HSA-5357801
NPAS4 regulates expression of target genes R-HSA-9768919
Neuronal System R-HSA-112316
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Hemostasis R-HSA-109582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Immune System R-HSA-168256
Cytochrome c-mediated apoptotic response R-HSA-111461
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal attenuation R-HSA-74749
Formation of apoptosome R-HSA-111458
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by ALK in cancer R-HSA-9700206
Signaling by Nuclear Receptors R-HSA-9006931
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cellular Senescence R-HSA-2559583
Signaling by MAP2K mutants R-HSA-9652169
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Transmission across Chemical Synapses R-HSA-112315
Signaling by FGFR R-HSA-190236
FCERI mediated MAPK activation R-HSA-2871796
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Cellular responses to stress R-HSA-2262752
Signaling by FGFR2 R-HSA-5654738
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
ERK/MAPK targets R-HSA-198753
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by NTRKs R-HSA-166520
Transcriptional Regulation by NPAS4 R-HSA-9634815
GPCR downstream signalling R-HSA-388396
MyD88-independent TLR4 cascade R-HSA-166166
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
PTEN Regulation R-HSA-6807070
Cell Cycle R-HSA-1640170
Negative regulation of FGFR1 signaling R-HSA-5654726
L1CAM interactions R-HSA-373760
Negative regulation of FGFR3 signaling R-HSA-5654732
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signalling to ERKs R-HSA-187687
Post NMDA receptor activation events R-HSA-438064
Oncogenic MAPK signaling R-HSA-6802957
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Interferon Signaling R-HSA-913531
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
RNA Polymerase I Promoter Opening R-HSA-73728
Activation of the AP-1 family of transcription factors R-HSA-450341
RNA Polymerase I Promoter Clearance R-HSA-73854
ERKs are inactivated R-HSA-202670
MyD88 dependent cascade initiated on endosome R-HSA-975155
ESR-mediated signaling R-HSA-8939211
Negative regulation of FGFR4 signaling R-HSA-5654733
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Activin R-HSA-1502540
Signaling by NTRK1 (TRKA) R-HSA-187037
Gene expression (Transcription) R-HSA-74160
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Negative regulation of FGFR2 signaling R-HSA-5654727
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK family signaling cascades R-HSA-5683057
Signaling by Interleukins R-HSA-449147
Insulin receptor signalling cascade R-HSA-74751
G alpha (q) signalling events R-HSA-416476
Signaling by NODAL R-HSA-1181150
PIP3 activates AKT signaling R-HSA-1257604
Regulation of the apoptosome activity R-HSA-9627069
Signaling by FGFR4 R-HSA-5654743
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK1/MAPK3 signaling R-HSA-5684996
NCAM signaling for neurite out-growth R-HSA-375165
Oncogene Induced Senescence R-HSA-2559585
Apoptosis R-HSA-109581
RNA Polymerase I Transcription R-HSA-73864
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Intrinsic Pathway for Apoptosis R-HSA-109606
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Parasite infection R-HSA-9664407
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Infection with Mycobacterium tuberculosis R-HSA-9635486
RHO GTPase Effectors R-HSA-195258
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Innate Immune System R-HSA-168249
Negative regulation of MAPK pathway R-HSA-5675221
Spry regulation of FGF signaling R-HSA-1295596
Leishmania phagocytosis R-HSA-9664417
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by FGFR1 R-HSA-5654736
MAP kinase activation R-HSA-450294
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by ALK fusions and activated point mutants R-HSA-9725370
ISG15 antiviral mechanism R-HSA-1169408
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Cytokine Signaling in Immune system R-HSA-1280215
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Negative regulation of the PI3K/AKT network R-HSA-199418
Toll-like Receptor Cascades R-HSA-168898
RAF/MAP kinase cascade R-HSA-5673001
Leishmania infection R-HSA-9658195
Generic Transcription Pathway R-HSA-212436
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Apoptotic factor-mediated response R-HSA-111471
MAPK3 (ERK1) activation R-HSA-110056
Platelet activation, signaling and aggregation R-HSA-76002
RUNX2 regulates bone development R-HSA-8941326
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Prolonged ERK activation events R-HSA-169893
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Growth hormone receptor signaling R-HSA-982772
MyD88 cascade initiated on plasma membrane R-HSA-975871
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
ISG15 antiviral mechanism R-HSA-1169408
Negative regulation of FGFR4 signaling R-HSA-5654733
Platelet activation, signaling and aggregation R-HSA-76002
RNA Polymerase I Promoter Opening R-HSA-73728
Parasite infection R-HSA-9664407
Axon guidance R-HSA-422475
RNA Polymerase I Promoter Clearance R-HSA-73854
Negative feedback regulation of MAPK pathway R-HSA-5674499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Prolonged ERK activation events R-HSA-169893
Toll-like Receptor Cascades R-HSA-168898
Signal transduction by L1 R-HSA-445144
Cellular Senescence R-HSA-2559583
NCAM signaling for neurite out-growth R-HSA-375165
L1CAM interactions R-HSA-373760
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Gene expression (Transcription) R-HSA-74160
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Signaling by NTRK1 (TRKA) R-HSA-187037
Cell Cycle R-HSA-1640170
Formation of apoptosome R-HSA-111458
Interleukin-17 signaling R-HSA-448424
Transcriptional regulation by RUNX2 R-HSA-8878166
NPAS4 regulates expression of target genes R-HSA-9768919
Hemostasis R-HSA-109582
Cellular responses to stimuli R-HSA-8953897
RAF-independent MAPK1/3 activation R-HSA-112409
Signalling to ERKs R-HSA-187687
Signaling by FGFR2 R-HSA-5654738
Negative regulation of MAPK pathway R-HSA-5675221
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Transmission across Chemical Synapses R-HSA-112315
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signaling by Insulin receptor R-HSA-74752
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Cytokine Signaling in Immune system R-HSA-1280215
ERK/MAPK targets R-HSA-198753
Signaling by Activin R-HSA-1502540
Interferon Signaling R-HSA-913531
Signaling by GPCR R-HSA-372790
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stress R-HSA-2262752
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Rho GTPases R-HSA-194315
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Transcriptional Regulation by NPAS4 R-HSA-9634815
RHO GTPase Effectors R-HSA-195258
Signal attenuation R-HSA-74749
Oncogenic MAPK signaling R-HSA-6802957
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling downstream of RAS mutants R-HSA-9649948
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAP kinase activation R-HSA-450294
Signaling by RAS mutants R-HSA-6802949
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Leishmania infection R-HSA-9658195
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by FGFR4 R-HSA-5654743
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by NODAL R-HSA-1181150
RUNX2 regulates bone development R-HSA-8941326
ERKs are inactivated R-HSA-202670
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by MAP2K mutants R-HSA-9652169
Signaling by FGFR1 R-HSA-5654736
Signaling by TGF-beta Receptor Complex R-HSA-170834
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Extra-nuclear estrogen signaling R-HSA-9009391
Nervous system development R-HSA-9675108
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Oncogene Induced Senescence R-HSA-2559585
Cell Cycle, Mitotic R-HSA-69278
Disease R-HSA-1643685
Signaling by FGFR3 R-HSA-5654741
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
PIP3 activates AKT signaling R-HSA-1257604
ESR-mediated signaling R-HSA-8939211
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RSK activation R-HSA-444257
Immune System R-HSA-168256
RAF/MAP kinase cascade R-HSA-5673001
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by NTRKs R-HSA-166520
Apoptotic factor-mediated response R-HSA-111471
Negative regulation of FGFR1 signaling R-HSA-5654726
Leishmania phagocytosis R-HSA-9664417
Programmed Cell Death R-HSA-5357801
Signaling by TGFB family members R-HSA-9006936
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Innate Immune System R-HSA-168249
Neuronal System R-HSA-112316
Oxidative Stress Induced Senescence R-HSA-2559580
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RNA Polymerase II Transcription R-HSA-73857
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Cytochrome c-mediated apoptotic response R-HSA-111461
M Phase R-HSA-68886
Post NMDA receptor activation events R-HSA-438064
G alpha (q) signalling events R-HSA-416476
Spry regulation of FGF signaling R-HSA-1295596
FCERI mediated MAPK activation R-HSA-2871796
PTEN Regulation R-HSA-6807070
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Cellular response to heat stress R-HSA-3371556
Suppression of apoptosis R-HSA-9635465
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Response of Mtb to phagocytosis R-HSA-9637690
MAPK3 (ERK1) activation R-HSA-110056
Signaling by RAF1 mutants R-HSA-9656223
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MAP2K and MAPK activation R-HSA-5674135
Signaling by ALK in cancer R-HSA-9700206
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR R-HSA-190236
Intracellular signaling by second messengers R-HSA-9006925
Regulation of the apoptosome activity R-HSA-9627069
Infectious disease R-HSA-5663205
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
RNA Polymerase I Transcription R-HSA-73864
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Negative regulation of FGFR2 signaling R-HSA-5654727
FCGR3A-mediated phagocytosis R-HSA-9664422
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Developmental Biology R-HSA-1266738
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Apoptosis R-HSA-109581
Signaling by ALK fusions and activated point mutants R-HSA-9725370
MAPK family signaling cascades R-HSA-5683057
Frs2-mediated activation R-HSA-170968
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
Mitotic Prophase R-HSA-68875
Negative regulation of the PI3K/AKT network R-HSA-199418
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Regulation of the apoptosome activity R-HSA-9627069
Signaling by RAF1 mutants R-HSA-9656223
Parasite infection R-HSA-9664407
Signaling by NTRKs R-HSA-166520
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Generic Transcription Pathway R-HSA-212436
Signaling by NODAL R-HSA-1181150
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
FCGR3A-mediated phagocytosis R-HSA-9664422
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Apoptosis R-HSA-109581
Oncogenic MAPK signaling R-HSA-6802957
Signaling by MAP2K mutants R-HSA-9652169
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Signaling by FGFR4 R-HSA-5654743
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Apoptotic factor-mediated response R-HSA-111471
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by FGFR2 R-HSA-5654738
Negative feedback regulation of MAPK pathway R-HSA-5674499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NCAM signaling for neurite out-growth R-HSA-375165
RNA Polymerase I Transcription R-HSA-73864
Cellular response to heat stress R-HSA-3371556
Neuronal System R-HSA-112316
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MyD88 cascade initiated on plasma membrane R-HSA-975871
RNA Polymerase I Promoter Clearance R-HSA-73854
Cell Cycle, Mitotic R-HSA-69278
RSK activation R-HSA-444257
Programmed Cell Death R-HSA-5357801
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signal transduction by L1 R-HSA-445144
Infectious disease R-HSA-5663205
Formation of apoptosome R-HSA-111458
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RUNX2 regulates osteoblast differentiation R-HSA-8940973
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by Insulin receptor R-HSA-74752
Regulation of PTEN gene transcription R-HSA-8943724
Interferon Signaling R-HSA-913531
Oxidative Stress Induced Senescence R-HSA-2559580
NPAS4 regulates expression of target genes R-HSA-9768919
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling downstream of RAS mutants R-HSA-9649948
Frs2-mediated activation R-HSA-170968
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 dependent cascade initiated on endosome R-HSA-975155
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
MAP kinase activation R-HSA-450294
RNA Polymerase I Promoter Opening R-HSA-73728
Signaling by BRAF and RAF1 fusions R-HSA-6802952
ISG15 antiviral mechanism R-HSA-1169408
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
ERKs are inactivated R-HSA-202670
Leishmania phagocytosis R-HSA-9664417
Leishmania infection R-HSA-9658195
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FGFR R-HSA-190236
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
L1CAM interactions R-HSA-373760
Insulin receptor signalling cascade R-HSA-74751
MAPK family signaling cascades R-HSA-5683057
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular responses to stimuli R-HSA-8953897
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signal attenuation R-HSA-74749
Intracellular signaling by second messengers R-HSA-9006925
Growth hormone receptor signaling R-HSA-982772
Signaling by NTRK1 (TRKA) R-HSA-187037
Prolonged ERK activation events R-HSA-169893
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAP2K and MAPK activation R-HSA-5674135
RAF/MAP kinase cascade R-HSA-5673001
Hemostasis R-HSA-109582
Toll-like Receptor Cascades R-HSA-168898
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by Rho GTPases R-HSA-194315
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Axon guidance R-HSA-422475
MAPK3 (ERK1) activation R-HSA-110056
Signaling by FGFR3 R-HSA-5654741
ESR-mediated signaling R-HSA-8939211
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
M Phase R-HSA-68886
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RHO GTPase Effectors R-HSA-195258
Mitotic Prophase R-HSA-68875
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by RAS mutants R-HSA-6802949
Platelet activation, signaling and aggregation R-HSA-76002
Innate Immune System R-HSA-168249
Post NMDA receptor activation events R-HSA-438064
Negative regulation of FGFR3 signaling R-HSA-5654732
Oncogene Induced Senescence R-HSA-2559585
Negative regulation of FGFR2 signaling R-HSA-5654727
Signalling to ERKs R-HSA-187687
Cellular Senescence R-HSA-2559583
Signaling by ALK in cancer R-HSA-9700206
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Activin R-HSA-1502540
Transcriptional regulation by RUNX2 R-HSA-8878166
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by FGFR1 R-HSA-5654736
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Interleukins R-HSA-449147
Negative regulation of MAPK pathway R-HSA-5675221
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Transmission across Chemical Synapses R-HSA-112315
FCERI mediated MAPK activation R-HSA-2871796
Suppression of apoptosis R-HSA-9635465
RUNX2 regulates bone development R-HSA-8941326
Signaling by TGF-beta Receptor Complex R-HSA-170834
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Response of Mtb to phagocytosis R-HSA-9637690
Transcriptional Regulation by NPAS4 R-HSA-9634815
RAF-independent MAPK1/3 activation R-HSA-112409
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
ERK/MAPK targets R-HSA-198753
Signaling by TGFB family members R-HSA-9006936
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Spry regulation of FGF signaling R-HSA-1295596
PIP3 activates AKT signaling R-HSA-1257604
Activation of the AP-1 family of transcription factors R-HSA-450341
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
RNA Polymerase II Transcription R-HSA-73857
Extra-nuclear estrogen signaling R-HSA-9009391
Interleukin-17 signaling R-HSA-448424
FCERI mediated MAPK activation R-HSA-2871796
Developmental Biology R-HSA-1266738
Signaling by NTRK1 (TRKA) R-HSA-187037
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR4 signaling R-HSA-5654733
Prolonged ERK activation events R-HSA-169893
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cellular responses to stress R-HSA-2262752
Signaling by GPCR R-HSA-372790
Negative feedback regulation of MAPK pathway R-HSA-5674499
RNA Polymerase I Transcription R-HSA-73864
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by TGFB family members R-HSA-9006936
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll-like Receptor Cascades R-HSA-168898
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
M Phase R-HSA-68886
Signaling by FGFR4 R-HSA-5654743
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Apoptosis R-HSA-109581
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of NMDA receptors and postsynaptic events R-HSA-442755
ESR-mediated signaling R-HSA-8939211
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Activin R-HSA-1502540
Cytokine Signaling in Immune system R-HSA-1280215
Oncogene Induced Senescence R-HSA-2559585
MAP kinase activation R-HSA-450294
Immune System R-HSA-168256
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MAPK3 (ERK1) activation R-HSA-110056
Neuronal System R-HSA-112316
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MAPK family signaling cascades R-HSA-5683057
Signaling by TGF-beta Receptor Complex R-HSA-170834
Negative regulation of MAPK pathway R-HSA-5675221
RUNX2 regulates bone development R-HSA-8941326
Interferon Signaling R-HSA-913531
RAF-independent MAPK1/3 activation R-HSA-112409
Generic Transcription Pathway R-HSA-212436
Signaling by FGFR R-HSA-190236
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Infection with Mycobacterium tuberculosis R-HSA-9635486
Negative regulation of FGFR1 signaling R-HSA-5654726
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Cellular responses to stimuli R-HSA-8953897
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular Senescence R-HSA-2559583
MyD88 cascade initiated on plasma membrane R-HSA-975871
Intracellular signaling by second messengers R-HSA-9006925
Signalling to ERKs R-HSA-187687
Signal attenuation R-HSA-74749
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Leishmania infection R-HSA-9658195
Regulation of the apoptosome activity R-HSA-9627069
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
MyD88 dependent cascade initiated on endosome R-HSA-975155
Hemostasis R-HSA-109582
Signaling by Nuclear Receptors R-HSA-9006931
Frs2-mediated activation R-HSA-170968
Post NMDA receptor activation events R-HSA-438064
Transmission across Chemical Synapses R-HSA-112315
Signaling by NODAL R-HSA-1181150
Suppression of apoptosis R-HSA-9635465
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by FGFR3 R-HSA-5654741
Infectious disease R-HSA-5663205
Signaling by ALK in cancer R-HSA-9700206
GPCR downstream signalling R-HSA-388396
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Transcriptional regulation by RUNX2 R-HSA-8878166
RSK activation R-HSA-444257
FCGR3A-mediated phagocytosis R-HSA-9664422
Oncogenic MAPK signaling R-HSA-6802957
Formation of apoptosome R-HSA-111458
Negative regulation of FGFR2 signaling R-HSA-5654727
Regulation of PTEN gene transcription R-HSA-8943724
Programmed Cell Death R-HSA-5357801
Signal transduction by L1 R-HSA-445144
Interleukin-17 signaling R-HSA-448424
Signaling by Rho GTPases R-HSA-194315
Cell Cycle, Mitotic R-HSA-69278
Insulin receptor signalling cascade R-HSA-74751
Negative regulation of the PI3K/AKT network R-HSA-199418
MAP2K and MAPK activation R-HSA-5674135
NPAS4 regulates expression of target genes R-HSA-9768919
Transcriptional Regulation by NPAS4 R-HSA-9634815
Activation of the AP-1 family of transcription factors R-HSA-450341
Disease R-HSA-1643685
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Negative regulation of FGFR3 signaling R-HSA-5654732
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by RAF1 mutants R-HSA-9656223
Intrinsic Pathway for Apoptosis R-HSA-109606
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Extra-nuclear estrogen signaling R-HSA-9009391
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Response of Mtb to phagocytosis R-HSA-9637690
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MAPK1/MAPK3 signaling R-HSA-5684996
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Mitotic Prophase R-HSA-68875
RHO GTPase Effectors R-HSA-195258
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by MAP2K mutants R-HSA-9652169
MyD88-independent TLR4 cascade R-HSA-166166
RAF/MAP kinase cascade R-HSA-5673001
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Oxidative Stress Induced Senescence R-HSA-2559580
Apoptotic factor-mediated response R-HSA-111471
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Axon guidance R-HSA-422475
L1CAM interactions R-HSA-373760
Leishmania phagocytosis R-HSA-9664417
Signal Transduction R-HSA-162582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Spry regulation of FGF signaling R-HSA-1295596
ERKs are inactivated R-HSA-202670
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by NTRKs R-HSA-166520
Growth hormone receptor signaling R-HSA-982772
Signaling by Insulin receptor R-HSA-74752
Parasite infection R-HSA-9664407
Signaling by RAS mutants R-HSA-6802949
Innate Immune System R-HSA-168249
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by FGFR2 R-HSA-5654738
Cytochrome c-mediated apoptotic response R-HSA-111461
RNA Polymerase I Promoter Opening R-HSA-73728
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by FGFR1 R-HSA-5654736
Nervous system development R-HSA-9675108
ISG15 antiviral mechanism R-HSA-1169408
Cell Cycle R-HSA-1640170
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Transcriptional Regulation by NPAS4 R-HSA-9634815
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
ESR-mediated signaling R-HSA-8939211
MAP2K and MAPK activation R-HSA-5674135
Developmental Biology R-HSA-1266738
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
RNA Polymerase I Promoter Opening R-HSA-73728
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Interleukin-17 signaling R-HSA-448424
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Neuronal System R-HSA-112316
RSK activation R-HSA-444257
MyD88-independent TLR4 cascade R-HSA-166166
Post NMDA receptor activation events R-HSA-438064
Signaling by Insulin receptor R-HSA-74752
RUNX2 regulates bone development R-HSA-8941326
Oxidative Stress Induced Senescence R-HSA-2559580
Activation of the AP-1 family of transcription factors R-HSA-450341
Activation of NMDA receptors and postsynaptic events R-HSA-442755
M Phase R-HSA-68886
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Activin R-HSA-1502540
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signal attenuation R-HSA-74749
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Interferon Signaling R-HSA-913531
Growth hormone receptor signaling R-HSA-982772
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by FGFR4 R-HSA-5654743
Signaling by RAF1 mutants R-HSA-9656223
Oncogenic MAPK signaling R-HSA-6802957
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Spry regulation of FGF signaling R-HSA-1295596
MAP kinase activation R-HSA-450294
Apoptotic factor-mediated response R-HSA-111471
RNA Polymerase II Transcription R-HSA-73857
Infection with Mycobacterium tuberculosis R-HSA-9635486
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
FCGR3A-mediated phagocytosis R-HSA-9664422
GPCR downstream signalling R-HSA-388396
Signaling by FGFR3 R-HSA-5654741
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Innate Immune System R-HSA-168249
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR1 R-HSA-5654736
ERK/MAPK targets R-HSA-198753
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Extra-nuclear estrogen signaling R-HSA-9009391
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RUNX2 regulates osteoblast differentiation R-HSA-8940973
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by NTRKs R-HSA-166520
Leishmania infection R-HSA-9658195
Programmed Cell Death R-HSA-5357801
Parasite infection R-HSA-9664407
MyD88 dependent cascade initiated on endosome R-HSA-975155
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by TGFB family members R-HSA-9006936
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NCAM signaling for neurite out-growth R-HSA-375165
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
L1CAM interactions R-HSA-373760
Signal Transduction R-HSA-162582
Frs2-mediated activation R-HSA-170968
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll-like Receptor Cascades R-HSA-168898
Negative regulation of MAPK pathway R-HSA-5675221
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
FCERI mediated MAPK activation R-HSA-2871796
Signaling by MAP2K mutants R-HSA-9652169
Signaling by ALK in cancer R-HSA-9700206
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Cellular Senescence R-HSA-2559583
Infectious disease R-HSA-5663205
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Generic Transcription Pathway R-HSA-212436
Intrinsic Pathway for Apoptosis R-HSA-109606
Mitotic Prophase R-HSA-68875
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by GPCR R-HSA-372790
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling downstream of RAS mutants R-HSA-9649948
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RNA Polymerase I Transcription R-HSA-73864
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by RAS mutants R-HSA-6802949
ERKs are inactivated R-HSA-202670
Cell Cycle, Mitotic R-HSA-69278
Regulation of PTEN gene transcription R-HSA-8943724
Negative regulation of FGFR3 signaling R-HSA-5654732
MAPK family signaling cascades R-HSA-5683057
Negative regulation of FGFR1 signaling R-HSA-5654726
RAF/MAP kinase cascade R-HSA-5673001
Formation of apoptosome R-HSA-111458
Signaling by Nuclear Receptors R-HSA-9006931
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by NTRK1 (TRKA) R-HSA-187037
Immune System R-HSA-168256
Signaling by TGF-beta Receptor Complex R-HSA-170834
PIP3 activates AKT signaling R-HSA-1257604
MAPK3 (ERK1) activation R-HSA-110056
RAF-independent MAPK1/3 activation R-HSA-112409
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
MAPK1/MAPK3 signaling R-HSA-5684996
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cytochrome c-mediated apoptotic response R-HSA-111461
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of the apoptosome activity R-HSA-9627069
Signal transduction by L1 R-HSA-445144
Hemostasis R-HSA-109582
Oncogene Induced Senescence R-HSA-2559585
RHO GTPase Effectors R-HSA-195258
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Suppression of apoptosis R-HSA-9635465
Signaling by FGFR R-HSA-190236
Apoptosis R-HSA-109581
G alpha (q) signalling events R-HSA-416476
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Nervous system development R-HSA-9675108
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
PTEN Regulation R-HSA-6807070
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by FGFR2 R-HSA-5654738
Prolonged ERK activation events R-HSA-169893
Negative regulation of FGFR4 signaling R-HSA-5654733
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular response to heat stress R-HSA-3371556
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by Rho GTPases R-HSA-194315
Signaling by NODAL R-HSA-1181150
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Transmission across Chemical Synapses R-HSA-112315
Leishmania phagocytosis R-HSA-9664417
Response of Mtb to phagocytosis R-HSA-9637690
Cellular responses to stimuli R-HSA-8953897
Signalling to ERKs R-HSA-187687
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
FCGR3A-mediated phagocytosis R-HSA-9664422
Prolonged ERK activation events R-HSA-169893
Programmed Cell Death R-HSA-5357801
Signaling by NTRKs R-HSA-166520
Negative regulation of FGFR2 signaling R-HSA-5654727
Neuronal System R-HSA-112316
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Activin R-HSA-1502540
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by FGFR4 R-HSA-5654743
Apoptotic factor-mediated response R-HSA-111471
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Oncogene Induced Senescence R-HSA-2559585
Response of Mtb to phagocytosis R-HSA-9637690
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
ERKs are inactivated R-HSA-202670
Apoptosis R-HSA-109581
RHO GTPase Effectors R-HSA-195258
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by ALK fusions and activated point mutants R-HSA-9725370
RNA Polymerase II Transcription R-HSA-73857
MyD88 dependent cascade initiated on endosome R-HSA-975155
Formation of apoptosome R-HSA-111458
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Extra-nuclear estrogen signaling R-HSA-9009391
RSK activation R-HSA-444257
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Toll-like Receptor Cascades R-HSA-168898
Cell Cycle R-HSA-1640170
Innate Immune System R-HSA-168249
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Axon guidance R-HSA-422475
Signaling by ALK in cancer R-HSA-9700206
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
L1CAM interactions R-HSA-373760
Infection with Mycobacterium tuberculosis R-HSA-9635486
RNA Polymerase I Promoter Opening R-HSA-73728
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Frs2-mediated activation R-HSA-170968
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Hemostasis R-HSA-109582
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR3 R-HSA-5654741
ESR-mediated signaling R-HSA-8939211
Signaling by FGFR R-HSA-190236
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
RNA Polymerase I Transcription R-HSA-73864
Signaling by RAF1 mutants R-HSA-9656223
MAPK family signaling cascades R-HSA-5683057
Cellular Senescence R-HSA-2559583
Platelet activation, signaling and aggregation R-HSA-76002
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by NODAL R-HSA-1181150
Signalling to ERKs R-HSA-187687
Nervous system development R-HSA-9675108
Negative regulation of MAPK pathway R-HSA-5675221
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cell Cycle, Mitotic R-HSA-69278
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G alpha (q) signalling events R-HSA-416476
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Signaling by FGFR1 R-HSA-5654736
Insulin receptor signalling cascade R-HSA-74751
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Spry regulation of FGF signaling R-HSA-1295596
Cellular responses to stress R-HSA-2262752
GPCR downstream signalling R-HSA-388396
Intracellular signaling by second messengers R-HSA-9006925
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
MAP2K and MAPK activation R-HSA-5674135
Signaling by FGFR2 R-HSA-5654738
RUNX2 regulates bone development R-HSA-8941326
Activation of the AP-1 family of transcription factors R-HSA-450341
Suppression of apoptosis R-HSA-9635465
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-17 signaling R-HSA-448424
Disease R-HSA-1643685
Leishmania infection R-HSA-9658195
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signal attenuation R-HSA-74749
Signaling by Nuclear Receptors R-HSA-9006931
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by RAS mutants R-HSA-6802949
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK3 (ERK1) activation R-HSA-110056
Signaling by Rho GTPases R-HSA-194315
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Regulation of the apoptosome activity R-HSA-9627069
Growth hormone receptor signaling R-HSA-982772
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by MAP2K mutants R-HSA-9652169
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
ERK/MAPK targets R-HSA-198753
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Leishmania phagocytosis R-HSA-9664417
Cellular responses to stimuli R-HSA-8953897
Signaling by Interleukins R-HSA-449147
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signal transduction by L1 R-HSA-445144
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by GPCR R-HSA-372790
Negative feedback regulation of MAPK pathway R-HSA-5674499
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Negative regulation of FGFR1 signaling R-HSA-5654726
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RNA Polymerase I Promoter Clearance R-HSA-73854
Parasite infection R-HSA-9664407
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by TGFB family members R-HSA-9006936
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated MAPK activation R-HSA-2871796
MAP kinase activation R-HSA-450294
Transcriptional Regulation by NPAS4 R-HSA-9634815
Negative regulation of the PI3K/AKT network R-HSA-199418
Interferon Signaling R-HSA-913531
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intrinsic Pathway for Apoptosis R-HSA-109606
Post NMDA receptor activation events R-HSA-438064
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Infectious disease R-HSA-5663205
Transmission across Chemical Synapses R-HSA-112315
Regulation of PTEN gene transcription R-HSA-8943724
Oncogenic MAPK signaling R-HSA-6802957
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Extra-nuclear estrogen signaling R-HSA-9009391
Interferon Signaling R-HSA-913531
Transmission across Chemical Synapses R-HSA-112315
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR1 R-HSA-5654736
Apoptotic factor-mediated response R-HSA-111471
Signal transduction by L1 R-HSA-445144
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Rho GTPases R-HSA-194315
Leishmania phagocytosis R-HSA-9664417
MAPK family signaling cascades R-HSA-5683057
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
RNA Polymerase I Promoter Opening R-HSA-73728
Signaling by NODAL R-HSA-1181150
Immune System R-HSA-168256
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Post NMDA receptor activation events R-HSA-438064
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Hemostasis R-HSA-109582
Suppression of apoptosis R-HSA-9635465
Activation of the AP-1 family of transcription factors R-HSA-450341
PTEN Regulation R-HSA-6807070
Programmed Cell Death R-HSA-5357801
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by NTRKs R-HSA-166520
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Oncogenic MAPK signaling R-HSA-6802957
RNA Polymerase I Transcription R-HSA-73864
Interleukin-17 signaling R-HSA-448424
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR4 R-HSA-5654743
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Negative regulation of the PI3K/AKT network R-HSA-199418
Platelet activation, signaling and aggregation R-HSA-76002
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Insulin receptor R-HSA-74752
FCERI mediated MAPK activation R-HSA-2871796
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Frs2-mediated activation R-HSA-170968
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling downstream of RAS mutants R-HSA-9649948
Developmental Biology R-HSA-1266738
Negative regulation of FGFR1 signaling R-HSA-5654726
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Nuclear Receptors R-HSA-9006931
Mitotic Prophase R-HSA-68875
Neuronal System R-HSA-112316
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Growth hormone receptor signaling R-HSA-982772
MAP kinase activation R-HSA-450294
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll-like Receptor Cascades R-HSA-168898
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
MAPK3 (ERK1) activation R-HSA-110056
Signaling by FGFR3 R-HSA-5654741
Signaling by FGFR2 R-HSA-5654738
Parasite infection R-HSA-9664407
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by ALK in cancer R-HSA-9700206
Signaling by TGFB family members R-HSA-9006936
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by RAS mutants R-HSA-6802949
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
RUNX2 regulates bone development R-HSA-8941326
L1CAM interactions R-HSA-373760
Gene expression (Transcription) R-HSA-74160
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Prolonged ERK activation events R-HSA-169893
ERK/MAPK targets R-HSA-198753
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Oncogene Induced Senescence R-HSA-2559585
Negative feedback regulation of MAPK pathway R-HSA-5674499
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular response to heat stress R-HSA-3371556
Transcriptional regulation by RUNX2 R-HSA-8878166
Response of Mtb to phagocytosis R-HSA-9637690
Intracellular signaling by second messengers R-HSA-9006925
RAF-independent MAPK1/3 activation R-HSA-112409
RSK activation R-HSA-444257
Signaling by MAP2K mutants R-HSA-9652169
Nervous system development R-HSA-9675108
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Negative regulation of FGFR2 signaling R-HSA-5654727
MyD88 cascade initiated on plasma membrane R-HSA-975871
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of FGFR4 signaling R-HSA-5654733
Oxidative Stress Induced Senescence R-HSA-2559580
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR R-HSA-190236
Signaling by GPCR R-HSA-372790
Signaling by TGF-beta Receptor Complex R-HSA-170834
GPCR downstream signalling R-HSA-388396
Negative regulation of MAPK pathway R-HSA-5675221
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
M Phase R-HSA-68886
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Apoptosis R-HSA-109581
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Leishmania infection R-HSA-9658195
Intrinsic Pathway for Apoptosis R-HSA-109606
MyD88-independent TLR4 cascade R-HSA-166166
MAP2K and MAPK activation R-HSA-5674135
ERKs are inactivated R-HSA-202670
ESR-mediated signaling R-HSA-8939211
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
NPAS4 regulates expression of target genes R-HSA-9768919
Cellular responses to stimuli R-HSA-8953897
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Cellular Senescence R-HSA-2559583
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signalling to ERKs R-HSA-187687
Spry regulation of FGF signaling R-HSA-1295596
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Innate Immune System R-HSA-168249
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Signaling by NTRK1 (TRKA) R-HSA-187037
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
PIP3 activates AKT signaling R-HSA-1257604
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Formation of apoptosome R-HSA-111458
Regulation of the apoptosome activity R-HSA-9627069
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
RHO GTPase Effectors R-HSA-195258
MAPK1/MAPK3 signaling R-HSA-5684996
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signal attenuation R-HSA-74749
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of PTEN gene transcription R-HSA-8943724
Infection with Mycobacterium tuberculosis R-HSA-9635486
G alpha (q) signalling events R-HSA-416476
Signaling by Activin R-HSA-1502540
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR4 R-HSA-5654743
RNA Polymerase I Promoter Clearance R-HSA-73854
Activation of the AP-1 family of transcription factors R-HSA-450341
Infection with Mycobacterium tuberculosis R-HSA-9635486
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
MyD88-independent TLR4 cascade R-HSA-166166
PIP3 activates AKT signaling R-HSA-1257604
Regulation of HSF1-mediated heat shock response R-HSA-3371453
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by MAP2K mutants R-HSA-9652169
RSK activation R-HSA-444257
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MAPK family signaling cascades R-HSA-5683057
Signaling by NTRKs R-HSA-166520
Signaling by FGFR3 R-HSA-5654741
Developmental Biology R-HSA-1266738
Oncogenic MAPK signaling R-HSA-6802957
Suppression of apoptosis R-HSA-9635465
ERK/MAPK targets R-HSA-198753
Spry regulation of FGF signaling R-HSA-1295596
Disease R-HSA-1643685
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cell Cycle, Mitotic R-HSA-69278
Signaling by NTRK1 (TRKA) R-HSA-187037
Programmed Cell Death R-HSA-5357801
Axon guidance R-HSA-422475
Signaling downstream of RAS mutants R-HSA-9649948
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Oncogene Induced Senescence R-HSA-2559585
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Extra-nuclear estrogen signaling R-HSA-9009391
Signal transduction by L1 R-HSA-445144
Toll-like Receptor Cascades R-HSA-168898
Cellular response to heat stress R-HSA-3371556
Regulation of PTEN gene transcription R-HSA-8943724
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Prolonged ERK activation events R-HSA-169893
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Transmission across Chemical Synapses R-HSA-112315
Parasite infection R-HSA-9664407
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Generic Transcription Pathway R-HSA-212436
Negative regulation of the PI3K/AKT network R-HSA-199418
Cellular responses to stress R-HSA-2262752
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Frs2-mediated activation R-HSA-170968
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Intrinsic Pathway for Apoptosis R-HSA-109606
Formation of apoptosome R-HSA-111458
ISG15 antiviral mechanism R-HSA-1169408
Negative regulation of FGFR1 signaling R-HSA-5654726
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Cytokine Signaling in Immune system R-HSA-1280215
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAP kinase activation R-HSA-450294
RNA Polymerase I Promoter Opening R-HSA-73728
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
NCAM signaling for neurite out-growth R-HSA-375165
Leishmania phagocytosis R-HSA-9664417
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Interferon Signaling R-HSA-913531
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR2 signaling R-HSA-5654727
RUNX2 regulates bone development R-HSA-8941326
Interleukin-17 signaling R-HSA-448424
Immune System R-HSA-168256
Signaling by Insulin receptor R-HSA-74752
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Insulin receptor signalling cascade R-HSA-74751
Signaling by NODAL R-HSA-1181150
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Negative regulation of MAPK pathway R-HSA-5675221
Signal Transduction R-HSA-162582
Regulation of the apoptosome activity R-HSA-9627069
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Post NMDA receptor activation events R-HSA-438064
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Apoptotic factor-mediated response R-HSA-111471
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signal attenuation R-HSA-74749
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Hemostasis R-HSA-109582
MAP2K and MAPK activation R-HSA-5674135
ERKs are inactivated R-HSA-202670
Growth hormone receptor signaling R-HSA-982772
L1CAM interactions R-HSA-373760
Signaling by Rho GTPases R-HSA-194315
ESR-mediated signaling R-HSA-8939211
FCERI mediated MAPK activation R-HSA-2871796
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Response of Mtb to phagocytosis R-HSA-9637690
Neuronal System R-HSA-112316
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Cell Cycle R-HSA-1640170
RHO GTPase Effectors R-HSA-195258
Signaling by Nuclear Receptors R-HSA-9006931
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Oxidative Stress Induced Senescence R-HSA-2559580
Apoptosis R-HSA-109581
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signalling to ERKs R-HSA-187687
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
GPCR downstream signalling R-HSA-388396
RNA Polymerase I Transcription R-HSA-73864
Signaling by FGFR2 R-HSA-5654738
PTEN Regulation R-HSA-6807070
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by RAS mutants R-HSA-6802949
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by FGFR R-HSA-190236
Cytochrome c-mediated apoptotic response R-HSA-111461
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by ALK in cancer R-HSA-9700206
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by RAF1 mutants R-HSA-9656223
Cellular Senescence R-HSA-2559583
Transcriptional Regulation by NPAS4 R-HSA-9634815
Negative feedback regulation of MAPK pathway R-HSA-5674499
Cellular responses to stimuli R-HSA-8953897
Signaling by FGFR1 R-HSA-5654736
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by TGFB family members R-HSA-9006936
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Gene expression (Transcription) R-HSA-74160
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Leishmania infection R-HSA-9658195
Signaling by GPCR R-HSA-372790
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Activin R-HSA-1502540
MyD88 cascade initiated on plasma membrane R-HSA-975871
Negative regulation of FGFR3 signaling R-HSA-5654732
MAPK3 (ERK1) activation R-HSA-110056

Expression Atlas ENSG00000102882
NCBI gene (formerly Entrezgene) 5595
GeneCards 6877
HGNC Symbol HGNC:6877
MIM gene 601795
UniProtKB Gene Name P27361
WikiGene 5595
Gene: GSK3B
Ensembl ID : ENSG00000082701
Description: glycogen synthase kinase 3 beta
Gene Synonyms:
6 APIs:
244 Possible Orthologues:

GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743
Late SARS-CoV-2 Infection Events R-HSA-9772573
Gene expression (Transcription) R-HSA-74160
Cellular response to chemical stress R-HSA-9711123
CRMPs in Sema3A signaling R-HSA-399956
AKT phosphorylates targets in the cytosol R-HSA-198323
Cellular responses to stress R-HSA-2262752
Epigenetic regulation of gene expression R-HSA-212165
SARS-CoV-2 Infection R-HSA-9694516
Degradation of beta-catenin by the destruction complex R-HSA-195253
KEAP1-NFE2L2 pathway R-HSA-9755511
Infectious disease R-HSA-5663205
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
Signaling by APC mutants R-HSA-4839744
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Cellular response to heat stress R-HSA-3371556
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
Maturation of nucleoprotein R-HSA-9694631
SARS-CoV Infections R-HSA-9679506
Signaling by GSK3beta mutants R-HSA-5339716
Hedgehog 'off' state R-HSA-5610787
Signaling by AXIN mutants R-HSA-4839735
Signaling by WNT in cancer R-HSA-4791275
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751
RNA Polymerase II Transcription R-HSA-73857
Regulation of RUNX2 expression and activity R-HSA-8939902
Translation of Structural Proteins R-HSA-9683701
SARS-CoV-1 Infection R-HSA-9678108
APC truncation mutants have impaired AXIN binding R-HSA-5467337
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
B-WICH complex positively regulates rRNA expression R-HSA-5250924
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747
Nuclear events mediated by NFE2L2 R-HSA-9759194
Nervous system development R-HSA-9675108
Beta-catenin phosphorylation cascade R-HSA-196299
Positive epigenetic regulation of rRNA expression R-HSA-5250913
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Hedgehog R-HSA-5358351
Translation of Structural Proteins R-HSA-9694635
Semaphorin interactions R-HSA-373755
Signaling by WNT R-HSA-195721
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749
PIP3 activates AKT signaling R-HSA-1257604
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262
AXIN missense mutants destabilize the destruction complex R-HSA-5467340
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle R-HSA-1640170
Maturation of nucleoprotein R-HSA-9683610
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
Cell Cycle, Mitotic R-HSA-69278
Signaling by AMER1 mutants R-HSA-4839748
PI3K/AKT Signaling in Cancer R-HSA-2219528
Transcriptional regulation by RUNX2 R-HSA-8878166
S Phase R-HSA-69242
AXIN missense mutants destabilize the destruction complex R-HSA-5467340
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
TCF dependent signaling in response to WNT R-HSA-201681
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747
Signaling by AXIN mutants R-HSA-4839735
SARS-CoV-1 Infection R-HSA-9678108
Axon guidance R-HSA-422475
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751
Beta-catenin phosphorylation cascade R-HSA-196299
AKT phosphorylates targets in the cytosol R-HSA-198323
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Translation of Structural Proteins R-HSA-9683701
RNA Polymerase II Transcription R-HSA-73857
Maturation of nucleoprotein R-HSA-9683610
Cellular responses to stress R-HSA-2262752
SARS-CoV Infections R-HSA-9679506
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events mediated by NFE2L2 R-HSA-9759194
B-WICH complex positively regulates rRNA expression R-HSA-5250924
Infectious disease R-HSA-5663205
Cellular responses to stimuli R-HSA-8953897
Signaling by Hedgehog R-HSA-5358351
Positive epigenetic regulation of rRNA expression R-HSA-5250913
Signaling by WNT R-HSA-195721
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of HSF1-mediated heat shock response R-HSA-3371453
SARS-CoV-2 Infection R-HSA-9694516
Degradation of GLI2 by the proteasome R-HSA-5610783
Cellular response to chemical stress R-HSA-9711123
S Phase R-HSA-69242
Transcriptional regulation by RUNX2 R-HSA-8878166
Late SARS-CoV-2 Infection Events R-HSA-9772573
Regulation of RUNX2 expression and activity R-HSA-8939902
Disease R-HSA-1643685
CRMPs in Sema3A signaling R-HSA-399956
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262
Cellular response to heat stress R-HSA-3371556
Generic Transcription Pathway R-HSA-212436
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743
Signal Transduction R-HSA-162582
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752
Semaphorin interactions R-HSA-373755
APC truncation mutants have impaired AXIN binding R-HSA-5467337
Gene expression (Transcription) R-HSA-74160
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by APC mutants R-HSA-4839744
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
Signaling by AMER1 mutants R-HSA-4839748
Signaling by WNT in cancer R-HSA-4791275
Cell Cycle R-HSA-1640170
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749
Signaling by GSK3beta mutants R-HSA-5339716
Epigenetic regulation of gene expression R-HSA-212165
Hedgehog 'off' state R-HSA-5610787
Maturation of nucleoprotein R-HSA-9694631
Translation of Structural Proteins R-HSA-9694635
PI3K/AKT Signaling in Cancer R-HSA-2219528
Nervous system development R-HSA-9675108
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV Infections R-HSA-9679506
Cell Cycle R-HSA-1640170
Cellular response to heat stress R-HSA-3371556
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by GSK3beta mutants R-HSA-5339716
AXIN missense mutants destabilize the destruction complex R-HSA-5467340
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of HSF1-mediated heat shock response R-HSA-3371453
PIP3 activates AKT signaling R-HSA-1257604
APC truncation mutants have impaired AXIN binding R-HSA-5467337
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Semaphorin interactions R-HSA-373755
CRMPs in Sema3A signaling R-HSA-399956
S Phase R-HSA-69242
Translation of Structural Proteins R-HSA-9694635
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348
B-WICH complex positively regulates rRNA expression R-HSA-5250924
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'off' state R-HSA-5610787
Intracellular signaling by second messengers R-HSA-9006925
Beta-catenin phosphorylation cascade R-HSA-196299
AKT phosphorylates targets in the cytosol R-HSA-198323
Maturation of nucleoprotein R-HSA-9694631
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747
Gene expression (Transcription) R-HSA-74160
Epigenetic regulation of gene expression R-HSA-212165
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX2 R-HSA-8878166
Maturation of nucleoprotein R-HSA-9683610
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by AMER1 mutants R-HSA-4839748
Nuclear events mediated by NFE2L2 R-HSA-9759194
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cell Cycle, Mitotic R-HSA-69278
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743
Signaling by WNT in cancer R-HSA-4791275
Signaling by AXIN mutants R-HSA-4839735
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752
Signaling by WNT R-HSA-195721
Late SARS-CoV-2 Infection Events R-HSA-9772573
Disease R-HSA-1643685
Translation of Structural Proteins R-HSA-9683701
SARS-CoV-1 Infection R-HSA-9678108
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Infectious disease R-HSA-5663205
PI3K/AKT Signaling in Cancer R-HSA-2219528
SARS-CoV-2 Infection R-HSA-9694516
Signaling by APC mutants R-HSA-4839744
Degradation of GLI2 by the proteasome R-HSA-5610783
Positive epigenetic regulation of rRNA expression R-HSA-5250913
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Hedgehog R-HSA-5358351
Signal Transduction R-HSA-162582
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743
Signaling by Hedgehog R-HSA-5358351
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by WNT R-HSA-195721
Axon guidance R-HSA-422475
Signaling by WNT in cancer R-HSA-4791275
SARS-CoV Infections R-HSA-9679506
Signaling by GSK3beta mutants R-HSA-5339716
Developmental Biology R-HSA-1266738
Cellular response to chemical stress R-HSA-9711123
Positive epigenetic regulation of rRNA expression R-HSA-5250913
Degradation of beta-catenin by the destruction complex R-HSA-195253
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747
RNA Polymerase II Transcription R-HSA-73857
S Phase R-HSA-69242
SARS-CoV-2 Infection R-HSA-9694516
Late SARS-CoV-2 Infection Events R-HSA-9772573
Transcriptional regulation by RUNX2 R-HSA-8878166
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749
Cellular responses to stress R-HSA-2262752
Beta-catenin phosphorylation cascade R-HSA-196299
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348
Signaling by AXIN mutants R-HSA-4839735
Nervous system development R-HSA-9675108
Translation of Structural Proteins R-HSA-9694635
Disease R-HSA-1643685
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Maturation of nucleoprotein R-HSA-9683610
Cellular responses to stimuli R-HSA-8953897
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752
B-WICH complex positively regulates rRNA expression R-HSA-5250924
Degradation of GLI2 by the proteasome R-HSA-5610783
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog 'off' state R-HSA-5610787
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV-1 Infection R-HSA-9678108
Intracellular signaling by second messengers R-HSA-9006925
Signaling by AMER1 mutants R-HSA-4839748
Generic Transcription Pathway R-HSA-212436
Regulation of RUNX2 expression and activity R-HSA-8939902
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Semaphorin interactions R-HSA-373755
CRMPs in Sema3A signaling R-HSA-399956
Signaling by APC mutants R-HSA-4839744
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Maturation of nucleoprotein R-HSA-9694631
PIP3 activates AKT signaling R-HSA-1257604
Epigenetic regulation of gene expression R-HSA-212165
Cell Cycle R-HSA-1640170
Nuclear events mediated by NFE2L2 R-HSA-9759194
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751
AKT phosphorylates targets in the cytosol R-HSA-198323
TCF dependent signaling in response to WNT R-HSA-201681
Translation of Structural Proteins R-HSA-9683701
Cellular response to heat stress R-HSA-3371556
APC truncation mutants have impaired AXIN binding R-HSA-5467337
Infectious disease R-HSA-5663205
AXIN missense mutants destabilize the destruction complex R-HSA-5467340
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747
Transcriptional regulation by RUNX2 R-HSA-8878166
AXIN missense mutants destabilize the destruction complex R-HSA-5467340
Beta-catenin phosphorylation cascade R-HSA-196299
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by APC mutants R-HSA-4839744
Cell Cycle, Mitotic R-HSA-69278
Epigenetic regulation of gene expression R-HSA-212165
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751
Cell Cycle R-HSA-1640170
Hedgehog 'off' state R-HSA-5610787
Cellular response to chemical stress R-HSA-9711123
APC truncation mutants have impaired AXIN binding R-HSA-5467337
Nervous system development R-HSA-9675108
Cellular responses to stimuli R-HSA-8953897
Signaling by AXIN mutants R-HSA-4839735
SARS-CoV-1 Infection R-HSA-9678108
Degradation of GLI2 by the proteasome R-HSA-5610783
Disease R-HSA-1643685
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752
Semaphorin interactions R-HSA-373755
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signal Transduction R-HSA-162582
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by AMER1 mutants R-HSA-4839748
Signaling by WNT in cancer R-HSA-4791275
Cellular response to heat stress R-HSA-3371556
SARS-CoV-2 Infection R-HSA-9694516
Translation of Structural Proteins R-HSA-9694635
Intracellular signaling by second messengers R-HSA-9006925
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
B-WICH complex positively regulates rRNA expression R-HSA-5250924
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Maturation of nucleoprotein R-HSA-9694631
RNA Polymerase II Transcription R-HSA-73857
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Axon guidance R-HSA-422475
Signaling by WNT R-HSA-195721
Signaling by GSK3beta mutants R-HSA-5339716
Maturation of nucleoprotein R-HSA-9683610
Infectious disease R-HSA-5663205
Translation of Structural Proteins R-HSA-9683701
PI3K/AKT Signaling in Cancer R-HSA-2219528
Developmental Biology R-HSA-1266738
Positive epigenetic regulation of rRNA expression R-HSA-5250913
Late SARS-CoV-2 Infection Events R-HSA-9772573
Nuclear events mediated by NFE2L2 R-HSA-9759194
SARS-CoV Infections R-HSA-9679506
Cellular responses to stress R-HSA-2262752
CRMPs in Sema3A signaling R-HSA-399956
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262
AKT phosphorylates targets in the cytosol R-HSA-198323
Signaling by Hedgehog R-HSA-5358351
Late SARS-CoV-2 Infection Events R-HSA-9772573
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Disease R-HSA-1643685
Translation of Structural Proteins R-HSA-9694635
Degradation of GLI2 by the proteasome R-HSA-5610783
PI3K/AKT Signaling in Cancer R-HSA-2219528
Developmental Biology R-HSA-1266738
Cellular response to heat stress R-HSA-3371556
SARS-CoV-2 Infection R-HSA-9694516
Semaphorin interactions R-HSA-373755
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262
Translation of Structural Proteins R-HSA-9683701
Signaling by Hedgehog R-HSA-5358351
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749
Signaling by WNT R-HSA-195721
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV Infections R-HSA-9679506
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747
PIP3 activates AKT signaling R-HSA-1257604
CRMPs in Sema3A signaling R-HSA-399956
Cell Cycle R-HSA-1640170
AKT phosphorylates targets in the cytosol R-HSA-198323
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by APC mutants R-HSA-4839744
Signal Transduction R-HSA-162582
Signaling by WNT in cancer R-HSA-4791275
Signaling by AMER1 mutants R-HSA-4839748
B-WICH complex positively regulates rRNA expression R-HSA-5250924
Cellular responses to stimuli R-HSA-8953897
Maturation of nucleoprotein R-HSA-9694631
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743
Cell Cycle, Mitotic R-HSA-69278
APC truncation mutants have impaired AXIN binding R-HSA-5467337
Cellular response to chemical stress R-HSA-9711123
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by GSK3beta mutants R-HSA-5339716
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
Beta-catenin phosphorylation cascade R-HSA-196299
Hedgehog 'off' state R-HSA-5610787
Regulation of RUNX2 expression and activity R-HSA-8939902
Axon guidance R-HSA-422475
Signaling by AXIN mutants R-HSA-4839735
Cellular responses to stress R-HSA-2262752
Positive epigenetic regulation of rRNA expression R-HSA-5250913
Maturation of nucleoprotein R-HSA-9683610
Epigenetic regulation of gene expression R-HSA-212165
Gene expression (Transcription) R-HSA-74160
Intracellular signaling by second messengers R-HSA-9006925
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348
Generic Transcription Pathway R-HSA-212436
AXIN missense mutants destabilize the destruction complex R-HSA-5467340
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by AXIN mutants R-HSA-4839735
Maturation of nucleoprotein R-HSA-9683610
Nuclear events mediated by NFE2L2 R-HSA-9759194
Positive epigenetic regulation of rRNA expression R-HSA-5250913
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by AMER1 mutants R-HSA-4839748
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749
Signal Transduction R-HSA-162582
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
Cell Cycle, Mitotic R-HSA-69278
Signaling by GSK3beta mutants R-HSA-5339716
Translation of Structural Proteins R-HSA-9683701
Epigenetic regulation of gene expression R-HSA-212165
Degradation of beta-catenin by the destruction complex R-HSA-195253
TCF dependent signaling in response to WNT R-HSA-201681
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747
AXIN missense mutants destabilize the destruction complex R-HSA-5467340
Translation of Structural Proteins R-HSA-9694635
Late SARS-CoV-2 Infection Events R-HSA-9772573
SARS-CoV-1 Infection R-HSA-9678108
Intracellular signaling by second messengers R-HSA-9006925
Beta-catenin phosphorylation cascade R-HSA-196299
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle R-HSA-1640170
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
Signaling by WNT in cancer R-HSA-4791275
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262
Maturation of nucleoprotein R-HSA-9694631
CRMPs in Sema3A signaling R-HSA-399956
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752
APC truncation mutants have impaired AXIN binding R-HSA-5467337
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751
Gene expression (Transcription) R-HSA-74160
B-WICH complex positively regulates rRNA expression R-HSA-5250924
Nervous system development R-HSA-9675108
Cellular response to heat stress R-HSA-3371556
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular responses to stress R-HSA-2262752
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743
AKT phosphorylates targets in the cytosol R-HSA-198323
Hedgehog 'off' state R-HSA-5610787
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348
Infectious disease R-HSA-5663205
Cellular response to chemical stress R-HSA-9711123
Signaling by APC mutants R-HSA-4839744
Disease R-HSA-1643685
Semaphorin interactions R-HSA-373755
SARS-CoV Infections R-HSA-9679506
SARS-CoV-2 Infection R-HSA-9694516
Signaling by WNT R-HSA-195721
Signaling by Hedgehog R-HSA-5358351
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Axon guidance R-HSA-422475
B-WICH complex positively regulates rRNA expression R-HSA-5250924
AKT phosphorylates targets in the cytosol R-HSA-198323
Beta-catenin phosphorylation cascade R-HSA-196299
Late SARS-CoV-2 Infection Events R-HSA-9772573
AXIN missense mutants destabilize the destruction complex R-HSA-5467340
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747
APC truncation mutants have impaired AXIN binding R-HSA-5467337
Translation of Structural Proteins R-HSA-9694635
Signaling by APC mutants R-HSA-4839744
Transcriptional regulation by RUNX2 R-HSA-8878166
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Signaling by GSK3beta mutants R-HSA-5339716
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by AMER1 mutants R-HSA-4839748
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
Signaling by AXIN mutants R-HSA-4839735
RNA Polymerase II Transcription R-HSA-73857
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of HSF1-mediated heat shock response R-HSA-3371453
S Phase R-HSA-69242
Cellular response to heat stress R-HSA-3371556
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Gene expression (Transcription) R-HSA-74160
CRMPs in Sema3A signaling R-HSA-399956
Nervous system development R-HSA-9675108
Cell Cycle R-HSA-1640170
Axon guidance R-HSA-422475
SARS-CoV-2 Infection R-HSA-9694516
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog 'off' state R-HSA-5610787
Cellular response to chemical stress R-HSA-9711123
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743
SARS-CoV Infections R-HSA-9679506
Epigenetic regulation of gene expression R-HSA-212165
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
Translation of Structural Proteins R-HSA-9683701
Degradation of GLI2 by the proteasome R-HSA-5610783
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749
Signaling by Hedgehog R-HSA-5358351
SARS-CoV-1 Infection R-HSA-9678108
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348
Maturation of nucleoprotein R-HSA-9683610
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751
Cellular responses to stimuli R-HSA-8953897
TCF dependent signaling in response to WNT R-HSA-201681
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262
Signaling by WNT in cancer R-HSA-4791275
Maturation of nucleoprotein R-HSA-9694631
Semaphorin interactions R-HSA-373755
Cellular responses to stress R-HSA-2262752
Cell Cycle, Mitotic R-HSA-69278
Signaling by WNT R-HSA-195721
Positive epigenetic regulation of rRNA expression R-HSA-5250913
Generic Transcription Pathway R-HSA-212436
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signal Transduction R-HSA-162582
KEAP1-NFE2L2 pathway R-HSA-9755511
Intracellular signaling by second messengers R-HSA-9006925
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348
Positive epigenetic regulation of rRNA expression R-HSA-5250913
CRMPs in Sema3A signaling R-HSA-399956
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749
Signaling by Hedgehog R-HSA-5358351
Translation of Structural Proteins R-HSA-9683701
AXIN missense mutants destabilize the destruction complex R-HSA-5467340
SARS-CoV-2 Infection R-HSA-9694516
Signaling by WNT in cancer R-HSA-4791275
Beta-catenin phosphorylation cascade R-HSA-196299
Axon guidance R-HSA-422475
S Phase R-HSA-69242
B-WICH complex positively regulates rRNA expression R-HSA-5250924
Maturation of nucleoprotein R-HSA-9683610
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
TCF dependent signaling in response to WNT R-HSA-201681
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747
Cellular responses to stress R-HSA-2262752
KEAP1-NFE2L2 pathway R-HSA-9755511
Semaphorin interactions R-HSA-373755
Generic Transcription Pathway R-HSA-212436
Late SARS-CoV-2 Infection Events R-HSA-9772573
PI3K/AKT Signaling in Cancer R-HSA-2219528
Maturation of nucleoprotein R-HSA-9694631
Regulation of RUNX2 expression and activity R-HSA-8939902
SARS-CoV Infections R-HSA-9679506
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Cell Cycle, Mitotic R-HSA-69278
Signaling by GSK3beta mutants R-HSA-5339716
SARS-CoV-1 Infection R-HSA-9678108
Translation of Structural Proteins R-HSA-9694635
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Signaling by APC mutants R-HSA-4839744
Cell Cycle R-HSA-1640170
PIP3 activates AKT signaling R-HSA-1257604
Epigenetic regulation of gene expression R-HSA-212165
Gene expression (Transcription) R-HSA-74160
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular response to heat stress R-HSA-3371556
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262
Signaling by AXIN mutants R-HSA-4839735
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Nuclear events mediated by NFE2L2 R-HSA-9759194
AKT phosphorylates targets in the cytosol R-HSA-198323
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular response to chemical stress R-HSA-9711123
APC truncation mutants have impaired AXIN binding R-HSA-5467337
Hedgehog 'off' state R-HSA-5610787
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743
RNA Polymerase II Transcription R-HSA-73857
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Infectious disease R-HSA-5663205
Signaling by AMER1 mutants R-HSA-4839748
B-WICH complex positively regulates rRNA expression R-HSA-5250924
Maturation of nucleoprotein R-HSA-9683610
Beta-catenin phosphorylation cascade R-HSA-196299
Degradation of GLI2 by the proteasome R-HSA-5610783
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
SARS-CoV-1 Infection R-HSA-9678108
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Signaling by AXIN mutants R-HSA-4839735
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by Hedgehog R-HSA-5358351
Signal Transduction R-HSA-162582
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348
Late SARS-CoV-2 Infection Events R-HSA-9772573
Translation of Structural Proteins R-HSA-9694635
Axon guidance R-HSA-422475
Semaphorin interactions R-HSA-373755
Intracellular signaling by second messengers R-HSA-9006925
S Phase R-HSA-69242
Maturation of nucleoprotein R-HSA-9694631
Developmental Biology R-HSA-1266738
APC truncation mutants have impaired AXIN binding R-HSA-5467337
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog 'off' state R-HSA-5610787
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749
Cell Cycle R-HSA-1640170
Positive epigenetic regulation of rRNA expression R-HSA-5250913
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262
PI3K/AKT Signaling in Cancer R-HSA-2219528
SARS-CoV Infections R-HSA-9679506
TCF dependent signaling in response to WNT R-HSA-201681
Translation of Structural Proteins R-HSA-9683701
Signaling by AMER1 mutants R-HSA-4839748
Cellular response to heat stress R-HSA-3371556
Generic Transcription Pathway R-HSA-212436
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Disease R-HSA-1643685
SARS-CoV-2 Infection R-HSA-9694516
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747
PIP3 activates AKT signaling R-HSA-1257604
AKT phosphorylates targets in the cytosol R-HSA-198323
CRMPs in Sema3A signaling R-HSA-399956
Cell Cycle, Mitotic R-HSA-69278
Degradation of beta-catenin by the destruction complex R-HSA-195253
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751
Cellular responses to stress R-HSA-2262752
Signaling by WNT in cancer R-HSA-4791275
Signaling by GSK3beta mutants R-HSA-5339716
Cellular response to chemical stress R-HSA-9711123
Signaling by WNT R-HSA-195721
Signaling by APC mutants R-HSA-4839744
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Epigenetic regulation of gene expression R-HSA-212165
AXIN missense mutants destabilize the destruction complex R-HSA-5467340
KEAP1-NFE2L2 pathway R-HSA-9755511
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Signaling by GSK3beta mutants R-HSA-5339716
Signaling by APC mutants R-HSA-4839744
Cell Cycle, Mitotic R-HSA-69278
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747
Degradation of beta-catenin by the destruction complex R-HSA-195253
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752
APC truncation mutants have impaired AXIN binding R-HSA-5467337
Maturation of nucleoprotein R-HSA-9694631
Degradation of GLI2 by the proteasome R-HSA-5610783
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262
SARS-CoV-1 Infection R-HSA-9678108
Developmental Biology R-HSA-1266738
AXIN missense mutants destabilize the destruction complex R-HSA-5467340
PIP3 activates AKT signaling R-HSA-1257604
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Maturation of nucleoprotein R-HSA-9683610
Intracellular signaling by second messengers R-HSA-9006925
TCF dependent signaling in response to WNT R-HSA-201681
Transcriptional regulation by RUNX2 R-HSA-8878166
Infectious disease R-HSA-5663205
Translation of Structural Proteins R-HSA-9683701
RNA Polymerase II Transcription R-HSA-73857
Translation of Structural Proteins R-HSA-9694635
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Gene expression (Transcription) R-HSA-74160
Late SARS-CoV-2 Infection Events R-HSA-9772573
Signaling by AMER1 mutants R-HSA-4839748
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Hedgehog R-HSA-5358351
Semaphorin interactions R-HSA-373755
Signaling by AXIN mutants R-HSA-4839735
AKT phosphorylates targets in the cytosol R-HSA-198323
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743
SARS-CoV Infections R-HSA-9679506
Cellular response to heat stress R-HSA-3371556
Cell Cycle R-HSA-1640170
Cellular responses to stress R-HSA-2262752
Signaling by WNT R-HSA-195721
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Nuclear events mediated by NFE2L2 R-HSA-9759194
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749
Hedgehog 'off' state R-HSA-5610787
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348
Epigenetic regulation of gene expression R-HSA-212165
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Cellular response to chemical stress R-HSA-9711123
Beta-catenin phosphorylation cascade R-HSA-196299
Regulation of RUNX2 expression and activity R-HSA-8939902
SARS-CoV-2 Infection R-HSA-9694516
B-WICH complex positively regulates rRNA expression R-HSA-5250924
S Phase R-HSA-69242
Signaling by WNT in cancer R-HSA-4791275
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Axon guidance R-HSA-422475
CRMPs in Sema3A signaling R-HSA-399956
Cellular responses to stimuli R-HSA-8953897
Positive epigenetic regulation of rRNA expression R-HSA-5250913

Expression Atlas ENSG00000082701
NCBI gene (formerly Entrezgene) 2932
GeneCards 4617
HGNC Symbol HGNC:4617
MIM gene 605004
UniProtKB Gene Name Q6FI27
WikiGene 2932
Gene: MAPK8
Ensembl ID : ENSG00000107643
Description: mitogen-activated protein kinase 8
Gene Synonyms: JNK,JNK1,PRKM8,SAPK1
3 APIs:
292 Possible Orthologues:

Cellular responses to stress R-HSA-2262752
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
DSCAM interactions R-HSA-376172
Disease R-HSA-1643685
Innate Immune System R-HSA-168249
DNA Double-Strand Break Repair R-HSA-5693532
Infectious disease R-HSA-5663205
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular responses to stimuli R-HSA-8953897
Activation of BMF and translocation to mitochondria R-HSA-139910
Activation of BIM and translocation to mitochondria R-HSA-111446
Killing mechanisms R-HSA-9664420
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
NRAGE signals death through JNK R-HSA-193648
Nervous system development R-HSA-9675108
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Axon guidance R-HSA-422475
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Programmed Cell Death R-HSA-5357801
Toll-like Receptor Cascades R-HSA-168898
Cytokine Signaling in Immune system R-HSA-1280215
DNA Double Strand Break Response R-HSA-5693606
Interleukin-1 family signaling R-HSA-446652
Netrin-1 signaling R-HSA-373752
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Activation of the AP-1 family of transcription factors R-HSA-450341
Developmental Biology R-HSA-1266738
Intrinsic Pathway for Apoptosis R-HSA-109606
DNA Repair R-HSA-73894
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88 cascade initiated on plasma membrane R-HSA-975871
Immune System R-HSA-168256
Leishmania infection R-HSA-9658195
Apoptosis R-HSA-109581
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular Senescence R-HSA-2559583
MyD88 dependent cascade initiated on endosome R-HSA-975155
MAP kinase activation R-HSA-450294
FCERI mediated MAPK activation R-HSA-2871796
Activation of BH3-only proteins R-HSA-114452
p75 NTR receptor-mediated signalling R-HSA-193704
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Interleukin-38 signaling R-HSA-9007892
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Death Receptor Signaling R-HSA-73887
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
NRIF signals cell death from the nucleus R-HSA-205043
Signal Transduction R-HSA-162582
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583
Activation of BH3-only proteins R-HSA-114452
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by Interleukins R-HSA-449147
Nervous system development R-HSA-9675108
NRIF signals cell death from the nucleus R-HSA-205043
FCERI mediated MAPK activation R-HSA-2871796
DNA Repair R-HSA-73894
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Infectious disease R-HSA-5663205
DNA Double-Strand Break Repair R-HSA-5693532
Netrin-1 signaling R-HSA-373752
Activation of BIM and translocation to mitochondria R-HSA-111446
Immune System R-HSA-168256
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
NRAGE signals death through JNK R-HSA-193648
Cellular responses to stress R-HSA-2262752
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Programmed Cell Death R-HSA-5357801
Death Receptor Signaling R-HSA-73887
Leishmania infection R-HSA-9658195
Interleukin-1 family signaling R-HSA-446652
Interleukin-38 signaling R-HSA-9007892
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Intrinsic Pathway for Apoptosis R-HSA-109606
MyD88 cascade initiated on plasma membrane R-HSA-975871
MAP kinase activation R-HSA-450294
Killing mechanisms R-HSA-9664420
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Developmental Biology R-HSA-1266738
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Activation of BMF and translocation to mitochondria R-HSA-139910
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Activation of the AP-1 family of transcription factors R-HSA-450341
Innate Immune System R-HSA-168249
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
p75 NTR receptor-mediated signalling R-HSA-193704
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Axon guidance R-HSA-422475
Apoptosis R-HSA-109581
MyD88 dependent cascade initiated on endosome R-HSA-975155
DSCAM interactions R-HSA-376172
DNA Double Strand Break Response R-HSA-5693606
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll-like Receptor Cascades R-HSA-168898
Cellular responses to stimuli R-HSA-8953897
Innate Immune System R-HSA-168249
MyD88 cascade initiated on plasma membrane R-HSA-975871
DSCAM interactions R-HSA-376172
Infectious disease R-HSA-5663205
NRAGE signals death through JNK R-HSA-193648
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
NRIF signals cell death from the nucleus R-HSA-205043
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cytokine Signaling in Immune system R-HSA-1280215
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Interleukins R-HSA-449147
DNA Double Strand Break Response R-HSA-5693606
MyD88-independent TLR4 cascade R-HSA-166166
Cellular responses to stress R-HSA-2262752
DNA Repair R-HSA-73894
Netrin-1 signaling R-HSA-373752
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Cellular responses to stimuli R-HSA-8953897
Disease R-HSA-1643685
Activation of the AP-1 family of transcription factors R-HSA-450341
Cellular Senescence R-HSA-2559583
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Intrinsic Pathway for Apoptosis R-HSA-109606
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Activation of BMF and translocation to mitochondria R-HSA-139910
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
DNA Double-Strand Break Repair R-HSA-5693532
Activation of BIM and translocation to mitochondria R-HSA-111446
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
Interleukin-1 family signaling R-HSA-446652
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
FCERI mediated MAPK activation R-HSA-2871796
Apoptosis R-HSA-109581
Nervous system development R-HSA-9675108
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Activation of BH3-only proteins R-HSA-114452
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Leishmania infection R-HSA-9658195
Immune System R-HSA-168256
Interleukin-38 signaling R-HSA-9007892
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Death Receptor Signaling R-HSA-73887
Programmed Cell Death R-HSA-5357801
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MAP kinase activation R-HSA-450294
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Developmental Biology R-HSA-1266738
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Killing mechanisms R-HSA-9664420
Killing mechanisms R-HSA-9664420
Activation of BIM and translocation to mitochondria R-HSA-111446
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Disease R-HSA-1643685
MyD88 dependent cascade initiated on endosome R-HSA-975155
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
DNA Double-Strand Break Repair R-HSA-5693532
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll-like Receptor Cascades R-HSA-168898
Netrin-1 signaling R-HSA-373752
MAP kinase activation R-HSA-450294
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Cellular Senescence R-HSA-2559583
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Oxidative Stress Induced Senescence R-HSA-2559580
Infectious disease R-HSA-5663205
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Activation of BMF and translocation to mitochondria R-HSA-139910
NRAGE signals death through JNK R-HSA-193648
Cellular responses to stress R-HSA-2262752
Intrinsic Pathway for Apoptosis R-HSA-109606
Apoptosis R-HSA-109581
Interleukin-38 signaling R-HSA-9007892
DNA Double Strand Break Response R-HSA-5693606
Leishmania infection R-HSA-9658195
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Activation of BH3-only proteins R-HSA-114452
DSCAM interactions R-HSA-376172
Interleukin-17 signaling R-HSA-448424
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
DNA Repair R-HSA-73894
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
FCERI mediated MAPK activation R-HSA-2871796
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
NRIF signals cell death from the nucleus R-HSA-205043
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Nervous system development R-HSA-9675108
p75 NTR receptor-mediated signalling R-HSA-193704
Axon guidance R-HSA-422475
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cytokine Signaling in Immune system R-HSA-1280215
Activation of the AP-1 family of transcription factors R-HSA-450341
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Developmental Biology R-HSA-1266738
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Programmed Cell Death R-HSA-5357801
Cellular Senescence R-HSA-2559583
Axon guidance R-HSA-422475
Oxidative Stress Induced Senescence R-HSA-2559580
Death Receptor Signaling R-HSA-73887
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
DNA Repair R-HSA-73894
Nervous system development R-HSA-9675108
Cellular responses to stress R-HSA-2262752
Netrin-1 signaling R-HSA-373752
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Innate Immune System R-HSA-168249
Activation of BIM and translocation to mitochondria R-HSA-111446
Programmed Cell Death R-HSA-5357801
Signal Transduction R-HSA-162582
Killing mechanisms R-HSA-9664420
Immune System R-HSA-168256
FCERI mediated MAPK activation R-HSA-2871796
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Apoptosis R-HSA-109581
Interleukin-17 signaling R-HSA-448424
MyD88-independent TLR4 cascade R-HSA-166166
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Leishmania infection R-HSA-9658195
Cytokine Signaling in Immune system R-HSA-1280215
NRAGE signals death through JNK R-HSA-193648
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
p75 NTR receptor-mediated signalling R-HSA-193704
MyD88 dependent cascade initiated on endosome R-HSA-975155
MAP kinase activation R-HSA-450294
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Intrinsic Pathway for Apoptosis R-HSA-109606
Disease R-HSA-1643685
Interleukin-38 signaling R-HSA-9007892
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll-like Receptor Cascades R-HSA-168898
Signaling by Interleukins R-HSA-449147
NRIF signals cell death from the nucleus R-HSA-205043
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of BMF and translocation to mitochondria R-HSA-139910
Developmental Biology R-HSA-1266738
DNA Double-Strand Break Repair R-HSA-5693532
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Infectious disease R-HSA-5663205
Activation of BH3-only proteins R-HSA-114452
Activation of the AP-1 family of transcription factors R-HSA-450341
Cellular responses to stimuli R-HSA-8953897
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
DNA Double Strand Break Response R-HSA-5693606
DSCAM interactions R-HSA-376172
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Signaling by Interleukins R-HSA-449147
Leishmania infection R-HSA-9658195
DNA Double-Strand Break Repair R-HSA-5693532
Activation of BMF and translocation to mitochondria R-HSA-139910
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
NRAGE signals death through JNK R-HSA-193648
Toll-like Receptor Cascades R-HSA-168898
Activation of the AP-1 family of transcription factors R-HSA-450341
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Interleukin-17 signaling R-HSA-448424
Netrin-1 signaling R-HSA-373752
MyD88 cascade initiated on plasma membrane R-HSA-975871
Axon guidance R-HSA-422475
Cellular Senescence R-HSA-2559583
Activation of BH3-only proteins R-HSA-114452
Apoptosis R-HSA-109581
Interleukin-38 signaling R-HSA-9007892
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Cytokine Signaling in Immune system R-HSA-1280215
MAP kinase activation R-HSA-450294
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Interleukin-1 family signaling R-HSA-446652
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88-independent TLR4 cascade R-HSA-166166
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Developmental Biology R-HSA-1266738
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
p75 NTR receptor-mediated signalling R-HSA-193704
DNA Repair R-HSA-73894
Intrinsic Pathway for Apoptosis R-HSA-109606
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Programmed Cell Death R-HSA-5357801
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stress R-HSA-2262752
Immune System R-HSA-168256
Killing mechanisms R-HSA-9664420
Nervous system development R-HSA-9675108
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Activation of BIM and translocation to mitochondria R-HSA-111446
DSCAM interactions R-HSA-376172
NRIF signals cell death from the nucleus R-HSA-205043
Infectious disease R-HSA-5663205
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Disease R-HSA-1643685
DNA Double Strand Break Response R-HSA-5693606
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
DNA Repair R-HSA-73894
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Innate Immune System R-HSA-168249
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by Interleukins R-HSA-449147
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Leishmania infection R-HSA-9658195
NRAGE signals death through JNK R-HSA-193648
Interleukin-38 signaling R-HSA-9007892
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Immune System R-HSA-168256
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DNA Double Strand Break Response R-HSA-5693606
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MyD88 dependent cascade initiated on endosome R-HSA-975155
Netrin-1 signaling R-HSA-373752
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Interleukin-1 family signaling R-HSA-446652
MyD88-independent TLR4 cascade R-HSA-166166
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
MAP kinase activation R-HSA-450294
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
DSCAM interactions R-HSA-376172
Apoptosis R-HSA-109581
Disease R-HSA-1643685
DNA Double-Strand Break Repair R-HSA-5693532
FCERI mediated MAPK activation R-HSA-2871796
Nervous system development R-HSA-9675108
Activation of BIM and translocation to mitochondria R-HSA-111446
Activation of BMF and translocation to mitochondria R-HSA-139910
NRIF signals cell death from the nucleus R-HSA-205043
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Programmed Cell Death R-HSA-5357801
Interleukin-17 signaling R-HSA-448424
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Killing mechanisms R-HSA-9664420
Cytokine Signaling in Immune system R-HSA-1280215
Cellular Senescence R-HSA-2559583
Activation of the AP-1 family of transcription factors R-HSA-450341
Oxidative Stress Induced Senescence R-HSA-2559580
Activation of BH3-only proteins R-HSA-114452
Cellular responses to stress R-HSA-2262752
Toll-like Receptor Cascades R-HSA-168898
Infectious disease R-HSA-5663205
Killing mechanisms R-HSA-9664420
Developmental Biology R-HSA-1266738
Intrinsic Pathway for Apoptosis R-HSA-109606
Interleukin-38 signaling R-HSA-9007892
p75 NTR receptor-mediated signalling R-HSA-193704
Cellular Senescence R-HSA-2559583
Activation of BMF and translocation to mitochondria R-HSA-139910
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Nervous system development R-HSA-9675108
DNA Repair R-HSA-73894
Programmed Cell Death R-HSA-5357801
Cellular responses to stress R-HSA-2262752
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Innate Immune System R-HSA-168249
Leishmania infection R-HSA-9658195
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Axon guidance R-HSA-422475
Netrin-1 signaling R-HSA-373752
Oxidative Stress Induced Senescence R-HSA-2559580
Disease R-HSA-1643685
DNA Double Strand Break Response R-HSA-5693606
DSCAM interactions R-HSA-376172
Cellular responses to stimuli R-HSA-8953897
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
FCERI mediated MAPK activation R-HSA-2871796
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
MyD88-independent TLR4 cascade R-HSA-166166
MAP kinase activation R-HSA-450294
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
NRIF signals cell death from the nucleus R-HSA-205043
DNA Double-Strand Break Repair R-HSA-5693532
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll-like Receptor Cascades R-HSA-168898
MyD88 dependent cascade initiated on endosome R-HSA-975155
Activation of BH3-only proteins R-HSA-114452
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Interleukin-17 signaling R-HSA-448424
Death Receptor Signaling R-HSA-73887
Activation of BIM and translocation to mitochondria R-HSA-111446
Interleukin-1 family signaling R-HSA-446652
Activation of the AP-1 family of transcription factors R-HSA-450341
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal Transduction R-HSA-162582
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Immune System R-HSA-168256
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
NRAGE signals death through JNK R-HSA-193648
Apoptosis R-HSA-109581
Killing mechanisms R-HSA-9664420
NRIF signals cell death from the nucleus R-HSA-205043
NRAGE signals death through JNK R-HSA-193648
p75 NTR receptor-mediated signalling R-HSA-193704
Activation of the AP-1 family of transcription factors R-HSA-450341
Immune System R-HSA-168256
DNA Double Strand Break Response R-HSA-5693606
MAP kinase activation R-HSA-450294
Activation of BH3-only proteins R-HSA-114452
Activation of BIM and translocation to mitochondria R-HSA-111446
Death Receptor Signaling R-HSA-73887
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by Interleukins R-HSA-449147
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
MyD88 cascade initiated on plasma membrane R-HSA-975871
Infectious disease R-HSA-5663205
Oxidative Stress Induced Senescence R-HSA-2559580
Programmed Cell Death R-HSA-5357801
Intrinsic Pathway for Apoptosis R-HSA-109606
Axon guidance R-HSA-422475
FCERI mediated MAPK activation R-HSA-2871796
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Activation of BMF and translocation to mitochondria R-HSA-139910
Interleukin-17 signaling R-HSA-448424
Disease R-HSA-1643685
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signal Transduction R-HSA-162582
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Nervous system development R-HSA-9675108
Leishmania infection R-HSA-9658195
Developmental Biology R-HSA-1266738
Interleukin-38 signaling R-HSA-9007892
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular Senescence R-HSA-2559583
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DNA Double-Strand Break Repair R-HSA-5693532
Apoptosis R-HSA-109581
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
DSCAM interactions R-HSA-376172
WNT5:FZD7-mediated leishmania damping R-HSA-9673324
Toll-like Receptor Cascades R-HSA-168898
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Cellular responses to stress R-HSA-2262752
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
DNA Repair R-HSA-73894
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Netrin-1 signaling R-HSA-373752
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Innate Immune System R-HSA-168249
Activation of BMF and translocation to mitochondria R-HSA-139910
Activation of BIM and translocation to mitochondria R-HSA-111446
Interleukin-1 family signaling R-HSA-446652
p75 NTR receptor-mediated signalling R-HSA-193704
Innate Immune System R-HSA-168249
Cellular responses to stress R-HSA-2262752
Activation of BH3-only proteins R-HSA-114452
Activation of the AP-1 family of transcription factors R-HSA-450341
DNA Double-Strand Break Repair R-HSA-5693532
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Interleukins R-HSA-449147
DNA Repair R-HSA-73894
Netrin-1 signaling R-HSA-373752
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll-like Receptor Cascades R-HSA-168898
NRAGE signals death through JNK R-HSA-193648
Disease R-HSA-1643685
MAP kinase activation R-HSA-450294
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Leishmania infection R-HSA-9658195
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
DSCAM interactions R-HSA-376172
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Killing mechanisms R-HSA-9664420
Intrinsic Pathway for Apoptosis R-HSA-109606
DNA Double Strand Break Response R-HSA-5693606
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal Transduction R-HSA-162582
MyD88-independent TLR4 cascade R-HSA-166166
Cellular Senescence R-HSA-2559583
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-38 signaling R-HSA-9007892
Apoptosis R-HSA-109581
NRIF signals cell death from the nucleus R-HSA-205043
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
FCERI mediated MAPK activation R-HSA-2871796
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Programmed Cell Death R-HSA-5357801
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Nervous system development R-HSA-9675108
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Infectious disease R-HSA-5663205
Immune System R-HSA-168256
Developmental Biology R-HSA-1266738
Death Receptor Signaling R-HSA-73887
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88 dependent cascade initiated on endosome R-HSA-975155
Axon guidance R-HSA-422475
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-17 signaling R-HSA-448424
WNT5:FZD7-mediated leishmania damping R-HSA-9673324

Expression Atlas ENSG00000107643
NCBI gene (formerly Entrezgene) 5599
GeneCards 6881
HGNC Symbol HGNC:6881
MIM gene 601158
UniProtKB Gene Name P45983
WikiGene 5599
Gene: ACVRL1
Ensembl ID : ENSG00000139567
Description: activin A receptor like type 1
Gene Synonyms: ACVRLK1,ALK1,HHT,HHT2,ORW2
2 APIs:
358 Possible Orthologues:

Signal Transduction R-HSA-162582
Signaling by BMP R-HSA-201451
Signaling by TGFB family members R-HSA-9006936
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signaling by TGFB family members R-HSA-9006936
Signal Transduction R-HSA-162582
Signaling by BMP R-HSA-201451
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signal Transduction R-HSA-162582
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000139567
LRG display in Ensembl gene LRG_543
NCBI gene (formerly Entrezgene) 94
GeneCards 175
HGNC Symbol HGNC:175
MIM gene 601284
MIM morbid 600376
UniProtKB Gene Name P37023
WikiGene 94