Gene: CDK4
Ensembl ID : ENSG00000135446
Description: cyclin dependent kinase 4
Gene Synonyms: PSK-J3
15 APIs:
227 Possible Orthologues:

Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Developmental Biology R-HSA-1266738
PTK6 Regulates Cell Cycle R-HSA-8849470
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RMTs methylate histone arginines R-HSA-3214858
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Meiotic recombination R-HSA-912446
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stimuli R-HSA-8953897
G1/S Transition R-HSA-69206
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Transcriptional regulation of granulopoiesis R-HSA-9616222
Chromatin modifying enzymes R-HSA-3247509
Cell Cycle R-HSA-1640170
Cyclin E associated events during G1/S transition R-HSA-69202
Signal Transduction R-HSA-162582
G1 Phase R-HSA-69236
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Diseases of cellular response to stress R-HSA-9675132
Cellular responses to stress R-HSA-2262752
Oncogene Induced Senescence R-HSA-2559585
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Reproduction R-HSA-1474165
Diseases of mitotic cell cycle R-HSA-9675126
S Phase R-HSA-69242
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
RNA Polymerase II Transcription R-HSA-73857
Chromatin organization R-HSA-4839726
Diseases of Cellular Senescence R-HSA-9630747
Cyclin D associated events in G1 R-HSA-69231
Signaling by PTK6 R-HSA-8848021
Meiosis R-HSA-1500620
Oxidative Stress Induced Senescence R-HSA-2559580
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Cellular Senescence R-HSA-2559583
Generic Transcription Pathway R-HSA-212436
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Gene expression (Transcription) R-HSA-74160
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX2 R-HSA-8878166
Diseases of mitotic cell cycle R-HSA-9675126
Signal Transduction R-HSA-162582
Cyclin E associated events during G1/S transition R-HSA-69202
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
G1 Phase R-HSA-69236
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cellular responses to stimuli R-HSA-8953897
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Cell Cycle, Mitotic R-HSA-69278
Signaling by PTK6 R-HSA-8848021
Cell Cycle R-HSA-1640170
Oxidative Stress Induced Senescence R-HSA-2559580
G1/S Transition R-HSA-69206
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cyclin D associated events in G1 R-HSA-69231
Cellular Senescence R-HSA-2559583
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
PTK6 Regulates Cell Cycle R-HSA-8849470
Meiotic recombination R-HSA-912446
Transcriptional regulation of granulopoiesis R-HSA-9616222
Meiosis R-HSA-1500620
Mitotic G1 phase and G1/S transition R-HSA-453279
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
RMTs methylate histone arginines R-HSA-3214858
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Gene expression (Transcription) R-HSA-74160
Oncogene Induced Senescence R-HSA-2559585
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Disease R-HSA-1643685
S Phase R-HSA-69242
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Chromatin modifying enzymes R-HSA-3247509
Diseases of Cellular Senescence R-HSA-9630747
Chromatin organization R-HSA-4839726
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RNA Polymerase II Transcription R-HSA-73857
Reproduction R-HSA-1474165
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Diseases of cellular response to stress R-HSA-9675132
Oxidative Stress Induced Senescence R-HSA-2559580
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Diseases of mitotic cell cycle R-HSA-9675126
Mitotic G1 phase and G1/S transition R-HSA-453279
Generic Transcription Pathway R-HSA-212436
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Disease R-HSA-1643685
Chromatin modifying enzymes R-HSA-3247509
Cyclin E associated events during G1/S transition R-HSA-69202
PTK6 Regulates Cell Cycle R-HSA-8849470
G1/S Transition R-HSA-69206
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cellular Senescence R-HSA-2559583
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Chromatin organization R-HSA-4839726
Signal Transduction R-HSA-162582
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Diseases of cellular response to stress R-HSA-9675132
RMTs methylate histone arginines R-HSA-3214858
G1 Phase R-HSA-69236
Meiosis R-HSA-1500620
RNA Polymerase II Transcription R-HSA-73857
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Gene expression (Transcription) R-HSA-74160
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Signaling by PTK6 R-HSA-8848021
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Meiotic recombination R-HSA-912446
Reproduction R-HSA-1474165
Cyclin D associated events in G1 R-HSA-69231
Cell Cycle R-HSA-1640170
Transcriptional regulation of granulopoiesis R-HSA-9616222
Oncogene Induced Senescence R-HSA-2559585
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Diseases of Cellular Senescence R-HSA-9630747
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
S Phase R-HSA-69242
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Reproduction R-HSA-1474165
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Gene expression (Transcription) R-HSA-74160
Diseases of mitotic cell cycle R-HSA-9675126
Mitotic G1 phase and G1/S transition R-HSA-453279
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
PTK6 Regulates Cell Cycle R-HSA-8849470
Signal Transduction R-HSA-162582
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Disease R-HSA-1643685
Oncogene Induced Senescence R-HSA-2559585
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Diseases of cellular response to stress R-HSA-9675132
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of Cellular Senescence R-HSA-9630747
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Chromatin organization R-HSA-4839726
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cyclin D associated events in G1 R-HSA-69231
Meiosis R-HSA-1500620
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Transcriptional regulation of granulopoiesis R-HSA-9616222
RNA Polymerase II Transcription R-HSA-73857
Meiotic recombination R-HSA-912446
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stimuli R-HSA-8953897
G1/S Transition R-HSA-69206
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
S Phase R-HSA-69242
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
RMTs methylate histone arginines R-HSA-3214858
Cell Cycle R-HSA-1640170
G1 Phase R-HSA-69236
Cellular Senescence R-HSA-2559583
Chromatin modifying enzymes R-HSA-3247509
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle, Mitotic R-HSA-69278
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Signaling by PTK6 R-HSA-8848021
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Cyclin E associated events during G1/S transition R-HSA-69202
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
Reproduction R-HSA-1474165
Cyclin D associated events in G1 R-HSA-69231
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Meiotic recombination R-HSA-912446
Diseases of cellular response to stress R-HSA-9675132
Transcriptional regulation of granulopoiesis R-HSA-9616222
Cellular responses to stress R-HSA-2262752
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Oncogene Induced Senescence R-HSA-2559585
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Cell Cycle R-HSA-1640170
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of Cellular Senescence R-HSA-9630747
Chromatin modifying enzymes R-HSA-3247509
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular Senescence R-HSA-2559583
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G1 Phase R-HSA-69236
RMTs methylate histone arginines R-HSA-3214858
Signal Transduction R-HSA-162582
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
PTK6 Regulates Cell Cycle R-HSA-8849470
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S Transition R-HSA-69206
Diseases of mitotic cell cycle R-HSA-9675126
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Signaling by PTK6 R-HSA-8848021
Meiosis R-HSA-1500620
Cellular responses to stimuli R-HSA-8953897
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Chromatin organization R-HSA-4839726
Oxidative Stress Induced Senescence R-HSA-2559580
Gene expression (Transcription) R-HSA-74160
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Cyclin E associated events during G1/S transition R-HSA-69202
G1/S Transition R-HSA-69206
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cellular Senescence R-HSA-2559583
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Reproduction R-HSA-1474165
Generic Transcription Pathway R-HSA-212436
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Meiosis R-HSA-1500620
Cell Cycle R-HSA-1640170
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Chromatin organization R-HSA-4839726
Cellular responses to stimuli R-HSA-8953897
G1 Phase R-HSA-69236
Diseases of mitotic cell cycle R-HSA-9675126
Diseases of cellular response to stress R-HSA-9675132
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Developmental Biology R-HSA-1266738
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Diseases of Cellular Senescence R-HSA-9630747
Cellular responses to stress R-HSA-2262752
Signaling by PTK6 R-HSA-8848021
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX2 R-HSA-8878166
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Oncogene Induced Senescence R-HSA-2559585
Transcriptional regulation of granulopoiesis R-HSA-9616222
Meiotic recombination R-HSA-912446
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Disease R-HSA-1643685
Chromatin modifying enzymes R-HSA-3247509
Oxidative Stress Induced Senescence R-HSA-2559580
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Cyclin D associated events in G1 R-HSA-69231
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
S Phase R-HSA-69242
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PTK6 Regulates Cell Cycle R-HSA-8849470
RNA Polymerase II Transcription R-HSA-73857
RMTs methylate histone arginines R-HSA-3214858
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S Transition R-HSA-69206
Oncogene Induced Senescence R-HSA-2559585
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Gene expression (Transcription) R-HSA-74160
Mitotic G1 phase and G1/S transition R-HSA-453279
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
RMTs methylate histone arginines R-HSA-3214858
Reproduction R-HSA-1474165
Signal Transduction R-HSA-162582
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Cellular responses to stress R-HSA-2262752
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin D associated events in G1 R-HSA-69231
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Chromatin organization R-HSA-4839726
PTK6 Regulates Cell Cycle R-HSA-8849470
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Diseases of cellular response to stress R-HSA-9675132
Developmental Biology R-HSA-1266738
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Cellular Senescence R-HSA-2559583
Meiotic recombination R-HSA-912446
Cellular responses to stimuli R-HSA-8953897
Chromatin modifying enzymes R-HSA-3247509
Transcriptional regulation of granulopoiesis R-HSA-9616222
Meiosis R-HSA-1500620
Diseases of mitotic cell cycle R-HSA-9675126
Diseases of Cellular Senescence R-HSA-9630747
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
S Phase R-HSA-69242
Signaling by PTK6 R-HSA-8848021
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G1 Phase R-HSA-69236
Oxidative Stress Induced Senescence R-HSA-2559580
Oxidative Stress Induced Senescence R-HSA-2559580
Diseases of cellular response to stress R-HSA-9675132
Cell Cycle, Mitotic R-HSA-69278
Meiosis R-HSA-1500620
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Diseases of Cellular Senescence R-HSA-9630747
S Phase R-HSA-69242
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by PTK6 R-HSA-8848021
G1/S Transition R-HSA-69206
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Cellular Senescence R-HSA-2559583
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Mitotic G1 phase and G1/S transition R-HSA-453279
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Cell Cycle R-HSA-1640170
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
Oncogene Induced Senescence R-HSA-2559585
Transcriptional regulation of granulopoiesis R-HSA-9616222
Chromatin organization R-HSA-4839726
Cyclin E associated events during G1/S transition R-HSA-69202
G1 Phase R-HSA-69236
Reproduction R-HSA-1474165
PTK6 Regulates Cell Cycle R-HSA-8849470
Chromatin modifying enzymes R-HSA-3247509
Meiotic recombination R-HSA-912446
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Cyclin D associated events in G1 R-HSA-69231
Developmental Biology R-HSA-1266738
RMTs methylate histone arginines R-HSA-3214858
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX2 R-HSA-8878166
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cellular responses to stimuli R-HSA-8953897
Diseases of mitotic cell cycle R-HSA-9675126
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Gene expression (Transcription) R-HSA-74160
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Signaling by PTK6 R-HSA-8848021
Developmental Biology R-HSA-1266738
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
PTK6 Regulates Cell Cycle R-HSA-8849470
Cyclin E associated events during G1/S transition R-HSA-69202
Meiotic recombination R-HSA-912446
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle, Mitotic R-HSA-69278
Oxidative Stress Induced Senescence R-HSA-2559580
Chromatin modifying enzymes R-HSA-3247509
Reproduction R-HSA-1474165
Diseases of Cellular Senescence R-HSA-9630747
S Phase R-HSA-69242
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
G1 Phase R-HSA-69236
Cellular responses to stimuli R-HSA-8953897
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Transcriptional regulation of granulopoiesis R-HSA-9616222
RNA Polymerase II Transcription R-HSA-73857
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Cellular Senescence R-HSA-2559583
Diseases of mitotic cell cycle R-HSA-9675126
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cell Cycle R-HSA-1640170
Cellular responses to stress R-HSA-2262752
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
Meiosis R-HSA-1500620
RMTs methylate histone arginines R-HSA-3214858
Chromatin organization R-HSA-4839726
Signal Transduction R-HSA-162582
Oncogene Induced Senescence R-HSA-2559585
Diseases of cellular response to stress R-HSA-9675132
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
G1/S Transition R-HSA-69206
Cyclin D associated events in G1 R-HSA-69231
Transcriptional regulation by RUNX2 R-HSA-8878166
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cell Cycle R-HSA-1640170
Meiosis R-HSA-1500620
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750
Diseases of Cellular Senescence R-HSA-9630747
Cell Cycle, Mitotic R-HSA-69278
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cyclin D associated events in G1 R-HSA-69231
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Oncogene Induced Senescence R-HSA-2559585
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700
RNA Polymerase II Transcription R-HSA-73857
RMTs methylate histone arginines R-HSA-3214858
PTK6 Regulates Cell Cycle R-HSA-8849470
G1 Phase R-HSA-69236
Gene expression (Transcription) R-HSA-74160
Chromatin organization R-HSA-4839726
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
S Phase R-HSA-69242
Meiotic recombination R-HSA-912446
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S Transition R-HSA-69206
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Transcriptional regulation of granulopoiesis R-HSA-9616222
Chromatin modifying enzymes R-HSA-3247509
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693
Reproduction R-HSA-1474165
Developmental Biology R-HSA-1266738
Signaling by PTK6 R-HSA-8848021
Cellular Senescence R-HSA-2559583
Diseases of cellular response to stress R-HSA-9675132
Cellular responses to stress R-HSA-2262752
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697
Signal Transduction R-HSA-162582
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Mitotic G1 phase and G1/S transition R-HSA-453279
Oxidative Stress Induced Senescence R-HSA-2559580
Generic Transcription Pathway R-HSA-212436
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stimuli R-HSA-8953897
Diseases of mitotic cell cycle R-HSA-9675126
Disease R-HSA-1643685

Expression Atlas ENSG00000135446
LRG display in Ensembl gene LRG_490
NCBI gene (formerly Entrezgene) 1019
GeneCards 1773
HGNC Symbol HGNC:1773
MIM gene 123829
MIM morbid 609048
UniProtKB Gene Name Q96BE9
WikiGene 1019
Gene: TEK
Ensembl ID : ENSG00000120156
Description: TEK receptor tyrosine kinase
Gene Synonyms: CD202B,TIE-2,TIE2,VMCM,VMCM1
8 APIs:
166 Possible Orthologues:

Signal Transduction R-HSA-162582
Cell surface interactions at the vascular wall R-HSA-202733
Tie2 Signaling R-HSA-210993
Hemostasis R-HSA-109582
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
Cell surface interactions at the vascular wall R-HSA-202733
MAPK1/MAPK3 signaling R-HSA-5684996
Tie2 Signaling R-HSA-210993
MAPK family signaling cascades R-HSA-5683057
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Tie2 Signaling R-HSA-210993
MAPK family signaling cascades R-HSA-5683057
Hemostasis R-HSA-109582
RAF/MAP kinase cascade R-HSA-5673001
Cell surface interactions at the vascular wall R-HSA-202733
MAPK1/MAPK3 signaling R-HSA-5684996
Cell surface interactions at the vascular wall R-HSA-202733
Tie2 Signaling R-HSA-210993
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Hemostasis R-HSA-109582
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
MAPK1/MAPK3 signaling R-HSA-5684996
Cell surface interactions at the vascular wall R-HSA-202733
Hemostasis R-HSA-109582
Tie2 Signaling R-HSA-210993
Cell surface interactions at the vascular wall R-HSA-202733
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
Tie2 Signaling R-HSA-210993
Tie2 Signaling R-HSA-210993
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Cell surface interactions at the vascular wall R-HSA-202733
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
Hemostasis R-HSA-109582
RAF/MAP kinase cascade R-HSA-5673001
Hemostasis R-HSA-109582
Tie2 Signaling R-HSA-210993
Cell surface interactions at the vascular wall R-HSA-202733
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
RAF/MAP kinase cascade R-HSA-5673001
Tie2 Signaling R-HSA-210993
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
Cell surface interactions at the vascular wall R-HSA-202733
Signal Transduction R-HSA-162582
Hemostasis R-HSA-109582
Hemostasis R-HSA-109582
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Tie2 Signaling R-HSA-210993
Cell surface interactions at the vascular wall R-HSA-202733

Expression Atlas ENSG00000120156
NCBI gene (formerly Entrezgene) 7010
GeneCards 11724
HGNC Symbol HGNC:11724
MIM gene 600221
MIM morbid 617272
UniProtKB Gene Name Q02763
WikiGene 7010
Gene: TTK
Ensembl ID : ENSG00000112742
Description: TTK protein kinase
Gene Synonyms: CT96,MPH1,MPS1,MPS1L1
2 APIs:
204 Possible Orthologues:

Expression Atlas ENSG00000112742
NCBI gene (formerly Entrezgene) 7272
GeneCards 12401
HGNC Symbol HGNC:12401
MIM gene 604092
UniProtKB Gene Name P33981
WikiGene 7272
Gene: PIM3
Ensembl ID : ENSG00000198355
Description: Pim-3 proto-oncogene, serine/threonine kinase
Gene Synonyms:
3 APIs:
196 Possible Orthologues:

Expression Atlas ENSG00000198355
NCBI gene (formerly Entrezgene) 415116
GeneCards 19310
HGNC Symbol HGNC:19310
MIM gene 610580
UniProtKB Gene Name Q86V86
WikiGene 415116
Gene: CCND1
Ensembl ID : ENSG00000110092
Description: cyclin D1
Gene Synonyms: BCL1,D11S287E,PRAD1,U21B31
1 APIs:
274 Possible Orthologues:

Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Diseases of mitotic cell cycle R-HSA-9675126
Pre-NOTCH Transcription and Translation R-HSA-1912408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Chromatin organization R-HSA-4839726
Transcriptional Regulation by VENTX R-HSA-8853884
Generic Transcription Pathway R-HSA-212436
RMTs methylate histone arginines R-HSA-3214858
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Disease R-HSA-1643685
Estrogen-dependent gene expression R-HSA-9018519
Pre-NOTCH Expression and Processing R-HSA-1912422
Cytokine Signaling in Immune system R-HSA-1280215
Extra-nuclear estrogen signaling R-HSA-9009391
Immune System R-HSA-168256
ESR-mediated signaling R-HSA-8939211
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Signaling by Nuclear Receptors R-HSA-9006931
G1 Phase R-HSA-69236
Cyclin D associated events in G1 R-HSA-69231
G1/S Transition R-HSA-69206
Cell Cycle, Mitotic R-HSA-69278
S Phase R-HSA-69242
Mitotic G1 phase and G1/S transition R-HSA-453279
RNA Polymerase II Transcription R-HSA-73857
PTK6 Regulates Cell Cycle R-HSA-8849470
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cell Cycle R-HSA-1640170
Signaling by NOTCH R-HSA-157118
Signaling by PTK6 R-HSA-8848021
Chromatin modifying enzymes R-HSA-3247509
RUNX3 regulates p14-ARF R-HSA-8951936
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Gene expression (Transcription) R-HSA-74160
RUNX3 regulates WNT signaling R-HSA-8951430
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX1 R-HSA-8878171
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX3 R-HSA-8878159
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Signaling by Interleukins R-HSA-449147
Disease R-HSA-1643685
Signaling by Nuclear Receptors R-HSA-9006931
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
S Phase R-HSA-69242
Gene expression (Transcription) R-HSA-74160
PTK6 Regulates Cell Cycle R-HSA-8849470
Transcriptional Regulation by VENTX R-HSA-8853884
RMTs methylate histone arginines R-HSA-3214858
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Cell Cycle R-HSA-1640170
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RUNX3 regulates WNT signaling R-HSA-8951430
Pre-NOTCH Expression and Processing R-HSA-1912422
Transcriptional regulation by RUNX3 R-HSA-8878159
G1 Phase R-HSA-69236
Transcriptional regulation by RUNX1 R-HSA-8878171
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cyclin E associated events during G1/S transition R-HSA-69202
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Signaling by NOTCH R-HSA-157118
RNA Polymerase II Transcription R-HSA-73857
Signaling by PTK6 R-HSA-8848021
G1/S Transition R-HSA-69206
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Chromatin modifying enzymes R-HSA-3247509
Pre-NOTCH Transcription and Translation R-HSA-1912408
Cell Cycle, Mitotic R-HSA-69278
Estrogen-dependent gene expression R-HSA-9018519
Extra-nuclear estrogen signaling R-HSA-9009391
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cyclin D associated events in G1 R-HSA-69231
Chromatin organization R-HSA-4839726
Generic Transcription Pathway R-HSA-212436
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
RUNX3 regulates p14-ARF R-HSA-8951936
Mitotic G1 phase and G1/S transition R-HSA-453279
Signal Transduction R-HSA-162582
ESR-mediated signaling R-HSA-8939211
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of mitotic cell cycle R-HSA-9675126
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Chromatin modifying enzymes R-HSA-3247509
S Phase R-HSA-69242
Mitotic G1 phase and G1/S transition R-HSA-453279
RMTs methylate histone arginines R-HSA-3214858
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Transcriptional regulation by RUNX1 R-HSA-8878171
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Transcriptional Regulation by VENTX R-HSA-8853884
ESR-mediated signaling R-HSA-8939211
Transcriptional regulation by RUNX3 R-HSA-8878159
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Diseases of mitotic cell cycle R-HSA-9675126
Generic Transcription Pathway R-HSA-212436
Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cytokine Signaling in Immune system R-HSA-1280215
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin D associated events in G1 R-HSA-69231
RUNX3 regulates WNT signaling R-HSA-8951430
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RUNX3 regulates p14-ARF R-HSA-8951936
Signaling by PTK6 R-HSA-8848021
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
G1 Phase R-HSA-69236
Extra-nuclear estrogen signaling R-HSA-9009391
Estrogen-dependent gene expression R-HSA-9018519
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
RNA Polymerase II Transcription R-HSA-73857
G1/S Transition R-HSA-69206
PTK6 Regulates Cell Cycle R-HSA-8849470
Signaling by NOTCH R-HSA-157118
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Pre-NOTCH Transcription and Translation R-HSA-1912408
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
Disease R-HSA-1643685
Pre-NOTCH Expression and Processing R-HSA-1912422
Chromatin organization R-HSA-4839726
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Cyclin D associated events in G1 R-HSA-69231
ESR-mediated signaling R-HSA-8939211
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
RUNX3 regulates p14-ARF R-HSA-8951936
RNA Polymerase II Transcription R-HSA-73857
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Transcriptional regulation by RUNX1 R-HSA-8878171
Chromatin organization R-HSA-4839726
RUNX3 regulates WNT signaling R-HSA-8951430
Generic Transcription Pathway R-HSA-212436
Estrogen-dependent gene expression R-HSA-9018519
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Diseases of mitotic cell cycle R-HSA-9675126
RMTs methylate histone arginines R-HSA-3214858
Signaling by Nuclear Receptors R-HSA-9006931
Pre-NOTCH Expression and Processing R-HSA-1912422
Chromatin modifying enzymes R-HSA-3247509
Signaling by NOTCH R-HSA-157118
G1/S Transition R-HSA-69206
S Phase R-HSA-69242
Gene expression (Transcription) R-HSA-74160
PTK6 Regulates Cell Cycle R-HSA-8849470
Disease R-HSA-1643685
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Transcriptional Regulation by VENTX R-HSA-8853884
Extra-nuclear estrogen signaling R-HSA-9009391
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Pre-NOTCH Transcription and Translation R-HSA-1912408
Transcriptional regulation by RUNX2 R-HSA-8878166
G1 Phase R-HSA-69236
Signaling by PTK6 R-HSA-8848021
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cell Cycle, Mitotic R-HSA-69278
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signal Transduction R-HSA-162582
Cell Cycle R-HSA-1640170
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by Interleukins R-HSA-449147
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
G1/S Transition R-HSA-69206
PTK6 Regulates Cell Cycle R-HSA-8849470
Estrogen-dependent gene expression R-HSA-9018519
Pre-NOTCH Expression and Processing R-HSA-1912422
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Transcriptional Regulation by VENTX R-HSA-8853884
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Gene expression (Transcription) R-HSA-74160
G1 Phase R-HSA-69236
Diseases of mitotic cell cycle R-HSA-9675126
RUNX3 regulates WNT signaling R-HSA-8951430
Mitotic G1 phase and G1/S transition R-HSA-453279
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Transcriptional regulation by RUNX3 R-HSA-8878159
ESR-mediated signaling R-HSA-8939211
RMTs methylate histone arginines R-HSA-3214858
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Disease R-HSA-1643685
RUNX3 regulates p14-ARF R-HSA-8951936
Pre-NOTCH Transcription and Translation R-HSA-1912408
Chromatin modifying enzymes R-HSA-3247509
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Transcriptional regulation by RUNX2 R-HSA-8878166
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by NOTCH R-HSA-157118
Chromatin organization R-HSA-4839726
Signaling by PTK6 R-HSA-8848021
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signal Transduction R-HSA-162582
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cyclin D associated events in G1 R-HSA-69231
Signaling by Nuclear Receptors R-HSA-9006931
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
S Phase R-HSA-69242
Extra-nuclear estrogen signaling R-HSA-9009391
Cytokine Signaling in Immune system R-HSA-1280215
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Cyclin E associated events during G1/S transition R-HSA-69202
Generic Transcription Pathway R-HSA-212436
Signaling by Interleukins R-HSA-449147
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by PTK6 R-HSA-8848021
Disease R-HSA-1643685
Transcriptional regulation by RUNX1 R-HSA-8878171
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by NOTCH R-HSA-157118
Transcriptional regulation by RUNX3 R-HSA-8878159
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Transcriptional Regulation by VENTX R-HSA-8853884
Chromatin organization R-HSA-4839726
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Pre-NOTCH Expression and Processing R-HSA-1912422
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1 Phase R-HSA-69236
RUNX3 regulates p14-ARF R-HSA-8951936
S Phase R-HSA-69242
ESR-mediated signaling R-HSA-8939211
Signaling by Nuclear Receptors R-HSA-9006931
Chromatin modifying enzymes R-HSA-3247509
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Immune System R-HSA-168256
Pre-NOTCH Transcription and Translation R-HSA-1912408
RMTs methylate histone arginines R-HSA-3214858
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle, Mitotic R-HSA-69278
G1/S Transition R-HSA-69206
Extra-nuclear estrogen signaling R-HSA-9009391
Cell Cycle R-HSA-1640170
Mitotic G1 phase and G1/S transition R-HSA-453279
Cyclin D associated events in G1 R-HSA-69231
RNA Polymerase II Transcription R-HSA-73857
Diseases of mitotic cell cycle R-HSA-9675126
Estrogen-dependent gene expression R-HSA-9018519
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
RUNX3 regulates WNT signaling R-HSA-8951430
Cyclin E associated events during G1/S transition R-HSA-69202
Gene expression (Transcription) R-HSA-74160
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
PTK6 Regulates Cell Cycle R-HSA-8849470
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Transcriptional regulation by RUNX3 R-HSA-8878159
Signal Transduction R-HSA-162582
RUNX3 regulates WNT signaling R-HSA-8951430
RMTs methylate histone arginines R-HSA-3214858
S Phase R-HSA-69242
G1/S Transition R-HSA-69206
RUNX3 regulates p14-ARF R-HSA-8951936
Cyclin E associated events during G1/S transition R-HSA-69202
Chromatin modifying enzymes R-HSA-3247509
PTK6 Regulates Cell Cycle R-HSA-8849470
Cell Cycle R-HSA-1640170
Signaling by NOTCH R-HSA-157118
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Pre-NOTCH Transcription and Translation R-HSA-1912408
Transcriptional Regulation by VENTX R-HSA-8853884
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Extra-nuclear estrogen signaling R-HSA-9009391
Immune System R-HSA-168256
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Gene expression (Transcription) R-HSA-74160
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Chromatin organization R-HSA-4839726
Generic Transcription Pathway R-HSA-212436
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of mitotic cell cycle R-HSA-9675126
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
ESR-mediated signaling R-HSA-8939211
Pre-NOTCH Expression and Processing R-HSA-1912422
Transcriptional regulation by RUNX2 R-HSA-8878166
Disease R-HSA-1643685
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by PTK6 R-HSA-8848021
Cyclin D associated events in G1 R-HSA-69231
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Cell Cycle, Mitotic R-HSA-69278
RNA Polymerase II Transcription R-HSA-73857
Estrogen-dependent gene expression R-HSA-9018519
Cytokine Signaling in Immune system R-HSA-1280215
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1 Phase R-HSA-69236
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by NOTCH R-HSA-157118
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Chromatin organization R-HSA-4839726
Mitotic G1 phase and G1/S transition R-HSA-453279
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Generic Transcription Pathway R-HSA-212436
RUNX3 regulates p14-ARF R-HSA-8951936
Chromatin modifying enzymes R-HSA-3247509
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Transcriptional regulation by RUNX3 R-HSA-8878159
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Disease R-HSA-1643685
Pre-NOTCH Transcription and Translation R-HSA-1912408
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX1 R-HSA-8878171
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
PTK6 Regulates Cell Cycle R-HSA-8849470
Cell Cycle, Mitotic R-HSA-69278
Gene expression (Transcription) R-HSA-74160
Signaling by Nuclear Receptors R-HSA-9006931
Cyclin D associated events in G1 R-HSA-69231
G1/S Transition R-HSA-69206
RMTs methylate histone arginines R-HSA-3214858
Transcriptional Regulation by VENTX R-HSA-8853884
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Immune System R-HSA-168256
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
S Phase R-HSA-69242
Signaling by PTK6 R-HSA-8848021
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Cyclin E associated events during G1/S transition R-HSA-69202
Signal Transduction R-HSA-162582
Pre-NOTCH Expression and Processing R-HSA-1912422
Estrogen-dependent gene expression R-HSA-9018519
Extra-nuclear estrogen signaling R-HSA-9009391
G1 Phase R-HSA-69236
RUNX3 regulates WNT signaling R-HSA-8951430
Diseases of mitotic cell cycle R-HSA-9675126
ESR-mediated signaling R-HSA-8939211
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119
Pre-NOTCH Transcription and Translation R-HSA-1912408
Signaling by Nuclear Receptors R-HSA-9006931
Cell Cycle R-HSA-1640170
Signaling by Interleukins R-HSA-449147
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Transcriptional regulation by RUNX1 R-HSA-8878171
Chromatin modifying enzymes R-HSA-3247509
Generic Transcription Pathway R-HSA-212436
Chromatin organization R-HSA-4839726
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX1 Expression and Activity R-HSA-8934593
Mitotic G1 phase and G1/S transition R-HSA-453279
Pre-NOTCH Expression and Processing R-HSA-1912422
Gene expression (Transcription) R-HSA-74160
Estrogen-dependent gene expression R-HSA-9018519
Diseases of mitotic cell cycle R-HSA-9675126
Extra-nuclear estrogen signaling R-HSA-9009391
Disease R-HSA-1643685
Cyclin E associated events during G1/S transition R-HSA-69202
RUNX3 regulates p14-ARF R-HSA-8951936
PTK6 Regulates Cell Cycle R-HSA-8849470
S Phase R-HSA-69242
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RUNX3 regulates WNT signaling R-HSA-8951430
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle, Mitotic R-HSA-69278
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
G1 Phase R-HSA-69236
ESR-mediated signaling R-HSA-8939211
Signaling by PTK6 R-HSA-8848021
RNA Polymerase II Transcription R-HSA-73857
G1/S Transition R-HSA-69206
Transcriptional Regulation by VENTX R-HSA-8853884
Signaling by NOTCH R-HSA-157118
Cyclin D associated events in G1 R-HSA-69231
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
RMTs methylate histone arginines R-HSA-3214858
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Transcriptional regulation by RUNX2 R-HSA-8878166
Immune System R-HSA-168256
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000110092
LRG display in Ensembl gene LRG_990
NCBI gene (formerly Entrezgene) 595
GeneCards 1582
HGNC Symbol HGNC:1582
MIM gene 168461
MIM morbid 254500
UniProtKB Gene Name Q6FI00
WikiGene 595
Ensembl ID : ENSG00000089022
Description: MAPK activated protein kinase 5
Gene Synonyms: MK5,PRAK
1 APIs:
179 Possible Orthologues:

Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Oxidative Stress Induced Senescence R-HSA-2559580
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
MAPK family signaling cascades R-HSA-5683057
Cellular Senescence R-HSA-2559583
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity R-HSA-5633007
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK6/MAPK4 signaling R-HSA-5687128
MAPK6/MAPK4 signaling R-HSA-5687128
Oxidative Stress Induced Senescence R-HSA-2559580
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity R-HSA-5633007
Regulation of TP53 Activity R-HSA-5633007
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stress R-HSA-2262752
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Cellular Senescence R-HSA-2559583
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity R-HSA-5633007
Oxidative Stress Induced Senescence R-HSA-2559580
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
MAPK family signaling cascades R-HSA-5683057
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Cellular Senescence R-HSA-2559583
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of TP53 Activity R-HSA-5633007
MAPK family signaling cascades R-HSA-5683057
Transcriptional Regulation by TP53 R-HSA-3700989
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
MAPK6/MAPK4 signaling R-HSA-5687128
Oxidative Stress Induced Senescence R-HSA-2559580
Transcriptional Regulation by TP53 R-HSA-3700989
MAPK family signaling cascades R-HSA-5683057
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
Oxidative Stress Induced Senescence R-HSA-2559580
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of TP53 Activity R-HSA-5633007
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Oxidative Stress Induced Senescence R-HSA-2559580
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stimuli R-HSA-8953897
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Regulation of TP53 Activity R-HSA-5633007
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583

Expression Atlas ENSG00000089022
NCBI gene (formerly Entrezgene) 8550
GeneCards 6889
HGNC Symbol HGNC:6889
MIM gene 606723
MIM morbid 619869
UniProtKB Gene Name R4GN93
WikiGene 8550
Gene: FGFR2
Ensembl ID : ENSG00000066468
Description: fibroblast growth factor receptor 2
Gene Synonyms: BEK,CD332,CEK3,CFD1,ECT1,JWS,K-SAM,KGFR,TK14,TK25
27 APIs:
218 Possible Orthologues:

Activated point mutants of FGFR2 R-HSA-2033519
PI3K Cascade R-HSA-109704
FGFR2b ligand binding and activation R-HSA-190377
FGFR2 alternative splicing R-HSA-6803529
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FGFR2c ligand binding and activation R-HSA-190375
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR in disease R-HSA-1226099
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Insulin receptor R-HSA-74752
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by FGFR R-HSA-190236
Signaling by FGFR2 IIIa TM R-HSA-8851708
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by FGFR2 R-HSA-5654738
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 amplification mutants R-HSA-2023837
FGFR2 ligand binding and activation R-HSA-190241
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
FGFR2 mutant receptor activation R-HSA-1839126
Insulin receptor signalling cascade R-HSA-74751
SHC-mediated cascade:FGFR2 R-HSA-5654699
PIP3 activates AKT signaling R-HSA-1257604
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by FGFR2 fusions R-HSA-8853333
IRS-mediated signalling R-HSA-112399
Negative regulation of the PI3K/AKT network R-HSA-199418
Negative regulation of FGFR2 signaling R-HSA-5654727
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Disease R-HSA-1643685
Signaling by FGFR2 fusions R-HSA-8853333
IRS-mediated signalling R-HSA-112399
Signaling by FGFR2 in disease R-HSA-5655253
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
FGFR2c ligand binding and activation R-HSA-190375
Insulin receptor signalling cascade R-HSA-74751
FGFR2 ligand binding and activation R-HSA-190241
FGFR2b ligand binding and activation R-HSA-190377
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Downstream signaling of activated FGFR2 R-HSA-5654696
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IGF1R signaling cascade R-HSA-2428924
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR R-HSA-190236
PI3K Cascade R-HSA-109704
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR in disease R-HSA-1226099
Negative regulation of FGFR2 signaling R-HSA-5654727
Activated point mutants of FGFR2 R-HSA-2033519
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 R-HSA-5654738
FGFR2 mutant receptor activation R-HSA-1839126
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by FGFR2 IIIa TM R-HSA-8851708
IRS-related events triggered by IGF1R R-HSA-2428928
PI-3K cascade:FGFR2 R-HSA-5654695
FGFR2 alternative splicing R-HSA-6803529
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Activated point mutants of FGFR2 R-HSA-2033519
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling of activated FGFR2 R-HSA-5654696
FGFR2 alternative splicing R-HSA-6803529
FGFR2c ligand binding and activation R-HSA-190375
Signal Transduction R-HSA-162582
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by FGFR2 IIIa TM R-HSA-8851708
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 amplification mutants R-HSA-2023837
FGFR2 ligand binding and activation R-HSA-190241
Negative regulation of the PI3K/AKT network R-HSA-199418
FGFR2 mutant receptor activation R-HSA-1839126
PI3K Cascade R-HSA-109704
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
IRS-mediated signalling R-HSA-112399
Signaling by FGFR in disease R-HSA-1226099
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR R-HSA-190236
IGF1R signaling cascade R-HSA-2428924
FGFR2b ligand binding and activation R-HSA-190377
Disease R-HSA-1643685
Signaling by Insulin receptor R-HSA-74752
PI3K/AKT Signaling in Cancer R-HSA-2219528
Insulin receptor signalling cascade R-HSA-74751
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR2 in disease R-HSA-5655253
RAF/MAP kinase cascade R-HSA-5673001
FRS-mediated FGFR2 signaling R-HSA-5654700
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 in disease R-HSA-5655253
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FGFR2 ligand binding and activation R-HSA-190241
MAPK1/MAPK3 signaling R-HSA-5684996
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR2 IIIa TM R-HSA-8851708
Disease R-HSA-1643685
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2c ligand binding and activation R-HSA-190375
Signaling by FGFR R-HSA-190236
Downstream signaling of activated FGFR2 R-HSA-5654696
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR in disease R-HSA-1226099
PI3K Cascade R-HSA-109704
IRS-mediated signalling R-HSA-112399
Insulin receptor signalling cascade R-HSA-74751
IGF1R signaling cascade R-HSA-2428924
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR2 R-HSA-5654738
PIP3 activates AKT signaling R-HSA-1257604
FRS-mediated FGFR2 signaling R-HSA-5654700
SHC-mediated cascade:FGFR2 R-HSA-5654699
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FGFR2b ligand binding and activation R-HSA-190377
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by Insulin receptor R-HSA-74752
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI-3K cascade:FGFR2 R-HSA-5654695
IRS-related events triggered by IGF1R R-HSA-2428928
MAPK family signaling cascades R-HSA-5683057
IRS-mediated signalling R-HSA-112399
PIP3 activates AKT signaling R-HSA-1257604
Signaling by FGFR2 IIIa TM R-HSA-8851708
FGFR2 ligand binding and activation R-HSA-190241
PI3K Cascade R-HSA-109704
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by FGFR2 in disease R-HSA-5655253
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2b ligand binding and activation R-HSA-190377
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR2 amplification mutants R-HSA-2023837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Signaling by FGFR in disease R-HSA-1226099
FGFR2c ligand binding and activation R-HSA-190375
RAF/MAP kinase cascade R-HSA-5673001
PI3K/AKT Signaling in Cancer R-HSA-2219528
SHC-mediated cascade:FGFR2 R-HSA-5654699
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
FRS-mediated FGFR2 signaling R-HSA-5654700
Disease R-HSA-1643685
IRS-related events triggered by IGF1R R-HSA-2428928
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
FGFR2 alternative splicing R-HSA-6803529
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR R-HSA-190236
IGF1R signaling cascade R-HSA-2428924
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 in disease R-HSA-5655253
FGFR2c ligand binding and activation R-HSA-190375
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
Negative regulation of the PI3K/AKT network R-HSA-199418
FGFR2 ligand binding and activation R-HSA-190241
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
MAPK1/MAPK3 signaling R-HSA-5684996
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 amplification mutants R-HSA-2023837
IRS-related events triggered by IGF1R R-HSA-2428928
Negative regulation of FGFR2 signaling R-HSA-5654727
RAF/MAP kinase cascade R-HSA-5673001
IRS-mediated signalling R-HSA-112399
IGF1R signaling cascade R-HSA-2428924
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by FGFR2 IIIa TM R-HSA-8851708
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR in disease R-HSA-1226099
PI3K Cascade R-HSA-109704
MAPK family signaling cascades R-HSA-5683057
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Disease R-HSA-1643685
Downstream signaling of activated FGFR2 R-HSA-5654696
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR R-HSA-190236
Intracellular signaling by second messengers R-HSA-9006925
FRS-mediated FGFR2 signaling R-HSA-5654700
FGFR2 mutant receptor activation R-HSA-1839126
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2b ligand binding and activation R-HSA-190377
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Insulin receptor signalling cascade R-HSA-74751
IGF1R signaling cascade R-HSA-2428924
PIP3 activates AKT signaling R-HSA-1257604
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K Cascade R-HSA-109704
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR R-HSA-190236
Signaling by FGFR2 amplification mutants R-HSA-2023837
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2 mutant receptor activation R-HSA-1839126
Signal Transduction R-HSA-162582
FRS-mediated FGFR2 signaling R-HSA-5654700
IRS-mediated signalling R-HSA-112399
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 IIIa TM R-HSA-8851708
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR in disease R-HSA-1226099
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Negative regulation of FGFR2 signaling R-HSA-5654727
PI3K/AKT Signaling in Cancer R-HSA-2219528
Disease R-HSA-1643685
FGFR2c ligand binding and activation R-HSA-190375
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FGFR2 ligand binding and activation R-HSA-190241
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 in disease R-HSA-5655253
IRS-related events triggered by IGF1R R-HSA-2428928
FGFR2 alternative splicing R-HSA-6803529
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling of activated FGFR2 R-HSA-5654696
Insulin receptor signalling cascade R-HSA-74751
FGFR2b ligand binding and activation R-HSA-190377
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IGF1R signaling cascade R-HSA-2428924
Activated point mutants of FGFR2 R-HSA-2033519
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 amplification mutants R-HSA-2023837
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
SHC-mediated cascade:FGFR2 R-HSA-5654699
PIP3 activates AKT signaling R-HSA-1257604
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by FGFR2 fusions R-HSA-8853333
Downstream signaling of activated FGFR2 R-HSA-5654696
FGFR2c ligand binding and activation R-HSA-190375
Negative regulation of FGFR2 signaling R-HSA-5654727
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR2 IIIa TM R-HSA-8851708
Disease R-HSA-1643685
FGFR2 ligand binding and activation R-HSA-190241
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR R-HSA-190236
PI-3K cascade:FGFR2 R-HSA-5654695
FGFR2b ligand binding and activation R-HSA-190377
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR2 in disease R-HSA-5655253
IRS-mediated signalling R-HSA-112399
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR in disease R-HSA-1226099
IRS-related events triggered by IGF1R R-HSA-2428928
PI3K Cascade R-HSA-109704
FGFR2 alternative splicing R-HSA-6803529
Signal Transduction R-HSA-162582
FGFR2 mutant receptor activation R-HSA-1839126
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 in disease R-HSA-5655253
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by FGFR2 amplification mutants R-HSA-2023837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR in disease R-HSA-1226099
Disease R-HSA-1643685
Negative regulation of FGFR2 signaling R-HSA-5654727
PIP3 activates AKT signaling R-HSA-1257604
FGFR2 mutant receptor activation R-HSA-1839126
Signaling by FGFR2 IIIa TM R-HSA-8851708
Signaling by FGFR R-HSA-190236
Signal Transduction R-HSA-162582
FGFR2b ligand binding and activation R-HSA-190377
IRS-mediated signalling R-HSA-112399
FGFR2c ligand binding and activation R-HSA-190375
IGF1R signaling cascade R-HSA-2428924
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
IRS-related events triggered by IGF1R R-HSA-2428928
PI3K Cascade R-HSA-109704
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Insulin receptor R-HSA-74752
PI-3K cascade:FGFR2 R-HSA-5654695
Negative regulation of the PI3K/AKT network R-HSA-199418
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2 ligand binding and activation R-HSA-190241
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
SHC-mediated cascade:FGFR2 R-HSA-5654699
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 IIIa TM R-HSA-8851708
SHC-mediated cascade:FGFR2 R-HSA-5654699
FGFR2b ligand binding and activation R-HSA-190377
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 in disease R-HSA-5655253
IRS-related events triggered by IGF1R R-HSA-2428928
MAPK family signaling cascades R-HSA-5683057
FGFR2c ligand binding and activation R-HSA-190375
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR2 R-HSA-5654738
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR2 fusions R-HSA-8853333
Negative regulation of FGFR2 signaling R-HSA-5654727
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR R-HSA-190236
Activated point mutants of FGFR2 R-HSA-2033519
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Disease R-HSA-1643685
PI-3K cascade:FGFR2 R-HSA-5654695
MAPK1/MAPK3 signaling R-HSA-5684996
FRS-mediated FGFR2 signaling R-HSA-5654700
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
PI3K Cascade R-HSA-109704
Signaling by FGFR in disease R-HSA-1226099
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2 ligand binding and activation R-HSA-190241
FGFR2 alternative splicing R-HSA-6803529
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS-mediated signalling R-HSA-112399

Expression Atlas ENSG00000066468
LRG display in Ensembl gene LRG_994
NCBI gene (formerly Entrezgene) 2263
GeneCards 3689
HGNC Symbol HGNC:3689
MIM gene 176943
MIM morbid 614592
UniProtKB Gene Name S4R3B2
WikiGene 2263
Gene: MAPK3
Ensembl ID : ENSG00000102882
Description: mitogen-activated protein kinase 3
Gene Synonyms: ERK1,P44ERK1,P44MAPK,PRKM3
6 APIs:
199 Possible Orthologues:

ERK/MAPK targets R-HSA-198753
M Phase R-HSA-68886
Disease R-HSA-1643685
Signaling by RAS mutants R-HSA-6802949
Signaling by NODAL R-HSA-1181150
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
G alpha (q) signalling events R-HSA-416476
ESR-mediated signaling R-HSA-8939211
Signal attenuation R-HSA-74749
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Growth hormone receptor signaling R-HSA-982772
GPCR downstream signalling R-HSA-388396
Negative regulation of MAPK pathway R-HSA-5675221
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR3 R-HSA-5654741
Signaling by TGF-beta Receptor Complex R-HSA-170834
ISG15 antiviral mechanism R-HSA-1169408
RUNX2 regulates bone development R-HSA-8941326
Toll-like Receptor Cascades R-HSA-168898
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Negative regulation of FGFR3 signaling R-HSA-5654732
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Disease R-HSA-1643685
Signaling by Nuclear Receptors R-HSA-9006931
Activation of the AP-1 family of transcription factors R-HSA-450341
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by FGFR1 R-HSA-5654736
Signaling by Activin R-HSA-1502540
Signaling by NTRKs R-HSA-166520
L1CAM interactions R-HSA-373760
MAPK3 (ERK1) activation R-HSA-110056
Interferon Signaling R-HSA-913531
Frs2-mediated activation R-HSA-170968
Signalling to ERKs R-HSA-187687
RNA Polymerase I Promoter Opening R-HSA-73728
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ALK in cancer R-HSA-9700206
Cell Cycle, Mitotic R-HSA-69278
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
NCAM signaling for neurite out-growth R-HSA-375165
Cellular responses to stress R-HSA-2262752
Signaling downstream of RAS mutants R-HSA-9649948
Negative regulation of the PI3K/AKT network R-HSA-199418
MyD88 cascade initiated on plasma membrane R-HSA-975871
Formation of apoptosome R-HSA-111458
ERK/MAPK targets R-HSA-198753
Response of Mtb to phagocytosis R-HSA-9637690
M Phase R-HSA-68886
Post NMDA receptor activation events R-HSA-438064
Transcriptional regulation by RUNX2 R-HSA-8878166
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Suppression of apoptosis R-HSA-9635465
Cellular Senescence R-HSA-2559583
Nervous system development R-HSA-9675108
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Hemostasis R-HSA-109582
Intrinsic Pathway for Apoptosis R-HSA-109606
RNA Polymerase I Promoter Clearance R-HSA-73854
Regulation of the apoptosome activity R-HSA-9627069
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-17 signaling R-HSA-448424
Innate Immune System R-HSA-168249
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Neuronal System R-HSA-112316
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF-independent MAPK1/3 activation R-HSA-112409
Leishmania phagocytosis R-HSA-9664417
MAPK family signaling cascades R-HSA-5683057
Generic Transcription Pathway R-HSA-212436
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Immune System R-HSA-168256
Signaling by TGFB family members R-HSA-9006936
Signal transduction by L1 R-HSA-445144
Signaling by FGFR4 R-HSA-5654743
Oxidative Stress Induced Senescence R-HSA-2559580
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Cytochrome c-mediated apoptotic response R-HSA-111461
MAP kinase activation R-HSA-450294
Insulin receptor signalling cascade R-HSA-74751
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Insulin receptor R-HSA-74752
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RNA Polymerase I Transcription R-HSA-73864
MyD88-independent TLR4 cascade R-HSA-166166
Transmission across Chemical Synapses R-HSA-112315
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by Interleukins R-HSA-449147
Signaling by FGFR2 R-HSA-5654738
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Leishmania infection R-HSA-9658195
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Apoptotic factor-mediated response R-HSA-111471
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by GPCR R-HSA-372790
RHO GTPase Effectors R-HSA-195258
Oncogene Induced Senescence R-HSA-2559585
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
PTEN Regulation R-HSA-6807070
Developmental Biology R-HSA-1266738
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Cellular response to heat stress R-HSA-3371556
NPAS4 regulates expression of target genes R-HSA-9768919
ERKs are inactivated R-HSA-202670
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Programmed Cell Death R-HSA-5357801
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MAP2K and MAPK activation R-HSA-5674135
RAF/MAP kinase cascade R-HSA-5673001
FCGR3A-mediated phagocytosis R-HSA-9664422
Negative regulation of FGFR1 signaling R-HSA-5654726
Parasite infection R-HSA-9664407
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
Signaling by MAP2K mutants R-HSA-9652169
Axon guidance R-HSA-422475
Infection with Mycobacterium tuberculosis R-HSA-9635486
Oncogenic MAPK signaling R-HSA-6802957
Apoptosis R-HSA-109581
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cell Cycle R-HSA-1640170
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Prolonged ERK activation events R-HSA-169893
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Negative regulation of FGFR4 signaling R-HSA-5654733
FCERI mediated MAPK activation R-HSA-2871796
Infectious disease R-HSA-5663205
Negative regulation of FGFR2 signaling R-HSA-5654727
Mitotic Prophase R-HSA-68875
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Signaling by FGFR R-HSA-190236
Transcriptional Regulation by NPAS4 R-HSA-9634815
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by NTRK1 (TRKA) R-HSA-187037
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
RSK activation R-HSA-444257
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Frs2-mediated activation R-HSA-170968
Cell Cycle, Mitotic R-HSA-69278
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by RAS mutants R-HSA-6802949
Interleukin-17 signaling R-HSA-448424
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Signaling by GPCR R-HSA-372790
Growth hormone receptor signaling R-HSA-982772
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by FGFR3 R-HSA-5654741
Suppression of apoptosis R-HSA-9635465
Transcriptional regulation by RUNX2 R-HSA-8878166
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
M Phase R-HSA-68886
Cellular response to heat stress R-HSA-3371556
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RSK activation R-HSA-444257
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by TGFB family members R-HSA-9006936
Signal transduction by L1 R-HSA-445144
FCGR3A-mediated phagocytosis R-HSA-9664422
Response of Mtb to phagocytosis R-HSA-9637690
Regulation of PTEN gene transcription R-HSA-8943724
Negative feedback regulation of MAPK pathway R-HSA-5674499
MAP2K and MAPK activation R-HSA-5674135
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Rho GTPases R-HSA-194315
Signaling by Insulin receptor R-HSA-74752
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Axon guidance R-HSA-422475
Programmed Cell Death R-HSA-5357801
NPAS4 regulates expression of target genes R-HSA-9768919
Neuronal System R-HSA-112316
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Hemostasis R-HSA-109582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Immune System R-HSA-168256
Cytochrome c-mediated apoptotic response R-HSA-111461
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal attenuation R-HSA-74749
Formation of apoptosome R-HSA-111458
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by ALK in cancer R-HSA-9700206
Signaling by Nuclear Receptors R-HSA-9006931
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cellular Senescence R-HSA-2559583
Signaling by MAP2K mutants R-HSA-9652169
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Transmission across Chemical Synapses R-HSA-112315
Signaling by FGFR R-HSA-190236
FCERI mediated MAPK activation R-HSA-2871796
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Cellular responses to stress R-HSA-2262752
Signaling by FGFR2 R-HSA-5654738
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
ERK/MAPK targets R-HSA-198753
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by NTRKs R-HSA-166520
Transcriptional Regulation by NPAS4 R-HSA-9634815
GPCR downstream signalling R-HSA-388396
MyD88-independent TLR4 cascade R-HSA-166166
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
PTEN Regulation R-HSA-6807070
Cell Cycle R-HSA-1640170
Negative regulation of FGFR1 signaling R-HSA-5654726
L1CAM interactions R-HSA-373760
Negative regulation of FGFR3 signaling R-HSA-5654732
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signalling to ERKs R-HSA-187687
Post NMDA receptor activation events R-HSA-438064
Oncogenic MAPK signaling R-HSA-6802957
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Interferon Signaling R-HSA-913531
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
RNA Polymerase I Promoter Opening R-HSA-73728
Activation of the AP-1 family of transcription factors R-HSA-450341
RNA Polymerase I Promoter Clearance R-HSA-73854
ERKs are inactivated R-HSA-202670
MyD88 dependent cascade initiated on endosome R-HSA-975155
ESR-mediated signaling R-HSA-8939211
Negative regulation of FGFR4 signaling R-HSA-5654733
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Activin R-HSA-1502540
Signaling by NTRK1 (TRKA) R-HSA-187037
Gene expression (Transcription) R-HSA-74160
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Negative regulation of FGFR2 signaling R-HSA-5654727
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK family signaling cascades R-HSA-5683057
Signaling by Interleukins R-HSA-449147
Insulin receptor signalling cascade R-HSA-74751
G alpha (q) signalling events R-HSA-416476
Signaling by NODAL R-HSA-1181150
PIP3 activates AKT signaling R-HSA-1257604
Regulation of the apoptosome activity R-HSA-9627069
Signaling by FGFR4 R-HSA-5654743
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK1/MAPK3 signaling R-HSA-5684996
NCAM signaling for neurite out-growth R-HSA-375165
Oncogene Induced Senescence R-HSA-2559585
Apoptosis R-HSA-109581
RNA Polymerase I Transcription R-HSA-73864
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Intrinsic Pathway for Apoptosis R-HSA-109606
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Parasite infection R-HSA-9664407
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Infection with Mycobacterium tuberculosis R-HSA-9635486
RHO GTPase Effectors R-HSA-195258
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Innate Immune System R-HSA-168249
Negative regulation of MAPK pathway R-HSA-5675221
Spry regulation of FGF signaling R-HSA-1295596
Leishmania phagocytosis R-HSA-9664417
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by FGFR1 R-HSA-5654736
MAP kinase activation R-HSA-450294
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by ALK fusions and activated point mutants R-HSA-9725370
ISG15 antiviral mechanism R-HSA-1169408
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Cytokine Signaling in Immune system R-HSA-1280215
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Negative regulation of the PI3K/AKT network R-HSA-199418
Toll-like Receptor Cascades R-HSA-168898
RAF/MAP kinase cascade R-HSA-5673001
Leishmania infection R-HSA-9658195
Generic Transcription Pathway R-HSA-212436
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Apoptotic factor-mediated response R-HSA-111471
MAPK3 (ERK1) activation R-HSA-110056
Platelet activation, signaling and aggregation R-HSA-76002
RUNX2 regulates bone development R-HSA-8941326
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Prolonged ERK activation events R-HSA-169893
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Growth hormone receptor signaling R-HSA-982772
MyD88 cascade initiated on plasma membrane R-HSA-975871
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
ISG15 antiviral mechanism R-HSA-1169408
Negative regulation of FGFR4 signaling R-HSA-5654733
Platelet activation, signaling and aggregation R-HSA-76002
RNA Polymerase I Promoter Opening R-HSA-73728
Parasite infection R-HSA-9664407
Axon guidance R-HSA-422475
RNA Polymerase I Promoter Clearance R-HSA-73854
Negative feedback regulation of MAPK pathway R-HSA-5674499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Prolonged ERK activation events R-HSA-169893
Toll-like Receptor Cascades R-HSA-168898
Signal transduction by L1 R-HSA-445144
Cellular Senescence R-HSA-2559583
NCAM signaling for neurite out-growth R-HSA-375165
L1CAM interactions R-HSA-373760
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Gene expression (Transcription) R-HSA-74160
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Signaling by NTRK1 (TRKA) R-HSA-187037
Cell Cycle R-HSA-1640170
Formation of apoptosome R-HSA-111458
Interleukin-17 signaling R-HSA-448424
Transcriptional regulation by RUNX2 R-HSA-8878166
NPAS4 regulates expression of target genes R-HSA-9768919
Hemostasis R-HSA-109582
Cellular responses to stimuli R-HSA-8953897
RAF-independent MAPK1/3 activation R-HSA-112409
Signalling to ERKs R-HSA-187687
Signaling by FGFR2 R-HSA-5654738
Negative regulation of MAPK pathway R-HSA-5675221
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Transmission across Chemical Synapses R-HSA-112315
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signaling by Insulin receptor R-HSA-74752
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Cytokine Signaling in Immune system R-HSA-1280215
ERK/MAPK targets R-HSA-198753
Signaling by Activin R-HSA-1502540
Interferon Signaling R-HSA-913531
Signaling by GPCR R-HSA-372790
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stress R-HSA-2262752
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Rho GTPases R-HSA-194315
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Transcriptional Regulation by NPAS4 R-HSA-9634815
RHO GTPase Effectors R-HSA-195258
Signal attenuation R-HSA-74749
Oncogenic MAPK signaling R-HSA-6802957
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling downstream of RAS mutants R-HSA-9649948
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAP kinase activation R-HSA-450294
Signaling by RAS mutants R-HSA-6802949
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Leishmania infection R-HSA-9658195
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by FGFR4 R-HSA-5654743
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by NODAL R-HSA-1181150
RUNX2 regulates bone development R-HSA-8941326
ERKs are inactivated R-HSA-202670
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by MAP2K mutants R-HSA-9652169
Signaling by FGFR1 R-HSA-5654736
Signaling by TGF-beta Receptor Complex R-HSA-170834
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Extra-nuclear estrogen signaling R-HSA-9009391
Nervous system development R-HSA-9675108
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Oncogene Induced Senescence R-HSA-2559585
Cell Cycle, Mitotic R-HSA-69278
Disease R-HSA-1643685
Signaling by FGFR3 R-HSA-5654741
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
PIP3 activates AKT signaling R-HSA-1257604
ESR-mediated signaling R-HSA-8939211
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RSK activation R-HSA-444257
Immune System R-HSA-168256
RAF/MAP kinase cascade R-HSA-5673001
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by NTRKs R-HSA-166520
Apoptotic factor-mediated response R-HSA-111471
Negative regulation of FGFR1 signaling R-HSA-5654726
Leishmania phagocytosis R-HSA-9664417
Programmed Cell Death R-HSA-5357801
Signaling by TGFB family members R-HSA-9006936
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Innate Immune System R-HSA-168249
Neuronal System R-HSA-112316
Oxidative Stress Induced Senescence R-HSA-2559580
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RNA Polymerase II Transcription R-HSA-73857
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Cytochrome c-mediated apoptotic response R-HSA-111461
M Phase R-HSA-68886
Post NMDA receptor activation events R-HSA-438064
G alpha (q) signalling events R-HSA-416476
Spry regulation of FGF signaling R-HSA-1295596
FCERI mediated MAPK activation R-HSA-2871796
PTEN Regulation R-HSA-6807070
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Cellular response to heat stress R-HSA-3371556
Suppression of apoptosis R-HSA-9635465
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Response of Mtb to phagocytosis R-HSA-9637690
MAPK3 (ERK1) activation R-HSA-110056
Signaling by RAF1 mutants R-HSA-9656223
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MAP2K and MAPK activation R-HSA-5674135
Signaling by ALK in cancer R-HSA-9700206
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR R-HSA-190236
Intracellular signaling by second messengers R-HSA-9006925
Regulation of the apoptosome activity R-HSA-9627069
Infectious disease R-HSA-5663205
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
RNA Polymerase I Transcription R-HSA-73864
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Negative regulation of FGFR2 signaling R-HSA-5654727
FCGR3A-mediated phagocytosis R-HSA-9664422
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Developmental Biology R-HSA-1266738
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Apoptosis R-HSA-109581
Signaling by ALK fusions and activated point mutants R-HSA-9725370
MAPK family signaling cascades R-HSA-5683057
Frs2-mediated activation R-HSA-170968
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
Mitotic Prophase R-HSA-68875
Negative regulation of the PI3K/AKT network R-HSA-199418
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Regulation of the apoptosome activity R-HSA-9627069
Signaling by RAF1 mutants R-HSA-9656223
Parasite infection R-HSA-9664407
Signaling by NTRKs R-HSA-166520
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Generic Transcription Pathway R-HSA-212436
Signaling by NODAL R-HSA-1181150
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
FCGR3A-mediated phagocytosis R-HSA-9664422
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Apoptosis R-HSA-109581
Oncogenic MAPK signaling R-HSA-6802957
Signaling by MAP2K mutants R-HSA-9652169
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Signaling by FGFR4 R-HSA-5654743
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Apoptotic factor-mediated response R-HSA-111471
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by FGFR2 R-HSA-5654738
Negative feedback regulation of MAPK pathway R-HSA-5674499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NCAM signaling for neurite out-growth R-HSA-375165
RNA Polymerase I Transcription R-HSA-73864
Cellular response to heat stress R-HSA-3371556
Neuronal System R-HSA-112316
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MyD88 cascade initiated on plasma membrane R-HSA-975871
RNA Polymerase I Promoter Clearance R-HSA-73854
Cell Cycle, Mitotic R-HSA-69278
RSK activation R-HSA-444257
Programmed Cell Death R-HSA-5357801
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signal transduction by L1 R-HSA-445144
Infectious disease R-HSA-5663205
Formation of apoptosome R-HSA-111458
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RUNX2 regulates osteoblast differentiation R-HSA-8940973
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by Insulin receptor R-HSA-74752
Regulation of PTEN gene transcription R-HSA-8943724
Interferon Signaling R-HSA-913531
Oxidative Stress Induced Senescence R-HSA-2559580
NPAS4 regulates expression of target genes R-HSA-9768919
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling downstream of RAS mutants R-HSA-9649948
Frs2-mediated activation R-HSA-170968
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 dependent cascade initiated on endosome R-HSA-975155
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
MAP kinase activation R-HSA-450294
RNA Polymerase I Promoter Opening R-HSA-73728
Signaling by BRAF and RAF1 fusions R-HSA-6802952
ISG15 antiviral mechanism R-HSA-1169408
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
ERKs are inactivated R-HSA-202670
Leishmania phagocytosis R-HSA-9664417
Leishmania infection R-HSA-9658195
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FGFR R-HSA-190236
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
L1CAM interactions R-HSA-373760
Insulin receptor signalling cascade R-HSA-74751
MAPK family signaling cascades R-HSA-5683057
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular responses to stimuli R-HSA-8953897
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signal attenuation R-HSA-74749
Intracellular signaling by second messengers R-HSA-9006925
Growth hormone receptor signaling R-HSA-982772
Signaling by NTRK1 (TRKA) R-HSA-187037
Prolonged ERK activation events R-HSA-169893
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAP2K and MAPK activation R-HSA-5674135
RAF/MAP kinase cascade R-HSA-5673001
Hemostasis R-HSA-109582
Toll-like Receptor Cascades R-HSA-168898
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by Rho GTPases R-HSA-194315
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Axon guidance R-HSA-422475
MAPK3 (ERK1) activation R-HSA-110056
Signaling by FGFR3 R-HSA-5654741
ESR-mediated signaling R-HSA-8939211
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
M Phase R-HSA-68886
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RHO GTPase Effectors R-HSA-195258
Mitotic Prophase R-HSA-68875
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by RAS mutants R-HSA-6802949
Platelet activation, signaling and aggregation R-HSA-76002
Innate Immune System R-HSA-168249
Post NMDA receptor activation events R-HSA-438064
Negative regulation of FGFR3 signaling R-HSA-5654732
Oncogene Induced Senescence R-HSA-2559585
Negative regulation of FGFR2 signaling R-HSA-5654727
Signalling to ERKs R-HSA-187687
Cellular Senescence R-HSA-2559583
Signaling by ALK in cancer R-HSA-9700206
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Activin R-HSA-1502540
Transcriptional regulation by RUNX2 R-HSA-8878166
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by FGFR1 R-HSA-5654736
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Interleukins R-HSA-449147
Negative regulation of MAPK pathway R-HSA-5675221
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Transmission across Chemical Synapses R-HSA-112315
FCERI mediated MAPK activation R-HSA-2871796
Suppression of apoptosis R-HSA-9635465
RUNX2 regulates bone development R-HSA-8941326
Signaling by TGF-beta Receptor Complex R-HSA-170834
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Response of Mtb to phagocytosis R-HSA-9637690
Transcriptional Regulation by NPAS4 R-HSA-9634815
RAF-independent MAPK1/3 activation R-HSA-112409
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
ERK/MAPK targets R-HSA-198753
Signaling by TGFB family members R-HSA-9006936
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Spry regulation of FGF signaling R-HSA-1295596
PIP3 activates AKT signaling R-HSA-1257604
Activation of the AP-1 family of transcription factors R-HSA-450341
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
RNA Polymerase II Transcription R-HSA-73857
Extra-nuclear estrogen signaling R-HSA-9009391
Interleukin-17 signaling R-HSA-448424
FCERI mediated MAPK activation R-HSA-2871796
Developmental Biology R-HSA-1266738
Signaling by NTRK1 (TRKA) R-HSA-187037
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR4 signaling R-HSA-5654733
Prolonged ERK activation events R-HSA-169893
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cellular responses to stress R-HSA-2262752
Signaling by GPCR R-HSA-372790
Negative feedback regulation of MAPK pathway R-HSA-5674499
RNA Polymerase I Transcription R-HSA-73864
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by TGFB family members R-HSA-9006936
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll-like Receptor Cascades R-HSA-168898
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
M Phase R-HSA-68886
Signaling by FGFR4 R-HSA-5654743
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Apoptosis R-HSA-109581
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of NMDA receptors and postsynaptic events R-HSA-442755
ESR-mediated signaling R-HSA-8939211
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Activin R-HSA-1502540
Cytokine Signaling in Immune system R-HSA-1280215
Oncogene Induced Senescence R-HSA-2559585
MAP kinase activation R-HSA-450294
Immune System R-HSA-168256
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MAPK3 (ERK1) activation R-HSA-110056
Neuronal System R-HSA-112316
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MAPK family signaling cascades R-HSA-5683057
Signaling by TGF-beta Receptor Complex R-HSA-170834
Negative regulation of MAPK pathway R-HSA-5675221
RUNX2 regulates bone development R-HSA-8941326
Interferon Signaling R-HSA-913531
RAF-independent MAPK1/3 activation R-HSA-112409
Generic Transcription Pathway R-HSA-212436
Signaling by FGFR R-HSA-190236
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Infection with Mycobacterium tuberculosis R-HSA-9635486
Negative regulation of FGFR1 signaling R-HSA-5654726
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Cellular responses to stimuli R-HSA-8953897
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular Senescence R-HSA-2559583
MyD88 cascade initiated on plasma membrane R-HSA-975871
Intracellular signaling by second messengers R-HSA-9006925
Signalling to ERKs R-HSA-187687
Signal attenuation R-HSA-74749
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Leishmania infection R-HSA-9658195
Regulation of the apoptosome activity R-HSA-9627069
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
MyD88 dependent cascade initiated on endosome R-HSA-975155
Hemostasis R-HSA-109582
Signaling by Nuclear Receptors R-HSA-9006931
Frs2-mediated activation R-HSA-170968
Post NMDA receptor activation events R-HSA-438064
Transmission across Chemical Synapses R-HSA-112315
Signaling by NODAL R-HSA-1181150
Suppression of apoptosis R-HSA-9635465
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by FGFR3 R-HSA-5654741
Infectious disease R-HSA-5663205
Signaling by ALK in cancer R-HSA-9700206
GPCR downstream signalling R-HSA-388396
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Transcriptional regulation by RUNX2 R-HSA-8878166
RSK activation R-HSA-444257
FCGR3A-mediated phagocytosis R-HSA-9664422
Oncogenic MAPK signaling R-HSA-6802957
Formation of apoptosome R-HSA-111458
Negative regulation of FGFR2 signaling R-HSA-5654727
Regulation of PTEN gene transcription R-HSA-8943724
Programmed Cell Death R-HSA-5357801
Signal transduction by L1 R-HSA-445144
Interleukin-17 signaling R-HSA-448424
Signaling by Rho GTPases R-HSA-194315
Cell Cycle, Mitotic R-HSA-69278
Insulin receptor signalling cascade R-HSA-74751
Negative regulation of the PI3K/AKT network R-HSA-199418
MAP2K and MAPK activation R-HSA-5674135
NPAS4 regulates expression of target genes R-HSA-9768919
Transcriptional Regulation by NPAS4 R-HSA-9634815
Activation of the AP-1 family of transcription factors R-HSA-450341
Disease R-HSA-1643685
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Negative regulation of FGFR3 signaling R-HSA-5654732
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by RAF1 mutants R-HSA-9656223
Intrinsic Pathway for Apoptosis R-HSA-109606
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Extra-nuclear estrogen signaling R-HSA-9009391
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Response of Mtb to phagocytosis R-HSA-9637690
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MAPK1/MAPK3 signaling R-HSA-5684996
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Mitotic Prophase R-HSA-68875
RHO GTPase Effectors R-HSA-195258
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by MAP2K mutants R-HSA-9652169
MyD88-independent TLR4 cascade R-HSA-166166
RAF/MAP kinase cascade R-HSA-5673001
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Oxidative Stress Induced Senescence R-HSA-2559580
Apoptotic factor-mediated response R-HSA-111471
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Axon guidance R-HSA-422475
L1CAM interactions R-HSA-373760
Leishmania phagocytosis R-HSA-9664417
Signal Transduction R-HSA-162582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Spry regulation of FGF signaling R-HSA-1295596
ERKs are inactivated R-HSA-202670
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by NTRKs R-HSA-166520
Growth hormone receptor signaling R-HSA-982772
Signaling by Insulin receptor R-HSA-74752
Parasite infection R-HSA-9664407
Signaling by RAS mutants R-HSA-6802949
Innate Immune System R-HSA-168249
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by FGFR2 R-HSA-5654738
Cytochrome c-mediated apoptotic response R-HSA-111461
RNA Polymerase I Promoter Opening R-HSA-73728
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by FGFR1 R-HSA-5654736
Nervous system development R-HSA-9675108
ISG15 antiviral mechanism R-HSA-1169408
Cell Cycle R-HSA-1640170
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Transcriptional Regulation by NPAS4 R-HSA-9634815
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
ESR-mediated signaling R-HSA-8939211
MAP2K and MAPK activation R-HSA-5674135
Developmental Biology R-HSA-1266738
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
RNA Polymerase I Promoter Opening R-HSA-73728
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Interleukin-17 signaling R-HSA-448424
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Neuronal System R-HSA-112316
RSK activation R-HSA-444257
MyD88-independent TLR4 cascade R-HSA-166166
Post NMDA receptor activation events R-HSA-438064
Signaling by Insulin receptor R-HSA-74752
RUNX2 regulates bone development R-HSA-8941326
Oxidative Stress Induced Senescence R-HSA-2559580
Activation of the AP-1 family of transcription factors R-HSA-450341
Activation of NMDA receptors and postsynaptic events R-HSA-442755
M Phase R-HSA-68886
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Activin R-HSA-1502540
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signal attenuation R-HSA-74749
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Interferon Signaling R-HSA-913531
Growth hormone receptor signaling R-HSA-982772
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by FGFR4 R-HSA-5654743
Signaling by RAF1 mutants R-HSA-9656223
Oncogenic MAPK signaling R-HSA-6802957
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Spry regulation of FGF signaling R-HSA-1295596
MAP kinase activation R-HSA-450294
Apoptotic factor-mediated response R-HSA-111471
RNA Polymerase II Transcription R-HSA-73857
Infection with Mycobacterium tuberculosis R-HSA-9635486
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
FCGR3A-mediated phagocytosis R-HSA-9664422
GPCR downstream signalling R-HSA-388396
Signaling by FGFR3 R-HSA-5654741
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Innate Immune System R-HSA-168249
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR1 R-HSA-5654736
ERK/MAPK targets R-HSA-198753
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Extra-nuclear estrogen signaling R-HSA-9009391
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RUNX2 regulates osteoblast differentiation R-HSA-8940973
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by NTRKs R-HSA-166520
Leishmania infection R-HSA-9658195
Programmed Cell Death R-HSA-5357801
Parasite infection R-HSA-9664407
MyD88 dependent cascade initiated on endosome R-HSA-975155
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by TGFB family members R-HSA-9006936
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NCAM signaling for neurite out-growth R-HSA-375165
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
L1CAM interactions R-HSA-373760
Signal Transduction R-HSA-162582
Frs2-mediated activation R-HSA-170968
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll-like Receptor Cascades R-HSA-168898
Negative regulation of MAPK pathway R-HSA-5675221
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
FCERI mediated MAPK activation R-HSA-2871796
Signaling by MAP2K mutants R-HSA-9652169
Signaling by ALK in cancer R-HSA-9700206
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Cellular Senescence R-HSA-2559583
Infectious disease R-HSA-5663205
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Generic Transcription Pathway R-HSA-212436
Intrinsic Pathway for Apoptosis R-HSA-109606
Mitotic Prophase R-HSA-68875
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by GPCR R-HSA-372790
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling downstream of RAS mutants R-HSA-9649948
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RNA Polymerase I Transcription R-HSA-73864
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by RAS mutants R-HSA-6802949
ERKs are inactivated R-HSA-202670
Cell Cycle, Mitotic R-HSA-69278
Regulation of PTEN gene transcription R-HSA-8943724
Negative regulation of FGFR3 signaling R-HSA-5654732
MAPK family signaling cascades R-HSA-5683057
Negative regulation of FGFR1 signaling R-HSA-5654726
RAF/MAP kinase cascade R-HSA-5673001
Formation of apoptosome R-HSA-111458
Signaling by Nuclear Receptors R-HSA-9006931
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by NTRK1 (TRKA) R-HSA-187037
Immune System R-HSA-168256
Signaling by TGF-beta Receptor Complex R-HSA-170834
PIP3 activates AKT signaling R-HSA-1257604
MAPK3 (ERK1) activation R-HSA-110056
RAF-independent MAPK1/3 activation R-HSA-112409
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
MAPK1/MAPK3 signaling R-HSA-5684996
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cytochrome c-mediated apoptotic response R-HSA-111461
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of the apoptosome activity R-HSA-9627069
Signal transduction by L1 R-HSA-445144
Hemostasis R-HSA-109582
Oncogene Induced Senescence R-HSA-2559585
RHO GTPase Effectors R-HSA-195258
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Suppression of apoptosis R-HSA-9635465
Signaling by FGFR R-HSA-190236
Apoptosis R-HSA-109581
G alpha (q) signalling events R-HSA-416476
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Nervous system development R-HSA-9675108
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
PTEN Regulation R-HSA-6807070
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by FGFR2 R-HSA-5654738
Prolonged ERK activation events R-HSA-169893
Negative regulation of FGFR4 signaling R-HSA-5654733
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular response to heat stress R-HSA-3371556
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by Rho GTPases R-HSA-194315
Signaling by NODAL R-HSA-1181150
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Transmission across Chemical Synapses R-HSA-112315
Leishmania phagocytosis R-HSA-9664417
Response of Mtb to phagocytosis R-HSA-9637690
Cellular responses to stimuli R-HSA-8953897
Signalling to ERKs R-HSA-187687
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
FCGR3A-mediated phagocytosis R-HSA-9664422
Prolonged ERK activation events R-HSA-169893
Programmed Cell Death R-HSA-5357801
Signaling by NTRKs R-HSA-166520
Negative regulation of FGFR2 signaling R-HSA-5654727
Neuronal System R-HSA-112316
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Activin R-HSA-1502540
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by FGFR4 R-HSA-5654743
Apoptotic factor-mediated response R-HSA-111471
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Oncogene Induced Senescence R-HSA-2559585
Response of Mtb to phagocytosis R-HSA-9637690
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
ERKs are inactivated R-HSA-202670
Apoptosis R-HSA-109581
RHO GTPase Effectors R-HSA-195258
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by ALK fusions and activated point mutants R-HSA-9725370
RNA Polymerase II Transcription R-HSA-73857
MyD88 dependent cascade initiated on endosome R-HSA-975155
Formation of apoptosome R-HSA-111458
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Extra-nuclear estrogen signaling R-HSA-9009391
RSK activation R-HSA-444257
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Toll-like Receptor Cascades R-HSA-168898
Cell Cycle R-HSA-1640170
Innate Immune System R-HSA-168249
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Axon guidance R-HSA-422475
Signaling by ALK in cancer R-HSA-9700206
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
L1CAM interactions R-HSA-373760
Infection with Mycobacterium tuberculosis R-HSA-9635486
RNA Polymerase I Promoter Opening R-HSA-73728
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Frs2-mediated activation R-HSA-170968
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Hemostasis R-HSA-109582
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR3 R-HSA-5654741
ESR-mediated signaling R-HSA-8939211
Signaling by FGFR R-HSA-190236
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
RNA Polymerase I Transcription R-HSA-73864
Signaling by RAF1 mutants R-HSA-9656223
MAPK family signaling cascades R-HSA-5683057
Cellular Senescence R-HSA-2559583
Platelet activation, signaling and aggregation R-HSA-76002
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by NODAL R-HSA-1181150
Signalling to ERKs R-HSA-187687
Nervous system development R-HSA-9675108
Negative regulation of MAPK pathway R-HSA-5675221
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cell Cycle, Mitotic R-HSA-69278
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G alpha (q) signalling events R-HSA-416476
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Signaling by FGFR1 R-HSA-5654736
Insulin receptor signalling cascade R-HSA-74751
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Spry regulation of FGF signaling R-HSA-1295596
Cellular responses to stress R-HSA-2262752
GPCR downstream signalling R-HSA-388396
Intracellular signaling by second messengers R-HSA-9006925
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
MAP2K and MAPK activation R-HSA-5674135
Signaling by FGFR2 R-HSA-5654738
RUNX2 regulates bone development R-HSA-8941326
Activation of the AP-1 family of transcription factors R-HSA-450341
Suppression of apoptosis R-HSA-9635465
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling downstream of RAS mutants R-HSA-9649948
Interleukin-17 signaling R-HSA-448424
Disease R-HSA-1643685
Leishmania infection R-HSA-9658195
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signal attenuation R-HSA-74749
Signaling by Nuclear Receptors R-HSA-9006931
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by RAS mutants R-HSA-6802949
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK3 (ERK1) activation R-HSA-110056
Signaling by Rho GTPases R-HSA-194315
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Regulation of the apoptosome activity R-HSA-9627069
Growth hormone receptor signaling R-HSA-982772
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by MAP2K mutants R-HSA-9652169
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
ERK/MAPK targets R-HSA-198753
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Leishmania phagocytosis R-HSA-9664417
Cellular responses to stimuli R-HSA-8953897
Signaling by Interleukins R-HSA-449147
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signal transduction by L1 R-HSA-445144
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by GPCR R-HSA-372790
Negative feedback regulation of MAPK pathway R-HSA-5674499
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Negative regulation of FGFR1 signaling R-HSA-5654726
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RNA Polymerase I Promoter Clearance R-HSA-73854
Parasite infection R-HSA-9664407
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by TGFB family members R-HSA-9006936
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated MAPK activation R-HSA-2871796
MAP kinase activation R-HSA-450294
Transcriptional Regulation by NPAS4 R-HSA-9634815
Negative regulation of the PI3K/AKT network R-HSA-199418
Interferon Signaling R-HSA-913531
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intrinsic Pathway for Apoptosis R-HSA-109606
Post NMDA receptor activation events R-HSA-438064
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Infectious disease R-HSA-5663205
Transmission across Chemical Synapses R-HSA-112315
Regulation of PTEN gene transcription R-HSA-8943724
Oncogenic MAPK signaling R-HSA-6802957
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Extra-nuclear estrogen signaling R-HSA-9009391
Interferon Signaling R-HSA-913531
Transmission across Chemical Synapses R-HSA-112315
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR1 R-HSA-5654736
Apoptotic factor-mediated response R-HSA-111471
Signal transduction by L1 R-HSA-445144
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Rho GTPases R-HSA-194315
Leishmania phagocytosis R-HSA-9664417
MAPK family signaling cascades R-HSA-5683057
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
RNA Polymerase I Promoter Opening R-HSA-73728
Signaling by NODAL R-HSA-1181150
Immune System R-HSA-168256
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Post NMDA receptor activation events R-HSA-438064
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Hemostasis R-HSA-109582
Suppression of apoptosis R-HSA-9635465
Activation of the AP-1 family of transcription factors R-HSA-450341
PTEN Regulation R-HSA-6807070
Programmed Cell Death R-HSA-5357801
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by NTRKs R-HSA-166520
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Oncogenic MAPK signaling R-HSA-6802957
RNA Polymerase I Transcription R-HSA-73864
Interleukin-17 signaling R-HSA-448424
ISG15 antiviral mechanism R-HSA-1169408
Signaling by FGFR4 R-HSA-5654743
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Negative regulation of the PI3K/AKT network R-HSA-199418
Platelet activation, signaling and aggregation R-HSA-76002
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Insulin receptor R-HSA-74752
FCERI mediated MAPK activation R-HSA-2871796
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Frs2-mediated activation R-HSA-170968
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling downstream of RAS mutants R-HSA-9649948
Developmental Biology R-HSA-1266738
Negative regulation of FGFR1 signaling R-HSA-5654726
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Nuclear Receptors R-HSA-9006931
Mitotic Prophase R-HSA-68875
Neuronal System R-HSA-112316
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Growth hormone receptor signaling R-HSA-982772
MAP kinase activation R-HSA-450294
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll-like Receptor Cascades R-HSA-168898
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
MAPK3 (ERK1) activation R-HSA-110056
Signaling by FGFR3 R-HSA-5654741
Signaling by FGFR2 R-HSA-5654738
Parasite infection R-HSA-9664407
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by ALK in cancer R-HSA-9700206
Signaling by TGFB family members R-HSA-9006936
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by RAS mutants R-HSA-6802949
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
RUNX2 regulates bone development R-HSA-8941326
L1CAM interactions R-HSA-373760
Gene expression (Transcription) R-HSA-74160
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Prolonged ERK activation events R-HSA-169893
ERK/MAPK targets R-HSA-198753
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Oncogene Induced Senescence R-HSA-2559585
Negative feedback regulation of MAPK pathway R-HSA-5674499
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cellular response to heat stress R-HSA-3371556
Transcriptional regulation by RUNX2 R-HSA-8878166
Response of Mtb to phagocytosis R-HSA-9637690
Intracellular signaling by second messengers R-HSA-9006925
RAF-independent MAPK1/3 activation R-HSA-112409
RSK activation R-HSA-444257
Signaling by MAP2K mutants R-HSA-9652169
Nervous system development R-HSA-9675108
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Negative regulation of FGFR2 signaling R-HSA-5654727
MyD88 cascade initiated on plasma membrane R-HSA-975871
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of FGFR4 signaling R-HSA-5654733
Oxidative Stress Induced Senescence R-HSA-2559580
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR R-HSA-190236
Signaling by GPCR R-HSA-372790
Signaling by TGF-beta Receptor Complex R-HSA-170834
GPCR downstream signalling R-HSA-388396
Negative regulation of MAPK pathway R-HSA-5675221
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
M Phase R-HSA-68886
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Apoptosis R-HSA-109581
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Leishmania infection R-HSA-9658195
Intrinsic Pathway for Apoptosis R-HSA-109606
MyD88-independent TLR4 cascade R-HSA-166166
MAP2K and MAPK activation R-HSA-5674135
ERKs are inactivated R-HSA-202670
ESR-mediated signaling R-HSA-8939211
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
NPAS4 regulates expression of target genes R-HSA-9768919
Cellular responses to stimuli R-HSA-8953897
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Cellular Senescence R-HSA-2559583
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signalling to ERKs R-HSA-187687
Spry regulation of FGF signaling R-HSA-1295596
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Innate Immune System R-HSA-168249
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Signaling by NTRK1 (TRKA) R-HSA-187037
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
PIP3 activates AKT signaling R-HSA-1257604
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Formation of apoptosome R-HSA-111458
Regulation of the apoptosome activity R-HSA-9627069
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
RHO GTPase Effectors R-HSA-195258
MAPK1/MAPK3 signaling R-HSA-5684996
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signal attenuation R-HSA-74749
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of PTEN gene transcription R-HSA-8943724
Infection with Mycobacterium tuberculosis R-HSA-9635486
G alpha (q) signalling events R-HSA-416476
Signaling by Activin R-HSA-1502540
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR4 R-HSA-5654743
RNA Polymerase I Promoter Clearance R-HSA-73854
Activation of the AP-1 family of transcription factors R-HSA-450341
Infection with Mycobacterium tuberculosis R-HSA-9635486
Mitotic Prophase R-HSA-68875
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
MyD88-independent TLR4 cascade R-HSA-166166
PIP3 activates AKT signaling R-HSA-1257604
Regulation of HSF1-mediated heat shock response R-HSA-3371453
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by MAP2K mutants R-HSA-9652169
RSK activation R-HSA-444257
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MAPK family signaling cascades R-HSA-5683057
Signaling by NTRKs R-HSA-166520
Signaling by FGFR3 R-HSA-5654741
Developmental Biology R-HSA-1266738
Oncogenic MAPK signaling R-HSA-6802957
Suppression of apoptosis R-HSA-9635465
ERK/MAPK targets R-HSA-198753
Spry regulation of FGF signaling R-HSA-1295596
Disease R-HSA-1643685
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cell Cycle, Mitotic R-HSA-69278
Signaling by NTRK1 (TRKA) R-HSA-187037
Programmed Cell Death R-HSA-5357801
Axon guidance R-HSA-422475
Signaling downstream of RAS mutants R-HSA-9649948
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Oncogene Induced Senescence R-HSA-2559585
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Extra-nuclear estrogen signaling R-HSA-9009391
Signal transduction by L1 R-HSA-445144
Toll-like Receptor Cascades R-HSA-168898
Cellular response to heat stress R-HSA-3371556
Regulation of PTEN gene transcription R-HSA-8943724
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Prolonged ERK activation events R-HSA-169893
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Transmission across Chemical Synapses R-HSA-112315
Parasite infection R-HSA-9664407
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Generic Transcription Pathway R-HSA-212436
Negative regulation of the PI3K/AKT network R-HSA-199418
Cellular responses to stress R-HSA-2262752
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Frs2-mediated activation R-HSA-170968
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Intrinsic Pathway for Apoptosis R-HSA-109606
Formation of apoptosome R-HSA-111458
ISG15 antiviral mechanism R-HSA-1169408
Negative regulation of FGFR1 signaling R-HSA-5654726
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Cytokine Signaling in Immune system R-HSA-1280215
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAP kinase activation R-HSA-450294
RNA Polymerase I Promoter Opening R-HSA-73728
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
NCAM signaling for neurite out-growth R-HSA-375165
Leishmania phagocytosis R-HSA-9664417
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Interferon Signaling R-HSA-913531
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR2 signaling R-HSA-5654727
RUNX2 regulates bone development R-HSA-8941326
Interleukin-17 signaling R-HSA-448424
Immune System R-HSA-168256
Signaling by Insulin receptor R-HSA-74752
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Insulin receptor signalling cascade R-HSA-74751
Signaling by NODAL R-HSA-1181150
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Negative regulation of MAPK pathway R-HSA-5675221
Signal Transduction R-HSA-162582
Regulation of the apoptosome activity R-HSA-9627069
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Post NMDA receptor activation events R-HSA-438064
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Apoptotic factor-mediated response R-HSA-111471
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signal attenuation R-HSA-74749
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Hemostasis R-HSA-109582
MAP2K and MAPK activation R-HSA-5674135
ERKs are inactivated R-HSA-202670
Growth hormone receptor signaling R-HSA-982772
L1CAM interactions R-HSA-373760
Signaling by Rho GTPases R-HSA-194315
ESR-mediated signaling R-HSA-8939211
FCERI mediated MAPK activation R-HSA-2871796
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Response of Mtb to phagocytosis R-HSA-9637690
Neuronal System R-HSA-112316
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Cell Cycle R-HSA-1640170
RHO GTPase Effectors R-HSA-195258
Signaling by Nuclear Receptors R-HSA-9006931
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Oxidative Stress Induced Senescence R-HSA-2559580
Apoptosis R-HSA-109581
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signalling to ERKs R-HSA-187687
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
GPCR downstream signalling R-HSA-388396
RNA Polymerase I Transcription R-HSA-73864
Signaling by FGFR2 R-HSA-5654738
PTEN Regulation R-HSA-6807070
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by RAS mutants R-HSA-6802949
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by FGFR R-HSA-190236
Cytochrome c-mediated apoptotic response R-HSA-111461
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by ALK in cancer R-HSA-9700206
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by RAF1 mutants R-HSA-9656223
Cellular Senescence R-HSA-2559583
Transcriptional Regulation by NPAS4 R-HSA-9634815
Negative feedback regulation of MAPK pathway R-HSA-5674499
Cellular responses to stimuli R-HSA-8953897
Signaling by FGFR1 R-HSA-5654736
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by TGFB family members R-HSA-9006936
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Gene expression (Transcription) R-HSA-74160
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Leishmania infection R-HSA-9658195
Signaling by GPCR R-HSA-372790
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Activin R-HSA-1502540
MyD88 cascade initiated on plasma membrane R-HSA-975871
Negative regulation of FGFR3 signaling R-HSA-5654732
MAPK3 (ERK1) activation R-HSA-110056

Expression Atlas ENSG00000102882
NCBI gene (formerly Entrezgene) 5595
GeneCards 6877
HGNC Symbol HGNC:6877
MIM gene 601795
UniProtKB Gene Name P27361
WikiGene 5595